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<meta name="keywords" content="C5543614, disease or syndrome, lmphm11, lymphatic malformation 11, tie1, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Lymphatic malformation-11 (LMPHM11) is characterized by lower extremity edema, with onset in the second or third decade of life. Some affected individuals may have subclinical lymphatic malformations (Michelini et al., 2020). For a discussion of genetic heterogeneity of lymphatic malformation, see LMPHM1 (153100)." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Lymphatic malformation 11 (Concept Id: C5543614)
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||
<!--
|
||
UID=1784862
|
||
ConceptID=C5543614
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Lymphatic malformation 11<span class="h1sub">(LMPHM11)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1784862</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C5543614</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>LMPHM11; LYMPHATIC MALFORMATION 11</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="TIE1 - ID: 7075 - NCBI Gene" href="/gene/7075" class="medgenPMinfo">TIE1</a> (1p34.2)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0030316" target="_blank">MONDO:0030316</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/619401" target="_blank">619401</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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||
<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Lymphatic malformation-11 (LMPHM11) is characterized by lower extremity edema, with onset in the second or third decade of life. Some affected individuals may have subclinical lymphatic malformations (Michelini et al., 2020). For a discussion of genetic heterogeneity of lymphatic malformation, see LMPHM1 (153100). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_116085"><div><strong>Pedal edema</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>116085</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0239340</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An abnormal accumulation of excess fluid in the lower extremity resulting in swelling of the feet and extending upward to the lower leg.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/116085">Feature record</a> | <a href="/medgen?term=%22Pedal%20edema%22%5BClinical%20Features%5D%20OR%20116085%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_6155"><div><strong>Lymphedema</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>6155</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0024236</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Localized fluid retention and tissue swelling caused by a compromised lymphatic system.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/6155">Feature record</a> | <a href="/medgen?term=%22Lymphedema%22%5BClinical%20Features%5D%20OR%206155%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of limbs</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_116085" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pedal edema</a></span></li></ul></li><li><span class="TLline">Abnormality of metabolism/homeostasis</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_6155" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lymphedema</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36672900">Prenatal Screening and Diagnostic Considerations for 22q11.2 Microdeletions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Blagowidow N,
|
||
Nowakowska B,
|
||
Schindewolf E,
|
||
Grati FR,
|
||
Putotto C,
|
||
Breckpot J,
|
||
Swillen A,
|
||
Crowley TB,
|
||
Loo JCY,
|
||
Lairson LA,
|
||
Óskarsdóttir S,
|
||
Boot E,
|
||
Garcia-Minaur S,
|
||
Cristina Digilio M,
|
||
Marino B,
|
||
Coleman B,
|
||
Moldenhauer JS,
|
||
Bassett AS,
|
||
McDonald-McGinn DM</span><br />
|
||
<span class="medgenPMjournal">Genes (Basel)</span>
|
||
2023 Jan 6;14(1)
|
||
doi: 10.3390/genes14010160.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36672900" target="_blank">36672900</a><a href="/pmc/articles/PMC9858737" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32022400">Congenital heart defects in Noonan syndrome: Diagnosis, management, and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Linglart L,
|
||
Gelb BD</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet C Semin Med Genet</span>
|
||
2020 Mar;184(1):73-80.
|
||
Epub 2020 Feb 5
|
||
doi: 10.1002/ajmg.c.31765.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32022400" target="_blank">32022400</a><a href="/pmc/articles/PMC7682536" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21742796">Normalization of the vasculature for treatment of cancer and other diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Goel S,
|
||
Duda DG,
|
||
Xu L,
|
||
Munn LL,
|
||
Boucher Y,
|
||
Fukumura D,
|
||
Jain RK</span><br />
|
||
<span class="medgenPMjournal">Physiol Rev</span>
|
||
2011 Jul;91(3):1071-121.
|
||
doi: 10.1152/physrev.00038.2010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21742796" target="_blank">21742796</a><a href="/pmc/articles/PMC3258432" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(lymphatic%20malformation%2011)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (82)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36715578">Similar grey matter abnormalities in 22q11.2DS and chronic schizophrenia: a voxel-based morphometry study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Frascarelli M,
|
||
Accinni T,
|
||
Buzzanca A,
|
||
Di Bonaventura C,
|
||
Fanella M,
|
||
Putotto C,
|
||
Marino B,
|
||
Pasquini M,
|
||
Biondi M,
|
||
Colonnese C,
|
||
Di Fabio F</span><br />
|
||
<span class="medgenPMjournal">Riv Psichiatr</span>
|
||
2023 Jan-Feb;58(1):10-20.
|
||
doi: 10.1708/3964.39426.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36715578" target="_blank">36715578</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31214731">Surgical Outcomes in Syndromic Tetralogy of Fallot: A Systematic Review and Evidence Quality Assessment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Athanasiadis DI,
|
||
Mylonas KS,
|
||
Kasparian K,
|
||
Ziogas IA,
|
||
Vlachopoulou D,
|
||
Sfyridis PG,
|
||
Schizas D,
|
||
Spartalis E,
|
||
Nikiteas N,
|
||
Hemmati P,
|
||
Kalangos A,
|
||
Avgerinos DV</span><br />
|
||
<span class="medgenPMjournal">Pediatr Cardiol</span>
|
||
2019 Aug;40(6):1105-1112.
|
||
Epub 2019 Jun 18
|
||
doi: 10.1007/s00246-019-02133-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31214731" target="_blank">31214731</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30542204">A somatic activating NRAS variant associated with kaposiform lymphangiomatosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barclay SF,
|
||
Inman KW,
|
||
Luks VL,
|
||
McIntyre JB,
|
||
Al-Ibraheemi A,
|
||
Church AJ,
|
||
Perez-Atayde AR,
|
||
Mangray S,
|
||
Jeng M,
|
||
Kreimer SR,
|
||
Walker L,
|
||
Fishman SJ,
|
||
Alomari AI,
|
||
Chaudry G,
|
||
Trenor Iii CC,
|
||
Adams D,
|
||
Kozakewich HPW,
|
||
Kurek KC</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2019 Jul;21(7):1517-1524.
|
||
Epub 2018 Dec 13
|
||
doi: 10.1038/s41436-018-0390-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30542204" target="_blank">30542204</a><a href="/pmc/articles/PMC6565516" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22777173">Infantile hypertrophic pyloric stenosis--genetics and syndromes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Peeters B,
|
||
Benninga MA,
|
||
Hennekam RC</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Gastroenterol Hepatol</span>
|
||
2012 Nov;9(11):646-60.
|
||
Epub 2012 Jul 10
|
||
doi: 10.1038/nrgastro.2012.133.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22777173" target="_blank">22777173</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18755723">T cell immunodeficiency.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Edgar JD</span><br />
|
||
<span class="medgenPMjournal">J Clin Pathol</span>
|
||
2008 Sep;61(9):988-93.
|
||
doi: 10.1136/jcp.2007.051144.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18755723" target="_blank">18755723</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lymphatic%20malformation%2011%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (436)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32022400">Congenital heart defects in Noonan syndrome: Diagnosis, management, and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Linglart L,
|
||
Gelb BD</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet C Semin Med Genet</span>
|
||
2020 Mar;184(1):73-80.
|
||
Epub 2020 Feb 5
|
||
doi: 10.1002/ajmg.c.31765.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32022400" target="_blank">32022400</a><a href="/pmc/articles/PMC7682536" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25689927">CHARGE syndrome: a review of the immunological aspects.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wong MT,
|
||
Schölvinck EH,
|
||
Lambeck AJ,
|
||
van Ravenswaaij-Arts CM</span><br />
|
||
<span class="medgenPMjournal">Eur J Hum Genet</span>
|
||
2015 Nov;23(11):1451-9.
|
||
Epub 2015 Feb 18
|
||
doi: 10.1038/ejhg.2015.7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25689927" target="_blank">25689927</a><a href="/pmc/articles/PMC4613462" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25123976">Central 22q11.2 deletions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rump P,
|
||
de Leeuw N,
|
||
van Essen AJ,
|
||
Verschuuren-Bemelmans CC,
|
||
Veenstra-Knol HE,
|
||
Swinkels ME,
|
||
Oostdijk W,
|
||
Ruivenkamp C,
|
||
Reardon W,
|
||
de Munnik S,
|
||
Ruiter M,
|
||
Frumkin A,
|
||
Lev D,
|
||
Evers C,
|
||
Sikkema-Raddatz B,
|
||
Dijkhuizen T,
|
||
van Ravenswaaij-Arts CM</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet A</span>
|
||
2014 Nov;164A(11):2707-23.
|
||
Epub 2014 Aug 14
|
||
doi: 10.1002/ajmg.a.36711.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25123976" target="_blank">25123976</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22857718">Pediatric neck masses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Goins MR,
|
||
Beasley MS</span><br />
|
||
<span class="medgenPMjournal">Oral Maxillofac Surg Clin North Am</span>
|
||
2012 Aug;24(3):457-68.
|
||
doi: 10.1016/j.coms.2012.05.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22857718" target="_blank">22857718</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18755723">T cell immunodeficiency.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Edgar JD</span><br />
|
||
<span class="medgenPMjournal">J Clin Pathol</span>
|
||
2008 Sep;61(9):988-93.
|
||
doi: 10.1136/jcp.2007.051144.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18755723" target="_blank">18755723</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lymphatic%20malformation%2011%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (433)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36044195">Treatment With Topical Sirolimus for Recurrent Lymphatic Malformation of the External Urethral Meatus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yonekura S,
|
||
Komori T,
|
||
Ishida Y,
|
||
Kogame T,
|
||
Kabashima K</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2022 Nov 1;158(11):1331-1332.
|
||
doi: 10.1001/jamadermatol.2022.2793.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36044195" target="_blank">36044195</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34524406">Sirolimus (Rapamycin) for Slow-Flow Malformations in Children: The Observational-Phase Randomized Clinical PERFORMUS Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maruani A,
|
||
Tavernier E,
|
||
Boccara O,
|
||
Mazereeuw-Hautier J,
|
||
Leducq S,
|
||
Bessis D,
|
||
Guibaud L,
|
||
Vabres P,
|
||
Carmignac V,
|
||
Mallet S,
|
||
Barbarot S,
|
||
Chiaverini C,
|
||
Droitcourt C,
|
||
Bursztejn AC,
|
||
Lengellé C,
|
||
Woillard JB,
|
||
Herbreteau D,
|
||
Le Touze A,
|
||
Joly A,
|
||
Léauté-Labrèze C,
|
||
Powell J,
|
||
Bourgoin H,
|
||
Gissot V,
|
||
Giraudeau B,
|
||
Morel B</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2021 Nov 1;157(11):1289-1298.
|
||
doi: 10.1001/jamadermatol.2021.3459.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34524406" target="_blank">34524406</a><a href="/pmc/articles/PMC8444064" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21742796">Normalization of the vasculature for treatment of cancer and other diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Goel S,
|
||
Duda DG,
|
||
Xu L,
|
||
Munn LL,
|
||
Boucher Y,
|
||
Fukumura D,
|
||
Jain RK</span><br />
|
||
<span class="medgenPMjournal">Physiol Rev</span>
|
||
2011 Jul;91(3):1071-121.
|
||
doi: 10.1152/physrev.00038.2010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21742796" target="_blank">21742796</a><a href="/pmc/articles/PMC3258432" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18755723">T cell immunodeficiency.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Edgar JD</span><br />
|
||
<span class="medgenPMjournal">J Clin Pathol</span>
|
||
2008 Sep;61(9):988-93.
|
||
doi: 10.1136/jcp.2007.051144.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18755723" target="_blank">18755723</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1812129">Animal models for human craniofacial malformations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Johnston MC,
|
||
Bronsky PT</span><br />
|
||
<span class="medgenPMjournal">J Craniofac Genet Dev Biol</span>
|
||
1991 Oct-Dec;11(4):277-91.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1812129" target="_blank">1812129</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lymphatic%20malformation%2011%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (163)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32842603">Consequences of 22q11.2 Microdeletion on the Genome, Individual and Population Levels.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karbarz M</span><br />
|
||
<span class="medgenPMjournal">Genes (Basel)</span>
|
||
2020 Aug 22;11(9)
|
||
doi: 10.3390/genes11090977.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32842603" target="_blank">32842603</a><a href="/pmc/articles/PMC7563277" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32022400">Congenital heart defects in Noonan syndrome: Diagnosis, management, and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Linglart L,
|
||
Gelb BD</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet C Semin Med Genet</span>
|
||
2020 Mar;184(1):73-80.
|
||
Epub 2020 Feb 5
|
||
doi: 10.1002/ajmg.c.31765.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32022400" target="_blank">32022400</a><a href="/pmc/articles/PMC7682536" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31742877">Mediastinal venolymphatic malformations mimicking thymic carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kang MK,
|
||
Kang DK,
|
||
Hwang YH,
|
||
Kim JY</span><br />
|
||
<span class="medgenPMjournal">Thorac Cancer</span>
|
||
2020 Jan;11(1):170-172.
|
||
Epub 2019 Nov 19
|
||
doi: 10.1111/1759-7714.13239.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31742877" target="_blank">31742877</a><a href="/pmc/articles/PMC6938752" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31214731">Surgical Outcomes in Syndromic Tetralogy of Fallot: A Systematic Review and Evidence Quality Assessment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Athanasiadis DI,
|
||
Mylonas KS,
|
||
Kasparian K,
|
||
Ziogas IA,
|
||
Vlachopoulou D,
|
||
Sfyridis PG,
|
||
Schizas D,
|
||
Spartalis E,
|
||
Nikiteas N,
|
||
Hemmati P,
|
||
Kalangos A,
|
||
Avgerinos DV</span><br />
|
||
<span class="medgenPMjournal">Pediatr Cardiol</span>
|
||
2019 Aug;40(6):1105-1112.
|
||
Epub 2019 Jun 18
|
||
doi: 10.1007/s00246-019-02133-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31214731" target="_blank">31214731</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21753696">Benign epithelial inclusions in axillary lymph nodes: report of 18 cases and review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fellegara G,
|
||
Carcangiu ML,
|
||
Rosai J</span><br />
|
||
<span class="medgenPMjournal">Am J Surg Pathol</span>
|
||
2011 Aug;35(8):1123-33.
|
||
doi: 10.1097/PAS.0b013e3182237985.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21753696" target="_blank">21753696</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lymphatic%20malformation%2011%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (196)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38608674">A regulatory variant impacting TBX1 expression contributes to basicranial morphology in Homo sapiens.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Funato N,
|
||
Heliövaara A,
|
||
Boeckx C</span><br />
|
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<span class="medgenPMjournal">Am J Hum Genet</span>
|
||
2024 May 2;111(5):939-953.
|
||
Epub 2024 Apr 11
|
||
doi: 10.1016/j.ajhg.2024.03.012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38608674" target="_blank">38608674</a><a href="/pmc/articles/PMC11080286" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37997544">Distinct neurocognitive profiles and clinical phenotypes associated with copy number variation at the 22q11.2 locus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Hora KP,
|
||
Kushan-Wells L,
|
||
Schleifer CH,
|
||
Cruz S,
|
||
Hoftman GD,
|
||
Jalbrzikowski M,
|
||
Gur RE,
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||
Gur RC,
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Bearden CE</span><br />
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<span class="medgenPMjournal">Autism Res</span>
|
||
2023 Dec;16(12):2247-2262.
|
||
Epub 2023 Nov 23
|
||
doi: 10.1002/aur.3049.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37997544" target="_blank">37997544</a><a href="/pmc/articles/PMC10872774" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36715578">Similar grey matter abnormalities in 22q11.2DS and chronic schizophrenia: a voxel-based morphometry study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Frascarelli M,
|
||
Accinni T,
|
||
Buzzanca A,
|
||
Di Bonaventura C,
|
||
Fanella M,
|
||
Putotto C,
|
||
Marino B,
|
||
Pasquini M,
|
||
Biondi M,
|
||
Colonnese C,
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||
Di Fabio F</span><br />
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||
<span class="medgenPMjournal">Riv Psichiatr</span>
|
||
2023 Jan-Feb;58(1):10-20.
|
||
doi: 10.1708/3964.39426.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36715578" target="_blank">36715578</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36360275">Adult Height, 22q11.2 Deletion Extent, and Short Stature in 22q11.2 Deletion Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Heung T,
|
||
Conroy B,
|
||
Malecki S,
|
||
Ha J,
|
||
Boot E,
|
||
Corral M,
|
||
Bassett AS</span><br />
|
||
<span class="medgenPMjournal">Genes (Basel)</span>
|
||
2022 Nov 5;13(11)
|
||
doi: 10.3390/genes13112038.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36360275" target="_blank">36360275</a><a href="/pmc/articles/PMC9690747" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34524406">Sirolimus (Rapamycin) for Slow-Flow Malformations in Children: The Observational-Phase Randomized Clinical PERFORMUS Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maruani A,
|
||
Tavernier E,
|
||
Boccara O,
|
||
Mazereeuw-Hautier J,
|
||
Leducq S,
|
||
Bessis D,
|
||
Guibaud L,
|
||
Vabres P,
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||
Carmignac V,
|
||
Mallet S,
|
||
Barbarot S,
|
||
Chiaverini C,
|
||
Droitcourt C,
|
||
Bursztejn AC,
|
||
Lengellé C,
|
||
Woillard JB,
|
||
Herbreteau D,
|
||
Le Touze A,
|
||
Joly A,
|
||
Léauté-Labrèze C,
|
||
Powell J,
|
||
Bourgoin H,
|
||
Gissot V,
|
||
Giraudeau B,
|
||
Morel B</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2021 Nov 1;157(11):1289-1298.
|
||
doi: 10.1001/jamadermatol.2021.3459.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34524406" target="_blank">34524406</a><a href="/pmc/articles/PMC8444064" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lymphatic%20malformation%2011%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (249)</a></div></div>
|
||
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|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/39248487">Fetal Cystic Lymphatic Malformations: Systematic Review on Pregnancy and Neonatal Outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nzelu D,
|
||
Panayotidis I,
|
||
Smith GD,
|
||
Pandya P</span><br />
|
||
<span class="medgenPMjournal">J Ultrasound Med</span>
|
||
2024 Dec;43(12):2327-2337.
|
||
Epub 2024 Sep 9
|
||
doi: 10.1002/jum.16566.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39248487" target="_blank">39248487</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37812168">Sirolimus for Pediatric Cervicofacial Lymphatic Malformation: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kamhieh Y,
|
||
Mitra R,
|
||
Burnett T,
|
||
Jones H,
|
||
Roblin G,
|
||
Hall A</span><br />
|
||
<span class="medgenPMjournal">Laryngoscope</span>
|
||
2024 May;134(5):2038-2047.
|
||
Epub 2023 Oct 9
|
||
doi: 10.1002/lary.31091.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37812168" target="_blank">37812168</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33890897">Surgical Treatment of Peripheral Vascular Malformations: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lokhorst MM,
|
||
Jolink F,
|
||
Horbach SER,
|
||
Spuls PI,
|
||
van der Horst CMAM</span><br />
|
||
<span class="medgenPMjournal">Plast Reconstr Surg</span>
|
||
2021 May 1;147(5):1149-1161.
|
||
doi: 10.1097/PRS.0000000000007837.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33890897" target="_blank">33890897</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33053612">Tubal flushing for subfertility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang R,
|
||
Watson A,
|
||
Johnson N,
|
||
Cheung K,
|
||
Fitzgerald C,
|
||
Mol BWJ,
|
||
Mohiyiddeen L</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2020 Oct 15;10(10):CD003718.
|
||
doi: 10.1002/14651858.CD003718.pub5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33053612" target="_blank">33053612</a><a href="/pmc/articles/PMC9508794" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26421368">Doxycycline sclerotherapy in children with head and neck lymphatic malformations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cheng J</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Surg</span>
|
||
2015 Dec;50(12):2143-6.
|
||
Epub 2015 Sep 4
|
||
doi: 10.1016/j.jpedsurg.2015.08.051.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26421368" target="_blank">26421368</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lymphatic%20malformation%2011%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (14)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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||
|
||
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|
||
|
||
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|
||
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|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
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|
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|
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=619401" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Lymphatic%20malformation%2011" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(lymphatic%20malformation%2011)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=600222" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=7075[geneid]" target="_blank">View TIE1 variations in ClinVar</a></li><li><a href="https://catalog.coriell.org/Search?q=619401" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/lymphatic_malformation_11" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Lymphatic%20malformation%2011" target="_blank">MedlinePlus</a></li></ul></div>
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<li>
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<a href="/pubmed/clinical?term=Lymphatic%20malformation%2011" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Lymphatic%20malformation%2011%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<h3>Related information</h3>
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<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=1784862" ref="log$=recordlinks">ClinVar</a>
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<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
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<div class="brieflinkpop offscreen_noflow">Related information in NCBI Gene</div>
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<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&from_uid=1784862" ref="log$=recordlinks">OMIM</a>
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<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
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<div class="brieflinkpop offscreen_noflow">OMIM records containing genes associated with phenotypes registered in MedGen</div>
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<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=1784862" ref="log$=recordlinks">PMC Articles</a>
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||
</li>
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||
<li>
|
||
<a class="text-white" href="https://www.nih.gov/">NIH</a>
|
||
</li>
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||
<li>
|
||
<a class="text-white" href="https://www.hhs.gov/">HHS</a>
|
||
</li>
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||
<li>
|
||
<a class="text-white" href="https://www.usa.gov/">USA.gov</a>
|
||
</li>
|
||
</ul>
|
||
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|
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||
</div>
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