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<meta name="keywords" content="C4749850, autosomal recessive early-onset ibd, autosomal recessive early-onset inflammatory bowel disease, disease or syndrome, il10 (interleukin 10) related early-onset inflammatory bowel disease, il10-related early-onset ibd, il10-related early-onset inflammatory bowel disease, immune dysregulation, inflammatory bowel disease, arthritis, recurrent infection syndrome, immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome, interleukin 10 related early-onset inflammatory bowel disease, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A rare immune dysregulation disease with immunodeficiency and characteristics of severe, progressive infantile onset inflammatory bowel disease with pancolitis, perianal disease (ulceration, fistulae), recurrent respiratory, genitourinary and cutaneous infections, arthritis and a high risk of B-cell lymphoma." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=1661450
|
||
ConceptID=C4749850
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1661450</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4749850</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Autosomal recessive early-onset inflammatory bowel disease</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>IL10-related early-onset inflammatory bowel disease (771333006); Immune dysregulation, inflammatory bowel disease, arthritis, recurrent infection syndrome (771333006); Interleukin 10 related early-onset inflammatory bowel disease (771333006); IL10 (interleukin 10) related early-onset inflammatory bowel disease (771333006)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_141025"><div><strong>Autosomal recessive inheritance</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>141025</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0441748</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Intellectual Product</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in individuals with two pathogenic alleles, either homozygotes (two copies of the same mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele).</div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_141025" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive inheritance</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0016542" target="_blank">MONDO:0016542</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=238569">ORPHA238569</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A rare immune dysregulation disease with immunodeficiency and characteristics of severe, progressive infantile onset inflammatory bowel disease with pancolitis, perianal disease (ulceration, fistulae), recurrent respiratory, genitourinary and cutaneous infections, arthritis and a high risk of B-cell lymphoma. [from <a title="US Edition of SNOMED CT" href="http://www.nlm.nih.gov/research/umls/Snomed/us_edition.html" class="defSource" target="_blank">SNOMEDCT_US</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1842887" ref="tree=MeSH" title="MedGen record for Immune dysregulation with inflammatory bowel disease">Immune dysregulation with inflammatory bowel disease</a></span><ul><li><span class="matched_ds">Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome</span></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33903147">British Society of Gastroenterology guidelines on the management of irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vasant DH,
|
||
Paine PA,
|
||
Black CJ,
|
||
Houghton LA,
|
||
Everitt HA,
|
||
Corsetti M,
|
||
Agrawal A,
|
||
Aziz I,
|
||
Farmer AD,
|
||
Eugenicos MP,
|
||
Moss-Morris R,
|
||
Yiannakou Y,
|
||
Ford AC</span><br />
|
||
<span class="medgenPMjournal">Gut</span>
|
||
2021 Jul;70(7):1214-1240.
|
||
Epub 2021 Apr 26
|
||
doi: 10.1136/gutjnl-2021-324598.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33903147" target="_blank">33903147</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31893959">An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aziz I,
|
||
Whitehead WE,
|
||
Palsson OS,
|
||
Törnblom H,
|
||
Simrén M</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Gastroenterol Hepatol</span>
|
||
2020 Jan;14(1):39-46.
|
||
Epub 2020 Jan 2
|
||
doi: 10.1080/17474124.2020.1708718.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31893959" target="_blank">31893959</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28212760">Psoriasis and comorbid diseases: Implications for management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Takeshita J,
|
||
Grewal S,
|
||
Langan SM,
|
||
Mehta NN,
|
||
Ogdie A,
|
||
Van Voorhees AS,
|
||
Gelfand JM</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2017 Mar;76(3):393-403.
|
||
doi: 10.1016/j.jaad.2016.07.065.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28212760" target="_blank">28212760</a><a href="/pmc/articles/PMC5839668" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(immune%20dysregulation-inflammatory%20bowel%20disease-arthritis-recurrent%20infections%20syndrome)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (66)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35870984">Neutrophilic dermatoses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Delaleu J,
|
||
Lepelletier C,
|
||
Calugareanu A,
|
||
De Masson A,
|
||
Charvet E,
|
||
Petit A,
|
||
Giurgea I,
|
||
Amselem S,
|
||
Karabina S,
|
||
Jachiet M,
|
||
Mahevas T,
|
||
Ram-Wolff C,
|
||
Vignon-Pennamen MD,
|
||
Bagot M,
|
||
Battistella M,
|
||
Bouaziz JD</span><br />
|
||
<span class="medgenPMjournal">Rev Med Interne</span>
|
||
2022 Dec;43(12):727-738.
|
||
Epub 2022 Jul 20
|
||
doi: 10.1016/j.revmed.2022.06.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35870984" target="_blank">35870984</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33049223">Irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ford AC,
|
||
Sperber AD,
|
||
Corsetti M,
|
||
Camilleri M</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2020 Nov 21;396(10263):1675-1688.
|
||
Epub 2020 Oct 10
|
||
doi: 10.1016/S0140-6736(20)31548-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33049223" target="_blank">33049223</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32821067">Secondary causes of inflammatory bowel diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghouri YA,
|
||
Tahan V,
|
||
Shen B</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2020 Jul 28;26(28):3998-4017.
|
||
doi: 10.3748/wjg.v26.i28.3998.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32821067" target="_blank">32821067</a><a href="/pmc/articles/PMC7403802" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30741841">Thirty Years of Lactobacillus rhamnosus GG: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Capurso L</span><br />
|
||
<span class="medgenPMjournal">J Clin Gastroenterol</span>
|
||
2019 Mar;53 Suppl 1:S1-S41.
|
||
doi: 10.1097/MCG.0000000000001170.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30741841" target="_blank">30741841</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28404070">Pathophysiology of irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Holtmann GJ,
|
||
Ford AC,
|
||
Talley NJ</span><br />
|
||
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
|
||
2016 Oct;1(2):133-146.
|
||
Epub 2016 Sep 8
|
||
doi: 10.1016/S2468-1253(16)30023-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28404070" target="_blank">28404070</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Immune%20dysregulation-inflammatory%20bowel%20disease-arthritis-recurrent%20infections%20syndrome%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (362)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35870984">Neutrophilic dermatoses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Delaleu J,
|
||
Lepelletier C,
|
||
Calugareanu A,
|
||
De Masson A,
|
||
Charvet E,
|
||
Petit A,
|
||
Giurgea I,
|
||
Amselem S,
|
||
Karabina S,
|
||
Jachiet M,
|
||
Mahevas T,
|
||
Ram-Wolff C,
|
||
Vignon-Pennamen MD,
|
||
Bagot M,
|
||
Battistella M,
|
||
Bouaziz JD</span><br />
|
||
<span class="medgenPMjournal">Rev Med Interne</span>
|
||
2022 Dec;43(12):727-738.
|
||
Epub 2022 Jul 20
|
||
doi: 10.1016/j.revmed.2022.06.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35870984" target="_blank">35870984</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33049223">Irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ford AC,
|
||
Sperber AD,
|
||
Corsetti M,
|
||
Camilleri M</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2020 Nov 21;396(10263):1675-1688.
|
||
Epub 2020 Oct 10
|
||
doi: 10.1016/S0140-6736(20)31548-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33049223" target="_blank">33049223</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31893959">An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aziz I,
|
||
Whitehead WE,
|
||
Palsson OS,
|
||
Törnblom H,
|
||
Simrén M</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Gastroenterol Hepatol</span>
|
||
2020 Jan;14(1):39-46.
|
||
Epub 2020 Jan 2
|
||
doi: 10.1080/17474124.2020.1708718.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31893959" target="_blank">31893959</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28404070">Pathophysiology of irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Holtmann GJ,
|
||
Ford AC,
|
||
Talley NJ</span><br />
|
||
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
|
||
2016 Oct;1(2):133-146.
|
||
Epub 2016 Sep 8
|
||
doi: 10.1016/S2468-1253(16)30023-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28404070" target="_blank">28404070</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22917171">Diarrhea in the immunocompromised patient.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krones E,
|
||
Högenauer C</span><br />
|
||
<span class="medgenPMjournal">Gastroenterol Clin North Am</span>
|
||
2012 Sep;41(3):677-701.
|
||
Epub 2012 Jul 4
|
||
doi: 10.1016/j.gtc.2012.06.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22917171" target="_blank">22917171</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Immune%20dysregulation-inflammatory%20bowel%20disease-arthritis-recurrent%20infections%20syndrome%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (320)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33049223">Irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ford AC,
|
||
Sperber AD,
|
||
Corsetti M,
|
||
Camilleri M</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2020 Nov 21;396(10263):1675-1688.
|
||
Epub 2020 Oct 10
|
||
doi: 10.1016/S0140-6736(20)31548-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33049223" target="_blank">33049223</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31893959">An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aziz I,
|
||
Whitehead WE,
|
||
Palsson OS,
|
||
Törnblom H,
|
||
Simrén M</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Gastroenterol Hepatol</span>
|
||
2020 Jan;14(1):39-46.
|
||
Epub 2020 Jan 2
|
||
doi: 10.1080/17474124.2020.1708718.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31893959" target="_blank">31893959</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30741841">Thirty Years of Lactobacillus rhamnosus GG: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Capurso L</span><br />
|
||
<span class="medgenPMjournal">J Clin Gastroenterol</span>
|
||
2019 Mar;53 Suppl 1:S1-S41.
|
||
doi: 10.1097/MCG.0000000000001170.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30741841" target="_blank">30741841</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22917171">Diarrhea in the immunocompromised patient.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krones E,
|
||
Högenauer C</span><br />
|
||
<span class="medgenPMjournal">Gastroenterol Clin North Am</span>
|
||
2012 Sep;41(3):677-701.
|
||
Epub 2012 Jul 4
|
||
doi: 10.1016/j.gtc.2012.06.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22917171" target="_blank">22917171</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20208051">Probiotics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Williams NT</span><br />
|
||
<span class="medgenPMjournal">Am J Health Syst Pharm</span>
|
||
2010 Mar 15;67(6):449-58.
|
||
doi: 10.2146/ajhp090168.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20208051" target="_blank">20208051</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Immune%20dysregulation-inflammatory%20bowel%20disease-arthritis-recurrent%20infections%20syndrome%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (334)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36464877">Post-COVID-19 Gastro-Intestinal Disturbances.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Scarpellini E,
|
||
Tack J</span><br />
|
||
<span class="medgenPMjournal">Rev Recent Clin Trials</span>
|
||
2023;18(1):34-40.
|
||
doi: 10.2174/1574887118666221201104833.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36464877" target="_blank">36464877</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35240330">Efficacy and Acceptability of Dietary Therapies in Non-Constipated Irritable Bowel Syndrome: A Randomized Trial of Traditional Dietary Advice, the Low FODMAP Diet, and the Gluten-Free Diet.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rej A,
|
||
Sanders DS,
|
||
Shaw CC,
|
||
Buckle R,
|
||
Trott N,
|
||
Agrawal A,
|
||
Aziz I</span><br />
|
||
<span class="medgenPMjournal">Clin Gastroenterol Hepatol</span>
|
||
2022 Dec;20(12):2876-2887.e15.
|
||
Epub 2022 Feb 28
|
||
doi: 10.1016/j.cgh.2022.02.045.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35240330" target="_blank">35240330</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34358486">Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-blind, placebo-controlled trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wauters L,
|
||
Slaets H,
|
||
De Paepe K,
|
||
Ceulemans M,
|
||
Wetzels S,
|
||
Geboers K,
|
||
Toth J,
|
||
Thys W,
|
||
Dybajlo R,
|
||
Walgraeve D,
|
||
Biessen E,
|
||
Verbeke K,
|
||
Tack J,
|
||
Van de Wiele T,
|
||
Hellings N,
|
||
Vanuytsel T</span><br />
|
||
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
|
||
2021 Oct;6(10):784-792.
|
||
Epub 2021 Aug 3
|
||
doi: 10.1016/S2468-1253(21)00226-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34358486" target="_blank">34358486</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33049223">Irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ford AC,
|
||
Sperber AD,
|
||
Corsetti M,
|
||
Camilleri M</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2020 Nov 21;396(10263):1675-1688.
|
||
Epub 2020 Oct 10
|
||
doi: 10.1016/S0140-6736(20)31548-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33049223" target="_blank">33049223</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28477696">Whipple's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">El-Abassi R,
|
||
Soliman MY,
|
||
Williams F,
|
||
England JD</span><br />
|
||
<span class="medgenPMjournal">J Neurol Sci</span>
|
||
2017 Jun 15;377:197-206.
|
||
Epub 2017 Feb 16
|
||
doi: 10.1016/j.jns.2017.01.048.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28477696" target="_blank">28477696</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Immune%20dysregulation-inflammatory%20bowel%20disease-arthritis-recurrent%20infections%20syndrome%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (178)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38350464">Bifidobacterium adolescentis - a beneficial microbe.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leser T,
|
||
Baker A</span><br />
|
||
<span class="medgenPMjournal">Benef Microbes</span>
|
||
2023 Nov 27;14(6):525-551.
|
||
doi: 10.1163/18762891-20230030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38350464" target="_blank">38350464</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35240330">Efficacy and Acceptability of Dietary Therapies in Non-Constipated Irritable Bowel Syndrome: A Randomized Trial of Traditional Dietary Advice, the Low FODMAP Diet, and the Gluten-Free Diet.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rej A,
|
||
Sanders DS,
|
||
Shaw CC,
|
||
Buckle R,
|
||
Trott N,
|
||
Agrawal A,
|
||
Aziz I</span><br />
|
||
<span class="medgenPMjournal">Clin Gastroenterol Hepatol</span>
|
||
2022 Dec;20(12):2876-2887.e15.
|
||
Epub 2022 Feb 28
|
||
doi: 10.1016/j.cgh.2022.02.045.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35240330" target="_blank">35240330</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33752754">Direct impact of commonly used dietary emulsifiers on human gut microbiota.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Naimi S,
|
||
Viennois E,
|
||
Gewirtz AT,
|
||
Chassaing B</span><br />
|
||
<span class="medgenPMjournal">Microbiome</span>
|
||
2021 Mar 22;9(1):66.
|
||
doi: 10.1186/s40168-020-00996-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33752754" target="_blank">33752754</a><a href="/pmc/articles/PMC7986288" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32460374">Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nguyen TV,
|
||
Damiani G,
|
||
Orenstein LAV,
|
||
Hamzavi I,
|
||
Jemec GB</span><br />
|
||
<span class="medgenPMjournal">J Eur Acad Dermatol Venereol</span>
|
||
2021 Jan;35(1):50-61.
|
||
Epub 2020 Jul 16
|
||
doi: 10.1111/jdv.16677.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32460374" target="_blank">32460374</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30655633">Multidisciplinary approach to prostatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Magri V,
|
||
Boltri M,
|
||
Cai T,
|
||
Colombo R,
|
||
Cuzzocrea S,
|
||
De Visschere P,
|
||
Giuberti R,
|
||
Granatieri CM,
|
||
Latino MA,
|
||
Larganà G,
|
||
Leli C,
|
||
Maierna G,
|
||
Marchese V,
|
||
Massa E,
|
||
Matteelli A,
|
||
Montanari E,
|
||
Morgia G,
|
||
Naber KG,
|
||
Papadouli V,
|
||
Perletti G,
|
||
Rekleiti N,
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||
Russo GI,
|
||
Sensini A,
|
||
Stamatiou K,
|
||
Trinchieri A,
|
||
Wagenlehner FME</span><br />
|
||
<span class="medgenPMjournal">Arch Ital Urol Androl</span>
|
||
2019 Jan 18;90(4):227-248.
|
||
doi: 10.4081/aiua.2018.4.227.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30655633" target="_blank">30655633</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Immune%20dysregulation-inflammatory%20bowel%20disease-arthritis-recurrent%20infections%20syndrome%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (226)</a></div></div>
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||
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|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/34974509">SARS-CoV-2 vaccination in patients with inflammatory bowel disease: A systemic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sung KY,
|
||
Chang TE,
|
||
Wang YP,
|
||
Lin CC,
|
||
Chang CY,
|
||
Hou MC,
|
||
Lu CL</span><br />
|
||
<span class="medgenPMjournal">J Chin Med Assoc</span>
|
||
2022 Apr 1;85(4):421-430.
|
||
doi: 10.1097/JCMA.0000000000000682.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34974509" target="_blank">34974509</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32056910">Feeling down? A systematic review of the gut microbiota in anxiety/depression and irritable bowel syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Simpson CA,
|
||
Mu A,
|
||
Haslam N,
|
||
Schwartz OS,
|
||
Simmons JG</span><br />
|
||
<span class="medgenPMjournal">J Affect Disord</span>
|
||
2020 Apr 1;266:429-446.
|
||
Epub 2020 Jan 22
|
||
doi: 10.1016/j.jad.2020.01.124.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32056910" target="_blank">32056910</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30619323">Hidradenitis Suppurativa: A Systematic Review Integrating Inflammatory Pathways Into a Cohesive Pathogenic Model.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vossen ARJV,
|
||
van der Zee HH,
|
||
Prens EP</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2018;9:2965.
|
||
Epub 2018 Dec 14
|
||
doi: 10.3389/fimmu.2018.02965.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30619323" target="_blank">30619323</a><a href="/pmc/articles/PMC6302105" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29804008">Chronic sequelae and severe complications of norovirus infection: A systematic review of literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petrignani M,
|
||
Verhoef L,
|
||
de Graaf M,
|
||
Richardus JH,
|
||
Koopmans M</span><br />
|
||
<span class="medgenPMjournal">J Clin Virol</span>
|
||
2018 Aug;105:1-10.
|
||
Epub 2018 May 24
|
||
doi: 10.1016/j.jcv.2018.05.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29804008" target="_blank">29804008</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28233293">Pediatric pyoderma gangrenosum: a systematic review and update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kechichian E,
|
||
Haber R,
|
||
Mourad N,
|
||
El Khoury R,
|
||
Jabbour S,
|
||
Tomb R</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2017 May;56(5):486-495.
|
||
Epub 2017 Feb 23
|
||
doi: 10.1111/ijd.13584.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28233293" target="_blank">28233293</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Immune%20dysregulation-inflammatory%20bowel%20disease-arthritis-recurrent%20infections%20syndrome%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10)</a></div></div>
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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