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<meta name="keywords" content="C4022749, abnormal brainstem mri signal intensity, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A deviation from normal signal on magnetic resonance imaging (MRI) of the brainstem." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=868355
|
||
ConceptID=C4022749
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Abnormal brainstem MRI signal intensity</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>868355</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4022749</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0012747">HP:0012747</a></td></tr>
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|
||
<div class="portlet_content ln">A deviation from normal signal on magnetic resonance imaging (MRI) of the brainstem. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Abnormal brainstem MRI signal intensity</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868416" ref="tree=MeSH" title="MedGen record for Abnormal nervous system morphology">Abnormal nervous system morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892343" ref="tree=MeSH" title="MedGen record for Morphological central nervous system abnormality">Morphological central nervous system abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/866738" ref="tree=MeSH" title="MedGen record for Abnormal brain morphology">Abnormal brain morphology</a></span><ul><li><span class="TLline"><a href="/medgen/342543" ref="tree=MeSH" title="MedGen record for Abnormal brainstem morphology">Abnormal brainstem morphology</a></span><ul><li><span class="matched_ds">Abnormal brainstem MRI signal intensity</span><ul><li><span class="TLline"><a href="/medgen/1864060" ref="tree=MeSH" title="MedGen record for Focal T1 hyperintense brainstem lesion">Focal T1 hyperintense brainstem lesion</a></span></li><li><span class="TLline"><a href="/medgen/868354" ref="tree=MeSH" title="MedGen record for Focal T2 hyperintense brainstem lesion">Focal T2 hyperintense brainstem lesion</a></span></li><li><span class="TLline"><a href="/medgen/868353" ref="tree=MeSH" title="MedGen record for Focal T2 hypointense brainstem lesion">Focal T2 hypointense brainstem lesion</a></span></li><li><span class="TLline"><a href="/medgen/868352" ref="tree=MeSH" title="MedGen record for T2 hypointense brainstem">T2 hypointense brainstem</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_1748867"><div><strong>Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1748867</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5399977</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Mitochondrial complex IV deficiency nuclear type 2 (MC4DN2) is an autosomal recessive multisystem metabolic disorder characterized by the onset of symptoms at birth or in the first weeks or months of life. Affected individuals have severe hypotonia, often associated with feeding difficulties and respiratory insufficiency necessitating tube feeding and mechanical ventilation. The vast majority of patients develop hypertrophic cardiomyopathy in the first days or weeks of life, which usually leads to death in infancy or early childhood. Patients also show neurologic abnormalities, including developmental delay, nystagmus, fasciculations, dystonia, EEG changes, and brain imaging abnormalities compatible with a diagnosis of Leigh syndrome (see 256000). There may also be evidence of systemic involvement with hepatomegaly and myopathy, although neurogenic muscle atrophy is more common and may resemble spinal muscular atrophy type I (SMA1; 253300). Serum lactate is increased, and laboratory studies show decreased mitochondrial complex IV protein and activity levels in various tissues, including heart and skeletal muscle. Most patients die in infancy of cardiorespiratory failure (summary by Papadopoulou et al., 1999). For a discussion of genetic heterogeneity of mitochondrial complex IV (cytochrome c oxidase) deficiency, see 220110.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1748867">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1748867" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/24506839">Neuro-behçet's disease in South Korea: clinical characteristics and treatment response.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yoon DL,
|
||
Kim YJ,
|
||
Koo BS,
|
||
Kim YG,
|
||
Lee CK,
|
||
Yoo B</span><br />
|
||
<span class="medgenPMjournal">Int J Rheum Dis</span>
|
||
2014 May;17(4):453-8.
|
||
Epub 2014 Feb 8
|
||
doi: 10.1111/1756-185X.12265.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24506839" target="_blank">24506839</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18071981">The Children's Cancer and Leukaemia Group guidelines for the diagnosis and management of dysembryoplastic neuroepithelial tumours.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Brien DF,
|
||
Farrell M,
|
||
Delanty N,
|
||
Traunecker H,
|
||
Perrin R,
|
||
Smyth MD,
|
||
Park TS;
|
||
Children's Cancer and Leukaemia Group</span><br />
|
||
<span class="medgenPMjournal">Br J Neurosurg</span>
|
||
2007 Dec;21(6):539-49.
|
||
doi: 10.1080/02688690701594817.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18071981" target="_blank">18071981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17618523">Fragile X-associated tremor/ataxia syndrome: clinical features, genetics, and testing guidelines.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Berry-Kravis E,
|
||
Abrams L,
|
||
Coffey SM,
|
||
Hall DA,
|
||
Greco C,
|
||
Gane LW,
|
||
Grigsby J,
|
||
Bourgeois JA,
|
||
Finucane B,
|
||
Jacquemont S,
|
||
Brunberg JA,
|
||
Zhang L,
|
||
Lin J,
|
||
Tassone F,
|
||
Hagerman PJ,
|
||
Hagerman RJ,
|
||
Leehey MA</span><br />
|
||
<span class="medgenPMjournal">Mov Disord</span>
|
||
2007 Oct 31;22(14):2018-30, quiz 2140.
|
||
doi: 10.1002/mds.21493.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17618523" target="_blank">17618523</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(abnormal%20brainstem%20mri%20signal%20intensity)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (5)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/23448452">Neurological complications of Anderson-Fabry disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tuttolomondo A,
|
||
Pecoraro R,
|
||
Simonetta I,
|
||
Miceli S,
|
||
Arnao V,
|
||
Licata G,
|
||
Pinto A</span><br />
|
||
<span class="medgenPMjournal">Curr Pharm Des</span>
|
||
2013;19(33):6014-30.
|
||
doi: 10.2174/13816128113199990387.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23448452" target="_blank">23448452</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16455079">MRI volumetric and intensity analysis of the cerebellum in Parkinson's disease patients infused with glial-derived neurotrophic factor (GDNF).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chebrolu H,
|
||
Slevin JT,
|
||
Gash DA,
|
||
Gerhardt GA,
|
||
Young B,
|
||
Given CA,
|
||
Smith CD</span><br />
|
||
<span class="medgenPMjournal">Exp Neurol</span>
|
||
2006 Apr;198(2):450-6.
|
||
Epub 2006 Feb 7
|
||
doi: 10.1016/j.expneurol.2005.12.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16455079" target="_blank">16455079</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12819838">Diffusion-weighted MR imaging of neuro-Behçet's disease: a case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hiwatashi A,
|
||
Garber T,
|
||
Moritani T,
|
||
Kinoshita T,
|
||
Westesson PL</span><br />
|
||
<span class="medgenPMjournal">Neuroradiology</span>
|
||
2003 Jul;45(7):468-71.
|
||
Epub 2003 Jun 18
|
||
doi: 10.1007/s00234-003-1000-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12819838" target="_blank">12819838</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2337012">Magnetic resonance imaging of the brain and brain-stem in elderly patients with dizziness.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Day JJ,
|
||
Freer CE,
|
||
Dixon AK,
|
||
Coni N,
|
||
Hall LD,
|
||
Sims C,
|
||
Gehlhaar EW</span><br />
|
||
<span class="medgenPMjournal">Age Ageing</span>
|
||
1990 Mar;19(2):144-50.
|
||
doi: 10.1093/ageing/19.2.144.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2337012" target="_blank">2337012</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3685341">Subcortical arteriosclerotic encephalopathy: brain stem findings with MR imaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Salomon A,
|
||
Yeates AE,
|
||
Burger PC,
|
||
Heinz ER</span><br />
|
||
<span class="medgenPMjournal">Radiology</span>
|
||
1987 Dec;165(3):625-9.
|
||
doi: 10.1148/radiology.165.3.3685341.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3685341" target="_blank">3685341</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20brainstem%20MRI%20signal%20intensity%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (100)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30620693">Adult Leukodystrophies: A Step-by-Step Diagnostic Approach.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Resende LL,
|
||
de Paiva ARB,
|
||
Kok F,
|
||
da Costa Leite C,
|
||
Lucato LT</span><br />
|
||
<span class="medgenPMjournal">Radiographics</span>
|
||
2019 Jan-Feb;39(1):153-168.
|
||
doi: 10.1148/rg.2019180081.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30620693" target="_blank">30620693</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24375007">Giant cerebellar cavernous malformation in 4-month-old boy. Case report and review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jurkiewicz E,
|
||
Marcinska B,
|
||
Malczyk K,
|
||
Grajkowska W,
|
||
Daszkiewicz P,
|
||
Roszkowski M</span><br />
|
||
<span class="medgenPMjournal">Neurol Neurochir Pol</span>
|
||
2013 Nov-Dec;47(6):596-600.
|
||
doi: 10.5114/ninp.2013.39078.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24375007" target="_blank">24375007</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21601052">Neuroimaging in rabies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Laothamatas J,
|
||
Sungkarat W,
|
||
Hemachudha T</span><br />
|
||
<span class="medgenPMjournal">Adv Virus Res</span>
|
||
2011;79:309-27.
|
||
doi: 10.1016/B978-0-12-387040-7.00014-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21601052" target="_blank">21601052</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17496795">Reduced signal of locus ceruleus in depression in quantitative neuromelanin magnetic resonance imaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shibata E,
|
||
Sasaki M,
|
||
Tohyama K,
|
||
Otsuka K,
|
||
Sakai A</span><br />
|
||
<span class="medgenPMjournal">Neuroreport</span>
|
||
2007 Mar 26;18(5):415-8.
|
||
doi: 10.1097/WNR.0b013e328058674a.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17496795" target="_blank">17496795</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9592791">Spinocerebellar ataxia type 6: MRI of three Japanese patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Satoh JI,
|
||
Tokumoto H,
|
||
Yukitake M,
|
||
Matsui M,
|
||
Matsuyama Z,
|
||
Kawakami H,
|
||
Nakamura S,
|
||
Kuroda Y</span><br />
|
||
<span class="medgenPMjournal">Neuroradiology</span>
|
||
1998 Apr;40(4):222-7.
|
||
doi: 10.1007/s002340050571.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9592791" target="_blank">9592791</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20brainstem%20MRI%20signal%20intensity%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (200)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/27798639">New Findings, Classification and Long-Term Follow-Up Study Based on MRI Characterization of Brainstem Encephalitis Induced by Enterovirus 71.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zeng H,
|
||
Wen F,
|
||
Huang W,
|
||
Gan Y,
|
||
Zeng W,
|
||
Chen R,
|
||
He Y,
|
||
Wang Y,
|
||
Liu Z,
|
||
Liang C,
|
||
Wong KK</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2016;11(10):e0162877.
|
||
Epub 2016 Oct 31
|
||
doi: 10.1371/journal.pone.0162877.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27798639" target="_blank">27798639</a><a href="/pmc/articles/PMC5087960" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26774704">The magnetic resonance imaging spectrum of Pelizaeus-Merzbacher disease: A multicenter study of 19 patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sumida K,
|
||
Inoue K,
|
||
Takanashi J,
|
||
Sasaki M,
|
||
Watanabe K,
|
||
Suzuki M,
|
||
Kurahashi H,
|
||
Omata T,
|
||
Tanaka M,
|
||
Yokochi K,
|
||
Iio J,
|
||
Iyoda K,
|
||
Kurokawa T,
|
||
Matsuo M,
|
||
Sato T,
|
||
Iwaki A,
|
||
Osaka H,
|
||
Kurosawa K,
|
||
Yamamoto T,
|
||
Matsumoto N,
|
||
Maikusa N,
|
||
Matsuda H,
|
||
Sato N</span><br />
|
||
<span class="medgenPMjournal">Brain Dev</span>
|
||
2016 Jun;38(6):571-80.
|
||
Epub 2016 Jan 13
|
||
doi: 10.1016/j.braindev.2015.12.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26774704" target="_blank">26774704</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21940698">Cerebellar gliomatosis in a toddler: case report of a challenging condition and review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chadarévian JP,
|
||
Legido A,
|
||
Halligan GE,
|
||
Faerber EN,
|
||
Piatt JH,
|
||
Morrissette JD,
|
||
Ara J,
|
||
Grant ML,
|
||
Katsetos CD</span><br />
|
||
<span class="medgenPMjournal">J Child Neurol</span>
|
||
2012 Apr;27(4):511-20.
|
||
Epub 2011 Sep 21
|
||
doi: 10.1177/0883073811419315.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21940698" target="_blank">21940698</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18202230">Substantia nigra MR imaging signal changes and cardiomyopathy following prenatal exposure to cocaine and heroin.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arnold R,
|
||
Johnson C,
|
||
McNulty B,
|
||
Gaisie G</span><br />
|
||
<span class="medgenPMjournal">AJNR Am J Neuroradiol</span>
|
||
2008 Apr;29(4):828-9.
|
||
Epub 2008 Jan 17
|
||
doi: 10.3174/ajnr.A0966.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18202230" target="_blank">18202230</a><a href="/pmc/articles/PMC7978184" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16455079">MRI volumetric and intensity analysis of the cerebellum in Parkinson's disease patients infused with glial-derived neurotrophic factor (GDNF).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chebrolu H,
|
||
Slevin JT,
|
||
Gash DA,
|
||
Gerhardt GA,
|
||
Young B,
|
||
Given CA,
|
||
Smith CD</span><br />
|
||
<span class="medgenPMjournal">Exp Neurol</span>
|
||
2006 Apr;198(2):450-6.
|
||
Epub 2006 Feb 7
|
||
doi: 10.1016/j.expneurol.2005.12.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16455079" target="_blank">16455079</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20brainstem%20MRI%20signal%20intensity%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (32)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/25466363">RYR1-related malignant hyperthermia with marked cerebellar involvement - a paradigm of heat-induced CNS injury?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Forrest KM,
|
||
Foulds N,
|
||
Millar JS,
|
||
Sutherland PD,
|
||
Pappachan VJ,
|
||
Holden S,
|
||
Mein R,
|
||
Hopkins PM,
|
||
Jungbluth H</span><br />
|
||
<span class="medgenPMjournal">Neuromuscul Disord</span>
|
||
2015 Feb;25(2):138-40.
|
||
Epub 2014 Oct 31
|
||
doi: 10.1016/j.nmd.2014.10.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25466363" target="_blank">25466363</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23448452">Neurological complications of Anderson-Fabry disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tuttolomondo A,
|
||
Pecoraro R,
|
||
Simonetta I,
|
||
Miceli S,
|
||
Arnao V,
|
||
Licata G,
|
||
Pinto A</span><br />
|
||
<span class="medgenPMjournal">Curr Pharm Des</span>
|
||
2013;19(33):6014-30.
|
||
doi: 10.2174/13816128113199990387.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23448452" target="_blank">23448452</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21601052">Neuroimaging in rabies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Laothamatas J,
|
||
Sungkarat W,
|
||
Hemachudha T</span><br />
|
||
<span class="medgenPMjournal">Adv Virus Res</span>
|
||
2011;79:309-27.
|
||
doi: 10.1016/B978-0-12-387040-7.00014-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21601052" target="_blank">21601052</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12819838">Diffusion-weighted MR imaging of neuro-Behçet's disease: a case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hiwatashi A,
|
||
Garber T,
|
||
Moritani T,
|
||
Kinoshita T,
|
||
Westesson PL</span><br />
|
||
<span class="medgenPMjournal">Neuroradiology</span>
|
||
2003 Jul;45(7):468-71.
|
||
Epub 2003 Jun 18
|
||
doi: 10.1007/s00234-003-1000-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12819838" target="_blank">12819838</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9380069">Action palatal tremor in a patient with primary intestinal lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gambardella A,
|
||
Zappia A,
|
||
Valentino P,
|
||
Aguglia U,
|
||
Fera F,
|
||
Pardatscher K,
|
||
Quattrone A</span><br />
|
||
<span class="medgenPMjournal">Mov Disord</span>
|
||
1997 Sep;12(5):794-7.
|
||
doi: 10.1002/mds.870120530.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9380069" target="_blank">9380069</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20brainstem%20MRI%20signal%20intensity%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (65)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33754827">Associations of Brain Atrophy and Cerebral Iron Accumulation at MRI with Clinical Severity in Wilson Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dusek P,
|
||
Lescinskij A,
|
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Ruzicka F,
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Sieger T,
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<span class="medgenPMjournal">Radiology</span>
|
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2021 Jun;299(3):662-672.
|
||
Epub 2021 Mar 23
|
||
doi: 10.1148/radiol.2021202846.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33754827" target="_blank">33754827</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30620693">Adult Leukodystrophies: A Step-by-Step Diagnostic Approach.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Resende LL,
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de Paiva ARB,
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Kok F,
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2019 Jan-Feb;39(1):153-168.
|
||
doi: 10.1148/rg.2019180081.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30620693" target="_blank">30620693</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15565345">MRI of the fetal posterior fossa.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Adamsbaum C,
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Moutard ML,
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André C,
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Merzoug V,
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Ferey S,
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Quéré MP,
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<span class="medgenPMjournal">Pediatr Radiol</span>
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2005 Feb;35(2):124-40.
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Epub 2004 Nov 23
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doi: 10.1007/s00247-004-1316-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15565345" target="_blank">15565345</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/9380069">Action palatal tremor in a patient with primary intestinal lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gambardella A,
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Zappia A,
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Valentino P,
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Aguglia U,
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Fera F,
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1997 Sep;12(5):794-7.
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|
||
<span class="bold">PMID: </span><a href="/pubmed/9380069" target="_blank">9380069</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/2215902">MR imaging of wallerian degeneration in the human brain stem after ictus.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Uchino A,
|
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|
||
<span class="bold">PMID: </span><a href="/pubmed/2215902" target="_blank">2215902</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20brainstem%20MRI%20signal%20intensity%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (67)</a></div></div>
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