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<meta name="keywords" content="C4022450, abnormal blood calcium concentration, abnormal blood calcium levels, abnormal circulating ca concentration, abnormal circulating ca2+ concentration, abnormal circulating calcium concentration, abnormal concentration of calcium in blood, abnormality of calcium homeostasis, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Any deviation from the normal concentration of calcium in the blood circulation." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=868059
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ConceptID=C4022450
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Abnormal circulating calcium concentration</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>868059</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4022450</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Abnormal concentration of calcium in blood; Abnormality of calcium homeostasis</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0004363">HP:0004363</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Any deviation from the normal concentration of calcium in the blood circulation. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Abnormal circulating calcium concentration</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1701080" ref="tree=MeSH" title="MedGen record for Abnormal circulating metabolite concentration">Abnormal circulating metabolite concentration</a></span><ul><li><span class="TLline"><a href="/medgen/312393" ref="tree=MeSH" title="MedGen record for Abnormal blood ion concentration">Abnormal blood ion concentration</a></span><ul><li><span class="TLline"><a href="/medgen/869223" ref="tree=MeSH" title="MedGen record for Abnormal blood cation concentration">Abnormal blood cation concentration</a></span><ul><li><span class="TLline"><a href="/medgen/869225" ref="tree=MeSH" title="MedGen record for Abnormal blood inorganic cation concentration">Abnormal blood inorganic cation concentration</a></span><ul><li><span class="matched_ds">Abnormal circulating calcium concentration</span><ul><li><span class="TLline"><a href="/medgen/5686" ref="tree=MeSH" title="MedGen record for Hypercalcemia">Hypercalcemia</a></span><ul><li><span class="TLline"><a href="/medgen/56210" ref="tree=MeSH" title="MedGen record for Humoral hypercalcemia of malignancy">Humoral hypercalcemia of malignancy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/5705" ref="tree=MeSH" title="MedGen record for Hypocalcemia">Hypocalcemia</a></span><ul><li><span class="TLline"><a href="/medgen/11748" ref="tree=MeSH" title="MedGen record for Tetany">Tetany</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
</div>
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||
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||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_120640"><div><strong>Primary hypomagnesemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120640</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268448</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial hypomagnesemia with hypercalciuria and nephrocalcinosis is a progressive renal disorder characterized by excessive urinary Ca(2+) and Mg(2+) excretion. There is progressive loss of kidney function, and in about 50% of cases, the need for renal replacement therapy arises as early as the second decade of life (summary by Muller et al., 2006). Amelogenesis imperfecta may also be present in some patients (Bardet et al., 2016). A similar disorder with renal magnesium wasting, renal failure, and nephrocalcinosis (HOMG5; 248190) is caused by mutations in another tight-junction gene, CLDN19 (610036), and is distinguished by the association of severe ocular involvement. For a discussion of phenotypic and genetic heterogeneity of familial hypomagnesemia, see HOMG1 (602014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120640">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_140929"><div><strong>Trichorhinophalangeal dysplasia type I</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>140929</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432233</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Trichorhinophalangeal syndrome (TRPS) comprises TRPS I (caused by a heterozygous pathogenic variant in TRPS1) and TRPS II (caused by a contiguous gene deletion of TRPS1, RAD21, and EXT1). Both TRPS types are characterized by distinctive facial features (large nose with broad nasal ridge and tip and underdeveloped alae; thick and broad medial eyebrows; long philtrum; thin vermilion of the upper lip; and large prominent ears); ectodermal features (fine, sparse, depigmented, and slow-growing hair and dystrophic nails); and skeletal findings (short stature, brachydactyly with ulnar or radial deviation of the fingers, short feet, and early, marked hip dysplasia). TRPS II is additionally characterized by multiple osteochondromas and an increased risk of mild-to-moderate intellectual disability.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/140929">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_196551"><div><strong>Familial X-linked hypophosphatemic vitamin D refractory rickets</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>196551</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0733682</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The phenotypic spectrum of X-linked hypophosphatemia (XLH) ranges from isolated hypophosphatemia to severe lower extremity bowing and/or craniosynostosis, usually involving the sagittal suture with consequent scaphocephaly. XLH typically manifests in the first two years of life with lower extremity bowing due to the onset of weight-bearing; however, it sometimes does not manifest until adulthood, as previously unevaluated short stature. Adults may present with calcification of the tendons, ligaments, and joint capsules, joint pain, fatigue, insufficiency fractures, and impaired mobility. Persons with XLH are prone to spontaneous dental abscesses; sensorineural hearing loss has also been reported. Rarely, individuals with XLH can suffer from spinal stenosis, Chiari I malformation, syringomyelia, and/or raised intracranial pressure.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/196551">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_501133"><div><strong>Autosomal recessive hypophosphatemic bone disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>501133</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1853271</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a rare autosomal recessive disorder characterized by the presence of hypophosphatemia secondary to renal phosphate wasting, radiographic and/or histologic evidence of rickets, limb deformities, muscle weakness, and bone pain. HHRH is distinct from other forms of hypophosphatemic rickets in that affected individuals present with hypercalciuria due to increased serum 1,25-dihydroxyvitamin D levels and increased intestinal calcium absorption (summary by Bergwitz et al., 2006).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/501133">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_355311"><div><strong>Normophosphatemic familial tumoral calcinosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>355311</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1864861</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/355311">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_767342"><div><strong>Osteogenesis imperfecta type 14</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>767342</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3554428</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Osteogenesis imperfecta (OI) is a connective tissue disorder characterized by bone fragility and low bone mass. Due to considerable phenotypic variability, Sillence et al. (1979) developed a classification of OI subtypes based on clinical features and disease severity: OI type I, with blue sclerae (166200); perinatal lethal OI type II, also known as congenital OI (166210); OI type III, a progressively deforming form with normal sclerae (259420); and OI type IV, with normal sclerae (166220). Most cases of OI are autosomal dominant with mutations in 1 of the 2 genes that code for type I collagen alpha chains, COL1A1 (120150) and COL1A2 (120160). Shaheen et al. (2012) described osteogenesis imperfecta type XIV (OI14), an autosomal recessive form of the disorder characterized by variable degrees of severity of multiple fractures and osteopenia, with normal teeth, sclerae, and hearing. Fractures first occur prenatally or by age 6 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/767342">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1637664"><div><strong>Idiopathic basal ganglia calcification 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1637664</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551624</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Primary familial brain calcification (PFBC) is a neurodegenerative disorder with characteristic calcium deposits in the basal ganglia and other brain areas visualized on neuroimaging. Most affected individuals are in good health during childhood and young adulthood and typically present in the fourth to fifth decade with a gradually progressive movement disorder and neuropsychiatric symptoms. The movement disorder first manifests as clumsiness, fatigability, unsteady gait, slow or slurred speech, dysphagia, involuntary movements, or muscle cramping. Neuropsychiatric symptoms, often the first or most prominent manifestations, range from mild difficulty with concentration and memory to changes in personality and/or behavior, to psychosis and dementia. Seizures of various types occur frequently, some individuals experience chronic headache and vertigo; urinary urgency or incontinence may be present.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1637664">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648449"><div><strong>Renal hypomagnesemia 5 with ocular involvement</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648449</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4721891</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">HOMG5 is an autosomal recessive disorder characterized by severe renal magnesium wasting, progressive renal failure, and nephrocalcinosis. Some patients also have severe visual impairment. Amelogenesis imperfecta has been reported in some patients (summary by Konrad et al., 2006 and Yamaguti et al., 2017). For a discussion of genetic heterogeneity of renal hypomagnesemia, see 602014.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648449">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1801631"><div><strong>Osteogenesis imperfecta, IIA 22</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1801631</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5676943</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Osteogenesis imperfecta comprises a group of connective tissue disorders characterized clinically by bone fragility, low bone mass, and increased susceptibility to fractures. Osteogenesis imperfecta type XXII (OI22) is a severe recessive form of the disease (Dubail et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1801631">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_501133" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive hypophosphatemic bone disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_196551" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial X-linked hypophosphatemic vitamin D refractory rickets</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1637664" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Idiopathic basal ganglia calcification 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_355311" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Normophosphatemic familial tumoral calcinosis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_767342" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Osteogenesis imperfecta type 14</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (9)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1801631" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Osteogenesis imperfecta, IIA 22</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120640" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Primary hypomagnesemia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648449" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Renal hypomagnesemia 5 with ocular involvement</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_140929" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Trichorhinophalangeal dysplasia type I</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/19570736">Medical treatment of hypercalcaemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Makras P,
|
||
Papapoulos SE</span><br />
|
||
<span class="medgenPMjournal">Hormones (Athens)</span>
|
||
2009 Apr-Jun;8(2):83-95.
|
||
doi: 10.14310/horm.2002.1225.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19570736" target="_blank">19570736</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19232159">1alpha(OH)D3 One-alpha-hydroxy-cholecalciferol--an active vitamin D analog. Clinical studies on prophylaxis and treatment of secondary hyperparathyroidism in uremic patients on chronic dialysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brandi L</span><br />
|
||
<span class="medgenPMjournal">Dan Med Bull</span>
|
||
2008 Nov;55(4):186-210.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19232159" target="_blank">19232159</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18818881">Intracoronary pharmacotherapy in the management of coronary microvascular dysfunction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kunadian V,
|
||
Zorkun C,
|
||
Williams SP,
|
||
Biller LH,
|
||
Palmer AM,
|
||
Ogando KJ,
|
||
Lew ME,
|
||
Nethala N,
|
||
Gibson WJ,
|
||
Marble SJ,
|
||
Buros JL,
|
||
Gibson CM</span><br />
|
||
<span class="medgenPMjournal">J Thromb Thrombolysis</span>
|
||
2008 Dec;26(3):234-42.
|
||
Epub 2008 Sep 26
|
||
doi: 10.1007/s11239-008-0276-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18818881" target="_blank">18818881</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(abnormal%20circulating%20calcium%20concentration)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (5)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39486479">Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Holick MF</span><br />
|
||
<span class="medgenPMjournal">Endocr Pract</span>
|
||
2024 Dec;30(12):1227-1241.
|
||
Epub 2024 Oct 30
|
||
doi: 10.1016/j.eprac.2024.10.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39486479" target="_blank">39486479</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/39120742">Metabolically healthy obesity in adults with X-linked hypophosphatemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lecoq AL,
|
||
Schilbach K,
|
||
Rocher L,
|
||
Trabado S,
|
||
Briot K,
|
||
Herrou J,
|
||
Forbes A,
|
||
Garnier A,
|
||
Piketty M,
|
||
Bidlingmaier M,
|
||
Rothenbuhler A,
|
||
Linglart A,
|
||
Carette C,
|
||
Chaumet-Riffaud P,
|
||
Kamenický P</span><br />
|
||
<span class="medgenPMjournal">Eur J Endocrinol</span>
|
||
2024 Aug 5;191(2):156-165.
|
||
doi: 10.1093/ejendo/lvae089.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39120742" target="_blank">39120742</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30357886">Genetic approaches to metabolic bone diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hannan FM,
|
||
Newey PJ,
|
||
Whyte MP,
|
||
Thakker RV</span><br />
|
||
<span class="medgenPMjournal">Br J Clin Pharmacol</span>
|
||
2019 Jun;85(6):1147-1160.
|
||
Epub 2018 Nov 28
|
||
doi: 10.1111/bcp.13803.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30357886" target="_blank">30357886</a><a href="/pmc/articles/PMC6533455" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30020507">Adiposity, vitamin D requirements, and clinical implications for obesity-related metabolic abnormalities.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hyppönen E,
|
||
Boucher BJ</span><br />
|
||
<span class="medgenPMjournal">Nutr Rev</span>
|
||
2018 Sep 1;76(9):678-692.
|
||
doi: 10.1093/nutrit/nuy034.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30020507" target="_blank">30020507</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26749423">Circulating calcium concentrations, vascular disease and mortality: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reid IR,
|
||
Gamble GD,
|
||
Bolland MJ</span><br />
|
||
<span class="medgenPMjournal">J Intern Med</span>
|
||
2016 Jun;279(6):524-40.
|
||
Epub 2016 Jan 8
|
||
doi: 10.1111/joim.12464.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26749423" target="_blank">26749423</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20calcium%20concentration%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (55)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32101626">Hyperparathyroidism in Patients With X-Linked Hypophosphatemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lecoq AL,
|
||
Chaumet-Riffaud P,
|
||
Blanchard A,
|
||
Dupeux M,
|
||
Rothenbuhler A,
|
||
Lambert B,
|
||
Durand E,
|
||
Boros E,
|
||
Briot K,
|
||
Silve C,
|
||
Francou B,
|
||
Piketty M,
|
||
Chanson P,
|
||
Brailly-Tabard S,
|
||
Linglart A,
|
||
Kamenický P</span><br />
|
||
<span class="medgenPMjournal">J Bone Miner Res</span>
|
||
2020 Jul;35(7):1263-1273.
|
||
Epub 2020 Mar 27
|
||
doi: 10.1002/jbmr.3992.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32101626" target="_blank">32101626</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30357886">Genetic approaches to metabolic bone diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hannan FM,
|
||
Newey PJ,
|
||
Whyte MP,
|
||
Thakker RV</span><br />
|
||
<span class="medgenPMjournal">Br J Clin Pharmacol</span>
|
||
2019 Jun;85(6):1147-1160.
|
||
Epub 2018 Nov 28
|
||
doi: 10.1111/bcp.13803.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30357886" target="_blank">30357886</a><a href="/pmc/articles/PMC6533455" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25448684">Eryptosis in lead-exposed workers.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aguilar-Dorado IC,
|
||
Hernández G,
|
||
Quintanar-Escorza MA,
|
||
Maldonado-Vega M,
|
||
Rosas-Flores M,
|
||
Calderón-Salinas JV</span><br />
|
||
<span class="medgenPMjournal">Toxicol Appl Pharmacol</span>
|
||
2014 Dec 1;281(2):195-202.
|
||
Epub 2014 Oct 27
|
||
doi: 10.1016/j.taap.2014.10.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25448684" target="_blank">25448684</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19570736">Medical treatment of hypercalcaemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Makras P,
|
||
Papapoulos SE</span><br />
|
||
<span class="medgenPMjournal">Hormones (Athens)</span>
|
||
2009 Apr-Jun;8(2):83-95.
|
||
doi: 10.14310/horm.2002.1225.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19570736" target="_blank">19570736</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2435657">Exaggerated renal vasodilator response to calcium entry blockade in first-degree relatives of essential hypertensive subjects.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Blackshear JL,
|
||
Garnic D,
|
||
Williams GH,
|
||
Harrington DP,
|
||
Hollenberg NK</span><br />
|
||
<span class="medgenPMjournal">Hypertension</span>
|
||
1987 Apr;9(4):384-9.
|
||
doi: 10.1161/01.hyp.9.4.384.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2435657" target="_blank">2435657</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20calcium%20concentration%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (40)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39486479">Revisiting Vitamin D Guidelines: A Critical Appraisal of the Literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Holick MF</span><br />
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2024 Dec;30(12):1227-1241.
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Epub 2024 Oct 30
|
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|
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<span class="bold">PMID: </span><a href="/pubmed/39486479" target="_blank">39486479</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30020507">Adiposity, vitamin D requirements, and clinical implications for obesity-related metabolic abnormalities.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hyppönen E,
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<span class="medgenPMjournal">Nutr Rev</span>
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2018 Sep 1;76(9):678-692.
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<div class="nl"><a target="_blank" href="/pubmed/25828570">Dialysate and serum potassium in hemodialysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hung AM,
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Hakim RM</span><br />
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<span class="medgenPMjournal">Am J Kidney Dis</span>
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2015 Jul;66(1):125-32.
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Epub 2015 Mar 28
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|
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<span class="bold">PMID: </span><a href="/pubmed/25828570" target="_blank">25828570</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11474477">Pycnodysostosis: clinical, radiologic, and endocrine evaluation and linear growth after growth hormone therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Soliman AT,
|
||
Ramadan MA,
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Sherif A,
|
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Aziz Bedair ES,
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Rizk MM</span><br />
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<span class="medgenPMjournal">Metabolism</span>
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2001 Aug;50(8):905-11.
|
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doi: 10.1053/meta.2001.24924.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11474477" target="_blank">11474477</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11540313">Anabolic effects of fluoride on bone.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pak CY,
|
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Zerwekh JE,
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Antich P</span><br />
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<span class="medgenPMjournal">Trends Endocrinol Metab</span>
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1995 Sep;6(7):229-34.
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<span class="bold">PMID: </span><a href="/pubmed/11540313" target="_blank">11540313</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20calcium%20concentration%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (50)</a></div><h3 class="subhead">Prognosis</h3>
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||
<div class="nl"><a target="_blank" href="/pubmed/33669042">Cardiac T-Tubule cBIN1-Microdomain, a Diagnostic Marker and Therapeutic Target of Heart Failure.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Li J,
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Richmond B,
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Hong T</span><br />
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2021 Feb 25;22(5)
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doi: 10.3390/ijms22052299.
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<span class="bold">PMID: </span><a href="/pubmed/33669042" target="_blank">33669042</a><a href="/pmc/articles/PMC7956774" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/30357886">Genetic approaches to metabolic bone diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hannan FM,
|
||
Newey PJ,
|
||
Whyte MP,
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Thakker RV</span><br />
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<span class="medgenPMjournal">Br J Clin Pharmacol</span>
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2019 Jun;85(6):1147-1160.
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Epub 2018 Nov 28
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doi: 10.1111/bcp.13803.
|
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<span class="bold">PMID: </span><a href="/pubmed/30357886" target="_blank">30357886</a><a href="/pmc/articles/PMC6533455" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25828570">Dialysate and serum potassium in hemodialysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hung AM,
|
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Hakim RM</span><br />
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<span class="medgenPMjournal">Am J Kidney Dis</span>
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2015 Jul;66(1):125-32.
|
||
Epub 2015 Mar 28
|
||
doi: 10.1053/j.ajkd.2015.02.322.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25828570" target="_blank">25828570</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24311704">Disordered FGF23 and mineral metabolism in children with CKD.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Portale AA,
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Wolf M,
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Jüppner H,
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Messinger S,
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Kumar J,
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Wesseling-Perry K,
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Schwartz GJ,
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Furth SL,
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2014 Feb;9(2):344-53.
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<span class="bold">PMID: </span><a href="/pubmed/24311704" target="_blank">24311704</a><a href="/pmc/articles/PMC3913243" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21803465">Association of kidney function, vitamin D deficiency, and circulating markers of mineral and bone disorders in CKD.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ureña-Torres P,
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Metzger M,
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Haymann JP,
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Karras A,
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Boffa JJ,
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Flamant M,
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Vrtovsnik F,
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Gauci C,
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Froissart M,
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Houillier P,
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Stengel B;
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<span class="medgenPMjournal">Am J Kidney Dis</span>
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2011 Oct;58(4):544-53.
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Epub 2011 Jul 31
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|
||
<span class="bold">PMID: </span><a href="/pubmed/21803465" target="_blank">21803465</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20calcium%20concentration%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (21)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37537395">SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Iida H,
|
||
Kono T,
|
||
Lee CC,
|
||
Krishnan P,
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||
Arvin MC,
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||
Weaver SA,
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||
Jarvela TS,
|
||
Branco RCS,
|
||
McLaughlin MR,
|
||
Bone RN,
|
||
Tong X,
|
||
Arvan P,
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||
Lindberg I,
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||
Evans-Molina C</span><br />
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||
<span class="medgenPMjournal">Diabetologia</span>
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||
2023 Nov;66(11):2042-2061.
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||
Epub 2023 Aug 4
|
||
doi: 10.1007/s00125-023-05979-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37537395" target="_blank">37537395</a><a href="/pmc/articles/PMC10542743" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30357886">Genetic approaches to metabolic bone diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hannan FM,
|
||
Newey PJ,
|
||
Whyte MP,
|
||
Thakker RV</span><br />
|
||
<span class="medgenPMjournal">Br J Clin Pharmacol</span>
|
||
2019 Jun;85(6):1147-1160.
|
||
Epub 2018 Nov 28
|
||
doi: 10.1111/bcp.13803.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30357886" target="_blank">30357886</a><a href="/pmc/articles/PMC6533455" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26749423">Circulating calcium concentrations, vascular disease and mortality: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reid IR,
|
||
Gamble GD,
|
||
Bolland MJ</span><br />
|
||
<span class="medgenPMjournal">J Intern Med</span>
|
||
2016 Jun;279(6):524-40.
|
||
Epub 2016 Jan 8
|
||
doi: 10.1111/joim.12464.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26749423" target="_blank">26749423</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11474477">Pycnodysostosis: clinical, radiologic, and endocrine evaluation and linear growth after growth hormone therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Soliman AT,
|
||
Ramadan MA,
|
||
Sherif A,
|
||
Aziz Bedair ES,
|
||
Rizk MM</span><br />
|
||
<span class="medgenPMjournal">Metabolism</span>
|
||
2001 Aug;50(8):905-11.
|
||
doi: 10.1053/meta.2001.24924.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11474477" target="_blank">11474477</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6324253">Metabolism of 1,25-dihydroxyvitamin D3.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kumar R</span><br />
|
||
<span class="medgenPMjournal">Physiol Rev</span>
|
||
1984 Apr;64(2):478-504.
|
||
doi: 10.1152/physrev.1984.64.2.478.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6324253" target="_blank">6324253</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20calcium%20concentration%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (55)</a></div></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/26749423">Circulating calcium concentrations, vascular disease and mortality: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reid IR,
|
||
Gamble GD,
|
||
Bolland MJ</span><br />
|
||
<span class="medgenPMjournal">J Intern Med</span>
|
||
2016 Jun;279(6):524-40.
|
||
Epub 2016 Jan 8
|
||
doi: 10.1111/joim.12464.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26749423" target="_blank">26749423</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20calcium%20concentration%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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