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<meta name="keywords" content="C4016398, costello syndrome, severe, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="" /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=864835
|
||
ConceptID=C4016398
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Costello syndrome, severe</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>864835</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4016398</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>COSTELLO SYNDROME, SEVERE</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/190020" target="_blank">190020</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36533679">New prospectives on treatment opportunities in RASopathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gelb BD,
|
||
Yohe ME,
|
||
Wolf C,
|
||
Andelfinger G</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet C Semin Med Genet</span>
|
||
2022 Dec;190(4):541-560.
|
||
Epub 2022 Dec 19
|
||
doi: 10.1002/ajmg.c.32024.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36533679" target="_blank">36533679</a><a href="/pmc/articles/PMC10150944" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36515923">Management of nutritional and gastrointestinal issues in RASopathies: A narrative review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Onesimo R,
|
||
Giorgio V,
|
||
Viscogliosi G,
|
||
Sforza E,
|
||
Kuczynska E,
|
||
Margiotta G,
|
||
Iademarco M,
|
||
Proli F,
|
||
Rigante D,
|
||
Zampino G,
|
||
Leoni C</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet C Semin Med Genet</span>
|
||
2022 Dec;190(4):478-493.
|
||
Epub 2022 Dec 14
|
||
doi: 10.1002/ajmg.c.32019.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36515923" target="_blank">36515923</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34776080">Hypertrophic Cardiomyopathy in RASopathies: Diagnosis, Clinical Characteristics, Prognostic Implications, and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lioncino M,
|
||
Monda E,
|
||
Verrillo F,
|
||
Moscarella E,
|
||
Calcagni G,
|
||
Drago F,
|
||
Marino B,
|
||
Digilio MC,
|
||
Putotto C,
|
||
Calabrò P,
|
||
Russo MG,
|
||
Roberts AE,
|
||
Gelb BD,
|
||
Tartaglia M,
|
||
Limongelli G</span><br />
|
||
<span class="medgenPMjournal">Heart Fail Clin</span>
|
||
2022 Jan;18(1):19-29.
|
||
Epub 2021 Oct 25
|
||
doi: 10.1016/j.hfc.2021.07.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34776080" target="_blank">34776080</a><a href="/pmc/articles/PMC9674037" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(costello%20syndrome%2C%20severe)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (6)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38847227">RASopathies - what they reveal about RAS/MAPK signaling in skeletal muscle development.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rauen KA,
|
||
Tidyman WE</span><br />
|
||
<span class="medgenPMjournal">Dis Model Mech</span>
|
||
2024 Jun 1;17(6)
|
||
Epub 2024 Jun 7
|
||
doi: 10.1242/dmm.050609.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38847227" target="_blank">38847227</a><a href="/pmc/articles/PMC11179721" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37278994">Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thaweethai T,
|
||
Jolley SE,
|
||
Karlson EW,
|
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Adorisio R,
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|
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2020 Aug 13;8(8):CD005552.
|
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doi: 10.1002/14651858.CD005552.pub3.
|
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<span class="bold">PMID: </span><a href="/pubmed/32794179" target="_blank">32794179</a><a href="/pmc/articles/PMC7437400" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Costello%20syndrome%2C%20severe%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (30)</a></div><h3 class="subhead">Prognosis</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/38136934">The Cardiofaciocutaneous Syndrome: From Genetics to Prognostic-Therapeutic Implications.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Scorrano G,
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David E,
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Calì E,
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Chimenz R,
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La Bella S,
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Di Ludovico A,
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Di Rosa G,
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Gitto E,
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Mankad K,
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Nardello R,
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Mangano GD,
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Leoni C,
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Ceravolo G</span><br />
|
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<span class="medgenPMjournal">Genes (Basel)</span>
|
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2023 Nov 22;14(12)
|
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doi: 10.3390/genes14122111.
|
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<span class="bold">PMID: </span><a href="/pubmed/38136934" target="_blank">38136934</a><a href="/pmc/articles/PMC10742720" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/37065762">Syndromic forms of congenital hyperinsulinism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zenker M,
|
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Mohnike K,
|
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Palm K</span><br />
|
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<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
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2023;14:1013874.
|
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Epub 2023 Mar 30
|
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doi: 10.3389/fendo.2023.1013874.
|
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<span class="bold">PMID: </span><a href="/pubmed/37065762" target="_blank">37065762</a><a href="/pmc/articles/PMC10098214" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/34776080">Hypertrophic Cardiomyopathy in RASopathies: Diagnosis, Clinical Characteristics, Prognostic Implications, and Management.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lioncino M,
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Monda E,
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Verrillo F,
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Moscarella E,
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Calcagni G,
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Drago F,
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Marino B,
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Digilio MC,
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Putotto C,
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Calabrò P,
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Russo MG,
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Roberts AE,
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Gelb BD,
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Tartaglia M,
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Limongelli G</span><br />
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<span class="medgenPMjournal">Heart Fail Clin</span>
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2022 Jan;18(1):19-29.
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Epub 2021 Oct 25
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doi: 10.1016/j.hfc.2021.07.004.
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<span class="bold">PMID: </span><a href="/pubmed/34776080" target="_blank">34776080</a><a href="/pmc/articles/PMC9674037" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/34551225">Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">El Sahly HM,
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Baden LR,
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Essink B,
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Doblecki-Lewis S,
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Martin JM,
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Anderson EJ,
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Campbell TB,
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Clark J,
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Jackson LA,
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Fichtenbaum CJ,
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Zervos M,
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Rankin B,
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Eder F,
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Feldman G,
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Kennelly C,
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Han-Conrad L,
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Levin M,
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Neuzil KM,
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Corey L,
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Gilbert P,
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Janes H,
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Follmann D,
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Marovich M,
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Polakowski L,
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Mascola JR,
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Ledgerwood JE,
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Graham BS,
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August A,
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Clouting H,
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Deng W,
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Han S,
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Leav B,
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Manzo D,
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Pajon R,
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Schödel F,
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Tomassini JE,
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Zhou H,
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Miller J;
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COVE Study Group</span><br />
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<span class="medgenPMjournal">N Engl J Med</span>
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2021 Nov 4;385(19):1774-1785.
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Epub 2021 Sep 22
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doi: 10.1056/NEJMoa2113017.
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<span class="bold">PMID: </span><a href="/pubmed/34551225" target="_blank">34551225</a><a href="/pmc/articles/PMC8482810" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/33378609">Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Baden LR,
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El Sahly HM,
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Essink B,
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Kotloff K,
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Frey S,
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Novak R,
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Diemert D,
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Spector SA,
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Rouphael N,
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Creech CB,
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McGettigan J,
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Khetan S,
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Segall N,
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Solis J,
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Brosz A,
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Fierro C,
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Schwartz H,
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Neuzil K,
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Corey L,
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Gilbert P,
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Janes H,
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Follmann D,
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Marovich M,
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Mascola J,
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Polakowski L,
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Ledgerwood J,
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Graham BS,
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Bennett H,
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Pajon R,
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Knightly C,
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Leav B,
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Deng W,
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Zhou H,
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Han S,
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Ivarsson M,
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Miller J,
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Zaks T;
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2021 Feb 4;384(5):403-416.
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Epub 2020 Dec 30
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<span class="bold">PMID: </span><a href="/pubmed/33378609" target="_blank">33378609</a><a href="/pmc/articles/PMC7787219" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Costello%20syndrome%2C%20severe%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (39)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37278994">Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Thaweethai T,
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Deeks SG,
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Sciurba FC,
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Whiteheart SW,
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Wisnivesky JP,
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<span class="bold">PMID: </span><a href="/pubmed/37278994" target="_blank">37278994</a><a href="/pmc/articles/PMC10214179" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/37065762">Syndromic forms of congenital hyperinsulinism.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Zenker M,
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Mohnike K,
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Palm K</span><br />
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<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
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2023;14:1013874.
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Epub 2023 Mar 30
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doi: 10.3389/fendo.2023.1013874.
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<span class="bold">PMID: </span><a href="/pubmed/37065762" target="_blank">37065762</a><a href="/pmc/articles/PMC10098214" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/36515923">Management of nutritional and gastrointestinal issues in RASopathies: A narrative review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Onesimo R,
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Giorgio V,
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Viscogliosi G,
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Sforza E,
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Proli F,
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2022 Dec;190(4):478-493.
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<span class="bold">PMID: </span><a href="/pubmed/36515923" target="_blank">36515923</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34551225">Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">El Sahly HM,
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Baden LR,
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Essink B,
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Doblecki-Lewis S,
|
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Martin JM,
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Anderson EJ,
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Campbell TB,
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Clark J,
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Jackson LA,
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Fichtenbaum CJ,
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Zervos M,
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Rankin B,
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Eder F,
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Feldman G,
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Kennelly C,
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Han-Conrad L,
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Levin M,
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Neuzil KM,
|
||
Corey L,
|
||
Gilbert P,
|
||
Janes H,
|
||
Follmann D,
|
||
Marovich M,
|
||
Polakowski L,
|
||
Mascola JR,
|
||
Ledgerwood JE,
|
||
Graham BS,
|
||
August A,
|
||
Clouting H,
|
||
Deng W,
|
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Han S,
|
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Leav B,
|
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Manzo D,
|
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Pajon R,
|
||
Schödel F,
|
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Tomassini JE,
|
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Zhou H,
|
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Miller J;
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COVE Study Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
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2021 Nov 4;385(19):1774-1785.
|
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Epub 2021 Sep 22
|
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doi: 10.1056/NEJMoa2113017.
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||
<span class="bold">PMID: </span><a href="/pubmed/34551225" target="_blank">34551225</a><a href="/pmc/articles/PMC8482810" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33378609">Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baden LR,
|
||
El Sahly HM,
|
||
Essink B,
|
||
Kotloff K,
|
||
Frey S,
|
||
Novak R,
|
||
Diemert D,
|
||
Spector SA,
|
||
Rouphael N,
|
||
Creech CB,
|
||
McGettigan J,
|
||
Khetan S,
|
||
Segall N,
|
||
Solis J,
|
||
Brosz A,
|
||
Fierro C,
|
||
Schwartz H,
|
||
Neuzil K,
|
||
Corey L,
|
||
Gilbert P,
|
||
Janes H,
|
||
Follmann D,
|
||
Marovich M,
|
||
Mascola J,
|
||
Polakowski L,
|
||
Ledgerwood J,
|
||
Graham BS,
|
||
Bennett H,
|
||
Pajon R,
|
||
Knightly C,
|
||
Leav B,
|
||
Deng W,
|
||
Zhou H,
|
||
Han S,
|
||
Ivarsson M,
|
||
Miller J,
|
||
Zaks T;
|
||
COVE Study Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2021 Feb 4;384(5):403-416.
|
||
Epub 2020 Dec 30
|
||
doi: 10.1056/NEJMoa2035389.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33378609" target="_blank">33378609</a><a href="/pmc/articles/PMC7787219" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Costello%20syndrome%2C%20severe%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (40)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37462232">Statins for women with polycystic ovary syndrome not actively trying to conceive.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Xiong T,
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Fraison E,
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Kolibianaki E,
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Costello MF,
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Venetis C,
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Kostova EB</span><br />
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<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
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2023 Jul 18;7(7):CD008565.
|
||
doi: 10.1002/14651858.CD008565.pub3.
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||
<span class="bold">PMID: </span><a href="/pubmed/37462232" target="_blank">37462232</a><a href="/pmc/articles/PMC10353291" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37437914">SARS-CoV-2 post-acute sequelae in previously hospitalised patients: systematic literature review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kelly JD,
|
||
Curteis T,
|
||
Rawal A,
|
||
Murton M,
|
||
Clark LJ,
|
||
Jafry Z,
|
||
Shah-Gupta R,
|
||
Berry M,
|
||
Espinueva A,
|
||
Chen L,
|
||
Abdelghany M,
|
||
Sweeney DA,
|
||
Quint JK</span><br />
|
||
<span class="medgenPMjournal">Eur Respir Rev</span>
|
||
2023 Sep 30;32(169)
|
||
Epub 2023 Jul 12
|
||
doi: 10.1183/16000617.0254-2022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37437914" target="_blank">37437914</a><a href="/pmc/articles/PMC10336551" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32794179">Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fraison E,
|
||
Kostova E,
|
||
Moran LJ,
|
||
Bilal S,
|
||
Ee CC,
|
||
Venetis C,
|
||
Costello MF</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2020 Aug 13;8(8):CD005552.
|
||
doi: 10.1002/14651858.CD005552.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32794179" target="_blank">32794179</a><a href="/pmc/articles/PMC7437400" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17261574">Metformin versus oral contraceptive pill in polycystic ovary syndrome: a Cochrane review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Costello MF,
|
||
Shrestha B,
|
||
Eden J,
|
||
Johnson NP,
|
||
Sjoblom P</span><br />
|
||
<span class="medgenPMjournal">Hum Reprod</span>
|
||
2007 May;22(5):1200-9.
|
||
Epub 2007 Jan 29
|
||
doi: 10.1093/humrep/dem005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17261574" target="_blank">17261574</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17253562">Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Costello M,
|
||
Shrestha B,
|
||
Eden J,
|
||
Sjoblom P,
|
||
Johnson N</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2007 Jan 24;(1):CD005552.
|
||
doi: 10.1002/14651858.CD005552.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17253562" target="_blank">17253562</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Costello%20syndrome%2C%20severe%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(costello%20syndrome%2C%20severe)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Costello%20syndrome%2C%20severe%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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