publicdata/nih-gov
1
0
Fork 0
Code Issues Pull requests Projects Releases Packages Wiki Activity Actions
nih-gov/www.ncbi.nlm.nih.gov/medgen/C3469524/index.html

2352 lines
No EOL
102 KiB
HTML
Raw Blame History

This file contains invisible Unicode characters

This file contains invisible Unicode characters that are indistinguishable to humans but may be processed differently by a computer. If you think that this is intentional, you can safely ignore this warning. Use the Escape button to reveal them.

<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml" lang="en" xml:lang="en">
<head xmlns:xi="http://www.w3.org/2001/XInclude"><meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
<!-- meta -->
<meta name="keywords" content="C3469524, finding, prostate cancer susceptibility, prostate cancer, susceptibility to, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="" /><meta name="robots" content="index,nofollow,noarchive" />
<meta name="ncbi_app" content="entrez" /><meta name="ncbi_db" content="medgen" /><meta name="ncbi_term" content="c3469524[conceptid]" /><meta name="ncbi_report" content="fullreport" /><meta name="ncbi_format" content="html" /><meta name="ncbi_pagesize" content="20" /><meta name="ncbi_sortorder" content="default" /><meta name="ncbi_pageno" content="1" /><meta name="ncbi_resultcount" content="1" /><meta name="ncbi_op" content="search" /><meta name="ncbi_pdid" content="fullreport" /><meta name="ncbi_sessionid" content="CE8B5AF87C7FFCB1_0191SID" /><meta name="ncbi_filter" content="clinical" /><meta name="ncbi_stat" content="false" /><meta name="ncbi_hitstat" content="false" />
<!-- title -->
<title>Prostate cancer susceptibility (Concept Id: C3469524)
- MedGen - NCBI</title>
<!-- Common JS and CSS -->
<script type="text/javascript">
var ncbi_startTime = new Date();
</script>
<script type="text/javascript" src="https://static.pubmed.gov/core/jig/1.15.10/js/jig.min.js"></script>
<link xmlns="http://www.w3.org/1999/xhtml" type="text/css" rel="stylesheet" href="//static.pubmed.gov/portal/portal3rc.fcgi/4218191/css/4207974/4206132.css" xml:base="http://127.0.0.1/sites/static/header_footer/" />
<link rel="shortcut icon" href="//www.ncbi.nlm.nih.gov/favicon.ico" /><meta name="ncbi_phid" content="CE8D62247CD38DE10000000000520045.m_29" /><script type="text/javascript"><!--
var ScriptPath = '/portal/';
var objHierarchy = {"name":"EntrezSystem2","type":"Layout","realname":"EntrezSystem2",
"children":[{"name":"EntrezSystem2.PEntrez","type":"Cluster","realname":"EntrezSystem2.PEntrez",
"children":[{"name":"EntrezSystem2.PEntrez.DbConnector","type":"Portlet","realname":"EntrezSystem2.PEntrez.PEntrez.DbConnector","shortname":"DbConnector"},
{"name":"EntrezSystem2.PEntrez.ParamContainer","type":"Portlet","realname":"EntrezSystem2.PEntrez.PEntrez.ParamContainer","shortname":"ParamContainer"},
{"name":"EntrezSystem2.PEntrez.MyNcbi","type":"Portlet","realname":"EntrezSystem2.PEntrez.PEntrez.MyNcbi","shortname":"MyNcbi"},
{"name":"EntrezSystem2.PEntrez.UserPreferenceUrlParamContainer","type":"Portlet","realname":"EntrezSystem2.PEntrez.PEntrez.UserPreferenceUrlParamContainer","shortname":"UserPreferenceUrlParamContainer"},
{"name":"EntrezSystem2.PEntrez.GridProperty","type":"Portlet","realname":"EntrezSystem2.PEntrez.PEntrez.GridProperty","shortname":"GridProperty"},
{"name":"EntrezSystem2.PEntrez.MedGen","type":"Cluster","realname":"EntrezSystem2.PEntrez.MedGen",
"children":[{"name":"EntrezSystem2.PEntrez.MedGen.NoPortlet","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NoPortlet","shortname":"NoPortlet"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_PageController","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_PageController","shortname":"MedGen_PageController"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_SearchBar","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_SearchBar","shortname":"MedGen_SearchBar"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_BotRequest","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_BotRequest","shortname":"MedGen_BotRequest"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_LimitsTab","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_LimitsTab","shortname":"MedGen_LimitsTab"},
{"name":"EntrezSystem2.PEntrez.MedGen.Entrez_Facets","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.Entrez_Facets","shortname":"Entrez_Facets"},
{"name":"EntrezSystem2.PEntrez.MedGen.Entrez_Clipboard","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.Entrez_Clipboard","shortname":"Entrez_Clipboard"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_StaticParts","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_StaticParts","shortname":"MedGen_StaticParts"},
{"name":"EntrezSystem2.PEntrez.MedGen.Entrez_Messages","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.Entrez_Messages","shortname":"Entrez_Messages"},
{"name":"EntrezSystem2.PEntrez.MedGen.NcbiJSCheck","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NcbiJSCheck","shortname":"NcbiJSCheck"},
{"name":"EntrezSystem2.PEntrez.MedGen.NCBIFooter_dynamic","type":"Cluster","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NCBIFooter_dynamic",
"children":[{"name":"EntrezSystem2.PEntrez.MedGen.NCBIFooter_dynamic.Footer_ExtraData","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NCBIFooter_dynamic.Footer_ExtraData","shortname":"Footer_ExtraData"},
{"name":"EntrezSystem2.PEntrez.MedGen.NCBIFooter_dynamic.NCBIFooter_dynamic","type":"Cluster","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NCBIFooter_dynamic.NCBIFooter_dynamic",
"children":[{"name":"EntrezSystem2.PEntrez.MedGen.NCBIFooter_dynamic.NCBIFooter_dynamic.NCBIBreadcrumbs","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NCBIFooter_dynamic.NCBIFooter_dynamic.NCBIBreadcrumbs","shortname":"NCBIBreadcrumbs"},
{"name":"EntrezSystem2.PEntrez.MedGen.NCBIFooter_dynamic.NCBIFooter_dynamic.NCBIHelpDesk","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NCBIFooter_dynamic.NCBIFooter_dynamic.NCBIHelpDesk","shortname":"NCBIHelpDesk"},
{"name":"EntrezSystem2.PEntrez.MedGen.NCBIFooter_dynamic.NCBIFooter_dynamic.NCBIApplog_NoScript_Ping","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.Entrez_Database.NCBIFooter_dynamic.NCBIFooter_dynamic.NCBIApplog_NoScript_Ping","shortname":"NCBIApplog_NoScript_Ping"}]}]},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel","type":"Cluster","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel",
"children":[{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.blankToolPanel","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.blankToolPanel","shortname":"blankToolPanel"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ResultsController","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ResultsController","shortname":"MedGen_ResultsController"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_FiltersPortlet","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_FiltersPortlet","shortname":"MedGen_FiltersPortlet"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_Pager","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.Entrez_Pager","shortname":"Entrez_Pager"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar","shortname":"MedGen_DisplayBar"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HelpFormAttributes","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.HelpFormAttributes","shortname":"HelpFormAttributes"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_Collections","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.Entrez_Collections","shortname":"Entrez_Collections"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.SpellCheck","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.SpellCheck","shortname":"SpellCheck"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.SearchEngineReferralCheck","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.SearchEngineReferralCheck","shortname":"SearchEngineReferralCheck"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.WrongDbSensor","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.WrongDbSensor","shortname":"WrongDbSensor"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.KnowledgePanel","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.KnowledgePanel","shortname":"KnowledgePanel"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.HistoryDisplay","shortname":"HistoryDisplay"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Discovery_SearchDetails","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.Entrez_ResultsPanel.Discovery_SearchDetails","shortname":"Discovery_SearchDetails"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.mg_GeneSensor","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.mg_GeneSensor","shortname":"mg_GeneSensor"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ClinFeatureSearch","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ClinFeatureSearch","shortname":"MedGen_ClinFeatureSearch"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_RVFull","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_RVFull","shortname":"MedGen_RVFull"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster","type":"Cluster","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster",
"children":[{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks","shortname":"MedGenDiscoveryDbLinks"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGen_SingleItemSupl","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGen_SingleItemSupl","shortname":"MedGen_SingleItemSupl"},
{"name":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews","type":"Portlet","realname":"EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews","shortname":"MedGenReviews"}]}]}]}]}]};
--></script>
<meta name='referrer' content='origin-when-cross-origin'/><link type="text/css" rel="stylesheet" href="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/css/3808861/3917732/3974050/3751656/3395415/4221762/14534/4062871/4186458/4075711/12930/4033350/4128070/3861632/4013176/4212357/4064428/4186491/9685/2279/3395586.css" /><link type="text/css" rel="stylesheet" href="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/css/3501913/1303451.css" media="print" /><script type="text/javascript">
var ObjectLinks=[{i:0, ename: "p$ExL", esid:"*", sname: "p$ExL", ssid:"*", dname:"p$el", dsid:"0",m:"CopyValue",p:[],f: function(src, dst) {fn_CopyValue(src, dst);}}]
var ActiveNames = {"p$ExL":1, "EntrezSystem2.PEntrez.DbConnector.Cmd":0, "EntrezSystem2.PEntrez.DbConnector.Db":0, "EntrezSystem2.PEntrez.DbConnector.IdsFromResult":0, "EntrezSystem2.PEntrez.DbConnector.LastDb":0, "EntrezSystem2.PEntrez.DbConnector.LastIdsFromResult":0, "EntrezSystem2.PEntrez.DbConnector.LastQueryKey":0, "EntrezSystem2.PEntrez.DbConnector.LastTabCmd":0, "EntrezSystem2.PEntrez.DbConnector.LinkName":0, "EntrezSystem2.PEntrez.DbConnector.LinkReadableName":0, "EntrezSystem2.PEntrez.DbConnector.LinkSrcDb":0, "EntrezSystem2.PEntrez.DbConnector.QueryKey":0, "EntrezSystem2.PEntrez.DbConnector.TabCmd":0, "EntrezSystem2.PEntrez.DbConnector.Term":0, "EntrezSystem2.PEntrez.MedGen.MedGen_PageController.PreviousPageName":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Cmd":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryOn":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.Display":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.FFormat":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.FileFormat":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.Format":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.LastFormat":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.LastPageSize":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.LastPresentation":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PageSize":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.Presentation":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PrevPageSize":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PrevPresentation":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PrevSort":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendTo":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendToSubmit":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SetDisplay":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.sPresentation":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ResultsController.ResultCount":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ResultsController.RunLastQuery":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter":0, "EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter":0};
</script></head>
<body>
<div class="grid">
<div class="col twelve_col nomargin shadow">
<form enctype="application/x-www-form-urlencoded" name="EntrezForm" method="post" onsubmit="return false;" action="/medgen" id="EntrezForm">
<div xmlns:xi="http://www.w3.org/2001/XInclude">
<!-- no javascript message -->
<noscript>
<p class="nojs">
<strong>Warning:</strong>
The NCBI web site requires JavaScript to function.
<a href="/guide/browsers/#enablejs" title="Learn how to enable JavaScript" target="_blank">more...</a>
</p>
</noscript>
<div xmlns="http://www.w3.org/1999/xhtml" id="universal_header" xml:base="http://127.0.0.1/sites/static/header_footer/">
<section class="usa-banner">
<div class="usa-accordion">
<header class="usa-banner-header">
<div class="usa-grid usa-banner-inner">
<img src="https://www.ncbi.nlm.nih.gov/coreutils/uswds/img/favicons/favicon-57.png" alt="U.S. flag" />
<p>An official website of the United States government</p>
<button class="non-usa-accordion-button usa-banner-button" aria-expanded="false" aria-controls="gov-banner-top" type="button">
<span class="usa-banner-button-text">Here's how you know</span>
</button>
</div>
</header>
<div class="usa-banner-content usa-grid usa-accordion-content" id="gov-banner-top" aria-hidden="true">
<div class="usa-banner-guidance-gov usa-width-one-half">
<img class="usa-banner-icon usa-media_block-img" src="https://www.ncbi.nlm.nih.gov/coreutils/uswds/img/icon-dot-gov.svg" alt="Dot gov" />
<div class="usa-media_block-body">
<p>
<strong>The .gov means it's official.</strong>
<br />
Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you're on a federal
government site.
</p>
</div>
</div>
<div class="usa-banner-guidance-ssl usa-width-one-half">
<img class="usa-banner-icon usa-media_block-img" src="https://www.ncbi.nlm.nih.gov/coreutils/uswds/img/icon-https.svg" alt="Https" />
<div class="usa-media_block-body">
<p>
<strong>The site is secure.</strong>
<br />
The <strong>https://</strong> ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.
</p>
</div>
</div>
</div>
</div>
</section>
<div class="usa-overlay"></div>
<header class="ncbi-header" role="banner" data-section="Header">
<div class="usa-grid">
<div class="usa-width-one-whole">
<div class="ncbi-header__logo">
<a href="/" class="logo" aria-label="NCBI Logo" data-ga-action="click_image" data-ga-label="NIH NLM Logo">
<img src="https://www.ncbi.nlm.nih.gov/coreutils/nwds/img/logos/AgencyLogo.svg" alt="NIH NLM Logo" />
</a>
</div>
<div class="ncbi-header__account">
<a id="account_login" href="https://account.ncbi.nlm.nih.gov" class="usa-button header-button" style="display:none" data-ga-action="open_menu" data-ga-label="account_menu">Log in</a>
<button id="account_info" class="header-button" style="display:none" aria-controls="account_popup" type="button">
<span class="fa fa-user" aria-hidden="true">
<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" width="20px" height="20px">
<g style="fill: #fff">
<ellipse cx="12" cy="8" rx="5" ry="6"></ellipse>
<path d="M21.8,19.1c-0.9-1.8-2.6-3.3-4.8-4.2c-0.6-0.2-1.3-0.2-1.8,0.1c-1,0.6-2,0.9-3.2,0.9s-2.2-0.3-3.2-0.9 C8.3,14.8,7.6,14.7,7,15c-2.2,0.9-3.9,2.4-4.8,4.2C1.5,20.5,2.6,22,4.1,22h15.8C21.4,22,22.5,20.5,21.8,19.1z"></path>
</g>
</svg>
</span>
<span class="username desktop-only" aria-hidden="true" id="uname_short"></span>
<span class="sr-only">Show account info</span>
</button>
</div>
<div class="ncbi-popup-anchor">
<div class="ncbi-popup account-popup" id="account_popup" aria-hidden="true">
<div class="ncbi-popup-head">
<button class="ncbi-close-button" data-ga-action="close_menu" data-ga-label="account_menu" type="button">
<span class="fa fa-times">
<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 48 48" width="24px" height="24px">
<path d="M38 12.83l-2.83-2.83-11.17 11.17-11.17-11.17-2.83 2.83 11.17 11.17-11.17 11.17 2.83 2.83 11.17-11.17 11.17 11.17 2.83-2.83-11.17-11.17z"></path>
</svg>
</span>
<span class="usa-sr-only">Close</span></button>
<h4>Account</h4>
</div>
<div class="account-user-info">
Logged in as:<br />
<b><span class="username" id="uname_long">username</span></b>
</div>
<div class="account-links">
<ul class="usa-unstyled-list">
<li><a id="account_myncbi" href="/myncbi/" class="set-base-url" data-ga-action="click_menu_item" data-ga-label="account_myncbi">Dashboard</a></li>
<li><a id="account_pubs" href="/myncbi/collections/bibliography/" class="set-base-url" data-ga-action="click_menu_item" data-ga-label="account_pubs">Publications</a></li>
<li><a id="account_settings" href="/account/settings/" class="set-base-url" data-ga-action="click_menu_item" data-ga-label="account_settings">Account settings</a></li>
<li><a id="account_logout" href="/account/signout/" class="set-base-url" data-ga-action="click_menu_item" data-ga-label="account_logout">Log out</a></li>
</ul>
</div>
</div>
</div>
</div>
</div>
</header>
<div role="navigation" aria-label="access keys">
<a id="nws_header_accesskey_0" href="https://www.ncbi.nlm.nih.gov/guide/browsers/#ncbi_accesskeys" class="usa-sr-only" accesskey="0" tabindex="-1">Access keys</a>
<a id="nws_header_accesskey_1" href="https://www.ncbi.nlm.nih.gov" class="usa-sr-only" accesskey="1" tabindex="-1">NCBI Homepage</a>
<a id="nws_header_accesskey_2" href="/myncbi/" class="set-base-url usa-sr-only" accesskey="2" tabindex="-1">MyNCBI Homepage</a>
<a id="nws_header_accesskey_3" href="#maincontent" class="usa-sr-only" accesskey="3" tabindex="-1">Main Content</a>
<a id="nws_header_accesskey_4" href="#" class="usa-sr-only" accesskey="4" tabindex="-1">Main Navigation</a>
</div>
<section data-section="Alerts">
<div class="ncbi-alerts-placeholder"></div>
</section>
</div>
<div class="header">
<!-- logo -->
<div class="res_logo" id="gene-top">
<h1 class="res_name"><a href="/medgen">MedGen</a></h1>
<h2 class="res_tagline">National Center for Biotechnology Information</h2>
</div>
<!-- SearchBar -->
<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="medgen" selected="selected" data-ac_dict="medgen_disease_name">MedGen</option><option value="clinvar">ClinVar</option><option value="pubmed" data-ac_dict="pm_related_queries_2">PubMed</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene">Gene</option><option value="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen" data-ac_dict="medgen_disease_name">MedGen</option><option value="mesh" data-ac_dict="mesh_suggestions">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed" data-ac_dict="pm_related_queries_2">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search MedGen. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'medgen_disease_name',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a name="SaveSearch" title="Click to create an email alert for this search" href="/sites/myncbi/searches/save?db=medgen&amp;qk=45188" id="SaveSearch">Create alert</a></li><li><a sid="1" href="/medgen/limits">Limits</a></li><li><a href="/medgen/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/medgen/docs/help">Help</a></li></ul></div>
</div>
<input name="EntrezSystem2.PEntrez.MedGen.MedGen_PageController.PreviousPageName" sid="1" type="hidden" value="results" />
<div id="maincontent" class="col nine_col">
<div class="content">
<div>
</div>
<div class="results_settings one_setting"><ul class="inline_list left display_settings"><li><a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.Display">Full Report<span href="#" class="tgt_dark"></span></a></li></ul><div id="display_settings_menu_report" class="disp_settings tabPopper"><fieldset class="format"><legend>Format</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.sPresentation" sid="1" value="FullReport" format="" id="FullReport" checked="true" /><label for="FullReport">Full Report</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.sPresentation" sid="2" value="FullReport" format="text" id="FullReporttext" /><label for="FullReporttext">Summary (Text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.sPresentation" sid="3" value="XML" format="text" id="XMLtext" /><label for="XMLtext">Summary (XML)</label></li></ul></fieldset></div><button name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SetDisplay" sid="1" class="button_apply ncbipopper-close-button" style="display:none">Apply</button><h4 class="content_header send_to align_right jig-ncbipopper" id="sendto" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#send_to_menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, addCloseButton:true, groupName: 'entrez_pg', adjustFit:'none'"><a href="#" sourceContent="send_to_menu" class="tgt_dark">Send to:</a><script type="text/javascript">
jQuery(document).ready( function () {
jQuery("#send_to_menu input[type='radio']").click( function () {
var selectedValue = jQuery(this).val().toLowerCase();
var selectedDiv = jQuery("#send_to_menu div." + selectedValue);
if(selectedDiv.is(":hidden")){
jQuery("#send_to_menu div.submenu:visible").slideUp();
selectedDiv.slideDown();
}
});
});
jQuery("#sendto").bind("ncbipopperclose", function(){
jQuery("#send_to_menu div.submenu:visible").css("display","none");
jQuery("#send_to_menu input[type='radio']:checked").attr("checked",false);
});
</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.FFormat" sid="1"><option value="FullReport" format="text" selected="selected">Summary (Text)</option><option value="XML" format="text">Summary (XML)</option></select></li></ul><button name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.FileFormat" sid="1" type="hidden" value="FullReport" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.LastPresentation" sid="1" type="hidden" value="FullReport" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.Presentation" sid="1" type="hidden" value="FullReport" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PrevPresentation" sid="1" type="hidden" value="FullReport" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
<div class="">
<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
</div>
<div id="messagearea" class="empty">
</div>
<div><div class="rprt full-rprt"><div class="portlet" style="border-top-style: none; margin-top: 0px; padding-top: 0px; margin-bottom: 0px; padding-left: 0.2em;">
<!--
UID=854014
ConceptID=C3469524
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Prostate cancer susceptibility</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854014</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C3469524</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>PROSTATE CANCER, SUSCEPTIBILITY TO</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>OMIM<span class="superscript">®</span>:</td>
<td><a href="https://omim.org/entry/180435" target="_blank">180435</a>; <a href="https://omim.org/entry/313700" target="_blank">313700</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/24881167">Optimising the management of early prostate cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kirby R</span><br />
<span class="medgenPMjournal">Practitioner</span>
2014 Apr;258(1770):15-8, 2.
<span class="bold">PMID: </span><a href="/pubmed/24881167" target="_blank">24881167</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24203817">Cyclooxygenase 2 genotypes influence prostate cancer susceptibility in Japanese Men.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sugie S,
Tsukino H,
Mukai S,
Akioka T,
Shibata N,
Nagano M,
Kamoto T</span><br />
<span class="medgenPMjournal">Tumour Biol</span>
2014 Mar;35(3):2717-21.
Epub 2013 Nov 8
doi: 10.1007/s13277-013-1358-y.
<span class="bold">PMID: </span><a href="/pubmed/24203817" target="_blank">24203817</a></div>
<div class="nl"><a target="_blank" href="/pubmed/11838717">Interest in genetic prostate cancer susceptibility testing among african American men.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Weinrich S,
Royal C,
Pettaway CA,
Dunston G,
Faison-Smith L,
Priest JH,
Roberson-Smith P,
Frost J,
Jenkins J,
Brooks KA,
Powell I</span><br />
<span class="medgenPMjournal">Cancer Nurs</span>
2002 Feb;25(1):28-34.
doi: 10.1097/00002820-200202000-00007.
<span class="bold">PMID: </span><a href="/pubmed/11838717" target="_blank">11838717</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22prostate%20cancer%20susceptibility%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (12)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37945903">Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang A,
Shen J,
Rodriguez AA,
Saunders EJ,
Chen F,
Janivara R,
Darst BF,
Sheng X,
Xu Y,
Chou AJ,
Benlloch S,
Dadaev T,
Brook MN,
Plym A,
Sahimi A,
Hoffman TJ,
Takahashi A,
Matsuda K,
Momozawa Y,
Fujita M,
Laisk T,
Figuerêdo J,
Muir K,
Ito S,
Liu X;
Biobank Japan Project,
Uchio Y,
Kubo M,
Kamatani Y,
Lophatananon A,
Wan P,
Andrews C,
Lori A,
Choudhury PP,
Schleutker J,
Tammela TLJ,
Sipeky C,
Auvinen A,
Giles GG,
Southey MC,
MacInnis RJ,
Cybulski C,
Wokolorczyk D,
Lubinski J,
Rentsch CT,
Cho K,
Mcmahon BH,
Neal DE,
Donovan JL,
Hamdy FC,
Martin RM,
Nordestgaard BG,
Nielsen SF,
Weischer M,
Bojesen SE,
Røder A,
Stroomberg HV,
Batra J,
Chambers S,
Horvath L,
Clements JA,
Tilly W,
Risbridger GP,
Gronberg H,
Aly M,
Szulkin R,
Eklund M,
Nordstrom T,
Pashayan N,
Dunning AM,
Ghoussaini M,
Travis RC,
Key TJ,
Riboli E,
Park JY,
Sellers TA,
Lin HY,
Albanes D,
Weinstein S,
Cook MB,
Mucci LA,
Giovannucci E,
Lindstrom S,
Kraft P,
Hunter DJ,
Penney KL,
Turman C,
Tangen CM,
Goodman PJ,
Thompson IM Jr,
Hamilton RJ,
Fleshner NE,
Finelli A,
Parent MÉ,
Stanford JL,
Ostrander EA,
Koutros S,
Beane Freeman LE,
Stampfer M,
Wolk A,
Håkansson N,
Andriole GL,
Hoover RN,
Machiela MJ,
Sørensen KD,
Borre M,
Blot WJ,
Zheng W,
Yeboah ED,
Mensah JE,
Lu YJ,
Zhang HW,
Feng N,
Mao X,
Wu Y,
Zhao SC,
Sun Z,
Thibodeau SN,
McDonnell SK,
Schaid DJ,
West CML,
Barnett G,
Maier C,
Schnoeller T,
Luedeke M,
Kibel AS,
Drake BF,
Cussenot O,
Cancel-Tassin G,
Menegaux F,
Truong T,
Koudou YA,
John EM,
Grindedal EM,
Maehle L,
Khaw KT,
Ingles SA,
Stern MC,
Vega A,
Gómez-Caamaño A,
Fachal L,
Rosenstein BS,
Kerns SL,
Ostrer H,
Teixeira MR,
Paulo P,
Brandão A,
Watya S,
Lubwama A,
Bensen JT,
Butler EN,
Mohler JL,
Taylor JA,
Kogevinas M,
Dierssen-Sotos T,
Castaño-Vinyals G,
Cannon-Albright L,
Teerlink CC,
Huff CD,
Pilie P,
Yu Y,
Bohlender RJ,
Gu J,
Strom SS,
Multigner L,
Blanchet P,
Brureau L,
Kaneva R,
Slavov C,
Mitev V,
Leach RJ,
Brenner H,
Chen X,
Holleczek B,
Schöttker B,
Klein EA,
Hsing AW,
Kittles RA,
Murphy AB,
Logothetis CJ,
Kim J,
Neuhausen SL,
Steele L,
Ding YC,
Isaacs WB,
Nemesure B,
Hennis AJM,
Carpten J,
Pandha H,
Michael A,
De Ruyck K,
De Meerleer G,
Ost P,
Xu J,
Razack A,
Lim J,
Teo SH,
Newcomb LF,
Lin DW,
Fowke JH,
Neslund-Dudas CM,
Rybicki BA,
Gamulin M,
Lessel D,
Kulis T,
Usmani N,
Abraham A,
Singhal S,
Parliament M,
Claessens F,
Joniau S,
Van den Broeck T,
Gago-Dominguez M,
Castelao JE,
Martinez ME,
Larkin S,
Townsend PA,
Aukim-Hastie C,
Bush WS,
Aldrich MC,
Crawford DC,
Srivastava S,
Cullen J,
Petrovics G,
Casey G,
Wang Y,
Tettey Y,
Lachance J,
Tang W,
Biritwum RB,
Adjei AA,
Tay E,
Truelove A,
Niwa S,
Yamoah K,
Govindasami K,
Chokkalingam AP,
Keaton JM,
Hellwege JN,
Clark PE,
Jalloh M,
Gueye SM,
Niang L,
Ogunbiyi O,
Shittu O,
Amodu O,
Adebiyi AO,
Aisuodionoe-Shadrach OI,
Ajibola HO,
Jamda MA,
Oluwole OP,
Nwegbu M,
Adusei B,
Mante S,
Darkwa-Abrahams A,
Diop H,
Gundell SM,
Roobol MJ,
Jenster G,
van Schaik RHN,
Hu JJ,
Sanderson M,
Kachuri L,
Varma R,
McKean-Cowdin R,
Torres M,
Preuss MH,
Loos RJF,
Zawistowski M,
Zöllner S,
Lu Z,
Van Den Eeden SK,
Easton DF,
Ambs S,
Edwards TL,
Mägi R,
Rebbeck TR,
Fritsche L,
Chanock SJ,
Berndt SI,
Wiklund F,
Nakagawa H,
Witte JS,
Gaziano JM,
Justice AC,
Mancuso N,
Terao C,
Eeles RA,
Kote-Jarai Z,
Madduri RK,
Conti DV,
Haiman CA</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2023 Dec;55(12):2065-2074.
Epub 2023 Nov 9
doi: 10.1038/s41588-023-01534-4.
<span class="bold">PMID: </span><a href="/pubmed/37945903" target="_blank">37945903</a><a href="/pmc/articles/PMC10841479" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34560228">Mechanistic insights into genetic susceptibility to prostate cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tian P,
Zhong M,
Wei GH</span><br />
<span class="medgenPMjournal">Cancer Lett</span>
2021 Dec 1;522:155-163.
Epub 2021 Sep 22
doi: 10.1016/j.canlet.2021.09.025.
<span class="bold">PMID: </span><a href="/pubmed/34560228" target="_blank">34560228</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30033361">Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gao P,
Xia JH,
Sipeky C,
Dong XM,
Zhang Q,
Yang Y,
Zhang P,
Cruz SP,
Zhang K,
Zhu J,
Lee HM,
Suleman S,
Giannareas N,
Liu S;
PRACTICAL Consortium,
Tammela TLJ,
Auvinen A,
Wang X,
Huang Q,
Wang L,
Manninen A,
Vaarala MH,
Wang L,
Schleutker J,
Wei GH</span><br />
<span class="medgenPMjournal">Cell</span>
2018 Jul 26;174(3):576-589.e18.
Epub 2018 Jul 19
doi: 10.1016/j.cell.2018.06.003.
<span class="bold">PMID: </span><a href="/pubmed/30033361" target="_blank">30033361</a><a href="/pmc/articles/PMC6091222" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29892016">Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schumacher FR,
Al Olama AA,
Berndt SI,
Benlloch S,
Ahmed M,
Saunders EJ,
Dadaev T,
Leongamornlert D,
Anokian E,
Cieza-Borrella C,
Goh C,
Brook MN,
Sheng X,
Fachal L,
Dennis J,
Tyrer J,
Muir K,
Lophatananon A,
Stevens VL,
Gapstur SM,
Carter BD,
Tangen CM,
Goodman PJ,
Thompson IM Jr,
Batra J,
Chambers S,
Moya L,
Clements J,
Horvath L,
Tilley W,
Risbridger GP,
Gronberg H,
Aly M,
Nordström T,
Pharoah P,
Pashayan N,
Schleutker J,
Tammela TLJ,
Sipeky C,
Auvinen A,
Albanes D,
Weinstein S,
Wolk A,
Håkansson N,
West CML,
Dunning AM,
Burnet N,
Mucci LA,
Giovannucci E,
Andriole GL,
Cussenot O,
Cancel-Tassin G,
Koutros S,
Beane Freeman LE,
Sorensen KD,
Orntoft TF,
Borre M,
Maehle L,
Grindedal EM,
Neal DE,
Donovan JL,
Hamdy FC,
Martin RM,
Travis RC,
Key TJ,
Hamilton RJ,
Fleshner NE,
Finelli A,
Ingles SA,
Stern MC,
Rosenstein BS,
Kerns SL,
Ostrer H,
Lu YJ,
Zhang HW,
Feng N,
Mao X,
Guo X,
Wang G,
Sun Z,
Giles GG,
Southey MC,
MacInnis RJ,
FitzGerald LM,
Kibel AS,
Drake BF,
Vega A,
Gómez-Caamaño A,
Szulkin R,
Eklund M,
Kogevinas M,
Llorca J,
Castaño-Vinyals G,
Penney KL,
Stampfer M,
Park JY,
Sellers TA,
Lin HY,
Stanford JL,
Cybulski C,
Wokolorczyk D,
Lubinski J,
Ostrander EA,
Geybels MS,
Nordestgaard BG,
Nielsen SF,
Weischer M,
Bisbjerg R,
Røder MA,
Iversen P,
Brenner H,
Cuk K,
Holleczek B,
Maier C,
Luedeke M,
Schnoeller T,
Kim J,
Logothetis CJ,
John EM,
Teixeira MR,
Paulo P,
Cardoso M,
Neuhausen SL,
Steele L,
Ding YC,
De Ruyck K,
De Meerleer G,
Ost P,
Razack A,
Lim J,
Teo SH,
Lin DW,
Newcomb LF,
Lessel D,
Gamulin M,
Kulis T,
Kaneva R,
Usmani N,
Singhal S,
Slavov C,
Mitev V,
Parliament M,
Claessens F,
Joniau S,
Van den Broeck T,
Larkin S,
Townsend PA,
Aukim-Hastie C,
Gago-Dominguez M,
Castelao JE,
Martinez ME,
Roobol MJ,
Jenster G,
van Schaik RHN,
Menegaux F,
Truong T,
Koudou YA,
Xu J,
Khaw KT,
Cannon-Albright L,
Pandha H,
Michael A,
Thibodeau SN,
McDonnell SK,
Schaid DJ,
Lindstrom S,
Turman C,
Ma J,
Hunter DJ,
Riboli E,
Siddiq A,
Canzian F,
Kolonel LN,
Le Marchand L,
Hoover RN,
Machiela MJ,
Cui Z,
Kraft P,
Amos CI,
Conti DV,
Easton DF,
Wiklund F,
Chanock SJ,
Henderson BE,
Kote-Jarai Z,
Haiman CA,
Eeles RA;
Profile Study;
Australian Prostate Cancer BioResource (APCB);
IMPACT Study;
Canary PASS Investigators;
Breast and Prostate Cancer Cohort Consortium (BPC3);
PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium;
Cancer of the Prostate in Sweden (CAPS);
Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS);
Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2018 Jul;50(7):928-936.
Epub 2018 Jun 11
doi: 10.1038/s41588-018-0142-8.
<span class="bold">PMID: </span><a href="/pubmed/29892016" target="_blank">29892016</a><a href="/pmc/articles/PMC6568012" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23608167">Association of prostate cancer susceptibility variant (MSMB) rs10993994 with risk of spermatogenic failure.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wu W,
Lu J,
Yuan B,
Qin Y,
Chen M,
Niu X,
Xu B,
Lu C,
Xia Y,
Chen D,
Sha J,
Wang X</span><br />
<span class="medgenPMjournal">Gene</span>
2013 Jul 25;524(2):197-202.
Epub 2013 Apr 19
doi: 10.1016/j.gene.2013.03.142.
<span class="bold">PMID: </span><a href="/pubmed/23608167" target="_blank">23608167</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Prostate%20cancer%20susceptibility%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (346)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/39505858">A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Srinivasan S,
Kryza T,
Bock N,
Tse BWC,
Sokolowski KA,
Janaththani P,
Fernando A,
Moya L,
Stephens C,
Dong Y,
Röhl J,
Alinezhad S,
Vela I,
Perry-Keene JL,
Buzacott K,
Nica R;
IMPACT Study,
Gago-Dominguez M;
PROFILE Study Steering Committee,
Schleutker J,
Maier C,
Muir K,
Tangen CM,
Gronberg H,
Pashayan N,
Albanes D,
Wolk A,
Stanford JL,
Berndt SI,
Mucci LA,
Koutros S,
Cussenot O,
Sorensen KD,
Grindedal EM,
Travis RC,
Haiman CA,
MacInnis RJ,
Vega A,
Wiklund F,
Neal DE,
Kogevinas M,
Penney KL,
Nordestgaard BG,
Brenner H,
John EM,
Gamulin M,
Claessens F,
Melander O,
Dahlin A,
Stattin P,
Hallmans G,
Häggström C,
Johansson R,
Thysell E,
Rönn AC,
Li W,
Brown N,
Dimeski G,
Shepherd B,
Dadaev T,
Brook MN,
Spurdle AB,
Stenman UH,
Koistinen H,
Kote-Jarai Z,
Klein RJ,
Lilja H,
Ecker RC,
Eeles R;
Practical Consortium;
Australian Prostate Cancer BioResource,
Clements J,
Batra J</span><br />
<span class="medgenPMjournal">Nat Commun</span>
2024 Nov 6;15(1):9587.
doi: 10.1038/s41467-024-52472-6.
<span class="bold">PMID: </span><a href="/pubmed/39505858" target="_blank">39505858</a><a href="/pmc/articles/PMC11541583" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34863587">Inherited TP53 Variants and Risk of Prostate Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maxwell KN,
Cheng HH,
Powers J,
Gulati R,
Ledet EM,
Morrison C,
Le A,
Hausler R,
Stopfer J,
Hyman S,
Kohlmann W,
Naumer A,
Vagher J,
Greenberg SE,
Naylor L,
Laurino M,
Konnick EQ,
Shirts BH,
AlDubayan SH,
Van Allen EM,
Nguyen B,
Vijai J,
Abida W,
Carlo MI,
Dubard-Gault M,
Lee DJ,
Maese LD,
Mandelker D,
Montgomery B,
Morris MJ,
Nicolosi P,
Nussbaum RL,
Schwartz LE,
Stadler Z,
Garber JE,
Offit K,
Schiffman JD,
Nelson PS,
Sartor O,
Walsh MF,
Pritchard CC</span><br />
<span class="medgenPMjournal">Eur Urol</span>
2022 Mar;81(3):243-250.
Epub 2021 Dec 1
doi: 10.1016/j.eururo.2021.10.036.
<span class="bold">PMID: </span><a href="/pubmed/34863587" target="_blank">34863587</a><a href="/pmc/articles/PMC8891030" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34799695">The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Na R,
Wei J,
Sample CJ,
Gielzak M,
Choi S,
Cooney KA,
Rabizadeh D,
Walsh PC,
Zheng LS,
Xu J,
Isaacs WB</span><br />
<span class="medgenPMjournal">Br J Cancer</span>
2022 Mar;126(5):791-796.
Epub 2021 Nov 19
doi: 10.1038/s41416-021-01622-4.
<span class="bold">PMID: </span><a href="/pubmed/34799695" target="_blank">34799695</a><a href="/pmc/articles/PMC8888559" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33486571">Genetic predisposition to prostate cancer: an update.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ni Raghallaigh H,
Eeles R</span><br />
<span class="medgenPMjournal">Fam Cancer</span>
2022 Jan;21(1):101-114.
Epub 2021 Jan 24
doi: 10.1007/s10689-021-00227-3.
<span class="bold">PMID: </span><a href="/pubmed/33486571" target="_blank">33486571</a><a href="/pmc/articles/PMC8799539" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12790786">Prostate cancer susceptibility genes: lessons learned and challenges posed.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Simard J,
Dumont M,
Labuda D,
Sinnett D,
Meloche C,
El-Alfy M,
Berger L,
Lees E,
Labrie F,
Tavtigian SV</span><br />
<span class="medgenPMjournal">Endocr Relat Cancer</span>
2003 Jun;10(2):225-59.
doi: 10.1677/erc.0.0100225.
<span class="bold">PMID: </span><a href="/pubmed/12790786" target="_blank">12790786</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Prostate%20cancer%20susceptibility%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (134)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/37670334">Genetic polymorphisms of CYP24A1 gene and cancer susceptibility: a meta-analysis including 40640 subjects.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
Wang R,
Yuan S,
Liu X</span><br />
<span class="medgenPMjournal">World J Surg Oncol</span>
2023 Sep 5;21(1):279.
doi: 10.1186/s12957-023-03156-w.
<span class="bold">PMID: </span><a href="/pubmed/37670334" target="_blank">37670334</a><a href="/pmc/articles/PMC10478352" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30550272">Bacterial Resistance and Prostate Cancer Susceptibility Toward Metal-Ion-doped DNA Complexes.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vellampatti S,
Chandrasekaran G,
Mitta SB,
Dugasani SR,
Lakshmanan VK,
Park SH</span><br />
<span class="medgenPMjournal">ACS Appl Mater Interfaces</span>
2018 Dec 26;10(51):44290-44300.
Epub 2018 Dec 14
doi: 10.1021/acsami.8b17013.
<span class="bold">PMID: </span><a href="/pubmed/30550272" target="_blank">30550272</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28279145">Shorter GGN Repeats in Androgen Receptor Gene Would Not Increase the Risk of Prostate Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li J,
Xiao F,
Zhang Y,
Lan A,
Song Q,
Zhang R,
Gu K,
Chen P,
Li Z,
Zhang X,
Yang X</span><br />
<span class="medgenPMjournal">Technol Cancer Res Treat</span>
2017 Apr;16(2):159-166.
Epub 2016 Oct 17
doi: 10.1177/1533034616673272.
<span class="bold">PMID: </span><a href="/pubmed/28279145" target="_blank">28279145</a><a href="/pmc/articles/PMC5616035" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23593118">Genetic susceptibility loci, pesticide exposure and prostate cancer risk.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Koutros S,
Berndt SI,
Hughes Barry K,
Andreotti G,
Hoppin JA,
Sandler DP,
Yeager M,
Burdett LA,
Yuenger J,
Alavanja MC,
Beane Freeman LE</span><br />
<span class="medgenPMjournal">PLoS One</span>
2013;8(4):e58195.
Epub 2013 Apr 4
doi: 10.1371/journal.pone.0058195.
<span class="bold">PMID: </span><a href="/pubmed/23593118" target="_blank">23593118</a><a href="/pmc/articles/PMC3617165" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10453275">Diet, androgens, oxidative stress and prostate cancer susceptibility.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fleshner NE,
Klotz LH</span><br />
<span class="medgenPMjournal">Cancer Metastasis Rev</span>
1998-1999;17(4):325-30.
doi: 10.1023/a:1006118628183.
<span class="bold">PMID: </span><a href="/pubmed/10453275" target="_blank">10453275</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Prostate%20cancer%20susceptibility%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (29)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37670334">Genetic polymorphisms of CYP24A1 gene and cancer susceptibility: a meta-analysis including 40640 subjects.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
Wang R,
Yuan S,
Liu X</span><br />
<span class="medgenPMjournal">World J Surg Oncol</span>
2023 Sep 5;21(1):279.
doi: 10.1186/s12957-023-03156-w.
<span class="bold">PMID: </span><a href="/pubmed/37670334" target="_blank">37670334</a><a href="/pmc/articles/PMC10478352" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30033361">Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gao P,
Xia JH,
Sipeky C,
Dong XM,
Zhang Q,
Yang Y,
Zhang P,
Cruz SP,
Zhang K,
Zhu J,
Lee HM,
Suleman S,
Giannareas N,
Liu S;
PRACTICAL Consortium,
Tammela TLJ,
Auvinen A,
Wang X,
Huang Q,
Wang L,
Manninen A,
Vaarala MH,
Wang L,
Schleutker J,
Wei GH</span><br />
<span class="medgenPMjournal">Cell</span>
2018 Jul 26;174(3):576-589.e18.
Epub 2018 Jul 19
doi: 10.1016/j.cell.2018.06.003.
<span class="bold">PMID: </span><a href="/pubmed/30033361" target="_blank">30033361</a><a href="/pmc/articles/PMC6091222" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29892016">Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schumacher FR,
Al Olama AA,
Berndt SI,
Benlloch S,
Ahmed M,
Saunders EJ,
Dadaev T,
Leongamornlert D,
Anokian E,
Cieza-Borrella C,
Goh C,
Brook MN,
Sheng X,
Fachal L,
Dennis J,
Tyrer J,
Muir K,
Lophatananon A,
Stevens VL,
Gapstur SM,
Carter BD,
Tangen CM,
Goodman PJ,
Thompson IM Jr,
Batra J,
Chambers S,
Moya L,
Clements J,
Horvath L,
Tilley W,
Risbridger GP,
Gronberg H,
Aly M,
Nordström T,
Pharoah P,
Pashayan N,
Schleutker J,
Tammela TLJ,
Sipeky C,
Auvinen A,
Albanes D,
Weinstein S,
Wolk A,
Håkansson N,
West CML,
Dunning AM,
Burnet N,
Mucci LA,
Giovannucci E,
Andriole GL,
Cussenot O,
Cancel-Tassin G,
Koutros S,
Beane Freeman LE,
Sorensen KD,
Orntoft TF,
Borre M,
Maehle L,
Grindedal EM,
Neal DE,
Donovan JL,
Hamdy FC,
Martin RM,
Travis RC,
Key TJ,
Hamilton RJ,
Fleshner NE,
Finelli A,
Ingles SA,
Stern MC,
Rosenstein BS,
Kerns SL,
Ostrer H,
Lu YJ,
Zhang HW,
Feng N,
Mao X,
Guo X,
Wang G,
Sun Z,
Giles GG,
Southey MC,
MacInnis RJ,
FitzGerald LM,
Kibel AS,
Drake BF,
Vega A,
Gómez-Caamaño A,
Szulkin R,
Eklund M,
Kogevinas M,
Llorca J,
Castaño-Vinyals G,
Penney KL,
Stampfer M,
Park JY,
Sellers TA,
Lin HY,
Stanford JL,
Cybulski C,
Wokolorczyk D,
Lubinski J,
Ostrander EA,
Geybels MS,
Nordestgaard BG,
Nielsen SF,
Weischer M,
Bisbjerg R,
Røder MA,
Iversen P,
Brenner H,
Cuk K,
Holleczek B,
Maier C,
Luedeke M,
Schnoeller T,
Kim J,
Logothetis CJ,
John EM,
Teixeira MR,
Paulo P,
Cardoso M,
Neuhausen SL,
Steele L,
Ding YC,
De Ruyck K,
De Meerleer G,
Ost P,
Razack A,
Lim J,
Teo SH,
Lin DW,
Newcomb LF,
Lessel D,
Gamulin M,
Kulis T,
Kaneva R,
Usmani N,
Singhal S,
Slavov C,
Mitev V,
Parliament M,
Claessens F,
Joniau S,
Van den Broeck T,
Larkin S,
Townsend PA,
Aukim-Hastie C,
Gago-Dominguez M,
Castelao JE,
Martinez ME,
Roobol MJ,
Jenster G,
van Schaik RHN,
Menegaux F,
Truong T,
Koudou YA,
Xu J,
Khaw KT,
Cannon-Albright L,
Pandha H,
Michael A,
Thibodeau SN,
McDonnell SK,
Schaid DJ,
Lindstrom S,
Turman C,
Ma J,
Hunter DJ,
Riboli E,
Siddiq A,
Canzian F,
Kolonel LN,
Le Marchand L,
Hoover RN,
Machiela MJ,
Cui Z,
Kraft P,
Amos CI,
Conti DV,
Easton DF,
Wiklund F,
Chanock SJ,
Henderson BE,
Kote-Jarai Z,
Haiman CA,
Eeles RA;
Profile Study;
Australian Prostate Cancer BioResource (APCB);
IMPACT Study;
Canary PASS Investigators;
Breast and Prostate Cancer Cohort Consortium (BPC3);
PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium;
Cancer of the Prostate in Sweden (CAPS);
Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS);
Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2018 Jul;50(7):928-936.
Epub 2018 Jun 11
doi: 10.1038/s41588-018-0142-8.
<span class="bold">PMID: </span><a href="/pubmed/29892016" target="_blank">29892016</a><a href="/pmc/articles/PMC6568012" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26950096">Gene regulatory mechanisms underpinning prostate cancer susceptibility.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Whitington T,
Gao P,
Song W,
Ross-Adams H,
Lamb AD,
Yang Y,
Svezia I,
Klevebring D,
Mills IG,
Karlsson R,
Halim S,
Dunning MJ,
Egevad L,
Warren AY,
Neal DE,
Grönberg H,
Lindberg J,
Wei GH,
Wiklund F</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2016 Apr;48(4):387-97.
Epub 2016 Mar 7
doi: 10.1038/ng.3523.
<span class="bold">PMID: </span><a href="/pubmed/26950096" target="_blank">26950096</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9989206">Genetic epidemiology of prostate cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Narod S</span><br />
<span class="medgenPMjournal">Biochim Biophys Acta</span>
1999 Jan 29;1423(1):F1-13.
doi: 10.1016/s0304-419x(98)00030-4.
<span class="bold">PMID: </span><a href="/pubmed/9989206" target="_blank">9989206</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Prostate%20cancer%20susceptibility%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (92)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37945903">Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang A,
Shen J,
Rodriguez AA,
Saunders EJ,
Chen F,
Janivara R,
Darst BF,
Sheng X,
Xu Y,
Chou AJ,
Benlloch S,
Dadaev T,
Brook MN,
Plym A,
Sahimi A,
Hoffman TJ,
Takahashi A,
Matsuda K,
Momozawa Y,
Fujita M,
Laisk T,
Figuerêdo J,
Muir K,
Ito S,
Liu X;
Biobank Japan Project,
Uchio Y,
Kubo M,
Kamatani Y,
Lophatananon A,
Wan P,
Andrews C,
Lori A,
Choudhury PP,
Schleutker J,
Tammela TLJ,
Sipeky C,
Auvinen A,
Giles GG,
Southey MC,
MacInnis RJ,
Cybulski C,
Wokolorczyk D,
Lubinski J,
Rentsch CT,
Cho K,
Mcmahon BH,
Neal DE,
Donovan JL,
Hamdy FC,
Martin RM,
Nordestgaard BG,
Nielsen SF,
Weischer M,
Bojesen SE,
Røder A,
Stroomberg HV,
Batra J,
Chambers S,
Horvath L,
Clements JA,
Tilly W,
Risbridger GP,
Gronberg H,
Aly M,
Szulkin R,
Eklund M,
Nordstrom T,
Pashayan N,
Dunning AM,
Ghoussaini M,
Travis RC,
Key TJ,
Riboli E,
Park JY,
Sellers TA,
Lin HY,
Albanes D,
Weinstein S,
Cook MB,
Mucci LA,
Giovannucci E,
Lindstrom S,
Kraft P,
Hunter DJ,
Penney KL,
Turman C,
Tangen CM,
Goodman PJ,
Thompson IM Jr,
Hamilton RJ,
Fleshner NE,
Finelli A,
Parent MÉ,
Stanford JL,
Ostrander EA,
Koutros S,
Beane Freeman LE,
Stampfer M,
Wolk A,
Håkansson N,
Andriole GL,
Hoover RN,
Machiela MJ,
Sørensen KD,
Borre M,
Blot WJ,
Zheng W,
Yeboah ED,
Mensah JE,
Lu YJ,
Zhang HW,
Feng N,
Mao X,
Wu Y,
Zhao SC,
Sun Z,
Thibodeau SN,
McDonnell SK,
Schaid DJ,
West CML,
Barnett G,
Maier C,
Schnoeller T,
Luedeke M,
Kibel AS,
Drake BF,
Cussenot O,
Cancel-Tassin G,
Menegaux F,
Truong T,
Koudou YA,
John EM,
Grindedal EM,
Maehle L,
Khaw KT,
Ingles SA,
Stern MC,
Vega A,
Gómez-Caamaño A,
Fachal L,
Rosenstein BS,
Kerns SL,
Ostrer H,
Teixeira MR,
Paulo P,
Brandão A,
Watya S,
Lubwama A,
Bensen JT,
Butler EN,
Mohler JL,
Taylor JA,
Kogevinas M,
Dierssen-Sotos T,
Castaño-Vinyals G,
Cannon-Albright L,
Teerlink CC,
Huff CD,
Pilie P,
Yu Y,
Bohlender RJ,
Gu J,
Strom SS,
Multigner L,
Blanchet P,
Brureau L,
Kaneva R,
Slavov C,
Mitev V,
Leach RJ,
Brenner H,
Chen X,
Holleczek B,
Schöttker B,
Klein EA,
Hsing AW,
Kittles RA,
Murphy AB,
Logothetis CJ,
Kim J,
Neuhausen SL,
Steele L,
Ding YC,
Isaacs WB,
Nemesure B,
Hennis AJM,
Carpten J,
Pandha H,
Michael A,
De Ruyck K,
De Meerleer G,
Ost P,
Xu J,
Razack A,
Lim J,
Teo SH,
Newcomb LF,
Lin DW,
Fowke JH,
Neslund-Dudas CM,
Rybicki BA,
Gamulin M,
Lessel D,
Kulis T,
Usmani N,
Abraham A,
Singhal S,
Parliament M,
Claessens F,
Joniau S,
Van den Broeck T,
Gago-Dominguez M,
Castelao JE,
Martinez ME,
Larkin S,
Townsend PA,
Aukim-Hastie C,
Bush WS,
Aldrich MC,
Crawford DC,
Srivastava S,
Cullen J,
Petrovics G,
Casey G,
Wang Y,
Tettey Y,
Lachance J,
Tang W,
Biritwum RB,
Adjei AA,
Tay E,
Truelove A,
Niwa S,
Yamoah K,
Govindasami K,
Chokkalingam AP,
Keaton JM,
Hellwege JN,
Clark PE,
Jalloh M,
Gueye SM,
Niang L,
Ogunbiyi O,
Shittu O,
Amodu O,
Adebiyi AO,
Aisuodionoe-Shadrach OI,
Ajibola HO,
Jamda MA,
Oluwole OP,
Nwegbu M,
Adusei B,
Mante S,
Darkwa-Abrahams A,
Diop H,
Gundell SM,
Roobol MJ,
Jenster G,
van Schaik RHN,
Hu JJ,
Sanderson M,
Kachuri L,
Varma R,
McKean-Cowdin R,
Torres M,
Preuss MH,
Loos RJF,
Zawistowski M,
Zöllner S,
Lu Z,
Van Den Eeden SK,
Easton DF,
Ambs S,
Edwards TL,
Mägi R,
Rebbeck TR,
Fritsche L,
Chanock SJ,
Berndt SI,
Wiklund F,
Nakagawa H,
Witte JS,
Gaziano JM,
Justice AC,
Mancuso N,
Terao C,
Eeles RA,
Kote-Jarai Z,
Madduri RK,
Conti DV,
Haiman CA</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2023 Dec;55(12):2065-2074.
Epub 2023 Nov 9
doi: 10.1038/s41588-023-01534-4.
<span class="bold">PMID: </span><a href="/pubmed/37945903" target="_blank">37945903</a><a href="/pmc/articles/PMC10841479" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34863587">Inherited TP53 Variants and Risk of Prostate Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maxwell KN,
Cheng HH,
Powers J,
Gulati R,
Ledet EM,
Morrison C,
Le A,
Hausler R,
Stopfer J,
Hyman S,
Kohlmann W,
Naumer A,
Vagher J,
Greenberg SE,
Naylor L,
Laurino M,
Konnick EQ,
Shirts BH,
AlDubayan SH,
Van Allen EM,
Nguyen B,
Vijai J,
Abida W,
Carlo MI,
Dubard-Gault M,
Lee DJ,
Maese LD,
Mandelker D,
Montgomery B,
Morris MJ,
Nicolosi P,
Nussbaum RL,
Schwartz LE,
Stadler Z,
Garber JE,
Offit K,
Schiffman JD,
Nelson PS,
Sartor O,
Walsh MF,
Pritchard CC</span><br />
<span class="medgenPMjournal">Eur Urol</span>
2022 Mar;81(3):243-250.
Epub 2021 Dec 1
doi: 10.1016/j.eururo.2021.10.036.
<span class="bold">PMID: </span><a href="/pubmed/34863587" target="_blank">34863587</a><a href="/pmc/articles/PMC8891030" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34799695">The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Na R,
Wei J,
Sample CJ,
Gielzak M,
Choi S,
Cooney KA,
Rabizadeh D,
Walsh PC,
Zheng LS,
Xu J,
Isaacs WB</span><br />
<span class="medgenPMjournal">Br J Cancer</span>
2022 Mar;126(5):791-796.
Epub 2021 Nov 19
doi: 10.1038/s41416-021-01622-4.
<span class="bold">PMID: </span><a href="/pubmed/34799695" target="_blank">34799695</a><a href="/pmc/articles/PMC8888559" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33486571">Genetic predisposition to prostate cancer: an update.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ni Raghallaigh H,
Eeles R</span><br />
<span class="medgenPMjournal">Fam Cancer</span>
2022 Jan;21(1):101-114.
Epub 2021 Jan 24
doi: 10.1007/s10689-021-00227-3.
<span class="bold">PMID: </span><a href="/pubmed/33486571" target="_blank">33486571</a><a href="/pmc/articles/PMC8799539" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29892016">Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schumacher FR,
Al Olama AA,
Berndt SI,
Benlloch S,
Ahmed M,
Saunders EJ,
Dadaev T,
Leongamornlert D,
Anokian E,
Cieza-Borrella C,
Goh C,
Brook MN,
Sheng X,
Fachal L,
Dennis J,
Tyrer J,
Muir K,
Lophatananon A,
Stevens VL,
Gapstur SM,
Carter BD,
Tangen CM,
Goodman PJ,
Thompson IM Jr,
Batra J,
Chambers S,
Moya L,
Clements J,
Horvath L,
Tilley W,
Risbridger GP,
Gronberg H,
Aly M,
Nordström T,
Pharoah P,
Pashayan N,
Schleutker J,
Tammela TLJ,
Sipeky C,
Auvinen A,
Albanes D,
Weinstein S,
Wolk A,
Håkansson N,
West CML,
Dunning AM,
Burnet N,
Mucci LA,
Giovannucci E,
Andriole GL,
Cussenot O,
Cancel-Tassin G,
Koutros S,
Beane Freeman LE,
Sorensen KD,
Orntoft TF,
Borre M,
Maehle L,
Grindedal EM,
Neal DE,
Donovan JL,
Hamdy FC,
Martin RM,
Travis RC,
Key TJ,
Hamilton RJ,
Fleshner NE,
Finelli A,
Ingles SA,
Stern MC,
Rosenstein BS,
Kerns SL,
Ostrer H,
Lu YJ,
Zhang HW,
Feng N,
Mao X,
Guo X,
Wang G,
Sun Z,
Giles GG,
Southey MC,
MacInnis RJ,
FitzGerald LM,
Kibel AS,
Drake BF,
Vega A,
Gómez-Caamaño A,
Szulkin R,
Eklund M,
Kogevinas M,
Llorca J,
Castaño-Vinyals G,
Penney KL,
Stampfer M,
Park JY,
Sellers TA,
Lin HY,
Stanford JL,
Cybulski C,
Wokolorczyk D,
Lubinski J,
Ostrander EA,
Geybels MS,
Nordestgaard BG,
Nielsen SF,
Weischer M,
Bisbjerg R,
Røder MA,
Iversen P,
Brenner H,
Cuk K,
Holleczek B,
Maier C,
Luedeke M,
Schnoeller T,
Kim J,
Logothetis CJ,
John EM,
Teixeira MR,
Paulo P,
Cardoso M,
Neuhausen SL,
Steele L,
Ding YC,
De Ruyck K,
De Meerleer G,
Ost P,
Razack A,
Lim J,
Teo SH,
Lin DW,
Newcomb LF,
Lessel D,
Gamulin M,
Kulis T,
Kaneva R,
Usmani N,
Singhal S,
Slavov C,
Mitev V,
Parliament M,
Claessens F,
Joniau S,
Van den Broeck T,
Larkin S,
Townsend PA,
Aukim-Hastie C,
Gago-Dominguez M,
Castelao JE,
Martinez ME,
Roobol MJ,
Jenster G,
van Schaik RHN,
Menegaux F,
Truong T,
Koudou YA,
Xu J,
Khaw KT,
Cannon-Albright L,
Pandha H,
Michael A,
Thibodeau SN,
McDonnell SK,
Schaid DJ,
Lindstrom S,
Turman C,
Ma J,
Hunter DJ,
Riboli E,
Siddiq A,
Canzian F,
Kolonel LN,
Le Marchand L,
Hoover RN,
Machiela MJ,
Cui Z,
Kraft P,
Amos CI,
Conti DV,
Easton DF,
Wiklund F,
Chanock SJ,
Henderson BE,
Kote-Jarai Z,
Haiman CA,
Eeles RA;
Profile Study;
Australian Prostate Cancer BioResource (APCB);
IMPACT Study;
Canary PASS Investigators;
Breast and Prostate Cancer Cohort Consortium (BPC3);
PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium;
Cancer of the Prostate in Sweden (CAPS);
Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS);
Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2018 Jul;50(7):928-936.
Epub 2018 Jun 11
doi: 10.1038/s41588-018-0142-8.
<span class="bold">PMID: </span><a href="/pubmed/29892016" target="_blank">29892016</a><a href="/pmc/articles/PMC6568012" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Prostate%20cancer%20susceptibility%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (213)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/31686670">Evidence from 40 Studies that 2 Common Single-Nucleotide Polymorphisms (SNPs) of RNASEL Gene Affect Prostate Cancer Susceptibility: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-Compliant Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xia J,
Sun R</span><br />
<span class="medgenPMjournal">Med Sci Monit</span>
2019 Nov 5;25:8315-8325.
doi: 10.12659/MSM.917715.
<span class="bold">PMID: </span><a href="/pubmed/31686670" target="_blank">31686670</a><a href="/pmc/articles/PMC6857427" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27598322">Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Khankari NK,
Shu XO,
Wen W,
Kraft P,
Lindström S,
Peters U,
Schildkraut J,
Schumacher F,
Bofetta P,
Risch A,
Bickeböller H,
Amos CI,
Easton D,
Eeles RA,
Gruber SB,
Haiman CA,
Hunter DJ,
Chanock SJ,
Pierce BL,
Zheng W;
Colorectal Transdisciplinary Study (CORECT);
Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE);
Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE);
Transdisciplinary Research in Cancer of the Lung (TRICL)</span><br />
<span class="medgenPMjournal">PLoS Med</span>
2016 Sep;13(9):e1002118.
Epub 2016 Sep 6
doi: 10.1371/journal.pmed.1002118.
<span class="bold">PMID: </span><a href="/pubmed/27598322" target="_blank">27598322</a><a href="/pmc/articles/PMC5012582" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21715604">A systematic review of replication studies of prostate cancer susceptibility genetic variants in high-risk men originally identified from genome-wide association studies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ishak MB,
Giri VN</span><br />
<span class="medgenPMjournal">Cancer Epidemiol Biomarkers Prev</span>
2011 Aug;20(8):1599-610.
Epub 2011 Jun 29
doi: 10.1158/1055-9965.EPI-11-0312.
<span class="bold">PMID: </span><a href="/pubmed/21715604" target="_blank">21715604</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Prostate%20cancer%20susceptibility%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div></div>
</div>
</div></div></div></div></div></div></div>
<div id="messagearea_bottom">
</div>
<div class=" bottom">
</div>
</div>
</div>
<div class="supplemental col three_col last">
<h2 class="offscreen_noflow">Supplemental Content</h2>
<div>
<!-- MedGen supplemental column starts here -->
<div class="rightCol mgCol">
<div class="portlet mgSection" id="ID_113">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul id="my-toc"></ul></div>
</div>
<div class="portlet mgSection" id="ID_106">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C3469524%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (2)</a></li>
<li><a href="/gtr/tests?term=C3469524%5bDISCUI%5d&amp;filter=method%3A2%5F17" target="_blank">Mutation scanning of the entire coding region (1)</a></li>
<li><a href="/gtr/tests?term=C3469524%5bDISCUI%5d&amp;filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (1)</a></li>
<li><a href="/gtr/tests?term=C3469524%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (5)</a></li>
<li><a href="/gtr/tests?term=C3469524%5bDISCUI%5d&amp;filter=method%3A2%5F19" target="_blank">Targeted variant analysis (3)</a></li>
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C3469524%5bDISCUI%5d" target="_blank">See all (9)</a></total></li>
</ul></div>
</div>
<div class="portlet mgSection" id="ID_119">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Prostate%20cancer%20susceptibility" target="_blank">ClinicalTrials.gov</a></li></ul></div>
</div>
<div class="portlet mgSection" id="ID_121">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22prostate%20cancer%20susceptibility%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Prostate%20cancer%20susceptibility%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
</div>
<div class="portlet mgSection" id="ID_116">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&amp;query=Prostate%20cancer%20susceptibility" target="_blank">MedlinePlus</a></li></ul></div>
</div>
</div>
<div class="portlet brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Reviews</h3>
</div>
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="/pubmed/clinical?term=Prostate%20cancer%20susceptibility" ref="ncbi_uid=&amp;discoId=gtr_reviews&amp;linkpos=1&amp;linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
</li>
<li>
<a href="/pubmed?term=Prostate%20cancer%20susceptibility%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&amp;discoId=gtr_reviews&amp;linkpos=2&amp;linkpostotal=2" target="_blank">Reviews in PubMed</a>
</li>
</ul>
</div>
</div>
<!-- MedGen supplemental column ends here -->
<div class="portlet brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related information</h3>
</div>
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter"></a>
</div>
<div class="portlet_content DiscoveryDbLinks">
<ul>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=854014" ref="log$=recordlinks">ClinVar</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C3469524[DISCUI]" ref="log$=recordlinks">GTR</a>
<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C3469524[DISCUI]&amp;test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&amp;from_uid=854014" ref="log$=recordlinks">OMIM</a>
<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&amp;from_uid=854014" ref="log$=recordlinks">PMC Articles</a>
<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&amp;from_uid=854014" ref="log$=recordlinks">PubMed</a>
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed_omim&amp;from_uid=854014" ref="log$=recordlinks">PubMed (OMIM)</a>
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
</li>
</ul>
</div>
</div>
<div class="portlet">
<div class="portlet_head">
<div class="portlet_title">
<h3>Recent activity</h3>
</div>
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter"></a>
</div>
<div class="portlet_content">
<div id="HTDisplay" class="">
<input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
<div class="action">
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&amp;" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
Clear
</a>
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&amp;" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
Turn Off
</a>
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&amp;" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
Turn On
</a>
</div>
<ul id="activity">
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67cd3f5f84f3725e5908006c">Prostate cancer susceptibility</a>
<div class="ralinkpop offscreen_noflow">Prostate cancer susceptibility<div class="brieflinkpopdesc"></div></div>
<div class="tertiary">MedGen</div>
</li>
<li class="ra_qry two_line">
<a class="htb" ref="log$=activity&amp;linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67cd3f5db15b832ebccc4c62">C3469524[conceptid] <span class="number">(1)</span></a>
<div class="tertiary">MedGen</div>
</li>
<li class="ra_qry two_line">
<a class="htb" ref="log$=activity&amp;linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67cd3f5db15b832ebccc4896">C0268579[trait identifier] AND "OMIM"[submitter] <span class="number">(18)</span></a>
<div class="tertiary">ClinVar</div>
</li>
<li class="ra_qry two_line">
<a class="htb" ref="log$=activity&amp;linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67cd3f5bb15b832ebccc3bf9">C1839456[trait identifier] AND "OMIM"[submitter] <span class="number">(1)</span></a>
<div class="tertiary">ClinVar</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67cd3f5ab15b832ebccc38f0">Properdin deficiency, type III</a>
<div class="ralinkpop offscreen_noflow">Properdin deficiency, type III<div class="brieflinkpopdesc"></div></div>
<div class="tertiary">MedGen</div>
</li>
</ul>
<p class="HTOn">Your browsing activity is empty.</p>
<p class="HTOff">Activity recording is turned off.</p>
<p id="turnOn" class="HTOff">
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryOn" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryOn" cmd="HTOn" href="?cmd=HTOn&amp;" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryOn">Turn recording back on</a>
</p>
<a class="seemore" href="/sites/myncbi/recentactivity">See more...</a>
</div>
</div>
</div>
</div>
</div>
<div id="NCBIFooter_dynamic">
<!--<component id="NCBIBreadcrumbs"/>
<component id="NCBIHelpDesk"/>-->
<noscript><img alt="" src="/stat?jsdisabled=true&amp;ncbi_app=entrez&amp;ncbi_db=medgen&amp;ncbi_pdid=FullReport&amp;ncbi_phid=CE8D62247CD38DE10000000000520045" /></noscript>
</div>
<div xmlns="http://www.w3.org/1999/xhtml" class="footer" id="footer" xml:base="http://127.0.0.1/sites/static/header_footer/">
<section class="icon-section">
<div id="icon-section-header" class="icon-section_header">Follow NCBI</div>
<div class="grid-container container">
<div class="icon-section_container">
<a class="footer-icon" id="footer_twitter" href="https://twitter.com/ncbi" aria-label="Twitter">
<svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40" fill="none">
<title>Twitter</title>
<g id="twitterx1008">
<path id="path1008" d="M6.06736 7L16.8778 20.8991L6.00001 32.2H10.2L18.6 23.1L25.668 32.2H34L22.8 17.5L31.9 7H28.4L20.7 15.4L14.401 7H6.06898H6.06736ZM9.66753 8.73423H12.9327L29.7327 30.4658H26.5697L9.66753 8.73423Z" fill="#5B616B"></path>
</g>
</svg>
</a>
<a class="footer-icon" id="footer_facebook" href="https://www.facebook.com/ncbi.nlm" aria-label="Facebook"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
<title>Facebook</title>
<path class="cls-11" d="M210.5,115.12H171.74V97.82c0-8.14,5.39-10,9.19-10h27.14V52l-39.32-.12c-35.66,0-42.42,26.68-42.42,43.77v19.48H99.09v36.32h27.24v109h45.41v-109h35Z">
</path>
</svg></a>
<a class="footer-icon" id="footer_linkedin" href="https://www.linkedin.com/company/ncbinlm" aria-label="LinkedIn"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
<title>LinkedIn</title>
<path class="cls-11" d="M101.64,243.37H57.79v-114h43.85Zm-22-131.54h-.26c-13.25,0-21.82-10.36-21.82-21.76,0-11.65,8.84-21.15,22.33-21.15S101.7,78.72,102,90.38C102,101.77,93.4,111.83,79.63,111.83Zm100.93,52.61A17.54,17.54,0,0,0,163,182v61.39H119.18s.51-105.23,0-114H163v13a54.33,54.33,0,0,1,34.54-12.66c26,0,44.39,18.8,44.39,55.29v58.35H198.1V182A17.54,17.54,0,0,0,180.56,164.44Z">
</path>
</svg></a>
<a class="footer-icon" id="footer_github" href="https://github.com/ncbi" aria-label="GitHub"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
<defs>
<style>
.cls-11,
.cls-12 {
fill: #737373;
}
.cls-11 {
fill-rule: evenodd;
}
</style>
</defs>
<title>GitHub</title>
<path class="cls-11" d="M151.36,47.28a105.76,105.76,0,0,0-33.43,206.1c5.28,1,7.22-2.3,7.22-5.09,0-2.52-.09-10.85-.14-19.69-29.42,6.4-35.63-12.48-35.63-12.48-4.81-12.22-11.74-15.47-11.74-15.47-9.59-6.56.73-6.43.73-6.43,10.61.75,16.21,10.9,16.21,10.9,9.43,16.17,24.73,11.49,30.77,8.79,1-6.83,3.69-11.5,6.71-14.14C108.57,197.1,83.88,188,83.88,147.51a40.92,40.92,0,0,1,10.9-28.39c-1.1-2.66-4.72-13.42,1-28,0,0,8.88-2.84,29.09,10.84a100.26,100.26,0,0,1,53,0C198,88.3,206.9,91.14,206.9,91.14c5.76,14.56,2.14,25.32,1,28a40.87,40.87,0,0,1,10.89,28.39c0,40.62-24.74,49.56-48.29,52.18,3.79,3.28,7.17,9.71,7.17,19.58,0,14.15-.12,25.54-.12,29,0,2.82,1.9,6.11,7.26,5.07A105.76,105.76,0,0,0,151.36,47.28Z">
</path>
<path class="cls-12" d="M85.66,199.12c-.23.52-1.06.68-1.81.32s-1.2-1.06-.95-1.59,1.06-.69,1.82-.33,1.21,1.07.94,1.6Zm-1.3-1">
</path>
<path class="cls-12" d="M90,203.89c-.51.47-1.49.25-2.16-.49a1.61,1.61,0,0,1-.31-2.19c.52-.47,1.47-.25,2.17.49s.82,1.72.3,2.19Zm-1-1.08">
</path>
<path class="cls-12" d="M94.12,210c-.65.46-1.71,0-2.37-.91s-.64-2.07,0-2.52,1.7,0,2.36.89.65,2.08,0,2.54Zm0,0"></path>
<path class="cls-12" d="M99.83,215.87c-.58.64-1.82.47-2.72-.41s-1.18-2.06-.6-2.7,1.83-.46,2.74.41,1.2,2.07.58,2.7Zm0,0">
</path>
<path class="cls-12" d="M107.71,219.29c-.26.82-1.45,1.2-2.64.85s-2-1.34-1.74-2.17,1.44-1.23,2.65-.85,2,1.32,1.73,2.17Zm0,0">
</path>
<path class="cls-12" d="M116.36,219.92c0,.87-1,1.59-2.24,1.61s-2.29-.68-2.3-1.54,1-1.59,2.26-1.61,2.28.67,2.28,1.54Zm0,0">
</path>
<path class="cls-12" d="M124.42,218.55c.15.85-.73,1.72-2,1.95s-2.37-.3-2.52-1.14.73-1.75,2-2,2.37.29,2.53,1.16Zm0,0"></path>
</svg></a>
<a class="footer-icon" id="footer_blog" href="https://ncbiinsights.ncbi.nlm.nih.gov/" aria-label="Blog">
<svg xmlns="http://www.w3.org/2000/svg" id="Layer_1" data-name="Layer 1" viewBox="0 0 40 40">
<defs><style>.cls-1{fill:#737373;}</style></defs>
<title>NCBI Insights Blog</title>
<path class="cls-1" d="M14,30a4,4,0,1,1-4-4,4,4,0,0,1,4,4Zm11,3A19,19,0,0,0,7.05,15a1,1,0,0,0-1,1v3a1,1,0,0,0,.93,1A14,14,0,0,1,20,33.07,1,1,0,0,0,21,34h3a1,1,0,0,0,1-1Zm9,0A28,28,0,0,0,7,6,1,1,0,0,0,6,7v3a1,1,0,0,0,1,1A23,23,0,0,1,29,33a1,1,0,0,0,1,1h3A1,1,0,0,0,34,33Z"></path>
</svg>
</a>
</div>
</div>
</section>
<section class="container-fluid bg-primary">
<div class="container pt-5">
<div class="row mt-3">
<div class="col-lg-3 col-12">
<p><a class="text-white" href="https://www.nlm.nih.gov/socialmedia/index.html">Connect with NLM</a></p>
<ul class="list-inline social_media">
<li class="list-inline-item"><a href="https://twitter.com/NLM_NIH" aria-label="Twitter" target="_blank" rel="noopener noreferrer">
<svg xmlns="http://www.w3.org/2000/svg" width="35" height="35" viewBox="0 0 36 35" fill="none">
<title>Twitter</title>
<g id="twitterx1009" clip-path="url(#clip0_65276_3946)">
<path id="Vector_Twitter" d="M17.5006 34.6565C26.9761 34.6565 34.6575 26.9751 34.6575 17.4996C34.6575 8.02416 26.9761 0.342773 17.5006 0.342773C8.02514 0.342773 0.34375 8.02416 0.34375 17.4996C0.34375 26.9751 8.02514 34.6565 17.5006 34.6565Z" fill="#205493" stroke="white" stroke-width="1.0" stroke-miterlimit="10"></path>
<path id="path1009" d="M8.54811 8.5L16.2698 18.4279L8.50001 26.5H11.5L17.5 20L22.5486 26.5H28.5L20.5 16L27 8.5H24.5L19 14.5L14.5007 8.5H8.54927H8.54811ZM11.1197 9.73873H13.4519L25.4519 25.2613H23.1926L11.1197 9.73873Z" fill="white"></path>
</g>
<defs>
<clipPath id="clip0_65276_3946">
<rect width="35" height="35" fill="white"></rect>
</clipPath>
</defs>
</svg>
</a></li>
<li class="list-inline-item"><a href="https://www.facebook.com/nationallibraryofmedicine" aria-label="Facebook" rel="noopener noreferrer" target="_blank">
<svg xmlns="http://www.w3.org/2000/svg" width="35" height="35" viewBox="0 0 36 35" fill="none">
<title>Facebook</title>
<g id="Facebook" clip-path="url(#clip0_1717_1086)">
<path id="Vector_Facebook" d="M15.1147 29.1371C15.1147 29.0822 15.1147 29.0296 15.1147 28.9747V18.9414H11.8183C11.6719 18.9414 11.6719 18.9414 11.6719 18.8018C11.6719 17.5642 11.6719 16.3289 11.6719 15.0937C11.6719 14.9793 11.7062 14.9518 11.816 14.9518C12.8683 14.9518 13.9206 14.9518 14.9751 14.9518H15.1215V14.8329C15.1215 13.8057 15.1215 12.774 15.1215 11.7492C15.1274 10.9262 15.3148 10.1146 15.6706 9.37241C16.1301 8.38271 16.9475 7.60378 17.9582 7.19235C18.6492 6.90525 19.3923 6.76428 20.1405 6.7783C21.0029 6.79202 21.8653 6.83091 22.7278 6.86065C22.8879 6.86065 23.048 6.89496 23.2082 6.90182C23.2974 6.90182 23.3271 6.94071 23.3271 7.02993C23.3271 7.54235 23.3271 8.05477 23.3271 8.5649C23.3271 9.16882 23.3271 9.77274 23.3271 10.3767C23.3271 10.4819 23.2974 10.5139 23.1921 10.5116C22.5379 10.5116 21.8814 10.5116 21.2271 10.5116C20.9287 10.5184 20.6316 10.5528 20.3395 10.6146C20.0822 10.6619 19.8463 10.7891 19.6653 10.9779C19.4842 11.1668 19.3672 11.4078 19.3307 11.6669C19.2857 11.893 19.2612 12.1226 19.2575 12.3531C19.2575 13.1904 19.2575 14.0299 19.2575 14.8695C19.2575 14.8946 19.2575 14.9198 19.2575 14.9564H23.0229C23.1807 14.9564 23.183 14.9564 23.1624 15.1074C23.0778 15.7662 22.9885 16.425 22.9039 17.0816C22.8322 17.6321 22.7636 18.1827 22.698 18.7332C22.6729 18.9437 22.6797 18.9437 22.4693 18.9437H19.2644V28.8992C19.2644 28.9793 19.2644 29.0593 19.2644 29.1394L15.1147 29.1371Z" fill="white"></path>
<path id="Vector_2_Facebook" d="M17.5006 34.657C26.9761 34.657 34.6575 26.9756 34.6575 17.5001C34.6575 8.02465 26.9761 0.343262 17.5006 0.343262C8.02514 0.343262 0.34375 8.02465 0.34375 17.5001C0.34375 26.9756 8.02514 34.657 17.5006 34.657Z" stroke="white" stroke-width="1.0" stroke-miterlimit="10"></path>
</g>
<defs>
<clipPath id="clip0_1717_1086">
<rect width="35" height="35" fill="white"></rect>
</clipPath>
</defs>
</svg>
</a></li>
<li class="list-inline-item"><a href="https://www.youtube.com/user/NLMNIH" aria-label="Youtube" target="_blank" rel="noopener noreferrer">
<svg xmlns="http://www.w3.org/2000/svg" width="35" height="35" viewBox="0 0 36 35" fill="none">
<title>Youtube</title>
<g id="YouTube" clip-path="url(#clip0_1717_1101)">
<path id="Vector_Youtube" d="M26.2571 11.4791C25.9025 11.1589 25.5709 10.9576 24.228 10.834C22.5512 10.6785 20.2797 10.6556 18.564 10.6533H16.4365C14.7208 10.6533 12.4493 10.6785 10.7725 10.834C9.43196 10.9576 9.09798 11.1589 8.7434 11.4791C7.81464 12.321 7.6202 14.6268 7.59961 16.8938C7.59961 17.3178 7.59961 17.741 7.59961 18.1635C7.62706 20.4121 7.82837 22.686 8.7434 23.521C9.09798 23.8412 9.42967 24.0425 10.7725 24.1661C12.4493 24.3216 14.7208 24.3445 16.4365 24.3468H18.564C20.2797 24.3468 22.5512 24.3216 24.228 24.1661C25.5686 24.0425 25.9025 23.8412 26.2571 23.521C27.1722 22.6929 27.3735 20.451 27.4009 18.2206C27.4009 17.7402 27.4009 17.2599 27.4009 16.7795C27.3735 14.5491 27.1699 12.3072 26.2571 11.4791ZM15.5604 20.5311V14.652L20.561 17.5001L15.5604 20.5311Z" fill="white"></path>
<path id="Vector_2_Youtube" d="M17.5006 34.657C26.9761 34.657 34.6575 26.9756 34.6575 17.5001C34.6575 8.02465 26.9761 0.343262 17.5006 0.343262C8.02514 0.343262 0.34375 8.02465 0.34375 17.5001C0.34375 26.9756 8.02514 34.657 17.5006 34.657Z" stroke="white" stroke-width="1.0" stroke-miterlimit="10"></path>
</g>
<defs>
<clipPath id="clip0_1717_1101">
<rect width="35" height="35" fill="white"></rect>
</clipPath>
</defs>
</svg>
</a></li>
</ul>
</div>
<div class="col-lg-3 col-12">
<p class="address_footer text-white">National Library of Medicine<br />
<a href="https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/@38.9959508,-77.101021,17z/data=!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb:0x19156f88b27635b8!8m2!3d38.9959508!4d-77.0988323" class="text-white" target="_blank" rel="noopener noreferrer">8600 Rockville Pike<br />
Bethesda, MD 20894</a></p>
</div>
<div class="col-lg-3 col-12 centered-lg">
<p><a href="https://www.nlm.nih.gov/web_policies.html" class="text-white">Web Policies</a><br />
<a href="https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office" class="text-white">FOIA</a><br />
<a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" class="text-white" id="vdp">HHS Vulnerability Disclosure</a></p>
</div>
<div class="col-lg-3 col-12 centered-lg">
<p><a class="supportLink text-white" href="https://support.nlm.nih.gov/">Help</a><br />
<a href="https://www.nlm.nih.gov/accessibility.html" class="text-white">Accessibility</a><br />
<a href="https://www.nlm.nih.gov/careers/careers.html" class="text-white">Careers</a></p>
</div>
</div>
<div class="row">
<div class="col-lg-12 centered-lg">
<nav class="bottom-links">
<ul class="mt-3">
<li>
<a class="text-white" href="//www.nlm.nih.gov/">NLM</a>
</li>
<li>
<a class="text-white" href="https://www.nih.gov/">NIH</a>
</li>
<li>
<a class="text-white" href="https://www.hhs.gov/">HHS</a>
</li>
<li>
<a class="text-white" href="https://www.usa.gov/">USA.gov</a>
</li>
</ul>
</nav>
</div>
</div>
</div>
</section>
<script type="text/javascript" src="/portal/portal3rc.fcgi/rlib/js/InstrumentOmnitureBaseJS/InstrumentNCBIConfigJS/InstrumentNCBIBaseJS/InstrumentPageStarterJS.js?v=1"> </script>
<script type="text/javascript" src="/portal/portal3rc.fcgi/static/js/hfjs2.js"> </script>
</div>
</div>
<div><input name="EntrezSystem2.PEntrez.DbConnector.Db" sid="1" type="hidden" value="medgen" /><input name="EntrezSystem2.PEntrez.DbConnector.LastDb" sid="1" type="hidden" value="medgen" /><input name="EntrezSystem2.PEntrez.DbConnector.Term" sid="1" type="hidden" value="C3469524[conceptid]" /><input name="EntrezSystem2.PEntrez.DbConnector.LastTabCmd" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.DbConnector.LastQueryKey" sid="1" type="hidden" value="45188" /><input name="EntrezSystem2.PEntrez.DbConnector.IdsFromResult" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.DbConnector.LastIdsFromResult" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.DbConnector.LinkName" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.LinkReadableName" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.LinkSrcDb" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.Cmd" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.TabCmd" sid="1" type="hidden" /><input name="EntrezSystem2.PEntrez.DbConnector.QueryKey" sid="1" type="hidden" /></div>
<input type="hidden" name="p$a" id="p$a" /><input type="hidden" name="p$l" id="p$l" value="EntrezSystem2" /><input type="hidden" name="p$st" id="p$st" value="medgen" /><input name="SessionId" id="SessionId" value="CE8B5AF87C7FFCB1_0191SID" disabled="disabled" type="hidden" /><input name="Snapshot" id="Snapshot" value="/projects/Phenotype/MedGen/MedGen@6.14" disabled="disabled" type="hidden" /></form>
</div>
</div>
<!-- CE8B5AF87C7FFCB1_0191SID /projects/Phenotype/MedGen/MedGen@6.14 portal106 v4.1.r689238 Tue, Oct 22 2024 16:10:51 -->
<span id="portal-csrf-token" style="display:none" data-token="CE8B5AF87C7FFCB1_0191SID"></span>
<script type='text/javascript' src='/portal/js/portal.js'></script><script type="text/javascript" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/js/4221766/3812534/4212053/3812535/3781605/4186313/2499590/3758627/4078478/3908752/3423/4018706/3891418/4212356/4078480/4078479/4025341/4076482/31971/35962/2733373/33966/3397055/4001808.js" snapshot="medgen"></script></body>
</html>
Reference in a new issue View git blame Copy permalink