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<meta name="keywords" content="C3150693, autism 17, autism susceptibility 17, autism, susceptibility to, 17, autism, susceptibility to, type 17, auts17, finding, shank2, susceptibility to autism 17, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Autism, the prototypic pervasive developmental disorder (PDD), is usually apparent by 3 years of age. It is characterized by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypic, and ritualized patterns of interests and behavior (Bailey et al., 1996; Risch et al., 1999). 'Autism spectrum disorder,' sometimes referred to as ASD, is a broader phenotype encompassing the less severe disorders Asperger syndrome (see ASPG1; 608638) and pervasive developmental disorder, not otherwise specified (PDD-NOS). 'Broad autism phenotype' includes individuals with some symptoms of autism, but who do not meet the full criteria for autism or other disorders. Impaired intellectual development (IDD) coexists in approximately two-thirds of individuals with ASD, except for Asperger syndrome, in IDD is conspicuously absent (Jones et al., 2008). Genetic studies in autism often include family members with these less stringent diagnoses (Schellenberg et al., 2006). For a discussion of genetic heterogeneity of autism, see 209850." /><meta name="robots" content="index,nofollow,noarchive" />
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|
||
<!--
|
||
UID=462043
|
||
ConceptID=C3150693
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Autism, susceptibility to, 17<span class="h1sub">(AUTS17)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462043</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C3150693</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Autism 17; Autism susceptibility 17</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="SHANK2 - ID: 22941 - NCBI Gene" href="/gene/22941" class="medgenPMinfo">SHANK2</a> (11q13.3-13.4)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0013265" target="_blank">MONDO:0013265</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/613436" target="_blank">613436</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Autism, the prototypic pervasive developmental disorder (PDD), is usually apparent by 3 years of age. It is characterized by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypic, and ritualized patterns of interests and behavior (Bailey et al., 1996; Risch et al., 1999). 'Autism spectrum disorder,' sometimes referred to as ASD, is a broader phenotype encompassing the less severe disorders Asperger syndrome (see ASPG1; 608638) and pervasive developmental disorder, not otherwise specified (PDD-NOS). 'Broad autism phenotype' includes individuals with some symptoms of autism, but who do not meet the full criteria for autism or other disorders. Impaired intellectual development (IDD) coexists in approximately two-thirds of individuals with ASD, except for Asperger syndrome, in IDD is conspicuously absent (Jones et al., 2008). Genetic studies in autism often include family members with these less stringent diagnoses (Schellenberg et al., 2006). For a discussion of genetic heterogeneity of autism, see 209850. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33130809">Epilepsy, neuropsychiatric phenotypes, neuroimaging findings, and genotype-neurophenotype correlation in 22q11.2 deletion syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">AlKalaf HY,
|
||
AlHashem AM,
|
||
AlSaleh NS,
|
||
AlJohar NM,
|
||
Abo Thneen AM,
|
||
ElGhezal HM,
|
||
Bouhjar IB,
|
||
Tlili-Graiess K,
|
||
Sahari AH,
|
||
Tabarki BM</span><br />
|
||
<span class="medgenPMjournal">Neurosciences (Riyadh)</span>
|
||
2020 Aug;25(4):287-291.
|
||
doi: 10.17712/nsj.2020.4.20200045.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33130809" target="_blank">33130809</a><a href="/pmc/articles/PMC8015611" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32986108">Differential Associations of Apolipoprotein E ε4 Genotype With Attentional Abilities Across the Life Span of Individuals With Down Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">D'Souza H,
|
||
Mason L,
|
||
Mok KY,
|
||
Startin CM,
|
||
Hamburg S,
|
||
Hithersay R,
|
||
Baksh RA,
|
||
Hardy J,
|
||
Strydom A,
|
||
Thomas MSC;
|
||
London Down Syndrome (LonDownS) Consortium</span><br />
|
||
<span class="medgenPMjournal">JAMA Netw Open</span>
|
||
2020 Sep 1;3(9):e2018221.
|
||
doi: 10.1001/jamanetworkopen.2020.18221.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32986108" target="_blank">32986108</a><a href="/pmc/articles/PMC7522696" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31940763">Autism Spectrum Disorders: Prenatal Genetic Testing and Abortion Decision-Making among Taiwanese Mothers of Affected Children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen WJ,
|
||
Zhao S,
|
||
Huang TY,
|
||
Kwok OM,
|
||
Chen LS</span><br />
|
||
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
|
||
2020 Jan 11;17(2)
|
||
doi: 10.3390/ijerph17020476.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31940763" target="_blank">31940763</a><a href="/pmc/articles/PMC7013751" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(autism%2C%20susceptibility%20to%2C%2017)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33004838">Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang T,
|
||
Hoekzema K,
|
||
Vecchio D,
|
||
Wu H,
|
||
Sulovari A,
|
||
Coe BP,
|
||
Gillentine MA,
|
||
Wilfert AB,
|
||
Perez-Jurado LA,
|
||
Kvarnung M,
|
||
Sleyp Y,
|
||
Earl RK,
|
||
Rosenfeld JA,
|
||
Geisheker MR,
|
||
Han L,
|
||
Du B,
|
||
Barnett C,
|
||
Thompson E,
|
||
Shaw M,
|
||
Carroll R,
|
||
Friend K,
|
||
Catford R,
|
||
Palmer EE,
|
||
Zou X,
|
||
Ou J,
|
||
Li H,
|
||
Guo H,
|
||
Gerdts J,
|
||
Avola E,
|
||
Calabrese G,
|
||
Elia M,
|
||
Greco D,
|
||
Lindstrand A,
|
||
Nordgren A,
|
||
Anderlid BM,
|
||
Vandeweyer G,
|
||
Van Dijck A,
|
||
Van der Aa N,
|
||
McKenna B,
|
||
Hancarova M,
|
||
Bendova S,
|
||
Havlovicova M,
|
||
Malerba G,
|
||
Bernardina BD,
|
||
Muglia P,
|
||
van Haeringen A,
|
||
Hoffer MJV,
|
||
Franke B,
|
||
Cappuccio G,
|
||
Delatycki M,
|
||
Lockhart PJ,
|
||
Manning MA,
|
||
Liu P,
|
||
Scheffer IE,
|
||
Brunetti-Pierri N,
|
||
Rommelse N,
|
||
Amaral DG,
|
||
Santen GWE,
|
||
Trabetti E,
|
||
Sedláček Z,
|
||
Michaelson JJ,
|
||
Pierce K,
|
||
Courchesne E,
|
||
Kooy RF;
|
||
SPARK Consortium,
|
||
Nordenskjöld M,
|
||
Romano C,
|
||
Peeters H,
|
||
Bernier RA,
|
||
Gecz J,
|
||
Xia K,
|
||
Eichler EE</span><br />
|
||
<span class="medgenPMjournal">Nat Commun</span>
|
||
2020 Oct 1;11(1):4932.
|
||
doi: 10.1038/s41467-020-18723-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33004838" target="_blank">33004838</a><a href="/pmc/articles/PMC7530681" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32374377">Etiology of Autism Spectrum Disorders and Autistic Traits Over Time.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Taylor MJ,
|
||
Rosenqvist MA,
|
||
Larsson H,
|
||
Gillberg C,
|
||
D'Onofrio BM,
|
||
Lichtenstein P,
|
||
Lundström S</span><br />
|
||
<span class="medgenPMjournal">JAMA Psychiatry</span>
|
||
2020 Sep 1;77(9):936-943.
|
||
doi: 10.1001/jamapsychiatry.2020.0680.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32374377" target="_blank">32374377</a><a href="/pmc/articles/PMC7203675" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31314057">Association of Genetic and Environmental Factors With Autism in a 5-Country Cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bai D,
|
||
Yip BHK,
|
||
Windham GC,
|
||
Sourander A,
|
||
Francis R,
|
||
Yoffe R,
|
||
Glasson E,
|
||
Mahjani B,
|
||
Suominen A,
|
||
Leonard H,
|
||
Gissler M,
|
||
Buxbaum JD,
|
||
Wong K,
|
||
Schendel D,
|
||
Kodesh A,
|
||
Breshnahan M,
|
||
Levine SZ,
|
||
Parner ET,
|
||
Hansen SN,
|
||
Hultman C,
|
||
Reichenberg A,
|
||
Sandin S</span><br />
|
||
<span class="medgenPMjournal">JAMA Psychiatry</span>
|
||
2019 Oct 1;76(10):1035-1043.
|
||
doi: 10.1001/jamapsychiatry.2019.1411.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31314057" target="_blank">31314057</a><a href="/pmc/articles/PMC6646998" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30851399">Recurrence Risk of Autism in Siblings and Cousins: A Multinational, Population-Based Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hansen SN,
|
||
Schendel DE,
|
||
Francis RW,
|
||
Windham GC,
|
||
Bresnahan M,
|
||
Levine SZ,
|
||
Reichenberg A,
|
||
Gissler M,
|
||
Kodesh A,
|
||
Bai D,
|
||
Yip BHK,
|
||
Leonard H,
|
||
Sandin S,
|
||
Buxbaum JD,
|
||
Hultman C,
|
||
Sourander A,
|
||
Glasson EJ,
|
||
Wong K,
|
||
Öberg R,
|
||
Parner ET</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Child Adolesc Psychiatry</span>
|
||
2019 Sep;58(9):866-875.
|
||
Epub 2019 Mar 6
|
||
doi: 10.1016/j.jaac.2018.11.017.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30851399" target="_blank">30851399</a><a href="/pmc/articles/PMC6708733" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24794370">The familial risk of autism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sandin S,
|
||
Lichtenstein P,
|
||
Kuja-Halkola R,
|
||
Larsson H,
|
||
Hultman CM,
|
||
Reichenberg A</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2014 May 7;311(17):1770-7.
|
||
doi: 10.1001/jama.2014.4144.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24794370" target="_blank">24794370</a><a href="/pmc/articles/PMC4381277" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%2017%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (131)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32374377">Etiology of Autism Spectrum Disorders and Autistic Traits Over Time.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Taylor MJ,
|
||
Rosenqvist MA,
|
||
Larsson H,
|
||
Gillberg C,
|
||
D'Onofrio BM,
|
||
Lichtenstein P,
|
||
Lundström S</span><br />
|
||
<span class="medgenPMjournal">JAMA Psychiatry</span>
|
||
2020 Sep 1;77(9):936-943.
|
||
doi: 10.1001/jamapsychiatry.2020.0680.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32374377" target="_blank">32374377</a><a href="/pmc/articles/PMC7203675" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31314057">Association of Genetic and Environmental Factors With Autism in a 5-Country Cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bai D,
|
||
Yip BHK,
|
||
Windham GC,
|
||
Sourander A,
|
||
Francis R,
|
||
Yoffe R,
|
||
Glasson E,
|
||
Mahjani B,
|
||
Suominen A,
|
||
Leonard H,
|
||
Gissler M,
|
||
Buxbaum JD,
|
||
Wong K,
|
||
Schendel D,
|
||
Kodesh A,
|
||
Breshnahan M,
|
||
Levine SZ,
|
||
Parner ET,
|
||
Hansen SN,
|
||
Hultman C,
|
||
Reichenberg A,
|
||
Sandin S</span><br />
|
||
<span class="medgenPMjournal">JAMA Psychiatry</span>
|
||
2019 Oct 1;76(10):1035-1043.
|
||
doi: 10.1001/jamapsychiatry.2019.1411.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31314057" target="_blank">31314057</a><a href="/pmc/articles/PMC6646998" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30851399">Recurrence Risk of Autism in Siblings and Cousins: A Multinational, Population-Based Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hansen SN,
|
||
Schendel DE,
|
||
Francis RW,
|
||
Windham GC,
|
||
Bresnahan M,
|
||
Levine SZ,
|
||
Reichenberg A,
|
||
Gissler M,
|
||
Kodesh A,
|
||
Bai D,
|
||
Yip BHK,
|
||
Leonard H,
|
||
Sandin S,
|
||
Buxbaum JD,
|
||
Hultman C,
|
||
Sourander A,
|
||
Glasson EJ,
|
||
Wong K,
|
||
Öberg R,
|
||
Parner ET</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Child Adolesc Psychiatry</span>
|
||
2019 Sep;58(9):866-875.
|
||
Epub 2019 Mar 6
|
||
doi: 10.1016/j.jaac.2018.11.017.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30851399" target="_blank">30851399</a><a href="/pmc/articles/PMC6708733" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29413113">Aluminium in brain tissue in autism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mold M,
|
||
Umar D,
|
||
King A,
|
||
Exley C</span><br />
|
||
<span class="medgenPMjournal">J Trace Elem Med Biol</span>
|
||
2018 Mar;46:76-82.
|
||
Epub 2017 Nov 26
|
||
doi: 10.1016/j.jtemb.2017.11.012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29413113" target="_blank">29413113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24794370">The familial risk of autism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sandin S,
|
||
Lichtenstein P,
|
||
Kuja-Halkola R,
|
||
Larsson H,
|
||
Hultman CM,
|
||
Reichenberg A</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2014 May 7;311(17):1770-7.
|
||
doi: 10.1001/jama.2014.4144.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24794370" target="_blank">24794370</a><a href="/pmc/articles/PMC4381277" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%2017%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (78)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38811692">Polygenic risk of social isolation behavior and its influence on psychopathology and personality.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Socrates AJ,
|
||
Mullins N,
|
||
Gur RC,
|
||
Gur RE,
|
||
Stahl E,
|
||
O'Reilly PF,
|
||
Reichenberg A,
|
||
Jones H,
|
||
Zammit S,
|
||
Velthorst E</span><br />
|
||
<span class="medgenPMjournal">Mol Psychiatry</span>
|
||
2024 Nov;29(11):3599-3606.
|
||
Epub 2024 May 30
|
||
doi: 10.1038/s41380-024-02617-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38811692" target="_blank">38811692</a><a href="/pmc/articles/PMC11541194" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38070418">Prenatal caffeine exposure induces autism-like behaviors in offspring under a high-fat diet via the gut microbiota-IL-17A-brain axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang T,
|
||
Zhang S,
|
||
Luo M,
|
||
Lu M,
|
||
Wei L,
|
||
Zhou X,
|
||
Wang H,
|
||
Xu D</span><br />
|
||
<span class="medgenPMjournal">Ecotoxicol Environ Saf</span>
|
||
2024 Jan 1;269:115797.
|
||
Epub 2023 Dec 8
|
||
doi: 10.1016/j.ecoenv.2023.115797.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38070418" target="_blank">38070418</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33717063">Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cristofori F,
|
||
Dargenio VN,
|
||
Dargenio C,
|
||
Miniello VL,
|
||
Barone M,
|
||
Francavilla R</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2021;12:578386.
|
||
Epub 2021 Feb 26
|
||
doi: 10.3389/fimmu.2021.578386.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33717063" target="_blank">33717063</a><a href="/pmc/articles/PMC7953067" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27351598">Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Theoharides TC,
|
||
Tsilioni I,
|
||
Patel AB,
|
||
Doyle R</span><br />
|
||
<span class="medgenPMjournal">Transl Psychiatry</span>
|
||
2016 Jun 28;6(6):e844.
|
||
doi: 10.1038/tp.2016.77.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27351598" target="_blank">27351598</a><a href="/pmc/articles/PMC4931610" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20166940">Primate-accelerated evolutionary genes: novel routes to drug discovery in psychiatric disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moalic JM,
|
||
Le Strat Y,
|
||
Lepagnol-Bestel AM,
|
||
Ramoz N,
|
||
Loe-Mie Y,
|
||
Maussion G,
|
||
Gorwood P,
|
||
Simonneau M</span><br />
|
||
<span class="medgenPMjournal">Curr Med Chem</span>
|
||
2010;17(13):1300-16.
|
||
doi: 10.2174/092986710790936338.
|
||
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van Binsbergen E,
|
||
Bulk S,
|
||
van Rossem E,
|
||
Vanakker O,
|
||
Armstrong R,
|
||
Park SM,
|
||
Greenhalgh L,
|
||
Maye U,
|
||
Neill NJ,
|
||
Abbott KM,
|
||
Sell S,
|
||
Ladda R,
|
||
Farber DM,
|
||
Bader PI,
|
||
Cushing T,
|
||
Drautz JM,
|
||
Konczal L,
|
||
Nash P,
|
||
de Los Reyes E,
|
||
Carter MT,
|
||
Hopkins E,
|
||
Marshall CR,
|
||
Osborne LR,
|
||
Gripp KW,
|
||
Thrush DL,
|
||
Hashimoto S,
|
||
Gastier-Foster JM,
|
||
Astbury C,
|
||
Ylstra B,
|
||
Meijers-Heijboer H,
|
||
Posthuma D,
|
||
Menten B,
|
||
Mortier G,
|
||
Scherer SW,
|
||
Eichler EE,
|
||
Girirajan S,
|
||
Katsanis N,
|
||
Groffen AJ,
|
||
Sistermans EA</span><br />
|
||
<span class="medgenPMjournal">Am J Hum Genet</span>
|
||
2013 Feb 7;92(2):210-20.
|
||
Epub 2013 Jan 17
|
||
doi: 10.1016/j.ajhg.2012.12.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23332918" target="_blank">23332918</a><a href="/pmc/articles/PMC3567268" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%2017%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (107)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/33143244">Association of Allelic Variants of the Reelin Gene with Autistic Spectrum Disorder: A Systematic Review and Meta-Analysis of Candidate Gene Association Studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hernández-García I,
|
||
Chamorro AJ,
|
||
Ternavasio-de la Vega HG,
|
||
Carbonell C,
|
||
Marcos M,
|
||
Mirón-Canelo JA</span><br />
|
||
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
|
||
2020 Oct 30;17(21)
|
||
doi: 10.3390/ijerph17218010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33143244" target="_blank">33143244</a><a href="/pmc/articles/PMC7663127" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20345955">The neurology of coeliac disease in childhood: what is the evidence? A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lionetti E,
|
||
Francavilla R,
|
||
Pavone P,
|
||
Pavone L,
|
||
Francavilla T,
|
||
Pulvirenti A,
|
||
Giugno R,
|
||
Ruggieri M</span><br />
|
||
<span class="medgenPMjournal">Dev Med Child Neurol</span>
|
||
2010 Aug;52(8):700-7.
|
||
Epub 2010 Mar 19
|
||
doi: 10.1111/j.1469-8749.2010.03647.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20345955" target="_blank">20345955</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%2017%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
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</div>
|
||
|
||
<div class="portlet mgSection" id="ID_106">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C3150693%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (9)</a></li>
|
||
<li><a href="/gtr/tests?term=C3150693%5bDISCUI%5d&filter=method%3A2%5F29" target="_blank">Detection of homozygosity (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C3150693%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (13)</a></li>
|
||
<li><a href="/gtr/tests?term=C3150693%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (2)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C3150693%5bDISCUI%5d" target="_blank">See all (15)</a></total></li>
|
||
</ul></div>
|
||
</div>
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||
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||
<div class="portlet mgSection" id="ID_119">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=613436" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Autism,%20susceptibility%20to,%2017" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(autism%2C%20susceptibility%20to%2C%2017)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_115">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=603290" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=22941[geneid]" target="_blank">View SHANK2 variations in ClinVar</a></li><li><a href="https://catalog.coriell.org/Search?q=613436" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_116">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/autism_17" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Autism,%20susceptibility%20to,%2017" target="_blank">MedlinePlus</a></li></ul></div>
|
||
</div>
|
||
</div>
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Reviews</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pubmed/clinical?term=Autism,%20susceptibility%20to,%2017" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed?term=Autism,%20susceptibility%20to,%2017%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<!-- MedGen supplemental column ends here -->
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=462043" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=medgen_gene_diseases&from_uid=462043" ref="log$=recordlinks">Gene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in NCBI Gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C3150693[DISCUI]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C3150693[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&from_uid=462043" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim_gene&from_uid=462043" ref="log$=recordlinks">OMIM(Genes)</a>
|
||
<div class="brieflinkpop offscreen_noflow">OMIM records containing genes associated with phenotypes registered in MedGen</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=462043" ref="log$=recordlinks">PMC Articles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=462043" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed_omim&from_uid=462043" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67cc2cc9f4a390645e4f1331">Autism, susceptibility to, 17</a>
|
||
<div class="ralinkpop offscreen_noflow">Autism, susceptibility to, 17<div class="brieflinkpopdesc"></div></div>
|
||
<div class="tertiary">MedGen</div>
|
||
</li>
|
||
<li class="ra_qry two_line">
|
||
<a class="htb" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67cc2cc8a68b6b5afc8457de">C3150693[conceptid] <span class="number">(1)</span></a>
|
||
<div class="tertiary">MedGen</div>
|
||
</li>
|
||
<li class="ra_qry ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67cc2cc784f3725e594bef46">C3150677[trait identifier] AND "Fulgent Genetics, Fulgent Genetic... <span class="number">(1)</span></a>
|
||
<div class="ralinkpop offscreen_noflow">C3150677[trait identifier] AND "Fulgent Genetics, Fulgent Genetics"[submitter]<div class="brieflinkpopdesc">Search</div></div>
|
||
<div class="tertiary">ClinVar</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67cc2cc684f3725e594be9bd">Autism, susceptibility to, 16</a>
|
||
<div class="ralinkpop offscreen_noflow">Autism, susceptibility to, 16<div class="brieflinkpopdesc"></div></div>
|
||
<div class="tertiary">MedGen</div>
|
||
</li>
|
||
<li class="ra_qry two_line">
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