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<meta name="keywords" content="C3149463, finding, hdlcq10, high density lipoprotein cholesterol level quantitative trait locus 10, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="" /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=460813
|
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ConceptID=C3149463
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">High density lipoprotein cholesterol level quantitative trait locus 10</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>460813</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C3149463</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>HDLCQ10; HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 10</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/118470" target="_blank">118470</a>; <a href="https://omim.org/entry/143470" target="_blank">143470</a></td></tr>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/22116284">A two-step genetic study on quantitative precursors of coronary artery disease in a homogeneous Indian population: case-control association discovery and validation by transmission-disequilibrium test.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mallik S,
|
||
Majumder PP</span><br />
|
||
<span class="medgenPMjournal">J Biosci</span>
|
||
2011 Dec;36(5):857-68.
|
||
doi: 10.1007/s12038-011-9148-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22116284" target="_blank">22116284</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(high%20density%20lipoprotein%20cholesterol%20level%20quantitative%20trait%20locus%2010)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1)</a></div></div>
|
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</div>
|
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<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39201500">Investigating Genetic Overlap between Alzheimer's Disease, Lipids, and Coronary Artery Disease: A Large-Scale Genome-Wide Cross Trait Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kirby A,
|
||
Porter T,
|
||
Adewuyi EO,
|
||
Laws SM</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2024 Aug 13;25(16)
|
||
doi: 10.3390/ijms25168814.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39201500" target="_blank">39201500</a><a href="/pmc/articles/PMC11354907" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38363475">Association of statin use with osteoporosis risk: a drug-targeted Mendelian randomization study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ren Z,
|
||
Zhou L</span><br />
|
||
<span class="medgenPMjournal">Inflammopharmacology</span>
|
||
2024 Apr;32(2):1253-1261.
|
||
Epub 2024 Feb 16
|
||
doi: 10.1007/s10787-024-01441-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38363475" target="_blank">38363475</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37929782">Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu C,
|
||
Bakshi A,
|
||
Watts GF,
|
||
Renton AE,
|
||
Fulton-Howard B,
|
||
Goate AM,
|
||
Natarajan P,
|
||
Chasman DI,
|
||
Robman L,
|
||
Woods RL,
|
||
Guymer R,
|
||
Wolfe R,
|
||
Thao LTP,
|
||
McNeil JJ,
|
||
Tonkin AM,
|
||
Nicholls SJ,
|
||
Lacaze P</span><br />
|
||
<span class="medgenPMjournal">J Am Heart Assoc</span>
|
||
2023 Nov 7;12(21):e031459.
|
||
Epub 2023 Nov 6
|
||
doi: 10.1161/JAHA.123.031459.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37929782" target="_blank">37929782</a><a href="/pmc/articles/PMC10727421" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34866576">Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang W,
|
||
Xiao J,
|
||
Ji J,
|
||
Chen L</span><br />
|
||
<span class="medgenPMjournal">Elife</span>
|
||
2021 Dec 6;10
|
||
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<span class="bold">PMID: </span><a href="/pubmed/34866576" target="_blank">34866576</a><a href="/pmc/articles/PMC8709572" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25493549">Association between Expression Quantitative Trait Loci and Metabolic Traits in Two Korean Populations.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hong KW,
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<span class="bold">PMID: </span><a href="/pubmed/25493549" target="_blank">25493549</a><a href="/pmc/articles/PMC4262412" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22High%20density%20lipoprotein%20cholesterol%20level%20quantitative%20trait%20locus%2010%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (36)</a></div><h3 class="subhead">Diagnosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/27183119">Advances in Exercise, Fitness, and Performance Genomics in 2015.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kirby A,
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<span class="bold">PMID: </span><a href="/pubmed/39201500" target="_blank">39201500</a><a href="/pmc/articles/PMC11354907" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/38363475">Association of statin use with osteoporosis risk: a drug-targeted Mendelian randomization study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ren Z,
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<div class="portlet_content ln"><span class="medgenPMauthor">de Klerk JA,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22High%20density%20lipoprotein%20cholesterol%20level%20quantitative%20trait%20locus%2010%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (11)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38363475">Association of statin use with osteoporosis risk: a drug-targeted Mendelian randomization study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ren Z,
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Zhou L</span><br />
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2024 Apr;32(2):1253-1261.
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Epub 2024 Feb 16
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doi: 10.1007/s10787-024-01441-y.
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<span class="bold">PMID: </span><a href="/pubmed/38363475" target="_blank">38363475</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/27183119">Advances in Exercise, Fitness, and Performance Genomics in 2015.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sarzynski MA,
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Loos RJ,
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Lucia A,
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Pérusse L,
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Wolfarth B,
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<div class="portlet_content ln"><span class="medgenPMauthor">Kirby A,
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<span class="bold">PMID: </span><a href="/pubmed/39201500" target="_blank">39201500</a><a href="/pmc/articles/PMC11354907" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/38363475">Association of statin use with osteoporosis risk: a drug-targeted Mendelian randomization study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ren Z,
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Zhou L</span><br />
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<span class="medgenPMjournal">Inflammopharmacology</span>
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Epub 2024 Feb 16
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doi: 10.1007/s10787-024-01441-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38363475" target="_blank">38363475</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37929782">Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu C,
|
||
Bakshi A,
|
||
Watts GF,
|
||
Renton AE,
|
||
Fulton-Howard B,
|
||
Goate AM,
|
||
Natarajan P,
|
||
Chasman DI,
|
||
Robman L,
|
||
Woods RL,
|
||
Guymer R,
|
||
Wolfe R,
|
||
Thao LTP,
|
||
McNeil JJ,
|
||
Tonkin AM,
|
||
Nicholls SJ,
|
||
Lacaze P</span><br />
|
||
<span class="medgenPMjournal">J Am Heart Assoc</span>
|
||
2023 Nov 7;12(21):e031459.
|
||
Epub 2023 Nov 6
|
||
doi: 10.1161/JAHA.123.031459.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37929782" target="_blank">37929782</a><a href="/pmc/articles/PMC10727421" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34866576">Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang W,
|
||
Xiao J,
|
||
Ji J,
|
||
Chen L</span><br />
|
||
<span class="medgenPMjournal">Elife</span>
|
||
2021 Dec 6;10
|
||
doi: 10.7554/eLife.73873.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34866576" target="_blank">34866576</a><a href="/pmc/articles/PMC8709572" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div class="nl"><a target="_blank" href="/pubmed/27183119">Advances in Exercise, Fitness, and Performance Genomics in 2015.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Sarzynski MA,
|
||
Loos RJ,
|
||
Lucia A,
|
||
Pérusse L,
|
||
Roth SM,
|
||
Wolfarth B,
|
||
Rankinen T,
|
||
Bouchard C</span><br />
|
||
<span class="medgenPMjournal">Med Sci Sports Exerc</span>
|
||
2016 Oct;48(10):1906-16.
|
||
doi: 10.1249/MSS.0000000000000982.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27183119" target="_blank">27183119</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22High%20density%20lipoprotein%20cholesterol%20level%20quantitative%20trait%20locus%2010%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (24)</a></div></div>
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