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<meta name="keywords" content="C2931122, disease or syndrome, dsg1, keratoderma, palmoplantar striate form 1, keratoderma, palmoplantar, striate form 1, keratoderma, palmoplantar, striate form i, keratosis palmoplantaris striata 1, keratosis palmoplantaris striata i, keratosis palmoplantaris striata i, ad, kpps1, palmoplantar keratoderma i, focal, palmoplantar keratoderma i, striate, palmoplantar keratoderma i, striate or diffuse, palmoplantar keratoderma i, striate, focal, or diffuse, ppks1, sppk1, striate palmoplantar keratoderma 1, striate palmoplantar keratoderma i, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Striate palmoplantar keratoderma belongs to a group of skin diseases in which there is thickening of the skin on the palms and soles. The striate form is characterized by longitudinal hyperkeratotic lesions extending the length of each finger to the palm, and hyperkeratotic lesions are restricted to regions of the body where pressure and abrasion are greatest (summary by Hunt et al., 2001). Patients with diffuse or focal forms of keratoderma associated with mutation in the DSG1 gene have also been reported (Keren et al., 2005; Milingou et al., 2006). Genetic Heterogeneity of Keratosis Palmoplantaris Striata Type II PPKS (PPKS2; 612908) is caused by mutation in the DSP gene (125647) on chromosome 6. Type III PPKS (PPKS3; 607654) is caused by mutation in the keratin-1 gene (KRT1; 139350) on chromosome 12q. For a general phenotypic description and a discussion of genetic heterogeneity of palmoplantar keratoderma (PPK), see epidermolytic PPK (144200). Nitoiu et al. (2014) reviewed desmosome biology in cardiocutaneous syndromes and inherited skin disease, including discussion of the involvement of the DSG1 and DSP genes." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=419717
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ConceptID=C2931122
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Palmoplantar keratoderma i, striate, focal, or diffuse<span class="h1sub">(SPPK1; PPKS1; KPPS1)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>419717</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C2931122</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Keratoderma, palmoplantar striate form 1; KERATODERMA, PALMOPLANTAR, STRIATE FORM I; KERATOSIS PALMOPLANTARIS STRIATA I; Keratosis Palmoplantaris Striata I, AD; PALMOPLANTAR KERATODERMA I, FOCAL; PALMOPLANTAR KERATODERMA I, STRIATE OR DIFFUSE; Striate palmoplantar keratoderma 1; STRIATE PALMOPLANTAR KERATODERMA I</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="DSG1 - ID: 1828 - NCBI Gene" href="/gene/1828" class="medgenPMinfo">DSG1</a> (18q12.1)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0007859" target="_blank">MONDO:0007859</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/148700" target="_blank">148700</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Striate palmoplantar keratoderma belongs to a group of skin diseases in which there is thickening of the skin on the palms and soles. The striate form is characterized by longitudinal hyperkeratotic lesions extending the length of each finger to the palm, and hyperkeratotic lesions are restricted to regions of the body where pressure and abrasion are greatest (summary by Hunt et al., 2001). Patients with diffuse or focal forms of keratoderma associated with mutation in the DSG1 gene have also been reported (Keren et al., 2005; Milingou et al., 2006). Genetic Heterogeneity of Keratosis Palmoplantaris Striata Type II PPKS (PPKS2; 612908) is caused by mutation in the DSP gene (125647) on chromosome 6. Type III PPKS (PPKS3; 607654) is caused by mutation in the keratin-1 gene (KRT1; 139350) on chromosome 12q. For a general phenotypic description and a discussion of genetic heterogeneity of palmoplantar keratoderma (PPK), see epidermolytic PPK (144200). Nitoiu et al. (2014) reviewed desmosome biology in cardiocutaneous syndromes and inherited skin disease, including discussion of the involvement of the DSG1 and DSP genes. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_44017"><div><strong>Palmoplantar keratosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>44017</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0022596</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Abnormal thickening of the skin localized to the palm of the hand and the sole of the foot.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/44017">Feature record</a> | <a href="/medgen?term=%22Palmoplantar%20keratosis%22%5BClinical%20Features%5D%20OR%2044017%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1635750"><div><strong>Palmoplantar keratoderma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1635750</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551675</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Abnormal thickening of the skin of the palms of the hands and the soles of the feet.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1635750">Feature record</a> | <a href="/medgen?term=%22Palmoplantar%20keratoderma%22%5BClinical%20Features%5D%20OR%201635750%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_5690"><div><strong>Hyperhidrosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5690</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0020458</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Abnormal excessive perspiration (sweating) despite the lack of appropriate stimuli like hot and humid weather.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5690">Feature record</a> | <a href="/medgen?term=%22Hyperhidrosis%22%5BClinical%20Features%5D%20OR%205690%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_39324"><div><strong>Onycholysis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>39324</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0085661</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Detachment of the nail from the nail bed.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/39324">Feature record</a> | <a href="/medgen?term=%22Onycholysis%22%5BClinical%20Features%5D%20OR%2039324%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_66368"><div><strong>Nail dystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66368</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0221260</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Onychodystrophy (nail dystrophy) refers to nail changes apart from changes of the color (nail dyschromia) and involves partial or complete disruption of the various keratinous layers of the nail plate.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/66368">Feature record</a> | <a href="/medgen?term=%22Nail%20dystrophy%22%5BClinical%20Features%5D%20OR%2066368%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_65136"><div><strong>Epidermal acanthosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>65136</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0221270</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Diffuse hypertrophy or thickening of the stratum spinosum of the epidermis (prickle cell layer of the skin).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/65136">Feature record</a> | <a href="/medgen?term=%22Epidermal%20acanthosis%22%5BClinical%20Features%5D%20OR%2065136%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_369197"><div><strong>Yellow nails</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>369197</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1768507</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Sign or Symptom</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Yellowish discoloration of the nails.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/369197">Feature record</a> | <a href="/medgen?term=%22Yellow%20nails%22%5BClinical%20Features%5D%20OR%20369197%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_481177"><div><strong>Hypergranulosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>481177</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3279547</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypergranulosis is an increased thickness of the stratum granulosum.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/481177">Feature record</a> | <a href="/medgen?term=%22Hypergranulosis%22%5BClinical%20Features%5D%20OR%20481177%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_811321"><div><strong>Orthokeratotic hyperkeratosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>811321</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3670629</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A form of hyperkeratosis characterized by thickening of the cornified layer without retained nuclei.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/811321">Feature record</a> | <a href="/medgen?term=%22Orthokeratotic%20hyperkeratosis%22%5BClinical%20Features%5D%20OR%20811321%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_870416"><div><strong>Streaks of hyperkeratosis along each finger onto the palm</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>870416</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4024861</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/870416">Feature record</a> | <a href="/medgen?term=%22Streaks%20of%20hyperkeratosis%20along%20each%20finger%20onto%20the%20palm%22%5BClinical%20Features%5D%20OR%20870416%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_870430"><div><strong>Palmoplantar blistering</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>870430</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4024876</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A type of blistering that affects the skin of the palms of the hands and the soles of the feet.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/870430">Feature record</a> | <a href="/medgen?term=%22Palmoplantar%20blistering%22%5BClinical%20Features%5D%20OR%20870430%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of limbs</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1635750" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Palmoplantar keratoderma</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_44017" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Palmoplantar keratosis</a></span></li></ul></li><li><span class="TLline">Abnormality of the integument</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_65136" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Epidermal acanthosis</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_481177" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypergranulosis</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_5690" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyperhidrosis</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_66368" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nail dystrophy</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_39324" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Onycholysis</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_811321" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Orthokeratotic hyperkeratosis</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_870430" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Palmoplantar blistering</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_870416" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Streaks of hyperkeratosis along each finger onto the palm</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_369197" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Yellow nails</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38169088">European expert consensus statement on the systemic treatment of alopecia areata.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rudnicka L,
|
||
Arenbergerova M,
|
||
Grimalt R,
|
||
Ioannides D,
|
||
Katoulis AC,
|
||
Lazaridou E,
|
||
Olszewska M,
|
||
Ovcharenko YS,
|
||
Piraccini BM,
|
||
Prohic A,
|
||
Rakowska A,
|
||
Reygagne P,
|
||
Richard MA,
|
||
Soares RO,
|
||
Starace M,
|
||
Vañó-Galvan S,
|
||
Waskiel-Burnat A</span><br />
|
||
<span class="medgenPMjournal">J Eur Acad Dermatol Venereol</span>
|
||
2024 Apr;38(4):687-694.
|
||
Epub 2024 Jan 2
|
||
doi: 10.1111/jdv.19768.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38169088" target="_blank">38169088</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26314773">Diffuse large B-cell lymphoma (DLBCL): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tilly H,
|
||
Gomes da Silva M,
|
||
Vitolo U,
|
||
Jack A,
|
||
Meignan M,
|
||
Lopez-Guillermo A,
|
||
Walewski J,
|
||
André M,
|
||
Johnson PW,
|
||
Pfreundschuh M,
|
||
Ladetto M;
|
||
ESMO Guidelines Committee</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2015 Sep;26 Suppl 5:v116-25.
|
||
doi: 10.1093/annonc/mdv304.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26314773" target="_blank">26314773</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24491310">Clinical practice guideline: acute otitis externa.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rosenfeld RM,
|
||
Schwartz SR,
|
||
Cannon CR,
|
||
Roland PS,
|
||
Simon GR,
|
||
Kumar KA,
|
||
Huang WW,
|
||
Haskell HW,
|
||
Robertson PJ</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Head Neck Surg</span>
|
||
2014 Feb;150(1 Suppl):S1-S24.
|
||
doi: 10.1177/0194599813517083.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24491310" target="_blank">24491310</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(palmoplantar%20keratoderma%20i%2C%20striate%2C%20focal%2C%20or%20diffuse)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (8578)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34227809">NMR for Mixture Analysis: Concentration-Ordered Spectroscopy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yuan B,
|
||
Zhou Z,
|
||
Jiang B,
|
||
Kamal GM,
|
||
Zhang X,
|
||
Li C,
|
||
Zhou X,
|
||
Liu M</span><br />
|
||
<span class="medgenPMjournal">Anal Chem</span>
|
||
2021 Jul 20;93(28):9697-9703.
|
||
Epub 2021 Jul 6
|
||
doi: 10.1021/acs.analchem.1c00831.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34227809" target="_blank">34227809</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30880356">Monte Carlo simulations in drug release.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kosmidis K,
|
||
Dassios G</span><br />
|
||
<span class="medgenPMjournal">J Pharmacokinet Pharmacodyn</span>
|
||
2019 Apr;46(2):165-172.
|
||
Epub 2019 Mar 18
|
||
doi: 10.1007/s10928-019-09625-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30880356" target="_blank">30880356</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29705031">(3)He diffusion MRI in human lungs.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Woods JC,
|
||
Conradi MS</span><br />
|
||
<span class="medgenPMjournal">J Magn Reson</span>
|
||
2018 Jul;292:90-98.
|
||
Epub 2018 Apr 26
|
||
doi: 10.1016/j.jmr.2018.04.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29705031" target="_blank">29705031</a><a href="/pmc/articles/PMC6386180" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15174633">The flux of oxygen within tissues.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McCabe MG,
|
||
Maguire DJ,
|
||
Bourgain R</span><br />
|
||
<span class="medgenPMjournal">Adv Exp Med Biol</span>
|
||
2003;540:291-5.
|
||
doi: 10.1007/978-1-4757-6125-2_41.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15174633" target="_blank">15174633</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10207918">pH homeostasis in acidophiles.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Matin A</span><br />
|
||
<span class="medgenPMjournal">Novartis Found Symp</span>
|
||
1999;221:152-63; discussion 163-6.
|
||
doi: 10.1002/9780470515631.ch10.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10207918" target="_blank">10207918</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Palmoplantar%20keratoderma%20i%2C%20striate%2C%20focal%2C%20or%20diffuse%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (81100)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28297921">Dephasing and diffusion on the alveolar surface.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Buschle LR,
|
||
Kurz FT,
|
||
Kampf T,
|
||
Wagner WL,
|
||
Duerr J,
|
||
Stiller W,
|
||
Konietzke P,
|
||
Wünnemann F,
|
||
Mall MA,
|
||
Wielpütz MO,
|
||
Schlemmer HP,
|
||
Ziener CH</span><br />
|
||
<span class="medgenPMjournal">Phys Rev E</span>
|
||
2017 Feb;95(2-1):022415.
|
||
Epub 2017 Feb 24
|
||
doi: 10.1103/PhysRevE.95.022415.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28297921" target="_blank">28297921</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27089377">Droplet-based Biosensing for Lab-on-a-Chip, Open Microfluidics Platforms.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dak P,
|
||
Ebrahimi A,
|
||
Swaminathan V,
|
||
Duarte-Guevara C,
|
||
Bashir R,
|
||
Alam MA</span><br />
|
||
<span class="medgenPMjournal">Biosensors (Basel)</span>
|
||
2016 Apr 14;6(2):14.
|
||
doi: 10.3390/bios6020014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27089377" target="_blank">27089377</a><a href="/pmc/articles/PMC4931474" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22006906">Methods in diffuse optical imaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arridge SR</span><br />
|
||
<span class="medgenPMjournal">Philos Trans A Math Phys Eng Sci</span>
|
||
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<div class="nl"><a target="_blank" href="/pubmed/37611107">Measuring utility with diffusion models.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Berlinghieri R,
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Krajbich I,
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Maccheroni F,
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<span class="bold">PMID: </span><a href="/pubmed/37611107" target="_blank">37611107</a><a href="/pmc/articles/PMC10446488" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/27981379">Lung morphometry: the link between structure and function.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Weibel ER</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/27981379" target="_blank">27981379</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Butler T,
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<span class="bold">PMID: </span><a href="/pubmed/21867118" target="_blank">21867118</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/8923594">Scleroderma epidemiology.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Mayes MD</span><br />
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Palmoplantar%20keratoderma%20i%2C%20striate%2C%20focal%2C%20or%20diffuse%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (60887)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37611107">Measuring utility with diffusion models.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Berlinghieri R,
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Krajbich I,
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Maccheroni F,
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Marinacci M,
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Pirazzini M</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/37611107" target="_blank">37611107</a><a href="/pmc/articles/PMC10446488" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29755006">Multiparametric Magnetic Resonance Imaging for Bladder Cancer: Development of VI-RADS (Vesical Imaging-Reporting And Data System).</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Panebianco V,
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Kennish S,
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Salomon G,
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Thomas S,
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<div class="nl"><a target="_blank" href="/pubmed/27981379">Lung morphometry: the link between structure and function.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Weibel ER</span><br />
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<span class="medgenPMjournal">Cell Tissue Res</span>
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2017 Mar;367(3):413-426.
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<span class="bold">PMID: </span><a href="/pubmed/27981379" target="_blank">27981379</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/21867118">Fluctuation-driven Turing patterns.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Butler T,
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Goldenfeld N</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/21867118" target="_blank">21867118</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/19330553">Diffusing capacity.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hegewald MJ</span><br />
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<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
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2009 Dec;37(3):159-66.
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Epub 2009 Mar 31
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doi: 10.1007/s12016-009-8125-2.
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<span class="bold">PMID: </span><a href="/pubmed/19330553" target="_blank">19330553</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Palmoplantar%20keratoderma%20i%2C%20striate%2C%20focal%2C%20or%20diffuse%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (72353)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/36915243">Efficacy of Salvage Treatments in Relapsed or Refractory Diffuse Large B-Cell Lymphoma Including Chimeric Antigen Receptor T-Cell Therapy: A Systematic Review and Meta-Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kim J,
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Cho J,
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Yoon SE,
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Kim WS,
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Kim SJ</span><br />
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2023 Jul;55(3):1031-1047.
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Epub 2023 Mar 13
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<span class="bold">PMID: </span><a href="/pubmed/36915243" target="_blank">36915243</a><a href="/pmc/articles/PMC10372592" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33187340">Nandrolone Decanoate: Use, Abuse and Side Effects.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Patanè FG,
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Liberto A,
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Maria Maglitto AN,
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Malandrino P,
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Esposito M,
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Amico F,
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Cocimano G,
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Rosi GL,
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Condorelli D,
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Nunno ND,
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Montana A</span><br />
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<span class="medgenPMjournal">Medicina (Kaunas)</span>
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2020 Nov 11;56(11)
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<span class="bold">PMID: </span><a href="/pubmed/33187340" target="_blank">33187340</a><a href="/pmc/articles/PMC7696474" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32915254">Prediction of poor neurological outcome in comatose survivors of cardiac arrest: a systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sandroni C,
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D'Arrigo S,
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Cacciola S,
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Hoedemaekers CWE,
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Kamps MJA,
|
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Oddo M,
|
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Taccone FS,
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Di Rocco A,
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Meijer FJA,
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Westhall E,
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Antonelli M,
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Soar J,
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Nolan JP,
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Cronberg T</span><br />
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<span class="medgenPMjournal">Intensive Care Med</span>
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2020 Oct;46(10):1803-1851.
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||
Epub 2020 Sep 11
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doi: 10.1007/s00134-020-06198-w.
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<span class="bold">PMID: </span><a href="/pubmed/32915254" target="_blank">32915254</a><a href="/pmc/articles/PMC7527362" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30305051">The effect of body position on pulmonary function: a systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Katz S,
|
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Arish N,
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Rokach A,
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Zaltzman Y,
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Marcus EL</span><br />
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<span class="medgenPMjournal">BMC Pulm Med</span>
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2018 Oct 11;18(1):159.
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||
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<span class="bold">PMID: </span><a href="/pubmed/30305051" target="_blank">30305051</a><a href="/pmc/articles/PMC6180369" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26526835">Coenzyme Q10 Supplementation and Exercise in Healthy Humans: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sarmiento A,
|
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Diaz-Castro J,
|
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Pulido-Moran M,
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Kajarabille N,
|
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Guisado R,
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<span class="medgenPMjournal">Curr Drug Metab</span>
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<span class="bold">PMID: </span><a href="/pubmed/26526835" target="_blank">26526835</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Palmoplantar%20keratoderma%20i%2C%20striate%2C%20focal%2C%20or%20diffuse%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1903)</a></div></div>
|
||
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|
||
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|
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|
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|
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<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C2931122%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (8)</a></li>
|
||
<li><a href="/gtr/tests?term=C2931122%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (8)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C2931122%5bDISCUI%5d" target="_blank">See all (12)</a></total></li>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=148700" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Palmoplantar%20keratoderma%20i,%20striate,%20focal,%20or%20diffuse" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(palmoplantar%20keratoderma%20i%2C%20striate%2C%20focal%2C%20or%20diffuse)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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