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<!--
UID=382750
ConceptID=C2676021
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Dementia, Lewy body, susceptibility to</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>382750</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C2676021</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>DEMENTIA, LEWY BODY, SUSCEPTIBILITY TO</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>OMIM<span class="superscript">®</span>:</td>
<td><a href="https://omim.org/entry/606463" target="_blank">606463</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/36281704">Challenges in diagnosis and management of delirium in Lewy body disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Richardson S,
Lawson RA,
Price A,
Taylor JP</span><br />
<span class="medgenPMjournal">Acta Psychiatr Scand</span>
2023 May;147(5):475-480.
Epub 2022 Nov 4
doi: 10.1111/acps.13514.
<span class="bold">PMID: </span><a href="/pubmed/36281704" target="_blank">36281704</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32912321">Assessment of genetic risk for improved clinical-neuropathological correlations.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Spencer BE,
Jennings RG,
Fan CC,
Brewer JB</span><br />
<span class="medgenPMjournal">Acta Neuropathol Commun</span>
2020 Sep 10;8(1):160.
doi: 10.1186/s40478-020-01033-1.
<span class="bold">PMID: </span><a href="/pubmed/32912321" target="_blank">32912321</a><a href="/pmc/articles/PMC7488152" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22596266">Apolipoprotein E genotype: the innocent bystander or active bridge between metabolic syndrome and cognitive impairment?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Frisardi V</span><br />
<span class="medgenPMjournal">J Alzheimers Dis</span>
2012;30 Suppl 2:S283-304.
doi: 10.3233/JAD-2012-111568.
<span class="bold">PMID: </span><a href="/pubmed/22596266" target="_blank">22596266</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(dementia%2C%20lewy%20body%2C%20susceptibility%20to)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (7)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/38701790">Genome sequence analyses identify novel risk loci for multiple system atrophy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chia R,
Ray A,
Shah Z,
Ding J,
Ruffo P,
Fujita M,
Menon V,
Saez-Atienzar S,
Reho P,
Kaivola K,
Walton RL,
Reynolds RH,
Karra R,
Sait S,
Akcimen F,
Diez-Fairen M,
Alvarez I,
Fanciulli A,
Stefanova N,
Seppi K,
Duerr S,
Leys F,
Krismer F,
Sidoroff V,
Zimprich A,
Pirker W,
Rascol O,
Foubert-Samier A,
Meissner WG,
Tison F,
Pavy-Le Traon A,
Pellecchia MT,
Barone P,
Russillo MC,
Marín-Lahoz J,
Kulisevsky J,
Torres S,
Mir P,
Periñán MT,
Proukakis C,
Chelban V,
Wu L,
Goh YY,
Parkkinen L,
Hu MT,
Kobylecki C,
Saxon JA,
Rollinson S,
Garland E,
Biaggioni I,
Litvan I,
Rubio I,
Alcalay RN,
Kwei KT,
Lubbe SJ,
Mao Q,
Flanagan ME,
Castellani RJ,
Khurana V,
Ndayisaba A,
Calvo A,
Mora G,
Canosa A,
Floris G,
Bohannan RC,
Moore A,
Norcliffe-Kaufmann L,
Palma JA,
Kaufmann H,
Kim C,
Iba M,
Masliah E,
Dawson TM,
Rosenthal LS,
Pantelyat A,
Albert MS,
Pletnikova O,
Troncoso JC,
Infante J,
Lage C,
Sánchez-Juan P,
Serrano GE,
Beach TG,
Pastor P,
Morris HR,
Albani D,
Clarimon J,
Wenning GK,
Hardy JA,
Ryten M,
Topol E,
Torkamani A,
Chiò A,
Bennett DA,
De Jager PL,
Low PA,
Singer W,
Cheshire WP,
Wszolek ZK,
Dickson DW,
Traynor BJ,
Gibbs JR,
Dalgard CL,
Ross OA,
Houlden H,
Scholz SW</span><br />
<span class="medgenPMjournal">Neuron</span>
2024 Jul 3;112(13):2142-2156.e5.
Epub 2024 May 2
doi: 10.1016/j.neuron.2024.04.002.
<span class="bold">PMID: </span><a href="/pubmed/38701790" target="_blank">38701790</a><a href="/pmc/articles/PMC11223971" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33589841">Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chia R,
Sabir MS,
Bandres-Ciga S,
Saez-Atienzar S,
Reynolds RH,
Gustavsson E,
Walton RL,
Ahmed S,
Viollet C,
Ding J,
Makarious MB,
Diez-Fairen M,
Portley MK,
Shah Z,
Abramzon Y,
Hernandez DG,
Blauwendraat C,
Stone DJ,
Eicher J,
Parkkinen L,
Ansorge O,
Clark L,
Honig LS,
Marder K,
Lemstra A,
St George-Hyslop P,
Londos E,
Morgan K,
Lashley T,
Warner TT,
Jaunmuktane Z,
Galasko D,
Santana I,
Tienari PJ,
Myllykangas L,
Oinas M,
Cairns NJ,
Morris JC,
Halliday GM,
Van Deerlin VM,
Trojanowski JQ,
Grassano M,
Calvo A,
Mora G,
Canosa A,
Floris G,
Bohannan RC,
Brett F,
Gan-Or Z,
Geiger JT,
Moore A,
May P,
Krüger R,
Goldstein DS,
Lopez G,
Tayebi N,
Sidransky E;
American Genome Center,
Norcliffe-Kaufmann L,
Palma JA,
Kaufmann H,
Shakkottai VG,
Perkins M,
Newell KL,
Gasser T,
Schulte C,
Landi F,
Salvi E,
Cusi D,
Masliah E,
Kim RC,
Caraway CA,
Monuki ES,
Brunetti M,
Dawson TM,
Rosenthal LS,
Albert MS,
Pletnikova O,
Troncoso JC,
Flanagan ME,
Mao Q,
Bigio EH,
Rodríguez-Rodríguez E,
Infante J,
Lage C,
González-Aramburu I,
Sanchez-Juan P,
Ghetti B,
Keith J,
Black SE,
Masellis M,
Rogaeva E,
Duyckaerts C,
Brice A,
Lesage S,
Xiromerisiou G,
Barrett MJ,
Tilley BS,
Gentleman S,
Logroscino G,
Serrano GE,
Beach TG,
McKeith IG,
Thomas AJ,
Attems J,
Morris CM,
Palmer L,
Love S,
Troakes C,
Al-Sarraj S,
Hodges AK,
Aarsland D,
Klein G,
Kaiser SM,
Woltjer R,
Pastor P,
Bekris LM,
Leverenz JB,
Besser LM,
Kuzma A,
Renton AE,
Goate A,
Bennett DA,
Scherzer CR,
Morris HR,
Ferrari R,
Albani D,
Pickering-Brown S,
Faber K,
Kukull WA,
Morenas-Rodriguez E,
Lleó A,
Fortea J,
Alcolea D,
Clarimon J,
Nalls MA,
Ferrucci L,
Resnick SM,
Tanaka T,
Foroud TM,
Graff-Radford NR,
Wszolek ZK,
Ferman T,
Boeve BF,
Hardy JA,
Topol EJ,
Torkamani A,
Singleton AB,
Ryten M,
Dickson DW,
Chiò A,
Ross OA,
Gibbs JR,
Dalgard CL,
Traynor BJ,
Scholz SW</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2021 Mar;53(3):294-303.
Epub 2021 Feb 15
doi: 10.1038/s41588-021-00785-3.
<span class="bold">PMID: </span><a href="/pubmed/33589841" target="_blank">33589841</a><a href="/pmc/articles/PMC7946812" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33074286">Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kunkle BW,
Schmidt M,
Klein HU,
Naj AC,
Hamilton-Nelson KL,
Larson EB,
Evans DA,
De Jager PL,
Crane PK,
Buxbaum JD,
Ertekin-Taner N,
Barnes LL,
Fallin MD,
Manly JJ,
Go RCP,
Obisesan TO,
Kamboh MI,
Bennett DA,
Hall KS,
Goate AM,
Foroud TM,
Martin ER,
Wang LS,
Byrd GS,
Farrer LA,
Haines JL,
Schellenberg GD,
Mayeux R,
Pericak-Vance MA,
Reitz C;
Writing Group for the Alzheimers Disease Genetics Consortium (ADGC),
Graff-Radford NR,
Martinez I,
Ayodele T,
Logue MW,
Cantwell LB,
Jean-Francois M,
Kuzma AB,
Adams LD,
Vance JM,
Cuccaro ML,
Chung J,
Mez J,
Lunetta KL,
Jun GR,
Lopez OL,
Hendrie HC,
Reiman EM,
Kowall NW,
Leverenz JB,
Small SA,
Levey AI,
Golde TE,
Saykin AJ,
Starks TD,
Albert MS,
Hyman BT,
Petersen RC,
Sano M,
Wisniewski T,
Vassar R,
Kaye JA,
Henderson VW,
DeCarli C,
LaFerla FM,
Brewer JB,
Miller BL,
Swerdlow RH,
Van Eldik LJ,
Paulson HL,
Trojanowski JQ,
Chui HC,
Rosenberg RN,
Craft S,
Grabowski TJ,
Asthana S,
Morris JC,
Strittmatter SM,
Kukull WA</span><br />
<span class="medgenPMjournal">JAMA Neurol</span>
2021 Jan 1;78(1):102-113.
doi: 10.1001/jamaneurol.2020.3536.
<span class="bold">PMID: </span><a href="/pubmed/33074286" target="_blank">33074286</a><a href="/pmc/articles/PMC7573798" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31755958">Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blauwendraat C,
Reed X,
Krohn L,
Heilbron K,
Bandres-Ciga S,
Tan M,
Gibbs JR,
Hernandez DG,
Kumaran R,
Langston R,
Bonet-Ponce L,
Alcalay RN,
Hassin-Baer S,
Greenbaum L,
Iwaki H,
Leonard HL,
Grenn FP,
Ruskey JA,
Sabir M,
Ahmed S,
Makarious MB,
Pihlstrøm L,
Toft M,
van Hilten JJ,
Marinus J,
Schulte C,
Brockmann K,
Sharma M,
Siitonen A,
Majamaa K,
Eerola-Rautio J,
Tienari PJ;
23andMe Research Team,
Pantelyat A,
Hillis AE,
Dawson TM,
Rosenthal LS,
Albert MS,
Resnick SM,
Ferrucci L,
Morris CM,
Pletnikova O,
Troncoso J,
Grosset D,
Lesage S,
Corvol JC,
Brice A,
Noyce AJ,
Masliah E,
Wood N,
Hardy J,
Shulman LM,
Jankovic J,
Shulman JM,
Heutink P,
Gasser T,
Cannon P,
Scholz SW,
Morris H,
Cookson MR,
Nalls MA,
Gan-Or Z,
Singleton AB</span><br />
<span class="medgenPMjournal">Brain</span>
2020 Jan 1;143(1):234-248.
doi: 10.1093/brain/awz350.
<span class="bold">PMID: </span><a href="/pubmed/31755958" target="_blank">31755958</a><a href="/pmc/articles/PMC6935749" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12480441">The dementias.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ritchie K,
Lovestone S</span><br />
<span class="medgenPMjournal">Lancet</span>
2002 Nov 30;360(9347):1759-66.
doi: 10.1016/S0140-6736(02)11667-9.
<span class="bold">PMID: </span><a href="/pubmed/12480441" target="_blank">12480441</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dementia%2C%20Lewy%20body%2C%20susceptibility%20to%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (158)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/36866576">Overview of late-onset psychoses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Devanand DP,
Jeste DV,
Stroup TS,
Goldberg TE</span><br />
<span class="medgenPMjournal">Int Psychogeriatr</span>
2024 Jan;36(1):28-42.
Epub 2023 Mar 3
doi: 10.1017/S1041610223000157.
<span class="bold">PMID: </span><a href="/pubmed/36866576" target="_blank">36866576</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35678403">The Value of Neuroimaging in Dementia Diagnosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Raji CA,
Benzinger TLS</span><br />
<span class="medgenPMjournal">Continuum (Minneap Minn)</span>
2022 Jun 1;28(3):800-821.
doi: 10.1212/CON.0000000000001133.
<span class="bold">PMID: </span><a href="/pubmed/35678403" target="_blank">35678403</a><a href="/pmc/articles/PMC9993425" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33074286">Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kunkle BW,
Schmidt M,
Klein HU,
Naj AC,
Hamilton-Nelson KL,
Larson EB,
Evans DA,
De Jager PL,
Crane PK,
Buxbaum JD,
Ertekin-Taner N,
Barnes LL,
Fallin MD,
Manly JJ,
Go RCP,
Obisesan TO,
Kamboh MI,
Bennett DA,
Hall KS,
Goate AM,
Foroud TM,
Martin ER,
Wang LS,
Byrd GS,
Farrer LA,
Haines JL,
Schellenberg GD,
Mayeux R,
Pericak-Vance MA,
Reitz C;
Writing Group for the Alzheimers Disease Genetics Consortium (ADGC),
Graff-Radford NR,
Martinez I,
Ayodele T,
Logue MW,
Cantwell LB,
Jean-Francois M,
Kuzma AB,
Adams LD,
Vance JM,
Cuccaro ML,
Chung J,
Mez J,
Lunetta KL,
Jun GR,
Lopez OL,
Hendrie HC,
Reiman EM,
Kowall NW,
Leverenz JB,
Small SA,
Levey AI,
Golde TE,
Saykin AJ,
Starks TD,
Albert MS,
Hyman BT,
Petersen RC,
Sano M,
Wisniewski T,
Vassar R,
Kaye JA,
Henderson VW,
DeCarli C,
LaFerla FM,
Brewer JB,
Miller BL,
Swerdlow RH,
Van Eldik LJ,
Paulson HL,
Trojanowski JQ,
Chui HC,
Rosenberg RN,
Craft S,
Grabowski TJ,
Asthana S,
Morris JC,
Strittmatter SM,
Kukull WA</span><br />
<span class="medgenPMjournal">JAMA Neurol</span>
2021 Jan 1;78(1):102-113.
doi: 10.1001/jamaneurol.2020.3536.
<span class="bold">PMID: </span><a href="/pubmed/33074286" target="_blank">33074286</a><a href="/pmc/articles/PMC7573798" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12498954">Staging of brain pathology related to sporadic Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Braak H,
Del Tredici K,
Rüb U,
de Vos RA,
Jansen Steur EN,
Braak E</span><br />
<span class="medgenPMjournal">Neurobiol Aging</span>
2003 Mar-Apr;24(2):197-211.
doi: 10.1016/s0197-4580(02)00065-9.
<span class="bold">PMID: </span><a href="/pubmed/12498954" target="_blank">12498954</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12480441">The dementias.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ritchie K,
Lovestone S</span><br />
<span class="medgenPMjournal">Lancet</span>
2002 Nov 30;360(9347):1759-66.
doi: 10.1016/S0140-6736(02)11667-9.
<span class="bold">PMID: </span><a href="/pubmed/12480441" target="_blank">12480441</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dementia%2C%20Lewy%20body%2C%20susceptibility%20to%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (92)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/39347895">Identification of Potential Causal Genes for Neurodegenerative Diseases by Mitochondria-Related Genome-Wide Mendelian Randomization.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yin KF,
Chen T,
Gu XJ,
Jiang Z,
Su WM,
Duan QQ,
Wen XJ,
Cao B,
Li JR,
Chi LY,
Chen YP</span><br />
<span class="medgenPMjournal">Mol Neurobiol</span>
2025 Mar;62(3):3892-3902.
Epub 2024 Sep 30
doi: 10.1007/s12035-024-04528-3.
<span class="bold">PMID: </span><a href="/pubmed/39347895" target="_blank">39347895</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36866576">Overview of late-onset psychoses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Devanand DP,
Jeste DV,
Stroup TS,
Goldberg TE</span><br />
<span class="medgenPMjournal">Int Psychogeriatr</span>
2024 Jan;36(1):28-42.
Epub 2023 Mar 3
doi: 10.1017/S1041610223000157.
<span class="bold">PMID: </span><a href="/pubmed/36866576" target="_blank">36866576</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35835752">COVID-19 and risk of neurodegenerative disorders: A Mendelian randomization study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li C,
Liu J,
Lin J,
Shang H</span><br />
<span class="medgenPMjournal">Transl Psychiatry</span>
2022 Jul 14;12(1):283.
doi: 10.1038/s41398-022-02052-3.
<span class="bold">PMID: </span><a href="/pubmed/35835752" target="_blank">35835752</a><a href="/pmc/articles/PMC9281279" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27098668">Olfactory dysfunction is related to postoperative delirium in Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kim MS,
Yoon JH,
Kim HJ,
Yong SW,
Hong JM</span><br />
<span class="medgenPMjournal">J Neural Transm (Vienna)</span>
2016 Jun;123(6):589-94.
Epub 2016 Apr 20
doi: 10.1007/s00702-016-1555-0.
<span class="bold">PMID: </span><a href="/pubmed/27098668" target="_blank">27098668</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12480441">The dementias.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ritchie K,
Lovestone S</span><br />
<span class="medgenPMjournal">Lancet</span>
2002 Nov 30;360(9347):1759-66.
doi: 10.1016/S0140-6736(02)11667-9.
<span class="bold">PMID: </span><a href="/pubmed/12480441" target="_blank">12480441</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dementia%2C%20Lewy%20body%2C%20susceptibility%20to%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/39885558">Lewy body diseases and the gut.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sampson TR,
Tansey MG,
West AB,
Liddle RA</span><br />
<span class="medgenPMjournal">Mol Neurodegener</span>
2025 Jan 30;20(1):14.
doi: 10.1186/s13024-025-00804-5.
<span class="bold">PMID: </span><a href="/pubmed/39885558" target="_blank">39885558</a><a href="/pmc/articles/PMC11783828" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36866576">Overview of late-onset psychoses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Devanand DP,
Jeste DV,
Stroup TS,
Goldberg TE</span><br />
<span class="medgenPMjournal">Int Psychogeriatr</span>
2024 Jan;36(1):28-42.
Epub 2023 Mar 3
doi: 10.1017/S1041610223000157.
<span class="bold">PMID: </span><a href="/pubmed/36866576" target="_blank">36866576</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37169935">The heterogeneity of Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wüllner U,
Borghammer P,
Choe CU,
Csoti I,
Falkenburger B,
Gasser T,
Lingor P,
Riederer P</span><br />
<span class="medgenPMjournal">J Neural Transm (Vienna)</span>
2023 Jun;130(6):827-838.
Epub 2023 May 11
doi: 10.1007/s00702-023-02635-4.
<span class="bold">PMID: </span><a href="/pubmed/37169935" target="_blank">37169935</a><a href="/pmc/articles/PMC10174621" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27098668">Olfactory dysfunction is related to postoperative delirium in Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kim MS,
Yoon JH,
Kim HJ,
Yong SW,
Hong JM</span><br />
<span class="medgenPMjournal">J Neural Transm (Vienna)</span>
2016 Jun;123(6):589-94.
Epub 2016 Apr 20
doi: 10.1007/s00702-016-1555-0.
<span class="bold">PMID: </span><a href="/pubmed/27098668" target="_blank">27098668</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12498954">Staging of brain pathology related to sporadic Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Braak H,
Del Tredici K,
Rüb U,
de Vos RA,
Jansen Steur EN,
Braak E</span><br />
<span class="medgenPMjournal">Neurobiol Aging</span>
2003 Mar-Apr;24(2):197-211.
doi: 10.1016/s0197-4580(02)00065-9.
<span class="bold">PMID: </span><a href="/pubmed/12498954" target="_blank">12498954</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dementia%2C%20Lewy%20body%2C%20susceptibility%20to%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (46)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/38527854">Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Reus LM,
Jansen IE,
Tijms BM,
Visser PJ,
Tesi N,
van der Lee SJ,
Vermunt L,
Peeters CFW,
De Groot LA,
Hok-A-Hin YS,
Chen-Plotkin A,
Irwin DJ,
Hu WT,
Meeter LH,
van Swieten JC,
Holstege H,
Hulsman M,
Lemstra AW,
Pijnenburg YAL,
van der Flier WM,
Teunissen CE,
Del Campo Milan M</span><br />
<span class="medgenPMjournal">Brain</span>
2024 Oct 3;147(10):3522-3533.
doi: 10.1093/brain/awae090.
<span class="bold">PMID: </span><a href="/pubmed/38527854" target="_blank">38527854</a><a href="/pmc/articles/PMC11449142" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33589841">Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chia R,
Sabir MS,
Bandres-Ciga S,
Saez-Atienzar S,
Reynolds RH,
Gustavsson E,
Walton RL,
Ahmed S,
Viollet C,
Ding J,
Makarious MB,
Diez-Fairen M,
Portley MK,
Shah Z,
Abramzon Y,
Hernandez DG,
Blauwendraat C,
Stone DJ,
Eicher J,
Parkkinen L,
Ansorge O,
Clark L,
Honig LS,
Marder K,
Lemstra A,
St George-Hyslop P,
Londos E,
Morgan K,
Lashley T,
Warner TT,
Jaunmuktane Z,
Galasko D,
Santana I,
Tienari PJ,
Myllykangas L,
Oinas M,
Cairns NJ,
Morris JC,
Halliday GM,
Van Deerlin VM,
Trojanowski JQ,
Grassano M,
Calvo A,
Mora G,
Canosa A,
Floris G,
Bohannan RC,
Brett F,
Gan-Or Z,
Geiger JT,
Moore A,
May P,
Krüger R,
Goldstein DS,
Lopez G,
Tayebi N,
Sidransky E;
American Genome Center,
Norcliffe-Kaufmann L,
Palma JA,
Kaufmann H,
Shakkottai VG,
Perkins M,
Newell KL,
Gasser T,
Schulte C,
Landi F,
Salvi E,
Cusi D,
Masliah E,
Kim RC,
Caraway CA,
Monuki ES,
Brunetti M,
Dawson TM,
Rosenthal LS,
Albert MS,
Pletnikova O,
Troncoso JC,
Flanagan ME,
Mao Q,
Bigio EH,
Rodríguez-Rodríguez E,
Infante J,
Lage C,
González-Aramburu I,
Sanchez-Juan P,
Ghetti B,
Keith J,
Black SE,
Masellis M,
Rogaeva E,
Duyckaerts C,
Brice A,
Lesage S,
Xiromerisiou G,
Barrett MJ,
Tilley BS,
Gentleman S,
Logroscino G,
Serrano GE,
Beach TG,
McKeith IG,
Thomas AJ,
Attems J,
Morris CM,
Palmer L,
Love S,
Troakes C,
Al-Sarraj S,
Hodges AK,
Aarsland D,
Klein G,
Kaiser SM,
Woltjer R,
Pastor P,
Bekris LM,
Leverenz JB,
Besser LM,
Kuzma A,
Renton AE,
Goate A,
Bennett DA,
Scherzer CR,
Morris HR,
Ferrari R,
Albani D,
Pickering-Brown S,
Faber K,
Kukull WA,
Morenas-Rodriguez E,
Lleó A,
Fortea J,
Alcolea D,
Clarimon J,
Nalls MA,
Ferrucci L,
Resnick SM,
Tanaka T,
Foroud TM,
Graff-Radford NR,
Wszolek ZK,
Ferman T,
Boeve BF,
Hardy JA,
Topol EJ,
Torkamani A,
Singleton AB,
Ryten M,
Dickson DW,
Chiò A,
Ross OA,
Gibbs JR,
Dalgard CL,
Traynor BJ,
Scholz SW</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2021 Mar;53(3):294-303.
Epub 2021 Feb 15
doi: 10.1038/s41588-021-00785-3.
<span class="bold">PMID: </span><a href="/pubmed/33589841" target="_blank">33589841</a><a href="/pmc/articles/PMC7946812" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33074286">Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kunkle BW,
Schmidt M,
Klein HU,
Naj AC,
Hamilton-Nelson KL,
Larson EB,
Evans DA,
De Jager PL,
Crane PK,
Buxbaum JD,
Ertekin-Taner N,
Barnes LL,
Fallin MD,
Manly JJ,
Go RCP,
Obisesan TO,
Kamboh MI,
Bennett DA,
Hall KS,
Goate AM,
Foroud TM,
Martin ER,
Wang LS,
Byrd GS,
Farrer LA,
Haines JL,
Schellenberg GD,
Mayeux R,
Pericak-Vance MA,
Reitz C;
Writing Group for the Alzheimers Disease Genetics Consortium (ADGC),
Graff-Radford NR,
Martinez I,
Ayodele T,
Logue MW,
Cantwell LB,
Jean-Francois M,
Kuzma AB,
Adams LD,
Vance JM,
Cuccaro ML,
Chung J,
Mez J,
Lunetta KL,
Jun GR,
Lopez OL,
Hendrie HC,
Reiman EM,
Kowall NW,
Leverenz JB,
Small SA,
Levey AI,
Golde TE,
Saykin AJ,
Starks TD,
Albert MS,
Hyman BT,
Petersen RC,
Sano M,
Wisniewski T,
Vassar R,
Kaye JA,
Henderson VW,
DeCarli C,
LaFerla FM,
Brewer JB,
Miller BL,
Swerdlow RH,
Van Eldik LJ,
Paulson HL,
Trojanowski JQ,
Chui HC,
Rosenberg RN,
Craft S,
Grabowski TJ,
Asthana S,
Morris JC,
Strittmatter SM,
Kukull WA</span><br />
<span class="medgenPMjournal">JAMA Neurol</span>
2021 Jan 1;78(1):102-113.
doi: 10.1001/jamaneurol.2020.3536.
<span class="bold">PMID: </span><a href="/pubmed/33074286" target="_blank">33074286</a><a href="/pmc/articles/PMC7573798" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31755958">Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blauwendraat C,
Reed X,
Krohn L,
Heilbron K,
Bandres-Ciga S,
Tan M,
Gibbs JR,
Hernandez DG,
Kumaran R,
Langston R,
Bonet-Ponce L,
Alcalay RN,
Hassin-Baer S,
Greenbaum L,
Iwaki H,
Leonard HL,
Grenn FP,
Ruskey JA,
Sabir M,
Ahmed S,
Makarious MB,
Pihlstrøm L,
Toft M,
van Hilten JJ,
Marinus J,
Schulte C,
Brockmann K,
Sharma M,
Siitonen A,
Majamaa K,
Eerola-Rautio J,
Tienari PJ;
23andMe Research Team,
Pantelyat A,
Hillis AE,
Dawson TM,
Rosenthal LS,
Albert MS,
Resnick SM,
Ferrucci L,
Morris CM,
Pletnikova O,
Troncoso J,
Grosset D,
Lesage S,
Corvol JC,
Brice A,
Noyce AJ,
Masliah E,
Wood N,
Hardy J,
Shulman LM,
Jankovic J,
Shulman JM,
Heutink P,
Gasser T,
Cannon P,
Scholz SW,
Morris H,
Cookson MR,
Nalls MA,
Gan-Or Z,
Singleton AB</span><br />
<span class="medgenPMjournal">Brain</span>
2020 Jan 1;143(1):234-248.
doi: 10.1093/brain/awz350.
<span class="bold">PMID: </span><a href="/pubmed/31755958" target="_blank">31755958</a><a href="/pmc/articles/PMC6935749" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27098668">Olfactory dysfunction is related to postoperative delirium in Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kim MS,
Yoon JH,
Kim HJ,
Yong SW,
Hong JM</span><br />
<span class="medgenPMjournal">J Neural Transm (Vienna)</span>
2016 Jun;123(6):589-94.
Epub 2016 Apr 20
doi: 10.1007/s00702-016-1555-0.
<span class="bold">PMID: </span><a href="/pubmed/27098668" target="_blank">27098668</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dementia%2C%20Lewy%20body%2C%20susceptibility%20to%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (87)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/38801432">Loss of the "swallow tail sign" on susceptibility-weighted imaging in the diagnosis of dementia with Lewy bodies: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tseriotis VS,
Mavridis T,
Eleftheriadou K,
Konstantis G,
Chlorogiannis DD,
Pavlidis P,
Pourzitaki C,
Arnaoutoglou M,
Spyridon K</span><br />
<span class="medgenPMjournal">J Neurol</span>
2024 Jul;271(7):3754-3763.
Epub 2024 May 27
doi: 10.1007/s00415-024-12381-6.
<span class="bold">PMID: </span><a href="/pubmed/38801432" target="_blank">38801432</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36281704">Challenges in diagnosis and management of delirium in Lewy body disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Richardson S,
Lawson RA,
Price A,
Taylor JP</span><br />
<span class="medgenPMjournal">Acta Psychiatr Scand</span>
2023 May;147(5):475-480.
Epub 2022 Nov 4
doi: 10.1111/acps.13514.
<span class="bold">PMID: </span><a href="/pubmed/36281704" target="_blank">36281704</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35643264">Fractal dimension of the brain in neurodegenerative disease and dementia: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ziukelis ET,
Mak E,
Dounavi ME,
Su L,
T O'Brien J</span><br />
<span class="medgenPMjournal">Ageing Res Rev</span>
2022 Aug;79:101651.
Epub 2022 May 25
doi: 10.1016/j.arr.2022.101651.
<span class="bold">PMID: </span><a href="/pubmed/35643264" target="_blank">35643264</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35040520">Infectious Agents as Potential Drivers of α-Synucleinopathies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Linard M,
Ravier A,
Mougué L,
Grgurina I,
Boutillier AL,
Foubert-Samier A,
Blanc F,
Helmer C</span><br />
<span class="medgenPMjournal">Mov Disord</span>
2022 Mar;37(3):464-477.
Epub 2022 Jan 18
doi: 10.1002/mds.28925.
<span class="bold">PMID: </span><a href="/pubmed/35040520" target="_blank">35040520</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24805970">Genetics in degenerative dementia: current status and applicability.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bruni AC,
Conidi ME,
Bernardi L</span><br />
<span class="medgenPMjournal">Alzheimer Dis Assoc Disord</span>
2014 Jul-Sep;28(3):199-205.
doi: 10.1097/WAD.0000000000000046.
<span class="bold">PMID: </span><a href="/pubmed/24805970" target="_blank">24805970</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dementia%2C%20Lewy%20body%2C%20susceptibility%20to%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (12)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C2676021%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
<li><a href="/gtr/tests?term=C2676021%5bDISCUI%5d&amp;filter=method%3A2%5F18" target="_blank">Mutation scanning of select exons (1)</a></li>
<li><a href="/gtr/tests?term=C2676021%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (1)</a></li>
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C2676021%5bDISCUI%5d" target="_blank">See all (1)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Dementia,%20Lewy%20body,%20susceptibility%20to" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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