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<meta name="keywords" content="C2674838, acute alcohol sensitivity, alcohol intolerance, alcohol sensitivity, acute, aldh2, finding, hangover, susceptibility to, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Alcohol intolerance is characterized by immediate unpleasant reactions after drinking alcohol. The most common signs and symptoms of alcohol intolerance are stuffy nose and skin flushing. Alcohol intolerance is caused by a genetic condition in which the body is unable to break down alcohol efficiently, usually found in Asians. These individuals accumulate acetaldehyde, the primary metabolite of ethanol, because of a genetic polymorphism of aldehyde dehydrogenase (ALDH) that metabolizes acetaldehyde to nontoxic acetate. The only way to prevent alcohol intolerance reactions is to avoid alcohol. Alcohol intolerance isn't an allergy. However, in some cases, what seems to be alcohol intolerance may be a reaction to something in an alcoholic beverage, such as chemicals, grains or preservatives. Combining alcohol with certain medications also can cause reactions. In rare instances, an unpleasant reaction to alcohol can be a sign of a serious underlying health problem that requires diagnosis and treatment." /><meta name="robots" content="index,nofollow,noarchive" />
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||
<!--
|
||
UID=390639
|
||
ConceptID=C2674838
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Alcohol sensitivity, acute</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>390639</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C2674838</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>ALCOHOL SENSITIVITY, ACUTE</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="ALDH2 - ID: 217 - NCBI Gene" href="/gene/217" class="medgenPMinfo">ALDH2</a> (12q24.12)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0012454" target="_blank">MONDO:0012454</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/610251" target="_blank">610251</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Alcohol intolerance is characterized by immediate unpleasant reactions after drinking alcohol. The most common signs and symptoms of alcohol intolerance are stuffy nose and skin flushing. Alcohol intolerance is caused by a genetic condition in which the body is unable to break down alcohol efficiently, usually found in Asians. These individuals accumulate acetaldehyde, the primary metabolite of ethanol, because of a genetic polymorphism of aldehyde dehydrogenase (ALDH) that metabolizes acetaldehyde to nontoxic acetate. The only way to prevent alcohol intolerance reactions is to avoid alcohol. Alcohol intolerance isn't an allergy. However, in some cases, what seems to be alcohol intolerance may be a reaction to something in an alcoholic beverage, such as chemicals, grains or preservatives. Combining alcohol with certain medications also can cause reactions. In rare instances, an unpleasant reaction to alcohol can be a sign of a serious underlying health problem that requires diagnosis and treatment. [from <a title="Monarch Initiative" href="https://monarchinitiative.org/" class="defSource" target="_blank">MONDO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_871130"><div><strong>Reduced acetaldehyde dehydrogenase level</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>871130</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4025601</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Decreased level of acetaldehyde dehydrogenase (ALDH). ALDH and alcohol dehydrogenase (ADH) are the primary enzymes involved in alcohol metabolism.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/871130">Feature record</a> | <a href="/medgen?term=%22Reduced%20acetaldehyde%20dehydrogenase%20level%22%5BClinical%20Features%5D%20OR%20871130%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_871320"><div><strong>Facial flushing after alcohol intake</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>871320</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4025808</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/871320">Feature record</a> | <a href="/medgen?term=%22Facial%20flushing%20after%20alcohol%20intake%22%5BClinical%20Features%5D%20OR%20871320%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of metabolism/homeostasis</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_871130" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Reduced acetaldehyde dehydrogenase level</a></span></li></ul></li><li><span class="TLline">Abnormality of the integument</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_871320" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Facial flushing after alcohol intake</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36802976">Initial Diagnosis and Management of Acutely Elevated Intracranial Pressure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kareemi H,
|
||
Pratte M,
|
||
English S,
|
||
Hendin A</span><br />
|
||
<span class="medgenPMjournal">J Intensive Care Med</span>
|
||
2023 Jul;38(7):643-650.
|
||
Epub 2023 Feb 19
|
||
doi: 10.1177/08850666231156589.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36802976" target="_blank">36802976</a><a href="/pmc/articles/PMC10302390" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32710772">Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fregni F,
|
||
El-Hagrassy MM,
|
||
Pacheco-Barrios K,
|
||
Carvalho S,
|
||
Leite J,
|
||
Simis M,
|
||
Brunelin J,
|
||
Nakamura-Palacios EM,
|
||
Marangolo P,
|
||
Venkatasubramanian G,
|
||
San-Juan D,
|
||
Caumo W,
|
||
Bikson M,
|
||
Brunoni AR;
|
||
Neuromodulation Center Working Group</span><br />
|
||
<span class="medgenPMjournal">Int J Neuropsychopharmacol</span>
|
||
2021 Apr 21;24(4):256-313.
|
||
doi: 10.1093/ijnp/pyaa051.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32710772" target="_blank">32710772</a><a href="/pmc/articles/PMC8059493" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19454881">Foods and supplements in the management of migraine headaches.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sun-Edelstein C,
|
||
Mauskop A</span><br />
|
||
<span class="medgenPMjournal">Clin J Pain</span>
|
||
2009 Jun;25(5):446-52.
|
||
doi: 10.1097/AJP.0b013e31819a6f65.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19454881" target="_blank">19454881</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(alcohol%20sensitivity%2C%20acute)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (83)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37394255">Evaluation and Management of Food Allergies in the Emergency Department.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krajewski GS,
|
||
Krajewski T</span><br />
|
||
<span class="medgenPMjournal">Immunol Allergy Clin North Am</span>
|
||
2023 Aug;43(3):491-501.
|
||
doi: 10.1016/j.iac.2022.10.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37394255" target="_blank">37394255</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36528936">ALDH2 deficiency increases susceptibility to binge alcohol-induced gut leakiness, endotoxemia, and acute liver injury in mice through the gut-liver axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rungratanawanich W,
|
||
Lin Y,
|
||
Wang X,
|
||
Kawamoto T,
|
||
Chidambaram SB,
|
||
Song BJ</span><br />
|
||
<span class="medgenPMjournal">Redox Biol</span>
|
||
2023 Feb;59:102577.
|
||
Epub 2022 Dec 13
|
||
doi: 10.1016/j.redox.2022.102577.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36528936" target="_blank">36528936</a><a href="/pmc/articles/PMC9792909" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35325064">Biomarkers and Clinical Laboratory Detection of Acute and Chronic Ethanol Use.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tawiah KD,
|
||
Riley SB,
|
||
Budelier MM</span><br />
|
||
<span class="medgenPMjournal">Clin Chem</span>
|
||
2022 May 18;68(5):635-645.
|
||
doi: 10.1093/clinchem/hvac004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35325064" target="_blank">35325064</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34782091">Evaluation and Management of Food Allergies in the Emergency Department.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krajewski GS,
|
||
Krajewski T</span><br />
|
||
<span class="medgenPMjournal">Emerg Med Clin North Am</span>
|
||
2022 Feb;40(1):57-67.
|
||
Epub 2021 Oct 29
|
||
doi: 10.1016/j.emc.2021.08.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34782091" target="_blank">34782091</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30167704">Will This Hospitalized Patient Develop Severe Alcohol Withdrawal Syndrome?: The Rational Clinical Examination Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wood E,
|
||
Albarqouni L,
|
||
Tkachuk S,
|
||
Green CJ,
|
||
Ahamad K,
|
||
Nolan S,
|
||
McLean M,
|
||
Klimas J</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2018 Aug 28;320(8):825-833.
|
||
doi: 10.1001/jama.2018.10574.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30167704" target="_blank">30167704</a><a href="/pmc/articles/PMC6905615" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alcohol%20sensitivity%2C%20acute%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1053)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36528936">ALDH2 deficiency increases susceptibility to binge alcohol-induced gut leakiness, endotoxemia, and acute liver injury in mice through the gut-liver axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rungratanawanich W,
|
||
Lin Y,
|
||
Wang X,
|
||
Kawamoto T,
|
||
Chidambaram SB,
|
||
Song BJ</span><br />
|
||
<span class="medgenPMjournal">Redox Biol</span>
|
||
2023 Feb;59:102577.
|
||
Epub 2022 Dec 13
|
||
doi: 10.1016/j.redox.2022.102577.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36528936" target="_blank">36528936</a><a href="/pmc/articles/PMC9792909" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34320661">Drug-induced Myopathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Steinmeyer J,
|
||
Flechtenmacher J</span><br />
|
||
<span class="medgenPMjournal">Z Orthop Unfall</span>
|
||
2023 Apr;161(2):175-181.
|
||
Epub 2021 Jul 28
|
||
doi: 10.1055/a-1488-6912.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34320661" target="_blank">34320661</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30580553">n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang M,
|
||
Ma LJ,
|
||
Yang Y,
|
||
Xiao Z,
|
||
Wan JB</span><br />
|
||
<span class="medgenPMjournal">Crit Rev Food Sci Nutr</span>
|
||
2019;59(sup1):S116-S129.
|
||
Epub 2018 Dec 22
|
||
doi: 10.1080/10408398.2018.1544542.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30580553" target="_blank">30580553</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30167704">Will This Hospitalized Patient Develop Severe Alcohol Withdrawal Syndrome?: The Rational Clinical Examination Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wood E,
|
||
Albarqouni L,
|
||
Tkachuk S,
|
||
Green CJ,
|
||
Ahamad K,
|
||
Nolan S,
|
||
McLean M,
|
||
Klimas J</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2018 Aug 28;320(8):825-833.
|
||
doi: 10.1001/jama.2018.10574.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30167704" target="_blank">30167704</a><a href="/pmc/articles/PMC6905615" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1679209">The benzodiazepines: anxiolytic and withdrawal effects.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Little HJ</span><br />
|
||
<span class="medgenPMjournal">Neuropeptides</span>
|
||
1991 Jul;19 Suppl:11-4.
|
||
doi: 10.1016/0143-4179(91)90077-v.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1679209" target="_blank">1679209</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alcohol%20sensitivity%2C%20acute%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2195)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36802976">Initial Diagnosis and Management of Acutely Elevated Intracranial Pressure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kareemi H,
|
||
Pratte M,
|
||
English S,
|
||
Hendin A</span><br />
|
||
<span class="medgenPMjournal">J Intensive Care Med</span>
|
||
2023 Jul;38(7):643-650.
|
||
Epub 2023 Feb 19
|
||
doi: 10.1177/08850666231156589.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36802976" target="_blank">36802976</a><a href="/pmc/articles/PMC10302390" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34320661">Drug-induced Myopathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Steinmeyer J,
|
||
Flechtenmacher J</span><br />
|
||
<span class="medgenPMjournal">Z Orthop Unfall</span>
|
||
2023 Apr;161(2):175-181.
|
||
Epub 2021 Jul 28
|
||
doi: 10.1055/a-1488-6912.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34320661" target="_blank">34320661</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31178367">Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Furukawa TA,
|
||
Cipriani A,
|
||
Cowen PJ,
|
||
Leucht S,
|
||
Egger M,
|
||
Salanti G</span><br />
|
||
<span class="medgenPMjournal">Lancet Psychiatry</span>
|
||
2019 Jul;6(7):601-609.
|
||
Epub 2019 Jun 6
|
||
doi: 10.1016/S2215-0366(19)30217-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31178367" target="_blank">31178367</a><a href="/pmc/articles/PMC6586944" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30167704">Will This Hospitalized Patient Develop Severe Alcohol Withdrawal Syndrome?: The Rational Clinical Examination Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wood E,
|
||
Albarqouni L,
|
||
Tkachuk S,
|
||
Green CJ,
|
||
Ahamad K,
|
||
Nolan S,
|
||
McLean M,
|
||
Klimas J</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2018 Aug 28;320(8):825-833.
|
||
doi: 10.1001/jama.2018.10574.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30167704" target="_blank">30167704</a><a href="/pmc/articles/PMC6905615" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11368286">Levosimendan.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Figgitt DP,
|
||
Gillies PS,
|
||
Goa KL</span><br />
|
||
<span class="medgenPMjournal">Drugs</span>
|
||
2001;61(5):613-27; discussion 628-9.
|
||
doi: 10.2165/00003495-200161050-00006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11368286" target="_blank">11368286</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alcohol%20sensitivity%2C%20acute%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1032)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34711928">Association study of candidate DNA-repair gene variants and acute graft versus host disease in pediatric patients receiving allogeneic hematopoietic stem-cell transplantation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Uppugunduri CRS,
|
||
Huezo-Diaz Curtis P,
|
||
Nava T,
|
||
Rezgui MA,
|
||
Mlakar V,
|
||
Mlakar SJ,
|
||
Waespe N,
|
||
Théoret Y,
|
||
Gumy-Pause F,
|
||
Bernard F,
|
||
Chalandon Y,
|
||
Boelens JJ,
|
||
Bredius RGM,
|
||
Dalle JH,
|
||
Nath C,
|
||
Corbacioglu S,
|
||
Peters C,
|
||
Bader P,
|
||
Shaw P,
|
||
Bittencourt H,
|
||
Krajinovic M,
|
||
Ansari M</span><br />
|
||
<span class="medgenPMjournal">Pharmacogenomics J</span>
|
||
2022 Feb;22(1):9-18.
|
||
Epub 2021 Oct 28
|
||
doi: 10.1038/s41397-021-00251-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34711928" target="_blank">34711928</a><a href="/pmc/articles/PMC8794787" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32281608">Case series: Fulminant community-acquired Acinetobacter pneumonia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonnii S,
|
||
Chua HH</span><br />
|
||
<span class="medgenPMjournal">Med J Malaysia</span>
|
||
2020 Mar;75(2):186-188.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32281608" target="_blank">32281608</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30167704">Will This Hospitalized Patient Develop Severe Alcohol Withdrawal Syndrome?: The Rational Clinical Examination Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wood E,
|
||
Albarqouni L,
|
||
Tkachuk S,
|
||
Green CJ,
|
||
Ahamad K,
|
||
Nolan S,
|
||
McLean M,
|
||
Klimas J</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2018 Aug 28;320(8):825-833.
|
||
doi: 10.1001/jama.2018.10574.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30167704" target="_blank">30167704</a><a href="/pmc/articles/PMC6905615" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20975548">Fluid resuscitation in septic shock: a positive fluid balance and elevated central venous pressure are associated with increased mortality.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boyd JH,
|
||
Forbes J,
|
||
Nakada TA,
|
||
Walley KR,
|
||
Russell JA</span><br />
|
||
<span class="medgenPMjournal">Crit Care Med</span>
|
||
2011 Feb;39(2):259-65.
|
||
doi: 10.1097/CCM.0b013e3181feeb15.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20975548" target="_blank">20975548</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16863435">Cardiac troponins as biomarkers of drug- and toxin-induced cardiac toxicity and cardioprotection.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gaze DC,
|
||
Collinson PO</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Drug Metab Toxicol</span>
|
||
2005 Dec;1(4):715-25.
|
||
doi: 10.1517/17425255.1.4.715.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16863435" target="_blank">16863435</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alcohol%20sensitivity%2C%20acute%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (716)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36528936">ALDH2 deficiency increases susceptibility to binge alcohol-induced gut leakiness, endotoxemia, and acute liver injury in mice through the gut-liver axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rungratanawanich W,
|
||
Lin Y,
|
||
Wang X,
|
||
Kawamoto T,
|
||
Chidambaram SB,
|
||
Song BJ</span><br />
|
||
<span class="medgenPMjournal">Redox Biol</span>
|
||
2023 Feb;59:102577.
|
||
Epub 2022 Dec 13
|
||
doi: 10.1016/j.redox.2022.102577.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36528936" target="_blank">36528936</a><a href="/pmc/articles/PMC9792909" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30167704">Will This Hospitalized Patient Develop Severe Alcohol Withdrawal Syndrome?: The Rational Clinical Examination Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wood E,
|
||
Albarqouni L,
|
||
Tkachuk S,
|
||
Green CJ,
|
||
Ahamad K,
|
||
Nolan S,
|
||
McLean M,
|
||
Klimas J</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2018 Aug 28;320(8):825-833.
|
||
doi: 10.1001/jama.2018.10574.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30167704" target="_blank">30167704</a><a href="/pmc/articles/PMC6905615" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24851074">Acute esophageal necrosis occurring in a patient undergoing percutaneous coronary intervention.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kwon HJ,
|
||
Park SH,
|
||
Ahn JH,
|
||
Lee TH,
|
||
Lee CK</span><br />
|
||
<span class="medgenPMjournal">Korean J Intern Med</span>
|
||
2014 May;29(3):379-82.
|
||
Epub 2014 Apr 29
|
||
doi: 10.3904/kjim.2014.29.3.379.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24851074" target="_blank">24851074</a><a href="/pmc/articles/PMC4028529" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24291291">Adolescents and alcohol: acute sensitivities, enhanced intake, and later consequences.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Spear LP</span><br />
|
||
<span class="medgenPMjournal">Neurotoxicol Teratol</span>
|
||
2014 Jan-Feb;41:51-9.
|
||
Epub 2013 Nov 26
|
||
doi: 10.1016/j.ntt.2013.11.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24291291" target="_blank">24291291</a><a href="/pmc/articles/PMC3943972" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12562165">Adrenergic contribution during acclimatization to high altitude: perspectives from Pikes Peak.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mazzeo RS,
|
||
Reeves JT</span><br />
|
||
<span class="medgenPMjournal">Exerc Sport Sci Rev</span>
|
||
2003 Jan;31(1):13-8.
|
||
doi: 10.1097/00003677-200301000-00004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12562165" target="_blank">12562165</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alcohol%20sensitivity%2C%20acute%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (979)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/33436495">Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mezzano G,
|
||
Juanola A,
|
||
Cardenas A,
|
||
Mezey E,
|
||
Hamilton JP,
|
||
Pose E,
|
||
Graupera I,
|
||
Ginès P,
|
||
Solà E,
|
||
Hernaez R</span><br />
|
||
<span class="medgenPMjournal">Gut</span>
|
||
2022 Jan;71(1):148-155.
|
||
Epub 2021 Jan 12
|
||
doi: 10.1136/gutjnl-2020-322161.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33436495" target="_blank">33436495</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32710772">Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fregni F,
|
||
El-Hagrassy MM,
|
||
Pacheco-Barrios K,
|
||
Carvalho S,
|
||
Leite J,
|
||
Simis M,
|
||
Brunelin J,
|
||
Nakamura-Palacios EM,
|
||
Marangolo P,
|
||
Venkatasubramanian G,
|
||
San-Juan D,
|
||
Caumo W,
|
||
Bikson M,
|
||
Brunoni AR;
|
||
Neuromodulation Center Working Group</span><br />
|
||
<span class="medgenPMjournal">Int J Neuropsychopharmacol</span>
|
||
2021 Apr 21;24(4):256-313.
|
||
doi: 10.1093/ijnp/pyaa051.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32710772" target="_blank">32710772</a><a href="/pmc/articles/PMC8059493" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31178367">Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Furukawa TA,
|
||
Cipriani A,
|
||
Cowen PJ,
|
||
Leucht S,
|
||
Egger M,
|
||
Salanti G</span><br />
|
||
<span class="medgenPMjournal">Lancet Psychiatry</span>
|
||
2019 Jul;6(7):601-609.
|
||
Epub 2019 Jun 6
|
||
doi: 10.1016/S2215-0366(19)30217-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31178367" target="_blank">31178367</a><a href="/pmc/articles/PMC6586944" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31161524">Exocrine Pancreatic Insufficiency Following Acute Pancreatitis: Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang W,
|
||
de la Iglesia-García D,
|
||
Baston-Rey I,
|
||
Calviño-Suarez C,
|
||
Lariño-Noia J,
|
||
Iglesias-Garcia J,
|
||
Shi N,
|
||
Zhang X,
|
||
Cai W,
|
||
Deng L,
|
||
Moore D,
|
||
Singh VK,
|
||
Xia Q,
|
||
Windsor JA,
|
||
Domínguez-Muñoz JE,
|
||
Sutton R</span><br />
|
||
<span class="medgenPMjournal">Dig Dis Sci</span>
|
||
2019 Jul;64(7):1985-2005.
|
||
Epub 2019 Jun 4
|
||
doi: 10.1007/s10620-019-05568-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31161524" target="_blank">31161524</a><a href="/pmc/articles/PMC6584228" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30167704">Will This Hospitalized Patient Develop Severe Alcohol Withdrawal Syndrome?: The Rational Clinical Examination Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wood E,
|
||
Albarqouni L,
|
||
Tkachuk S,
|
||
Green CJ,
|
||
Ahamad K,
|
||
Nolan S,
|
||
McLean M,
|
||
Klimas J</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2018 Aug 28;320(8):825-833.
|
||
doi: 10.1001/jama.2018.10574.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30167704" target="_blank">30167704</a><a href="/pmc/articles/PMC6905615" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alcohol%20sensitivity%2C%20acute%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (39)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
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</div>
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|
||
<div class="portlet mgSection" id="ID_106">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C2674838%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (7)</a></li>
|
||
<li><a href="/gtr/tests?term=C2674838%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (11)</a></li>
|
||
<li><a href="/gtr/tests?term=C2674838%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (1)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C2674838%5bDISCUI%5d" target="_blank">See all (13)</a></total></li>
|
||
</ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_119">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=610251" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Alcohol%20sensitivity,%20acute" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(alcohol%20sensitivity%2C%20acute)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Alcohol%20sensitivity%2C%20acute%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_115">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=100650" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=217[geneid]" target="_blank">View ALDH2 variations in ClinVar</a></li><li><a href="/nuccore/238776813" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=610251" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_116">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.diseaseinfosearch.org/Acute+alcohol+sensitivity/7630" target="_blank">Genetic Alliance</a></li><li><a href="https://www.malacards.org/card/alcohol_sensitivity_acute" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Alcohol%20sensitivity,%20acute" target="_blank">MedlinePlus</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/12634/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
</div>
|
||
</div>
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
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||
<h3>Reviews</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
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||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pubmed/clinical?term=Alcohol%20sensitivity,%20acute" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed?term=Alcohol%20sensitivity,%20acute%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<!-- MedGen supplemental column ends here -->
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=390639" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=medgen_gene_diseases&from_uid=390639" ref="log$=recordlinks">Gene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in NCBI Gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C2674838[DISCUI]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C2674838[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&from_uid=390639" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
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<a href="https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/@38.9959508,-77.101021,17z/data=!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb:0x19156f88b27635b8!8m2!3d38.9959508!4d-77.0988323" class="text-white" target="_blank" rel="noopener noreferrer">8600 Rockville Pike<br />
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Bethesda, MD 20894</a></p>
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<p><a href="https://www.nlm.nih.gov/web_policies.html" class="text-white">Web Policies</a><br />
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