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<meta name="keywords" content="C1863053, alzheimer disease, early-onset, with cerebral amyloid angiopathy, disease or syndrome, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="" /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Alzheimer disease, early-onset, with cerebral amyloid angiopathy (Concept Id: C1863053)
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<!--
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||
UID=400198
|
||
ConceptID=C1863053
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Alzheimer disease, early-onset, with cerebral amyloid angiopathy</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>400198</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1863053</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/104300" target="_blank">104300</a>; <a href="https://omim.org/entry/104760" target="_blank">104760</a></td></tr>
|
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37931443">Exploring cerebral amyloid angiopathy: Insights into pathogenesis, diagnosis, and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cozza M,
|
||
Amadori L,
|
||
Boccardi V</span><br />
|
||
<span class="medgenPMjournal">J Neurol Sci</span>
|
||
2023 Nov 15;454:120866.
|
||
Epub 2023 Nov 2
|
||
doi: 10.1016/j.jns.2023.120866.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37931443" target="_blank">37931443</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35841910">The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Charidimou A,
|
||
Boulouis G,
|
||
Frosch MP,
|
||
Baron JC,
|
||
Pasi M,
|
||
Albucher JF,
|
||
Banerjee G,
|
||
Barbato C,
|
||
Bonneville F,
|
||
Brandner S,
|
||
Calviere L,
|
||
Caparros F,
|
||
Casolla B,
|
||
Cordonnier C,
|
||
Delisle MB,
|
||
Deramecourt V,
|
||
Dichgans M,
|
||
Gokcal E,
|
||
Herms J,
|
||
Hernandez-Guillamon M,
|
||
Jäger HR,
|
||
Jaunmuktane Z,
|
||
Linn J,
|
||
Martinez-Ramirez S,
|
||
Martínez-Sáez E,
|
||
Mawrin C,
|
||
Montaner J,
|
||
Moulin S,
|
||
Olivot JM,
|
||
Piazza F,
|
||
Puy L,
|
||
Raposo N,
|
||
Rodrigues MA,
|
||
Roeber S,
|
||
Romero JR,
|
||
Samarasekera N,
|
||
Schneider JA,
|
||
Schreiber S,
|
||
Schreiber F,
|
||
Schwall C,
|
||
Smith C,
|
||
Szalardy L,
|
||
Varlet P,
|
||
Viguier A,
|
||
Wardlaw JM,
|
||
Warren A,
|
||
Wollenweber FA,
|
||
Zedde M,
|
||
van Buchem MA,
|
||
Gurol ME,
|
||
Viswanathan A,
|
||
Al-Shahi Salman R,
|
||
Smith EE,
|
||
Werring DJ,
|
||
Greenberg SM</span><br />
|
||
<span class="medgenPMjournal">Lancet Neurol</span>
|
||
2022 Aug;21(8):714-725.
|
||
doi: 10.1016/S1474-4422(22)00208-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35841910" target="_blank">35841910</a><a href="/pmc/articles/PMC9389452" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26720093">Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Auriel E,
|
||
Charidimou A,
|
||
Gurol ME,
|
||
Ni J,
|
||
Van Etten ES,
|
||
Martinez-Ramirez S,
|
||
Boulouis G,
|
||
Piazza F,
|
||
DiFrancesco JC,
|
||
Frosch MP,
|
||
Pontes-Neto OV,
|
||
Shoamanesh A,
|
||
Reijmer Y,
|
||
Vashkevich A,
|
||
Ayres AM,
|
||
Schwab KM,
|
||
Viswanathan A,
|
||
Greenberg SM</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2016 Feb;73(2):197-202.
|
||
doi: 10.1001/jamaneurol.2015.4078.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26720093" target="_blank">26720093</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (42)</a></div></div>
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|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37434208">Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Inoue Y,
|
||
Shue F,
|
||
Bu G,
|
||
Kanekiyo T</span><br />
|
||
<span class="medgenPMjournal">Mol Neurodegener</span>
|
||
2023 Jul 11;18(1):46.
|
||
doi: 10.1186/s13024-023-00640-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37434208" target="_blank">37434208</a><a href="/pmc/articles/PMC10334598" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37280110">Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hampel H,
|
||
Elhage A,
|
||
Cho M,
|
||
Apostolova LG,
|
||
Nicoll JAR,
|
||
Atri A</span><br />
|
||
<span class="medgenPMjournal">Brain</span>
|
||
2023 Nov 2;146(11):4414-4424.
|
||
doi: 10.1093/brain/awad188.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37280110" target="_blank">37280110</a><a href="/pmc/articles/PMC10629981" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35841910">The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Charidimou A,
|
||
Boulouis G,
|
||
Frosch MP,
|
||
Baron JC,
|
||
Pasi M,
|
||
Albucher JF,
|
||
Banerjee G,
|
||
Barbato C,
|
||
Bonneville F,
|
||
Brandner S,
|
||
Calviere L,
|
||
Caparros F,
|
||
Casolla B,
|
||
Cordonnier C,
|
||
Delisle MB,
|
||
Deramecourt V,
|
||
Dichgans M,
|
||
Gokcal E,
|
||
Herms J,
|
||
Hernandez-Guillamon M,
|
||
Jäger HR,
|
||
Jaunmuktane Z,
|
||
Linn J,
|
||
Martinez-Ramirez S,
|
||
Martínez-Sáez E,
|
||
Mawrin C,
|
||
Montaner J,
|
||
Moulin S,
|
||
Olivot JM,
|
||
Piazza F,
|
||
Puy L,
|
||
Raposo N,
|
||
Rodrigues MA,
|
||
Roeber S,
|
||
Romero JR,
|
||
Samarasekera N,
|
||
Schneider JA,
|
||
Schreiber S,
|
||
Schreiber F,
|
||
Schwall C,
|
||
Smith C,
|
||
Szalardy L,
|
||
Varlet P,
|
||
Viguier A,
|
||
Wardlaw JM,
|
||
Warren A,
|
||
Wollenweber FA,
|
||
Zedde M,
|
||
van Buchem MA,
|
||
Gurol ME,
|
||
Viswanathan A,
|
||
Al-Shahi Salman R,
|
||
Smith EE,
|
||
Werring DJ,
|
||
Greenberg SM</span><br />
|
||
<span class="medgenPMjournal">Lancet Neurol</span>
|
||
2022 Aug;21(8):714-725.
|
||
doi: 10.1016/S1474-4422(22)00208-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35841910" target="_blank">35841910</a><a href="/pmc/articles/PMC9389452" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35678401">Vascular Cognitive Impairment and Dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chang Wong E,
|
||
Chang Chui H</span><br />
|
||
<span class="medgenPMjournal">Continuum (Minneap Minn)</span>
|
||
2022 Jun 1;28(3):750-780.
|
||
doi: 10.1212/CON.0000000000001124.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35678401" target="_blank">35678401</a><a href="/pmc/articles/PMC9833847" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20831921">Alzheimer disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Castellani RJ,
|
||
Rolston RK,
|
||
Smith MA</span><br />
|
||
<span class="medgenPMjournal">Dis Mon</span>
|
||
2010 Sep;56(9):484-546.
|
||
doi: 10.1016/j.disamonth.2010.06.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20831921" target="_blank">20831921</a><a href="/pmc/articles/PMC2941917" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (684)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37434208">Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Inoue Y,
|
||
Shue F,
|
||
Bu G,
|
||
Kanekiyo T</span><br />
|
||
<span class="medgenPMjournal">Mol Neurodegener</span>
|
||
2023 Jul 11;18(1):46.
|
||
doi: 10.1186/s13024-023-00640-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37434208" target="_blank">37434208</a><a href="/pmc/articles/PMC10334598" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35841910">The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Charidimou A,
|
||
Boulouis G,
|
||
Frosch MP,
|
||
Baron JC,
|
||
Pasi M,
|
||
Albucher JF,
|
||
Banerjee G,
|
||
Barbato C,
|
||
Bonneville F,
|
||
Brandner S,
|
||
Calviere L,
|
||
Caparros F,
|
||
Casolla B,
|
||
Cordonnier C,
|
||
Delisle MB,
|
||
Deramecourt V,
|
||
Dichgans M,
|
||
Gokcal E,
|
||
Herms J,
|
||
Hernandez-Guillamon M,
|
||
Jäger HR,
|
||
Jaunmuktane Z,
|
||
Linn J,
|
||
Martinez-Ramirez S,
|
||
Martínez-Sáez E,
|
||
Mawrin C,
|
||
Montaner J,
|
||
Moulin S,
|
||
Olivot JM,
|
||
Piazza F,
|
||
Puy L,
|
||
Raposo N,
|
||
Rodrigues MA,
|
||
Roeber S,
|
||
Romero JR,
|
||
Samarasekera N,
|
||
Schneider JA,
|
||
Schreiber S,
|
||
Schreiber F,
|
||
Schwall C,
|
||
Smith C,
|
||
Szalardy L,
|
||
Varlet P,
|
||
Viguier A,
|
||
Wardlaw JM,
|
||
Warren A,
|
||
Wollenweber FA,
|
||
Zedde M,
|
||
van Buchem MA,
|
||
Gurol ME,
|
||
Viswanathan A,
|
||
Al-Shahi Salman R,
|
||
Smith EE,
|
||
Werring DJ,
|
||
Greenberg SM</span><br />
|
||
<span class="medgenPMjournal">Lancet Neurol</span>
|
||
2022 Aug;21(8):714-725.
|
||
doi: 10.1016/S1474-4422(22)00208-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35841910" target="_blank">35841910</a><a href="/pmc/articles/PMC9389452" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35678401">Vascular Cognitive Impairment and Dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chang Wong E,
|
||
Chang Chui H</span><br />
|
||
<span class="medgenPMjournal">Continuum (Minneap Minn)</span>
|
||
2022 Jun 1;28(3):750-780.
|
||
doi: 10.1212/CON.0000000000001124.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35678401" target="_blank">35678401</a><a href="/pmc/articles/PMC9833847" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23296339">Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu CC,
|
||
Liu CC,
|
||
Kanekiyo T,
|
||
Xu H,
|
||
Bu G</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Neurol</span>
|
||
2013 Feb;9(2):106-18.
|
||
Epub 2013 Jan 8
|
||
doi: 10.1038/nrneurol.2012.263.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23296339" target="_blank">23296339</a><a href="/pmc/articles/PMC3726719" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22229116">Neuropathological alterations in Alzheimer disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Serrano-Pozo A,
|
||
Frosch MP,
|
||
Masliah E,
|
||
Hyman BT</span><br />
|
||
<span class="medgenPMjournal">Cold Spring Harb Perspect Med</span>
|
||
2011 Sep;1(1):a006189.
|
||
doi: 10.1101/cshperspect.a006189.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22229116" target="_blank">22229116</a><a href="/pmc/articles/PMC3234452" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (492)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38086820">Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Solopova E,
|
||
Romero-Fernandez W,
|
||
Harmsen H,
|
||
Ventura-Antunes L,
|
||
Wang E,
|
||
Shostak A,
|
||
Maldonado J,
|
||
Donahue MJ,
|
||
Schultz D,
|
||
Coyne TM,
|
||
Charidimou A,
|
||
Schrag M</span><br />
|
||
<span class="medgenPMjournal">Nat Commun</span>
|
||
2023 Dec 12;14(1):8220.
|
||
doi: 10.1038/s41467-023-43933-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38086820" target="_blank">38086820</a><a href="/pmc/articles/PMC10716177" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37280110">Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hampel H,
|
||
Elhage A,
|
||
Cho M,
|
||
Apostolova LG,
|
||
Nicoll JAR,
|
||
Atri A</span><br />
|
||
<span class="medgenPMjournal">Brain</span>
|
||
2023 Nov 2;146(11):4414-4424.
|
||
doi: 10.1093/brain/awad188.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37280110" target="_blank">37280110</a><a href="/pmc/articles/PMC10629981" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37125554">Neuropathology of Anti-Amyloid-β Immunotherapy: A Case Report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Castellani RJ,
|
||
Shanes ED,
|
||
McCord M,
|
||
Reish NJ,
|
||
Flanagan ME,
|
||
Mesulam MM,
|
||
Jamshidi P</span><br />
|
||
<span class="medgenPMjournal">J Alzheimers Dis</span>
|
||
2023;93(2):803-813.
|
||
doi: 10.3233/JAD-221305.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37125554" target="_blank">37125554</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34057813">Prevalence of cerebral amyloid angiopathy: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jäkel L,
|
||
De Kort AM,
|
||
Klijn CJM,
|
||
Schreuder FHBM,
|
||
Verbeek MM</span><br />
|
||
<span class="medgenPMjournal">Alzheimers Dement</span>
|
||
2022 Jan;18(1):10-28.
|
||
Epub 2021 May 31
|
||
doi: 10.1002/alz.12366.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34057813" target="_blank">34057813</a><a href="/pmc/articles/PMC9290643" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20831921">Alzheimer disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Castellani RJ,
|
||
Rolston RK,
|
||
Smith MA</span><br />
|
||
<span class="medgenPMjournal">Dis Mon</span>
|
||
2010 Sep;56(9):484-546.
|
||
doi: 10.1016/j.disamonth.2010.06.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20831921" target="_blank">20831921</a><a href="/pmc/articles/PMC2941917" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (168)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37280110">Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hampel H,
|
||
Elhage A,
|
||
Cho M,
|
||
Apostolova LG,
|
||
Nicoll JAR,
|
||
Atri A</span><br />
|
||
<span class="medgenPMjournal">Brain</span>
|
||
2023 Nov 2;146(11):4414-4424.
|
||
doi: 10.1093/brain/awad188.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37280110" target="_blank">37280110</a><a href="/pmc/articles/PMC10629981" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32130931">The Alzheimer's Disease Amyloid-Beta Hypothesis in Cardiovascular Aging and Disease: JACC Focus Seminar.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stakos DA,
|
||
Stamatelopoulos K,
|
||
Bampatsias D,
|
||
Sachse M,
|
||
Zormpas E,
|
||
Vlachogiannis NI,
|
||
Tual-Chalot S,
|
||
Stellos K</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2020 Mar 3;75(8):952-967.
|
||
doi: 10.1016/j.jacc.2019.12.033.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32130931" target="_blank">32130931</a><a href="/pmc/articles/PMC7042886" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29273521">The pathology and pathophysiology of vascular dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kalaria RN</span><br />
|
||
<span class="medgenPMjournal">Neuropharmacology</span>
|
||
2018 May 15;134(Pt B):226-239.
|
||
Epub 2017 Dec 19
|
||
doi: 10.1016/j.neuropharm.2017.12.030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29273521" target="_blank">29273521</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23296339">Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu CC,
|
||
Liu CC,
|
||
Kanekiyo T,
|
||
Xu H,
|
||
Bu G</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Neurol</span>
|
||
2013 Feb;9(2):106-18.
|
||
Epub 2013 Jan 8
|
||
doi: 10.1038/nrneurol.2012.263.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23296339" target="_blank">23296339</a><a href="/pmc/articles/PMC3726719" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20831921">Alzheimer disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Castellani RJ,
|
||
Rolston RK,
|
||
Smith MA</span><br />
|
||
<span class="medgenPMjournal">Dis Mon</span>
|
||
2010 Sep;56(9):484-546.
|
||
doi: 10.1016/j.disamonth.2010.06.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20831921" target="_blank">20831921</a><a href="/pmc/articles/PMC2941917" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (201)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37280110">Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hampel H,
|
||
Elhage A,
|
||
Cho M,
|
||
Apostolova LG,
|
||
Nicoll JAR,
|
||
Atri A</span><br />
|
||
<span class="medgenPMjournal">Brain</span>
|
||
2023 Nov 2;146(11):4414-4424.
|
||
doi: 10.1093/brain/awad188.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37280110" target="_blank">37280110</a><a href="/pmc/articles/PMC10629981" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36905365">Mass Spectrometry Imaging in Alzheimer's Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ikegawa M,
|
||
Kakuda N,
|
||
Miyasaka T,
|
||
Toyama Y,
|
||
Nirasawa T,
|
||
Minta K,
|
||
Hanrieder J</span><br />
|
||
<span class="medgenPMjournal">Brain Connect</span>
|
||
2023 Aug;13(6):319-333.
|
||
Epub 2023 Apr 24
|
||
doi: 10.1089/brain.2022.0057.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36905365" target="_blank">36905365</a><a href="/pmc/articles/PMC10494909" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34057813">Prevalence of cerebral amyloid angiopathy: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jäkel L,
|
||
De Kort AM,
|
||
Klijn CJM,
|
||
Schreuder FHBM,
|
||
Verbeek MM</span><br />
|
||
<span class="medgenPMjournal">Alzheimers Dement</span>
|
||
2022 Jan;18(1):10-28.
|
||
Epub 2021 May 31
|
||
doi: 10.1002/alz.12366.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34057813" target="_blank">34057813</a><a href="/pmc/articles/PMC9290643" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29273521">The pathology and pathophysiology of vascular dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kalaria RN</span><br />
|
||
<span class="medgenPMjournal">Neuropharmacology</span>
|
||
2018 May 15;134(Pt B):226-239.
|
||
Epub 2017 Dec 19
|
||
doi: 10.1016/j.neuropharm.2017.12.030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29273521" target="_blank">29273521</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23296339">Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu CC,
|
||
Liu CC,
|
||
Kanekiyo T,
|
||
Xu H,
|
||
Bu G</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Neurol</span>
|
||
2013 Feb;9(2):106-18.
|
||
Epub 2013 Jan 8
|
||
doi: 10.1038/nrneurol.2012.263.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23296339" target="_blank">23296339</a><a href="/pmc/articles/PMC3726719" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (574)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/35180115">Systematic Review on the Role of Lobar Cerebral Microbleeds in Cognition.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cipriano L,
|
||
Saracino D,
|
||
Oliva M,
|
||
Campana V,
|
||
Puoti G,
|
||
Conforti R,
|
||
Fulgione L,
|
||
Signoriello E,
|
||
Bonavita S,
|
||
Coppola C</span><br />
|
||
<span class="medgenPMjournal">J Alzheimers Dis</span>
|
||
2022;86(3):1025-1035.
|
||
doi: 10.3233/JAD-215323.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35180115" target="_blank">35180115</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34823269">Dysfunction of the blood-brain barrier in Alzheimer's disease: Evidence from human studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kurz C,
|
||
Walker L,
|
||
Rauchmann BS,
|
||
Perneczky R</span><br />
|
||
<span class="medgenPMjournal">Neuropathol Appl Neurobiol</span>
|
||
2022 Apr;48(3):e12782.
|
||
Epub 2022 Feb 2
|
||
doi: 10.1111/nan.12782.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34823269" target="_blank">34823269</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34057813">Prevalence of cerebral amyloid angiopathy: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jäkel L,
|
||
De Kort AM,
|
||
Klijn CJM,
|
||
Schreuder FHBM,
|
||
Verbeek MM</span><br />
|
||
<span class="medgenPMjournal">Alzheimers Dement</span>
|
||
2022 Jan;18(1):10-28.
|
||
Epub 2021 May 31
|
||
doi: 10.1002/alz.12366.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34057813" target="_blank">34057813</a><a href="/pmc/articles/PMC9290643" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28282807">Radiological-Pathological Correlation in Alzheimer's Disease: Systematic Review of Antemortem Magnetic Resonance Imaging Findings.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dallaire-Théroux C,
|
||
Callahan BL,
|
||
Potvin O,
|
||
Saikali S,
|
||
Duchesne S</span><br />
|
||
<span class="medgenPMjournal">J Alzheimers Dis</span>
|
||
2017;57(2):575-601.
|
||
doi: 10.3233/JAD-161028.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28282807" target="_blank">28282807</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23457231">Genetics of cerebral amyloid angiopathy: systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rannikmäe K,
|
||
Samarasekera N,
|
||
Martînez-Gonzâlez NA,
|
||
Al-Shahi Salman R,
|
||
Sudlow CL</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
2013 Aug;84(8):901-8.
|
||
Epub 2013 Mar 2
|
||
doi: 10.1136/jnnp-2012-303898.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23457231" target="_blank">23457231</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (11)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
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|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
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||
<div class="rightCol mgCol">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Alzheimer%20disease,%20early-onset,%20with%20cerebral%20amyloid%20angiopathy" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Alzheimer%20disease%2C%20early-onset%2C%20with%20cerebral%20amyloid%20angiopathy%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/alzheimer_disease_familial_1" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Alzheimer%20disease,%20early-onset,%20with%20cerebral%20amyloid%20angiopathy" target="_blank">MedlinePlus</a></li></ul></div>
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||
<div class="portlet_head">
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<div class="portlet_title">
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<h3>Reviews</h3>
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
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<ul>
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<li>
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<a href="/pubmed/clinical?term=Alzheimer%20disease,%20early-onset,%20with%20cerebral%20amyloid%20angiopathy" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Alzheimer%20disease,%20early-onset,%20with%20cerebral%20amyloid%20angiopathy%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<h3>Related information</h3>
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<div class="portlet_content DiscoveryDbLinks">
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<li class="brieflinkpopper">
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<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=400198" ref="log$=recordlinks">ClinVar</a>
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<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
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<li class="brieflinkpopper">
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<a class="brieflinkpopperctrl" href="/mesh?LinkName=medgen_mesh&from_uid=400198" ref="log$=recordlinks">MeSH</a>
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<div class="brieflinkpop offscreen_noflow">Related Medical Subject Headings</div>
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<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&from_uid=400198" ref="log$=recordlinks">OMIM</a>
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<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
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<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=400198" ref="log$=recordlinks">PMC Articles</a>
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<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
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<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=400198" ref="log$=recordlinks">PubMed</a>
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<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
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<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed_omim&from_uid=400198" ref="log$=recordlinks">PubMed (OMIM)</a>
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<h3>Recent activity</h3>
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
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Clear
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
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Turn Off
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Turn On
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<ul id="activity">
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<li class="ra_rcd ralinkpopper two_line">
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||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67cd145ef4a390645e2051e7">Alzheimer disease, early-onset, with cerebral amyloid angiopathy</a>
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<div class="ralinkpop offscreen_noflow">Alzheimer disease, early-onset, with cerebral amyloid angiopathy<div class="brieflinkpopdesc"></div></div>
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<div class="tertiary">MedGen</div>
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