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<meta name="keywords" content="C1842839, autosomal recessive localised hypotrichosis, autosomal recessive localized hypotrichosis, disease or syndrome, dsg4, dsg4 hypotrichosis, htl, hypotrichosis 6, hypotrichosis caused by mutation in dsg4, hypotrichosis type 6, hypotrichosis, localized, autosomal recessive, hypotrichosis, localized, autosomal recessive 1, hypt6, lah, lah1, localized autosomal recessive hypotrichosis, monilethrix-like hypotrichosis, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Hypotrichosis-6 (HYPT6) is a localized autosomal recessive hypotrichosis characterized by fragile hairs that break easily, leaving short, sparse scalp hairs. The disorder affects the trunk and extremities as well as the scalp, and the eyebrows and eyelashes may also be involved, whereas beard, pubic, and axillary hairs are largely spared. In addition, patients can develop hyperkeratotic follicular papules, erythema, and pruritus in affected areas. In some patients with congenital hypotrichosis, monilethrix-like hairs showing elliptical nodes have been observed (summary by Schaffer et al., 2006). Genetic Heterogeneity of Autosomal Recessive Localized Hypotrichosis LAH2 (HYPT7; 604379) is caused by mutation in the LIPH gene (607365) on chromosome 3q27, and LAH3 (HYPT8; 278150) is caused by mutation in the LPAR6 (P2RY5) gene (609239) on chromosome 13q14.12-q14.2. See also hypotrichosis and recurrent skin vesicles (613102), which is caused by mutation in the DSC3 gene (600271)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=335812
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ConceptID=C1842839
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Hypotrichosis 6<span class="h1sub">(HYPT6)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>335812</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1842839</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>HYPOTRICHOSIS, LOCALIZED, AUTOSOMAL RECESSIVE 1; HYPT6; Localized Autosomal Recessive Hypotrichosis; MONILETHRIX-LIKE HYPOTRICHOSIS</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="DSG4 - ID: 147409 - NCBI Gene" href="/gene/147409" class="medgenPMinfo">DSG4</a> (18q12.1)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0011932" target="_blank">MONDO:0011932</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/607903" target="_blank">607903</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Hypotrichosis-6 (HYPT6) is a localized autosomal recessive hypotrichosis characterized by fragile hairs that break easily, leaving short, sparse scalp hairs. The disorder affects the trunk and extremities as well as the scalp, and the eyebrows and eyelashes may also be involved, whereas beard, pubic, and axillary hairs are largely spared. In addition, patients can develop hyperkeratotic follicular papules, erythema, and pruritus in affected areas. In some patients with congenital hypotrichosis, monilethrix-like hairs showing elliptical nodes have been observed (summary by Schaffer et al., 2006). Genetic Heterogeneity of Autosomal Recessive Localized Hypotrichosis LAH2 (HYPT7; 604379) is caused by mutation in the LIPH gene (607365) on chromosome 3q27, and LAH3 (HYPT8; 278150) is caused by mutation in the LPAR6 (P2RY5) gene (609239) on chromosome 13q14.12-q14.2. See also hypotrichosis and recurrent skin vesicles (613102), which is caused by mutation in the DSC3 gene (600271). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
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<div class="portlet mgSection" id="ID_117">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Additional_description">Additional description</h1><a sid="117" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><div class="mgSection"><strong>From MedlinePlus Genetics</strong><br />Rarely, people with autosomal recessive hypotrichosis have skin problems affecting areas with sparse hair, such as redness (erythema), itchiness (pruritus), or missing patches of skin (erosions) on the scalp. In areas of poor hair growth, they may also develop bumps called hyperkeratotic follicular papules that develop around hair follicles, which are specialized structures in the skin where hair growth occurs.<br /><br />Autosomal recessive hypotrichosis is a condition that affects hair growth. People with this condition have sparse hair (hypotrichosis) on the scalp beginning in infancy. This hair is usually coarse, dry, and tightly curled (often described as woolly hair). Scalp hair may also be lighter in color than expected and is fragile and easily broken. Affected individuals often cannot grow hair longer than a few inches. The eyebrows, eyelashes, and other body hair may be sparse as well. Over time, the hair problems can remain stable or progress to complete scalp hair loss (alopecia) and a decrease in body hair. <a target="_blank" href="https://medlineplus.gov/genetics/condition/autosomal-recessive-hypotrichosis">https://medlineplus.gov/genetics/condition/autosomal-recessive-hypotrichosis</a></div></div>
|
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</div>
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||
|
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<div class="portlet mgSection" id="ID_102">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_371332"><div><strong>Sparse eyebrow</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>371332</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1832446</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Decreased density/number of eyebrow hairs.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/371332">Feature record</a> | <a href="/medgen?term=%22Sparse%20eyebrow%22%5BClinical%20Features%5D%20OR%20371332%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_19534"><div><strong>Pruritus</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>19534</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0033774</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Sign or Symptom</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased disposition to experience pruritus.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/19534">Feature record</a> | <a href="/medgen?term=%22Pruritus%22%5BClinical%20Features%5D%20OR%2019534%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_11999"><div><strong>Erythema</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>11999</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0041834</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Redness of the skin, caused by hyperemia of the capillaries in the lower layers of the skin.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/11999">Feature record</a> | <a href="/medgen?term=%22Erythema%22%5BClinical%20Features%5D%20OR%2011999%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_120480"><div><strong>Brittle hair</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120480</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0263490</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Fragile, easily breakable hair, i.e., with reduced tensile strength.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120480">Feature record</a> | <a href="/medgen?term=%22Brittle%20hair%22%5BClinical%20Features%5D%20OR%20120480%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_82670"><div><strong>Pili torti</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82670</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0263491</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pili (from Latin pilus, hair) torti (from Latin tortus, twisted) refers to short and brittle hairs that appear flattened and twisted when viewed through a microscope.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82670">Feature record</a> | <a href="/medgen?term=%22Pili%20torti%22%5BClinical%20Features%5D%20OR%2082670%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_83101"><div><strong>Phrynoderma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>83101</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0334013</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A skin condition characterized by excessive development of keratin in hair follicles, resulting in rough, cone-shaped, elevated papules resulting from closure of hair follicles with a white plug of sebum.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/83101">Feature record</a> | <a href="/medgen?term=%22Phrynoderma%22%5BClinical%20Features%5D%20OR%2083101%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_375151"><div><strong>Sparse eyelashes</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>375151</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1843300</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Decreased density/number of eyelashes.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/375151">Feature record</a> | <a href="/medgen?term=%22Sparse%20eyelashes%22%5BClinical%20Features%5D%20OR%20375151%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1790211"><div><strong>Sparse hair</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1790211</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5551005</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Reduced density of hairs.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1790211">Feature record</a> | <a href="/medgen?term=%22Sparse%20hair%22%5BClinical%20Features%5D%20OR%201790211%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of head or neck</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_371332" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Sparse eyebrow</a></span></li></ul></li><li><span class="TLline">Abnormality of the integument</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_120480" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Brittle hair</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_11999" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Erythema</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_83101" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Phrynoderma</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_82670" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pili torti</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_19534" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pruritus</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_375151" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Sparse eyelashes</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1790211" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Sparse hair</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37558233">Systematic review of mesotherapy: a novel avenue for the treatment of hair loss.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta AK,
|
||
Polla Ravi S,
|
||
Wang T,
|
||
Talukder M,
|
||
Starace M,
|
||
Piraccini BM</span><br />
|
||
<span class="medgenPMjournal">J Dermatolog Treat</span>
|
||
2023 Dec;34(1):2245084.
|
||
doi: 10.1080/09546634.2023.2245084.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37558233" target="_blank">37558233</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33940103">Treatment of pediatric alopecia areata: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barton VR,
|
||
Toussi A,
|
||
Awasthi S,
|
||
Kiuru M</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2022 Jun;86(6):1318-1334.
|
||
Epub 2021 Apr 30
|
||
doi: 10.1016/j.jaad.2021.04.077.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33940103" target="_blank">33940103</a><a href="/pmc/articles/PMC8556406" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28925637">Hair Loss: Common Causes and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Phillips TG,
|
||
Slomiany WP,
|
||
Allison R</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2017 Sep 15;96(6):371-378.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28925637" target="_blank">28925637</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(hypotrichosis%206)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (265)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36449274">Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Drake L,
|
||
Reyes-Hadsall S,
|
||
Martinez J,
|
||
Heinrich C,
|
||
Huang K,
|
||
Mostaghimi A</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2023 Jan 1;159(1):79-86.
|
||
doi: 10.1001/jamadermatol.2022.4867.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36449274" target="_blank">36449274</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34967722">Platelet-rich plasma for the treatment of alopecia: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cruciani M,
|
||
Masiello F,
|
||
Pati I,
|
||
Marano G,
|
||
Pupella S,
|
||
De Angelis V</span><br />
|
||
<span class="medgenPMjournal">Blood Transfus</span>
|
||
2023 Jan;21(1):24-36.
|
||
Epub 2021 Nov 15
|
||
doi: 10.2450/2021.0216-21.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34967722" target="_blank">34967722</a><a href="/pmc/articles/PMC9918380" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33940103">Treatment of pediatric alopecia areata: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barton VR,
|
||
Toussi A,
|
||
Awasthi S,
|
||
Kiuru M</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2022 Jun;86(6):1318-1334.
|
||
Epub 2021 Apr 30
|
||
doi: 10.1016/j.jaad.2021.04.077.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33940103" target="_blank">33940103</a><a href="/pmc/articles/PMC8556406" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32700775">Female pattern hair loss: A comprehensive review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bertoli MJ,
|
||
Sadoughifar R,
|
||
Schwartz RA,
|
||
Lotti TM,
|
||
Janniger CK</span><br />
|
||
<span class="medgenPMjournal">Dermatol Ther</span>
|
||
2020 Nov;33(6):e14055.
|
||
Epub 2020 Aug 31
|
||
doi: 10.1111/dth.14055.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32700775" target="_blank">32700775</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31578836">Italian Guidelines in diagnosis and treatment of alopecia areata.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rossi A,
|
||
Muscianese M,
|
||
Piraccini BM,
|
||
Starace M,
|
||
Carlesimo M,
|
||
Mandel VD,
|
||
Alessandrini A,
|
||
Calvieri S,
|
||
Caro G,
|
||
D'arino A,
|
||
Federico A,
|
||
Magri F,
|
||
Pigliacelli F,
|
||
Amendolagine G,
|
||
Annunziata MC,
|
||
Arisi MC,
|
||
Astorino S,
|
||
Babino G,
|
||
Bardazzi F,
|
||
Barruscotti S,
|
||
Belloni Fortina A,
|
||
Borghi A,
|
||
Bruni F,
|
||
Caccavale S,
|
||
Calzavara-Pinton P,
|
||
Cameli N,
|
||
Cardone M,
|
||
Carugno A,
|
||
Coppola R,
|
||
Dattola A,
|
||
De Felici Del Giudice MB,
|
||
Di Cesare A,
|
||
Dika E,
|
||
Di Nunno D,
|
||
D'ovidio R,
|
||
Fabbrocini G,
|
||
Feliciani C,
|
||
Fulgione E,
|
||
Galluzzo M,
|
||
Garcovich S,
|
||
Garelli V,
|
||
Guerriero C,
|
||
Hansel K,
|
||
La Placa M,
|
||
Lacarrubba F,
|
||
Lora V,
|
||
Marinello E,
|
||
Megna M,
|
||
Micali G,
|
||
Misciali C,
|
||
Monari P,
|
||
Monfrecola G,
|
||
Neri I,
|
||
Offidani A,
|
||
Orlando G,
|
||
Papini M,
|
||
Patrizi A,
|
||
Piaserico S,
|
||
Rivetti N,
|
||
Simonetti O,
|
||
Stan TR,
|
||
Stingeni L,
|
||
Talamonti M,
|
||
Tassone F,
|
||
Villa L,
|
||
Vincenzi C,
|
||
Fortuna MC</span><br />
|
||
<span class="medgenPMjournal">G Ital Dermatol Venereol</span>
|
||
2019 Dec;154(6):609-623.
|
||
Epub 2019 Sep 26
|
||
doi: 10.23736/S0392-0488.19.06458-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31578836" target="_blank">31578836</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypotrichosis%206%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1224)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38015483">Telogen effluvium: a 360 degree review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jimeno Ortega I,
|
||
Stefanato CM</span><br />
|
||
<span class="medgenPMjournal">Ital J Dermatol Venerol</span>
|
||
2023 Dec;158(6):457-466.
|
||
doi: 10.23736/S2784-8671.23.07579-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38015483" target="_blank">38015483</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37133879">Traction Alopecia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Larrondo J,
|
||
McMichael AJ</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2023 Jun 1;159(6):676.
|
||
doi: 10.1001/jamadermatol.2022.6298.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37133879" target="_blank">37133879</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34096678">Lichen planus - a clinical guide.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Solimani F,
|
||
Forchhammer S,
|
||
Schloegl A,
|
||
Ghoreschi K,
|
||
Meier K</span><br />
|
||
<span class="medgenPMjournal">J Dtsch Dermatol Ges</span>
|
||
2021 Jun;19(6):864-882.
|
||
Epub 2021 Jun 7
|
||
doi: 10.1111/ddg.14565.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34096678" target="_blank">34096678</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31578836">Italian Guidelines in diagnosis and treatment of alopecia areata.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rossi A,
|
||
Muscianese M,
|
||
Piraccini BM,
|
||
Starace M,
|
||
Carlesimo M,
|
||
Mandel VD,
|
||
Alessandrini A,
|
||
Calvieri S,
|
||
Caro G,
|
||
D'arino A,
|
||
Federico A,
|
||
Magri F,
|
||
Pigliacelli F,
|
||
Amendolagine G,
|
||
Annunziata MC,
|
||
Arisi MC,
|
||
Astorino S,
|
||
Babino G,
|
||
Bardazzi F,
|
||
Barruscotti S,
|
||
Belloni Fortina A,
|
||
Borghi A,
|
||
Bruni F,
|
||
Caccavale S,
|
||
Calzavara-Pinton P,
|
||
Cameli N,
|
||
Cardone M,
|
||
Carugno A,
|
||
Coppola R,
|
||
Dattola A,
|
||
De Felici Del Giudice MB,
|
||
Di Cesare A,
|
||
Dika E,
|
||
Di Nunno D,
|
||
D'ovidio R,
|
||
Fabbrocini G,
|
||
Feliciani C,
|
||
Fulgione E,
|
||
Galluzzo M,
|
||
Garcovich S,
|
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Garelli V,
|
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Guerriero C,
|
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Hansel K,
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La Placa M,
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Lacarrubba F,
|
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Lora V,
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Marinello E,
|
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Megna M,
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Micali G,
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Misciali C,
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Monari P,
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Monfrecola G,
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Neri I,
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Offidani A,
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Orlando G,
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Papini M,
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Patrizi A,
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Piaserico S,
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Rivetti N,
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Simonetti O,
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Stan TR,
|
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Stingeni L,
|
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Talamonti M,
|
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Tassone F,
|
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Villa L,
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Vincenzi C,
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Fortuna MC</span><br />
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<span class="medgenPMjournal">G Ital Dermatol Venereol</span>
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2019 Dec;154(6):609-623.
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Epub 2019 Sep 26
|
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doi: 10.23736/S0392-0488.19.06458-7.
|
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<span class="bold">PMID: </span><a href="/pubmed/31578836" target="_blank">31578836</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29087123">Alopecia Areata. Current situation and perspectives.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Juárez-Rendón KJ,
|
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Rivera Sánchez G,
|
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Reyes-López MÁ,
|
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García-Ortiz JE,
|
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Bocanegra-García V,
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Guardiola-Avila I,
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Altamirano-García ML</span><br />
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<span class="medgenPMjournal">Arch Argent Pediatr</span>
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2017 Dec 1;115(6):e404-e411.
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doi: 10.5546/aap.2017.eng.e404.
|
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<span class="bold">PMID: </span><a href="/pubmed/29087123" target="_blank">29087123</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypotrichosis%206%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (860)</a></div><h3 class="subhead">Therapy</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/37606849">Alopecia Areata: Current Treatments and New Directions.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Dahabreh D,
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Jung S,
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Renert-Yuval Y,
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Bar J,
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Del Duca E,
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<span class="medgenPMjournal">Am J Clin Dermatol</span>
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2023 Nov;24(6):895-912.
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Epub 2023 Aug 22
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<span class="bold">PMID: </span><a href="/pubmed/37606849" target="_blank">37606849</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34634163">Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Piraccini BM,
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Blume-Peytavi U,
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Scarci F,
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Jansat JM,
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Falqués M,
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Otero R,
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Tamarit ML,
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Galván J,
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Tebbs V,
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Massana E;
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Topical Finasteride Study Group</span><br />
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<span class="medgenPMjournal">J Eur Acad Dermatol Venereol</span>
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2022 Feb;36(2):286-294.
|
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Epub 2021 Oct 25
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doi: 10.1111/jdv.17738.
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<span class="bold">PMID: </span><a href="/pubmed/34634163" target="_blank">34634163</a><a href="/pmc/articles/PMC9297965" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/34159872">Minoxidil: a comprehensive review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gupta AK,
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Talukder M,
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Venkataraman M,
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Bamimore MA</span><br />
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<span class="medgenPMjournal">J Dermatolog Treat</span>
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2022 Jun;33(4):1896-1906.
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Epub 2021 Jul 20
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doi: 10.1080/09546634.2021.1945527.
|
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<span class="bold">PMID: </span><a href="/pubmed/34159872" target="_blank">34159872</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33940103">Treatment of pediatric alopecia areata: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barton VR,
|
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Toussi A,
|
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Awasthi S,
|
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Kiuru M</span><br />
|
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<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2022 Jun;86(6):1318-1334.
|
||
Epub 2021 Apr 30
|
||
doi: 10.1016/j.jaad.2021.04.077.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33940103" target="_blank">33940103</a><a href="/pmc/articles/PMC8556406" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25807073">5% Minoxidil: treatment for female pattern hair loss.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta AK,
|
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Foley KA</span><br />
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<span class="medgenPMjournal">Skin Therapy Lett</span>
|
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2014 Nov-Dec;19(6):5-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25807073" target="_blank">25807073</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypotrichosis%206%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1379)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36449274">Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Drake L,
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Reyes-Hadsall S,
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Martinez J,
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Heinrich C,
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Huang K,
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Mostaghimi A</span><br />
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<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2023 Jan 1;159(1):79-86.
|
||
doi: 10.1001/jamadermatol.2022.4867.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36449274" target="_blank">36449274</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34096678">Lichen planus - a clinical guide.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Solimani F,
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Forchhammer S,
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Schloegl A,
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Ghoreschi K,
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Meier K</span><br />
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<span class="medgenPMjournal">J Dtsch Dermatol Ges</span>
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2021 Jun;19(6):864-882.
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Epub 2021 Jun 7
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<span class="bold">PMID: </span><a href="/pubmed/34096678" target="_blank">34096678</a></div>
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|
||
<div class="nl"><a target="_blank" href="/pubmed/31578836">Italian Guidelines in diagnosis and treatment of alopecia areata.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Rossi A,
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Muscianese M,
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Piraccini BM,
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Starace M,
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Carlesimo M,
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Mandel VD,
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Alessandrini A,
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Calvieri S,
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Caro G,
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D'arino A,
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Federico A,
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Magri F,
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Pigliacelli F,
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Amendolagine G,
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Annunziata MC,
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Arisi MC,
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Astorino S,
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Babino G,
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Bardazzi F,
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Barruscotti S,
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Belloni Fortina A,
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Borghi A,
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Bruni F,
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Caccavale S,
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Calzavara-Pinton P,
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Cameli N,
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Cardone M,
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Carugno A,
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Coppola R,
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Dattola A,
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De Felici Del Giudice MB,
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Di Cesare A,
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Dika E,
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Di Nunno D,
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D'ovidio R,
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Fabbrocini G,
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Feliciani C,
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Fulgione E,
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Galluzzo M,
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Garcovich S,
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Garelli V,
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Guerriero C,
|
||
Hansel K,
|
||
La Placa M,
|
||
Lacarrubba F,
|
||
Lora V,
|
||
Marinello E,
|
||
Megna M,
|
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Micali G,
|
||
Misciali C,
|
||
Monari P,
|
||
Monfrecola G,
|
||
Neri I,
|
||
Offidani A,
|
||
Orlando G,
|
||
Papini M,
|
||
Patrizi A,
|
||
Piaserico S,
|
||
Rivetti N,
|
||
Simonetti O,
|
||
Stan TR,
|
||
Stingeni L,
|
||
Talamonti M,
|
||
Tassone F,
|
||
Villa L,
|
||
Vincenzi C,
|
||
Fortuna MC</span><br />
|
||
<span class="medgenPMjournal">G Ital Dermatol Venereol</span>
|
||
2019 Dec;154(6):609-623.
|
||
Epub 2019 Sep 26
|
||
doi: 10.23736/S0392-0488.19.06458-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31578836" target="_blank">31578836</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29087123">Alopecia Areata. Current situation and perspectives.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Juárez-Rendón KJ,
|
||
Rivera Sánchez G,
|
||
Reyes-López MÁ,
|
||
García-Ortiz JE,
|
||
Bocanegra-García V,
|
||
Guardiola-Avila I,
|
||
Altamirano-García ML</span><br />
|
||
<span class="medgenPMjournal">Arch Argent Pediatr</span>
|
||
2017 Dec 1;115(6):e404-e411.
|
||
doi: 10.5546/aap.2017.eng.e404.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29087123" target="_blank">29087123</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28266743">The hair follicle enigma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bernard BA</span><br />
|
||
<span class="medgenPMjournal">Exp Dermatol</span>
|
||
2017 Jun;26(6):472-477.
|
||
Epub 2017 May 9
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||
doi: 10.1111/exd.13337.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28266743" target="_blank">28266743</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypotrichosis%206%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (531)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37558233">Systematic review of mesotherapy: a novel avenue for the treatment of hair loss.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta AK,
|
||
Polla Ravi S,
|
||
Wang T,
|
||
Talukder M,
|
||
Starace M,
|
||
Piraccini BM</span><br />
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||
<span class="medgenPMjournal">J Dermatolog Treat</span>
|
||
2023 Dec;34(1):2245084.
|
||
doi: 10.1080/09546634.2023.2245084.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37558233" target="_blank">37558233</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37062298">Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b-3 trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">King B,
|
||
Zhang X,
|
||
Harcha WG,
|
||
Szepietowski JC,
|
||
Shapiro J,
|
||
Lynde C,
|
||
Mesinkovska NA,
|
||
Zwillich SH,
|
||
Napatalung L,
|
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Wajsbrot D,
|
||
Fayyad R,
|
||
Freyman A,
|
||
Mitra D,
|
||
Purohit V,
|
||
Sinclair R,
|
||
Wolk R</span><br />
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<span class="medgenPMjournal">Lancet</span>
|
||
2023 May 6;401(10387):1518-1529.
|
||
Epub 2023 Apr 14
|
||
doi: 10.1016/S0140-6736(23)00222-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37062298" target="_blank">37062298</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36877879">Reversal of Stress-Associated Alopecia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kalner S,
|
||
Vergilis I</span><br />
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<span class="medgenPMjournal">J Drugs Dermatol</span>
|
||
2023 Mar 1;22(3):300-301.
|
||
doi: 10.36849/JDD.7161.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36877879" target="_blank">36877879</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34634163">Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Piraccini BM,
|
||
Blume-Peytavi U,
|
||
Scarci F,
|
||
Jansat JM,
|
||
Falqués M,
|
||
Otero R,
|
||
Tamarit ML,
|
||
Galván J,
|
||
Tebbs V,
|
||
Massana E;
|
||
Topical Finasteride Study Group</span><br />
|
||
<span class="medgenPMjournal">J Eur Acad Dermatol Venereol</span>
|
||
2022 Feb;36(2):286-294.
|
||
Epub 2021 Oct 25
|
||
doi: 10.1111/jdv.17738.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34634163" target="_blank">34634163</a><a href="/pmc/articles/PMC9297965" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25807073">5% Minoxidil: treatment for female pattern hair loss.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta AK,
|
||
Foley KA</span><br />
|
||
<span class="medgenPMjournal">Skin Therapy Lett</span>
|
||
2014 Nov-Dec;19(6):5-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25807073" target="_blank">25807073</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypotrichosis%206%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (836)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37558233">Systematic review of mesotherapy: a novel avenue for the treatment of hair loss.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta AK,
|
||
Polla Ravi S,
|
||
Wang T,
|
||
Talukder M,
|
||
Starace M,
|
||
Piraccini BM</span><br />
|
||
<span class="medgenPMjournal">J Dermatolog Treat</span>
|
||
2023 Dec;34(1):2245084.
|
||
doi: 10.1080/09546634.2023.2245084.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37558233" target="_blank">37558233</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36980291">Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krefft-Trzciniecka K,
|
||
Piętowska Z,
|
||
Nowicka D,
|
||
Szepietowski JC</span><br />
|
||
<span class="medgenPMjournal">Cells</span>
|
||
2023 Mar 21;12(6)
|
||
doi: 10.3390/cells12060951.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36980291" target="_blank">36980291</a><a href="/pmc/articles/PMC10047891" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36449274">Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Drake L,
|
||
Reyes-Hadsall S,
|
||
Martinez J,
|
||
Heinrich C,
|
||
Huang K,
|
||
Mostaghimi A</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2023 Jan 1;159(1):79-86.
|
||
doi: 10.1001/jamadermatol.2022.4867.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36449274" target="_blank">36449274</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34967722">Platelet-rich plasma for the treatment of alopecia: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cruciani M,
|
||
Masiello F,
|
||
Pati I,
|
||
Marano G,
|
||
Pupella S,
|
||
De Angelis V</span><br />
|
||
<span class="medgenPMjournal">Blood Transfus</span>
|
||
2023 Jan;21(1):24-36.
|
||
Epub 2021 Nov 15
|
||
doi: 10.2450/2021.0216-21.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34967722" target="_blank">34967722</a><a href="/pmc/articles/PMC9918380" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33940103">Treatment of pediatric alopecia areata: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barton VR,
|
||
Toussi A,
|
||
Awasthi S,
|
||
Kiuru M</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2022 Jun;86(6):1318-1334.
|
||
Epub 2021 Apr 30
|
||
doi: 10.1016/j.jaad.2021.04.077.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33940103" target="_blank">33940103</a><a href="/pmc/articles/PMC8556406" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypotrichosis%206%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (79)</a></div></div>
|
||
</div>
|
||
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|
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</div>
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</div>
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</div>
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<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
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|
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<!-- MedGen supplemental column starts here -->
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<div class="rightCol mgCol">
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul id="my-toc"></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1842839%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (10)</a></li>
|
||
<li><a href="/gtr/tests?term=C1842839%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (14)</a></li>
|
||
<li><a href="/gtr/tests?term=C1842839%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (4)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C1842839%5bDISCUI%5d" target="_blank">See all (15)</a></total></li>
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</ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=607903" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Hypotrichosis%206" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(hypotrichosis%206)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=607892" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=147409[geneid]" target="_blank">View DSG4 variations in ClinVar</a></li><li><a href="/nuccore/260656011" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=607903" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
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<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=335812" ref="log$=recordlinks">ClinVar</a>
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