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<meta name="keywords" content="C0271616, disease or syndrome, female organism precocious puberty, precocious female puberty, precocious puberty in female, precocious puberty in females, precocious puberty of female organism, precocious puberty, females, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="The onset of puberty before the age of 8 years in girls." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=543449
|
||
ConceptID=C0271616
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Precocious puberty in females</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>543449</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0271616</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Precocious puberty, females</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Precocious female puberty (19911007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0010465">HP:0010465</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0018561" target="_blank">MONDO:0018561</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=435561">ORPHA435561</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">The onset of puberty before the age of 8 years in girls. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Precocious puberty in females</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/893021" ref="tree=MeSH" title="MedGen record for Abnormality of the endocrine system">Abnormality of the endocrine system</a></span><ul><li><span class="TLline"><a href="/medgen/870247" ref="tree=MeSH" title="MedGen record for Puberty and gonadal disorders">Puberty and gonadal disorders</a></span><ul><li><span class="TLline"><a href="/medgen/868001" ref="tree=MeSH" title="MedGen record for Early onset of sexual maturation">Early onset of sexual maturation</a></span><ul><li><span class="TLline"><a href="/medgen/18752" ref="tree=MeSH" title="MedGen record for Precocious puberty">Precocious puberty</a></span><ul><li><span class="matched_ds">Precocious puberty in females</span><ul><li><span class="TLline"><a href="/medgen/409989" ref="tree=MeSH" title="MedGen record for Aromatase excess syndrome">Aromatase excess syndrome</a></span></li><li><span class="TLline"><a href="/medgen/90985" ref="tree=MeSH" title="MedGen record for Central precocious puberty">Central precocious puberty</a></span><ul><li><span class="TLline"><a href="/medgen/575094" ref="tree=MeSH" title="MedGen record for Idiopathic central precocious puberty">Idiopathic central precocious puberty</a></span></li><li><span class="TLline"><a href="/medgen/797791" ref="tree=MeSH" title="MedGen record for Secondary central precocious puberty">Secondary central precocious puberty</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/69164" ref="tree=MeSH" title="MedGen record for McCune-Albright syndrome">McCune-Albright syndrome</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_1808571"><div><strong>Intellectual developmental disorder, autosomal recessive 76</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1808571</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5677007</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Mental or Behavioral Dysfunction</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal recessive intellectual developmental disorder-76 (MRT76) is characterized by impaired intellectual development, absent speech, poor sleep, abnormal EEG with seizures, normal brain imaging, and precocious puberty (Ismail et al., 2022).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1808571">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1841035"><div><strong>Premature ovarian failure 21</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1841035</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5830399</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Premature ovarian failure-21 (POF21) is characterized by female infertility due to primary or secondary amenorrhea. Ovaries are small, atrophic, or nonvisualized on ultrasound (Tucker et al., 2019; Tucker et al., 2022). For a general phenotypic description and a discussion of genetic heterogeneity of POF, see POF1 (311360).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1841035">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1808571" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual developmental disorder, autosomal recessive 76</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1841035" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Premature ovarian failure 21</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30086862">Central precocious puberty: From genetics to treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aguirre RS,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Endocrinol Metab</span>
|
||
2018 Aug;32(4):343-354.
|
||
Epub 2018 May 26
|
||
doi: 10.1016/j.beem.2018.05.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30086862" target="_blank">30086862</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26852255">Causes, diagnosis, and treatment of central precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Latronico AC,
|
||
Brito VN,
|
||
Carel JC</span><br />
|
||
<span class="medgenPMjournal">Lancet Diabetes Endocrinol</span>
|
||
2016 Mar;4(3):265-274.
|
||
Epub 2016 Feb 4
|
||
doi: 10.1016/S2213-8587(15)00380-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26852255" target="_blank">26852255</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(precocious%20puberty%20in%20females)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (310)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36916130">Approach to the Patient: Central Precocious Puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kilberg MJ,
|
||
Vogiatzi MG</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2023 Jul 14;108(8):2115-2123.
|
||
doi: 10.1210/clinem/dgad081.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36916130" target="_blank">36916130</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33788946">Normal and Premature Adrenarche.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rosenfield RL</span><br />
|
||
<span class="medgenPMjournal">Endocr Rev</span>
|
||
2021 Nov 16;42(6):783-814.
|
||
doi: 10.1210/endrev/bnab009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33788946" target="_blank">33788946</a><a href="/pmc/articles/PMC8599200" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32482957">Pubertal Development: What's Normal/What's Not.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Smith CE,
|
||
Biro FM</span><br />
|
||
<span class="medgenPMjournal">Clin Obstet Gynecol</span>
|
||
2020 Sep;63(3):491-503.
|
||
doi: 10.1097/GRF.0000000000000537.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32482957" target="_blank">32482957</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19332438">Consensus statement on the use of gonadotropin-releasing hormone analogs in children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Carel JC,
|
||
Eugster EA,
|
||
Rogol A,
|
||
Ghizzoni L,
|
||
Palmert MR;
|
||
ESPE-LWPES GnRH Analogs Consensus Conference Group,
|
||
Antoniazzi F,
|
||
Berenbaum S,
|
||
Bourguignon JP,
|
||
Chrousos GP,
|
||
Coste J,
|
||
Deal S,
|
||
de Vries L,
|
||
Foster C,
|
||
Heger S,
|
||
Holland J,
|
||
Jahnukainen K,
|
||
Juul A,
|
||
Kaplowitz P,
|
||
Lahlou N,
|
||
Lee MM,
|
||
Lee P,
|
||
Merke DP,
|
||
Neely EK,
|
||
Oostdijk W,
|
||
Phillip M,
|
||
Rosenfield RL,
|
||
Shulman D,
|
||
Styne D,
|
||
Tauber M,
|
||
Wit JM</span><br />
|
||
<span class="medgenPMjournal">Pediatrics</span>
|
||
2009 Apr;123(4):e752-62.
|
||
Epub 2009 Mar 30
|
||
doi: 10.1542/peds.2008-1783.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19332438" target="_blank">19332438</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Precocious%20puberty%20in%20females%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1500)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37074536">Precocious Puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Banerjee S,
|
||
Bajpai A</span><br />
|
||
<span class="medgenPMjournal">Indian J Pediatr</span>
|
||
2023 Jun;90(6):582-589.
|
||
Epub 2023 Apr 19
|
||
doi: 10.1007/s12098-023-04554-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37074536" target="_blank">37074536</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32748611">Precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gangat M,
|
||
Radovick S</span><br />
|
||
<span class="medgenPMjournal">Minerva Pediatr</span>
|
||
2020 Dec;72(6):491-500.
|
||
Epub 2020 Aug 4
|
||
doi: 10.23736/S0026-4946.20.05970-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32748611" target="_blank">32748611</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26133309">Precocious Puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Long D</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
2015 Jul;36(7):319-21.
|
||
doi: 10.1542/pir.36-7-319.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26133309" target="_blank">26133309</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18509122">Clinical practice. Precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Carel JC,
|
||
Léger J</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2008 May 29;358(22):2366-77.
|
||
doi: 10.1056/NEJMcp0800459.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18509122" target="_blank">18509122</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Precocious%20puberty%20in%20females%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1664)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37074536">Precocious Puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Banerjee S,
|
||
Bajpai A</span><br />
|
||
<span class="medgenPMjournal">Indian J Pediatr</span>
|
||
2023 Jun;90(6):582-589.
|
||
Epub 2023 Apr 19
|
||
doi: 10.1007/s12098-023-04554-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37074536" target="_blank">37074536</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31319416">Use of Gonadotropin-Releasing Hormone Analogs in Children: Update by an International Consortium.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bangalore Krishna K,
|
||
Fuqua JS,
|
||
Rogol AD,
|
||
Klein KO,
|
||
Popovic J,
|
||
Houk CP,
|
||
Charmandari E,
|
||
Lee PA,
|
||
Freire AV,
|
||
Ropelato MG,
|
||
Yazid Jalaludin M,
|
||
Mbogo J,
|
||
Kanaka-Gantenbein C,
|
||
Luo X,
|
||
Eugster EA,
|
||
Klein KO,
|
||
Vogiatzi MG,
|
||
Reifschneider K,
|
||
Bamba V,
|
||
Garcia Rudaz C,
|
||
Kaplowitz P,
|
||
Backeljauw P,
|
||
Allen DB,
|
||
Palmert MR,
|
||
Harrington J,
|
||
Guerra-Junior G,
|
||
Stanley T,
|
||
Torres Tamayo M,
|
||
Miranda Lora AL,
|
||
Bajpai A,
|
||
Silverman LA,
|
||
Miller BS,
|
||
Dayal A,
|
||
Horikawa R,
|
||
Oberfield S,
|
||
Rogol AD,
|
||
Tajima T,
|
||
Popovic J,
|
||
Witchel SF,
|
||
Rosenthal SM,
|
||
Finlayson C,
|
||
Hannema SE,
|
||
Castilla-Peon MF,
|
||
Mericq V,
|
||
Medina Bravo PG</span><br />
|
||
<span class="medgenPMjournal">Horm Res Paediatr</span>
|
||
2019;91(6):357-372.
|
||
Epub 2019 Jul 18
|
||
doi: 10.1159/000501336.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31319416" target="_blank">31319416</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25144596">Precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Neely EK,
|
||
Crossen SS</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Obstet Gynecol</span>
|
||
2014 Oct;26(5):332-8.
|
||
doi: 10.1097/GCO.0000000000000099.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25144596" target="_blank">25144596</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18698101">Precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karthikeyan A</span><br />
|
||
<span class="medgenPMjournal">Clin Pediatr (Phila)</span>
|
||
2008 Sep;47(7):718.
|
||
doi: 10.1177/0009922808315220.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18698101" target="_blank">18698101</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Precocious%20puberty%20in%20females%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1135)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36339428">Precocious puberty and microbiota: The role of the sex hormone-gut microbiome axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Calcaterra V,
|
||
Rossi V,
|
||
Massini G,
|
||
Regalbuto C,
|
||
Hruby C,
|
||
Panelli S,
|
||
Bandi C,
|
||
Zuccotti G</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2022;13:1000919.
|
||
Epub 2022 Oct 21
|
||
doi: 10.3389/fendo.2022.1000919.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36339428" target="_blank">36339428</a><a href="/pmc/articles/PMC9634744" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29323691">Premature Thelarche.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khokhar A,
|
||
Mojica A</span><br />
|
||
<span class="medgenPMjournal">Pediatr Ann</span>
|
||
2018 Jan 1;47(1):e12-e15.
|
||
doi: 10.3928/19382359-20171214-01.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29323691" target="_blank">29323691</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25144596">Precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Neely EK,
|
||
Crossen SS</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Obstet Gynecol</span>
|
||
2014 Oct;26(5):332-8.
|
||
doi: 10.1097/GCO.0000000000000099.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25144596" target="_blank">25144596</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17012487">Precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muir A</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
2006 Oct;27(10):373-81.
|
||
doi: 10.1542/pir.27-10-373.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17012487" target="_blank">17012487</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16798284">Nonclassic adrenal hyperplasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moran C</span><br />
|
||
<span class="medgenPMjournal">Fertil Steril</span>
|
||
2006 Jul;86 Suppl 1:S3.
|
||
doi: 10.1016/j.fertnstert.2006.03.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16798284" target="_blank">16798284</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Precocious%20puberty%20in%20females%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (858)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37496240">Premature Thelarche: An Updated Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leung AKC,
|
||
Lam JM,
|
||
Hon KL</span><br />
|
||
<span class="medgenPMjournal">Curr Pediatr Rev</span>
|
||
2024;20(4):500-509.
|
||
doi: 10.2174/1573396320666230726110658.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37496240" target="_blank">37496240</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36339428">Precocious puberty and microbiota: The role of the sex hormone-gut microbiome axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Calcaterra V,
|
||
Rossi V,
|
||
Massini G,
|
||
Regalbuto C,
|
||
Hruby C,
|
||
Panelli S,
|
||
Bandi C,
|
||
Zuccotti G</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2022;13:1000919.
|
||
Epub 2022 Oct 21
|
||
doi: 10.3389/fendo.2022.1000919.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36339428" target="_blank">36339428</a><a href="/pmc/articles/PMC9634744" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34784914">Obesity is a risk factor for central precocious puberty: a case-control study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu G,
|
||
Guo J,
|
||
Zhang X,
|
||
Lu Y,
|
||
Miao J,
|
||
Xue H</span><br />
|
||
<span class="medgenPMjournal">BMC Pediatr</span>
|
||
2021 Nov 16;21(1):509.
|
||
doi: 10.1186/s12887-021-02936-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34784914" target="_blank">34784914</a><a href="/pmc/articles/PMC8594221" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32591066">Update on Precocious Puberty: Who Should Be Treated?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kaplowitz PB</span><br />
|
||
<span class="medgenPMjournal">Adv Pediatr</span>
|
||
2020 Aug;67:93-104.
|
||
Epub 2020 May 26
|
||
doi: 10.1016/j.yapd.2020.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32591066" target="_blank">32591066</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29323690">Premature Adrenarche.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Novello L,
|
||
Speiser PW</span><br />
|
||
<span class="medgenPMjournal">Pediatr Ann</span>
|
||
2018 Jan 1;47(1):e7-e11.
|
||
doi: 10.3928/19382359-20171214-04.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29323690" target="_blank">29323690</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Precocious%20puberty%20in%20females%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1044)</a></div></div>
|
||
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|
||
|
||
<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38116317">An updated meta-analysis of the relationship between vitamin D levels and precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cheng H,
|
||
Chen D,
|
||
Gao H</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2023;14:1298374.
|
||
Epub 2023 Dec 5
|
||
doi: 10.3389/fendo.2023.1298374.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38116317" target="_blank">38116317</a><a href="/pmc/articles/PMC10728595" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37848909">Lipid profile in girls with precocious puberty: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jiang M,
|
||
Gao Y,
|
||
Wang K,
|
||
Huang L</span><br />
|
||
<span class="medgenPMjournal">BMC Endocr Disord</span>
|
||
2023 Oct 18;23(1):225.
|
||
doi: 10.1186/s12902-023-01470-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37848909" target="_blank">37848909</a><a href="/pmc/articles/PMC10583444" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36501034">Diet and Nutrients Intakes during Infancy and Childhood in Relation to Early Puberty: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tang J,
|
||
Xue P,
|
||
Huang X,
|
||
Lin C,
|
||
Liu S</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2022 Nov 24;14(23)
|
||
doi: 10.3390/nu14235004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36501034" target="_blank">36501034</a><a href="/pmc/articles/PMC9739867" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33887744">Kisspeptin Levels in Girls with Precocious Puberty: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cintra RG,
|
||
Wajnsztejn R,
|
||
Trevisan CM,
|
||
Zaia V,
|
||
Laganà AS,
|
||
Bianco B,
|
||
Montagna E</span><br />
|
||
<span class="medgenPMjournal">Horm Res Paediatr</span>
|
||
2020;93(11-12):589-598.
|
||
Epub 2021 Apr 22
|
||
doi: 10.1159/000515660.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33887744" target="_blank">33887744</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32040143">Worldwide Secular Trends in Age at Pubertal Onset Assessed by Breast Development Among Girls: A Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Eckert-Lind C,
|
||
Busch AS,
|
||
Petersen JH,
|
||
Biro FM,
|
||
Butler G,
|
||
Bräuner EV,
|
||
Juul A</span><br />
|
||
<span class="medgenPMjournal">JAMA Pediatr</span>
|
||
2020 Apr 1;174(4):e195881.
|
||
Epub 2020 Apr 6
|
||
doi: 10.1001/jamapediatrics.2019.5881.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32040143" target="_blank">32040143</a><a href="/pmc/articles/PMC7042934" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Precocious%20puberty%20in%20females%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (28)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(precocious%20puberty%20in%20females)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Precocious%20puberty%20in%20females%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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