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<meta name="keywords" content="C0206061, disease or syndrome, interstitial pneumonia, interstitial pneumonias, interstitial pneumonitides, interstitial pneumonitis, pneumonia, interstitial, pneumonias, interstitial, pneumonitides, interstitial, pneumonitis, interstitial, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Inflammation of interstitial lung tissue, usually associated with infection." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=61507
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ConceptID=C0206061
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Interstitial pneumonitis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>61507</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0206061</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Interstitial Pneumonia; Interstitial Pneumonias; Interstitial Pneumonitides; Interstitial Pneumonitis; Pneumonia, Interstitial; Pneumonias, Interstitial; Pneumonitides, Interstitial; Pneumonitis, Interstitial</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Interstitial pneumonia (64667001)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0006515">HP:0006515</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Inflammation of interstitial lung tissue, usually associated with infection. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Interstitial pneumonitis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/866322" ref="tree=MeSH" title="MedGen record for Abnormality of the respiratory system">Abnormality of the respiratory system</a></span><ul><li><span class="TLline"><a href="/medgen/220360" ref="tree=MeSH" title="MedGen record for Abnormal respiratory system physiology">Abnormal respiratory system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/868593" ref="tree=MeSH" title="MedGen record for Abnormal respiratory system morphology">Abnormal respiratory system morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892303" ref="tree=MeSH" title="MedGen record for Abnormality of the lung">Abnormality of the lung</a></span><ul><li><span class="TLline"><a href="/medgen/1788738" ref="tree=MeSH" title="MedGen record for Abnormal pulmonary interstitial morphology">Abnormal pulmonary interstitial morphology</a></span><ul><li><span class="matched_ds">Interstitial pneumonitis</span><ul><li><span class="TLline"><a href="/medgen/389939" ref="tree=MeSH" title="MedGen record for Idiopathic interstitial pneumonia">Idiopathic interstitial pneumonia</a></span><ul><li><span class="TLline"><a href="/medgen/39340" ref="tree=MeSH" title="MedGen record for Acute interstitial pneumonia">Acute interstitial pneumonia</a></span></li><li><span class="TLline"><a href="/medgen/116663" ref="tree=MeSH" title="MedGen record for Bronchiolitis obliterans organizing pneumonia">Bronchiolitis obliterans organizing pneumonia</a></span></li><li><span class="TLline"><a href="/medgen/838971" ref="tree=MeSH" title="MedGen record for Combined pulmonary fibrosis-emphysema syndrome">Combined pulmonary fibrosis-emphysema syndrome</a></span></li><li><span class="TLline"><a href="/medgen/65962" ref="tree=MeSH" title="MedGen record for Desquamative interstitial pneumonia">Desquamative interstitial pneumonia</a></span></li><li><span class="TLline"><a href="/medgen/1798890" ref="tree=MeSH" title="MedGen record for Idiopathic pleuroparenchymal fibroelastosis">Idiopathic pleuroparenchymal fibroelastosis</a></span></li><li><span class="TLline"><a href="/medgen/321462" ref="tree=MeSH" title="MedGen record for Idiopathic Pulmonary Fibrosis">Idiopathic Pulmonary Fibrosis</a></span></li><li><span class="TLline"><a href="/medgen/1794136" ref="tree=MeSH" title="MedGen record for Interstitial lung disease 2">Interstitial lung disease 2</a></span></li><li><span class="TLline"><a href="/medgen/82682" ref="tree=MeSH" title="MedGen record for Lymphocytic interstitial pneumonia">Lymphocytic interstitial pneumonia</a></span></li><li><span class="TLline"><a href="/medgen/220936" ref="tree=MeSH" title="MedGen record for Non-specific interstitial pneumonia">Non-specific interstitial pneumonia</a></span><ul><li><span class="TLline"><a href="/medgen/1782036" ref="tree=MeSH" title="MedGen record for Cellular non-specific interstitial pneumonia">Cellular non-specific interstitial pneumonia</a></span></li><li><span class="TLline"><a href="/medgen/1786141" ref="tree=MeSH" title="MedGen record for Fibrotic non-specific interstitial pneumonia">Fibrotic non-specific interstitial pneumonia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1672485" ref="tree=MeSH" title="MedGen record for Respiratory bronchiolitis-interstitial lung disease syndrome">Respiratory bronchiolitis-interstitial lung disease syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1662563" ref="tree=MeSH" title="MedGen record for Usual interstitial pneumonia">Usual interstitial pneumonia</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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||
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||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_410078"><div><strong>Surfactant metabolism dysfunction, pulmonary, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>410078</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1970470</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pulmonary surfactant metabolism dysfunction-2 (SMDP2) is a rare autosomal dominant disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course. The pathophysiology of the disorder is postulated to involve intracellular accumulation of a structurally defective SPC protein (Thomas et al., 2002). For a general phenotypic description and a discussion of genetic heterogeneity of pulmonary surfactant metabolism dysfunction, see SMDP1 (265120).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/410078">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_766875"><div><strong>Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>766875</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3553961</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autoinflammation, antibody deficiency, and immune dysregulation (APLAID) is an autosomal dominant systemic disorder characterized by recurrent blistering skin lesions with a dense inflammatory infiltrate and variable involvement of other tissues, including joints, the eye, and the gastrointestinal tract. Affected individuals have a mild humoral immune deficiency associated with recurrent sinopulmonary infections, but no evidence of circulating autoantibodies (summary by Zhou et al., 2012).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/766875">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_863232"><div><strong>STAT3-related early-onset multisystem autoimmune disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>863232</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4014795</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Infantile-onset multisystem autoimmune disease-1 is characterized by early childhood onset of a spectrum of autoimmune disorders affecting multiple organs. Common manifestations include insulin-dependent diabetes mellitus and autoimmune enteropathy, or celiac disease, and autoimmune hematologic disorders. Other features include short stature and nonspecific dermatitis. More variable features include hypothyroidism, autoimmune arthritis, and delayed puberty. Some patients may show recurrent infections. The disorder results from an inborn error of cytokine signaling (summary by Flanagan et al., 2014 and Milner et al., 2015). Genetic Heterogeneity of Infantile-Onset Multisystem Autoimmune Disease See also ADMIO2 (617006), caused by mutation in the ZAP70 gene (176947) on chromosome 2q12, and ADMIO3 (620430), caused by mutation in the CBLB gene (604491) on chromosome 3q13.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/863232">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_901370"><div><strong>DOCK2 deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>901370</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4225328</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-40 is an autosomal recessive primary form of combined immunodeficiency mainly affecting T-cell number and function, with other more variable defects in B-cell and NK-cell function. Patients have onset of severe invasive bacterial and viral infections in early childhood and may die without bone marrow transplantation (summary by Dobbs et al., 2015).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/901370">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1645250"><div><strong>Dyskeratosis congenita, autosomal dominant 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1645250</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551974</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Dyskeratosis congenita and related telomere biology disorders (DC/TBD) are caused by impaired telomere maintenance resulting in short or very short telomeres. The phenotypic spectrum of telomere biology disorders is broad and includes individuals with classic dyskeratosis congenita (DC) as well as those with very short telomeres and an isolated physical finding. Classic DC is characterized by a triad of dysplastic nails, lacy reticular pigmentation of the upper chest and/or neck, and oral leukoplakia, although this may not be present in all individuals. People with DC/TBD are at increased risk for progressive bone marrow failure (BMF), myelodysplastic syndrome or acute myelogenous leukemia, solid tumors (usually squamous cell carcinoma of the head/neck or anogenital cancer), and pulmonary fibrosis. Other findings can include eye abnormalities (epiphora, blepharitis, sparse eyelashes, ectropion, entropion, trichiasis), taurodontism, liver disease, gastrointestinal telangiectasias, and avascular necrosis of the hips or shoulders. Although most persons with DC/TBD have normal psychomotor development and normal neurologic function, significant developmental delay is present in both forms; additional findings include cerebellar hypoplasia (Hoyeraal Hreidarsson syndrome) and bilateral exudative retinopathy and intracranial calcifications (Revesz syndrome and Coats plus syndrome). Onset and progression of manifestations of DC/TBD vary: at the mild end of the spectrum are those who have only minimal physical findings with normal bone marrow function, and at the severe end are those who have the diagnostic triad and early-onset BMF.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1645250">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1841007"><div><strong>Autoinflammation with pulmonary and cutaneous vasculitis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1841007</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5830371</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autoinflammation with pulmonary and cutaneous vasculitis (AIPCV) is a disorder of immune dysregulation manifest as skin lesions (petechiae and purpura) appearing soon after birth followed by progressive pulmonary involvement causing restrictive lung disease and respiratory insufficiency. Other features may include hepatosplenomegaly and anemia (Kanderova et al., 2022).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1841007">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1841007" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autoinflammation with pulmonary and cutaneous vasculitis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_766875" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_901370" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">DOCK2 deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1645250" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Dyskeratosis congenita, autosomal dominant 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_863232" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">STAT3-related early-onset multisystem autoimmune disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_410078" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Surfactant metabolism dysfunction, pulmonary, 2</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31762218">Clinical diagnosis and treatment of immune checkpoint inhibitor-associated pneumonitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang H,
|
||
Guo X,
|
||
Zhou J,
|
||
Li Y,
|
||
Duan L,
|
||
Si X,
|
||
Zhang L,
|
||
Liu X,
|
||
Wang M,
|
||
Shi J,
|
||
Zhang L</span><br />
|
||
<span class="medgenPMjournal">Thorac Cancer</span>
|
||
2020 Jan;11(1):191-197.
|
||
Epub 2019 Nov 24
|
||
doi: 10.1111/1759-7714.13240.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31762218" target="_blank">31762218</a><a href="/pmc/articles/PMC6938759" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28087540">International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fajgenbaum DC,
|
||
Uldrick TS,
|
||
Bagg A,
|
||
Frank D,
|
||
Wu D,
|
||
Srkalovic G,
|
||
Simpson D,
|
||
Liu AY,
|
||
Menke D,
|
||
Chandrakasan S,
|
||
Lechowicz MJ,
|
||
Wong RS,
|
||
Pierson S,
|
||
Paessler M,
|
||
Rossi JF,
|
||
Ide M,
|
||
Ruth J,
|
||
Croglio M,
|
||
Suarez A,
|
||
Krymskaya V,
|
||
Chadburn A,
|
||
Colleoni G,
|
||
Nasta S,
|
||
Jayanthan R,
|
||
Nabel CS,
|
||
Casper C,
|
||
Dispenzieri A,
|
||
Fosså A,
|
||
Kelleher D,
|
||
Kurzrock R,
|
||
Voorhees P,
|
||
Dogan A,
|
||
Yoshizaki K,
|
||
van Rhee F,
|
||
Oksenhendler E,
|
||
Jaffe ES,
|
||
Elenitoba-Johnson KS,
|
||
Lim MS</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2017 Mar 23;129(12):1646-1657.
|
||
Epub 2017 Jan 13
|
||
doi: 10.1182/blood-2016-10-746933.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28087540" target="_blank">28087540</a><a href="/pmc/articles/PMC5364342" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4456978">Chronic interstitial pneumonitis with fibrosis during long-term treatment with nitrofurantoin.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Strandberg I,
|
||
Wengle B,
|
||
Fagrell B</span><br />
|
||
<span class="medgenPMjournal">Acta Med Scand</span>
|
||
1974 Dec;196(6):483-7.
|
||
doi: 10.1111/j.0954-6820.1974.tb01046.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4456978" target="_blank">4456978</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22interstitial%20pneumonitis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (74)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38723554">MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">David P,
|
||
Sinha S,
|
||
Iqbal K,
|
||
De Marco G,
|
||
Taheri S,
|
||
McLaren E,
|
||
Maisuria S,
|
||
Arumugakani G,
|
||
Ash Z,
|
||
Buckley C,
|
||
Coles L,
|
||
Hettiarachchi C,
|
||
Payne E,
|
||
Savic S,
|
||
Smithson G,
|
||
Slade M,
|
||
Shah R,
|
||
Marzo-Ortega H,
|
||
Keen M,
|
||
Lawson C,
|
||
Mclorinan J,
|
||
Nizam S,
|
||
Reddy H,
|
||
Sharif O,
|
||
Sultan S,
|
||
Tran G,
|
||
Wood M,
|
||
Wood S,
|
||
Ghosh P,
|
||
McGonagle D</span><br />
|
||
<span class="medgenPMjournal">EBioMedicine</span>
|
||
2024 Jun;104:105136.
|
||
Epub 2024 May 8
|
||
doi: 10.1016/j.ebiom.2024.105136.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38723554" target="_blank">38723554</a><a href="/pmc/articles/PMC11090026" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36600276">Interstitial pneumonitis associated with combined regimen of immunotherapy and conventional therapies-pharmacovigilance database analysis with real-world data validation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Guo XJ,
|
||
Cai XT,
|
||
Rong ZX,
|
||
Zhang YP,
|
||
Wen YX,
|
||
Bai X,
|
||
Wang J,
|
||
Fu QJ,
|
||
Guo ZQ,
|
||
Long LL,
|
||
Ma SC,
|
||
Tang XR,
|
||
Liu L,
|
||
Guan J,
|
||
Dong ZY,
|
||
Wu DH</span><br />
|
||
<span class="medgenPMjournal">BMC Med</span>
|
||
2023 Jan 5;21(1):6.
|
||
doi: 10.1186/s12916-022-02713-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36600276" target="_blank">36600276</a><a href="/pmc/articles/PMC9814324" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32379511">Smoking-associated interstitial lung disease: update and review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dawod YT,
|
||
Cook NE,
|
||
Graham WB,
|
||
Madhani-Lovely F,
|
||
Thao C</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Respir Med</span>
|
||
2020 Aug;14(8):825-834.
|
||
Epub 2020 May 22
|
||
doi: 10.1080/17476348.2020.1766971.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32379511" target="_blank">32379511</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11129733">Irinotecan-associated pulmonary toxicity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Madarnas Y,
|
||
Webster P,
|
||
Shorter AM,
|
||
Bjarnason GA</span><br />
|
||
<span class="medgenPMjournal">Anticancer Drugs</span>
|
||
2000 Oct;11(9):709-13.
|
||
doi: 10.1097/00001813-200010000-00007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11129733" target="_blank">11129733</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1691067">Bleomycin-induced pulmonary toxicity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jules-Elysee K,
|
||
White DA</span><br />
|
||
<span class="medgenPMjournal">Clin Chest Med</span>
|
||
1990 Mar;11(1):1-20.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1691067" target="_blank">1691067</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Interstitial%20pneumonitis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (656)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37850435">COVID-19? Let me see your hands.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bernal-Bello D,
|
||
Lara-Montes C,
|
||
Jaenes-Barrios B</span><br />
|
||
<span class="medgenPMjournal">J R Coll Physicians Edinb</span>
|
||
2023 Dec;53(4):269-271.
|
||
Epub 2023 Oct 18
|
||
doi: 10.1177/14782715231206530.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37850435" target="_blank">37850435</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31299851">DRESS Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jain P,
|
||
Garg S,
|
||
Sharma VK,
|
||
Maheshwari S</span><br />
|
||
<span class="medgenPMjournal">J Assoc Physicians India</span>
|
||
2019 Apr;67(4):87-88.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31299851" target="_blank">31299851</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31227290">An update on IgG4-related lung disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morales AT,
|
||
Cignarella AG,
|
||
Jabeen IS,
|
||
Barkin JS,
|
||
Mirsaeidi M</span><br />
|
||
<span class="medgenPMjournal">Eur J Intern Med</span>
|
||
2019 Aug;66:18-24.
|
||
Epub 2019 Jun 19
|
||
doi: 10.1016/j.ejim.2019.06.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31227290" target="_blank">31227290</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26901005">CT in Idiopathic Pulmonary Fibrosis: Diagnosis and Beyond.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gruden JF</span><br />
|
||
<span class="medgenPMjournal">AJR Am J Roentgenol</span>
|
||
2016 Mar;206(3):495-507.
|
||
doi: 10.2214/AJR.15.15674.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26901005" target="_blank">26901005</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24361976">Headcheese sign.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chong BJ,
|
||
Kanne JP,
|
||
Chung JH</span><br />
|
||
<span class="medgenPMjournal">J Thorac Imaging</span>
|
||
2014 Jan;29(1):W13.
|
||
doi: 10.1097/RTI.0000000000000067.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24361976" target="_blank">24361976</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Interstitial%20pneumonitis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (776)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33143845">Lenalidomide-induced Interstitial Pneumonitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shafi A,
|
||
Rehman JU,
|
||
Nawaz A,
|
||
Aljohani NI</span><br />
|
||
<span class="medgenPMjournal">J Coll Physicians Surg Pak</span>
|
||
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<div class="nl"><a target="_blank" href="/pubmed/26901005">CT in Idiopathic Pulmonary Fibrosis: Diagnosis and Beyond.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Interstitial%20pneumonitis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1043)</a></div><h3 class="subhead">Prognosis</h3>
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Bigot A,
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<div class="nl"><a target="_blank" href="/pubmed/26901005">CT in Idiopathic Pulmonary Fibrosis: Diagnosis and Beyond.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gruden JF</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/26901005" target="_blank">26901005</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/1691067">Bleomycin-induced pulmonary toxicity.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Jules-Elysee K,
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Bigot A,
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</div>
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/35363197">Silica-associated systemic lupus erythematosus with lupus nephritis and lupus pneumonitis: A case report and a systematic review of the literature.</a></div>
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Fuchimoto Y,
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Watanabe M,
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Tsuji K,
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Tanabe K,
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Kinomura M,
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Kitamura S,
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Miyamoto Y,
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Wada S,
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Koyanagi T,
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Sugiyama H,
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<div class="nl"><a target="_blank" href="/pubmed/32166453">Risk stratification of pulmonary toxicities in the combination of whole lung irradiation and high-dose chemotherapy for Ewing sarcoma patients with lung metastases: a review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Scobioala S,
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<div class="nl"><a target="_blank" href="/pubmed/29770447">Effectiveness of immunoglobulin prophylaxis in reducing clinical complications of hematopoietic stem cell transplantation: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ahn H,
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Tay J,
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Shea B,
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<div class="nl"><a target="_blank" href="/pubmed/20464740">High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Yalçin B,
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<div class="nl"><a target="_blank" href="/pubmed/19114702">Immunoglobulin prophylaxis in hematopoietic stem cell transplantation: systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Raanani P,
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Gafter-Gvili A,
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Paul M,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Interstitial%20pneumonitis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10)</a></div></div>
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</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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|
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|
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|
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|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22interstitial%20pneumonitis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Interstitial%20pneumonitis%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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