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<meta name="keywords" content="C0032914, edema proteinuria hypertension gestosis, edema-proteinuria-hypertension gestosis, eph - edema, proteinuria and hypertension of pregnancy, eph complex, eph gestosis, eph toxemia, eph toxemias, finding, gestational hypertension, gestosis, edema-proteinuria-hypertension, gestosis, eph, gestosis, hypertension-edema-proteinuria, gestosis, proteinuria-edema-hypertension, hypertension edema proteinuria gestosis, hypertension induced by pregnancy, hypertension-edema-proteinuria gestosis, of pregnancies, toxemia, of pregnancy, toxemia, pathologic function, pe - pre-eclampsia, pet - pre-eclamptic toxemia, pre eclampsia, pre-eclampsia, pre-eclamptic toxaemia, pre-eclamptic toxemia, preeclampsia, preeclampsia/eclampsia, pregnancies, toxemia of, pregnancy associated hypertension, pregnancy toxaemia, pregnancy toxemia, pregnancy toxemias, pregnancy, toxemia of, proteinuria edema hypertension gestosis, proteinuria-edema-hypertension gestosis, proteinuric hypertension of pregnancy, toxaemia of pregnancy, toxemia of pregnancies, toxemia of pregnancy, toxemia, eph, toxemia, pregnancy, toxemias, eph, toxemias, pregnancy, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Preeclampsia is a complication of pregnancy in which affected women develop high blood pressure (hypertension); they can also have abnormally high levels of protein in their urine (proteinuria). This condition usually occurs in the last few months of pregnancy and often requires early delivery of the infant. However, this condition can also appear shortly after giving birth (postpartum preeclampsia).\n\nMany women with mild preeclampsia do not feel ill, and the condition is often first detected through blood pressure and urine testing in their doctor's office. In addition to hypertension and proteinuria, signs and symptoms of preeclampsia can include excessive swelling (edema) of the face or hands and a weight gain of more than 3 to 5 pounds in a week due to fluid retention. Affected women may also experience headaches, dizziness, irritability, shortness of breath, a decrease in urination, upper abdominal pain, and nausea or vomiting. Vision changes may develop, including flashing lights or spots, increased sensitivity to light (photophobia), blurry vision, or temporary blindness.\n\nIn many cases, symptoms of preeclampsia go away within a few days after the baby is born. In severe cases, however, preeclampsia can damage the mother's organs, such as the heart, liver, and kidneys, and can lead to life-threatening complications. Extremely high blood pressure in the mother can cause bleeding in the brain (hemorrhagic stroke). The effects of high blood pressure on the brain (hypertensive encephalopathy) may also result in seizures. If seizures occur, the condition is considered to have worsened to eclampsia, which can result in coma. About 1 in 200 women with untreated preeclampsia develop eclampsia. Eclampsia can also develop without any obvious signs of preeclampsia.\n\nWomen who have had preeclampsia have approximately twice the lifetime risk of heart disease and stroke than do women in the general population. Researchers suggest that preeclampsia, heart disease, and stroke may share common risk factors. Women who have diseases such as obesity, hypertension, heart disease, diabetes, or kidney disease before they become pregnant have an increased risk of developing preeclampsia. Preeclampsia is most likely to occur in a woman's first pregnancy, although it can occur in subsequent pregnancies, particularly in women with other health conditions.\n\nBetween 10 and 20 percent of women with severe preeclampsia develop another potentially life-threatening complication called HELLP syndrome. HELLP stands for hemolysis (premature red blood cell breakdown), elevated liver enzyme levels, and low platelets (cells involved in blood clotting), which are the key features of this condition.\n\nSevere preeclampsia can also affect the fetus, with impairment of blood and oxygen flow leading to growth problems or stillbirth. Infants delivered early due to preeclampsia may have complications associated with prematurity, such as breathing problems caused by underdeveloped lungs." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=18608
ConceptID=C0032914
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Preeclampsia</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18608</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C0032914</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Finding; Pathologic Function</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Edema Proteinuria Hypertension Gestosis; Edema-Proteinuria-Hypertension Gestosis; EPH Complex; EPH Gestosis; EPH Toxemia; EPH Toxemias; Gestosis, Edema-Proteinuria-Hypertension; Gestosis, EPH; Gestosis, Hypertension-Edema-Proteinuria; Gestosis, Proteinuria-Edema-Hypertension; Hypertension Edema Proteinuria Gestosis; Hypertension-Edema-Proteinuria Gestosis; Of Pregnancies, Toxemia; Of Pregnancy, Toxemia; Pre Eclampsia; Pre-Eclampsia; Pregnancies, Toxemia Of; Pregnancy Toxemia; Pregnancy Toxemias; Pregnancy, Toxemia Of; Proteinuria Edema Hypertension Gestosis; Proteinuria-Edema-Hypertension Gestosis; Toxemia Of Pregnancies; Toxemia Of Pregnancy; Toxemia, EPH; Toxemia, Pregnancy; Toxemias, EPH; Toxemias, Pregnancy</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Pre-eclampsia (398254007); EPH - Edema, proteinuria and hypertension of pregnancy (398254007); PET - Pre-eclamptic toxemia (398254007); Pre-eclamptic toxemia (398254007); PE - Pre-eclampsia (398254007); Proteinuric hypertension of pregnancy (398254007); Preeclampsia (398254007); Toxemia of pregnancy (398254007)</td></tr>
<tr><td>Modes of inheritance:</td>
<td>
<div class="divPopper rprt" id="moi_988794"><div><strong>Not genetically inherited</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>988794</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms&#10;that cannot be identified in NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">CN307044</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div></div>
<div class="spaceAbove">Source: Orphanet</div>
<div class="spaceAbove">clinical entity without genetic inheritance.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/988794">This record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_988794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Not genetically inherited</a><span> (Orphanet)</span></div></td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100602">HP:0100602</a></td></tr>
<tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0005081" target="_blank">MONDO:0005081</a></td></tr>
<tr><td>OMIM<span class="superscript">®</span> Phenotypic series:</td>
<td><a href="https://omim.org/phenotypicSeries/PS189800" target="_blank">PS189800</a></td></tr>
<tr><td>Orphanet:</td>
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&amp;Expert=275555">ORPHA275555</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Preeclampsia is a complication of pregnancy in which affected women develop high blood pressure (hypertension); they can also have abnormally high levels of protein in their urine (proteinuria). This condition usually occurs in the last few months of pregnancy and often requires early delivery of the infant. However, this condition can also appear shortly after giving birth (postpartum preeclampsia).<br /><br />Many women with mild preeclampsia do not feel ill, and the condition is often first detected through blood pressure and urine testing in their doctor's office. In addition to hypertension and proteinuria, signs and symptoms of preeclampsia can include excessive swelling (edema) of the face or hands and a weight gain of more than 3 to 5 pounds in a week due to fluid retention. Affected women may also experience headaches, dizziness, irritability, shortness of breath, a decrease in urination, upper abdominal pain, and nausea or vomiting. Vision changes may develop, including flashing lights or spots, increased sensitivity to light (photophobia), blurry vision, or temporary blindness.<br /><br />In many cases, symptoms of preeclampsia go away within a few days after the baby is born. In severe cases, however, preeclampsia can damage the mother's organs, such as the heart, liver, and kidneys, and can lead to life-threatening complications. Extremely high blood pressure in the mother can cause bleeding in the brain (hemorrhagic stroke). The effects of high blood pressure on the brain (hypertensive encephalopathy) may also result in seizures. If seizures occur, the condition is considered to have worsened to eclampsia, which can result in coma. About 1 in 200 women with untreated preeclampsia develop eclampsia. Eclampsia can also develop without any obvious signs of preeclampsia.<br /><br />Women who have had preeclampsia have approximately twice the lifetime risk of heart disease and stroke than do women in the general population. Researchers suggest that preeclampsia, heart disease, and stroke may share common risk factors. Women who have diseases such as obesity, hypertension, heart disease, diabetes, or kidney disease before they become pregnant have an increased risk of developing preeclampsia. Preeclampsia is most likely to occur in a woman's first pregnancy, although it can occur in subsequent pregnancies, particularly in women with other health conditions.<br /><br />Between 10 and 20 percent of women with severe preeclampsia develop another potentially life-threatening complication called HELLP syndrome. HELLP stands for hemolysis (premature red blood cell breakdown), elevated liver enzyme levels, and low platelets (cells involved in blood clotting), which are the key features of this condition.<br /><br />Severe preeclampsia can also affect the fetus, with impairment of blood and oxygen flow leading to growth problems or stillbirth. Infants delivered early due to preeclampsia may have complications associated with prematurity, such as breathing problems caused by underdeveloped lungs. [from <a title="MedlinePlus Genetics" href="https://medlineplus.gov/genetics/" class="defSource" target="_blank">MedlinePlus Genetics</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0032914[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=18608">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=18608" ref="ncbi_uid=18608">V</a></span></span><span class="TLline">Preeclampsia</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/272632" ref="tree=MeSH" title="MedGen record for Finding by Site or System">Finding by Site or System</a></span><ul><li><span class="TLline"><a href="/medgen/96114" ref="tree=MeSH" title="MedGen record for Cardiovascular finding">Cardiovascular finding</a></span><ul><li><span class="TLline"><a href="/medgen/224789" ref="tree=MeSH" title="MedGen record for Blood pressure finding">Blood pressure finding</a></span><ul><li><span class="TLline"><a href="/medgen/6969" ref="tree=MeSH" title="MedGen record for Hypertensive disorder">Hypertensive disorder</a></span><ul><li><span class="TLline"><a href="/medgen/852894" ref="tree=MeSH" title="MedGen record for Hypertension, pregnancy-induced">Hypertension, pregnancy-induced</a></span><ul><li><span class="matched_ds">Preeclampsia</span><ul><li><span class="TLline"><a href="/medgen/574734" ref="tree=MeSH" title="MedGen record for Severe pre-eclampsia">Severe pre-eclampsia</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&amp;data_id=156&amp;PatId=20319&amp;search=Disease_Classif_Simple&amp;new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Preeclampsia</span> in Orphanet.</div></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/32443079">Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222.</a></div>
<div class="portlet_content ln"><span class="medgenPMjournal">Obstet Gynecol</span>
2020 Jun;135(6):e237-e260.
doi: 10.1097/AOG.0000000000003891.
<span class="bold">PMID: </span><a href="/pubmed/32443079" target="_blank">32443079</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30586774">2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Grundy SM,
Stone NJ,
Bailey AL,
Beam C,
Birtcher KK,
Blumenthal RS,
Braun LT,
de Ferranti S,
Faiella-Tommasino J,
Forman DE,
Goldberg R,
Heidenreich PA,
Hlatky MA,
Jones DW,
Lloyd-Jones D,
Lopez-Pajares N,
Ndumele CE,
Orringer CE,
Peralta CA,
Saseen JJ,
Smith SC Jr,
Sperling L,
Virani SS,
Yeboah J</span><br />
<span class="medgenPMjournal">Circulation</span>
2019 Jun 18;139(25):e1082-e1143.
Epub 2018 Nov 10
doi: 10.1161/CIR.0000000000000625.
<span class="bold">PMID: </span><a href="/pubmed/30586774" target="_blank">30586774</a><a href="/pmc/articles/PMC7403606" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30575675">ACOG Practice Bulletin No. 202: Gestational Hypertension and Preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMjournal">Obstet Gynecol</span>
2019 Jan;133(1):1.
doi: 10.1097/AOG.0000000000003018.
<span class="bold">PMID: </span><a href="/pubmed/30575675" target="_blank">30575675</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22preeclampsia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1286)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng133" target="_blank">UK NICE guideline (NG133), Hypertension in pregnancy: diagnosis and management, 2023</a></h3>
</div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/38490067">Preeclampsia epidemiology(ies) and pathophysiology(ies).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Roberts JM</span><br />
<span class="medgenPMjournal">Best Pract Res Clin Obstet Gynaecol</span>
2024 Jun;94:102480.
Epub 2024 Feb 22
doi: 10.1016/j.bpobgyn.2024.102480.
<span class="bold">PMID: </span><a href="/pubmed/38490067" target="_blank">38490067</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36833689">Preeclampsia: Recent Advances in Predicting, Preventing, and Managing the Maternal and Fetal Life-Threatening Condition.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chang KJ,
Seow KM,
Chen KH</span><br />
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
2023 Feb 8;20(4)
doi: 10.3390/ijerph20042994.
<span class="bold">PMID: </span><a href="/pubmed/36833689" target="_blank">36833689</a><a href="/pmc/articles/PMC9962022" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33771361">The placenta and preeclampsia: villain or victim?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Melchiorre K,
Giorgione V,
Thilaganathan B</span><br />
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
2022 Feb;226(2S):S954-S962.
Epub 2021 Mar 24
doi: 10.1016/j.ajog.2020.10.024.
<span class="bold">PMID: </span><a href="/pubmed/33771361" target="_blank">33771361</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32926258">Preeclampsia and Kidney Disease: Deciphering Cause and Effect.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kattah A</span><br />
<span class="medgenPMjournal">Curr Hypertens Rep</span>
2020 Sep 14;22(11):91.
doi: 10.1007/s11906-020-01099-1.
<span class="bold">PMID: </span><a href="/pubmed/32926258" target="_blank">32926258</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27659865">Preeclampsia; short and long-term consequences for mother and neonate.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bokslag A,
van Weissenbruch M,
Mol BW,
de Groot CJ</span><br />
<span class="medgenPMjournal">Early Hum Dev</span>
2016 Nov;102:47-50.
Epub 2016 Sep 20
doi: 10.1016/j.earlhumdev.2016.09.007.
<span class="bold">PMID: </span><a href="/pubmed/27659865" target="_blank">27659865</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (21386)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38490067">Preeclampsia epidemiology(ies) and pathophysiology(ies).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Roberts JM</span><br />
<span class="medgenPMjournal">Best Pract Res Clin Obstet Gynaecol</span>
2024 Jun;94:102480.
Epub 2024 Feb 22
doi: 10.1016/j.bpobgyn.2024.102480.
<span class="bold">PMID: </span><a href="/pubmed/38490067" target="_blank">38490067</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36797292">Pre-eclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dimitriadis E,
Rolnik DL,
Zhou W,
Estrada-Gutierrez G,
Koga K,
Francisco RPV,
Whitehead C,
Hyett J,
da Silva Costa F,
Nicolaides K,
Menkhorst E</span><br />
<span class="medgenPMjournal">Nat Rev Dis Primers</span>
2023 Feb 16;9(1):8.
doi: 10.1038/s41572-023-00417-6.
<span class="bold">PMID: </span><a href="/pubmed/36797292" target="_blank">36797292</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34954654">Clinical tools and biomarkers to predict preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">MacDonald TM,
Walker SP,
Hannan NJ,
Tong S,
Kaitu'u-Lino TJ</span><br />
<span class="medgenPMjournal">EBioMedicine</span>
2022 Jan;75:103780.
Epub 2021 Dec 23
doi: 10.1016/j.ebiom.2021.103780.
<span class="bold">PMID: </span><a href="/pubmed/34954654" target="_blank">34954654</a><a href="/pmc/articles/PMC8718967" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33771361">The placenta and preeclampsia: villain or victim?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Melchiorre K,
Giorgione V,
Thilaganathan B</span><br />
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
2022 Feb;226(2S):S954-S962.
Epub 2021 Mar 24
doi: 10.1016/j.ajog.2020.10.024.
<span class="bold">PMID: </span><a href="/pubmed/33771361" target="_blank">33771361</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33775113">Subtypes of Preeclampsia: Recognition and Determining Clinical Usefulness.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Roberts JM,
Rich-Edwards JW,
McElrath TF,
Garmire L,
Myatt L;
Global Pregnancy Collaboration</span><br />
<span class="medgenPMjournal">Hypertension</span>
2021 May 5;77(5):1430-1441.
Epub 2021 Mar 29
doi: 10.1161/HYPERTENSIONAHA.120.14781.
<span class="bold">PMID: </span><a href="/pubmed/33775113" target="_blank">33775113</a><a href="/pmc/articles/PMC8103569" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (11278)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/38360611">The effect of Oenothera biennis (Evening primrose) oil on inflammatory diseases: a systematic review of clinical trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sharifi M,
Nourani N,
Sanaie S,
Hamedeyazdan S</span><br />
<span class="medgenPMjournal">BMC Complement Med Ther</span>
2024 Feb 15;24(1):89.
doi: 10.1186/s12906-024-04378-5.
<span class="bold">PMID: </span><a href="/pubmed/38360611" target="_blank">38360611</a><a href="/pmc/articles/PMC10867995" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38197817">Two Randomized Trials of Low-Dose Calcium Supplementation in Pregnancy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dwarkanath P,
Muhihi A,
Sudfeld CR,
Wylie BJ,
Wang M,
Perumal N,
Thomas T,
Kinyogoli SM,
Bakari M,
Fernandez R,
Raj JM,
Swai NO,
Buggi N,
Shobha R,
Sando MM,
Duggan CP,
Masanja HM,
Kurpad AV,
Pembe AB,
Fawzi WW</span><br />
<span class="medgenPMjournal">N Engl J Med</span>
2024 Jan 11;390(2):143-153.
doi: 10.1056/NEJMoa2307212.
<span class="bold">PMID: </span><a href="/pubmed/38197817" target="_blank">38197817</a><a href="/pmc/articles/PMC10921922" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36283479">Comparative effectiveness of prophylactic strategies for preeclampsia: a network meta-analysis of randomized controlled trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liu YH,
Zhang YS,
Chen JY,
Wang ZJ,
Liu YX,
Li JQ,
Xu XJ,
Xie NJ,
Lye S,
Tan N,
Duan CY,
Wei YX,
He PC</span><br />
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
2023 May;228(5):535-546.
Epub 2022 Oct 23
doi: 10.1016/j.ajog.2022.10.014.
<span class="bold">PMID: </span><a href="/pubmed/36283479" target="_blank">36283479</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32835720">Prevention of preeclampsia with aspirin.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rolnik DL,
Nicolaides KH,
Poon LC</span><br />
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
2022 Feb;226(2S):S1108-S1119.
Epub 2020 Aug 21
doi: 10.1016/j.ajog.2020.08.045.
<span class="bold">PMID: </span><a href="/pubmed/32835720" target="_blank">32835720</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28657417">Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rolnik DL,
Wright D,
Poon LC,
O'Gorman N,
Syngelaki A,
de Paco Matallana C,
Akolekar R,
Cicero S,
Janga D,
Singh M,
Molina FS,
Persico N,
Jani JC,
Plasencia W,
Papaioannou G,
Tenenbaum-Gavish K,
Meiri H,
Gizurarson S,
Maclagan K,
Nicolaides KH</span><br />
<span class="medgenPMjournal">N Engl J Med</span>
2017 Aug 17;377(7):613-622.
Epub 2017 Jun 28
doi: 10.1056/NEJMoa1704559.
<span class="bold">PMID: </span><a href="/pubmed/28657417" target="_blank">28657417</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7391)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/36328676">Maternal Mortality in Low and Middle-Income Countries.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lawrence ER,
Klein TJ,
Beyuo TK</span><br />
<span class="medgenPMjournal">Obstet Gynecol Clin North Am</span>
2022 Dec;49(4):713-733.
doi: 10.1016/j.ogc.2022.07.001.
<span class="bold">PMID: </span><a href="/pubmed/36328676" target="_blank">36328676</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33903001">When and how should I transfuse during obstetric hemorrhage?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Waters JH,
Bonnet MP</span><br />
<span class="medgenPMjournal">Int J Obstet Anesth</span>
2021 May;46:102973.
Epub 2021 Mar 11
doi: 10.1016/j.ijoa.2021.102973.
<span class="bold">PMID: </span><a href="/pubmed/33903001" target="_blank">33903001</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29039130">Aspirin for Prevention of Preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Atallah A,
Lecarpentier E,
Goffinet F,
Doret-Dion M,
Gaucherand P,
Tsatsaris V</span><br />
<span class="medgenPMjournal">Drugs</span>
2017 Nov;77(17):1819-1831.
doi: 10.1007/s40265-017-0823-0.
<span class="bold">PMID: </span><a href="/pubmed/29039130" target="_blank">29039130</a><a href="/pmc/articles/PMC5681618" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28228456">Preeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wu P,
Haththotuwa R,
Kwok CS,
Babu A,
Kotronias RA,
Rushton C,
Zaman A,
Fryer AA,
Kadam U,
Chew-Graham CA,
Mamas MA</span><br />
<span class="medgenPMjournal">Circ Cardiovasc Qual Outcomes</span>
2017 Feb;10(2)
Epub 2017 Feb 22
doi: 10.1161/CIRCOUTCOMES.116.003497.
<span class="bold">PMID: </span><a href="/pubmed/28228456" target="_blank">28228456</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23746796">Global and regional estimates of preeclampsia and eclampsia: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abalos E,
Cuesta C,
Grosso AL,
Chou D,
Say L</span><br />
<span class="medgenPMjournal">Eur J Obstet Gynecol Reprod Biol</span>
2013 Sep;170(1):1-7.
Epub 2013 Jun 7
doi: 10.1016/j.ejogrb.2013.05.005.
<span class="bold">PMID: </span><a href="/pubmed/23746796" target="_blank">23746796</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8438)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/38705648">Predicting Preterm Birth Using Proteomics.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Marić I,
Stevenson DK,
Aghaeepour N,
Gaudillière B,
Wong RJ,
Angst MS</span><br />
<span class="medgenPMjournal">Clin Perinatol</span>
2024 Jun;51(2):391-409.
Epub 2024 Mar 23
doi: 10.1016/j.clp.2024.02.011.
<span class="bold">PMID: </span><a href="/pubmed/38705648" target="_blank">38705648</a><a href="/pmc/articles/PMC11186213" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35816445">Clinical utility of sFlt-1 and PlGF in screening, prediction, diagnosis and monitoring of pre-eclampsia and fetal growth restriction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stepan H,
Galindo A,
Hund M,
Schlembach D,
Sillman J,
Surbek D,
Vatish M</span><br />
<span class="medgenPMjournal">Ultrasound Obstet Gynecol</span>
2023 Feb;61(2):168-180.
doi: 10.1002/uog.26032.
<span class="bold">PMID: </span><a href="/pubmed/35816445" target="_blank">35816445</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34954654">Clinical tools and biomarkers to predict preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">MacDonald TM,
Walker SP,
Hannan NJ,
Tong S,
Kaitu'u-Lino TJ</span><br />
<span class="medgenPMjournal">EBioMedicine</span>
2022 Jan;75:103780.
Epub 2021 Dec 23
doi: 10.1016/j.ebiom.2021.103780.
<span class="bold">PMID: </span><a href="/pubmed/34954654" target="_blank">34954654</a><a href="/pmc/articles/PMC8718967" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27722963">Superimposed Preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Guedes-Martins L</span><br />
<span class="medgenPMjournal">Adv Exp Med Biol</span>
2017;956:409-417.
doi: 10.1007/5584_2016_82.
<span class="bold">PMID: </span><a href="/pubmed/27722963" target="_blank">27722963</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26735990">Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zeisler H,
Llurba E,
Chantraine F,
Vatish M,
Staff AC,
Sennström M,
Olovsson M,
Brennecke SP,
Stepan H,
Allegranza D,
Dilba P,
Schoedl M,
Hund M,
Verlohren S</span><br />
<span class="medgenPMjournal">N Engl J Med</span>
2016 Jan 7;374(1):13-22.
doi: 10.1056/NEJMoa1414838.
<span class="bold">PMID: </span><a href="/pubmed/26735990" target="_blank">26735990</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10984)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/38421424">Advances in pathogenesis of preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yang M,
Wang M,
Li N</span><br />
<span class="medgenPMjournal">Arch Gynecol Obstet</span>
2024 May;309(5):1815-1823.
Epub 2024 Feb 29
doi: 10.1007/s00404-024-07393-6.
<span class="bold">PMID: </span><a href="/pubmed/38421424" target="_blank">38421424</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35255260">Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Toloza FJK,
Derakhshan A,
Männistö T,
Bliddal S,
Popova PV,
Carty DM,
Chen L,
Taylor P,
Mosso L,
Oken E,
Suvanto E,
Itoh S,
Kishi R,
Bassols J,
Auvinen J,
López-Bermejo A,
Brown SJ,
Boucai L,
Hisada A,
Yoshinaga J,
Shilova E,
Grineva EN,
Vrijkotte TGM,
Sunyer J,
Jiménez-Zabala A,
Riaño-Galan I,
Lopez-Espinosa MJ,
Prokop LJ,
Singh Ospina N,
Brito JP,
Rodriguez-Gutierrez R,
Alexander EK,
Chaker L,
Pearce EN,
Peeters RP,
Feldt-Rasmussen U,
Guxens M,
Chatzi L,
Delles C,
Roeters van Lennep JE,
Pop VJM,
Lu X,
Walsh JP,
Nelson SM,
Korevaar TIM,
Maraka S</span><br />
<span class="medgenPMjournal">Lancet Diabetes Endocrinol</span>
2022 Apr;10(4):243-252.
Epub 2022 Mar 4
doi: 10.1016/S2213-8587(22)00007-9.
<span class="bold">PMID: </span><a href="/pubmed/35255260" target="_blank">35255260</a><a href="/pmc/articles/PMC10314731" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32315307">Systematic review of prediction models for gestational hypertension and preeclampsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Antwi E,
Amoakoh-Coleman M,
Vieira DL,
Madhavaram S,
Koram KA,
Grobbee DE,
Agyepong IA,
Klipstein-Grobusch K</span><br />
<span class="medgenPMjournal">PLoS One</span>
2020;15(4):e0230955.
Epub 2020 Apr 21
doi: 10.1371/journal.pone.0230955.
<span class="bold">PMID: </span><a href="/pubmed/32315307" target="_blank">32315307</a><a href="/pmc/articles/PMC7173928" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28228456">Preeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wu P,
Haththotuwa R,
Kwok CS,
Babu A,
Kotronias RA,
Rushton C,
Zaman A,
Fryer AA,
Kadam U,
Chew-Graham CA,
Mamas MA</span><br />
<span class="medgenPMjournal">Circ Cardiovasc Qual Outcomes</span>
2017 Feb;10(2)
Epub 2017 Feb 22
doi: 10.1161/CIRCOUTCOMES.116.003497.
<span class="bold">PMID: </span><a href="/pubmed/28228456" target="_blank">28228456</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23746796">Global and regional estimates of preeclampsia and eclampsia: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abalos E,
Cuesta C,
Grosso AL,
Chou D,
Say L</span><br />
<span class="medgenPMjournal">Eur J Obstet Gynecol Reprod Biol</span>
2013 Sep;170(1):1-7.
Epub 2013 Jun 7
doi: 10.1016/j.ejogrb.2013.05.005.
<span class="bold">PMID: </span><a href="/pubmed/23746796" target="_blank">23746796</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1244)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0032914%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (8)</a></li>
<li><a href="/gtr/tests?term=C0032914%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (9)</a></li>
<li><a href="/gtr/tests?term=C0032914%5bDISCUI%5d&amp;filter=method%3A2%5F19" target="_blank">Targeted variant analysis (2)</a></li>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22preeclampsia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Preeclampsia%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng133">NICE, 2023</a><div>UK NICE guideline (NG133), Hypertension in pregnancy: diagnosis and management, 2023</div></li></ul></div>
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