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<meta name="keywords" content="C0023222, leg pain, lower limb pain, pain in leg, pain in lower limb, sign or symptom, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the leg." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Lower limb pain (Concept Id: C0023222)
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<!--
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UID=6033
|
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ConceptID=C0023222
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Lower limb pain</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>6033</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0023222</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Sign or Symptom</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Leg pain</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Leg pain (10601006); Pain in lower limb (10601006); Pain in leg (10601006)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0012514">HP:0012514</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the leg. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
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||
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||
<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Lower limb pain</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/3593" ref="tree=MeSH" title="MedGen record for Constitutional symptom">Constitutional symptom</a></span><ul><li><span class="TLline"><a href="/medgen/45282" ref="tree=MeSH" title="MedGen record for Pain">Pain</a></span><ul><li><span class="TLline"><a href="/medgen/10540" ref="tree=MeSH" title="MedGen record for Limb pain">Limb pain</a></span><ul><li><span class="matched_ds">Lower limb pain</span><ul><li><span class="TLline"><a href="/medgen/116068" ref="tree=MeSH" title="MedGen record for Ankle pain">Ankle pain</a></span></li><li><span class="TLline"><a href="/medgen/42074" ref="tree=MeSH" title="MedGen record for Foot pain">Foot pain</a></span><ul><li><span class="TLline"><a href="/medgen/1055344" ref="tree=MeSH" title="MedGen record for Pain on the lateral aspect of the foot">Pain on the lateral aspect of the foot</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/65421" ref="tree=MeSH" title="MedGen record for Knee pain">Knee pain</a></span><ul><li><span class="TLline"><a href="/medgen/1057379" ref="tree=MeSH" title="MedGen record for Pain at the anterior aspect of the knee">Pain at the anterior aspect of the knee</a></span></li><li><span class="TLline"><a href="/medgen/1055934" ref="tree=MeSH" title="MedGen record for Pain at the lateral aspect of the knee">Pain at the lateral aspect of the knee</a></span></li><li><span class="TLline"><a href="/medgen/1056854" ref="tree=MeSH" title="MedGen record for Pain at the medial aspect of the knee">Pain at the medial aspect of the knee</a></span></li><li><span class="TLline"><a href="/medgen/1057260" ref="tree=MeSH" title="MedGen record for Pain at the posterior aspect of the knee">Pain at the posterior aspect of the knee</a></span></li><li><span class="TLline"><a href="/medgen/534017" ref="tree=MeSH" title="MedGen record for Wilson sign">Wilson sign</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/107444" ref="tree=MeSH" title="MedGen record for Lower Thigh Pain">Lower Thigh Pain</a></span></li><li><span class="TLline"><a href="/medgen/537055" ref="tree=MeSH" title="MedGen record for Toe pain">Toe pain</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_4268"><div><strong>Diaphyseal dysplasia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>4268</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0011989</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Camurati-Engelmann disease (CED) is characterized by hyperostosis of the long bones and the skull, proximal muscle weakness, limb pain, a wide-based, waddling gait, and joint contractures. Facial features such as macrocephaly, frontal bossing, enlargement of the mandible, proptosis, and cranial nerve impingement resulting in facial palsy are seen in severely affected individuals later in life.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/4268">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_342358"><div><strong>Pili torti-developmental delay-neurological abnormalities syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>342358</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1849811</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Abnormal hair, joint laxity, and developmental delay (HJDD) is characterized by normal hair at birth that gradually becomes sparse, twisted, brittle, and easily broken, with pili torti and trichorrhexis nodosa observed on light microscopy. Other features include increased joint mobility and cognitive delay (summary by Sharma et al., 2019).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/342358">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_355875"><div><strong>Osteosclerosis-ichthyosis-premature ovarian failure syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>355875</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1864942</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare genetic disease characterized by sclerosing dysplasia affecting the diaphyseal and metaphyseal regions of the long bones, as well as the skull and metacarpals, in association with skin changes like those seen in ichthyosis vulgaris and premature ovarian failure with bilateral hypoplasia of the ovaries. Patients present in adulthood, primarily with swelling of the extremities and occasional mild pain in the legs.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/355875">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_435869"><div><strong>Familial cold autoinflammatory syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>435869</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2673198</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial cold autoinflammatory syndrome-2 (FCAS2) is an autosomal dominant autoinflammatory disorder characterized by episodic and recurrent rash, urticaria, arthralgia, myalgia, and headache. In most patients, these episodes are accompanied by fever and serologic evidence of inflammation. Most, but not all, patients report exposure to cold as a trigger for the episodes. Additional features may include abdominal pain, thoracic pain, and sensorineural deafness. The age at onset is variable, ranging from the first year of life to middle age, and the severity and clinical manifestations are heterogeneous (summary by Shen et al., 2017). For a phenotypic description and a discussion of genetic heterogeneity of familial cold autoinflammatory syndrome, see FCAS1 (120100).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/435869">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_436979"><div><strong>Dystonia 16</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>436979</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2677567</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Dystonia 16 is one of many forms of dystonia, which is a group of conditions characterized by involuntary movements, twisting (torsion) and tensing of various muscles, and unusual positioning of affected body parts. Dystonia 16 can appear at any age from infancy through adulthood, although it most often begins in childhood.\n\nThe signs and symptoms of dystonia 16 vary among people with the condition. In many affected individuals, the disorder first affects muscles in one or both arms or legs. Tensing (contraction) of the muscles often sets the affected limb in an abnormal position, which may be painful and can lead to difficulty performing tasks, such as walking. In others, muscles in the neck are affected first, causing the head to be pulled backward and positioned with the chin in the air (retrocollis).\n\nIn dystonia 16, muscles of the jaw, lips, and tongue are also commonly affected (oromandibular dystonia), causing difficulty opening and closing the mouth and problems with swallowing and speech. Speech can also be affected by involuntary tensing of the muscles that control the vocal cords (laryngeal dystonia), resulting in a quiet, breathy voice or an inability to speak clearly. Dystonia 16 gradually gets worse, eventually involving muscles in most parts of the body.\n\nSome people with dystonia 16 develop a pattern of movement abnormalities known as parkinsonism. These abnormalities include unusually slow movement (bradykinesia), muscle rigidity, tremors, and an inability to hold the body upright and balanced (postural instability). In dystonia 16, parkinsonism is relatively mild if it develops at all.\n\nThe signs and symptoms of dystonia 16 usually do not get better when treated with drugs that are typically used for movement disorders.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/436979">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_419470"><div><strong>Camurati-Engelmann disease, type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>419470</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2931683</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Camurati-Engelmann Disease not associated with TGFB1. This is an n-of-1 use case where only one patient or family has been described with this disorder.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/419470">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_934730"><div><strong>Spinocerebellar ataxia 43</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>934730</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4310763</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Spinocerebellar ataxia-43 (SCA43) is an autosomal dominant, slowly progressive neurologic disorder characterized by adult-onset gait and limb ataxia and often associated with peripheral neuropathy mainly affecting the motor system, although some patients may have distal sensory impairment (summary by Depondt et al., 2016). For a general discussion of autosomal dominant spinocerebellar ataxia, see SCA1 (164400).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/934730">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648461"><div><strong>Charcot-Marie-Tooth disease type 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648461</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4721916</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary motor and sensory neuropathies (HMSN) are a heterogeneous group of peripheral nervous system disorders affecting motor and sensory function. HMSN I, also known as Charcot-Marie-Tooth (CMT) disease, or peroneal muscular atrophy, type 1, is a demyelinating neuropathy (see CMT1B; 118200) and HMSN II, also known as CMT type 2, is an axonal neuropathy (see CMT2A1; 118210). See also HMSN III (145900) and HMSN IV (266500). For an autosomal recessive disorder with similarities to HMSN V, see 607731.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648461">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1748867"><div><strong>Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1748867</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5399977</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Mitochondrial complex IV deficiency nuclear type 2 (MC4DN2) is an autosomal recessive multisystem metabolic disorder characterized by the onset of symptoms at birth or in the first weeks or months of life. Affected individuals have severe hypotonia, often associated with feeding difficulties and respiratory insufficiency necessitating tube feeding and mechanical ventilation. The vast majority of patients develop hypertrophic cardiomyopathy in the first days or weeks of life, which usually leads to death in infancy or early childhood. Patients also show neurologic abnormalities, including developmental delay, nystagmus, fasciculations, dystonia, EEG changes, and brain imaging abnormalities compatible with a diagnosis of Leigh syndrome (see 256000). There may also be evidence of systemic involvement with hepatomegaly and myopathy, although neurogenic muscle atrophy is more common and may resemble spinal muscular atrophy type I (SMA1; 253300). Serum lactate is increased, and laboratory studies show decreased mitochondrial complex IV protein and activity levels in various tissues, including heart and skeletal muscle. Most patients die in infancy of cardiorespiratory failure (summary by Papadopoulou et al., 1999). For a discussion of genetic heterogeneity of mitochondrial complex IV (cytochrome c oxidase) deficiency, see 220110.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1748867">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1800473"><div><strong>Charcot-Marie-Tooth disease axonal type 2V</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1800473</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5569050</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare axonal hereditary motor and sensory neuropathy characterized by adult onset of recurrent pain in legs with or without cramps, progressive loss of deep tendon reflexes and vibration sense, paresthesia in the feet and later in the hands. Patients often experience sleep disturbances and mild sensory ataxia.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1800473">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_419470" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Camurati-Engelmann disease, type 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1748867" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1800473" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth disease axonal type 2V</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648461" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth disease type 5</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_4268" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Diaphyseal dysplasia</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (10)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_436979" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Dystonia 16</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_435869" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial cold autoinflammatory syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_355875" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Osteosclerosis-ichthyosis-premature ovarian failure syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_342358" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pili torti-developmental delay-neurological abnormalities syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_934730" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Spinocerebellar ataxia 43</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/24643353">Lumbar sympathetic treatment in the management of lower limb pain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Abramov R</span><br />
|
||
<span class="medgenPMjournal">Curr Pain Headache Rep</span>
|
||
2014 Apr;18(4):403.
|
||
doi: 10.1007/s11916-014-0403-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24643353" target="_blank">24643353</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17992416">Guidelines for the diagnosis and treatment of schistosomal myeloradiculopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lambertucci JR,
|
||
Silva LC,
|
||
do Amaral RS</span><br />
|
||
<span class="medgenPMjournal">Rev Soc Bras Med Trop</span>
|
||
2007 Sep-Oct;40(5):574-81.
|
||
doi: 10.1590/s0037-86822007000500016.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17992416" target="_blank">17992416</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17350549">Strategies for prevention and management of musculoskeletal conditions. Lower limb pain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dreinhöfer KE,
|
||
Reichel H,
|
||
Käfer W</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Rheumatol</span>
|
||
2007 Feb;21(1):135-52.
|
||
doi: 10.1016/j.berh.2006.10.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17350549" target="_blank">17350549</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22lower%20limb%20pain%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (29)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36749265">Percutaneous endoscopic lumbar discectomy for L5-S1 disc herniation based on image analysis and clinical findings: A retrospective review of 345 cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shen SC,
|
||
Chen HC,
|
||
Tsou HK,
|
||
Lin RH,
|
||
Shih YT,
|
||
Huang CW,
|
||
Tang CL,
|
||
Chen HT,
|
||
Chang CC,
|
||
Tzeng CY</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2023 Feb 3;102(5):e32832.
|
||
doi: 10.1097/MD.0000000000032832.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36749265" target="_blank">36749265</a><a href="/pmc/articles/PMC9901959" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33818600">Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petersen EA,
|
||
Stauss TG,
|
||
Scowcroft JA,
|
||
Brooks ES,
|
||
White JL,
|
||
Sills SM,
|
||
Amirdelfan K,
|
||
Guirguis MN,
|
||
Xu J,
|
||
Yu C,
|
||
Nairizi A,
|
||
Patterson DG,
|
||
Tsoulfas KC,
|
||
Creamer MJ,
|
||
Galan V,
|
||
Bundschu RH,
|
||
Paul CA,
|
||
Mehta ND,
|
||
Choi H,
|
||
Sayed D,
|
||
Lad SP,
|
||
DiBenedetto DJ,
|
||
Sethi KA,
|
||
Goree JH,
|
||
Bennett MT,
|
||
Harrison NJ,
|
||
Israel AF,
|
||
Chang P,
|
||
Wu PW,
|
||
Gekht G,
|
||
Argoff CE,
|
||
Nasr CE,
|
||
Taylor RS,
|
||
Subbaroyan J,
|
||
Gliner BE,
|
||
Caraway DL,
|
||
Mekhail NA</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2021 Jun 1;78(6):687-698.
|
||
doi: 10.1001/jamaneurol.2021.0538.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33818600" target="_blank">33818600</a><a href="/pmc/articles/PMC8022268" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31073921">Safety of Oral Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Osteoarthritis: What Does the Literature Say?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cooper C,
|
||
Chapurlat R,
|
||
Al-Daghri N,
|
||
Herrero-Beaumont G,
|
||
Bruyère O,
|
||
Rannou F,
|
||
Roth R,
|
||
Uebelhart D,
|
||
Reginster JY</span><br />
|
||
<span class="medgenPMjournal">Drugs Aging</span>
|
||
2019 Apr;36(Suppl 1):15-24.
|
||
doi: 10.1007/s40266-019-00660-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31073921" target="_blank">31073921</a><a href="/pmc/articles/PMC6509083" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24796917">Popliteal artery entrapment syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lejay A,
|
||
Ohana M,
|
||
Lee JT,
|
||
Georg Y,
|
||
Delay C,
|
||
Lucereau B,
|
||
Thaveau F,
|
||
Gaertner S,
|
||
Chakfé N;
|
||
Groupe Européen de Recherche sur les Prothèses Appliquées à la Chirurgie Vasculaire (GEPROVAS)</span><br />
|
||
<span class="medgenPMjournal">J Cardiovasc Surg (Torino)</span>
|
||
2014 Apr;55(2 Suppl 1):225-37.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24796917" target="_blank">24796917</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16461960">Prediction of pulmonary embolism in the emergency department: the revised Geneva score.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Le Gal G,
|
||
Righini M,
|
||
Roy PM,
|
||
Sanchez O,
|
||
Aujesky D,
|
||
Bounameaux H,
|
||
Perrier A</span><br />
|
||
<span class="medgenPMjournal">Ann Intern Med</span>
|
||
2006 Feb 7;144(3):165-71.
|
||
doi: 10.7326/0003-4819-144-3-200602070-00004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16461960" target="_blank">16461960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lower%20limb%20pain%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (243)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/40035153">A Nomogram for Predicting Pulmonary Embolism in Silicosis Patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhou J,
|
||
Du W,
|
||
Liu J,
|
||
Peng L</span><br />
|
||
<span class="medgenPMjournal">Clin Respir J</span>
|
||
2025 Mar;19(3):e70059.
|
||
doi: 10.1111/crj.70059.
|
||
<span class="bold">PMID: </span><a href="/pubmed/40035153" target="_blank">40035153</a><a href="/pmc/articles/PMC11876996" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38744456">Of oranges and lemons: you are what you eat.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sangaran R,
|
||
Smith JP,
|
||
Menegotto F,
|
||
Ramanan AV</span><br />
|
||
<span class="medgenPMjournal">Arch Dis Child Educ Pract Ed</span>
|
||
2024 Nov 21;109(6):301-305.
|
||
doi: 10.1136/archdischild-2024-327057.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38744456" target="_blank">38744456</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36378230">Lower limb pain and edema due to thyroid dermopathy: an unusual presentation of Graves disease in an adolescent patient.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Berlingieri DM,
|
||
Moras LA,
|
||
Scliar C</span><br />
|
||
<span class="medgenPMjournal">Arch Argent Pediatr</span>
|
||
2023 Apr 1;121(2):e202202615.
|
||
Epub 2022 Nov 17
|
||
doi: 10.5546/aap.2022-02615.eng.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36378230" target="_blank">36378230</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33818600">Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petersen EA,
|
||
Stauss TG,
|
||
Scowcroft JA,
|
||
Brooks ES,
|
||
White JL,
|
||
Sills SM,
|
||
Amirdelfan K,
|
||
Guirguis MN,
|
||
Xu J,
|
||
Yu C,
|
||
Nairizi A,
|
||
Patterson DG,
|
||
Tsoulfas KC,
|
||
Creamer MJ,
|
||
Galan V,
|
||
Bundschu RH,
|
||
Paul CA,
|
||
Mehta ND,
|
||
Choi H,
|
||
Sayed D,
|
||
Lad SP,
|
||
DiBenedetto DJ,
|
||
Sethi KA,
|
||
Goree JH,
|
||
Bennett MT,
|
||
Harrison NJ,
|
||
Israel AF,
|
||
Chang P,
|
||
Wu PW,
|
||
Gekht G,
|
||
Argoff CE,
|
||
Nasr CE,
|
||
Taylor RS,
|
||
Subbaroyan J,
|
||
Gliner BE,
|
||
Caraway DL,
|
||
Mekhail NA</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2021 Jun 1;78(6):687-698.
|
||
doi: 10.1001/jamaneurol.2021.0538.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33818600" target="_blank">33818600</a><a href="/pmc/articles/PMC8022268" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16461960">Prediction of pulmonary embolism in the emergency department: the revised Geneva score.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Le Gal G,
|
||
Righini M,
|
||
Roy PM,
|
||
Sanchez O,
|
||
Aujesky D,
|
||
Bounameaux H,
|
||
Perrier A</span><br />
|
||
<span class="medgenPMjournal">Ann Intern Med</span>
|
||
2006 Feb 7;144(3):165-71.
|
||
doi: 10.7326/0003-4819-144-3-200602070-00004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16461960" target="_blank">16461960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lower%20limb%20pain%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (201)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35380727">Scurvy in Children: The Silent Masquerader.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Subhash S,
|
||
Santosh ST</span><br />
|
||
<span class="medgenPMjournal">J Trop Pediatr</span>
|
||
2022 Apr 5;68(3)
|
||
doi: 10.1093/tropej/fmac029.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35380727" target="_blank">35380727</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34192807">Cilostazol for intermittent claudication.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brown T,
|
||
Forster RB,
|
||
Cleanthis M,
|
||
Mikhailidis DP,
|
||
Stansby G,
|
||
Stewart M</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2021 Jun 30;6(6):CD003748.
|
||
doi: 10.1002/14651858.CD003748.pub5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34192807" target="_blank">34192807</a><a href="/pmc/articles/PMC8245159" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33818600">Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petersen EA,
|
||
Stauss TG,
|
||
Scowcroft JA,
|
||
Brooks ES,
|
||
White JL,
|
||
Sills SM,
|
||
Amirdelfan K,
|
||
Guirguis MN,
|
||
Xu J,
|
||
Yu C,
|
||
Nairizi A,
|
||
Patterson DG,
|
||
Tsoulfas KC,
|
||
Creamer MJ,
|
||
Galan V,
|
||
Bundschu RH,
|
||
Paul CA,
|
||
Mehta ND,
|
||
Choi H,
|
||
Sayed D,
|
||
Lad SP,
|
||
DiBenedetto DJ,
|
||
Sethi KA,
|
||
Goree JH,
|
||
Bennett MT,
|
||
Harrison NJ,
|
||
Israel AF,
|
||
Chang P,
|
||
Wu PW,
|
||
Gekht G,
|
||
Argoff CE,
|
||
Nasr CE,
|
||
Taylor RS,
|
||
Subbaroyan J,
|
||
Gliner BE,
|
||
Caraway DL,
|
||
Mekhail NA</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2021 Jun 1;78(6):687-698.
|
||
doi: 10.1001/jamaneurol.2021.0538.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33818600" target="_blank">33818600</a><a href="/pmc/articles/PMC8022268" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31073921">Safety of Oral Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Osteoarthritis: What Does the Literature Say?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cooper C,
|
||
Chapurlat R,
|
||
Al-Daghri N,
|
||
Herrero-Beaumont G,
|
||
Bruyère O,
|
||
Rannou F,
|
||
Roth R,
|
||
Uebelhart D,
|
||
Reginster JY</span><br />
|
||
<span class="medgenPMjournal">Drugs Aging</span>
|
||
2019 Apr;36(Suppl 1):15-24.
|
||
doi: 10.1007/s40266-019-00660-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31073921" target="_blank">31073921</a><a href="/pmc/articles/PMC6509083" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17992416">Guidelines for the diagnosis and treatment of schistosomal myeloradiculopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lambertucci JR,
|
||
Silva LC,
|
||
do Amaral RS</span><br />
|
||
<span class="medgenPMjournal">Rev Soc Bras Med Trop</span>
|
||
2007 Sep-Oct;40(5):574-81.
|
||
doi: 10.1590/s0037-86822007000500016.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17992416" target="_blank">17992416</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lower%20limb%20pain%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (164)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/40035153">A Nomogram for Predicting Pulmonary Embolism in Silicosis Patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhou J,
|
||
Du W,
|
||
Liu J,
|
||
Peng L</span><br />
|
||
<span class="medgenPMjournal">Clin Respir J</span>
|
||
2025 Mar;19(3):e70059.
|
||
doi: 10.1111/crj.70059.
|
||
<span class="bold">PMID: </span><a href="/pubmed/40035153" target="_blank">40035153</a><a href="/pmc/articles/PMC11876996" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35864176">Defining Growing Pains: A Scoping Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Keeffe M,
|
||
Kamper SJ,
|
||
Montgomery L,
|
||
Williams A,
|
||
Martiniuk A,
|
||
Lucas B,
|
||
Dario AB,
|
||
Rathleff MS,
|
||
Hestbaek L,
|
||
Williams CM</span><br />
|
||
<span class="medgenPMjournal">Pediatrics</span>
|
||
2022 Aug 1;150(2)
|
||
doi: 10.1542/peds.2021-052578.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35864176" target="_blank">35864176</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33818600">Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petersen EA,
|
||
Stauss TG,
|
||
Scowcroft JA,
|
||
Brooks ES,
|
||
White JL,
|
||
Sills SM,
|
||
Amirdelfan K,
|
||
Guirguis MN,
|
||
Xu J,
|
||
Yu C,
|
||
Nairizi A,
|
||
Patterson DG,
|
||
Tsoulfas KC,
|
||
Creamer MJ,
|
||
Galan V,
|
||
Bundschu RH,
|
||
Paul CA,
|
||
Mehta ND,
|
||
Choi H,
|
||
Sayed D,
|
||
Lad SP,
|
||
DiBenedetto DJ,
|
||
Sethi KA,
|
||
Goree JH,
|
||
Bennett MT,
|
||
Harrison NJ,
|
||
Israel AF,
|
||
Chang P,
|
||
Wu PW,
|
||
Gekht G,
|
||
Argoff CE,
|
||
Nasr CE,
|
||
Taylor RS,
|
||
Subbaroyan J,
|
||
Gliner BE,
|
||
Caraway DL,
|
||
Mekhail NA</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2021 Jun 1;78(6):687-698.
|
||
doi: 10.1001/jamaneurol.2021.0538.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33818600" target="_blank">33818600</a><a href="/pmc/articles/PMC8022268" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24796917">Popliteal artery entrapment syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lejay A,
|
||
Ohana M,
|
||
Lee JT,
|
||
Georg Y,
|
||
Delay C,
|
||
Lucereau B,
|
||
Thaveau F,
|
||
Gaertner S,
|
||
Chakfé N;
|
||
Groupe Européen de Recherche sur les Prothèses Appliquées à la Chirurgie Vasculaire (GEPROVAS)</span><br />
|
||
<span class="medgenPMjournal">J Cardiovasc Surg (Torino)</span>
|
||
2014 Apr;55(2 Suppl 1):225-37.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24796917" target="_blank">24796917</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16461960">Prediction of pulmonary embolism in the emergency department: the revised Geneva score.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Le Gal G,
|
||
Righini M,
|
||
Roy PM,
|
||
Sanchez O,
|
||
Aujesky D,
|
||
Bounameaux H,
|
||
Perrier A</span><br />
|
||
<span class="medgenPMjournal">Ann Intern Med</span>
|
||
2006 Feb 7;144(3):165-71.
|
||
doi: 10.7326/0003-4819-144-3-200602070-00004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16461960" target="_blank">16461960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lower%20limb%20pain%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (108)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36749265">Percutaneous endoscopic lumbar discectomy for L5-S1 disc herniation based on image analysis and clinical findings: A retrospective review of 345 cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shen SC,
|
||
Chen HC,
|
||
Tsou HK,
|
||
Lin RH,
|
||
Shih YT,
|
||
Huang CW,
|
||
Tang CL,
|
||
Chen HT,
|
||
Chang CC,
|
||
Tzeng CY</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2023 Feb 3;102(5):e32832.
|
||
doi: 10.1097/MD.0000000000032832.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36749265" target="_blank">36749265</a><a href="/pmc/articles/PMC9901959" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33818600">Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petersen EA,
|
||
Stauss TG,
|
||
Scowcroft JA,
|
||
Brooks ES,
|
||
White JL,
|
||
Sills SM,
|
||
Amirdelfan K,
|
||
Guirguis MN,
|
||
Xu J,
|
||
Yu C,
|
||
Nairizi A,
|
||
Patterson DG,
|
||
Tsoulfas KC,
|
||
Creamer MJ,
|
||
Galan V,
|
||
Bundschu RH,
|
||
Paul CA,
|
||
Mehta ND,
|
||
Choi H,
|
||
Sayed D,
|
||
Lad SP,
|
||
DiBenedetto DJ,
|
||
Sethi KA,
|
||
Goree JH,
|
||
Bennett MT,
|
||
Harrison NJ,
|
||
Israel AF,
|
||
Chang P,
|
||
Wu PW,
|
||
Gekht G,
|
||
Argoff CE,
|
||
Nasr CE,
|
||
Taylor RS,
|
||
Subbaroyan J,
|
||
Gliner BE,
|
||
Caraway DL,
|
||
Mekhail NA</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2021 Jun 1;78(6):687-698.
|
||
doi: 10.1001/jamaneurol.2021.0538.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33818600" target="_blank">33818600</a><a href="/pmc/articles/PMC8022268" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31073921">Safety of Oral Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Osteoarthritis: What Does the Literature Say?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cooper C,
|
||
Chapurlat R,
|
||
Al-Daghri N,
|
||
Herrero-Beaumont G,
|
||
Bruyère O,
|
||
Rannou F,
|
||
Roth R,
|
||
Uebelhart D,
|
||
Reginster JY</span><br />
|
||
<span class="medgenPMjournal">Drugs Aging</span>
|
||
2019 Apr;36(Suppl 1):15-24.
|
||
doi: 10.1007/s40266-019-00660-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31073921" target="_blank">31073921</a><a href="/pmc/articles/PMC6509083" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24796917">Popliteal artery entrapment syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lejay A,
|
||
Ohana M,
|
||
Lee JT,
|
||
Georg Y,
|
||
Delay C,
|
||
Lucereau B,
|
||
Thaveau F,
|
||
Gaertner S,
|
||
Chakfé N;
|
||
Groupe Européen de Recherche sur les Prothèses Appliquées à la Chirurgie Vasculaire (GEPROVAS)</span><br />
|
||
<span class="medgenPMjournal">J Cardiovasc Surg (Torino)</span>
|
||
2014 Apr;55(2 Suppl 1):225-37.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24796917" target="_blank">24796917</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16461960">Prediction of pulmonary embolism in the emergency department: the revised Geneva score.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Le Gal G,
|
||
Righini M,
|
||
Roy PM,
|
||
Sanchez O,
|
||
Aujesky D,
|
||
Bounameaux H,
|
||
Perrier A</span><br />
|
||
<span class="medgenPMjournal">Ann Intern Med</span>
|
||
2006 Feb 7;144(3):165-71.
|
||
doi: 10.7326/0003-4819-144-3-200602070-00004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16461960" target="_blank">16461960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lower%20limb%20pain%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (175)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="nl"><a target="_blank" href="/pubmed/38281015">Comparison of clinical outcomes and complications between endoscopic and minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative diseases: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Haibier A,
|
||
Yusufu A,
|
||
Hang L,
|
||
Abudurexiti T</span><br />
|
||
<span class="medgenPMjournal">J Orthop Surg Res</span>
|
||
2024 Jan 27;19(1):92.
|
||
doi: 10.1186/s13018-024-04549-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38281015" target="_blank">38281015</a><a href="/pmc/articles/PMC10821211" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35894921">Effects of Foot Orthoses on Pain and the Prevention of Lower Limb Injuries in Runners: Systematic Review and Meta-Analysis.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Pires Neves M,
|
||
Sena da Conceição C,
|
||
Lucareli PRG,
|
||
Barbosa RSDS,
|
||
Vieira JPBC,
|
||
Brasileiro AJAL,
|
||
da Silva GF,
|
||
Gomes-Neto M</span><br />
|
||
<span class="medgenPMjournal">J Sport Rehabil</span>
|
||
2022 Nov 1;31(8):1067-1074.
|
||
Epub 2022 Jul 12
|
||
doi: 10.1123/jsr.2021-0302.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35894921" target="_blank">35894921</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/34520462">Is adiposity associated with back and lower limb pain? A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Peiris WL,
|
||
Cicuttini FM,
|
||
Hussain SM,
|
||
Estee MM,
|
||
Romero L,
|
||
Ranger TA,
|
||
Fairley JL,
|
||
McLean EC,
|
||
Urquhart DM</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2021;16(9):e0256720.
|
||
Epub 2021 Sep 14
|
||
doi: 10.1371/journal.pone.0256720.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34520462" target="_blank">34520462</a><a href="/pmc/articles/PMC8439494" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34192807">Cilostazol for intermittent claudication.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Brown T,
|
||
Forster RB,
|
||
Cleanthis M,
|
||
Mikhailidis DP,
|
||
Stansby G,
|
||
Stewart M</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
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2021 Jun 30;6(6):CD003748.
|
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doi: 10.1002/14651858.CD003748.pub5.
|
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<span class="bold">PMID: </span><a href="/pubmed/34192807" target="_blank">34192807</a><a href="/pmc/articles/PMC8245159" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33951524">The Association of Spondylitis and Aortic Aneurysm Disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Patelis N,
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Nana P,
|
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Spanos K,
|
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Tasoudis P,
|
||
Brotis A,
|
||
Bisdas T,
|
||
Kouvelos G</span><br />
|
||
<span class="medgenPMjournal">Ann Vasc Surg</span>
|
||
2021 Oct;76:555-564.
|
||
Epub 2021 May 2
|
||
doi: 10.1016/j.avsg.2021.04.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33951524" target="_blank">33951524</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Lower%20limb%20pain%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (13)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22lower%20limb%20pain%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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