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<meta name="keywords" content="C0006413, bl, bl - burkitt's lymphoma, burkitt lymphoma, burkitt lymphoma, somatic, burkitt lymphoma/leukemia, burkitt tumor, burkitt's lymphoma, burkitt's lymphoma (clinical), burkitt's lymphoma - disorder, burkitt's tumor, burkitt's tumor or lymphoma, burkitt's tumour, burkitt's tumour or lymphoma, burkitt's type malignant lymphoma - small non-cleaved, burkitt's type malignant lymphoma - undifferentiated, burkitts lymphoma, burkitts tumor, familial burkitt's lymphoma, lymphoma, burkitt, lymphoma, burkitt's, malignant lymphoma, burkitt's type, malignant lymphoma, small noncleaved, burkitt's, diffuse, myc, neoplastic process, small non-cleaved cell lymphoma, small non-cleaved cell lymphoma, burkitt's type, tumor, burkitt, tumor, burkitt's, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults (Harris and Horning, 2006). It results from chromosomal translocations that involve the MYC gene (190080) and either the lambda or the kappa light chain immunoglobulin genes (147220, 147200). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=2377
|
||
ConceptID=C0006413
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Burkitt lymphoma<span class="h1sub">(BL)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2377</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0006413</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>BL; Burkitt's lymphoma; Familial Burkitt's lymphoma</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Burkitt's tumor (118617000); Burkitt's type malignant lymphoma - undifferentiated (118617000); Burkitt's lymphoma - disorder (118617000); Burkitt's type malignant lymphoma - small non-cleaved (118617000); BL - Burkitt's lymphoma (118617000); Burkitt's lymphoma (77381001); Malignant lymphoma, small noncleaved, Burkitt's, diffuse (77381001); Burkitt's tumor (77381001); Burkitt's lymphoma (clinical) (118617000); Burkitt lymphoma/leukemia (397400006); Burkitt lymphoma (77381001); Burkitt's lymphoma (118617000); Burkitt lymphoma (118617000)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_988794"><div><strong>Not genetically inherited</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>988794</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information.">CN307044</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">clinical entity without genetic inheritance.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/988794">This record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_988794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Not genetically inherited</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="MYC - ID: 4609 - NCBI Gene" href="/gene/4609" class="medgenPMinfo">MYC</a> (8q24.21)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0030080">HP:0030080</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0007243" target="_blank">MONDO:0007243</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/113970" target="_blank">113970</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=543">ORPHA543</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
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<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults (Harris and Horning, 2006). It results from chromosomal translocations that involve the MYC gene (190080) and either the lambda or the kappa light chain immunoglobulin genes (147220, 147200). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_2377"><div><strong>Burkitt lymphoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2377</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0006413</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults (Harris and Horning, 2006). It results from chromosomal translocations that involve the MYC gene (190080) and either the lambda or the kappa light chain immunoglobulin genes (147220, 147200). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/2377">Feature record</a> | <a href="/medgen?term=%22Burkitt%20lymphoma%22%5BClinical%20Features%5D%20OR%202377%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_7034"><div><strong>Immunodeficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>7034</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0021051</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Failure of the immune system to protect the body adequately from infection, due to the absence or insufficiency of some component process or substance.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/7034">Feature record</a> | <a href="/medgen?term=%22Immunodeficiency%22%5BClinical%20Features%5D%20OR%207034%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of the immune system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_7034" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency</a></span></li></ul></li><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_2377" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Burkitt lymphoma</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0006413[DISCUI]&test_type=Clinical" ref="ncbi_uid=2377">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=2377" target="_blank" href="/omim/113970">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=2377" ref="ncbi_uid=2377">V</a></span></span><span class="TLline">Burkitt lymphoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/138213" ref="tree=MeSH" title="MedGen record for Hematologic neoplasm">Hematologic neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/44223" ref="tree=MeSH" title="MedGen record for Lymphoma">Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/6160" ref="tree=MeSH" title="MedGen record for Non-Hodgkin lymphoma">Non-Hodgkin lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/277417" ref="tree=MeSH" title="MedGen record for Non-Hodgkin Lymphoma by Clinical Course">Non-Hodgkin Lymphoma by Clinical Course</a></span><ul><li><span class="TLline"><a href="/medgen/272299" ref="tree=MeSH" title="MedGen record for Aggressive Non-Hodgkin Lymphoma">Aggressive Non-Hodgkin Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/1791561" ref="tree=MeSH" title="MedGen record for Aggressive B-cell non-Hodgkin lymphoma">Aggressive B-cell non-Hodgkin lymphoma</a></span><ul><li><span class="matched_ds">Burkitt lymphoma</span><ul><li><span class="TLline"><a href="/medgen/124506" ref="tree=MeSH" title="MedGen record for Adult Burkitt Lymphoma">Adult Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/83577" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage I Adult Burkitt Lymphoma">Ann Arbor Stage I Adult Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/124703" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage II Adult Burkitt Lymphoma">Ann Arbor Stage II Adult Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/151777" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage II Contiguous Adult Burkitt Lymphoma">Ann Arbor Stage II Contiguous Adult Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/195619" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage II Non-Contiguous Adult Burkitt Lymphoma">Ann Arbor Stage II Non-Contiguous Adult Burkitt Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83610" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage III Adult Burkitt Lymphoma">Ann Arbor Stage III Adult Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/79090" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage IV Adult Burkitt Lymphoma">Ann Arbor Stage IV Adult Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/83616" ref="tree=MeSH" title="MedGen record for Recurrent Adult Burkitt Lymphoma">Recurrent Adult Burkitt Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234577" ref="tree=MeSH" title="MedGen record for Atypical Burkitt/Burkitt-Like Lymphoma">Atypical Burkitt/Burkitt-Like Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/231972" ref="tree=MeSH" title="MedGen record for Burkitt-Like Lymphoma Post-Transplant Lymphoproliferative Disorder">Burkitt-Like Lymphoma Post-Transplant Lymphoproliferative Disorder</a></span></li><li><span class="TLline"><a href="/medgen/236820" ref="tree=MeSH" title="MedGen record for Small Intestinal Atypical Burkitt/Burkitt-Like Lymphoma">Small Intestinal Atypical Burkitt/Burkitt-Like Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/267398" ref="tree=MeSH" title="MedGen record for Breast Burkitt Lymphoma">Breast Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/1640148" ref="tree=MeSH" title="MedGen record for Burkitt Lymphoma by Ann Arbor Stage">Burkitt Lymphoma by Ann Arbor Stage</a></span><ul><li><span class="TLline"><a href="/medgen/163604" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage I Burkitt Lymphoma">Ann Arbor Stage I Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/84284" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage I Childhood Burkitt Lymphoma">Ann Arbor Stage I Childhood Burkitt Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/208956" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage II Burkitt Lymphoma">Ann Arbor Stage II Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/76330" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage II Childhood Burkitt Lymphoma">Ann Arbor Stage II Childhood Burkitt Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/167768" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage III Burkitt Lymphoma">Ann Arbor Stage III Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/76331" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage III Childhood Burkitt Lymphoma">Ann Arbor Stage III Childhood Burkitt Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/167769" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage IV Burkitt Lymphoma">Ann Arbor Stage IV Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/79356" ref="tree=MeSH" title="MedGen record for Ann Arbor Stage IV Childhood Burkitt Lymphoma">Ann Arbor Stage IV Childhood Burkitt Lymphoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/231974" ref="tree=MeSH" title="MedGen record for Burkitt Lymphoma with Plasmacytoid Differentiation">Burkitt Lymphoma with Plasmacytoid Differentiation</a></span><ul><li><span class="TLline"><a href="/medgen/234468" ref="tree=MeSH" title="MedGen record for AIDS-Related Burkitt Lymphoma with Plasmacytoid Differentiation">AIDS-Related Burkitt Lymphoma with Plasmacytoid Differentiation</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/75886" ref="tree=MeSH" title="MedGen record for Childhood Burkitt Lymphoma">Childhood Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/79358" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Burkitt Lymphoma">Recurrent Childhood Burkitt Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234153" ref="tree=MeSH" title="MedGen record for Classical Burkitt Lymphoma">Classical Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/474459" ref="tree=MeSH" title="MedGen record for Colorectal Burkitt Lymphoma">Colorectal Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/272491" ref="tree=MeSH" title="MedGen record for Colon Burkitt lymphoma">Colon Burkitt lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1719114" ref="tree=MeSH" title="MedGen record for Cutaneous Burkitt Lymphoma">Cutaneous Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/232467" ref="tree=MeSH" title="MedGen record for EBV-Related Burkitt Lymphoma">EBV-Related Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/87474" ref="tree=MeSH" title="MedGen record for Endemic Burkitt Lymphoma">Endemic Burkitt Lymphoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235495" ref="tree=MeSH" title="MedGen record for Gastric Burkitt Lymphoma">Gastric Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/232640" ref="tree=MeSH" title="MedGen record for Immunodeficiency-Related Burkitt Lymphoma">Immunodeficiency-Related Burkitt Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/328361" ref="tree=MeSH" title="MedGen record for AIDS-Related Burkitt Lymphoma">AIDS-Related Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/231973" ref="tree=MeSH" title="MedGen record for Burkitt Lymphoma Post-Transplant Lymphoproliferative Disorder">Burkitt Lymphoma Post-Transplant Lymphoproliferative Disorder</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163522" ref="tree=MeSH" title="MedGen record for Recurrent Burkitt Lymphoma">Recurrent Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/208955" ref="tree=MeSH" title="MedGen record for Refractory Burkitt Lymphoma">Refractory Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/277650" ref="tree=MeSH" title="MedGen record for Small intestinal Burkitt lymphoma">Small intestinal Burkitt lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/151942" ref="tree=MeSH" title="MedGen record for Splenic Burkitt Lymphoma">Splenic Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/233464" ref="tree=MeSH" title="MedGen record for Sporadic Burkitt Lymphoma">Sporadic Burkitt Lymphoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=3747&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Burkitt lymphoma</span> in Orphanet.</div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_2377"><div><strong>Burkitt lymphoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2377</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0006413</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults (Harris and Horning, 2006). It results from chromosomal translocations that involve the MYC gene (190080) and either the lambda or the kappa light chain immunoglobulin genes (147220, 147200). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/2377">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1648396"><div><strong>Epidermodysplasia verruciformis, susceptibility to, 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648396</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4749042</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
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<div class="spaceAbove">Immunodeficiency-129 (IMD129) is an autosomal recessive immunologic disorder characterized by recurrent bacterial, viral, and fungal infections beginning in the first or second decades of life. Some affected individuals have increased susceptibility to certain human papillomaviruses (HPV), resulting in warts and skin lesions that do not respond to treatment, as well as opportunistic infections. Immunologic studies usually show decreased CD4+ T cells, increased effector memory T cells, and decreased naive T cells, suggesting a defect in T-cell development. Some individuals may also have decreased NK cells and B cells, as well as hypogammaglobulinemia. The phenotype is variable (Crequer et al., 2012; Zhou et al., 2024).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1648396">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1770239"><div><strong>X-linked lymphoproliferative disease due to SH2D1A deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1770239</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5399825</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">X-linked lymphoproliferative disease (XLP) in general is characterized by an inappropriate immune response to Epstein-Barr virus (EBV) infection leading to hemophagocytic lymphohistiocytosis (HLH) or severe mononucleosis, dysgammaglobulinemia, and lymphoproliferative disease (malignant lymphoma). The condition primarily affects males. XLP has two recognizable subtypes, XLP1 (due to pathogenic variants in SH2D1A) and XLP2 (due to pathogenic variants in XIAP). HLH / fulminant infectious mononucleosis is the most common presentation regardless of subtype. HLH is characterized as an acute illness with prolonged and high fever, bi- or trilineage cytopenias, and hepatosplenomegaly, which is often severe or fatal. Death is generally secondary to liver failure or multisystem organ dysfunction. In those with XLP1, dys- or hypogammaglobulinemia can lead to varying degrees of humoral immune dysfunction associated with bronchiectasis and recurrent respiratory infections that, if untreated, may result in death. Lymphoproliferative disease (malignant lymphoma) and other lymphoproliferative diseases are specific to XLP1 and often develop in childhood, usually following EBV exposure. Rarer findings in those with XLP1 can include aplastic anemia, vasculitis, and lymphoid granulomatosis. Males with XLP2 are more likely to have HLH without EBV infection, recurrent episodes of HLH (which is not typically seen in those with XLP1), splenomegaly, and gastrointestinal disease, including enterocolitis and perirectal abscesses or fistulae. Rarely, individuals with XLP2 and inflammatory bowel disease have been reported to develop inflammatory liver disease, which can progress to fatal liver failure. Transient hypogammaglobulinemia has been rarely observed in those with XLP2. To date, neither lymphoproliferative disease nor common variable immunodeficiency has been reported in males with XLP2. Heterozygous females rarely have symptoms. There are, however, increasing numbers of reports of affected females with unfavorable (skewed) X-chromosome inactivation favoring the X chromosome with the pathogenic variant who develop HLH, inflammatory bowel disease, and erythema nodosum.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1770239">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1824078"><div><strong>Joint contractures, osteochondromas, and B-cell lymphoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1824078</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5774305</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Joint contractures, osteochondromas, and B-cell lymphoma (JCOSL) is an autosomal recessive systemic disorder characterized by the development of painless fixed contractures of the joints in early childhood. There is evidence of abnormal chondrocyte homeostasis, resulting in contractures, osteopenia, and the development of osteochondromas. Laboratory studies show abnormal levels and function of B- and T-cell subsets, and patients can develop B-cell lymphomas or malignancies. Despite the abnormalities in immunologic cells, immunodeficiency is not a feature of the disease, suggesting that it can be classified as a 'primary immune regulatory disorder' (Sharma et al., 2022).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1824078">Condition Record</a></div></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_2377" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Burkitt lymphoma</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648396" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Epidermodysplasia verruciformis, susceptibility to, 4</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1824078" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Joint contractures, osteochondromas, and B-cell lymphoma</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1770239" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">X-linked lymphoproliferative disease due to SH2D1A deficiency</a></div></div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/33171490">The treatment of Burkitt lymphoma in adults.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Crombie J,
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LaCasce A</span><br />
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<span class="medgenPMjournal">Blood</span>
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2021 Feb 11;137(6):743-750.
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doi: 10.1182/blood.2019004099.
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<span class="bold">PMID: </span><a href="/pubmed/33171490" target="_blank">33171490</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32141616">Treatment of relapsed/refractory paediatric aggressive B-cell non-Hodgkin lymphoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Moleti ML,
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Testi AM,
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Foà R</span><br />
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<span class="medgenPMjournal">Br J Haematol</span>
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2020 Jun;189(5):826-843.
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Epub 2020 Mar 6
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doi: 10.1111/bjh.16461.
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<span class="bold">PMID: </span><a href="/pubmed/32141616" target="_blank">32141616</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/16614233">Burkitt's lymphoma: clinicopathologic features and differential diagnosis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ferry JA</span><br />
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<span class="medgenPMjournal">Oncologist</span>
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2006 Apr;11(4):375-83.
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doi: 10.1634/theoncologist.11-4-375.
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<span class="bold">PMID: </span><a href="/pubmed/16614233" target="_blank">16614233</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22burkitt%20lymphoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (139)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) B-Cell Lymphomas, 2024</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/ped_b-cell.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Pediatric Aggressive Mature B-Cell Lymphomas, 2024</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32735838">HIV-associated Burkitt lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Atallah-Yunes SA,
|
||
Murphy DJ,
|
||
Noy A</span><br />
|
||
<span class="medgenPMjournal">Lancet Haematol</span>
|
||
2020 Aug;7(8):e594-e600.
|
||
doi: 10.1016/S2352-3026(20)30126-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32735838" target="_blank">32735838</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32302884">Clinicopathological analysis of oral Burkitt's lymphoma in pediatric patients: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rodrigues-Fernandes CI,
|
||
Pérez-de-Oliveira ME,
|
||
Aristizabal Arboleda LP,
|
||
Fonseca FP,
|
||
Lopes MA,
|
||
Vargas PA,
|
||
Santos-Silva AR</span><br />
|
||
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
|
||
2020 Jul;134:110033.
|
||
Epub 2020 Apr 5
|
||
doi: 10.1016/j.ijporl.2020.110033.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32302884" target="_blank">32302884</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27888884">Update on Burkitt Lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dunleavy K,
|
||
Little RF,
|
||
Wilson WH</span><br />
|
||
<span class="medgenPMjournal">Hematol Oncol Clin North Am</span>
|
||
2016 Dec;30(6):1333-1343.
|
||
doi: 10.1016/j.hoc.2016.07.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27888884" target="_blank">27888884</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26121587">Does EBV alter the pathogenesis of malaria?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Matar CG,
|
||
Jacobs NT,
|
||
Speck SH,
|
||
Lamb TJ,
|
||
Moormann AM</span><br />
|
||
<span class="medgenPMjournal">Parasite Immunol</span>
|
||
2015 Sep;37(9):433-45.
|
||
doi: 10.1111/pim.12212.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26121587" target="_blank">26121587</a><a href="/pmc/articles/PMC10290429" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22333947">Burkitt's lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molyneux EM,
|
||
Rochford R,
|
||
Griffin B,
|
||
Newton R,
|
||
Jackson G,
|
||
Menon G,
|
||
Harrison CJ,
|
||
Israels T,
|
||
Bailey S</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2012 Mar 31;379(9822):1234-44.
|
||
Epub 2012 Feb 13
|
||
doi: 10.1016/S0140-6736(11)61177-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22333947" target="_blank">22333947</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Burkitt%20lymphoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2001)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37729460">Childhood Burkitt Lymphoma in Nigeria.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Eche-Ugwu IJ</span><br />
|
||
<span class="medgenPMjournal">Clin J Oncol Nurs</span>
|
||
2023 Sep 15;27(5):571-574.
|
||
doi: 10.1188/23.CJON.571-574.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37729460" target="_blank">37729460</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36129999">Burkitt's Lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roschewski M,
|
||
Staudt LM,
|
||
Wilson WH</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2022 Sep 22;387(12):1111-1122.
|
||
doi: 10.1056/NEJMra2025746.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36129999" target="_blank">36129999</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16614233">Burkitt's lymphoma: clinicopathologic features and differential diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ferry JA</span><br />
|
||
<span class="medgenPMjournal">Oncologist</span>
|
||
2006 Apr;11(4):375-83.
|
||
doi: 10.1634/theoncologist.11-4-375.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16614233" target="_blank">16614233</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9659515">Burkitt's lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shapira J,
|
||
Peylan-Ramu N</span><br />
|
||
<span class="medgenPMjournal">Oral Oncol</span>
|
||
1998 Jan;34(1):15-23.
|
||
doi: 10.1016/s1368-8375(97)00041-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9659515" target="_blank">9659515</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7022215">Burkitt's lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ziegler JL</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
1981 Sep 24;305(13):735-45.
|
||
doi: 10.1056/NEJM198109243051305.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7022215" target="_blank">7022215</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Burkitt%20lymphoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3155)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33171490">The treatment of Burkitt lymphoma in adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Crombie J,
|
||
LaCasce A</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2021 Feb 11;137(6):743-750.
|
||
doi: 10.1182/blood.2019004099.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33171490" target="_blank">33171490</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30418592">Comprehensive approach to diagnosis and treatment of newly diagnosed primary CNS lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grommes C,
|
||
Rubenstein JL,
|
||
DeAngelis LM,
|
||
Ferreri AJM,
|
||
Batchelor TT</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2019 Feb 19;21(3):296-305.
|
||
doi: 10.1093/neuonc/noy192.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30418592" target="_blank">30418592</a><a href="/pmc/articles/PMC6380418" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15160953">Modified magrath regimens for adults with Burkitt and Burkitt-like lymphomas: preserved efficacy with decreased toxicity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lacasce A,
|
||
Howard O,
|
||
Lib S,
|
||
Fisher D,
|
||
Weng A,
|
||
Neuberg D,
|
||
Shipp M</span><br />
|
||
<span class="medgenPMjournal">Leuk Lymphoma</span>
|
||
2004 Apr;45(4):761-7.
|
||
doi: 10.1080/1042819031000141301.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15160953" target="_blank">15160953</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7022215">Burkitt's lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ziegler JL</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
1981 Sep 24;305(13):735-45.
|
||
doi: 10.1056/NEJM198109243051305.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7022215" target="_blank">7022215</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/197352">Burkitt's lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ziegler JL</span><br />
|
||
<span class="medgenPMjournal">Med Clin North Am</span>
|
||
1977 Sep;61(5):1073-82.
|
||
doi: 10.1016/s0025-7125(16)31282-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/197352" target="_blank">197352</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Burkitt%20lymphoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1908)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31924557">Childhood cancer: Estimating regional and global incidence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Johnston WT,
|
||
Erdmann F,
|
||
Newton R,
|
||
Steliarova-Foucher E,
|
||
Schüz J,
|
||
Roman E</span><br />
|
||
<span class="medgenPMjournal">Cancer Epidemiol</span>
|
||
2021 Apr;71(Pt B):101662.
|
||
Epub 2020 Jan 8
|
||
doi: 10.1016/j.canep.2019.101662.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31924557" target="_blank">31924557</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32735838">HIV-associated Burkitt lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Atallah-Yunes SA,
|
||
Murphy DJ,
|
||
Noy A</span><br />
|
||
<span class="medgenPMjournal">Lancet Haematol</span>
|
||
2020 Aug;7(8):e594-e600.
|
||
doi: 10.1016/S2352-3026(20)30126-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32735838" target="_blank">32735838</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32453640">Multicenter Study of Risk-Adapted Therapy With Dose-Adjusted EPOCH-R in Adults With Untreated Burkitt Lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roschewski M,
|
||
Dunleavy K,
|
||
Abramson JS,
|
||
Powell BL,
|
||
Link BK,
|
||
Patel P,
|
||
Bierman PJ,
|
||
Jagadeesh D,
|
||
Mitsuyasu RT,
|
||
Peace D,
|
||
Watson PR,
|
||
Hanna WT,
|
||
Melani C,
|
||
Lucas AN,
|
||
Steinberg SM,
|
||
Pittaluga S,
|
||
Jaffe ES,
|
||
Friedberg JW,
|
||
Kahl BS,
|
||
Little RF,
|
||
Bartlett NL,
|
||
Fanale MA,
|
||
Noy A,
|
||
Wilson WH</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2020 Aug 1;38(22):2519-2529.
|
||
Epub 2020 May 26
|
||
doi: 10.1200/JCO.20.00303.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32453640" target="_blank">32453640</a><a href="/pmc/articles/PMC7392744" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28662998">Hematolymphoid lesions of the breast.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hoffmann J,
|
||
Ohgami RS</span><br />
|
||
<span class="medgenPMjournal">Semin Diagn Pathol</span>
|
||
2017 Sep;34(5):462-469.
|
||
Epub 2017 May 28
|
||
doi: 10.1053/j.semdp.2017.05.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28662998" target="_blank">28662998</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22333947">Burkitt's lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molyneux EM,
|
||
Rochford R,
|
||
Griffin B,
|
||
Newton R,
|
||
Jackson G,
|
||
Menon G,
|
||
Harrison CJ,
|
||
Israels T,
|
||
Bailey S</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2012 Mar 31;379(9822):1234-44.
|
||
Epub 2012 Feb 13
|
||
doi: 10.1016/S0140-6736(11)61177-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22333947" target="_blank">22333947</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Burkitt%20lymphoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1839)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32302884">Clinicopathological analysis of oral Burkitt's lymphoma in pediatric patients: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rodrigues-Fernandes CI,
|
||
Pérez-de-Oliveira ME,
|
||
Aristizabal Arboleda LP,
|
||
Fonseca FP,
|
||
Lopes MA,
|
||
Vargas PA,
|
||
Santos-Silva AR</span><br />
|
||
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
|
||
2020 Jul;134:110033.
|
||
Epub 2020 Apr 5
|
||
doi: 10.1016/j.ijporl.2020.110033.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32302884" target="_blank">32302884</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28662998">Hematolymphoid lesions of the breast.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hoffmann J,
|
||
Ohgami RS</span><br />
|
||
<span class="medgenPMjournal">Semin Diagn Pathol</span>
|
||
2017 Sep;34(5):462-469.
|
||
Epub 2017 May 28
|
||
doi: 10.1053/j.semdp.2017.05.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28662998" target="_blank">28662998</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25294567">The Epstein-Barr virus and the pathogenesis of lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vockerodt M,
|
||
Yap LF,
|
||
Shannon-Lowe C,
|
||
Curley H,
|
||
Wei W,
|
||
Vrzalikova K,
|
||
Murray PG</span><br />
|
||
<span class="medgenPMjournal">J Pathol</span>
|
||
2015 Jan;235(2):312-22.
|
||
doi: 10.1002/path.4459.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25294567" target="_blank">25294567</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21658615">Transformation of follicular lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lossos IS,
|
||
Gascoyne RD</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Haematol</span>
|
||
2011 Jun;24(2):147-63.
|
||
Epub 2011 May 6
|
||
doi: 10.1016/j.beha.2011.02.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21658615" target="_blank">21658615</a><a href="/pmc/articles/PMC3112479" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12074766">Burkitt's and Burkitt-like lymphoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Evens AM,
|
||
Gordon LI</span><br />
|
||
<span class="medgenPMjournal">Curr Treat Options Oncol</span>
|
||
2002 Aug;3(4):291-305.
|
||
doi: 10.1007/s11864-002-0029-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12074766" target="_blank">12074766</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Burkitt%20lymphoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1773)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/34070881">Malaria Infection and Risk for Endemic Burkitt Lymphoma: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kotepui KU,
|
||
Kotepui M</span><br />
|
||
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
|
||
2021 May 30;18(11)
|
||
doi: 10.3390/ijerph18115886.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34070881" target="_blank">34070881</a><a href="/pmc/articles/PMC8198990" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33947633">Chemotherapy Treatments for Burkitt Lymphoma: Systematic Review of Interventional Studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Della Rocca AM,
|
||
Leonart LP,
|
||
Ferreira VL,
|
||
Tonin FS,
|
||
Steffenello-Durigon G,
|
||
Del Moral JAG,
|
||
Fernandez-Llimos F,
|
||
Pontarolo R</span><br />
|
||
<span class="medgenPMjournal">Clin Lymphoma Myeloma Leuk</span>
|
||
2021 Aug;21(8):514-525.
|
||
Epub 2021 Apr 3
|
||
doi: 10.1016/j.clml.2021.03.012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33947633" target="_blank">33947633</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32144513">Burkitt and Burkitt-Like Lymphomas: a Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Saleh K,
|
||
Michot JM,
|
||
Camara-Clayette V,
|
||
Vassetsky Y,
|
||
Ribrag V</span><br />
|
||
<span class="medgenPMjournal">Curr Oncol Rep</span>
|
||
2020 Mar 6;22(4):33.
|
||
doi: 10.1007/s11912-020-0898-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32144513" target="_blank">32144513</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30897372">Rhinologic manifestations of Burkitt Lymphoma in a pediatric population: Case series and systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hong X,
|
||
Khalife S,
|
||
Bouhabel S,
|
||
Bernard C,
|
||
Daniel SJ,
|
||
Manoukian JJ,
|
||
Nguyen LHP</span><br />
|
||
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
|
||
2019 Jun;121:127-136.
|
||
Epub 2019 Mar 13
|
||
doi: 10.1016/j.ijporl.2019.03.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30897372" target="_blank">30897372</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26423805">Effect of rituximab on adult Burkitt's lymphoma: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nie M,
|
||
Wang Y,
|
||
Bi XW,
|
||
Xia Y,
|
||
Sun P,
|
||
Liu PP,
|
||
Li ZM,
|
||
Jiang WQ</span><br />
|
||
<span class="medgenPMjournal">Ann Hematol</span>
|
||
2016 Jan;95(1):19-26.
|
||
Epub 2015 Oct 1
|
||
doi: 10.1007/s00277-015-2501-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26423805" target="_blank">26423805</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Burkitt%20lymphoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (25)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_106">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0006413%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0006413%5bDISCUI%5d&filter=method%3A3%5F23" target="_blank">FISH-interphase (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0006413%5bDISCUI%5d&filter=method%3A3%5F31" target="_blank">Fluorescence in situ hybridization (FISH) (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0006413%5bDISCUI%5d&filter=method%3A3%5F32" target="_blank">Karyotyping (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0006413%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (4)</a></li>
|
||
<li><a href="/gtr/tests?term=C0006413%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (1)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0006413%5bDISCUI%5d" target="_blank">See all (10)</a></total></li>
|
||
</ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_119">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=113970" target="_blank">OMIM</a></li><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=543" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Burkitt%20lymphoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_121">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22burkitt%20lymphoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Burkitt%20lymphoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) B-Cell Lymphomas, 2024</div></li><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/ped_b-cell.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Pediatric Aggressive Mature B-Cell Lymphomas, 2024</div></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_115">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=190080" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=4609[geneid]" target="_blank">View MYC variations in ClinVar</a></li><li><a href="/nuccore/162329557" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=113970" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_116">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.diseaseinfosearch.org/Burkitt%27s+Lymphoma/997" target="_blank">Genetic Alliance</a></li><li><a href="https://www.malacards.org/card/burkitt_lymphoma" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Burkitt%20lymphoma" target="_blank">MedlinePlus</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/5973/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
</div>
|
||
</div>
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Reviews</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pubmed/clinical?term=Burkitt%20lymphoma" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed?term=Burkitt%20lymphoma%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<!-- MedGen supplemental column ends here -->
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenDiscoveryDbLinks.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=2377" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=medgen_gene_diseases&from_uid=2377" ref="log$=recordlinks">Gene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in NCBI Gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0006413[DISCUI]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0006413[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/mesh?LinkName=medgen_mesh&from_uid=2377" ref="log$=recordlinks">MeSH</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Medical Subject Headings</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&from_uid=2377" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim_gene&from_uid=2377" ref="log$=recordlinks">OMIM(Genes)</a>
|
||
<div class="brieflinkpop offscreen_noflow">OMIM records containing genes associated with phenotypes registered in MedGen</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=2377" ref="log$=recordlinks">PMC Articles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=2377" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
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<a href="https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office" class="text-white">FOIA</a><br />
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