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<meta name="keywords" content="C0002994, angioedema, angioedemas, angioneurotic edema, angioneurotic edemas, angioneurotic oedema, angiooedema, edema, angioneurotic, edema, quincke's, edemas, angioneurotic, giant urticaria, giant urticarias, pathologic function, quincke edema, quincke oedema, quincke's disease, quincke's edema, quincke's oedema, quinckes edema, quinckes oedema, urticaria, giant, urticarias, giant, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Rapid swelling (edema) of the dermis, subcutaneous tissue, mucosa and submucosal tissues of the skin of the face, normally around the mouth, and the mucosa of the mouth and/or throat, as well as the tongue during a period of minutes to several hours. The swelling can also occur elsewhere, typically in the hands. Angioedema is similar to urticaria, but the swelling is subcutaneous rather than on the epidermis." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=1543
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ConceptID=C0002994
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Angioedema</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1543</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0002994</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Angioedemas; Angioneurotic Edema; Angioneurotic Edemas; Edema, Angioneurotic; Edema, Quincke's; Edemas, Angioneurotic; Giant Urticaria; Giant Urticarias; Quincke Edema; Quincke's Edema; Quinckes Edema; Urticaria, Giant; Urticarias, Giant</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Quincke's disease (41291007); Giant urticaria (400075008); Angioedema (846575004); Angioedema (41291007); Quincke's edema (41291007); Angioneurotic edema (41291007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100665">HP:0100665</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0010481" target="_blank">MONDO:0010481</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Rapid swelling (edema) of the dermis, subcutaneous tissue, mucosa and submucosal tissues of the skin of the face, normally around the mouth, and the mucosa of the mouth and/or throat, as well as the tongue during a period of minutes to several hours. The swelling can also occur elsewhere, typically in the hands. Angioedema is similar to urticaria, but the swelling is subcutaneous rather than on the epidermis. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Angioedema</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/272632" ref="tree=MeSH" title="MedGen record for Finding by Site or System">Finding by Site or System</a></span><ul><li><span class="TLline"><a href="/medgen/224852" ref="tree=MeSH" title="MedGen record for Integumentary system finding">Integumentary system finding</a></span><ul><li><span class="matched_ds">Angioedema</span><ul><li><span class="TLline"><a href="/medgen/9229" ref="tree=MeSH" title="MedGen record for Hereditary angioneurotic edema">Hereditary angioneurotic edema</a></span><ul><li><span class="TLline"><a href="/medgen/403466" ref="tree=MeSH" title="MedGen record for Hereditary angioedema type 1">Hereditary angioedema type 1</a></span></li><li><span class="TLline"><a href="/medgen/346653" ref="tree=MeSH" title="MedGen record for Hereditary angioedema type 3">Hereditary angioedema type 3</a></span></li><li><span class="TLline"><a href="/medgen/439305" ref="tree=MeSH" title="MedGen record for Hereditary Angioedema Types I and II">Hereditary Angioedema Types I and II</a></span></li><li><span class="TLline"><a href="/medgen/1812520" ref="tree=MeSH" title="MedGen record for Hereditary angioedema with C1Inh deficiency">Hereditary angioedema with C1Inh deficiency</a></span><ul><li><span class="TLline"><a href="/medgen/585077" ref="tree=MeSH" title="MedGen record for Hereditary C1 esterase inhibitor deficiency - dysfunctional factor">Hereditary C1 esterase inhibitor deficiency - dysfunctional factor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/743231" ref="tree=MeSH" title="MedGen record for Hereditary angioedema with normal C1Inh">Hereditary angioedema with normal C1Inh</a></span><ul><li><span class="TLline"><a href="/medgen/1843147" ref="tree=MeSH" title="MedGen record for Hereditary angioedema with normal C1inh not related to F12 or PLG variant">Hereditary angioedema with normal C1inh not related to F12 or PLG variant</a></span></li><li><span class="TLline"><a href="/medgen/1843266" ref="tree=MeSH" title="MedGen record for PLG-related hereditary angioedema with normal C1inh">PLG-related hereditary angioedema with normal C1inh</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_98312"><div><strong>Anaphylotoxin inactivator deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98312</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0398782</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Carboxypeptidase-N deficiency (CPND) is an autosomal recessive disorder characterized by episodic angioedema, acute or chronic urticaria, asthma, and/or allergic hypersensitivities such as hay fever. Homozygous individuals as well as their heterozygous family members have levels of carboxypeptidase N that are below the reference range, and heterozygotes are symptomatic, albeit to a generally milder degree (Mathews et al., 1980; Vincent et al., 2024).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/98312">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_346653"><div><strong>Hereditary angioedema type 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>346653</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1857728</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary angioedema is a disorder characterized by recurrent episodes of severe swelling (angioedema). The parts of the body that are most often affected by swelling are the limbs, face, intestinal tract, and airway. Minor trauma or stress may trigger an attack, but swelling often occurs without a known trigger. Episodes involving the intestinal tract cause severe abdominal pain, nausea, and vomiting. Swelling in the airway can restrict breathing and lead to life-threatening obstruction of the airway. About one-third of people with this condition develop a non-itchy rash called erythema marginatum during an attack.\n\nSymptoms of hereditary angioedema typically begin in childhood and worsen during puberty. On average, untreated individuals have swelling episodes every 1 to 2 weeks, and most episodes last for about 3 to 4 days. The frequency and duration of attacks vary greatly among people with hereditary angioedema, even among people in the same family.\n\nHereditary angioedema is broadly divided into two types, which are distinguished by levels of a protein called C1 inhibitor (C1-INH) in the blood. These types are known as hereditary angioedema due to C1-INH deficiency and hereditary angioedema with normal C1-INH. \n\nHereditary angioedema due to C1-INH deficiency is further divided into two types: type I occurs when C1-INH levels are low, and type II occurs when the C1-INH protein is not functioning correctly. \n\n\n\nThe different types of hereditary angioedema have similar signs and symptoms. </div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/346653">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_403466"><div><strong>Hereditary angioedema type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>403466</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2717906</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A form of hereditary angioedema characterized by acute edema in subcutaneous tissues, viscera and/or the upper airway.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/403466">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_482544"><div><strong>Familial cold autoinflammatory syndrome 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>482544</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3280914</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial cold autoinflammatory syndrome-3 is an autosomal dominant immune disorder characterized by the development of cutaneous urticaria, erythema, and pruritus in response to cold exposure. Affected individuals have variable additional immunologic defects, including antibody deficiency, decreased numbers of B cells, defective B cells, increased susceptibility to infection, and increased risk of autoimmune disorders (summary by Ombrello et al., 2012). For a discussion of genetic heterogeneity of FCAS, see FCAS1 (120100).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/482544">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_813041"><div><strong>Susceptibility to angioedema induced by ACE inhibitors</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>813041</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3806711</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Approximately 40 million people take ACE inhibitors (ACEi) to treat hypertension and cardiovascular disease. A small proportion of white patients who take ACEi (0.1-0.7%) develop angioedema (AEACEI) (Israili and Hall, 1992; Vleeming et al., 1998), a potentially life-threatening side effect characterized by swelling of the face, lips, tongue, and airway that can lead to suffocation and death if severe. ACEi-associated angioedema is 4 to 5 times more prevalent among African Americans (Brown et al., 1996; Coats, 2002). Other risk factors include female sex, smoking, immunosuppressant therapy, and seasonal allergies. The pathophysiology of ACEi-associated angioedema is thought to be related to increased circulating bradykinin, which is normally degraded by ACE. During pharmacologic ACE inhibition, bradykinin is primarily degraded by aminopeptidase P (summary by Duan et al., 2005 and Woodard-Grice et al., 2010). Aminopeptidase P is encoded by 3 genes: XPNPEP1 (602443) on chromosome 10q25, XPNPEP2 (300145) on chromosome Xq25, and XPNPEP3 (613553) on chromosome 22q13.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/813041">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1787336"><div><strong>Angioedema, hereditary, 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1787336</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543503</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary angioedema-4 (HAE4) is an autosomal dominant disorder characterized by episodic subcutaneous or submucosal edema with onset usually in adulthood. Swelling most commonly involves the face and tongue, sometimes resulting in occlusion of the airway, which can cause death. The larynx, abdomen, and limbs may also be involved. Circulating C1 inhibitor (C1INH) levels and function, as well as plasminogen levels and activity, are normal. Although the disorder is autosomal dominant, there is evidence of incomplete penetrance, variable expressivity, and female predominance. The episodes may be triggered by stress, oral contraceptives, ACE inhibitors, and angiotensin II receptor blockades. The pathogenesis is believed to be due to altered plasmin function resulting in enhanced release of bradykinin. Successful clinical management has been achieved with tranexamic acid, which inhibits plasmin, and icatibant, a selective bradykinin B2 receptor (113503) antagonist (summary by Farkas et al., 2021). For a discussion of genetic heterogeneity of HAE, see 106100.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1787336">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1780904"><div><strong>Angioedema, hereditary, 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1780904</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543508</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary angioedema-5 (HAE5) is an autosomal dominant disorder characterized by localized and self-limiting edema of the subcutaneous or submucosal tissue due to an episodic increase in vascular permeability. Affected individuals have onset of episodic swelling of the face, lips, hands, and abdomen in the second decade of life. Treatment with tranexamic acid may be effective in reducing the severity and frequency of the attacks (summary by Bafunno et al., 2018). For a discussion of genetic heterogeneity of hereditary angioedema, see 106100.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1780904">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1785484"><div><strong>Angioedema, hereditary, 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1785484</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543516</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary angioedema-6 (HAE6) is an autosomal dominant disorder characterized by onset of episodic subcutaneous and submucosal swelling in adulthood. The face, mouth, and tongue are often affected; some patients have distal limb or abdominal edema. Levels of complement component inhibitor (C1INH; 606860) are normal (summary by Bork et al., 2019). For a discussion of genetic heterogeneity of HAE, see 106100.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1785484">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1784046"><div><strong>Angioedema, hereditary, 7</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1784046</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543526</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary angioedema-7 (HAE7) is an autosomal dominant disorder characterized by onset of recurrent episodic swelling of the face, lips, and oral mucosa in the second decade. The disorder is due to abnormal vascular permeability (summary by Ariano et al., 2020). For a discussion of genetic heterogeneity of HAE, see 106100.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1784046">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1780930"><div><strong>Angioedema, hereditary, 8</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1780930</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543528</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary angioedema-8 (HAE8) is an autosomal dominant disorder characterized clinically by recurrent and self-limited episodes of localized edema in various organs, including the face, tongue, larynx, and extremities. In rare cases, swelling of the tongue or larynx can lead to airway obstruction. Abdominal attacks may also occur, resulting in abdominal pain, vomiting, and diarrhea. The disorder results from enhanced vascular permeability (summary by Bork et al., 2021). For a discussion of genetic heterogeneity of HAE, see 106100.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1780930">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1802991"><div><strong>Netherton syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1802991</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5574950</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Netherton syndrome (NETH) is a rare and severe autosomal recessive skin disorder characterized by congenital erythroderma, a specific hair-shaft abnormality, and atopic manifestations with high IgE levels. Generalized scaly erythroderma is apparent at or soon after birth and usually persists. Scalp hair is sparse and brittle with a characteristic 'bamboo' shape under light microscopic examination due to invagination of the distal part of the hair shaft to its proximal part. Atopic manifestations include eczema-like rashes, atopic dermatitis, pruritus, hay fever, angioedema, urticaria, high levels of IgE in the serum, and hypereosinophilia. Life-threatening complications are frequent during the neonatal period, including hypernatremic dehydration, hypothermia, extreme weight loss, bronchopneumonia, and sepsis. During childhood, failure to thrive is common as a result of malnutrition, metabolic disorders, chronic erythroderma, persistent cutaneous infections, or enteropathy (summary by Bitoun et al., 2002).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1802991">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98312" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Anaphylotoxin inactivator deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1787336" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Angioedema, hereditary, 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1780904" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Angioedema, hereditary, 5</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1785484" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Angioedema, hereditary, 6</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1784046" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Angioedema, hereditary, 7</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (11)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1780930" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Angioedema, hereditary, 8</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_482544" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial cold autoinflammatory syndrome 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_403466" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary angioedema type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_346653" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary angioedema type 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1802991" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Netherton syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_813041" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Susceptibility to angioedema induced by ACE inhibitors</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35006617">The international WAO/EAACI guideline for the management of hereditary angioedema-The 2021 revision and update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maurer M,
|
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Magerl M,
|
||
Betschel S,
|
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Aberer W,
|
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Ansotegui IJ,
|
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Aygören-Pürsün E,
|
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Banerji A,
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Bara NA,
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Boccon-Gibod I,
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Bork K,
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Bouillet L,
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Boysen HB,
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Brodszki N,
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Busse PJ,
|
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Bygum A,
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Caballero T,
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Cancian M,
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Castaldo A,
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Cohn DM,
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Csuka D,
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Farkas H,
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Gompels M,
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Gower R,
|
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Grumach AS,
|
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Guidos-Fogelbach G,
|
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Hide M,
|
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Kang HR,
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Kaplan AP,
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Katelaris C,
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Kiani-Alikhan S,
|
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Lei WT,
|
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Lockey R,
|
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Longhurst H,
|
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Lumry WR,
|
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MacGinnitie A,
|
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Malbran A,
|
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Martinez Saguer I,
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Matta JJ,
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Nast A,
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Nguyen D,
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Nieto-Martinez SA,
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Pawankar R,
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Peter J,
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Porebski G,
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Prior N,
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Reshef A,
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Riedl M,
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Ritchie B,
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Rafique Sheikh F,
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Smith WB,
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Spaeth PJ,
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Stobiecki M,
|
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Toubi E,
|
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Varga LA,
|
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Weller K,
|
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Zanichelli A,
|
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Zhi Y,
|
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Zuraw B,
|
||
Craig T</span><br />
|
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<span class="medgenPMjournal">Allergy</span>
|
||
2022 Jul;77(7):1961-1990.
|
||
Epub 2022 Feb 3
|
||
doi: 10.1111/all.15214.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35006617" target="_blank">35006617</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34536239">The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zuberbier T,
|
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Abdul Latiff AH,
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Abuzakouk M,
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Aquilina S,
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Asero R,
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Baker D,
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Ballmer-Weber B,
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Bangert C,
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Ben-Shoshan M,
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Bernstein JA,
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Bindslev-Jensen C,
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Brockow K,
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Brzoza Z,
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Chong Neto HJ,
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Church MK,
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Criado PR,
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Danilycheva IV,
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Dressler C,
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Ensina LF,
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Hébert J,
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Hide M,
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Kaplan A,
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Kapp A,
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Kessel A,
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Kocatürk E,
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Kulthanan K,
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Larenas-Linnemann D,
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Lauerma A,
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Leslie TA,
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Magerl M,
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Makris M,
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Meshkova RY,
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Metz M,
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Micallef D,
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Mortz CG,
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Nast A,
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Oude-Elberink H,
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Pawankar R,
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Pigatto PD,
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Ratti Sisa H,
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Rojo Gutiérrez MI,
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Saini SS,
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Schmid-Grendelmeier P,
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Sekerel BE,
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Siebenhaar F,
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Siiskonen H,
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Soria A,
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Thomsen SF,
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Vestergaard C,
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Maurer M</span><br />
|
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<span class="medgenPMjournal">Allergy</span>
|
||
2022 Mar;77(3):734-766.
|
||
Epub 2021 Oct 20
|
||
doi: 10.1111/all.15090.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34536239" target="_blank">34536239</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34264448">Contact Dermatitis: Classifications and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li Y,
|
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Li L</span><br />
|
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<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
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2021 Dec;61(3):245-281.
|
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Epub 2021 Jul 15
|
||
doi: 10.1007/s12016-021-08875-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34264448" target="_blank">34264448</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22angioedema%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (567)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38937016">Current and Emerging Therapeutics in Hereditary Angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Do T,
|
||
Riedl MA</span><br />
|
||
<span class="medgenPMjournal">Immunol Allergy Clin North Am</span>
|
||
2024 Aug;44(3):561-576.
|
||
Epub 2024 Apr 21
|
||
doi: 10.1016/j.iac.2024.03.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38937016" target="_blank">38937016</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35364476">Tranexamic acid - A narrative review for the emergency medicine clinician.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang K,
|
||
Santiago R</span><br />
|
||
<span class="medgenPMjournal">Am J Emerg Med</span>
|
||
2022 Jun;56:33-44.
|
||
Epub 2022 Mar 22
|
||
doi: 10.1016/j.ajem.2022.03.027.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35364476" target="_blank">35364476</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34001550">Angiotensin-converting-enzyme inhibitor-induced angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Quickfall D,
|
||
Jakubovic B,
|
||
Zipursky JS</span><br />
|
||
<span class="medgenPMjournal">CMAJ</span>
|
||
2021 May 17;193(20):E735.
|
||
doi: 10.1503/cmaj.202308.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34001550" target="_blank">34001550</a><a href="/pmc/articles/PMC8177945" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32298850">Urticaria and Angioedema Across the Ages.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Saini S,
|
||
Shams M,
|
||
Bernstein JA,
|
||
Maurer M</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2020 Jun;8(6):1866-1874.
|
||
Epub 2020 Apr 13
|
||
doi: 10.1016/j.jaip.2020.03.030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32298850" target="_blank">32298850</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29884969">ACE Inhibitor-Induced Angioedema: a Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kostis WJ,
|
||
Shetty M,
|
||
Chowdhury YS,
|
||
Kostis JB</span><br />
|
||
<span class="medgenPMjournal">Curr Hypertens Rep</span>
|
||
2018 Jun 8;20(7):55.
|
||
doi: 10.1007/s11906-018-0859-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29884969" target="_blank">29884969</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angioedema%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2050)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38937018">Urticaria and Angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stitt J</span><br />
|
||
<span class="medgenPMjournal">Immunol Allergy Clin North Am</span>
|
||
2024 Aug;44(3):xv-xvi.
|
||
Epub 2024 May 13
|
||
doi: 10.1016/j.iac.2024.04.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38937018" target="_blank">38937018</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38937017">Urticaria and Angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Katial R</span><br />
|
||
<span class="medgenPMjournal">Immunol Allergy Clin North Am</span>
|
||
2024 Aug;44(3):xiii-xiv.
|
||
Epub 2024 May 13
|
||
doi: 10.1016/j.iac.2024.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38937017" target="_blank">38937017</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37105604">Urticaria and Angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Szymanski K,
|
||
Schaefer P</span><br />
|
||
<span class="medgenPMjournal">Prim Care</span>
|
||
2023 Jun;50(2):237-252.
|
||
Epub 2023 Mar 2
|
||
doi: 10.1016/j.pop.2022.11.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37105604" target="_blank">37105604</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32298850">Urticaria and Angioedema Across the Ages.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Saini S,
|
||
Shams M,
|
||
Bernstein JA,
|
||
Maurer M</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2020 Jun;8(6):1866-1874.
|
||
Epub 2020 Apr 13
|
||
doi: 10.1016/j.jaip.2020.03.030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32298850" target="_blank">32298850</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31310036">Angioedema Masqueraders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fok JS,
|
||
Katelaris CH</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Allergy</span>
|
||
2019 Oct;49(10):1274-1282.
|
||
Epub 2019 Aug 6
|
||
doi: 10.1111/cea.13463.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31310036" target="_blank">31310036</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angioedema%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3115)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38294975">CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Longhurst HJ,
|
||
Lindsay K,
|
||
Petersen RS,
|
||
Fijen LM,
|
||
Gurugama P,
|
||
Maag D,
|
||
Butler JS,
|
||
Shah MY,
|
||
Golden A,
|
||
Xu Y,
|
||
Boiselle C,
|
||
Vogel JD,
|
||
Abdelhady AM,
|
||
Maitland ML,
|
||
McKee MD,
|
||
Seitzer J,
|
||
Han BW,
|
||
Soukamneuth S,
|
||
Leonard J,
|
||
Sepp-Lorenzino L,
|
||
Clark ED,
|
||
Lebwohl D,
|
||
Cohn DM</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2024 Feb 1;390(5):432-441.
|
||
doi: 10.1056/NEJMoa2309149.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38294975" target="_blank">38294975</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34182274">Unilateral angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee JE,
|
||
Bryant SM</span><br />
|
||
<span class="medgenPMjournal">Am J Emerg Med</span>
|
||
2021 Nov;49:302-303.
|
||
Epub 2021 Jun 24
|
||
doi: 10.1016/j.ajem.2021.06.040.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34182274" target="_blank">34182274</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31511276">Quincke's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chandran A,
|
||
Sakthivel P,
|
||
Chirom AS</span><br />
|
||
<span class="medgenPMjournal">BMJ Case Rep</span>
|
||
2019 Sep 11;12(9)
|
||
doi: 10.1136/bcr-2019-231967.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31511276" target="_blank">31511276</a><a href="/pmc/articles/PMC6738731" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31347612">Lanadelumab to treat hereditary angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wedi B</span><br />
|
||
<span class="medgenPMjournal">Drugs Today (Barc)</span>
|
||
2019 Jul;55(7):439-448.
|
||
doi: 10.1358/dot.2019.55.7.2985293.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31347612" target="_blank">31347612</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27886913">Biologics in Chronic Urticaria.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bulkhi A,
|
||
Cooke AJ,
|
||
Casale TB</span><br />
|
||
<span class="medgenPMjournal">Immunol Allergy Clin North Am</span>
|
||
2017 Feb;37(1):95-112.
|
||
Epub 2016 Oct 28
|
||
doi: 10.1016/j.iac.2016.08.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27886913" target="_blank">27886913</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angioedema%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3899)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31475794">Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Solomon SD,
|
||
McMurray JJV,
|
||
Anand IS,
|
||
Ge J,
|
||
Lam CSP,
|
||
Maggioni AP,
|
||
Martinez F,
|
||
Packer M,
|
||
Pfeffer MA,
|
||
Pieske B,
|
||
Redfield MM,
|
||
Rouleau JL,
|
||
van Veldhuisen DJ,
|
||
Zannad F,
|
||
Zile MR,
|
||
Desai AS,
|
||
Claggett B,
|
||
Jhund PS,
|
||
Boytsov SA,
|
||
Comin-Colet J,
|
||
Cleland J,
|
||
Düngen HD,
|
||
Goncalvesova E,
|
||
Katova T,
|
||
Kerr Saraiva JF,
|
||
Lelonek M,
|
||
Merkely B,
|
||
Senni M,
|
||
Shah SJ,
|
||
Zhou J,
|
||
Rizkala AR,
|
||
Gong J,
|
||
Shi VC,
|
||
Lefkowitz MP;
|
||
PARAGON-HF Investigators and Committees</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2019 Oct 24;381(17):1609-1620.
|
||
Epub 2019 Sep 1
|
||
doi: 10.1056/NEJMoa1908655.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31475794" target="_blank">31475794</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30241623">Urticaria: A comprehensive review: Epidemiology, diagnosis, and work-up.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Antia C,
|
||
Baquerizo K,
|
||
Korman A,
|
||
Bernstein JA,
|
||
Alikhan A</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2018 Oct;79(4):599-614.
|
||
doi: 10.1016/j.jaad.2018.01.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30241623" target="_blank">30241623</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27545736">Anaphylaxis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hernandez L,
|
||
Papalia S,
|
||
Pujalte GG</span><br />
|
||
<span class="medgenPMjournal">Prim Care</span>
|
||
2016 Sep;43(3):477-85.
|
||
doi: 10.1016/j.pop.2016.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27545736" target="_blank">27545736</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9654948">Urticaria.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weston WL,
|
||
Badgett JT</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
1998 Jul;19(7):240-4.
|
||
doi: 10.1542/pir.19-7-240.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9654948" target="_blank">9654948</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4122980">Hereditary angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gigli I</span><br />
|
||
<span class="medgenPMjournal">J Invest Dermatol</span>
|
||
1973 Jun;60(6):516-21.
|
||
doi: 10.1111/1523-1747.ep12703581.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4122980" target="_blank">4122980</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angioedema%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (956)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38819395">Efficacy and Safety of Donidalorsen for Hereditary Angioedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Riedl MA,
|
||
Tachdjian R,
|
||
Lumry WR,
|
||
Craig T,
|
||
Karakaya G,
|
||
Gelincik A,
|
||
Stobiecki M,
|
||
Jacobs JS,
|
||
Gokmen NM,
|
||
Reshef A,
|
||
Gompels MM,
|
||
Manning ME,
|
||
Bordone L,
|
||
Newman KB,
|
||
Treadwell S,
|
||
Wang S,
|
||
Yarlas A,
|
||
Cohn DM;
|
||
OASIS-HAE Team</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2024 Jul 4;391(1):21-31.
|
||
Epub 2024 May 31
|
||
doi: 10.1056/NEJMoa2402478.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38819395" target="_blank">38819395</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30328786">Angioedema: a rare and sometimes delayed side effect of angiotensin-converting enzyme inhibitors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Davin L,
|
||
Marechal P,
|
||
Lancellotti P,
|
||
Martinez C,
|
||
Pierard L,
|
||
Radermecker R</span><br />
|
||
<span class="medgenPMjournal">Acta Cardiol</span>
|
||
2019 Aug;74(4):277-281.
|
||
Epub 2018 Oct 17
|
||
doi: 10.1080/00015385.2018.1507477.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30328786" target="_blank">30328786</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28543019">The burden of chronic spontaneous urticaria is substantial: Real-world evidence from ASSURE-CSU.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maurer M,
|
||
Abuzakouk M,
|
||
Bérard F,
|
||
Canonica W,
|
||
Oude Elberink H,
|
||
Giménez-Arnau A,
|
||
Grattan C,
|
||
Hollis K,
|
||
Knulst A,
|
||
Lacour JP,
|
||
Lynde C,
|
||
Marsland A,
|
||
McBride D,
|
||
Nakonechna A,
|
||
Ortiz de Frutos J,
|
||
Proctor C,
|
||
Sussman G,
|
||
Sweeney C,
|
||
Tian H,
|
||
Weller K,
|
||
Wolin D,
|
||
Balp MM</span><br />
|
||
<span class="medgenPMjournal">Allergy</span>
|
||
2017 Dec;72(12):2005-2016.
|
||
Epub 2017 Jul 10
|
||
doi: 10.1111/all.13209.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28543019" target="_blank">28543019</a><a href="/pmc/articles/PMC5724512" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28455343">2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yancy CW,
|
||
Jessup M,
|
||
Bozkurt B,
|
||
Butler J,
|
||
Casey DE Jr,
|
||
Colvin MM,
|
||
Drazner MH,
|
||
Filippatos GS,
|
||
Fonarow GC,
|
||
Givertz MM,
|
||
Hollenberg SM,
|
||
Lindenfeld J,
|
||
Masoudi FA,
|
||
McBride PE,
|
||
Peterson PN,
|
||
Stevenson LW,
|
||
Westlake C</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2017 Aug 8;136(6):e137-e161.
|
||
Epub 2017 Apr 28
|
||
doi: 10.1161/CIR.0000000000000509.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28455343" target="_blank">28455343</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27585061">Diagnostic utility of challenge procedures for physical urticaria/angioedema syndromes: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cuervo-Pardo L,
|
||
Gonzalez-Estrada A,
|
||
Lang DM</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Allergy Clin Immunol</span>
|
||
2016 Oct;16(5):511-5.
|
||
doi: 10.1097/ACI.0000000000000298.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27585061" target="_blank">27585061</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angioedema%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1344)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/36326435">Interventions for the long-term prevention of hereditary angioedema attacks.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Beard N,
|
||
Frese M,
|
||
Smertina E,
|
||
Mere P,
|
||
Katelaris C,
|
||
Mills K</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2022 Nov 3;11(11):CD013403.
|
||
doi: 10.1002/14651858.CD013403.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36326435" target="_blank">36326435</a><a href="/pmc/articles/PMC9632406" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35217468">Adverse drug reactions of GLP-1 agonists: A systematic review of case reports.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shetty R,
|
||
Basheer FT,
|
||
Poojari PG,
|
||
Thunga G,
|
||
Chandran VP,
|
||
Acharya LD</span><br />
|
||
<span class="medgenPMjournal">Diabetes Metab Syndr</span>
|
||
2022 Mar;16(3):102427.
|
||
Epub 2022 Feb 12
|
||
doi: 10.1016/j.dsx.2022.102427.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35217468" target="_blank">35217468</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33653974">Critical Care Management of the Patient With Anaphylaxis: A Concise Definitive Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krishnaswamy G</span><br />
|
||
<span class="medgenPMjournal">Crit Care Med</span>
|
||
2021 May 1;49(5):838-857.
|
||
doi: 10.1097/CCM.0000000000004893.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33653974" target="_blank">33653974</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31555262">Systematic Review of Safety and Efficacy of Rituximab in Treating Immune-Mediated Disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kaegi C,
|
||
Wuest B,
|
||
Schreiner J,
|
||
Steiner UC,
|
||
Vultaggio A,
|
||
Matucci A,
|
||
Crowley C,
|
||
Boyman O</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2019;10:1990.
|
||
Epub 2019 Sep 6
|
||
doi: 10.3389/fimmu.2019.01990.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31555262" target="_blank">31555262</a><a href="/pmc/articles/PMC6743223" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31030987">Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chu DK,
|
||
Wood RA,
|
||
French S,
|
||
Fiocchi A,
|
||
Jordana M,
|
||
Waserman S,
|
||
Brożek JL,
|
||
Schünemann HJ</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2019 Jun 1;393(10187):2222-2232.
|
||
Epub 2019 Apr 25
|
||
doi: 10.1016/S0140-6736(19)30420-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31030987" target="_blank">31030987</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angioedema%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (86)</a></div></div>
|
||
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|
||
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|
||
|
||
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|
||
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|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Angioedema" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22angioedema%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Angioedema%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Angioedema" target="_blank">MedlinePlus</a></li></ul></div>
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<a href="/pubmed?term=Angioedema%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67ce8b96a68b6b5afc2fa9a8">Angioedema</a>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67ce8b94a68b6b5afc2f9860">C3151087[trait identifier] AND "Centre for Mendelian Genomics, Un... <span class="number">(3)</span></a>
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<div class="ralinkpop offscreen_noflow">C3151087[trait identifier] AND "Centre for Mendelian Genomics, University Medical Centre Ljubljana"[submitter]<div class="brieflinkpopdesc">Search</div></div>
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