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1040 lines
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<meta name="keywords" content="C0409959, degenerative joint disease of knee, disease or syndrome, gonarthrosis, knee djd (degenerative joint disease), knee osteoarthritides, knee osteoarthritis, oa - osteoarthritis of knee, os6, osteoarthritis of knee, osteoarthritis of the knee, osteoarthritis susceptibility 6, osteoarthritis, knee, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)" /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=98371
|
||
ConceptID=C0409959
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Osteoarthritis, knee<span class="h1sub">(OS6)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98371</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0409959</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Osteoarthritis of knee</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Degenerative joint disease of knee (239873007); Gonarthrosis (239873007); Knee DJD (degenerative joint disease) (239873007); Osteoarthritis of knee (239873007); OA - Osteoarthritis of knee (239873007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0005086">HP:0005086</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0005416" target="_blank">MONDO:0005416</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/612401" target="_blank">612401</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019) [from <a title="Monarch Initiative" href="https://monarchinitiative.org/" class="defSource" target="_blank">MONDO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=98371" target="_blank" href="/omim/612401">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Osteoarthritis, knee</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/536898" ref="tree=MeSH" title="MedGen record for Abnormality of limbs">Abnormality of limbs</a></span><ul><li><span class="TLline"><a href="/medgen/242750" ref="tree=MeSH" title="MedGen record for Abnormality of the lower limb">Abnormality of the lower limb</a></span><ul><li><span class="TLline"><a href="/medgen/866624" ref="tree=MeSH" title="MedGen record for Abnormality of lower limb joint">Abnormality of lower limb joint</a></span><ul><li><span class="TLline"><a href="/medgen/871199" ref="tree=MeSH" title="MedGen record for Abnormality of the knee">Abnormality of the knee</a></span><ul><li><span class="TLline"><a href="/medgen/1841978" ref="tree=MeSH" title="MedGen record for Abnormal knee morphology">Abnormal knee morphology</a></span><ul><li><span class="matched_ds">Osteoarthritis, knee</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_82694"><div><strong>Marshall syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82694</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265235</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Marshall syndrome (MRSHS) is characterized by midfacial hypoplasia, cleft palate, ocular anomalies including high myopia and cataracts, sensorineural hearing loss, short stature with spondyloepiphyseal dysplasia, and arthropathy. In contrast to Stickler syndrome type II, it has less severe eye findings but striking ocular hypertelorism, more pronounced maxillary hypoplasia, and ectodermal abnormalities (summary by Shanske et al., 1997 and Ala-Kokko and Shanske, 2009).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82694">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_609409"><div><strong>Namaqualand hip dysplasia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>609409</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432214</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Mild spondyloepiphyseal dysplasia due to COL2A1 mutation with early-onset osteoarthritis is a type 2 collagen-related bone disorder characterized by precocious, generalized osteoarthritis (with onset as early as childhood) and mild, dysplastic spinal changes (flattening of vertebrae, irregular endplates and wedge-shaped deformities) resulting in a mildly short trunk.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/609409">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_333092"><div><strong>Epiphyseal dysplasia, multiple, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>333092</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1838429</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal dominant multiple epiphyseal dysplasia (MED) presents in early childhood, usually with pain in the hips and/or knees after exercise. Affected children report fatigue with long-distance walking. Waddling gait may be present. Adult height is either in the lower range of normal or mildly shortened. The limbs are relatively short in comparison to the trunk. Pain and joint deformity progress, resulting in early-onset osteoarthritis, particularly of the large weight-bearing joints.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/333092">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462437"><div><strong>Aneurysm-osteoarthritis syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462437</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151087</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462437">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1794251"><div><strong>Loeys-Dietz syndrome 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794251</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5562041</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1794251">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462437" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Aneurysm-osteoarthritis syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_333092" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Epiphyseal dysplasia, multiple, 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794251" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Loeys-Dietz syndrome 6</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_82694" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Marshall syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_609409" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Namaqualand hip dysplasia</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33560326">Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Katz JN,
|
||
Arant KR,
|
||
Loeser RF</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2021 Feb 9;325(6):568-578.
|
||
doi: 10.1001/jama.2020.22171.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33560326" target="_blank">33560326</a><a href="/pmc/articles/PMC8225295" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31431274">Evidence-based recommendations for the management of anterior cruciate ligament (ACL) rupture.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Filbay SR,
|
||
Grindem H</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Rheumatol</span>
|
||
2019 Feb;33(1):33-47.
|
||
Epub 2019 Feb 21
|
||
doi: 10.1016/j.berh.2019.01.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31431274" target="_blank">31431274</a><a href="/pmc/articles/PMC6723618" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30919810">Non-surgical treatment of knee osteoarthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kan HS,
|
||
Chan PK,
|
||
Chiu KY,
|
||
Yan CH,
|
||
Yeung SS,
|
||
Ng YL,
|
||
Shiu KW,
|
||
Ho T</span><br />
|
||
<span class="medgenPMjournal">Hong Kong Med J</span>
|
||
2019 Apr;25(2):127-133.
|
||
Epub 2019 Mar 28
|
||
doi: 10.12809/hkmj187600.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30919810" target="_blank">30919810</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22osteoarthritis%2C%20knee%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (953)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng226" target="_blank">UK NICE Guideline NG226, Osteoarthritis in over 16s: diagnosis and management, 2022</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39250809">Knee Osteoarthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gelber AC</span><br />
|
||
<span class="medgenPMjournal">Ann Intern Med</span>
|
||
2024 Sep;177(9):ITC129-ITC144.
|
||
Epub 2024 Sep 10
|
||
doi: 10.7326/ANNALS-24-01249.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39250809" target="_blank">39250809</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34465902">Early-stage symptomatic osteoarthritis of the knee - time for action.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mahmoudian A,
|
||
Lohmander LS,
|
||
Mobasheri A,
|
||
Englund M,
|
||
Luyten FP</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Rheumatol</span>
|
||
2021 Oct;17(10):621-632.
|
||
Epub 2021 Aug 31
|
||
doi: 10.1038/s41584-021-00673-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34465902" target="_blank">34465902</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29035179">Knee Osteoarthritis: A Primer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lespasio MJ,
|
||
Piuzzi NS,
|
||
Husni ME,
|
||
Muschler GF,
|
||
Guarino A,
|
||
Mont MA</span><br />
|
||
<span class="medgenPMjournal">Perm J</span>
|
||
2017;21:16-183.
|
||
doi: 10.7812/TPP/16-183.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29035179" target="_blank">29035179</a><a href="/pmc/articles/PMC5638628" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27330013">Knee osteoarthritis: a review of management options.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hussain SM,
|
||
Neilly DW,
|
||
Baliga S,
|
||
Patil S,
|
||
Meek R</span><br />
|
||
<span class="medgenPMjournal">Scott Med J</span>
|
||
2016 Feb;61(1):7-16.
|
||
Epub 2016 Jun 21
|
||
doi: 10.1177/0036933015619588.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27330013" target="_blank">27330013</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20305774">The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Michael JW,
|
||
Schlüter-Brust KU,
|
||
Eysel P</span><br />
|
||
<span class="medgenPMjournal">Dtsch Arztebl Int</span>
|
||
2010 Mar;107(9):152-62.
|
||
Epub 2010 Mar 5
|
||
doi: 10.3238/arztebl.2010.0152.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20305774" target="_blank">20305774</a><a href="/pmc/articles/PMC2841860" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteoarthritis%2C%20knee%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17428)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34600121">How does hip osteoarthritis differ from knee osteoarthritis?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hall M,
|
||
van der Esch M,
|
||
Hinman RS,
|
||
Peat G,
|
||
de Zwart A,
|
||
Quicke JG,
|
||
Runhaar J,
|
||
Knoop J,
|
||
van der Leeden M,
|
||
de Rooij M,
|
||
Meulenbelt I,
|
||
Vliet Vlieland T,
|
||
Lems WF,
|
||
Holden MA,
|
||
Foster NE,
|
||
Bennell KL</span><br />
|
||
<span class="medgenPMjournal">Osteoarthritis Cartilage</span>
|
||
2022 Jan;30(1):32-41.
|
||
Epub 2021 Sep 29
|
||
doi: 10.1016/j.joca.2021.09.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34600121" target="_blank">34600121</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33807695">Recent Updates of Diagnosis, Pathophysiology, and Treatment on Osteoarthritis of the Knee.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jang S,
|
||
Lee K,
|
||
Ju JH</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2021 Mar 5;22(5)
|
||
doi: 10.3390/ijms22052619.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33807695" target="_blank">33807695</a><a href="/pmc/articles/PMC7961389" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33406330">Osteoarthritis of the Knee.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sharma L</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2021 Jan 7;384(1):51-59.
|
||
doi: 10.1056/NEJMcp1903768.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33406330" target="_blank">33406330</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29035179">Knee Osteoarthritis: A Primer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lespasio MJ,
|
||
Piuzzi NS,
|
||
Husni ME,
|
||
Muschler GF,
|
||
Guarino A,
|
||
Mont MA</span><br />
|
||
<span class="medgenPMjournal">Perm J</span>
|
||
2017;21:16-183.
|
||
doi: 10.7812/TPP/16-183.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29035179" target="_blank">29035179</a><a href="/pmc/articles/PMC5638628" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20305774">The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Michael JW,
|
||
Schlüter-Brust KU,
|
||
Eysel P</span><br />
|
||
<span class="medgenPMjournal">Dtsch Arztebl Int</span>
|
||
2010 Mar;107(9):152-62.
|
||
Epub 2010 Mar 5
|
||
doi: 10.3238/arztebl.2010.0152.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20305774" target="_blank">20305774</a><a href="/pmc/articles/PMC2841860" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteoarthritis%2C%20knee%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6213)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33846757">Effectiveness of total knee arthroplasty rehabilitation programmes: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alrawashdeh W,
|
||
Eschweiler J,
|
||
Migliorini F,
|
||
El Mansy Y,
|
||
Tingart M,
|
||
Rath B</span><br />
|
||
<span class="medgenPMjournal">J Rehabil Med</span>
|
||
2021 Jun 2;53(6):jrm00200.
|
||
doi: 10.2340/16501977-2827.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33846757" target="_blank">33846757</a><a href="/pmc/articles/PMC8814866" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33666347">Effects of exercise on knee osteoarthritis: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Raposo F,
|
||
Ramos M,
|
||
Lúcia Cruz A</span><br />
|
||
<span class="medgenPMjournal">Musculoskeletal Care</span>
|
||
2021 Dec;19(4):399-435.
|
||
Epub 2021 Mar 5
|
||
doi: 10.1002/msc.1538.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33666347" target="_blank">33666347</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31684921">A consensus-based process identifying physical therapy and exercise treatments for patients with degenerative meniscal tears and knee OA: the TeMPO physical therapy interventions and home exercise program.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Safran-Norton CE,
|
||
Sullivan JK,
|
||
Irrgang JJ,
|
||
Kerman HM,
|
||
Bennell KL,
|
||
Calabrese G,
|
||
Dechaves L,
|
||
Deluca B,
|
||
Gil AB,
|
||
Kale M,
|
||
Luc-Harkey B,
|
||
Selzer F,
|
||
Sople D,
|
||
Tonsoline P,
|
||
Losina E,
|
||
Katz JN</span><br />
|
||
<span class="medgenPMjournal">BMC Musculoskelet Disord</span>
|
||
2019 Nov 4;20(1):514.
|
||
doi: 10.1186/s12891-019-2872-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31684921" target="_blank">31684921</a><a href="/pmc/articles/PMC6830005" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18756654">Glucosamine.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dahmer S,
|
||
Schiller RM</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2008 Aug 15;78(4):471-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18756654" target="_blank">18756654</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14584019">Thermotherapy for treatment of osteoarthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brosseau L,
|
||
Yonge KA,
|
||
Robinson V,
|
||
Marchand S,
|
||
Judd M,
|
||
Wells G,
|
||
Tugwell P</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2003;2003(4):CD004522.
|
||
doi: 10.1002/14651858.CD004522.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14584019" target="_blank">14584019</a><a href="/pmc/articles/PMC6669258" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteoarthritis%2C%20knee%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10441)</a></div><h3 class="subhead">Prognosis</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/38751101">Integrating Radiomics and Neural Networks for Knee Osteoarthritis Incidence Prediction.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Li S,
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Cao P,
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Li J,
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Chen T,
|
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Luo P,
|
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Ruan G,
|
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Zhang Y,
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Wang X,
|
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Han W,
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Zhu Z,
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Dang Q,
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Wang Q,
|
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Zhang M,
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Bai Q,
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Chai Z,
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Yang H,
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Chen H,
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Hunter DJ,
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Ding C</span><br />
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<span class="medgenPMjournal">Arthritis Rheumatol</span>
|
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2024 Sep;76(9):1377-1386.
|
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Epub 2024 Jul 8
|
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doi: 10.1002/art.42915.
|
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<span class="bold">PMID: </span><a href="/pubmed/38751101" target="_blank">38751101</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/37884044">Treatment options for symptomatic knee osteoarthritis in adults.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Clark GP</span><br />
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<span class="medgenPMjournal">JAAPA</span>
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2023 Nov 1;36(11):1-6.
|
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doi: 10.1097/01.JAA.0000979536.73946.98.
|
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<span class="bold">PMID: </span><a href="/pubmed/37884044" target="_blank">37884044</a></div>
|
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<div class="nl"><a target="_blank" href="/pubmed/37684597">The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Øiestad BE,
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Årøen A,
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Røtterud JH,
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2023 Sep 8;24(1):714.
|
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doi: 10.1186/s12891-023-06831-x.
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<span class="bold">PMID: </span><a href="/pubmed/37684597" target="_blank">37684597</a><a href="/pmc/articles/PMC10485991" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/19751691">Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Blagojevic M,
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Jinks C,
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2010 Jan;18(1):24-33.
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doi: 10.1016/j.joca.2009.08.010.
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<span class="bold">PMID: </span><a href="/pubmed/19751691" target="_blank">19751691</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/17761605">The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Lohmander LS,
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Englund PM,
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<span class="medgenPMjournal">Am J Sports Med</span>
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2007 Oct;35(10):1756-69.
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<span class="bold">PMID: </span><a href="/pubmed/17761605" target="_blank">17761605</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteoarthritis%2C%20knee%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6423)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/27998033">Current Physical Activity Monitors in Hip and Knee Osteoarthritis: A Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sliepen M,
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Rosenbaum D</span><br />
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<span class="medgenPMjournal">Arthritis Care Res (Hoboken)</span>
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2017 Oct;69(10):1460-1466.
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Epub 2017 Sep 6
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doi: 10.1002/acr.23170.
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<span class="bold">PMID: </span><a href="/pubmed/27998033" target="_blank">27998033</a><a href="/pmc/articles/PMC5656924" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/26872913">Classifications in Brief: Kellgren-Lawrence Classification of Osteoarthritis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kohn MD,
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Sassoon AA,
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Fernando ND</span><br />
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<span class="medgenPMjournal">Clin Orthop Relat Res</span>
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2016 Aug;474(8):1886-93.
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Epub 2016 Feb 12
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doi: 10.1007/s11999-016-4732-4.
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<span class="bold">PMID: </span><a href="/pubmed/26872913" target="_blank">26872913</a><a href="/pmc/articles/PMC4925407" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/26206679">Predicting Knee Osteoarthritis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gardiner BS,
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Woodhouse FG,
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Besier TF,
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Grodzinsky AJ,
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Lloyd DG,
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Zhang L,
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<span class="medgenPMjournal">Ann Biomed Eng</span>
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2016 Jan;44(1):222-33.
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Epub 2015 Jul 24
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doi: 10.1007/s10439-015-1393-5.
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<span class="bold">PMID: </span><a href="/pubmed/26206679" target="_blank">26206679</a><a href="/pmc/articles/PMC4690844" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/23312418">Targeting care: tailoring nonsurgical management according to clinical presentation.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Eyles J,
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Lucas BR,
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<span class="medgenPMjournal">Rheum Dis Clin North Am</span>
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2013 Feb;39(1):213-33.
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<span class="bold">PMID: </span><a href="/pubmed/23312418" target="_blank">23312418</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/21645627">Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score).</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hunter DJ,
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Guermazi A,
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Lo GH,
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Grainger AJ,
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Conaghan PG,
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Boudreau RM,
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Roemer FW</span><br />
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<span class="medgenPMjournal">Osteoarthritis Cartilage</span>
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2011 Aug;19(8):990-1002.
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Epub 2011 May 23
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doi: 10.1016/j.joca.2011.05.004.
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<span class="bold">PMID: </span><a href="/pubmed/21645627" target="_blank">21645627</a><a href="/pmc/articles/PMC4058435" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteoarthritis%2C%20knee%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (14132)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/35383651">AAOS Clinical Practice Guideline Summary: Management of Osteoarthritis of the Knee (Nonarthroplasty), Third Edition.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Brophy RH,
|
||
Fillingham YA</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Orthop Surg</span>
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||
2022 May 1;30(9):e721-e729.
|
||
doi: 10.5435/JAAOS-D-21-01233.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35383651" target="_blank">35383651</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34356977">The Efficacy of Manual Therapy in Patients with Knee Osteoarthritis: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tsokanos A,
|
||
Livieratou E,
|
||
Billis E,
|
||
Tsekoura M,
|
||
Tatsios P,
|
||
Tsepis E,
|
||
Fousekis K</span><br />
|
||
<span class="medgenPMjournal">Medicina (Kaunas)</span>
|
||
2021 Jul 7;57(7)
|
||
doi: 10.3390/medicina57070696.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34356977" target="_blank">34356977</a><a href="/pmc/articles/PMC8304320" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33846757">Effectiveness of total knee arthroplasty rehabilitation programmes: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alrawashdeh W,
|
||
Eschweiler J,
|
||
Migliorini F,
|
||
El Mansy Y,
|
||
Tingart M,
|
||
Rath B</span><br />
|
||
<span class="medgenPMjournal">J Rehabil Med</span>
|
||
2021 Jun 2;53(6):jrm00200.
|
||
doi: 10.2340/16501977-2827.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33846757" target="_blank">33846757</a><a href="/pmc/articles/PMC8814866" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32542403">Physical Therapist Management of Total Knee Arthroplasty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jette DU,
|
||
Hunter SJ,
|
||
Burkett L,
|
||
Langham B,
|
||
Logerstedt DS,
|
||
Piuzzi NS,
|
||
Poirier NM,
|
||
Radach LJL,
|
||
Ritter JE,
|
||
Scalzitti DA,
|
||
Stevens-Lapsley JE,
|
||
Tompkins J,
|
||
Zeni J Jr;
|
||
American Physical Therapy Association</span><br />
|
||
<span class="medgenPMjournal">Phys Ther</span>
|
||
2020 Aug 31;100(9):1603-1631.
|
||
doi: 10.1093/ptj/pzaa099.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32542403" target="_blank">32542403</a><a href="/pmc/articles/PMC7462050" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26405113">Exercise for osteoarthritis of the knee: a Cochrane systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fransen M,
|
||
McConnell S,
|
||
Harmer AR,
|
||
Van der Esch M,
|
||
Simic M,
|
||
Bennell KL</span><br />
|
||
<span class="medgenPMjournal">Br J Sports Med</span>
|
||
2015 Dec;49(24):1554-7.
|
||
Epub 2015 Sep 24
|
||
doi: 10.1136/bjsports-2015-095424.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26405113" target="_blank">26405113</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteoarthritis%2C%20knee%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1460)</a></div></div>
|
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|
||
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22osteoarthritis%2C%20knee%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Osteoarthritis%2C%20knee%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng226">NICE, 2022</a><div>UK NICE Guideline NG226, Osteoarthritis in over 16s: diagnosis and management, 2022</div></li></ul></div>
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<a href="/pubmed?term=Osteoarthritis,%20knee%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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