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<!--
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UID=871338
|
||
ConceptID=C4025829
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Abnormality of the breast</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>871338</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4025829</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Anatomical Abnormality</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000769">HP:0000769</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">An abnormality of the breast. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Abnormality of the breast</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="matched_ds">Abnormality of the breast</span><ul><li><span class="TLline"><a href="/medgen/1627648" ref="tree=MeSH" title="MedGen record for Abnormal breast morphology">Abnormal breast morphology</a></span><ul><li><span class="TLline"><a href="/medgen/1687090" ref="tree=MeSH" title="MedGen record for Abnormal areolar morphology">Abnormal areolar morphology</a></span><ul><li><span class="TLline"><a href="/medgen/1701489" ref="tree=MeSH" title="MedGen record for Areolar fullness">Areolar fullness</a></span></li><li><span class="TLline"><a href="/medgen/477663" ref="tree=MeSH" title="MedGen record for Hypoplastic areola">Hypoplastic areola</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/824919" ref="tree=MeSH" title="MedGen record for Abnormal nipple morphology">Abnormal nipple morphology</a></span><ul><li><span class="TLline"><a href="/medgen/868021" ref="tree=MeSH" title="MedGen record for Abnormal intermamillary distance">Abnormal intermamillary distance</a></span></li><li><span class="TLline"><a href="/medgen/461436" ref="tree=MeSH" title="MedGen record for Aplasia/Hypoplasia of the nipples">Aplasia/Hypoplasia of the nipples</a></span></li><li><span class="TLline"><a href="/medgen/1623208" ref="tree=MeSH" title="MedGen record for Dry nipple">Dry nipple</a></span></li><li><span class="TLline"><a href="/medgen/1863831" ref="tree=MeSH" title="MedGen record for High-set nipples">High-set nipples</a></span></li><li><span class="TLline"><a href="/medgen/82844" ref="tree=MeSH" title="MedGen record for Inversion of nipple">Inversion of nipple</a></span></li><li><span class="TLline"><a href="/medgen/324640" ref="tree=MeSH" title="MedGen record for Low-set nipples">Low-set nipples</a></span></li><li><span class="TLline"><a href="/medgen/1864406" ref="tree=MeSH" title="MedGen record for Nipple epidermal Paget cells">Nipple epidermal Paget cells</a></span></li><li><span class="TLline"><a href="/medgen/1864296" ref="tree=MeSH" title="MedGen record for Nipple thickening">Nipple thickening</a></span></li><li><span class="TLline"><a href="/medgen/343372" ref="tree=MeSH" title="MedGen record for Prominent nipples">Prominent nipples</a></span></li><li><span class="TLline"><a href="/medgen/120564" ref="tree=MeSH" title="MedGen record for Supernumerary nipple">Supernumerary nipple</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/381317" ref="tree=MeSH" title="MedGen record for Anisomastia">Anisomastia</a></span></li><li><span class="TLline"><a href="/medgen/869484" ref="tree=MeSH" title="MedGen record for Aplasia/Hypoplasia of the breasts">Aplasia/Hypoplasia of the breasts</a></span><ul><li><span class="TLline"><a href="/medgen/539633" ref="tree=MeSH" title="MedGen record for Breast aplasia">Breast aplasia</a></span></li><li><span class="TLline"><a href="/medgen/75594" ref="tree=MeSH" title="MedGen record for Breast hypoplasia">Breast hypoplasia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/692574" ref="tree=MeSH" title="MedGen record for Architectural distortion of breast">Architectural distortion of breast</a></span></li><li><span class="TLline"><a href="/medgen/1864247" ref="tree=MeSH" title="MedGen record for Asymmetric thickening of the nipple-areolar complex">Asymmetric thickening of the nipple-areolar complex</a></span></li><li><span class="TLline"><a href="/medgen/508760" ref="tree=MeSH" title="MedGen record for Breast abscess">Breast abscess</a></span></li><li><span class="TLline"><a href="/medgen/14220" ref="tree=MeSH" title="MedGen record for Breast cyst">Breast cyst</a></span><ul><li><span class="TLline"><a href="/medgen/20866" ref="tree=MeSH" title="MedGen record for Solitary cyst of breast">Solitary cyst of breast</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/43789" ref="tree=MeSH" title="MedGen record for Breast hypertrophy">Breast hypertrophy</a></span></li><li><span class="TLline"><a href="/medgen/6143" ref="tree=MeSH" title="MedGen record for Breast mass">Breast mass</a></span><ul><li><span class="TLline"><a href="/medgen/1863490" ref="tree=MeSH" title="MedGen record for Hypoechoic breast mass">Hypoechoic breast mass</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/105455" ref="tree=MeSH" title="MedGen record for Breast microcalcification">Breast microcalcification</a></span><ul><li><span class="TLline"><a href="/medgen/313432" ref="tree=MeSH" title="MedGen record for Microcalcification Present in Neoplastic and Non-Neoplastic Tissue">Microcalcification Present in Neoplastic and Non-Neoplastic Tissue</a></span></li><li><span class="TLline"><a href="/medgen/353925" ref="tree=MeSH" title="MedGen record for Microcalcification Present in Neoplastic Tissue">Microcalcification Present in Neoplastic Tissue</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/264172" ref="tree=MeSH" title="MedGen record for Breast neoplasm">Breast neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/167809" ref="tree=MeSH" title="MedGen record for Breast adenocarcinoma">Breast adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/231286" ref="tree=MeSH" title="MedGen record for Breast adenoma">Breast adenoma</a></span></li><li><span class="TLline"><a href="/medgen/235590" ref="tree=MeSH" title="MedGen record for Breast apocrine adenoma">Breast apocrine adenoma</a></span></li><li><span class="TLline"><a href="/medgen/91085" ref="tree=MeSH" title="MedGen record for Breast benign neoplasm">Breast benign neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/146260" ref="tree=MeSH" title="MedGen record for Breast carcinoma">Breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/57817" ref="tree=MeSH" title="MedGen record for Breast carcinoma in situ">Breast carcinoma in situ</a></span></li><li><span class="TLline"><a href="/medgen/317529" ref="tree=MeSH" title="MedGen record for Breast Columnar Cell Lesion">Breast Columnar Cell Lesion</a></span></li><li><span class="TLline"><a href="/medgen/267408" ref="tree=MeSH" title="MedGen record for Breast fibroepithelial neoplasm">Breast fibroepithelial neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/107756" ref="tree=MeSH" title="MedGen record for Breast Hyperplasia">Breast Hyperplasia</a></span></li><li><span class="TLline"><a href="/medgen/64634" ref="tree=MeSH" title="MedGen record for Breast lobular carcinoma">Breast lobular carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1863590" ref="tree=MeSH" title="MedGen record for Breast myxoma">Breast myxoma</a></span></li><li><span class="TLline"><a href="/medgen/866340" ref="tree=MeSH" title="MedGen record for Breast Neoplasm, Unilateral">Breast Neoplasm, Unilateral</a></span></li><li><span class="TLline"><a href="/medgen/66983" ref="tree=MeSH" title="MedGen record for Breast Neoplasms, Male">Breast Neoplasms, Male</a></span></li><li><span class="TLline"><a href="/medgen/231969" ref="tree=MeSH" title="MedGen record for Breast neuroendocrine neoplasm">Breast neuroendocrine neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/233308" ref="tree=MeSH" title="MedGen record for Breast Papillary Neoplasm">Breast Papillary Neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/267907" ref="tree=MeSH" title="MedGen record for Breast Soft Tissue Neoplasm">Breast Soft Tissue Neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/765" ref="tree=MeSH" title="MedGen record for Ductal carcinoma in situ">Ductal carcinoma in situ</a></span></li><li><span class="TLline"><a href="/medgen/64231" ref="tree=MeSH" title="MedGen record for Fibroadenoma of the breast">Fibroadenoma of the breast</a></span></li><li><span class="TLline"><a href="/medgen/151793" ref="tree=MeSH" title="MedGen record for Hereditary breast ovarian cancer syndrome">Hereditary breast ovarian cancer syndrome</a></span></li><li><span class="TLline"><a href="/medgen/75841" ref="tree=MeSH" title="MedGen record for Inflammatory breast carcinoma">Inflammatory breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/184927" ref="tree=MeSH" title="MedGen record for Intraductal breast neoplasm">Intraductal breast neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/65944" ref="tree=MeSH" title="MedGen record for Intraductal breast papilloma">Intraductal breast papilloma</a></span></li><li><span class="TLline"><a href="/medgen/79007" ref="tree=MeSH" title="MedGen record for Lobular breast carcinoma in situ">Lobular breast carcinoma in situ</a></span></li><li><span class="TLline"><a href="/medgen/167824" ref="tree=MeSH" title="MedGen record for Lobular neoplasia">Lobular neoplasia</a></span></li><li><span class="TLline"><a href="/medgen/651" ref="tree=MeSH" title="MedGen record for Malignant tumor of breast">Malignant tumor of breast</a></span></li><li><span class="TLline"><a href="/medgen/205111" ref="tree=MeSH" title="MedGen record for Nipple neoplasm">Nipple neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/761659" ref="tree=MeSH" title="MedGen record for Triple-negative breast cancer">Triple-negative breast cancer</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1864056" ref="tree=MeSH" title="MedGen record for Diffuse breast nodularity">Diffuse breast nodularity</a></span></li><li><span class="TLline"><a href="/medgen/1864347" ref="tree=MeSH" title="MedGen record for Fibrocystic breast lesion">Fibrocystic breast lesion</a></span></li><li><span class="TLline"><a href="/medgen/6694" ref="tree=MeSH" title="MedGen record for Gynecomastia">Gynecomastia</a></span><ul><li><span class="TLline"><a href="/medgen/857574" ref="tree=MeSH" title="MedGen record for Pathological Gynecomastia">Pathological Gynecomastia</a></span></li><li><span class="TLline"><a href="/medgen/304256" ref="tree=MeSH" title="MedGen record for Pubertal gynecomastia">Pubertal gynecomastia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/57538" ref="tree=MeSH" title="MedGen record for Mammary duct ectasia">Mammary duct ectasia</a></span><ul><li><span class="TLline"><a href="/medgen/443273" ref="tree=MeSH" title="MedGen record for Focal Mammary Duct Ectasia">Focal Mammary Duct Ectasia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/9901" ref="tree=MeSH" title="MedGen record for Mastitis">Mastitis</a></span><ul><li><span class="TLline"><a href="/medgen/98343" ref="tree=MeSH" title="MedGen record for Granulomatous mastitis">Granulomatous mastitis</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1623013" ref="tree=MeSH" title="MedGen record for Abnormal breast physiology">Abnormal breast physiology</a></span><ul><li><span class="TLline"><a href="/medgen/1863913" ref="tree=MeSH" title="MedGen record for Abnormal nipple discharge">Abnormal nipple discharge</a></span></li><li><span class="TLline"><a href="/medgen/508905" ref="tree=MeSH" title="MedGen record for Agalactia">Agalactia</a></span></li><li><span class="TLline"><a href="/medgen/115998" ref="tree=MeSH" title="MedGen record for Galactorrhea not associated with childbirth">Galactorrhea not associated with childbirth</a></span></li><li><span class="TLline"><a href="/medgen/101829" ref="tree=MeSH" title="MedGen record for Lactocele">Lactocele</a></span></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_10822"><div><strong>Poland anomaly</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>10822</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0032357</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Poland syndrome consists of unilateral absence or hypoplasia of the pectoralis muscle, most frequently involving the sternocostal portion of the pectoralis major muscle, and a variable degree of ipsilateral hand and digit anomalies, including symbrachydactyly. Sometimes called Poland sequence, it was first described by Poland (1841). Poland syndrome is most commonly a sporadic condition (David, 1982; Opitz, 1982), but familial cases have been reported.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/10822">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_66312"><div><strong>Blepharophimosis, ptosis, and epicanthus inversus syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66312</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0220663</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) is defined by a complex eyelid malformation characterized by four major features, all present at birth: blepharophimosis, ptosis, epicanthus inversus, and telecanthus. BPES type I includes the four major features and primary ovarian insufficiency; BPES type II includes only the four major features. Other ophthalmic manifestations that can be associated with BPES include dysplastic eyelids, lacrimal duct anomalies, strabismus, refractive errors, and amblyopia. Other craniofacial features may include a broad nasal bridge and low-set ears.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/66312">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_120520"><div><strong>Ruvalcaba syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120520</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265248</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Ruvalcaba syndrome is an extremely rare malformation syndrome, described in less than 10 patients to date, characterized by microcephaly with characteristic facies (downslanting parpebral fissures, microstomia, beaked nose, narrow maxilla), very short stature, narrow thoracic cage with pectus carinatum, hypoplastic genitalia and skeletal anomalies (i.e. characteristic brachydactyly and osteochondritis of the spine) as well as intellectual and developmental delay.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120520">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_395425"><div><strong>Acro-renal-mandibular syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>395425</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1860166</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A very rare multiple congenital anomalies syndrome with characteristics of limb deficiencies and renal anomalies that include split hand-split foot malformation, renal agenesis, polycystic kidneys, uterine anomalies and severe mandibular hypoplasia.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/395425">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_395425" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Acro-renal-mandibular syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_66312" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Blepharophimosis, ptosis, and epicanthus inversus syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_10822" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Poland anomaly</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120520" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ruvalcaba syndrome</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/10085389">Management of nonpalpable, mammographically detectable breast lesions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Markopoulos C,
|
||
Kakisis J,
|
||
Kouskos S,
|
||
Kontzoglou K,
|
||
Koufopoulos K,
|
||
Gogas J</span><br />
|
||
<span class="medgenPMjournal">World J Surg</span>
|
||
1999 May;23(5):434-8.
|
||
doi: 10.1007/pl00012323.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10085389" target="_blank">10085389</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22abnormality%20of%20the%20breast%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37875774">Hypoprolactinemia. Does it matter? Redefining the hypopituitarism and return from a mumpsimus : "Absence of proof is not the proof of absence".</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karaca Z,
|
||
Unluhizarci K,
|
||
Kelestimur F</span><br />
|
||
<span class="medgenPMjournal">Rev Endocr Metab Disord</span>
|
||
2024 Dec;25(6):943-951.
|
||
Epub 2023 Oct 25
|
||
doi: 10.1007/s11154-023-09847-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37875774" target="_blank">37875774</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36335923">Management of Radiographic Lesions of the Breast.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wiechmann L,
|
||
Friedlander LC</span><br />
|
||
<span class="medgenPMjournal">Surg Clin North Am</span>
|
||
2022 Dec;102(6):1031-1041.
|
||
doi: 10.1016/j.suc.2022.06.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36335923" target="_blank">36335923</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34197218">Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lambertini M,
|
||
Blondeaux E,
|
||
Bruzzone M,
|
||
Perachino M,
|
||
Anderson RA,
|
||
de Azambuja E,
|
||
Poorvu PD,
|
||
Kim HJ,
|
||
Villarreal-Garza C,
|
||
Pistilli B,
|
||
Vaz-Luis I,
|
||
Saura C,
|
||
Ruddy KJ,
|
||
Franzoi MA,
|
||
Sertoli C,
|
||
Ceppi M,
|
||
Azim HA Jr,
|
||
Amant F,
|
||
Demeestere I,
|
||
Del Mastro L,
|
||
Partridge AH,
|
||
Pagani O,
|
||
Peccatori FA</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2021 Oct 10;39(29):3293-3305.
|
||
Epub 2021 Jul 1
|
||
doi: 10.1200/JCO.21.00535.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34197218" target="_blank">34197218</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20965141">Redefining gigantomastia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dafydd H,
|
||
Roehl KR,
|
||
Phillips LG,
|
||
Dancey A,
|
||
Peart F,
|
||
Shokrollahi K</span><br />
|
||
<span class="medgenPMjournal">J Plast Reconstr Aesthet Surg</span>
|
||
2011 Feb;64(2):160-3.
|
||
Epub 2010 Jun 8
|
||
doi: 10.1016/j.bjps.2010.04.043.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20965141" target="_blank">20965141</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18486842">Benign breast disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miltenburg DM,
|
||
Speights VO Jr</span><br />
|
||
<span class="medgenPMjournal">Obstet Gynecol Clin North Am</span>
|
||
2008 Jun;35(2):285-300, ix.
|
||
doi: 10.1016/j.ogc.2008.03.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18486842" target="_blank">18486842</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormality%20of%20the%20breast%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (931)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37875774">Hypoprolactinemia. Does it matter? Redefining the hypopituitarism and return from a mumpsimus : "Absence of proof is not the proof of absence".</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karaca Z,
|
||
Unluhizarci K,
|
||
Kelestimur F</span><br />
|
||
<span class="medgenPMjournal">Rev Endocr Metab Disord</span>
|
||
2024 Dec;25(6):943-951.
|
||
Epub 2023 Oct 25
|
||
doi: 10.1007/s11154-023-09847-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37875774" target="_blank">37875774</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36335923">Management of Radiographic Lesions of the Breast.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wiechmann L,
|
||
Friedlander LC</span><br />
|
||
<span class="medgenPMjournal">Surg Clin North Am</span>
|
||
2022 Dec;102(6):1031-1041.
|
||
doi: 10.1016/j.suc.2022.06.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36335923" target="_blank">36335923</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33691563">Idiopathic Granulomatous Mastitis: Etiology, Clinical Manifestation, Diagnosis and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yin Y,
|
||
Liu X,
|
||
Meng Q,
|
||
Han X,
|
||
Zhang H,
|
||
Lv Y</span><br />
|
||
<span class="medgenPMjournal">J Invest Surg</span>
|
||
2022 Mar;35(3):709-720.
|
||
Epub 2021 Mar 10
|
||
doi: 10.1080/08941939.2021.1894516.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33691563" target="_blank">33691563</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34197218">Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Lambertini M,
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Blondeaux E,
|
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Bruzzone M,
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Perachino M,
|
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Anderson RA,
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de Azambuja E,
|
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Poorvu PD,
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Kim HJ,
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Villarreal-Garza C,
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Pistilli B,
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Vaz-Luis I,
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Saura C,
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Ruddy KJ,
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Franzoi MA,
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Sertoli C,
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Ceppi M,
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Azim HA Jr,
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Amant F,
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Demeestere I,
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Del Mastro L,
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Partridge AH,
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Pagani O,
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Peccatori FA</span><br />
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2021 Oct 10;39(29):3293-3305.
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Epub 2021 Jul 1
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<span class="bold">PMID: </span><a href="/pubmed/34197218" target="_blank">34197218</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30837078">Lymphovascular malformation of the breast: differential diagnosis and a case report.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Marín C,
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J Galindo P,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormality%20of%20the%20breast%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1092)</a></div><h3 class="subhead">Therapy</h3>
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<div class="nl"><a target="_blank" href="/pubmed/34197218">Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lambertini M,
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Blondeaux E,
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Bruzzone M,
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Perachino M,
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Anderson RA,
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de Azambuja E,
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Poorvu PD,
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Kim HJ,
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Villarreal-Garza C,
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Pistilli B,
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Vaz-Luis I,
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Saura C,
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Ruddy KJ,
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Franzoi MA,
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<span class="bold">PMID: </span><a href="/pubmed/34197218" target="_blank">34197218</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/33314370" target="_blank">33314370</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32560062">Nipple-Areola Complex Reconstruction.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sisti A</span><br />
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormality%20of%20the%20breast%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (376)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/35781795">Estetrol/Drospirenone: A Review in Oral Contraception.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lee A,
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Syed YY</span><br />
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<span class="medgenPMjournal">Drugs</span>
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2022 Jul;82(10):1117-1125.
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Epub 2022 Jul 4
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doi: 10.1007/s40265-022-01738-8.
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<span class="bold">PMID: </span><a href="/pubmed/35781795" target="_blank">35781795</a><a href="/pmc/articles/PMC9363382" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/34505197" target="_blank">34505197</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Waldman RA,
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Finch J,
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Md Nasir ND,
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Thike AA,
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Lee JYH,
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<span class="bold">PMID: </span><a href="/pubmed/29248888" target="_blank">29248888</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/20429767">Breast plasmacytoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Surov A,
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Holzhausen HJ,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormality%20of%20the%20breast%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (563)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/33691563">Idiopathic Granulomatous Mastitis: Etiology, Clinical Manifestation, Diagnosis and Treatment.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Yin Y,
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Liu X,
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<span class="bold">PMID: </span><a href="/pubmed/33691563" target="_blank">33691563</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34197218">Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lambertini M,
|
||
Blondeaux E,
|
||
Bruzzone M,
|
||
Perachino M,
|
||
Anderson RA,
|
||
de Azambuja E,
|
||
Poorvu PD,
|
||
Kim HJ,
|
||
Villarreal-Garza C,
|
||
Pistilli B,
|
||
Vaz-Luis I,
|
||
Saura C,
|
||
Ruddy KJ,
|
||
Franzoi MA,
|
||
Sertoli C,
|
||
Ceppi M,
|
||
Azim HA Jr,
|
||
Amant F,
|
||
Demeestere I,
|
||
Del Mastro L,
|
||
Partridge AH,
|
||
Pagani O,
|
||
Peccatori FA</span><br />
|
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<span class="medgenPMjournal">J Clin Oncol</span>
|
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2021 Oct 10;39(29):3293-3305.
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Epub 2021 Jul 1
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doi: 10.1200/JCO.21.00535.
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<span class="bold">PMID: </span><a href="/pubmed/34197218" target="_blank">34197218</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29487204">Metabolic reprogramming in type 2 diabetes and the development of breast cancer.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Martin SD,
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McGee SL</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/29487204" target="_blank">29487204</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29248888">Genetics and genomics of breast fibroadenomas.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Loke BN,
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Md Nasir ND,
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Thike AA,
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Lee JYH,
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Lee CS,
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Teh BT,
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Tan PH</span><br />
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<span class="medgenPMjournal">J Clin Pathol</span>
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2018 May;71(5):381-387.
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Epub 2017 Dec 16
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doi: 10.1136/jclinpath-2017-204838.
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<span class="bold">PMID: </span><a href="/pubmed/29248888" target="_blank">29248888</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25185646">Angiogenesis and tumor microenvironment: bevacizumab in the breast cancer model.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Trédan O,
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Lacroix-Triki M,
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Guiu S,
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Mouret-Reynier MA,
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Barrière J,
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Bidard FC,
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Braccini AL,
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Mir O,
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<span class="bold">PMID: </span><a href="/pubmed/25185646" target="_blank">25185646</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormality%20of%20the%20breast%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (597)</a></div></div>
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</div>
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|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/39467394">The incidence of male breast cancer in Klinefelter Syndrome and its proposed mechanisms.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Cook B,
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Nayar S,
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Filson S,
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Yap T</span><br />
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<span class="medgenPMjournal">Breast</span>
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2024 Dec;78:103827.
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Epub 2024 Oct 24
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||
doi: 10.1016/j.breast.2024.103827.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39467394" target="_blank">39467394</a><a href="/pmc/articles/PMC11549982" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34197218">Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lambertini M,
|
||
Blondeaux E,
|
||
Bruzzone M,
|
||
Perachino M,
|
||
Anderson RA,
|
||
de Azambuja E,
|
||
Poorvu PD,
|
||
Kim HJ,
|
||
Villarreal-Garza C,
|
||
Pistilli B,
|
||
Vaz-Luis I,
|
||
Saura C,
|
||
Ruddy KJ,
|
||
Franzoi MA,
|
||
Sertoli C,
|
||
Ceppi M,
|
||
Azim HA Jr,
|
||
Amant F,
|
||
Demeestere I,
|
||
Del Mastro L,
|
||
Partridge AH,
|
||
Pagani O,
|
||
Peccatori FA</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2021 Oct 10;39(29):3293-3305.
|
||
Epub 2021 Jul 1
|
||
doi: 10.1200/JCO.21.00535.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34197218" target="_blank">34197218</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34106427">Loco-regional therapy and the risk of breast cancer-related lymphedema: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin Y,
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||
Xu Y,
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||
Wang C,
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||
Song Y,
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||
Huang X,
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||
Zhang X,
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||
Cao X,
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||
Sun Q</span><br />
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||
<span class="medgenPMjournal">Breast Cancer</span>
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||
2021 Nov;28(6):1261-1272.
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||
Epub 2021 Jun 9
|
||
doi: 10.1007/s12282-021-01263-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34106427" target="_blank">34106427</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27476082">Treatment of the benign inverted nipple: A systematic review and recommendations for future therapy.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Hernandez Yenty QM,
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Jurgens WJ,
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van Zuijlen PP,
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de Vet HC,
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Verhaegen PD</span><br />
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<span class="medgenPMjournal">Breast</span>
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2016 Oct;29:82-9.
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Epub 2016 Jul 29
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<span class="bold">PMID: </span><a href="/pubmed/27476082" target="_blank">27476082</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/22488516">Applicability and safety of autologous fat for reconstruction of the breast.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Claro F Jr,
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Figueiredo JC,
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Zampar AG,
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<span class="medgenPMjournal">Br J Surg</span>
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<span class="bold">PMID: </span><a href="/pubmed/22488516" target="_blank">22488516</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormality%20of%20the%20breast%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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|
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|
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|
||
|
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|
||
</div>
|
||
<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
|
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|
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|
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|
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