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<meta name="keywords" content="C4025656, abnormal cholesterol homeostasis, abnormal circulating cholesterol concentration, abnormality of cholesterol metabolism, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Any deviation from the normal concentration of cholesterol in the blood circulation." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=871179
|
||
ConceptID=C4025656
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Abnormal circulating cholesterol concentration</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>871179</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4025656</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Abnormality of cholesterol metabolism</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0003107">HP:0003107</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Any deviation from the normal concentration of cholesterol in the blood circulation. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Abnormal circulating cholesterol concentration</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1701080" ref="tree=MeSH" title="MedGen record for Abnormal circulating metabolite concentration">Abnormal circulating metabolite concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1864085" ref="tree=MeSH" title="MedGen record for Abnormal circulating organic compound concentration">Abnormal circulating organic compound concentration</a></span><ul><li><span class="TLline"><a href="/medgen/892402" ref="tree=MeSH" title="MedGen record for Abnormal circulating lipid concentration">Abnormal circulating lipid concentration</a></span><ul><li><span class="matched_ds">Abnormal circulating cholesterol concentration</span><ul><li><span class="TLline"><a href="/medgen/1841673" ref="tree=MeSH" title="MedGen record for Abnormal circulating 7-dehydrocholesterol concentration">Abnormal circulating 7-dehydrocholesterol concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1841805" ref="tree=MeSH" title="MedGen record for Decreased circulating 7-dehydrocholesterol concentration">Decreased circulating 7-dehydrocholesterol concentration</a></span></li><li><span class="TLline"><a href="/medgen/376537" ref="tree=MeSH" title="MedGen record for Elevated circulating 7-dehydrocholesterol concentration">Elevated circulating 7-dehydrocholesterol concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/869193" ref="tree=MeSH" title="MedGen record for Abnormality of lipoprotein cholesterol concentration">Abnormality of lipoprotein cholesterol concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1642949" ref="tree=MeSH" title="MedGen record for Abnormal chylomicron concentration">Abnormal chylomicron concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1619771" ref="tree=MeSH" title="MedGen record for Decreased circulating chylomicron concentration">Decreased circulating chylomicron concentration</a></span></li><li><span class="TLline"><a href="/medgen/853340" ref="tree=MeSH" title="MedGen record for Increased circulating chylomicron concentration">Increased circulating chylomicron concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1640068" ref="tree=MeSH" title="MedGen record for Abnormal HDL cholesterol concentration">Abnormal HDL cholesterol concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1695991" ref="tree=MeSH" title="MedGen record for Abnormal HDL subfraction concentration">Abnormal HDL subfraction concentration</a></span></li><li><span class="TLline"><a href="/medgen/57731" ref="tree=MeSH" title="MedGen record for Decreased HDL cholesterol concentration">Decreased HDL cholesterol concentration</a></span></li><li><span class="TLline"><a href="/medgen/1636134" ref="tree=MeSH" title="MedGen record for Increased HDL cholesterol concentration">Increased HDL cholesterol concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1639134" ref="tree=MeSH" title="MedGen record for Abnormal LDL cholesterol concentration">Abnormal LDL cholesterol concentration</a></span><ul><li><span class="TLline"><a href="/medgen/776554" ref="tree=MeSH" title="MedGen record for Decreased LDL cholesterol concentration">Decreased LDL cholesterol concentration</a></span></li><li><span class="TLline"><a href="/medgen/154289" ref="tree=MeSH" title="MedGen record for Increased LDL cholesterol concentration">Increased LDL cholesterol concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1633574" ref="tree=MeSH" title="MedGen record for Abnormal VLDL cholesterol concentration">Abnormal VLDL cholesterol concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1625610" ref="tree=MeSH" title="MedGen record for Decreased VLDL cholesterol concentration">Decreased VLDL cholesterol concentration</a></span></li><li><span class="TLline"><a href="/medgen/867364" ref="tree=MeSH" title="MedGen record for Increased VLDL cholesterol concentration">Increased VLDL cholesterol concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/9363" ref="tree=MeSH" title="MedGen record for Hyperlipoproteinemia">Hyperlipoproteinemia</a></span><ul><li><span class="TLline"><a href="/medgen/1863424" ref="tree=MeSH" title="MedGen record for Abnormal circulating lipoprotein(a) concentration">Abnormal circulating lipoprotein(a) concentration</a></span></li><li><span class="TLline"><a href="/medgen/5688" ref="tree=MeSH" title="MedGen record for Familial hypercholesterolemia">Familial hypercholesterolemia</a></span></li><li><span class="TLline"><a href="/medgen/9364" ref="tree=MeSH" title="MedGen record for Familial type 3 hyperlipoproteinemia">Familial type 3 hyperlipoproteinemia</a></span></li><li><span class="TLline"><a href="/medgen/5693" ref="tree=MeSH" title="MedGen record for Familial type 5 hyperlipoproteinemia">Familial type 5 hyperlipoproteinemia</a></span></li><li><span class="TLline"><a href="/medgen/87465" ref="tree=MeSH" title="MedGen record for Hyperalphalipoproteinemia">Hyperalphalipoproteinemia</a></span></li><li><span class="TLline"><a href="/medgen/309962" ref="tree=MeSH" title="MedGen record for Hypercholesterolemia, autosomal dominant, type B">Hypercholesterolemia, autosomal dominant, type B</a></span></li><li><span class="TLline"><a href="/medgen/152875" ref="tree=MeSH" title="MedGen record for Hypercholesterolemia, familial, 1">Hypercholesterolemia, familial, 1</a></span></li><li><span class="TLline"><a href="/medgen/400313" ref="tree=MeSH" title="MedGen record for Hypercholesterolemia, familial, 4">Hypercholesterolemia, familial, 4</a></span></li><li><span class="TLline"><a href="/medgen/9365" ref="tree=MeSH" title="MedGen record for Hyperlipoproteinemia type IV">Hyperlipoproteinemia type IV</a></span></li><li><span class="TLline"><a href="/medgen/7352" ref="tree=MeSH" title="MedGen record for Hyperlipoproteinemia, type I">Hyperlipoproteinemia, type I</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/6982" ref="tree=MeSH" title="MedGen record for Hypolipoproteinemia">Hypolipoproteinemia</a></span><ul><li><span class="TLline"><a href="/medgen/96877" ref="tree=MeSH" title="MedGen record for Hypoalphalipoproteinemia">Hypoalphalipoproteinemia</a></span></li><li><span class="TLline"><a href="/medgen/6978" ref="tree=MeSH" title="MedGen record for Hypobetalipoproteinemia">Hypobetalipoproteinemia</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1691039" ref="tree=MeSH" title="MedGen record for Decreased low-density lipoprotein particle size">Decreased low-density lipoprotein particle size</a></span></li><li><span class="TLline"><a href="/medgen/327010" ref="tree=MeSH" title="MedGen record for Elevated 8(9)-cholestenol">Elevated 8(9)-cholestenol</a></span></li><li><span class="TLline"><a href="/medgen/333461" ref="tree=MeSH" title="MedGen record for Elevated 8-dehydrocholesterol">Elevated 8-dehydrocholesterol</a></span></li><li><span class="TLline"><a href="/medgen/713473" ref="tree=MeSH" title="MedGen record for Elevated cholesterol ester level">Elevated cholesterol ester level</a></span></li><li><span class="TLline"><a href="/medgen/1863593" ref="tree=MeSH" title="MedGen record for Elevated circulating 27-hydroxycholesterol concentration">Elevated circulating 27-hydroxycholesterol concentration</a></span></li><li><span class="TLline"><a href="/medgen/1863478" ref="tree=MeSH" title="MedGen record for Elevated circulating cholestanol concentration">Elevated circulating cholestanol concentration</a></span></li><li><span class="TLline"><a href="/medgen/1864174" ref="tree=MeSH" title="MedGen record for Elevated circulating cholesterol sulfate concentration">Elevated circulating cholesterol sulfate concentration</a></span></li><li><span class="TLline"><a href="/medgen/1841991" ref="tree=MeSH" title="MedGen record for Elevated circulating desmosterol concentration">Elevated circulating desmosterol concentration</a></span></li><li><span class="TLline"><a href="/medgen/1841581" ref="tree=MeSH" title="MedGen record for Elevated circulating lathosterol concentration">Elevated circulating lathosterol concentration</a></span></li><li><span class="TLline"><a href="/medgen/5687" ref="tree=MeSH" title="MedGen record for Hypercholesterolemia">Hypercholesterolemia</a></span></li><li><span class="TLline"><a href="/medgen/57479" ref="tree=MeSH" title="MedGen record for Hypocholesterolemia">Hypocholesterolemia</a></span></li><li><span class="TLline"><a href="/medgen/1781215" ref="tree=MeSH" title="MedGen record for Increased non-HDL cholesterol concentration">Increased non-HDL cholesterol concentration</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_116041"><div><strong>Cholestanol storage disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>116041</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0238052</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cerebrotendinous xanthomatosis (CTX) is a lipid storage disease characterized by infantile-onset diarrhea, childhood-onset cataract, adolescent- to young adult-onset tendon xanthomas, and adult-onset progressive neurologic dysfunction (dementia, psychiatric disturbances, pyramidal and/or cerebellar signs, dystonia, atypical parkinsonism, peripheral neuropathy, and seizures). Chronic diarrhea from infancy and/or neonatal cholestasis may be the earliest clinical manifestation. In approximately 75% of affected individuals, cataracts are the first finding, often appearing in the first decade of life. Xanthomas appear in the second or third decade; they occur on the Achilles tendon, the extensor tendons of the elbow and hand, the patellar tendon, and the neck tendons. Xanthomas have been reported in the lung, bones, and central nervous system. Some individuals show cognitive impairment from early infancy, whereas the majority have normal or only slightly impaired intellectual function until puberty; dementia with slow deterioration in intellectual abilities occurs in the third decade in more than 50% of individuals. Neuropsychiatric symptoms such as behavioral changes, hallucinations, agitation, aggression, depression, and suicide attempts may be prominent. Pyramidal signs (i.e., spasticity) and/or cerebellar signs almost invariably become evident between ages 20 and 30 years. The biochemical abnormalities that distinguish CTX from other conditions with xanthomas include high plasma and tissue cholestanol concentration, normal-to-low plasma cholesterol concentration, decreased chenodeoxycholic acid (CDCA), increased concentration of bile alcohols and their glyconjugates, and increased concentrations of cholestanol and apolipoprotein B in cerebrospinal fluid.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/116041">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_376521"><div><strong>Hereditary spastic paraplegia 5A</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>376521</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1849115</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Spastic paraplegia-5A (SPG5A) is an autosomal recessive neurologic disorder with a wide phenotypic spectrum. Some patients have pure spastic paraplegia affecting only gait, whereas others may have a complicated phenotype with additional manifestations, including optic atrophy or cerebellar ataxia (summary by Arnoldi et al., 2012). The hereditary spastic paraplegias (SPG) are a group of clinically and genetically diverse disorders characterized by progressive, usually severe, lower extremity spasticity; see reviews of Fink et al. (1996) and Fink (1997). Inheritance is most often autosomal dominant (see 182600), but X-linked (see 303350) and autosomal recessive forms also occur. Genetic Heterogeneity of Autosomal Recessive Spastic Paraplegia Autosomal recessive forms of SPG include SPG7 (607259), caused by mutation in the paraplegin gene (602783) on chromosome 16q24; SPG9B (616586), caused by mutation in the ALDH18A1 gene (138250) on 10q24; SPG11 (604360), caused by mutation in the spatacsin gene (610844) on 15q21; SPG15 (270700), caused by mutation in the ZFYVE26 gene (612012) on 14q24; SPG18 (611225), caused by mutation in the ERLIN2 gene (611605) on 8p11; SPG20 (275900), caused by mutation in the spartin gene (607111) on 13q12; SPG21 (248900), caused by mutation in the maspardin gene (608181) on 15q21; SPG26 (609195), caused by mutation in the B4GALNT1 gene (601873) on 12q13; SPG28 (609340), caused by mutation in the DDHD1 gene (614603) on 14q22; SPG30 (610357), caused by mutation in the KIF1A gene (601255) on 2q37; SPG35 (612319), caused by mutation in the FA2H gene (611026) on 16q23; SPG39 (612020), caused by mutation in the PNPLA6 gene (603197) on 19p13; SPG43 (615043), caused by mutation in the C19ORF12 gene (614297) on 19q12; SPG44 (613206), caused by mutation in the GJC2 gene (608803) on 1q42; SPG45 (613162), caused by mutation in the NT5C2 gene (600417) on 10q24; SPG46 (614409), caused by mutation in the GBA2 gene (609471) on 9p13; SPG48 (613647), caused by mutation in the KIAA0415 gene (613653) on 7p22; SPG50 (612936), caused by mutation in the AP4M1 gene (602296) on 7q22; SPG51 (613744), caused by mutation in the AP4E1 gene (607244) on 15q21; SPG52 (614067), caused by mutation in the AP4S1 gene (607243) on 14q12; SPG53 (614898), caused by mutation in the VPS37A gene (609927) on 8p22; SPG54 (615033), caused by mutation in the DDHD2 gene (615003) on 8p11; SPG55 (615035), caused by mutation in the MTRFR gene on 12q24; SPG56 (615030), caused by mutation in the CYP2U1 gene (610670) on 4q25; SPG57 (615658), caused by mutation in the TFG gene (602498) on 3q12; SPG61 (615685), caused by mutation in the ARL6IP1 gene (607669) on 1p12; SPG62 (615681), caused by mutation in the ERLIN1 gene on 10q24; SPG63 (615686), caused by mutation in the AMPD2 gene (102771) on 1p13; SPG64 (615683), caused by mutation in the ENTPD1 gene (601752) on 10q24; SPG72 (615625), caused by mutation in the REEP2 gene (609347) on 5q31; SPG74 (616451), caused by mutation in the IBA57 gene (615316) on 1q42; SPG75 (616680), caused by mutation in the MAG gene (159460) on 19q13; SPG76 (616907), caused by mutation in the CAPN1 gene (114220) on 11q13; SPG77 (617046), caused by mutation in the FARS2 gene (611592) on 6p25; SPG78 (617225), caused by mutation in the ATP13A2 gene (610513) on 1p36; SPG79 (615491), caused by mutation in the UCHL1 gene (191342) on 4p13; SPG81 (618768), caused by mutation in the SELENOI gene (607915) on 2p23; SPG82 (618770), caused by mutation in the PCYT2 gene (602679) on 17q25; SPG83 (619027), caused by mutation in the HPDL gene (618994) on 1p34; SPG84 (619621), caused by mutation in the PI4KA gene (600286) on 22q11; SPG85 (619686), caused by mutation in the RNF170 gene (614649) on 8p11; SPG86 (619735), caused by mutation in the ABHD16A gene (142620) on 6p21; SPG87 (619966), caused by mutation in the TMEM63C gene (619953) on 14q24; SPG89 (620379), caused by mutation in the AMFR gene (603243) on 16q13; SPG90B (620417), caused by mutation in the SPTSSA gene (613540) on 14q13; SPG92 (620911), caused by mutation in the FICD gene (620875) on chromosome 12q23; and SPG93 (620938), caused by mutation in the NFU1 gene (608100) on chromosome 2p13. Additional autosomal recessive forms of SPG have been mapped to chromosomes 3q (SPG14; 605229), 13q14 (SPG24; 607584), 6q (SPG25; 608220), and 10q22 (SPG27; 609041). A disorder that was formerly designated SPG49 has been reclassified as hereditary sensory and autonomic neuropathy-9 with developmental delay (HSAN9; 615031).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/376521">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_400801"><div><strong>Desmosterolosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>400801</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1865596</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Desmosterolosis is a rare autosomal recessive disorder characterized by multiple congenital anomalies and elevated levels of the cholesterol precursor desmosterol in plasma, tissue, and cultured cells (summary by Waterham et al., 2001).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/400801">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_116041" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cholestanol storage disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_400801" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Desmosterolosis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_376521" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary spastic paraplegia 5A</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/29154418">Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang K,
|
||
Deng HB,
|
||
Man AWC,
|
||
Song E,
|
||
Zhang J,
|
||
Luo C,
|
||
Cheung BMY,
|
||
Yuen KY,
|
||
Jensen PS,
|
||
Irmukhamedov A,
|
||
Elie AGIM,
|
||
Vanhoutte PM,
|
||
Xu A,
|
||
De Mey JGR,
|
||
Wang Y</span><br />
|
||
<span class="medgenPMjournal">ESC Heart Fail</span>
|
||
2017 Nov;4(4):563-575.
|
||
Epub 2017 Jun 27
|
||
doi: 10.1002/ehf2.12183.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29154418" target="_blank">29154418</a><a href="/pmc/articles/PMC5695172" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22683130">Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tricco AC,
|
||
Ivers NM,
|
||
Grimshaw JM,
|
||
Moher D,
|
||
Turner L,
|
||
Galipeau J,
|
||
Halperin I,
|
||
Vachon B,
|
||
Ramsay T,
|
||
Manns B,
|
||
Tonelli M,
|
||
Shojania K</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2012 Jun 16;379(9833):2252-61.
|
||
Epub 2012 Jun 9
|
||
doi: 10.1016/S0140-6736(12)60480-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22683130" target="_blank">22683130</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8964574">Clinical utility of sex hormone-binding globulin measurement.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pugeat M,
|
||
Crave JC,
|
||
Tourniaire J,
|
||
Forest MG</span><br />
|
||
<span class="medgenPMjournal">Horm Res</span>
|
||
1996;45(3-5):148-55.
|
||
doi: 10.1159/000184778.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8964574" target="_blank">8964574</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(abnormal%20circulating%20cholesterol%20concentration)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (9)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37678743">Nuclear Magnetic Resonance-Based Metabolomics and Risk of CKD.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Geng TT,
|
||
Chen JX,
|
||
Lu Q,
|
||
Wang PL,
|
||
Xia PF,
|
||
Zhu K,
|
||
Li Y,
|
||
Guo KQ,
|
||
Yang K,
|
||
Liao YF,
|
||
Zhou YF,
|
||
Liu G,
|
||
Pan A</span><br />
|
||
<span class="medgenPMjournal">Am J Kidney Dis</span>
|
||
2024 Jan;83(1):9-17.
|
||
Epub 2023 Sep 9
|
||
doi: 10.1053/j.ajkd.2023.05.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37678743" target="_blank">37678743</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37353908">PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Millán-de-Meer M,
|
||
Luque-Ramírez M,
|
||
Nattero-Chávez L,
|
||
Escobar-Morreale HF</span><br />
|
||
<span class="medgenPMjournal">Hum Reprod Update</span>
|
||
2023 Nov 2;29(6):741-772.
|
||
doi: 10.1093/humupd/dmad015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37353908" target="_blank">37353908</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34043628">Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Varma VR,
|
||
Wang Y,
|
||
An Y,
|
||
Varma S,
|
||
Bilgel M,
|
||
Doshi J,
|
||
Legido-Quigley C,
|
||
Delgado JC,
|
||
Oommen AM,
|
||
Roberts JA,
|
||
Wong DF,
|
||
Davatzikos C,
|
||
Resnick SM,
|
||
Troncoso JC,
|
||
Pletnikova O,
|
||
O'Brien R,
|
||
Hak E,
|
||
Baak BN,
|
||
Pfeiffer R,
|
||
Baloni P,
|
||
Mohmoudiandehkordi S,
|
||
Nho K,
|
||
Kaddurah-Daouk R,
|
||
Bennett DA,
|
||
Gadalla SM,
|
||
Thambisetty M</span><br />
|
||
<span class="medgenPMjournal">PLoS Med</span>
|
||
2021 May;18(5):e1003615.
|
||
Epub 2021 May 27
|
||
doi: 10.1371/journal.pmed.1003615.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34043628" target="_blank">34043628</a><a href="/pmc/articles/PMC8158920" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29706426">Cholecystectomy and risk of metabolic syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Di Ciaula A,
|
||
Garruti G,
|
||
Wang DQ,
|
||
Portincasa P</span><br />
|
||
<span class="medgenPMjournal">Eur J Intern Med</span>
|
||
2018 Jul;53:3-11.
|
||
Epub 2018 Apr 26
|
||
doi: 10.1016/j.ejim.2018.04.019.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29706426" target="_blank">29706426</a><a href="/pmc/articles/PMC8118133" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22683130">Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tricco AC,
|
||
Ivers NM,
|
||
Grimshaw JM,
|
||
Moher D,
|
||
Turner L,
|
||
Galipeau J,
|
||
Halperin I,
|
||
Vachon B,
|
||
Ramsay T,
|
||
Manns B,
|
||
Tonelli M,
|
||
Shojania K</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2012 Jun 16;379(9833):2252-61.
|
||
Epub 2012 Jun 9
|
||
doi: 10.1016/S0140-6736(12)60480-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22683130" target="_blank">22683130</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20cholesterol%20concentration%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (129)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37353908">PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Millán-de-Meer M,
|
||
Luque-Ramírez M,
|
||
Nattero-Chávez L,
|
||
Escobar-Morreale HF</span><br />
|
||
<span class="medgenPMjournal">Hum Reprod Update</span>
|
||
2023 Nov 2;29(6):741-772.
|
||
doi: 10.1093/humupd/dmad015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37353908" target="_blank">37353908</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34662439">Lipoprotein Z, a hepatotoxic lipoprotein, predicts outcome in alcohol-associated hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hu K,
|
||
Perez-Matos MC,
|
||
Argemi J,
|
||
Vilar-Gomez E,
|
||
Shalaurova I,
|
||
Bullitt E,
|
||
Landeen L,
|
||
Sugahara G,
|
||
Deng H,
|
||
Mathur K,
|
||
Tran S,
|
||
Cai H,
|
||
He H,
|
||
Yalcin Y,
|
||
Vieira Barbosa J,
|
||
Ventura-Cots M,
|
||
Marx K,
|
||
Gad AP,
|
||
Niezen S,
|
||
Izunza Barba S,
|
||
Ang LH,
|
||
Popov YV,
|
||
Fricker Z,
|
||
Lai M,
|
||
Curry M,
|
||
Afdhal N,
|
||
Szabo G,
|
||
Mukamal KJ,
|
||
Sanyal AJ,
|
||
Otvos JD,
|
||
Malik R,
|
||
Saito T,
|
||
Connelly MA,
|
||
Chalasani NP,
|
||
Bataller R,
|
||
Jiang ZG</span><br />
|
||
<span class="medgenPMjournal">Hepatology</span>
|
||
2022 Apr;75(4):968-982.
|
||
Epub 2021 Dec 7
|
||
doi: 10.1002/hep.32203.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34662439" target="_blank">34662439</a><a href="/pmc/articles/PMC9299888" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29154418">Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang K,
|
||
Deng HB,
|
||
Man AWC,
|
||
Song E,
|
||
Zhang J,
|
||
Luo C,
|
||
Cheung BMY,
|
||
Yuen KY,
|
||
Jensen PS,
|
||
Irmukhamedov A,
|
||
Elie AGIM,
|
||
Vanhoutte PM,
|
||
Xu A,
|
||
De Mey JGR,
|
||
Wang Y</span><br />
|
||
<span class="medgenPMjournal">ESC Heart Fail</span>
|
||
2017 Nov;4(4):563-575.
|
||
Epub 2017 Jun 27
|
||
doi: 10.1002/ehf2.12183.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29154418" target="_blank">29154418</a><a href="/pmc/articles/PMC5695172" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12419478">Measurement issues related to lipoprotein heterogeneity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Otvos JD,
|
||
Jeyarajah EJ,
|
||
Cromwell WC</span><br />
|
||
<span class="medgenPMjournal">Am J Cardiol</span>
|
||
2002 Oct 17;90(8A):22i-29i.
|
||
doi: 10.1016/s0002-9149(02)02632-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12419478" target="_blank">12419478</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4120849">Grades of hypothyroidism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Evered DC,
|
||
Ormston BJ,
|
||
Smith PA,
|
||
Hall R,
|
||
Bird T</span><br />
|
||
<span class="medgenPMjournal">Br Med J</span>
|
||
1973 Mar 17;1(5854):657-62.
|
||
doi: 10.1136/bmj.1.5854.657.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4120849" target="_blank">4120849</a><a href="/pmc/articles/PMC1588654" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20cholesterol%20concentration%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (47)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37353908">PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Millán-de-Meer M,
|
||
Luque-Ramírez M,
|
||
Nattero-Chávez L,
|
||
Escobar-Morreale HF</span><br />
|
||
<span class="medgenPMjournal">Hum Reprod Update</span>
|
||
2023 Nov 2;29(6):741-772.
|
||
doi: 10.1093/humupd/dmad015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37353908" target="_blank">37353908</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22683130">Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tricco AC,
|
||
Ivers NM,
|
||
Grimshaw JM,
|
||
Moher D,
|
||
Turner L,
|
||
Galipeau J,
|
||
Halperin I,
|
||
Vachon B,
|
||
Ramsay T,
|
||
Manns B,
|
||
Tonelli M,
|
||
Shojania K</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2012 Jun 16;379(9833):2252-61.
|
||
Epub 2012 Jun 9
|
||
doi: 10.1016/S0140-6736(12)60480-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22683130" target="_blank">22683130</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12700179">Androgens and coronary artery disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wu FC,
|
||
von Eckardstein A</span><br />
|
||
<span class="medgenPMjournal">Endocr Rev</span>
|
||
2003 Apr;24(2):183-217.
|
||
doi: 10.1210/er.2001-0025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12700179" target="_blank">12700179</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8831910">Lipids, risk factors and ischaemic heart disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Castelli WP</span><br />
|
||
<span class="medgenPMjournal">Atherosclerosis</span>
|
||
1996 Jul;124 Suppl:S1-9.
|
||
doi: 10.1016/0021-9150(96)05851-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8831910" target="_blank">8831910</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1600837">Dichloroacetate.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stacpoole PW,
|
||
Greene YJ</span><br />
|
||
<span class="medgenPMjournal">Diabetes Care</span>
|
||
1992 Jun;15(6):785-91.
|
||
doi: 10.2337/diacare.15.6.785.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1600837" target="_blank">1600837</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20cholesterol%20concentration%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (64)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37353908">PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Millán-de-Meer M,
|
||
Luque-Ramírez M,
|
||
Nattero-Chávez L,
|
||
Escobar-Morreale HF</span><br />
|
||
<span class="medgenPMjournal">Hum Reprod Update</span>
|
||
2023 Nov 2;29(6):741-772.
|
||
doi: 10.1093/humupd/dmad015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37353908" target="_blank">37353908</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34662439">Lipoprotein Z, a hepatotoxic lipoprotein, predicts outcome in alcohol-associated hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hu K,
|
||
Perez-Matos MC,
|
||
Argemi J,
|
||
Vilar-Gomez E,
|
||
Shalaurova I,
|
||
Bullitt E,
|
||
Landeen L,
|
||
Sugahara G,
|
||
Deng H,
|
||
Mathur K,
|
||
Tran S,
|
||
Cai H,
|
||
He H,
|
||
Yalcin Y,
|
||
Vieira Barbosa J,
|
||
Ventura-Cots M,
|
||
Marx K,
|
||
Gad AP,
|
||
Niezen S,
|
||
Izunza Barba S,
|
||
Ang LH,
|
||
Popov YV,
|
||
Fricker Z,
|
||
Lai M,
|
||
Curry M,
|
||
Afdhal N,
|
||
Szabo G,
|
||
Mukamal KJ,
|
||
Sanyal AJ,
|
||
Otvos JD,
|
||
Malik R,
|
||
Saito T,
|
||
Connelly MA,
|
||
Chalasani NP,
|
||
Bataller R,
|
||
Jiang ZG</span><br />
|
||
<span class="medgenPMjournal">Hepatology</span>
|
||
2022 Apr;75(4):968-982.
|
||
Epub 2021 Dec 7
|
||
doi: 10.1002/hep.32203.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34662439" target="_blank">34662439</a><a href="/pmc/articles/PMC9299888" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34043628">Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Varma VR,
|
||
Wang Y,
|
||
An Y,
|
||
Varma S,
|
||
Bilgel M,
|
||
Doshi J,
|
||
Legido-Quigley C,
|
||
Delgado JC,
|
||
Oommen AM,
|
||
Roberts JA,
|
||
Wong DF,
|
||
Davatzikos C,
|
||
Resnick SM,
|
||
Troncoso JC,
|
||
Pletnikova O,
|
||
O'Brien R,
|
||
Hak E,
|
||
Baak BN,
|
||
Pfeiffer R,
|
||
Baloni P,
|
||
Mohmoudiandehkordi S,
|
||
Nho K,
|
||
Kaddurah-Daouk R,
|
||
Bennett DA,
|
||
Gadalla SM,
|
||
Thambisetty M</span><br />
|
||
<span class="medgenPMjournal">PLoS Med</span>
|
||
2021 May;18(5):e1003615.
|
||
Epub 2021 May 27
|
||
doi: 10.1371/journal.pmed.1003615.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34043628" target="_blank">34043628</a><a href="/pmc/articles/PMC8158920" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33807271">High-Density Lipoproteins and the Kidney.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Strazzella A,
|
||
Ossoli A,
|
||
Calabresi L</span><br />
|
||
<span class="medgenPMjournal">Cells</span>
|
||
2021 Mar 31;10(4)
|
||
doi: 10.3390/cells10040764.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33807271" target="_blank">33807271</a><a href="/pmc/articles/PMC8065870" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12419478">Measurement issues related to lipoprotein heterogeneity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Otvos JD,
|
||
Jeyarajah EJ,
|
||
Cromwell WC</span><br />
|
||
<span class="medgenPMjournal">Am J Cardiol</span>
|
||
2002 Oct 17;90(8A):22i-29i.
|
||
doi: 10.1016/s0002-9149(02)02632-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12419478" target="_blank">12419478</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20cholesterol%20concentration%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (38)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37678743">Nuclear Magnetic Resonance-Based Metabolomics and Risk of CKD.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Geng TT,
|
||
Chen JX,
|
||
Lu Q,
|
||
Wang PL,
|
||
Xia PF,
|
||
Zhu K,
|
||
Li Y,
|
||
Guo KQ,
|
||
Yang K,
|
||
Liao YF,
|
||
Zhou YF,
|
||
Liu G,
|
||
Pan A</span><br />
|
||
<span class="medgenPMjournal">Am J Kidney Dis</span>
|
||
2024 Jan;83(1):9-17.
|
||
Epub 2023 Sep 9
|
||
doi: 10.1053/j.ajkd.2023.05.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37678743" target="_blank">37678743</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35411714">Profiling of circulating chromosome 21-encoded microRNAs, miR-155, and let-7c, in down syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pérez-Villarreal JM,
|
||
Aviña-Padilla K,
|
||
Beltrán-López E,
|
||
Guadrón-Llanos AM,
|
||
López-Bayghen E,
|
||
Magaña-Gómez J,
|
||
Meraz-Ríos MA,
|
||
Varela-Echavarría A,
|
||
Angulo-Rojo C</span><br />
|
||
<span class="medgenPMjournal">Mol Genet Genomic Med</span>
|
||
2022 Jun;10(6):e1938.
|
||
Epub 2022 Apr 12
|
||
doi: 10.1002/mgg3.1938.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35411714" target="_blank">35411714</a><a href="/pmc/articles/PMC9184673" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33807271">High-Density Lipoproteins and the Kidney.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Strazzella A,
|
||
Ossoli A,
|
||
Calabresi L</span><br />
|
||
<span class="medgenPMjournal">Cells</span>
|
||
2021 Mar 31;10(4)
|
||
doi: 10.3390/cells10040764.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33807271" target="_blank">33807271</a><a href="/pmc/articles/PMC8065870" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12700179">Androgens and coronary artery disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wu FC,
|
||
von Eckardstein A</span><br />
|
||
<span class="medgenPMjournal">Endocr Rev</span>
|
||
2003 Apr;24(2):183-217.
|
||
doi: 10.1210/er.2001-0025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12700179" target="_blank">12700179</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8035780">Pregnancy induced hypertension: a role for peroxidation in microvillus plasma membranes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cester N,
|
||
Staffolani R,
|
||
Rabini RA,
|
||
Magnanelli R,
|
||
Salvolini E,
|
||
Galassi R,
|
||
Mazzanti L,
|
||
Romanini C</span><br />
|
||
<span class="medgenPMjournal">Mol Cell Biochem</span>
|
||
1994 Feb 23;131(2):151-5.
|
||
doi: 10.1007/BF00925951.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8035780" target="_blank">8035780</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20cholesterol%20concentration%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (68)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37353908">PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Millán-de-Meer M,
|
||
Luque-Ramírez M,
|
||
Nattero-Chávez L,
|
||
Escobar-Morreale HF</span><br />
|
||
<span class="medgenPMjournal">Hum Reprod Update</span>
|
||
2023 Nov 2;29(6):741-772.
|
||
doi: 10.1093/humupd/dmad015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37353908" target="_blank">37353908</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31955966">Influence of Statins on Circulating Inflammatory Cytokines in Patients With Abnormal Glucose Homeostasis: A Meta-analysis of Data From Randomized Controlled Trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Milajerdi A,
|
||
Sadeghi A,
|
||
Mousavi SM,
|
||
Larijani B,
|
||
Esmaillzadeh A</span><br />
|
||
<span class="medgenPMjournal">Clin Ther</span>
|
||
2020 Feb;42(2):e13-e31.
|
||
Epub 2020 Jan 17
|
||
doi: 10.1016/j.clinthera.2019.12.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31955966" target="_blank">31955966</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22683130">Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tricco AC,
|
||
Ivers NM,
|
||
Grimshaw JM,
|
||
Moher D,
|
||
Turner L,
|
||
Galipeau J,
|
||
Halperin I,
|
||
Vachon B,
|
||
Ramsay T,
|
||
Manns B,
|
||
Tonelli M,
|
||
Shojania K</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2012 Jun 16;379(9833):2252-61.
|
||
Epub 2012 Jun 9
|
||
doi: 10.1016/S0140-6736(12)60480-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22683130" target="_blank">22683130</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20cholesterol%20concentration%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div></div>
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