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<!--
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UID=871143
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ConceptID=C4025614
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">EMG: chronic denervation signs</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>871143</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4025614</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0003444">HP:0003444</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">Evidence of chronic denervation on electromyography. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">EMG: chronic denervation signs</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/867380" ref="tree=MeSH" title="MedGen record for Abnormality of the musculature">Abnormality of the musculature</a></span><ul><li><span class="TLline"><a href="/medgen/868777" ref="tree=MeSH" title="MedGen record for Abnormal muscle physiology">Abnormal muscle physiology</a></span><ul><li><span class="TLline"><a href="/medgen/99199" ref="tree=MeSH" title="MedGen record for EMG abnormality">EMG abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867363" ref="tree=MeSH" title="MedGen record for EMG: neuropathic changes">EMG: neuropathic changes</a></span><ul><li><span class="matched_ds">EMG: chronic denervation signs</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_101816"><div><strong>Kugelberg-Welander disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>101816</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0152109</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Spinal muscular atrophy (SMA) is characterized by muscle weakness and atrophy resulting from progressive degeneration and irreversible loss of the anterior horn cells in the spinal cord (i.e., lower motor neurons) and the brain stem nuclei. The onset of weakness ranges from before birth to adulthood. The weakness is symmetric, proximal greater than distal, and progressive. Before the genetic basis of SMA was understood, it was classified into clinical subtypes based on maximum motor function achieved; however, it is now apparent that the phenotype of SMN1-associated SMA spans a continuum without clear delineation of subtypes. With supportive care only, poor weight gain with growth failure, restrictive lung disease, scoliosis, and joint contractures are common complications; however, newly available targeted treatment options are changing the natural history of the disease.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/101816">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_82852"><div><strong>Infantile neuroaxonal dystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82852</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0270724</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">PLA2G6-associated neurodegeneration (PLAN) comprises a continuum of three phenotypes with overlapping clinical and radiologic features: Infantile neuroaxonal dystrophy (INAD). Atypical neuroaxonal dystrophy (atypical NAD). PLA2G6-related dystonia-parkinsonism. INAD usually begins between ages six months and three years with psychomotor regression or delay, hypotonia, and progressive spastic tetraparesis. Many affected children never learn to walk or lose the ability shortly after attaining it. Strabismus, nystagmus, and optic atrophy are common. Disease progression is rapid, resulting in severe spasticity, progressive cognitive decline, and visual impairment. Many affected children do not survive beyond their first decade. Atypical NAD shows more phenotypic variability than INAD. In general, onset is in early childhood but can be as late as the end of the second decade. The presenting signs may be gait instability, ataxia, or speech delay and autistic features, which are sometimes the only evidence of disease for a year or more. Strabismus, nystagmus, and optic atrophy are common. Neuropsychiatric disturbances including impulsivity, poor attention span, hyperactivity, and emotional lability are also common. The course is fairly stable during early childhood and resembles static encephalopathy but is followed by neurologic deterioration between ages seven and 12 years. PLA2G6-related dystonia-parkinsonism has a variable age of onset, but most individuals present in early adulthood with gait disturbance or neuropsychiatric changes. Affected individuals consistently develop dystonia and parkinsonism (which may be accompanied by rapid cognitive decline) in their late teens to early twenties. Dystonia is most common in the hands and feet but may be more generalized. The most common features of parkinsonism in these individuals are bradykinesia, resting tremor, rigidity, and postural instability.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82852">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_162893"><div><strong>Agenesis of the corpus callosum with peripheral neuropathy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>162893</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0795950</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary motor and sensory neuropathy with agenesis of the corpus callosum (HMSN/ACC), a neurodevelopmental and neurodegenerative disorder, is characterized by severe progressive sensorimotor neuropathy with resulting hypotonia, areflexia, and amyotrophy, and by variable degrees of dysgenesis of the corpus callosum. Mild-to-severe intellectual disability and "psychotic episodes" during adolescence are observed. Sensory modalities are moderately to severely affected beginning in infancy. The average age of onset of walking is 3.8 years; the average age of loss of walking is 13.8 years; the average age of death is 33 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/162893">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_324826"><div><strong>Charcot-Marie-Tooth disease axonal type 2L</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>324826</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1837552</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Axonal Charcot-Marie-Tooth disease type 2L (CMT2L) is an autosomal dominant neuromuscular disorder characterized by muscle weakness and atrophy and sensory impairment of the distal lower and upper limbs resulting from a length-dependent axonal peripheral neuropathy. The lower limbs are predominantly affected, resulting in slowly progressive walking difficulties. Some individuals have involvement of the proximal lower limbs. Electrophysiologic studies are consistent with a axonal neuropathy, and muscle imaging shows muscle atrophy and fatty replacement in the lower limbs. Sural nerve biopsy shows loss of large myelinated fibers and abnormal axonal morphology (Tang et al., 2004; Nakhro et al., 2013). For a phenotypic description and a discussion of genetic heterogeneity of axonal CMT type 2, see CMT2A (118210).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/324826">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_349246"><div><strong>Amyotrophic lateral sclerosis type 2, juvenile</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>349246</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1859807</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">ALS2-related disorder involves retrograde degeneration of the upper motor neurons of the pyramidal tracts and comprises a clinical continuum of the following three phenotypes: Infantile ascending hereditary spastic paraplegia (IAHSP), characterized by onset of spasticity with increased reflexes and sustained clonus of the lower limbs within the first two years of life, progressive weakness and spasticity of the upper limbs by age seven to eight years, and wheelchair dependence in the second decade with progression toward severe spastic tetraparesis and a pseudobulbar syndrome caused by progressive cranial nerve involvement. Juvenile primary lateral sclerosis (JPLS), characterized by upper motor neuron findings of pseudobulbar palsy and spastic quadriplegia without dementia or cerebellar, extrapyramidal, or sensory signs. Juvenile amyotrophic lateral sclerosis (JALS or ALS2), characterized by onset between ages three and 20 years. All affected individuals show a spastic pseudobulbar syndrome (spasticity of speech and swallowing) together with spastic paraplegia. Some individuals are bedridden by age 12 to 50 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/349246">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_400593"><div><strong>Giant axonal neuropathy 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>400593</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1864695</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Giant axonal neuropathy-2 is an autosomal dominant peripheral axonal neuropathy characterized by onset of distal sensory impairment and lower extremity muscle weakness and atrophy after the second decade. Foot deformities may be present in childhood. More severely affected individuals may develop cardiomyopathy. Sural nerve biopsy shows giant axonal swelling with neurofilament accumulation (summary by Klein et al., 2014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/400593">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_854832"><div><strong>Neuronopathy, distal hereditary motor, type 2D</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854832</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3888271</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal dominant distal hereditary motor neuronopathy-6 (HMND6) is a neurologic disorder characterized by onset of slowly progressive distal lower limb weakness and atrophy between the second and fourth decades of life. Weakness usually begins in the calf muscles and later involves more proximal muscles. The severity is variable, and some patients have difficulty walking or running. Most also have upper limb involvement, particularly of the triceps and intrinsic hand muscles. Some patients may lose independent ambulation later in the disease course. Sensory impairment is typically not present, and cognition and bulbar function are normal (summary by Sumner et al., 2013). For a general phenotypic description and a discussion of genetic heterogeneity of autosomal dominant distal HMN (dHMN), see HMND1 (182960).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/854832">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1677426"><div><strong>Charcot-Marie-Tooth disease, axonal, type 2EE</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1677426</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5193076</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Charcot-Marie-Tooth disease type 2EE (CMT2EE) is an autosomal recessive sensorimotor peripheral axonal neuropathy with onset in the first or second decades of life. The disorder primarily affects the lower limbs and is slowly progressive, sometimes resulting in loss of ambulation, with later onset of upper limb involvement. There is significant distal muscle weakness and atrophy, usually with foot or hand deformities. Skeletal muscle biopsy shows findings of disturbed mitochondrial maintenance. Cognition is unaffected, and chronic liver disease is absent (summary by Baumann et al., 2019). For a phenotypic description and a discussion of genetic heterogeneity of axonal CMT type 2, see CMT2A (118210).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1677426">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1759760"><div><strong>Frontotemporal dementia and/or amyotrophic lateral sclerosis 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1759760</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436279</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Frontotemporal dementia and/or amyotrophic lateral sclerosis-6 (FTDALS6) is an autosomal dominant neurodegenerative disorder with highly variable manifestations. Some patients present in adulthood with progressive FTD, often classified as the 'behavioral variant,' which is characterized by reduced empathy, impulsive behavior, personality changes, and reduced verbal output. Other patients present with features of amyotrophic lateral sclerosis (ALS), which is a fatal neurodegenerative disease characterized by upper and lower motor neuron dysfunction resulting in rapidly progressive paralysis and death from respiratory failure. The pathologic hallmarks of this disease include pallor of the corticospinal tract due to loss of motor neurons (in ALS). In both ALS and FTD, there are ubiquitin-positive inclusions within surviving neurons as well as deposition of pathologic TDP43 (TARDBP; 605078) or p62 (SQSTM1; 601530) aggregates. Patients with a D395G mutation (601023.0014) have been shown to develop pathologic tau (MAPT; 157140) aggregates. Some patients with the disorder may have features of both diseases, and there is significant interfamilial and intrafamilial phenotypic variability (summary by Johnson et al., 2010; Wong et al., 2018; Al-Obeidi et al., 2018; Darwich et al., 2020). For a general phenotypic description and a discussion of genetic heterogeneity of FTDALS, see FTDALS1 (105550).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1759760">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1798903"><div><strong>Hypotonia, infantile, with psychomotor retardation and characteristic facies 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1798903</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5567480</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Infantile hypotonia with psychomotor retardation and characteristic facies-3 is a severe autosomal recessive neurodevelopmental disorder with onset at birth or in early infancy. Most affected individuals show very poor, if any, normal psychomotor development, poor speech, and inability to walk independently (summary by Bhoj et al., 2016). For a general phenotypic description and a discussion of genetic heterogeneity of infantile hypotonia with psychomotor retardation and characteristic facies, see IHPRF1 (615419).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1798903">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_162893" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Agenesis of the corpus callosum with peripheral neuropathy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_349246" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Amyotrophic lateral sclerosis type 2, juvenile</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_324826" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth disease axonal type 2L</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1677426" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth disease, axonal, type 2EE</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1759760" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Frontotemporal dementia and/or amyotrophic lateral sclerosis 6</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (10)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_400593" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Giant axonal neuropathy 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1798903" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypotonia, infantile, with psychomotor retardation and characteristic facies 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_82852" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Infantile neuroaxonal dystrophy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_101816" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Kugelberg-Welander disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_854832" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neuronopathy, distal hereditary motor, type 2D</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/20482606">EFNS guideline on the treatment of tension-type headache - report of an EFNS task force.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bendtsen L,
|
||
Evers S,
|
||
Linde M,
|
||
Mitsikostas DD,
|
||
Sandrini G,
|
||
Schoenen J;
|
||
EFNS</span><br />
|
||
<span class="medgenPMjournal">Eur J Neurol</span>
|
||
2010 Nov;17(11):1318-25.
|
||
doi: 10.1111/j.1468-1331.2010.03070.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20482606" target="_blank">20482606</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17257084">The management of cervical dystonia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ferreira JJ,
|
||
Costa J,
|
||
Coelho M,
|
||
Sampaio C</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Pharmacother</span>
|
||
2007 Feb;8(2):129-40.
|
||
doi: 10.1517/14656566.8.2.129.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17257084" target="_blank">17257084</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6993992">Spasticity: medical and surgical treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dimitrijevic MR,
|
||
Sherwood AM</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
1980 Jul;30(7 Pt 2):19-27.
|
||
doi: 10.1212/wnl.30.7_part_2.19.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6993992" target="_blank">6993992</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(emg%3A%20chronic%20denervation%20signs)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (8)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34284601">Ultrasound-guided diagnostic IPACK as a valuable tool in the management of a patient with soleal sling syndrome: a doubly rare case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Clendenen SR,
|
||
Ferreira-Dos-Santos G,
|
||
B Hurdle MF,
|
||
Tran J,
|
||
Agur AM,
|
||
Eldrige JS,
|
||
Murray PM</span><br />
|
||
<span class="medgenPMjournal">Pain Manag</span>
|
||
2022 Jan;12(1):5-12.
|
||
Epub 2021 Jul 21
|
||
doi: 10.2217/pmt-2020-0104.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34284601" target="_blank">34284601</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33265090">Possible implication of undescribed SMN1-SMN2 genotype in chronic EMG-pattern of SMA with transitory acute denervation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vitello GA,
|
||
Calì F,
|
||
Vinci M,
|
||
Scuderi C,
|
||
L'Episcopo F,
|
||
Musumeci A,
|
||
Musumeci SA,
|
||
Nicotera AG</span><br />
|
||
<span class="medgenPMjournal">J Musculoskelet Neuronal Interact</span>
|
||
2020 Dec 1;20(4):610-613.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33265090" target="_blank">33265090</a><a href="/pmc/articles/PMC7716687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32096875">Electrodiagnostic characteristics of upper lumbar stenosis: Discrepancy between neurological and structural levels.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Park JH,
|
||
Chung SG,
|
||
Kim K</span><br />
|
||
<span class="medgenPMjournal">Muscle Nerve</span>
|
||
2020 May;61(5):580-586.
|
||
Epub 2020 Mar 7
|
||
doi: 10.1002/mus.26844.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32096875" target="_blank">32096875</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30642740">A novel MFN2 mutation causes variable clinical severity in a multi-generational CMT2 family.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dankwa L,
|
||
Richardson J,
|
||
Motley WW,
|
||
Scavina M,
|
||
Courel S,
|
||
Bardakjian T,
|
||
Züchner S,
|
||
Scherer SS</span><br />
|
||
<span class="medgenPMjournal">Neuromuscul Disord</span>
|
||
2019 Feb;29(2):134-137.
|
||
Epub 2018 Dec 21
|
||
doi: 10.1016/j.nmd.2018.12.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30642740" target="_blank">30642740</a><a href="/pmc/articles/PMC6415944" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29859652">PLA2G6-associated neurodegeneration: Lessons from neurophysiological findings.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gitiaux C,
|
||
Kaminska A,
|
||
Boddaert N,
|
||
Barcia G,
|
||
Guéden S,
|
||
The Tich SN,
|
||
De Lonlay P,
|
||
Quijano-Roy S,
|
||
Hully M,
|
||
Péréon Y,
|
||
Desguerre I</span><br />
|
||
<span class="medgenPMjournal">Eur J Paediatr Neurol</span>
|
||
2018 Sep;22(5):854-861.
|
||
Epub 2018 May 22
|
||
doi: 10.1016/j.ejpn.2018.05.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29859652" target="_blank">29859652</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EMG%3A%20chronic%20denervation%20signs%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (90)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31277853">Normal and abnormal spontaneous activity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rubin DI</span><br />
|
||
<span class="medgenPMjournal">Handb Clin Neurol</span>
|
||
2019;160:257-279.
|
||
doi: 10.1016/B978-0-444-64032-1.00017-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31277853" target="_blank">31277853</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21600455">Complex regional pain syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah A,
|
||
Kirchner JS</span><br />
|
||
<span class="medgenPMjournal">Foot Ankle Clin</span>
|
||
2011 Jun;16(2):351-66.
|
||
doi: 10.1016/j.fcl.2011.03.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21600455" target="_blank">21600455</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20482606">EFNS guideline on the treatment of tension-type headache - report of an EFNS task force.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bendtsen L,
|
||
Evers S,
|
||
Linde M,
|
||
Mitsikostas DD,
|
||
Sandrini G,
|
||
Schoenen J;
|
||
EFNS</span><br />
|
||
<span class="medgenPMjournal">Eur J Neurol</span>
|
||
2010 Nov;17(11):1318-25.
|
||
doi: 10.1111/j.1468-1331.2010.03070.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20482606" target="_blank">20482606</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17257084">The management of cervical dystonia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ferreira JJ,
|
||
Costa J,
|
||
Coelho M,
|
||
Sampaio C</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Pharmacother</span>
|
||
2007 Feb;8(2):129-40.
|
||
doi: 10.1517/14656566.8.2.129.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17257084" target="_blank">17257084</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6153056">The neuropathy of abetalipoproteinemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miller RG,
|
||
Davis CJ,
|
||
Illingworth DR,
|
||
Bradley W</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
1980 Dec;30(12):1286-91.
|
||
doi: 10.1212/wnl.30.12.1286.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6153056" target="_blank">6153056</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EMG%3A%20chronic%20denervation%20signs%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (153)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34510092">Electromyography in Congenital Zika Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gouveia de Melo ACM,
|
||
van der Linden V,
|
||
Serpa SC,
|
||
Rolim Filho EL,
|
||
Lins OG</span><br />
|
||
<span class="medgenPMjournal">J Clin Neurophysiol</span>
|
||
2023 May 1;40(4):350-354.
|
||
Epub 2021 Sep 6
|
||
doi: 10.1097/WNP.0000000000000893.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34510092" target="_blank">34510092</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21600455">Complex regional pain syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah A,
|
||
Kirchner JS</span><br />
|
||
<span class="medgenPMjournal">Foot Ankle Clin</span>
|
||
2011 Jun;16(2):351-66.
|
||
doi: 10.1016/j.fcl.2011.03.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21600455" target="_blank">21600455</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20482606">EFNS guideline on the treatment of tension-type headache - report of an EFNS task force.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bendtsen L,
|
||
Evers S,
|
||
Linde M,
|
||
Mitsikostas DD,
|
||
Sandrini G,
|
||
Schoenen J;
|
||
EFNS</span><br />
|
||
<span class="medgenPMjournal">Eur J Neurol</span>
|
||
2010 Nov;17(11):1318-25.
|
||
doi: 10.1111/j.1468-1331.2010.03070.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20482606" target="_blank">20482606</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11838651">Complex regional pain syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rho RH,
|
||
Brewer RP,
|
||
Lamer TJ,
|
||
Wilson PR</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2002 Feb;77(2):174-80.
|
||
doi: 10.4065/77.2.174.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11838651" target="_blank">11838651</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4938133">Functional compensation in partially denervated muscles.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McComas AJ,
|
||
Sica RE,
|
||
Campbell MJ,
|
||
Upton AR</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
1971 Aug;34(4):453-60.
|
||
doi: 10.1136/jnnp.34.4.453.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4938133" target="_blank">4938133</a><a href="/pmc/articles/PMC493831" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EMG%3A%20chronic%20denervation%20signs%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (59)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35354563">Late adult-onset spinal muscular atrophy with lower extremity predominance (SMALED).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aziz I,
|
||
Davis M,
|
||
Liang C</span><br />
|
||
<span class="medgenPMjournal">BMJ Case Rep</span>
|
||
2022 Mar 30;15(3)
|
||
doi: 10.1136/bcr-2021-248297.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35354563" target="_blank">35354563</a><a href="/pmc/articles/PMC8968532" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31188475">Vagal stimulation and laryngeal electromyography for recurrent laryngeal reinnervation in children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Caloway CL,
|
||
Diercks GR,
|
||
Randolph G,
|
||
Hartnick CJ</span><br />
|
||
<span class="medgenPMjournal">Laryngoscope</span>
|
||
2020 Mar;130(3):747-751.
|
||
Epub 2019 Jun 12
|
||
doi: 10.1002/lary.28135.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31188475" target="_blank">31188475</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31277853">Normal and abnormal spontaneous activity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rubin DI</span><br />
|
||
<span class="medgenPMjournal">Handb Clin Neurol</span>
|
||
2019;160:257-279.
|
||
doi: 10.1016/B978-0-444-64032-1.00017-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31277853" target="_blank">31277853</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21636836">Potential of an electric prosthesis for dynamic facial reanimation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Griffin GR,
|
||
Kim JC</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Head Neck Surg</span>
|
||
2011 Sep;145(3):365-8.
|
||
Epub 2011 Jun 2
|
||
doi: 10.1177/0194599811406065.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21636836" target="_blank">21636836</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11191927">Electrodiagnosis of polyneuropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Johnsen B,
|
||
Fuglsang-Frederiksen A</span><br />
|
||
<span class="medgenPMjournal">Neurophysiol Clin</span>
|
||
2000 Dec;30(6):339-51.
|
||
doi: 10.1016/s0987-7053(00)00237-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11191927" target="_blank">11191927</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EMG%3A%20chronic%20denervation%20signs%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (49)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36183286">Correlation between clinical phenotype and electromyographic parameters in amyotrophic lateral sclerosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Colombo E,
|
||
Doretti A,
|
||
Scheveger F,
|
||
Maranzano A,
|
||
Pata G,
|
||
Gagliardi D,
|
||
Meneri M,
|
||
Messina S,
|
||
Verde F,
|
||
Morelli C,
|
||
Corti S,
|
||
Maderna L,
|
||
Silani V,
|
||
Ticozzi N</span><br />
|
||
<span class="medgenPMjournal">J Neurol</span>
|
||
2023 Jan;270(1):511-518.
|
||
Epub 2022 Oct 2
|
||
doi: 10.1007/s00415-022-11404-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36183286" target="_blank">36183286</a><a href="/pmc/articles/PMC9813173" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34232890">Functional Evaluation of Larynx Nerve Stimulator With EMG Acquisition Capability and Wireless Connectivity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Telyshev D,
|
||
Nesterenko I,
|
||
Bochkov A,
|
||
Malinina A,
|
||
Markov A,
|
||
Bordovsky S,
|
||
Polunin G,
|
||
Ananichuk A,
|
||
Reshetov I</span><br />
|
||
<span class="medgenPMjournal">IEEE Trans Biomed Circuits Syst</span>
|
||
2021 Jun;15(3):629-641.
|
||
Epub 2021 Aug 12
|
||
doi: 10.1109/TBCAS.2021.3094890.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34232890" target="_blank">34232890</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31188475">Vagal stimulation and laryngeal electromyography for recurrent laryngeal reinnervation in children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Caloway CL,
|
||
Diercks GR,
|
||
Randolph G,
|
||
Hartnick CJ</span><br />
|
||
<span class="medgenPMjournal">Laryngoscope</span>
|
||
2020 Mar;130(3):747-751.
|
||
Epub 2019 Jun 12
|
||
doi: 10.1002/lary.28135.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31188475" target="_blank">31188475</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24145758">Origin of fasciculations in amyotrophic lateral sclerosis and benign fasciculation syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Carvalho M,
|
||
Swash M</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2013 Dec;70(12):1562-5.
|
||
doi: 10.1001/jamaneurol.2013.4437.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24145758" target="_blank">24145758</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21636836">Potential of an electric prosthesis for dynamic facial reanimation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Griffin GR,
|
||
Kim JC</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Head Neck Surg</span>
|
||
2011 Sep;145(3):365-8.
|
||
Epub 2011 Jun 2
|
||
doi: 10.1177/0194599811406065.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21636836" target="_blank">21636836</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EMG%3A%20chronic%20denervation%20signs%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (63)</a></div></div>
|
||
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|
||
|
||
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38757474">Multifidus atrophy and/or dysfunction following lumbar radiofrequency ablation: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tieppo Francio V,
|
||
Glicksman M,
|
||
Leavitt L,
|
||
Gill B,
|
||
Shah A,
|
||
Westerhaus BD,
|
||
Lam CM,
|
||
D'Souza RS</span><br />
|
||
<span class="medgenPMjournal">PM R</span>
|
||
2024 Dec;16(12):1384-1394.
|
||
Epub 2024 May 16
|
||
doi: 10.1002/pmrj.13202.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38757474" target="_blank">38757474</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18206215">Focal myositis of the calf following S1 radiculopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gross R,
|
||
Degive C,
|
||
Dernis E,
|
||
Plat M,
|
||
Dubourg O,
|
||
Puéchal X</span><br />
|
||
<span class="medgenPMjournal">Semin Arthritis Rheum</span>
|
||
2008 Aug;38(1):20-7.
|
||
Epub 2008 Feb 21
|
||
doi: 10.1016/j.semarthrit.2007.09.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18206215" target="_blank">18206215</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22EMG%3A%20chronic%20denervation%20signs%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div></div>
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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