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UID=870491
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ConceptID=C4024938
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Segmental peripheral demyelination</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>870491</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4024938</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0007107">HP:0007107</a></td></tr>
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<div class="portlet_content ln">A loss of myelin from the internode regions along myelinated nerve fibers from segments of the peripheral nervous system. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Segmental peripheral demyelination</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868416" ref="tree=MeSH" title="MedGen record for Abnormal nervous system morphology">Abnormal nervous system morphology</a></span><ul><li><span class="TLline"><a href="/medgen/347527" ref="tree=MeSH" title="MedGen record for Abnormal myelination">Abnormal myelination</a></span><ul><li><span class="TLline"><a href="/medgen/871174" ref="tree=MeSH" title="MedGen record for Abnormal peripheral myelination">Abnormal peripheral myelination</a></span><ul><li><span class="TLline"><a href="/medgen/451074" ref="tree=MeSH" title="MedGen record for Peripheral demyelination">Peripheral demyelination</a></span><ul><li><span class="matched_ds">Segmental peripheral demyelination</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_338346"><div><strong>Charcot-Marie-Tooth disease dominant intermediate B</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>338346</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1847902</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Charcot-Marie-Tooth disease is a clinically and genetically heterogeneous disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Classification CMT neuropathy is subdivided into CMT1 (see 118200) and CMT2 (see 118210) types on the basis of electrophysiologic and neuropathologic criteria. CMT1, or hereditary motor and sensory neuropathy type I (HMSN I), is a demyelinating neuropathy, whereas CMT2, or HMSN II, is an axonal neuropathy. Most patients with CMT are classified as having CMT1 or CMT2 by use of a cut-off value of 38 m/s for the motor median nerve conduction velocity (NCV). However, in some families with CMT, patients have motor median NCVs ranging from 25 to 45 m/s. Families of this type were reported by Salisachs (1974) and Davis et al. (1978). Davis et al. (1978) proposed that this form be designated 'intermediate' CMT. Claeys et al. (2009) stated that some CMT families may have an even broader range of NCV than 25 to 45 m/s, with the lowest levels around 25 and the highest levels within the normal range (50+ m/s). They also suggested that the term 'intermediate' should not be used to describe a single NCV value, but rather the CMT subtype at the level of the family (e.g., in families with a range or combinations of NCV values). Berciano et al. (2017) provided a detailed review of the different forms of intermediate CMT, noting that diagnoses may be controversial because of variable classification issues. The authors presented an algorithm for the interpretation of electrophysiologic studies in CMT, and suggested that nerve conduction studies should be conducted on the upper arm (axilla to elbow). They noted that distal axonal degeneration can result in secondary myelination defects, which may cause significantly decreased motor NCV and CMAP values that may be misinterpreted. Genetic Heterogeneity of Autosomal Dominant Intermediate CMT In addition to CMTDIB, which is caused by mutation in the DNM2 gene, other forms of dominant intermediate CMT include CMTDIA (620378), mapped to chromosome 10q24-q25; CMTDIC (608323), caused by mutation in the YARS gene (603623) on chromosome 1p35; CMTDID (607791), caused by mutation in the MPZ gene (159440) on chromosome 1q22; CMTDIE with focal segmental glomerulosclerosis (CMTDIE; 614455), caused by mutation in the INF2 gene (610982) on chromosome 14q32; CMTDIF (615185), caused by mutation in the GNB4 gene (610863) on chromosome 3q26; and CMTDIG (617882), caused by mutation in the NEFL gene (162280) on chromosome 8p21.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/338346">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_347821"><div><strong>Charcot-Marie-Tooth disease type 4A</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>347821</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1859198</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">GDAP1-related hereditary motor and sensory neuropathy (GDAP1-HMSN) is a peripheral neuropathy (also known as a subtype of Charcot-Marie-Tooth disease) that typically affects the lower extremities earlier and more severely than the upper extremities. As the neuropathy progresses, the distal upper extremities also become severely affected. Proximal muscles can also become weak. Age at onset ranges from infancy to early childhood. In most cases, disease progression causes disabilities within the first or second decade of life. At the end of the second decade, most individuals are wheelchair bound. Disease progression varies considerably even within the same family. The neuropathy can be either of the demyelinating type with reduced nerve conduction velocities or the axonal type with normal nerve conduction velocities. Vocal cord paresis is common. Intelligence is normal. Life expectancy is usually normal, but on occasion may be reduced because of secondary complications.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/347821">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_356581"><div><strong>Charcot-Marie-Tooth disease type 4C</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>356581</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1866636</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">SH3TC2-related hereditary motor and sensory neuropathy (SH3TC2-HMSN) is a demyelinating neuropathy characterized by severe spine deformities (scoliosis or kyphoscoliosis) and foot deformities (pes cavus, pes planus, or pes valgus) that typically present in the first decade of life or early adolescence. Other findings can include cranial nerve involvement (most commonly tongue involvement, facial weakness/paralysis, hearing impairment, dysarthria) and respiratory problems.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/356581">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1794143"><div><strong>Charcot-Marie-Tooth Disease, axonal, type 2GG</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794143</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5561933</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Charcot-Marie-Tooth disease type 2GG (CMT2GG) is an autosomal dominant axonal peripheral neuropathy characterized by slowly progressive distal muscle weakness and atrophy primarily affecting the lower limbs and causing difficulty walking. The onset is usually in adulthood, although rare patients may have mild symptoms from childhood. Some individuals may also have involvement of the hands. Although most patients have hypo- or areflexia at the ankles, distal sensory impairment is not always present, indicating a spectrum of disease encompassing both distal hereditary neuropathy and axonal CMT. Electrophysiologic studies are consistent with a axonal process (summary by Mendoza-Ferreira et al., 2020). For a discussion of genetic heterogeneity of axonal CMT, see CMT2A1 (118210).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1794143">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_338346" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth disease dominant intermediate B</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_347821" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth disease type 4A</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_356581" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth disease type 4C</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794143" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Charcot-Marie-Tooth Disease, axonal, type 2GG</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37272673">Autoimmune nodo-paranodopathies 10 years later: Clinical features, pathophysiology and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Uncini A</span><br />
|
||
<span class="medgenPMjournal">J Peripher Nerv Syst</span>
|
||
2023 Jul;28 Suppl 3:S23-S35.
|
||
doi: 10.1111/jns.12569.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37272673" target="_blank">37272673</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29866282">History, Diagnosis, and Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dyck PJB,
|
||
Tracy JA</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2018 Jun;93(6):777-793.
|
||
doi: 10.1016/j.mayocp.2018.03.026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29866282" target="_blank">29866282</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25424435">Different electrophysiological profiles and treatment response in 'typical' and 'atypical' chronic inflammatory demyelinating polyneuropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kuwabara S,
|
||
Isose S,
|
||
Mori M,
|
||
Mitsuma S,
|
||
Sawai S,
|
||
Beppu M,
|
||
Sekiguchi Y,
|
||
Misawa S</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
2015 Oct;86(10):1054-9.
|
||
Epub 2014 Nov 25
|
||
doi: 10.1136/jnnp-2014-308452.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25424435" target="_blank">25424435</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(segmental%20peripheral%20demyelination)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (9)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35611446">Acute nitrous oxide-induced neuropathy mimicking Guillain-Barré syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Qin X,
|
||
Kang L,
|
||
Liu X,
|
||
Jin J,
|
||
Hu F,
|
||
Lu W,
|
||
Deng Y,
|
||
Chen QY,
|
||
Dang J</span><br />
|
||
<span class="medgenPMjournal">J Peripher Nerv Syst</span>
|
||
2022 Sep;27(3):189-196.
|
||
Epub 2022 Jun 7
|
||
doi: 10.1111/jns.12503.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35611446" target="_blank">35611446</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32022288">Semi-automated volumetry of MRI serves as a biomarker in neuromuscular patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Müller M,
|
||
Dohrn MF,
|
||
Romanzetti S,
|
||
Gadermayr M,
|
||
Reetz K,
|
||
Krämer NA,
|
||
Kuhl C,
|
||
Schulz JB,
|
||
Gess B</span><br />
|
||
<span class="medgenPMjournal">Muscle Nerve</span>
|
||
2020 May;61(5):600-607.
|
||
Epub 2020 Feb 17
|
||
doi: 10.1002/mus.26827.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32022288" target="_blank">32022288</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25432810">Mechanisms of nerve injury in leprosy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Scollard DM,
|
||
Truman RW,
|
||
Ebenezer GJ</span><br />
|
||
<span class="medgenPMjournal">Clin Dermatol</span>
|
||
2015 Jan-Feb;33(1):46-54.
|
||
doi: 10.1016/j.clindermatol.2014.07.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25432810" target="_blank">25432810</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8430694">Linkage localization of X-linked Charcot-Marie-Tooth disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bergoffen J,
|
||
Trofatter J,
|
||
Pericak-Vance MA,
|
||
Haines JL,
|
||
Chance PF,
|
||
Fischbeck KH</span><br />
|
||
<span class="medgenPMjournal">Am J Hum Genet</span>
|
||
1993 Feb;52(2):312-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8430694" target="_blank">8430694</a><a href="/pmc/articles/PMC1682189" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8215977">Charcot-Marie-Tooth syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chance PF,
|
||
Pleasure D</span><br />
|
||
<span class="medgenPMjournal">Arch Neurol</span>
|
||
1993 Nov;50(11):1180-4.
|
||
doi: 10.1001/archneur.1993.00540110060006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8215977" target="_blank">8215977</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Segmental%20peripheral%20demyelination%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (107)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37272673">Autoimmune nodo-paranodopathies 10 years later: Clinical features, pathophysiology and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Uncini A</span><br />
|
||
<span class="medgenPMjournal">J Peripher Nerv Syst</span>
|
||
2023 Jul;28 Suppl 3:S23-S35.
|
||
doi: 10.1111/jns.12569.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37272673" target="_blank">37272673</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35611446">Acute nitrous oxide-induced neuropathy mimicking Guillain-Barré syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Qin X,
|
||
Kang L,
|
||
Liu X,
|
||
Jin J,
|
||
Hu F,
|
||
Lu W,
|
||
Deng Y,
|
||
Chen QY,
|
||
Dang J</span><br />
|
||
<span class="medgenPMjournal">J Peripher Nerv Syst</span>
|
||
2022 Sep;27(3):189-196.
|
||
Epub 2022 Jun 7
|
||
doi: 10.1111/jns.12503.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35611446" target="_blank">35611446</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33320867">Congenital Zika syndrome: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Freitas DA,
|
||
Souza-Santos R,
|
||
Carvalho LMA,
|
||
Barros WB,
|
||
Neves LM,
|
||
Brasil P,
|
||
Wakimoto MD</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2020;15(12):e0242367.
|
||
Epub 2020 Dec 15
|
||
doi: 10.1371/journal.pone.0242367.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33320867" target="_blank">33320867</a><a href="/pmc/articles/PMC7737899" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30400213">Clinical Features of Varicella-Zoster Virus Infection.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kennedy PGE,
|
||
Gershon AA</span><br />
|
||
<span class="medgenPMjournal">Viruses</span>
|
||
2018 Nov 2;10(11)
|
||
doi: 10.3390/v10110609.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30400213" target="_blank">30400213</a><a href="/pmc/articles/PMC6266119" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8840469">The trigeminal nerve.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nemzek WR</span><br />
|
||
<span class="medgenPMjournal">Top Magn Reson Imaging</span>
|
||
1996 Jun;8(3):132-54.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8840469" target="_blank">8840469</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Segmental%20peripheral%20demyelination%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (200)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35737187">Chronic inflammatory demyelinating polyradiculoneuropathy concomitant with nephropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hu N,
|
||
Niu J,
|
||
Liu M</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2022 Oct;43(10):5885-5898.
|
||
Epub 2022 Jun 23
|
||
doi: 10.1007/s10072-022-06215-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35737187" target="_blank">35737187</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35611446">Acute nitrous oxide-induced neuropathy mimicking Guillain-Barré syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Qin X,
|
||
Kang L,
|
||
Liu X,
|
||
Jin J,
|
||
Hu F,
|
||
Lu W,
|
||
Deng Y,
|
||
Chen QY,
|
||
Dang J</span><br />
|
||
<span class="medgenPMjournal">J Peripher Nerv Syst</span>
|
||
2022 Sep;27(3):189-196.
|
||
Epub 2022 Jun 7
|
||
doi: 10.1111/jns.12503.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35611446" target="_blank">35611446</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25742897">Immune-mediated neuropathy with Epstein-Barr virus-positive T-cell lymphoproliferative disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hattori T,
|
||
Arai A,
|
||
Yokota T,
|
||
Imadome K,
|
||
Tomimitsu H,
|
||
Miura O,
|
||
Mizusawa H</span><br />
|
||
<span class="medgenPMjournal">Intern Med</span>
|
||
2015;54(1):69-73.
|
||
Epub 2015 Jan 1
|
||
doi: 10.2169/internalmedicine.54.3173.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25742897" target="_blank">25742897</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12499464">Diagnosis of CIDP.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Latov N</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
2002 Dec 24;59(12 Suppl 6):S2-6.
|
||
doi: 10.1212/wnl.59.12_suppl_6.s2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12499464" target="_blank">12499464</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/772918">Abnormalities of bladder innervation in diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Andersen JT,
|
||
Bradley WE</span><br />
|
||
<span class="medgenPMjournal">Urology</span>
|
||
1976 Apr;7(4):442-8.
|
||
doi: 10.1016/0090-4295(76)90266-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/772918" target="_blank">772918</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Segmental%20peripheral%20demyelination%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (71)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/25742897">Immune-mediated neuropathy with Epstein-Barr virus-positive T-cell lymphoproliferative disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hattori T,
|
||
Arai A,
|
||
Yokota T,
|
||
Imadome K,
|
||
Tomimitsu H,
|
||
Miura O,
|
||
Mizusawa H</span><br />
|
||
<span class="medgenPMjournal">Intern Med</span>
|
||
2015;54(1):69-73.
|
||
Epub 2015 Jan 1
|
||
doi: 10.2169/internalmedicine.54.3173.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25742897" target="_blank">25742897</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25432810">Mechanisms of nerve injury in leprosy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Scollard DM,
|
||
Truman RW,
|
||
Ebenezer GJ</span><br />
|
||
<span class="medgenPMjournal">Clin Dermatol</span>
|
||
2015 Jan-Feb;33(1):46-54.
|
||
doi: 10.1016/j.clindermatol.2014.07.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25432810" target="_blank">25432810</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15742374">Onset and course of chronic inflammatory demyelinating polyneuropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mygland A,
|
||
Monstad P,
|
||
Vedeler C</span><br />
|
||
<span class="medgenPMjournal">Muscle Nerve</span>
|
||
2005 May;31(5):589-93.
|
||
doi: 10.1002/mus.20297.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15742374" target="_blank">15742374</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8840469">The trigeminal nerve.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nemzek WR</span><br />
|
||
<span class="medgenPMjournal">Top Magn Reson Imaging</span>
|
||
1996 Jun;8(3):132-54.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8840469" target="_blank">8840469</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/187157">Axonal degeneration in beriberi neuropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Takahashi K,
|
||
Nakamura H</span><br />
|
||
<span class="medgenPMjournal">Arch Neurol</span>
|
||
1976 Dec;33(12):836-41.
|
||
doi: 10.1001/archneur.1976.00500120040006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/187157" target="_blank">187157</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Segmental%20peripheral%20demyelination%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (81)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35737187">Chronic inflammatory demyelinating polyradiculoneuropathy concomitant with nephropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hu N,
|
||
Niu J,
|
||
Liu M</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2022 Oct;43(10):5885-5898.
|
||
Epub 2022 Jun 23
|
||
doi: 10.1007/s10072-022-06215-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35737187" target="_blank">35737187</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8840469">The trigeminal nerve.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nemzek WR</span><br />
|
||
<span class="medgenPMjournal">Top Magn Reson Imaging</span>
|
||
1996 Jun;8(3):132-54.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8840469" target="_blank">8840469</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8430694">Linkage localization of X-linked Charcot-Marie-Tooth disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bergoffen J,
|
||
Trofatter J,
|
||
Pericak-Vance MA,
|
||
Haines JL,
|
||
Chance PF,
|
||
Fischbeck KH</span><br />
|
||
<span class="medgenPMjournal">Am J Hum Genet</span>
|
||
1993 Feb;52(2):312-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8430694" target="_blank">8430694</a><a href="/pmc/articles/PMC1682189" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/185339">Recessive hereditary sensory neuropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jedrzejowska H,
|
||
Milczarek H</span><br />
|
||
<span class="medgenPMjournal">J Neurol Sci</span>
|
||
1976 Oct;29(2-4):371-87.
|
||
doi: 10.1016/0022-510x(76)90186-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/185339" target="_blank">185339</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4168052">Peripheral neuropathy of metachromatic leucodystrophy: observations on segmental demyelination and remyelination and the intracellular distribution of sulphatide.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dayan AD</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
1967 Aug;30(4):311-8.
|
||
doi: 10.1136/jnnp.30.4.311.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4168052" target="_blank">4168052</a><a href="/pmc/articles/PMC496191" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Segmental%20peripheral%20demyelination%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (116)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/33320867">Congenital Zika syndrome: A systematic review.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Freitas DA,
|
||
Souza-Santos R,
|
||
Carvalho LMA,
|
||
Barros WB,
|
||
Neves LM,
|
||
Brasil P,
|
||
Wakimoto MD</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2020;15(12):e0242367.
|
||
Epub 2020 Dec 15
|
||
doi: 10.1371/journal.pone.0242367.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33320867" target="_blank">33320867</a><a href="/pmc/articles/PMC7737899" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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