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<!--
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||
UID=7480
|
||
ConceptID=C0024904
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Mastoiditis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>7480</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0024904</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Mastoiditides</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Mastoiditis (52404001)</td></tr>
|
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000265">HP:0000265</a></td></tr>
|
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<tr><td>Monarch Initiative:</td>
|
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<td><a href="https://monarchinitiative.org/disease/MONDO:0000748" target="_blank">MONDO:0000748</a></td></tr>
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<div class="portlet_content ln">Inflammation of the mucosal lining of the mastoid antrum and mastoid air cell system of the mastoid process. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Mastoiditis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/867418" ref="tree=MeSH" title="MedGen record for Abnormality of the skeletal system">Abnormality of the skeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/868760" ref="tree=MeSH" title="MedGen record for Abnormal skeletal morphology">Abnormal skeletal morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892434" ref="tree=MeSH" title="MedGen record for Abnormal axial skeleton morphology">Abnormal axial skeleton morphology</a></span><ul><li><span class="TLline"><a href="/medgen/488801" ref="tree=MeSH" title="MedGen record for Abnormal skull morphology">Abnormal skull morphology</a></span><ul><li><span class="TLline"><a href="/medgen/871376" ref="tree=MeSH" title="MedGen record for Abnormal mastoid morphology">Abnormal mastoid morphology</a></span><ul><li><span class="matched_ds">Mastoiditis</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_140771"><div><strong>Microcephaly, normal intelligence and immunodeficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>140771</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0398791</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Nijmegen breakage syndrome (NBS) is characterized by progressive microcephaly, early growth deficiency that improves with age, recurrent respiratory infections, an increased risk for malignancy (primarily lymphoma), and premature ovarian failure in females. Developmental milestones are attained at the usual time during the first year; however, borderline delays in development and hyperactivity may be observed in early childhood. Intellectual abilities tend to decline over time. Recurrent pneumonia and bronchitis may result in respiratory failure and early death. Other reported malignancies include solid tumors (e.g., medulloblastoma, glioma, rhabdomyosarcoma).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/140771">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_321935"><div><strong>Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>321935</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1832322</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Severe combined immunodeficiency refers to a genetically and clinically heterogeneous group of disorders with defective cellular and humoral immune function. Patients with SCID present in infancy with recurrent, persistent infections by opportunistic organisms, including Candida albicans, Pneumocystis carinii, and cytomegalovirus, among many others. Laboratory analysis shows profound lymphopenia with diminished or absent immunoglobulins. The common characteristic of all types of SCID is absence of T cell-mediated cellular immunity due to a defect in T-cell development. Without treatment, patients usually die within the first year of life. The overall prevalence of all types of SCID is approximately 1 in 75,000 births (Fischer et al., 1997; Buckley, 2004). Genetic Heterogeneity of SCID SCID can be divided into 2 main classes: those with B lymphocytes (B+ SCID) and those without (B- SCID). Presence or absence of NK cells is variable within these groups. The most common form of SCID is X-linked T-, B+, NK- SCID (SCIDX1; 300400) caused by mutation in the IL2RG gene (308380) on chromosome Xq13.1. Autosomal recessive SCID includes T-, B-, NK+ SCID, caused by mutation in the RAG1 and RAG2 genes on 11p13; T-, B+, NK- SCID (600802), caused by mutation in the JAK3 gene (600173) on 19p13; T-, B+, NK+ SCID (IMD104; 608971), caused by mutation in the IL7R gene (146661) on 5p13; T-, B+, NK+ SCID (IMD105; 619924), caused by mutation in the CD45 gene (PTPRC; 151460) on 1q31-q32; T-, B+, NK+ SCID (IMD19; 615617), caused by mutation in the CD3D gene (186790) on 11q23; T-, B-, NK- SCID (102700) caused by mutation in the ADA (608958) gene on 20q13; and T-, B-, NK+ SCID with sensitivity to ionizing radiation (602450), caused by mutation in the Artemis gene (DCLRE1C; 605988) on 10p13 (Kalman et al., 2004); T-, B+, NK+ SCID with intellectual disability, spasticity, and craniofacial abnormalities (IMD49; 617237), caused by mutation in the BCL11B gene (606558) on 14q32; and T-, B-, NK+ SCID with microcephaly, growth retardation, and sensitivity to ionizing radiation (IMD124; 611291), caused by mutation in the NHEJ1 gene (611290) on 2q35. Approximately 20 to 30% of all SCID patients are T-, B-, NK+, and approximately half of these patients have mutations in the RAG1 or RAG2 genes (Schwarz et al., 1996; Fischer et al., 1997).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/321935">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_327093"><div><strong>Hyperostosis cranialis interna</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>327093</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1840404</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyperostosis cranialis interna (HCIN) is a bone disorder characterized by endosteal hyperostosis and osteosclerosis of the calvaria and the skull base. The progressive bone overgrowth causes entrapment and dysfunction of cranial nerves I, II, V, VII, and VIII (Waterval et al., 2010).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/327093">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_815913"><div><strong>Combined immunodeficiency due to MALT1 deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>815913</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3809583</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Combined immunodeficiency due to MALT1 deficiency is a rare, genetic form of primary immunodeficiency characterized by growth retardation, early recurrent pulmonary infections leading to bronchiectasis, inflammatory gastrointestinal disease, and other symptoms, such as rash, dermatitis, skin infections.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/815913">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1782278"><div><strong>Otofaciocervical syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1782278</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5442121</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Otofaciocervical syndrome-2 with T-cell deficiency (OTFCS2) is a rare disorder characterized by facial anomalies, cup-shaped low-set ears, preauricular fistulas, hearing loss, branchial defects, skeletal anomalies including vertebral defects, low-set clavicles, winged scapulae, sloping shoulders, and mild intellectual disability (summary by Pohl et al., 2013). Patients have been reported who also exhibit altered thymus development with T-cell immunodeficiency and recurrent, sometimes fatal, infections (Paganini et al., 2017; Yamazaki et al., 2020). For a discussion of genetic heterogeneity of otofaciocervical syndrome, see OTFCS1 (166780).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1782278">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1785772"><div><strong>Immunodeficiency 78 with autoimmunity and developmental delay</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1785772</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543159</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-78 with autoimmunity and developmental delay (IMD78) is an autosomal recessive systemic disorder characterized by onset of symptoms in early childhood. Affected individuals present with features of immune deficiency, such as recurrent sinopulmonary or skin infections, as well as autoimmunity, including autoimmune cytopenias, hemolytic anemia, and thrombocytopenia. Autoimmune hepatitis or thyroid disease and central nervous system vasculitis with stroke may also occur. There is increased susceptibility to bacterial, viral, and fungal infections. Laboratory studies show lymphopenia with advanced differentiation and premature senescence of CD8+ T cells and B cells; some patients may have hypergammaglobulinemia. The findings indicate immune dysregulation. Patients also have global developmental delay with speech delay and variable intellectual disability. Many patients die prematurely, but successful hematopoietic bone marrow transplant may be curative (summary by Lu et al., 2014 and Atallah et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1785772">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1840213"><div><strong>Autoinflammatory disease, multisystem, with immune dysregulation, X-linked</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1840213</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5829577</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">X-linked multisystem autoinflammatory disease with immune dysregulation (ADMIDX) is an X-linked recessive disorder with onset of symptoms in infancy or early childhood. Affected individuals may present with variable cytopenias, including anemia, thrombocytopenia, neutropenia, lymphopenia, or hypogammaglobulinemia, and systemic or organ-specific autoinflammatory manifestations. These include skin lesions, panniculitis, inflammatory bowel disease, pulmonary disease, or arthritis associated with recurrent fever, leukocytosis, lymphoproliferation, and hepatosplenomegaly in the absence of an infectious agent. Some patients have circulating autoantibodies that underlie the cytopenias or systemic features, whereas others do not have circulating autoantibodies. In addition, some patients have recurrent infections, whereas others do not show signs of an immunodeficiency. Laboratory studies are consistent with immune dysregulation, including altered B-cell subsets and variably elevated proinflammatory cytokines. Detailed functional studies of platelets, red cells, and T lymphocytes suggest that abnormal actin cytoskeleton remodeling is a basic defect, indicating that this disorder can be classified as an immune-related actinopathy. Severe complications of the disease may result in death in childhood (Boussard et al., 2023; Block et al., 2023).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1840213">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1840213" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autoinflammatory disease, multisystem, with immune dysregulation, X-linked</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_815913" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Combined immunodeficiency due to MALT1 deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_327093" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyperostosis cranialis interna</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1785772" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 78 with autoimmunity and developmental delay</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_140771" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Microcephaly, normal intelligence and immunodeficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1782278" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Otofaciocervical syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_321935" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37730165">Antimicrobial treatment of ENT infections.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cohen R,
|
||
Madhi F,
|
||
Thollot F,
|
||
Hau I,
|
||
Vie le Sage F,
|
||
Lemaître C,
|
||
Magendie C,
|
||
Werner A,
|
||
Gelbert N,
|
||
Cohen JF,
|
||
Couloigner V</span><br />
|
||
<span class="medgenPMjournal">Infect Dis Now</span>
|
||
2023 Nov;53(8S):104785.
|
||
Epub 2023 Sep 18
|
||
doi: 10.1016/j.idnow.2023.104785.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37730165" target="_blank">37730165</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28372534">Panel 7: Otitis Media: Treatment and Complications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schilder AG,
|
||
Marom T,
|
||
Bhutta MF,
|
||
Casselbrant ML,
|
||
Coates H,
|
||
Gisselsson-Solén M,
|
||
Hall AJ,
|
||
Marchisio P,
|
||
Ruohola A,
|
||
Venekamp RP,
|
||
Mandel EM</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Head Neck Surg</span>
|
||
2017 Apr;156(4_suppl):S88-S105.
|
||
doi: 10.1177/0194599816633697.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28372534" target="_blank">28372534</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20347664">Otomycosis: Diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vennewald I,
|
||
Klemm E</span><br />
|
||
<span class="medgenPMjournal">Clin Dermatol</span>
|
||
2010 Mar 4;28(2):202-11.
|
||
doi: 10.1016/j.clindermatol.2009.12.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20347664" target="_blank">20347664</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22mastoiditis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (105)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37730165">Antimicrobial treatment of ENT infections.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cohen R,
|
||
Madhi F,
|
||
Thollot F,
|
||
Hau I,
|
||
Vie le Sage F,
|
||
Lemaître C,
|
||
Magendie C,
|
||
Werner A,
|
||
Gelbert N,
|
||
Cohen JF,
|
||
Couloigner V</span><br />
|
||
<span class="medgenPMjournal">Infect Dis Now</span>
|
||
2023 Nov;53(8S):104785.
|
||
Epub 2023 Sep 18
|
||
doi: 10.1016/j.idnow.2023.104785.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37730165" target="_blank">37730165</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32073562">Acute mastoiditis in children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cassano P,
|
||
Ciprandi G,
|
||
Passali D</span><br />
|
||
<span class="medgenPMjournal">Acta Biomed</span>
|
||
2020 Feb 17;91(1-S):54-59.
|
||
doi: 10.23750/abm.v91i1-S.9259.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32073562" target="_blank">32073562</a><a href="/pmc/articles/PMC7947742" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28372534">Panel 7: Otitis Media: Treatment and Complications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schilder AG,
|
||
Marom T,
|
||
Bhutta MF,
|
||
Casselbrant ML,
|
||
Coates H,
|
||
Gisselsson-Solén M,
|
||
Hall AJ,
|
||
Marchisio P,
|
||
Ruohola A,
|
||
Venekamp RP,
|
||
Mandel EM</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Head Neck Surg</span>
|
||
2017 Apr;156(4_suppl):S88-S105.
|
||
doi: 10.1177/0194599816633697.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28372534" target="_blank">28372534</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27895000">Severe Acute Otitis Media and Acute Mastoiditis in Adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Laulajainen Hongisto A,
|
||
Jero J,
|
||
Markkola A,
|
||
Saat R,
|
||
Aarnisalo AA</span><br />
|
||
<span class="medgenPMjournal">J Int Adv Otol</span>
|
||
2016 Dec;12(3):224-230.
|
||
Epub 2016 Nov 28
|
||
doi: 10.5152/iao.2016.2620.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27895000" target="_blank">27895000</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19487433">Mastoiditis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Anderson KJ</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
2009 Jun;30(6):233-4.
|
||
doi: 10.1542/pir.30-6-233.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19487433" target="_blank">19487433</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mastoiditis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (596)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39217116">Mastoiditis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Carter L,
|
||
Callon W</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
2024 Sep 1;45(9):540-542.
|
||
doi: 10.1542/pir.2023-006249.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39217116" target="_blank">39217116</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32841094">Mastoiditis Masquerade.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Keidar E,
|
||
Bowers I,
|
||
Sargent E</span><br />
|
||
<span class="medgenPMjournal">Ear Nose Throat J</span>
|
||
2022 May;101(4):221-223.
|
||
Epub 2020 Aug 25
|
||
doi: 10.1177/0145561320950493.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32841094" target="_blank">32841094</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29716974">Mastoiditis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kynion R</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
2018 May;39(5):267-269.
|
||
doi: 10.1542/pir.2017-0128.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29716974" target="_blank">29716974</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28879826">Management of paediatric acute mastoiditis: systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Loh R,
|
||
Phua M,
|
||
Shaw CL</span><br />
|
||
<span class="medgenPMjournal">J Laryngol Otol</span>
|
||
2018 Feb;132(2):96-104.
|
||
Epub 2017 Sep 7
|
||
doi: 10.1017/S0022215117001840.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28879826" target="_blank">28879826</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24488833">Mastoiditis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bunik M</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
2014 Feb;35(2):94-5; discussion 94-5.
|
||
doi: 10.1542/pir.35-2-94.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24488833" target="_blank">24488833</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mastoiditis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (946)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39277503">Cochlear Implant Infections.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Antonelli PJ</span><br />
|
||
<span class="medgenPMjournal">Infect Dis Clin North Am</span>
|
||
2024 Dec;38(4):777-793.
|
||
Epub 2024 Sep 13
|
||
doi: 10.1016/j.idc.2024.07.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39277503" target="_blank">39277503</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/39217116">Mastoiditis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Carter L,
|
||
Callon W</span><br />
|
||
<span class="medgenPMjournal">Pediatr Rev</span>
|
||
2024 Sep 1;45(9):540-542.
|
||
doi: 10.1542/pir.2023-006249.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39217116" target="_blank">39217116</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32073562">Acute mastoiditis in children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cassano P,
|
||
Ciprandi G,
|
||
Passali D</span><br />
|
||
<span class="medgenPMjournal">Acta Biomed</span>
|
||
2020 Feb 17;91(1-S):54-59.
|
||
doi: 10.23750/abm.v91i1-S.9259.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32073562" target="_blank">32073562</a><a href="/pmc/articles/PMC7947742" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28879826">Management of paediatric acute mastoiditis: systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Loh R,
|
||
Phua M,
|
||
Shaw CL</span><br />
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<span class="medgenPMjournal">J Laryngol Otol</span>
|
||
2018 Feb;132(2):96-104.
|
||
Epub 2017 Sep 7
|
||
doi: 10.1017/S0022215117001840.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28879826" target="_blank">28879826</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23601480">Earache.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Conover K</span><br />
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<span class="medgenPMjournal">Emerg Med Clin North Am</span>
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2013 May;31(2):413-42.
|
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doi: 10.1016/j.emc.2013.02.001.
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<span class="bold">PMID: </span><a href="/pubmed/23601480" target="_blank">23601480</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mastoiditis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (634)</a></div><h3 class="subhead">Prognosis</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/37062439">Hypertrophic pachymeningitis in ANCA-associated vasculitis: Clinical and immunopathological features and insights.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Shimojima Y,
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Sekijima Y</span><br />
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<span class="medgenPMjournal">Autoimmun Rev</span>
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2023 Jun;22(6):103338.
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Epub 2023 Apr 14
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doi: 10.1016/j.autrev.2023.103338.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37062439" target="_blank">37062439</a></div>
|
||
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||
<div class="nl"><a target="_blank" href="/pubmed/32073562">Acute mastoiditis in children.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Cassano P,
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Ciprandi G,
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Passali D</span><br />
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<span class="medgenPMjournal">Acta Biomed</span>
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2020 Feb 17;91(1-S):54-59.
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doi: 10.23750/abm.v91i1-S.9259.
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<span class="bold">PMID: </span><a href="/pubmed/32073562" target="_blank">32073562</a><a href="/pmc/articles/PMC7947742" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/19487433">Mastoiditis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Anderson KJ</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/19487433" target="_blank">19487433</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/8484946">Actinomycosis otomastoiditis.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Tarabichi M,
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<span class="bold">PMID: </span><a href="/pubmed/8484946" target="_blank">8484946</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/6492966">Otitic hydrocephalus.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Lenz RP,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mastoiditis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (364)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37062439">Hypertrophic pachymeningitis in ANCA-associated vasculitis: Clinical and immunopathological features and insights.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shimojima Y,
|
||
Sekijima Y</span><br />
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||
<span class="medgenPMjournal">Autoimmun Rev</span>
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||
2023 Jun;22(6):103338.
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||
Epub 2023 Apr 14
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||
doi: 10.1016/j.autrev.2023.103338.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37062439" target="_blank">37062439</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36254655">Paediatric otogenic sinus venous thrombosis: the role of Fusobacterium necrophorum.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yosefof E,
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Hilly O,
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Sokolov M,
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Raveh E,
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Yacobovich J,
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Ulanovski D</span><br />
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<span class="medgenPMjournal">Acta Otorhinolaryngol Ital</span>
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2022 Aug;42(4):388-394.
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doi: 10.14639/0392-100X-N1835.
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<span class="bold">PMID: </span><a href="/pubmed/36254655" target="_blank">36254655</a><a href="/pmc/articles/PMC9577686" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28904032">Antibiotic therapy for children with acute otitis media.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Sakulchit T,
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||
Goldman RD</span><br />
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<span class="medgenPMjournal">Can Fam Physician</span>
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2017 Sep;63(9):685-687.
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||
<span class="bold">PMID: </span><a href="/pubmed/28904032" target="_blank">28904032</a><a href="/pmc/articles/PMC5597011" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26610421">Pneumococcal Disease in the Era of Pneumococcal Conjugate Vaccine.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yildirim I,
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||
Shea KM,
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||
Pelton SI</span><br />
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||
<span class="medgenPMjournal">Infect Dis Clin North Am</span>
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||
2015 Dec;29(4):679-97.
|
||
doi: 10.1016/j.idc.2015.07.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26610421" target="_blank">26610421</a><a href="/pmc/articles/PMC4662776" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23971270">An evidence-based approach to managing acute otitis media.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nesbit CE,
|
||
Powers MC</span><br />
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||
<span class="medgenPMjournal">Pediatr Emerg Med Pract</span>
|
||
2013 Apr;10(4):1-26; quiz 26-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23971270" target="_blank">23971270</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mastoiditis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (188)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/35175990">Management of Acute Complicated Mastoiditis: A Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kaufmann MR,
|
||
Shetty K,
|
||
Camilon PR,
|
||
Shetty A,
|
||
Levi JR,
|
||
Devaiah AK</span><br />
|
||
<span class="medgenPMjournal">Pediatr Infect Dis J</span>
|
||
2022 Apr 1;41(4):297-301.
|
||
doi: 10.1097/INF.0000000000003452.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35175990" target="_blank">35175990</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34196007">Protons versus photons for the treatment of chordoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">El Sayed I,
|
||
Trifiletti DM,
|
||
Lehrer EJ,
|
||
Showalter TN,
|
||
Dutta SW</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2021 Jul 1;7(7):CD013224.
|
||
doi: 10.1002/14651858.CD013224.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34196007" target="_blank">34196007</a><a href="/pmc/articles/PMC8245311" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33881577">Pneumolabyrinth: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Botti C,
|
||
Castellucci A,
|
||
Crocetta FM,
|
||
Fornaciari M,
|
||
Giordano D,
|
||
Bassi C,
|
||
Ghidini A</span><br />
|
||
<span class="medgenPMjournal">Eur Arch Otorhinolaryngol</span>
|
||
2021 Dec;278(12):4619-4632.
|
||
Epub 2021 Apr 21
|
||
doi: 10.1007/s00405-021-06827-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33881577" target="_blank">33881577</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28879826">Management of paediatric acute mastoiditis: systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Loh R,
|
||
Phua M,
|
||
Shaw CL</span><br />
|
||
<span class="medgenPMjournal">J Laryngol Otol</span>
|
||
2018 Feb;132(2):96-104.
|
||
Epub 2017 Sep 7
|
||
doi: 10.1017/S0022215117001840.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28879826" target="_blank">28879826</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23870746">Chronic suppurative otitis media.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morris P</span><br />
|
||
<span class="medgenPMjournal">BMJ Clin Evid</span>
|
||
2012 Aug 6;2012
|
||
<span class="bold">PMID: </span><a href="/pubmed/23870746" target="_blank">23870746</a><a href="/pmc/articles/PMC3412293" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mastoiditis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (28)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
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|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
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|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Mastoiditis" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
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</div>
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|
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<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22mastoiditis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Mastoiditis%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Mastoiditis" target="_blank">MedlinePlus</a></li></ul></div>
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<a href="/pubmed/clinical?term=Mastoiditis" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Mastoiditis%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<div class="brieflinkpop offscreen_noflow">Related Medical Subject Headings</div>
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<p><a href="https://www.nlm.nih.gov/web_policies.html" class="text-white">Web Policies</a><br />
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