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<!--
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UID=488933
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ConceptID=C0745109
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Macular hyperpigmentation</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>488933</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0745109</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding; Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0011509">HP:0011509</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">Increased amount of pigmentation in the macula lutea. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Macular hyperpigmentation</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/868526" ref="tree=MeSH" title="MedGen record for Abnormal eye morphology">Abnormal eye morphology</a></span><ul><li><span class="TLline"><a href="/medgen/870893" ref="tree=MeSH" title="MedGen record for Abnormal posterior eye segment morphology">Abnormal posterior eye segment morphology</a></span><ul><li><span class="TLline"><a href="/medgen/871316" ref="tree=MeSH" title="MedGen record for Abnormal fundus morphology">Abnormal fundus morphology</a></span><ul><li><span class="TLline"><a href="/medgen/472885" ref="tree=MeSH" title="MedGen record for Abnormal retinal morphology">Abnormal retinal morphology</a></span><ul><li><span class="TLline"><a href="/medgen/1624166" ref="tree=MeSH" title="MedGen record for Abnormal macular morphology">Abnormal macular morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892991" ref="tree=MeSH" title="MedGen record for Abnormality of macular pigmentation">Abnormality of macular pigmentation</a></span><ul><li><span class="matched_ds">Macular hyperpigmentation</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_316921"><div><strong>Congenital hypotrichosis with juvenile macular dystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>316921</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1832162</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Congenital hypotrichosis with juvenile macular dystrophy (HJMD) is an autosomal recessive disorder characterized by hair loss followed by progressive macular degeneration and early blindness. Scalp hair is lost during the first months of life, with onset of retinal degeneration and vision loss a few years to 2 decades later (summary by Sprecher et al., 2001 and Indelman et al., 2002).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/316921">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_339002"><div><strong>Renal coloboma syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>339002</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1852759</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">PAX2-related disorder is an autosomal dominant disorder associated with renal and eye abnormalities. The disorder was originally referred to as renal coloboma syndrome and characterized by renal hypodysplasia and abnormalities of the optic nerve; with improved access to molecular testing, a wider range of phenotypes has been recognized in association with pathogenic variants in PAX2. Abnormal renal structure or function is noted in 92% of affected individuals and ophthalmologic abnormalities in 77% of affected individuals. Renal abnormalities can be clinically silent in rare individuals. In most individuals, clinically significant renal insufficiency / renal failure is reported. End-stage renal disease requiring renal transplant is not uncommon. Uric acid nephrolithiasis has been reported. Ophthalmologic abnormalities are typically described as optic nerve coloboma or dysplasia. Iris colobomas have not been reported in any individual with PAX2–related disorder. Ophthalmologic abnormalities may significantly impair vision in some individuals, while others have subtle changes only noted after detailed ophthalmologic examination. Additional clinical findings include high-frequency sensorineural hearing loss, soft skin, and ligamentous laxity. PAX2 pathogenic variants have been identified in multiple sporadic and familial cases of nonsyndromic renal disease including renal hypodysplasia and focal segmental glomerulosclerosis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/339002">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_483485"><div><strong>Cone-rod dystrophy 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>483485</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3489532</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cone-rod dystrophy (CORD) characteristically leads to early impairment of vision. An initial loss of color vision and of visual acuity is followed by nyctalopia (night blindness) and loss of peripheral visual fields. In extreme cases, these progressive symptoms are accompanied by widespread, advancing retinal pigmentation and chorioretinal atrophy of the central and peripheral retina (Moore, 1992). In many families, perhaps a majority, central and peripheral chorioretinal atrophy is not found (Tzekov, 1998). Genetic Heterogeneity of Autosomal Cone-Rod Dystrophy There are several other autosomal forms of CORD for which the molecular basis is known. CORD3 (604116) is caused by mutation in the ABCA4 gene (601691) on chromosome 1p22. CORD5 (600977) is caused by mutation in the PITPNM3 gene (608921) on chromosome 17p13. CORD6 (601777) is caused by mutation in the GUCY2D gene (600179) on chromosome 17p13.1. CORD9 (612775) is caused by mutation in the ADAM9 gene (602713) on chromosome 8p11. CORD10 (610283) is caused by mutation in the SEMA4A gene (607292) on chromosome 1q22. CORD11 (610381) is caused by mutation in the RAXL1 gene (610362) on chromosome 19p13. CORD12 (612657) is caused by mutation in the PROM1 gene (604365) on chromosome 4p15. CORD13 (608194) is caused by mutation in the RPGRIP1 gene (605446) on chromosome 14q11. CORD14 (see 602093) is caused by mutation in the GUCA1A gene (600364) on chromosome 6p21. CORD15 (613660) is caused by mutation in the CDHR1 gene (609502) on chromosome 10q23. CORD16 (614500) is caused by mutation in the C8ORF37 gene (614477) on chromosome 8q22. CORD18 (615374) is caused by mutation in the RAB28 gene (612994) on chromosome 4p15. CORD19 (615860) is caused by mutation in the TTLL5 gene (612268) on chromosome 14q24. CORD20 (615973) is caused by mutation in the POC1B gene (614784) on chromosome 12q21. CORD21 (616502) is caused by mutation in the DRAM2 gene (613360) on chromosome 1p13. CORD22 (619531) is caused by mutation in the TLCD3B gene (615175) on chromosome 16p11. CORD23 (see 613428) is caused by mutation in the C2ORF71 gene (PCARE; 613425) on chromosome 2p23. CORD24 (620342) is caused by mutation in the UNC119 gene (604011) on chromosome 17q11. A diagnosis of CORD was made in an individual with a mutation in the AIPL1 gene (604392.0004) on chromosome 17p13.1, as well as in an individual with a mutation in the UNC119 gene (604011.0001) on chromosome 17q11.2. Other mapped loci for autosomal CORD include CORD1 (600624) on chromosome 18q21.1-q21.3; CORD7 (603649) on chromosome 6q14; CORD8 (605549) on chromosome 1q12-q24; and CORD17 (615163) on chromosome 10q26. For a discussion of X-linked forms of cone-rod dystrophy, see CORDX1 (304020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/483485">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_483485" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cone-rod dystrophy 2</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_316921" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Congenital hypotrichosis with juvenile macular dystrophy</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_339002" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Renal coloboma syndrome</a></div></div>
|
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|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36924935">Treatment recommendations for acne-associated hyperpigmentation: Results of the Delphi consensus process and a literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Taylor S,
|
||
Elbuluk N,
|
||
Grimes P,
|
||
Chien A,
|
||
Hamzavi I,
|
||
Alexis A,
|
||
Gonzalez N,
|
||
Weiss J,
|
||
Kang S,
|
||
Desai SR</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2023 Aug;89(2):316-323.
|
||
Epub 2023 Mar 15
|
||
doi: 10.1016/j.jaad.2023.02.053.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36924935" target="_blank">36924935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33660856">Oral mycophenolate mofetil in the treatment of acquired dermal macular hyperpigmentation: An open-label pilot study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bishnoi A,
|
||
Vinay K,
|
||
Parsad D,
|
||
Kumar S,
|
||
Chatterjee D,
|
||
Nahar Saikia U,
|
||
Sendhil Kumaran M</span><br />
|
||
<span class="medgenPMjournal">Australas J Dermatol</span>
|
||
2021 Aug;62(3):278-285.
|
||
Epub 2021 Mar 4
|
||
doi: 10.1111/ajd.13567.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33660856" target="_blank">33660856</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30176055">A global consensus statement on ashy dermatosis, erythema dyschromicum perstans, lichen planus pigmentosus, idiopathic eruptive macular pigmentation, and Riehl's melanosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kumarasinghe SPW,
|
||
Pandya A,
|
||
Chandran V,
|
||
Rodrigues M,
|
||
Dlova NC,
|
||
Kang HY,
|
||
Ramam M,
|
||
Dayrit JF,
|
||
Goh BK,
|
||
Parsad D</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2019 Mar;58(3):263-272.
|
||
Epub 2018 Sep 3
|
||
doi: 10.1111/ijd.14189.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30176055" target="_blank">30176055</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22macular%20hyperpigmentation%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (4)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38994566">Quality of life in patients with acquired dermal macular hyperpigmentation: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jiang M,
|
||
Wang E,
|
||
Rodrigues M</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Dermatol</span>
|
||
2024 Nov 22;49(12):1504-1509.
|
||
doi: 10.1093/ced/llae224.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38994566" target="_blank">38994566</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38456556">Efficacy and safety of the combination of oral tranexamic acid and intense pulsed light versus oral tranexamic acid alone in the treatment of refractory Riehl's melanosis: A prospective, comparative study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xu Z,
|
||
Wang C,
|
||
Xing X,
|
||
Zhang C,
|
||
Xiang LF</span><br />
|
||
<span class="medgenPMjournal">J Cosmet Dermatol</span>
|
||
2024 Jun;23(6):2049-2057.
|
||
Epub 2024 Mar 8
|
||
doi: 10.1111/jocd.16257.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38456556" target="_blank">38456556</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36924935">Treatment recommendations for acne-associated hyperpigmentation: Results of the Delphi consensus process and a literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Taylor S,
|
||
Elbuluk N,
|
||
Grimes P,
|
||
Chien A,
|
||
Hamzavi I,
|
||
Alexis A,
|
||
Gonzalez N,
|
||
Weiss J,
|
||
Kang S,
|
||
Desai SR</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2023 Aug;89(2):316-323.
|
||
Epub 2023 Mar 15
|
||
doi: 10.1016/j.jaad.2023.02.053.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36924935" target="_blank">36924935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28971471">Dermatoscopic evaluation and histopathological correlation of acquired dermal macular hyperpigmentation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vinay K,
|
||
Bishnoi A,
|
||
Parsad D,
|
||
Saikia UN,
|
||
Sendhil Kumaran M</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2017 Dec;56(12):1395-1399.
|
||
Epub 2017 Oct 3
|
||
doi: 10.1111/ijd.13782.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28971471" target="_blank">28971471</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2715403">Penile melanosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Revuz J,
|
||
Clerici T</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
1989 Apr;20(4):567-70.
|
||
doi: 10.1016/s0190-9622(89)70064-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2715403" target="_blank">2715403</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Macular%20hyperpigmentation%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (19)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36449308">Vulvar Melanoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pye IM,
|
||
Saw RPM,
|
||
Saunderson RB</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2023 Jan 1;159(1):96.
|
||
doi: 10.1001/jamadermatol.2022.4550.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36449308" target="_blank">36449308</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35151757">Disorders of hyperpigmentation. Part I. Pathogenesis and clinical features of common pigmentary disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang RF,
|
||
Ko D,
|
||
Friedman BJ,
|
||
Lim HW,
|
||
Mohammad TF</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2023 Feb;88(2):271-288.
|
||
Epub 2022 Feb 11
|
||
doi: 10.1016/j.jaad.2022.01.051.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35151757" target="_blank">35151757</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31220891">Ashy dermatosis: a review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nguyen K,
|
||
Khachemoune A</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2019 May 15;25(5)
|
||
<span class="bold">PMID: </span><a href="/pubmed/31220891" target="_blank">31220891</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30027914">Optimizing Q-switched lasers for melasma and acquired dermal melanoses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aurangabadkar SJ</span><br />
|
||
<span class="medgenPMjournal">Indian J Dermatol Venereol Leprol</span>
|
||
2019 Jan-Feb;85(1):10-17.
|
||
doi: 10.4103/ijdvl.IJDVL_1086_16.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30027914" target="_blank">30027914</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23774424">Incontinentia pigmenti.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">B S G,
|
||
Pai GS,
|
||
Pai AH,
|
||
Vinekar AS,
|
||
Pai HS,
|
||
Noronha T,
|
||
Fernandes MS</span><br />
|
||
<span class="medgenPMjournal">Kathmandu Univ Med J (KUMJ)</span>
|
||
2013 Jan-Mar;11(41):91-3.
|
||
doi: 10.3126/kumj.v11i1.11052.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23774424" target="_blank">23774424</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Macular%20hyperpigmentation%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (40)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37767951">Acquired dermal macular hyperpigmentation: an overview of the recent updates.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah S,
|
||
Baskaran N,
|
||
Vinay K,
|
||
Bishnoi A,
|
||
Parsad D,
|
||
Kumaran MS</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2023 Dec;62(12):1447-1457.
|
||
Epub 2023 Sep 28
|
||
doi: 10.1111/ijd.16859.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37767951" target="_blank">37767951</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36924935">Treatment recommendations for acne-associated hyperpigmentation: Results of the Delphi consensus process and a literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Taylor S,
|
||
Elbuluk N,
|
||
Grimes P,
|
||
Chien A,
|
||
Hamzavi I,
|
||
Alexis A,
|
||
Gonzalez N,
|
||
Weiss J,
|
||
Kang S,
|
||
Desai SR</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2023 Aug;89(2):316-323.
|
||
Epub 2023 Mar 15
|
||
doi: 10.1016/j.jaad.2023.02.053.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36924935" target="_blank">36924935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31220891">Ashy dermatosis: a review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nguyen K,
|
||
Khachemoune A</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2019 May 15;25(5)
|
||
<span class="bold">PMID: </span><a href="/pubmed/31220891" target="_blank">31220891</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30027914">Optimizing Q-switched lasers for melasma and acquired dermal melanoses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aurangabadkar SJ</span><br />
|
||
<span class="medgenPMjournal">Indian J Dermatol Venereol Leprol</span>
|
||
2019 Jan-Feb;85(1):10-17.
|
||
doi: 10.4103/ijdvl.IJDVL_1086_16.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30027914" target="_blank">30027914</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10599387">Melasma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kauh YC,
|
||
Zachian TF</span><br />
|
||
<span class="medgenPMjournal">Adv Exp Med Biol</span>
|
||
1999;455:491-9.
|
||
doi: 10.1007/978-1-4615-4857-7_72.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10599387" target="_blank">10599387</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Macular%20hyperpigmentation%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37767951">Acquired dermal macular hyperpigmentation: an overview of the recent updates.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah S,
|
||
Baskaran N,
|
||
Vinay K,
|
||
Bishnoi A,
|
||
Parsad D,
|
||
Kumaran MS</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2023 Dec;62(12):1447-1457.
|
||
Epub 2023 Sep 28
|
||
doi: 10.1111/ijd.16859.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37767951" target="_blank">37767951</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32932271">Treatment of Refractory Melasma in Asians With the Picosecond Alexandrite Laser.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Polnikorn N,
|
||
Tanghetti E</span><br />
|
||
<span class="medgenPMjournal">Dermatol Surg</span>
|
||
2020 Dec;46(12):1651-1656.
|
||
doi: 10.1097/DSS.0000000000002612.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32932271" target="_blank">32932271</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24732760">Juvenile-onset macular degeneration and allied disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">North V,
|
||
Gelman R,
|
||
Tsang SH</span><br />
|
||
<span class="medgenPMjournal">Dev Ophthalmol</span>
|
||
2014;53:44-52.
|
||
Epub 2014 Apr 10
|
||
doi: 10.1159/000357293.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24732760" target="_blank">24732760</a><a href="/pmc/articles/PMC4405533" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18416855">Brown-Vialetto-Van Laere syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sathasivam S</span><br />
|
||
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
|
||
2008 Apr 17;3:9.
|
||
doi: 10.1186/1750-1172-3-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18416855" target="_blank">18416855</a><a href="/pmc/articles/PMC2346457" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2715403">Penile melanosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Revuz J,
|
||
Clerici T</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
1989 Apr;20(4):567-70.
|
||
doi: 10.1016/s0190-9622(89)70064-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2715403" target="_blank">2715403</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Macular%20hyperpigmentation%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37767951">Acquired dermal macular hyperpigmentation: an overview of the recent updates.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah S,
|
||
Baskaran N,
|
||
Vinay K,
|
||
Bishnoi A,
|
||
Parsad D,
|
||
Kumaran MS</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2023 Dec;62(12):1447-1457.
|
||
Epub 2023 Sep 28
|
||
doi: 10.1111/ijd.16859.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37767951" target="_blank">37767951</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31566833">Psychological disturbances in patients with pigmentary disorders: a cross-sectional study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dabas G,
|
||
Vinay K,
|
||
Parsad D,
|
||
Kumar A,
|
||
Kumaran MS</span><br />
|
||
<span class="medgenPMjournal">J Eur Acad Dermatol Venereol</span>
|
||
2020 Feb;34(2):392-399.
|
||
Epub 2019 Oct 31
|
||
doi: 10.1111/jdv.15987.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31566833" target="_blank">31566833</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29544741">Clinical, dermoscopic, and trichoscopic analysis of frontal fibrosing alopecia associated with acquired dermal macular hyperpigmentation: A cross sectional observational case-control study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kumaran MS,
|
||
Razmi T M,
|
||
Vinay K,
|
||
Parsad D</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2018 Sep;79(3):588-591.
|
||
Epub 2018 Mar 12
|
||
doi: 10.1016/j.jaad.2018.03.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29544741" target="_blank">29544741</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28971471">Dermatoscopic evaluation and histopathological correlation of acquired dermal macular hyperpigmentation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vinay K,
|
||
Bishnoi A,
|
||
Parsad D,
|
||
Saikia UN,
|
||
Sendhil Kumaran M</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2017 Dec;56(12):1395-1399.
|
||
Epub 2017 Oct 3
|
||
doi: 10.1111/ijd.13782.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28971471" target="_blank">28971471</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2715403">Penile melanosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Revuz J,
|
||
Clerici T</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
1989 Apr;20(4):567-70.
|
||
doi: 10.1016/s0190-9622(89)70064-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2715403" target="_blank">2715403</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Macular%20hyperpigmentation%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (18)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/38994566">Quality of life in patients with acquired dermal macular hyperpigmentation: a systematic review.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Jiang M,
|
||
Wang E,
|
||
Rodrigues M</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Dermatol</span>
|
||
2024 Nov 22;49(12):1504-1509.
|
||
doi: 10.1093/ced/llae224.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38994566" target="_blank">38994566</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Macular%20hyperpigmentation%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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