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<!--
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UID=409660
|
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ConceptID=C1968729
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Increased muscle glycogen content</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>409660</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1968729</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Glycogen content in skeletal muscle, increased</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0009051">HP:0009051</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">An increased amount of glycogen in muscle tissue. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1968729[DISCUI]&test_type=Clinical" ref="ncbi_uid=409660">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=409660" ref="ncbi_uid=409660">V</a></span></span><span class="TLline">Increased muscle glycogen content</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1704511" ref="tree=MeSH" title="MedGen record for Abnormal tissue metabolite concentration">Abnormal tissue metabolite concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1815100" ref="tree=MeSH" title="MedGen record for Abnormal muscle tissue metabolite concentration">Abnormal muscle tissue metabolite concentration</a></span><ul><li><span class="TLline"><a href="/medgen/868581" ref="tree=MeSH" title="MedGen record for Abnormal muscle glycogen content">Abnormal muscle glycogen content</a></span><ul><li><span class="matched_ds">Increased muscle glycogen content</span><ul><li><span class="TLline"><a href="/medgen/868175" ref="tree=MeSH" title="MedGen record for Glycogen accumulation in muscle fiber lysosomes">Glycogen accumulation in muscle fiber lysosomes</a></span></li><li><span class="TLline"><a href="/medgen/868174" ref="tree=MeSH" title="MedGen record for Increased sarcoplasmic glycogen">Increased sarcoplasmic glycogen</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_5340"><div><strong>Glycogen storage disease, type II</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5340</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017921</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pompe disease is classified by age of onset, organ involvement, severity, and rate of progression. Infantile-onset Pompe disease (IOPD; individuals with onset before age 12 months with cardiomyopathy) may be apparent in utero but more typically onset is at the median age of four months with hypotonia, generalized muscle weakness, feeding difficulties, failure to thrive, respiratory distress, and hypertrophic cardiomyopathy. Without treatment by enzyme replacement therapy (ERT), IOPD commonly results in death by age two years from progressive left ventricular outflow obstruction and respiratory insufficiency. Late-onset Pompe disease (LOPD; including: (a) individuals with onset before age 12 months without cardiomyopathy; and (b) all individuals with onset after age 12 months) is characterized by proximal muscle weakness and respiratory insufficiency; clinically significant cardiac involvement is uncommon.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5340">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_5342"><div><strong>Glycogen storage disease, type VII</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5342</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017926</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Glycogen storage disease VII is an autosomal recessive metabolic disorder characterized clinically by exercise intolerance, muscle cramping, exertional myopathy, and compensated hemolysis. Myoglobinuria may also occur. The deficiency of the muscle isoform of PFK results in a total and partial loss of muscle and red cell PFK activity, respectively. Raben and Sherman (1995) noted that not all patients with GSD VII seek medical care because in some cases it is a relatively mild disorder.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5342">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_107772"><div><strong>Glycogen storage disease IXb</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>107772</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0543514</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Phosphorylase kinase (PhK) deficiency causing glycogen storage disease type IX (GSD IX) results from deficiency of the enzyme phosphorylase b kinase, which has a major regulatory role in the breakdown of glycogen. The two types of PhK deficiency are liver PhK deficiency (characterized by early childhood onset of hepatomegaly and growth restriction, and often, but not always, fasting ketosis and hypoglycemia) and muscle PhK deficiency, which is considerably rarer (characterized by any of the following: exercise intolerance, myalgia, muscle cramps, myoglobinuria, and progressive muscle weakness). While symptoms and biochemical abnormalities of liver PhK deficiency were thought to improve with age, it is becoming evident that affected individuals need to be monitored for long-term complications such as liver fibrosis and cirrhosis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/107772">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_335112"><div><strong>Glycogen storage disease IXd</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>335112</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1845151</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Phosphorylase kinase (PhK) deficiency causing glycogen storage disease type IX (GSD IX) results from deficiency of the enzyme phosphorylase b kinase, which has a major regulatory role in the breakdown of glycogen. The two types of PhK deficiency are liver PhK deficiency (characterized by early childhood onset of hepatomegaly and growth restriction, and often, but not always, fasting ketosis and hypoglycemia) and muscle PhK deficiency, which is considerably rarer (characterized by any of the following: exercise intolerance, myalgia, muscle cramps, myoglobinuria, and progressive muscle weakness). While symptoms and biochemical abnormalities of liver PhK deficiency were thought to improve with age, it is becoming evident that affected individuals need to be monitored for long-term complications such as liver fibrosis and cirrhosis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/335112">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_442873"><div><strong>Glycogen storage disease due to muscle beta-enolase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>442873</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2752027</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Muscle beta-enolase deficiency is a glycolysis disorder reported in one patient to date and characterized clinically by exercise intolerance and myalgia due to severe enolase deficiency in muscle.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/442873">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_463248"><div><strong>Mitochondrial myopathy with reversible cytochrome C oxidase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>463248</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151898</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Infantile mitochondrial myopathy due to reversible COX deficiency is a rare mitochondrial disorder characterized by onset in infancy of severe hypotonia and generalized muscle weakness associated with lactic acidosis, but is distinguished from other mitochondrial disorders in that affected individuals recover spontaneously after 1 year of age (summary by Mimaki et al., 2010). See also transient infantile liver failure (LFIT; 613070), which is a similar disorder.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/463248">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_442873" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease due to muscle beta-enolase deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_107772" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease IXb</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_335112" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease IXd</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5340" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease, type II</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5342" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease, type VII</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_463248" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mitochondrial myopathy with reversible cytochrome C oxidase deficiency</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31917327">Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bragato C,
|
||
Carra S,
|
||
Blasevich F,
|
||
Salerno F,
|
||
Brix A,
|
||
Bassi A,
|
||
Beltrame M,
|
||
Cotelli F,
|
||
Maggi L,
|
||
Mantegazza R,
|
||
Mora M</span><br />
|
||
<span class="medgenPMjournal">Biochim Biophys Acta Mol Basis Dis</span>
|
||
2020 May 1;1866(5):165662.
|
||
Epub 2020 Jan 7
|
||
doi: 10.1016/j.bbadis.2020.165662.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31917327" target="_blank">31917327</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26667687">ENDURANCE TRAINING IN FASTING CONDITIONS: BIOLOGICAL ADAPTATIONS AND BODY WEIGHT MANAGEMENT.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vicente-Salar N,
|
||
Urdampilleta Otegui A,
|
||
Roche Collado E</span><br />
|
||
<span class="medgenPMjournal">Nutr Hosp</span>
|
||
2015 Dec 1;32(6):2409-20.
|
||
doi: 10.3305/nh.2015.32.6.9488.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26667687" target="_blank">26667687</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23151136">Regulation of skeletal muscle plasticity by glycogen synthase kinase-3β: a potential target for the treatment of muscle wasting.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Verhees KJ,
|
||
Pansters NA,
|
||
Schols AM,
|
||
Langen RC</span><br />
|
||
<span class="medgenPMjournal">Curr Pharm Des</span>
|
||
2013;19(18):3276-98.
|
||
doi: 10.2174/1381612811319180011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23151136" target="_blank">23151136</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(increased%20muscle%20glycogen%20content)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (8)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/27193231">Creatine ingestion augments dietary carbohydrate mediated muscle glycogen supercompensation during the initial 24 h of recovery following prolonged exhaustive exercise in humans.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roberts PA,
|
||
Fox J,
|
||
Peirce N,
|
||
Jones SW,
|
||
Casey A,
|
||
Greenhaff PL</span><br />
|
||
<span class="medgenPMjournal">Amino Acids</span>
|
||
2016 Aug;48(8):1831-42.
|
||
Epub 2016 May 19
|
||
doi: 10.1007/s00726-016-2252-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27193231" target="_blank">27193231</a><a href="/pmc/articles/PMC4974290" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16567381">Effects of an ad libitum, high carbohydrate diet and aerobic exercise training on insulin action and muscle metabolism in older men and women.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hays NP,
|
||
Starling RD,
|
||
Sullivan DH,
|
||
Fluckey JD,
|
||
Coker RH,
|
||
Williams RH,
|
||
Evans WJ</span><br />
|
||
<span class="medgenPMjournal">J Gerontol A Biol Sci Med Sci</span>
|
||
2006 Mar;61(3):299-304.
|
||
doi: 10.1093/gerona/61.3.299.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16567381" target="_blank">16567381</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16469933">Effect of short-term sprint interval training on human skeletal muscle carbohydrate metabolism during exercise and time-trial performance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Burgomaster KA,
|
||
Heigenhauser GJ,
|
||
Gibala MJ</span><br />
|
||
<span class="medgenPMjournal">J Appl Physiol (1985)</span>
|
||
2006 Jun;100(6):2041-7.
|
||
Epub 2006 Feb 9
|
||
doi: 10.1152/japplphysiol.01220.2005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16469933" target="_blank">16469933</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20muscle%20glycogen%20content%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/27193231">Creatine ingestion augments dietary carbohydrate mediated muscle glycogen supercompensation during the initial 24 h of recovery following prolonged exhaustive exercise in humans.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roberts PA,
|
||
Fox J,
|
||
Peirce N,
|
||
Jones SW,
|
||
Casey A,
|
||
Greenhaff PL</span><br />
|
||
<span class="medgenPMjournal">Amino Acids</span>
|
||
2016 Aug;48(8):1831-42.
|
||
Epub 2016 May 19
|
||
doi: 10.1007/s00726-016-2252-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27193231" target="_blank">27193231</a><a href="/pmc/articles/PMC4974290" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16567381">Effects of an ad libitum, high carbohydrate diet and aerobic exercise training on insulin action and muscle metabolism in older men and women.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hays NP,
|
||
Starling RD,
|
||
Sullivan DH,
|
||
Fluckey JD,
|
||
Coker RH,
|
||
Williams RH,
|
||
Evans WJ</span><br />
|
||
<span class="medgenPMjournal">J Gerontol A Biol Sci Med Sci</span>
|
||
2006 Mar;61(3):299-304.
|
||
doi: 10.1093/gerona/61.3.299.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16567381" target="_blank">16567381</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7498245">Determinants of insulin-stimulated skeletal muscle glycogen metabolism in man.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schalin-Jäntti C,
|
||
Laurila E,
|
||
Löfman M,
|
||
Groop LC</span><br />
|
||
<span class="medgenPMjournal">Eur J Clin Invest</span>
|
||
1995 Sep;25(9):693-8.
|
||
doi: 10.1111/j.1365-2362.1995.tb01988.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7498245" target="_blank">7498245</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20muscle%20glycogen%20content%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/27193231">Creatine ingestion augments dietary carbohydrate mediated muscle glycogen supercompensation during the initial 24 h of recovery following prolonged exhaustive exercise in humans.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roberts PA,
|
||
Fox J,
|
||
Peirce N,
|
||
Jones SW,
|
||
Casey A,
|
||
Greenhaff PL</span><br />
|
||
<span class="medgenPMjournal">Amino Acids</span>
|
||
2016 Aug;48(8):1831-42.
|
||
Epub 2016 May 19
|
||
doi: 10.1007/s00726-016-2252-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27193231" target="_blank">27193231</a><a href="/pmc/articles/PMC4974290" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25385360">Oral conjugated linoleic acid supplementation enhanced glycogen resynthesis in exercised human skeletal muscle.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tsao JP,
|
||
Liao SF,
|
||
Korivi M,
|
||
Hou CW,
|
||
Kuo CH,
|
||
Wang HF,
|
||
Cheng IS</span><br />
|
||
<span class="medgenPMjournal">J Sports Sci</span>
|
||
2015;33(9):915-23.
|
||
Epub 2014 Nov 11
|
||
doi: 10.1080/02640414.2014.970219.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25385360" target="_blank">25385360</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16567381">Effects of an ad libitum, high carbohydrate diet and aerobic exercise training on insulin action and muscle metabolism in older men and women.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hays NP,
|
||
Starling RD,
|
||
Sullivan DH,
|
||
Fluckey JD,
|
||
Coker RH,
|
||
Williams RH,
|
||
Evans WJ</span><br />
|
||
<span class="medgenPMjournal">J Gerontol A Biol Sci Med Sci</span>
|
||
2006 Mar;61(3):299-304.
|
||
doi: 10.1093/gerona/61.3.299.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16567381" target="_blank">16567381</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16051629">Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McConell GK,
|
||
Lee-Young RS,
|
||
Chen ZP,
|
||
Stepto NK,
|
||
Huynh NN,
|
||
Stephens TJ,
|
||
Canny BJ,
|
||
Kemp BE</span><br />
|
||
<span class="medgenPMjournal">J Physiol</span>
|
||
2005 Oct 15;568(Pt 2):665-76.
|
||
Epub 2005 Jul 28
|
||
doi: 10.1113/jphysiol.2005.089839.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16051629" target="_blank">16051629</a><a href="/pmc/articles/PMC1474728" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10846030">Dietary carbohydrate, muscle glycogen content, and endurance performance in well-trained women.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Walker JL,
|
||
Heigenhauser GJ,
|
||
Hultman E,
|
||
Spriet LL</span><br />
|
||
<span class="medgenPMjournal">J Appl Physiol (1985)</span>
|
||
2000 Jun;88(6):2151-8.
|
||
doi: 10.1152/jappl.2000.88.6.2151.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10846030" target="_blank">10846030</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20muscle%20glycogen%20content%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/27193231">Creatine ingestion augments dietary carbohydrate mediated muscle glycogen supercompensation during the initial 24 h of recovery following prolonged exhaustive exercise in humans.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Roberts PA,
|
||
Fox J,
|
||
Peirce N,
|
||
Jones SW,
|
||
Casey A,
|
||
Greenhaff PL</span><br />
|
||
<span class="medgenPMjournal">Amino Acids</span>
|
||
2016 Aug;48(8):1831-42.
|
||
Epub 2016 May 19
|
||
doi: 10.1007/s00726-016-2252-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27193231" target="_blank">27193231</a><a href="/pmc/articles/PMC4974290" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20muscle%20glycogen%20content%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/16051629">Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McConell GK,
|
||
Lee-Young RS,
|
||
Chen ZP,
|
||
Stepto NK,
|
||
Huynh NN,
|
||
Stephens TJ,
|
||
Canny BJ,
|
||
Kemp BE</span><br />
|
||
<span class="medgenPMjournal">J Physiol</span>
|
||
2005 Oct 15;568(Pt 2):665-76.
|
||
Epub 2005 Jul 28
|
||
doi: 10.1113/jphysiol.2005.089839.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16051629" target="_blank">16051629</a><a href="/pmc/articles/PMC1474728" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10846030">Dietary carbohydrate, muscle glycogen content, and endurance performance in well-trained women.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Walker JL,
|
||
Heigenhauser GJ,
|
||
Hultman E,
|
||
Spriet LL</span><br />
|
||
<span class="medgenPMjournal">J Appl Physiol (1985)</span>
|
||
2000 Jun;88(6):2151-8.
|
||
doi: 10.1152/jappl.2000.88.6.2151.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10846030" target="_blank">10846030</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20muscle%20glycogen%20content%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1968729%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (3)</a></li>
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<li><a href="/gtr/tests?term=C1968729%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
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