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<!--
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||
UID=375403
|
||
ConceptID=C1844374
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Persistent bleeding after trauma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>375403</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1844374</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Excessive bleeding after minor trauma; Frequent bleeding with trauma; Prolonged bleeding after minor trauma</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0001934">HP:0001934</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1844374[DISCUI]&test_type=Clinical" ref="ncbi_uid=375403">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Persistent bleeding after trauma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/163092" ref="tree=MeSH" title="MedGen record for Abnormality of blood and blood-forming tissues">Abnormality of blood and blood-forming tissues</a></span><ul><li><span class="TLline"><a href="/medgen/264316" ref="tree=MeSH" title="MedGen record for Abnormal bleeding">Abnormal bleeding</a></span><ul><li><span class="matched_ds">Persistent bleeding after trauma</span></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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<div class="portlet mgSection" id="ID_112">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_945"><div><strong>Hereditary factor IX deficiency disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>945</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0008533</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hemophilia B is characterized by deficiency in factor IX clotting activity that results in prolonged oozing after injuries, tooth extractions, or surgery, and delayed or recurrent bleeding prior to complete wound healing. The age of diagnosis and frequency of bleeding episodes are related to the level of factor IX clotting activity. In any individual with hemophilia B, bleeding episodes may be more frequent in childhood and adolescence than in adulthood. Individuals with severe hemophilia B are usually diagnosed during the first two years of life. Without prophylactic treatment, they may average up to two to five spontaneous bleeding episodes each month, including spontaneous joint or muscle bleeds, and prolonged bleeding or excessive pain and swelling from minor injuries, surgery, and tooth extractions. Individuals with moderate hemophilia B seldom have spontaneous bleeding, although it varies between individuals; however, they do have prolonged or delayed oozing after relatively minor trauma and are usually diagnosed before age five to six years. The frequency of bleeding episodes varies from once a month to once a year. Individuals with mild hemophilia B do not have spontaneous bleeding episodes; however, without pre- and postoperative treatment, abnormal bleeding occurs with surgery or tooth extractions. The frequency of bleeding may vary from once a year to once every ten years. Individuals with mild hemophilia B are often not diagnosed until later in life. Approximately 30% of heterozygous females have factor IX clotting activity lower than 40% and are at risk for bleeding (even if the affected family member has mild hemophilia B). As in males, bleeding severity generally correlates with factor levels. After major trauma or invasive procedures, prolonged or excessive bleeding usually occurs, regardless of severity.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/945">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_5501"><div><strong>Hereditary factor VIII deficiency disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5501</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0019069</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hemophilia A is characterized by deficiency in factor VIII clotting activity that results in prolonged bleeding after injuries, tooth extractions, or surgery, and delayed or recurrent bleeding prior to complete wound healing. The age of diagnosis and frequency of bleeding episodes are related to the level of factor VIII clotting activity. Individuals with severe hemophilia A are usually diagnosed during the first two years of life following oral or soft tissue bleeding either with procedures or due to a known family history of hemophilia. Without prophylactic treatment, individuals may average up to two to five spontaneous bleeding episodes each month including spontaneous joint bleeds or deep-muscle hematomas, and prolonged bleeding or excessive pain and swelling from minor injuries, surgery, and tooth extractions. Individuals with moderate hemophilia A seldom have spontaneous bleeding, although it varies between individuals; however, they do have prolonged or delayed bleeding after relatively minor trauma and are usually diagnosed before age five to six years; the frequency of bleeding episodes varies, usually from once a month to once a year. Individuals with mild hemophilia A do not have spontaneous bleeding episodes; however, without pre- and postoperative treatment, abnormal bleeding occurs with surgery or tooth extractions; the frequency of bleeding episodes varies widely, typically from once a year to once every ten years. Individuals with mild hemophilia A are often not diagnosed until later in life. Approximately 30% of heterozygous females have factor VIII clotting activity below 40% and are at risk for bleeding (even if males in the family are only mildly affected). After major trauma or invasive procedures, prolonged or excessive bleeding usually occurs, regardless of severity. In addition, 25% of heterozygous females with normal factor VIII clotting activity report an increased bleeding tendency.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5501">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_220393"><div><strong>von Willebrand disease type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>220393</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1264039</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Von Willebrand disease (VWD) is characterized by mucocutaneous bleeding and excessive bleeding with trauma and procedures. Individuals with more severe forms of VWD are also at-risk for musculoskeletal bleeding. Mucocutaneous bleeding can include easy bruising, prolonged bleeding from minor wounds, epistaxis, oral cavity bleeding, heavy menstrual bleeding, gastrointestinal bleeding, and bleeding with hemostatic challenges such as dental work, childbirth, and surgery. Bleeding severity can vary widely in VWD, even between affected individuals within the same family. For some with VWD the bleeding phenotype may only become apparent upon hemostatic challenge, while others may have frequent spontaneous bleeding.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/220393">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_266075"><div><strong>von Willebrand disease type 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>266075</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1264041</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Von Willebrand disease (VWD) is characterized by mucocutaneous bleeding and excessive bleeding with trauma and procedures. Individuals with more severe forms of VWD are also at-risk for musculoskeletal bleeding. Mucocutaneous bleeding can include easy bruising, prolonged bleeding from minor wounds, epistaxis, oral cavity bleeding, heavy menstrual bleeding, gastrointestinal bleeding, and bleeding with hemostatic challenges such as dental work, childbirth, and surgery. Bleeding severity can vary widely in VWD, even between affected individuals within the same family. For some with VWD the bleeding phenotype may only become apparent upon hemostatic challenge, while others may have frequent spontaneous bleeding.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/266075">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_344008"><div><strong>Platelet-type bleeding disorder 8</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>344008</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1853278</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Platelet-type bleeding disorder-8 (BDPLT8) is an autosomal recessive condition characterized by mild to moderate mucocutaneous bleeding and excessive bleeding after surgery or trauma. The defect is due to the inability of ADP to induce platelet aggregation (review by Cattaneo, 2011).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/344008">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_749036"><div><strong>Congenital afibrinogenemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>749036</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2584774</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Inherited disorders of fibrinogen affect either the quantity (afibrinogenemia and hypofibrinogenemia; 202400) or the quality (dysfibrinogenemia; 616004) of the circulating fibrinogen or both (hypodysfibrinogenemia; see 616004). Afibrinogenemia is characterized by the complete absence of immunoreactive fibrinogen. Bleeding due to afibrinogenemia usually manifests in the neonatal period, with 85% of cases presenting umbilical cord bleeding, but a later age of onst is not unusual. Bleeding may occur in the skin, gastrointestinal tract, genitourinary tract, or the central nervous system, with intracranial hemorrhage being reported as the major cause of death. Patients are susceptible to spontaneous rupture of the spleen. Menstruating women may experience menometrorrhagia. First-trimester abortion is common. Both arterial and venous thromboembolic complications have been reported (summary by de Moerloose and Neerman-Arbez, 2009). Hypofibrinogenemia is characterized by reduced amounts of immunoreactive fibrinogen. Patients are often heterozygous carriers of afibrinogenemia mutations and are usually asymptomatic. However, they may bleed when exposed to trauma or if they have a second associated hemostatic abnormality. Women may experience miscarriages. Liver disease occurs in rare cases (summary by de Moerloose and Neerman-Arbez, 2009).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/749036">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_442497"><div><strong>Factor XIII, A subunit, deficiency of</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>442497</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2750514</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Factor XIII deficiency is an autosomal recessive hematologic disorder characterized by increased bleeding and poor wound healing. Most cases of congenital factor XIII deficiency result from mutation in the A subunit (Kangsadalampai et al., 1999). Ichinose et al. (1996, 2000) proposed a classification of factor XIII deficiency: XIIIA deficiency (formerly 'type II' F13 deficiency) and XIIIB deficiency (formerly 'type I' F13 deficiency), as well as a possible combined deficiency of the 2.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/442497">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_414178"><div><strong>Alpha-2-plasmin inhibitor deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>414178</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2752081</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Alpha-2-plasmin inhibitor deficiency is a rare autosomal recessive hemorrhagic diathesis. Most bleeds are severe, appear during childhood, and, in a few cases, umbilical bleeding is the first manifestation. Some homozygous patients present only moderate bleeding (Favier et al., 2001).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/414178">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462239"><div><strong>Factor 5 and Factor VIII, combined deficiency of, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462239</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3150889</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Combined deficiency of factor V and factor VIII type 2 (F5F8D2) is characterized by bleeding symptoms similar to those in hemophilia (306700) or parahemophilia (227400), caused by single deficiency of FV (612309) or FVIII (300841), respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma FV and FVIII antigen and activity levels are in the range of 5 to 30%. Inheritance of F5F8D2 is autosomal recessive and distinct from the coinheritance of FV deficiency and FVIII deficiency (summary by Zhang and Ginsburg, 2004). For a general phenotypic description and a discussion of genetic heterogeneity of F5F8D, see 227300.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462239">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_481386"><div><strong>Hermansky-Pudlak syndrome 7</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>481386</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3279756</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hermansky-Pudlak syndrome (HPS) is characterized by oculocutaneous albinism, a bleeding diathesis, and, in some individuals, pulmonary fibrosis, granulomatous colitis, and/or immunodeficiency. Ocular findings include nystagmus, reduced iris pigment, reduced retinal pigment, foveal hypoplasia with significant reduction in visual acuity (usually in the range of 20/50 to 20/400), and strabismus in many individuals. Hair color ranges from white to brown; skin color ranges from white to olive and is usually at least a shade lighter than that of other family members. The bleeding diathesis can result in variable degrees of bruising, epistaxis, gingival bleeding, postpartum hemorrhage, colonic bleeding, and prolonged bleeding with menses or after tooth extraction, circumcision, and/or other surgeries. Pulmonary fibrosis, colitis, and/or neutropenia have been reported in individuals with pathogenic variants in some HPS-related genes. Pulmonary fibrosis, a restrictive lung disease, typically causes symptoms in the early 30s and can progress to death within a decade. Granulomatous colitis is severe in about 15% of affected individuals. Neutropenia and/or immune defects occur primarily in individuals with pathogenic variants in AP3B1 and AP3D1.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/481386">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_763703"><div><strong>Thrombocytopenia, X-linked, with or without dyserythropoietic anemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>763703</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3550789</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">GATA1-related cytopenia is characterized by thrombocytopenia and/or anemia ranging from mild to severe. Thrombocytopenia typically presents in infancy as a bleeding disorder with easy bruising and mucosal bleeding (e.g., epistaxis). Anemia ranges from minimal (mild dyserythropoiesis) to severe (hydrops fetalis requiring in utero transfusion). At the extreme end of the clinical spectrum, severe hemorrhage and/or erythrocyte transfusion dependence are lifelong; at the milder end, anemia and the risk for bleeding may decrease spontaneously with age. One or more of the following may also be present: neutropenia, splenomegaly, cryptorchidism, hypospadias, and rarely additional clinical features of Diamond-Blackfan anemia. Heterozygous females may have mild-to-moderate symptoms such as menorrhagia. Rarely, GATA1-related cytopenia can progress to myelodysplastic syndrome or aplastic anemia.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/763703">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_414178" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Alpha-2-plasmin inhibitor deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_749036" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Congenital afibrinogenemia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462239" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Factor 5 and Factor VIII, combined deficiency of, 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_442497" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Factor XIII, A subunit, deficiency of</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_945" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary factor IX deficiency disease</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (11)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5501" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary factor VIII deficiency disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_481386" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hermansky-Pudlak syndrome 7</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_344008" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Platelet-type bleeding disorder 8</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_763703" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thrombocytopenia, X-linked, with or without dyserythropoietic anemia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_220393" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">von Willebrand disease type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_266075" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">von Willebrand disease type 3</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34863377">Surgical Treatment for Osteochondral Lesions of the Talus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Powers RT,
|
||
Dowd TC,
|
||
Giza E</span><br />
|
||
<span class="medgenPMjournal">Arthroscopy</span>
|
||
2021 Dec;37(12):3393-3396.
|
||
doi: 10.1016/j.arthro.2021.10.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34863377" target="_blank">34863377</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23243113">American Medical Society for Sports Medicine position statement: concussion in sport.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harmon KG,
|
||
Drezner JA,
|
||
Gammons M,
|
||
Guskiewicz KM,
|
||
Halstead M,
|
||
Herring SA,
|
||
Kutcher JS,
|
||
Pana A,
|
||
Putukian M,
|
||
Roberts WO</span><br />
|
||
<span class="medgenPMjournal">Br J Sports Med</span>
|
||
2013 Jan;47(1):15-26.
|
||
doi: 10.1136/bjsports-2012-091941.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23243113" target="_blank">23243113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20817498">Treatment of haemothorax.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boersma WG,
|
||
Stigt JA,
|
||
Smit HJ</span><br />
|
||
<span class="medgenPMjournal">Respir Med</span>
|
||
2010 Nov;104(11):1583-7.
|
||
doi: 10.1016/j.rmed.2010.08.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20817498" target="_blank">20817498</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(persistent%20bleeding%20after%20trauma)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (75)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33646273">Recovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kowalski RG,
|
||
Hammond FM,
|
||
Weintraub AH,
|
||
Nakase-Richardson R,
|
||
Zafonte RD,
|
||
Whyte J,
|
||
Giacino JT</span><br />
|
||
<span class="medgenPMjournal">JAMA Neurol</span>
|
||
2021 May 1;78(5):548-557.
|
||
doi: 10.1001/jamaneurol.2021.0084.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33646273" target="_blank">33646273</a><a href="/pmc/articles/PMC7922241" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30044935">Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sperry JL,
|
||
Guyette FX,
|
||
Brown JB,
|
||
Yazer MH,
|
||
Triulzi DJ,
|
||
Early-Young BJ,
|
||
Adams PW,
|
||
Daley BJ,
|
||
Miller RS,
|
||
Harbrecht BG,
|
||
Claridge JA,
|
||
Phelan HA,
|
||
Witham WR,
|
||
Putnam AT,
|
||
Duane TM,
|
||
Alarcon LH,
|
||
Callaway CW,
|
||
Zuckerbraun BS,
|
||
Neal MD,
|
||
Rosengart MR,
|
||
Forsythe RM,
|
||
Billiar TR,
|
||
Yealy DM,
|
||
Peitzman AB,
|
||
Zenati MS;
|
||
PAMPer Study Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2018 Jul 26;379(4):315-326.
|
||
doi: 10.1056/NEJMoa1802345.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30044935" target="_blank">30044935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28349655">Review in peeling complications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Costa IMC,
|
||
Damasceno PS,
|
||
Costa MC,
|
||
Gomes KGP</span><br />
|
||
<span class="medgenPMjournal">J Cosmet Dermatol</span>
|
||
2017 Sep;16(3):319-326.
|
||
Epub 2017 Mar 27
|
||
doi: 10.1111/jocd.12329.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28349655" target="_blank">28349655</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23243113">American Medical Society for Sports Medicine position statement: concussion in sport.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harmon KG,
|
||
Drezner JA,
|
||
Gammons M,
|
||
Guskiewicz KM,
|
||
Halstead M,
|
||
Herring SA,
|
||
Kutcher JS,
|
||
Pana A,
|
||
Putukian M,
|
||
Roberts WO</span><br />
|
||
<span class="medgenPMjournal">Br J Sports Med</span>
|
||
2013 Jan;47(1):15-26.
|
||
doi: 10.1136/bjsports-2012-091941.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23243113" target="_blank">23243113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2258960">Nonoperative management of blunt liver injuries in adults: the need for continued surveillance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Knudson MM,
|
||
Lim RC Jr,
|
||
Oakes DD,
|
||
Jeffrey RB Jr</span><br />
|
||
<span class="medgenPMjournal">J Trauma</span>
|
||
1990 Dec;30(12):1494-500.
|
||
doi: 10.1097/00005373-199012000-00009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2258960" target="_blank">2258960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Persistent%20bleeding%20after%20trauma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (564)</a></div><h3 class="subhead">Diagnosis</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/34853362">Early brain injury and cognitive impairment after aneurysmal subarachnoid haemorrhage.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Rowland MJ,
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Garry P,
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Ezra M,
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Corkill R,
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Baker I,
|
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Jezzard P,
|
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Westbrook J,
|
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Douaud G,
|
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Pattinson KTS</span><br />
|
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<span class="medgenPMjournal">Sci Rep</span>
|
||
2021 Dec 1;11(1):23245.
|
||
doi: 10.1038/s41598-021-02539-x.
|
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<span class="bold">PMID: </span><a href="/pubmed/34853362" target="_blank">34853362</a><a href="/pmc/articles/PMC8636506" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/30661258">Motor behavior unmasks residual cognition in disorders of consciousness.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Pincherle A,
|
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Jöhr J,
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Chatelle C,
|
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Pignat JM,
|
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Du Pasquier R,
|
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Ryvlin P,
|
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Oddo M,
|
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Diserens K</span><br />
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<span class="medgenPMjournal">Ann Neurol</span>
|
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2019 Mar;85(3):443-447.
|
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Epub 2019 Feb 10
|
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doi: 10.1002/ana.25417.
|
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<span class="bold">PMID: </span><a href="/pubmed/30661258" target="_blank">30661258</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23773881">Dilemmas in distinguishing between tumor and the posttraumatic lesion with surgical or pathologic correlation.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Walker E,
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Brian P,
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Longo V,
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Fox EJ,
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Frauenhoffer EE,
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Murphey M</span><br />
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<span class="medgenPMjournal">Clin Sports Med</span>
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2013 Jul;32(3):559-76.
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Epub 2013 May 8
|
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doi: 10.1016/j.csm.2013.03.008.
|
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<span class="bold">PMID: </span><a href="/pubmed/23773881" target="_blank">23773881</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/23243113">American Medical Society for Sports Medicine position statement: concussion in sport.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Harmon KG,
|
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Drezner JA,
|
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Gammons M,
|
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Guskiewicz KM,
|
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Halstead M,
|
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Herring SA,
|
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Kutcher JS,
|
||
Pana A,
|
||
Putukian M,
|
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Roberts WO</span><br />
|
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<span class="medgenPMjournal">Br J Sports Med</span>
|
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2013 Jan;47(1):15-26.
|
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doi: 10.1136/bjsports-2012-091941.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23243113" target="_blank">23243113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20817498">Treatment of haemothorax.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Boersma WG,
|
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Stigt JA,
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Smit HJ</span><br />
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<span class="medgenPMjournal">Respir Med</span>
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2010 Nov;104(11):1583-7.
|
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doi: 10.1016/j.rmed.2010.08.006.
|
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<span class="bold">PMID: </span><a href="/pubmed/20817498" target="_blank">20817498</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Persistent%20bleeding%20after%20trauma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (432)</a></div><h3 class="subhead">Therapy</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/32859839">Subdural Hematoma Related to Dural Tear During Lumbar Spine Surgery: A Case Report and Review of the Literature.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Oktay K</span><br />
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<span class="medgenPMjournal">Neurol India</span>
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2020 Jul-Aug;68(4):903-905.
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doi: 10.4103/0028-3886.293459.
|
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<span class="bold">PMID: </span><a href="/pubmed/32859839" target="_blank">32859839</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30044935">Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sperry JL,
|
||
Guyette FX,
|
||
Brown JB,
|
||
Yazer MH,
|
||
Triulzi DJ,
|
||
Early-Young BJ,
|
||
Adams PW,
|
||
Daley BJ,
|
||
Miller RS,
|
||
Harbrecht BG,
|
||
Claridge JA,
|
||
Phelan HA,
|
||
Witham WR,
|
||
Putnam AT,
|
||
Duane TM,
|
||
Alarcon LH,
|
||
Callaway CW,
|
||
Zuckerbraun BS,
|
||
Neal MD,
|
||
Rosengart MR,
|
||
Forsythe RM,
|
||
Billiar TR,
|
||
Yealy DM,
|
||
Peitzman AB,
|
||
Zenati MS;
|
||
PAMPer Study Group</span><br />
|
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<span class="medgenPMjournal">N Engl J Med</span>
|
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2018 Jul 26;379(4):315-326.
|
||
doi: 10.1056/NEJMoa1802345.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30044935" target="_blank">30044935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28349655">Review in peeling complications.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Costa IMC,
|
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Damasceno PS,
|
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Costa MC,
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Gomes KGP</span><br />
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<span class="medgenPMjournal">J Cosmet Dermatol</span>
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2017 Sep;16(3):319-326.
|
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Epub 2017 Mar 27
|
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doi: 10.1111/jocd.12329.
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<span class="bold">PMID: </span><a href="/pubmed/28349655" target="_blank">28349655</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25663775">Intragastric band erosion: experiences with gastrointestinal endoscopic removal.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aarts EO,
|
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van Wageningen B,
|
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Berends F,
|
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Janssen I,
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Wahab P,
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Groenen M</span><br />
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<span class="medgenPMjournal">World J Gastroenterol</span>
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2015 Feb 7;21(5):1567-72.
|
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doi: 10.3748/wjg.v21.i5.1567.
|
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<span class="bold">PMID: </span><a href="/pubmed/25663775" target="_blank">25663775</a><a href="/pmc/articles/PMC4316098" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20817498">Treatment of haemothorax.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boersma WG,
|
||
Stigt JA,
|
||
Smit HJ</span><br />
|
||
<span class="medgenPMjournal">Respir Med</span>
|
||
2010 Nov;104(11):1583-7.
|
||
doi: 10.1016/j.rmed.2010.08.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20817498" target="_blank">20817498</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Persistent%20bleeding%20after%20trauma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (435)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34863377">Surgical Treatment for Osteochondral Lesions of the Talus.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Powers RT,
|
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Dowd TC,
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Giza E</span><br />
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<span class="medgenPMjournal">Arthroscopy</span>
|
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2021 Dec;37(12):3393-3396.
|
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doi: 10.1016/j.arthro.2021.10.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34863377" target="_blank">34863377</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34853362">Early brain injury and cognitive impairment after aneurysmal subarachnoid haemorrhage.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rowland MJ,
|
||
Garry P,
|
||
Ezra M,
|
||
Corkill R,
|
||
Baker I,
|
||
Jezzard P,
|
||
Westbrook J,
|
||
Douaud G,
|
||
Pattinson KTS</span><br />
|
||
<span class="medgenPMjournal">Sci Rep</span>
|
||
2021 Dec 1;11(1):23245.
|
||
doi: 10.1038/s41598-021-02539-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34853362" target="_blank">34853362</a><a href="/pmc/articles/PMC8636506" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30661258">Motor behavior unmasks residual cognition in disorders of consciousness.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pincherle A,
|
||
Jöhr J,
|
||
Chatelle C,
|
||
Pignat JM,
|
||
Du Pasquier R,
|
||
Ryvlin P,
|
||
Oddo M,
|
||
Diserens K</span><br />
|
||
<span class="medgenPMjournal">Ann Neurol</span>
|
||
2019 Mar;85(3):443-447.
|
||
Epub 2019 Feb 10
|
||
doi: 10.1002/ana.25417.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30661258" target="_blank">30661258</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23243113">American Medical Society for Sports Medicine position statement: concussion in sport.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harmon KG,
|
||
Drezner JA,
|
||
Gammons M,
|
||
Guskiewicz KM,
|
||
Halstead M,
|
||
Herring SA,
|
||
Kutcher JS,
|
||
Pana A,
|
||
Putukian M,
|
||
Roberts WO</span><br />
|
||
<span class="medgenPMjournal">Br J Sports Med</span>
|
||
2013 Jan;47(1):15-26.
|
||
doi: 10.1136/bjsports-2012-091941.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23243113" target="_blank">23243113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2258960">Nonoperative management of blunt liver injuries in adults: the need for continued surveillance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Knudson MM,
|
||
Lim RC Jr,
|
||
Oakes DD,
|
||
Jeffrey RB Jr</span><br />
|
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<span class="medgenPMjournal">J Trauma</span>
|
||
1990 Dec;30(12):1494-500.
|
||
doi: 10.1097/00005373-199012000-00009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2258960" target="_blank">2258960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Persistent%20bleeding%20after%20trauma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (345)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38050397">Chronic subdural haematoma mimicking extrapyramidal symptoms.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Cheng PW,
|
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Tsai RA,
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Lee CH,
|
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Chen WC</span><br />
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<span class="medgenPMjournal">BMJ Case Rep</span>
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2023 Dec 1;16(12)
|
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doi: 10.1136/bcr-2023-255286.
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<span class="bold">PMID: </span><a href="/pubmed/38050397" target="_blank">38050397</a><a href="/pmc/articles/PMC10693859" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33646273">Recovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kowalski RG,
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Hammond FM,
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Weintraub AH,
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Nakase-Richardson R,
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Zafonte RD,
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Whyte J,
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Giacino JT</span><br />
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<span class="medgenPMjournal">JAMA Neurol</span>
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2021 May 1;78(5):548-557.
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doi: 10.1001/jamaneurol.2021.0084.
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<span class="bold">PMID: </span><a href="/pubmed/33646273" target="_blank">33646273</a><a href="/pmc/articles/PMC7922241" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30044935">Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sperry JL,
|
||
Guyette FX,
|
||
Brown JB,
|
||
Yazer MH,
|
||
Triulzi DJ,
|
||
Early-Young BJ,
|
||
Adams PW,
|
||
Daley BJ,
|
||
Miller RS,
|
||
Harbrecht BG,
|
||
Claridge JA,
|
||
Phelan HA,
|
||
Witham WR,
|
||
Putnam AT,
|
||
Duane TM,
|
||
Alarcon LH,
|
||
Callaway CW,
|
||
Zuckerbraun BS,
|
||
Neal MD,
|
||
Rosengart MR,
|
||
Forsythe RM,
|
||
Billiar TR,
|
||
Yealy DM,
|
||
Peitzman AB,
|
||
Zenati MS;
|
||
PAMPer Study Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2018 Jul 26;379(4):315-326.
|
||
doi: 10.1056/NEJMoa1802345.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30044935" target="_blank">30044935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23243113">American Medical Society for Sports Medicine position statement: concussion in sport.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harmon KG,
|
||
Drezner JA,
|
||
Gammons M,
|
||
Guskiewicz KM,
|
||
Halstead M,
|
||
Herring SA,
|
||
Kutcher JS,
|
||
Pana A,
|
||
Putukian M,
|
||
Roberts WO</span><br />
|
||
<span class="medgenPMjournal">Br J Sports Med</span>
|
||
2013 Jan;47(1):15-26.
|
||
doi: 10.1136/bjsports-2012-091941.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23243113" target="_blank">23243113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20817498">Treatment of haemothorax.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boersma WG,
|
||
Stigt JA,
|
||
Smit HJ</span><br />
|
||
<span class="medgenPMjournal">Respir Med</span>
|
||
2010 Nov;104(11):1583-7.
|
||
doi: 10.1016/j.rmed.2010.08.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20817498" target="_blank">20817498</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Persistent%20bleeding%20after%20trauma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (330)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37270200">School-age outcomes of children after perinatal brain injury: a systematic review and meta-analysis.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Rees P,
|
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Callan C,
|
||
Chadda K,
|
||
Vaal M,
|
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Diviney J,
|
||
Sabti S,
|
||
Harnden F,
|
||
Gardiner J,
|
||
Battersby C,
|
||
Gale C,
|
||
Sutcliffe A</span><br />
|
||
<span class="medgenPMjournal">BMJ Paediatr Open</span>
|
||
2023 Jun;7(1)
|
||
doi: 10.1136/bmjpo-2022-001810.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37270200" target="_blank">37270200</a><a href="/pmc/articles/PMC10255042" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34789643">Surgical Strategies for Cardiac Perforation After Catheter Ablation or Electrophysiology Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wu SJ,
|
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Fan YF,
|
||
Chien CY</span><br />
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<span class="medgenPMjournal">Int Heart J</span>
|
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2021 Nov 30;62(6):1257-1264.
|
||
Epub 2021 Nov 17
|
||
doi: 10.1536/ihj.21-201.
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||
<span class="bold">PMID: </span><a href="/pubmed/34789643" target="_blank">34789643</a></div>
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||
|
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<div class="nl"><a target="_blank" href="/pubmed/27739945">Blunt prenatal trauma resulting in fetal epidural or subdural hematoma: case report and systematic review of the literature.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Joseph JR,
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Smith BW,
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Garton HJ</span><br />
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<span class="medgenPMjournal">J Neurosurg Pediatr</span>
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2017 Jan;19(1):32-37.
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Epub 2016 Oct 14
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doi: 10.3171/2016.7.PEDS16282.
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||
<span class="bold">PMID: </span><a href="/pubmed/27739945" target="_blank">27739945</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23553352">Video-assisted thoracoscopy as an important tool for trauma surgeons: a systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Billeter AT,
|
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Druen D,
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Franklin GA,
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Smith JW,
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Wrightson W,
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Richardson JD</span><br />
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<span class="medgenPMjournal">Langenbecks Arch Surg</span>
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2013 Apr;398(4):515-23.
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Epub 2013 Apr 4
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doi: 10.1007/s00423-012-1016-7.
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||
<span class="bold">PMID: </span><a href="/pubmed/23553352" target="_blank">23553352</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23363882">Newborn retinal hemorrhages: a systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Watts P,
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Maguire S,
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Kwok T,
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Talabani B,
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Mann M,
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Wiener J,
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Lawson Z,
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Kemp A</span><br />
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<span class="medgenPMjournal">J AAPOS</span>
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2013 Feb;17(1):70-8.
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Epub 2013 Jan 28
|
||
doi: 10.1016/j.jaapos.2012.07.012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23363882" target="_blank">23363882</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Persistent%20bleeding%20after%20trauma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1844374%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (8)</a></li>
|
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<li><a href="/gtr/tests?term=C1844374%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (8)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C1844374%5bDISCUI%5d" target="_blank">See all (8)</a></total></li>
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