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<meta name="keywords" content="C1836742, absent brainstem auditory responses, finding, no auditory brainstem response, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Lack of measurable response to stimulation of auditory evoked potentials." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Absent brainstem auditory responses (Concept Id: C1836742)
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<!--
UID=322983
ConceptID=C1836742
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Absent brainstem auditory responses</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>322983</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1836742</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>No auditory brainstem response</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0004463">HP:0004463</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Lack of measurable response to stimulation of auditory evoked potentials. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Absent brainstem auditory responses</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868417" ref="tree=MeSH" title="MedGen record for Abnormal nervous system physiology">Abnormal nervous system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/867410" ref="tree=MeSH" title="MedGen record for Abnormal nervous system electrophysiology">Abnormal nervous system electrophysiology</a></span><ul><li><span class="TLline"><a href="/medgen/868205" ref="tree=MeSH" title="MedGen record for Abnormality of central nervous system electrophysiology">Abnormality of central nervous system electrophysiology</a></span><ul><li><span class="TLline"><a href="/medgen/1863529" ref="tree=MeSH" title="MedGen record for Abnormal brain-evoked potentials">Abnormal brain-evoked potentials</a></span><ul><li><span class="TLline"><a href="/medgen/141758" ref="tree=MeSH" title="MedGen record for Abnormal auditory evoked potentials">Abnormal auditory evoked potentials</a></span><ul><li><span class="matched_ds">Absent brainstem auditory responses</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_331376"><div><strong>Autosomal recessive nonsyndromic hearing loss 9</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>331376</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C1832828</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">OTOF-related deafness is characterized by two phenotypes: prelingual nonsyndromic auditory neuropathy spectrum disorder (ANSD) and, less frequently, temperature-sensitive auditory neuropathy spectrum disorder (TS-ANSD). OTOF-related ANSD is characterized by congenital or prelingual, typically severe-to-profound bilateral deafness without inner-ear anomalies on MRI or CT examination of the temporal bones. Otoacoustic emissions (OAEs) are present and auditory brain stem response is abnormal at birth. Newborn hearing screening testing of OAEs only will fail to detect this disorder in most individuals. OAEs may decrease or disappear with age in 20%-80% of individuals. TS-ANSD typically presents with normal-to-moderate hearing loss (0-55 dB) at baseline body temperature. An elevation of body temperature (approximately 0.5°C or more) triggers significant bilateral hearing loss ranging from severe to profound, with resolution of hearing loss typically occurring within hours of a return to baseline body temperature.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/331376">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_373160"><div><strong>PCWH syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>373160</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1836727</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">PCWH syndrome is a complex neurocristopathy that includes features of 4 distinct syndromes: peripheral demyelinating neuropathy (see 118200), central dysmyelination, Waardenburg syndrome, and Hirschsprung disease (see 142623) (Inoue et al., 2004). Inoue et al. (2004) proposed the acronym PCWH for this disorder.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/373160">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_899775"><div><strong>Autosomal recessive nonsyndromic hearing loss 104</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>899775</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4225298</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the RIPOR2 gene.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/899775">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1382171"><div><strong>Neurodevelopmental disorder with hypotonia, neuropathy, and deafness</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1382171</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4479603</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">SPTBN4 disorder is typically characterized by severe-to-profound developmental delay and/or intellectual disability, although two individuals in one family had a milder phenotype, including one individual with normal cognitive development. Speech and language skills are often severely limited. Affected individuals rarely achieve head control. Most are unable to sit, stand, or walk. Affected individuals typically have congenital hypotonia that may transition to hypertonia. Axonal motor neuropathy leads to hyporeflexia/areflexia and weakness, which can result in respiratory difficulties requiring ventilatory support. Most affected individuals require tube feeding for nutrition. Half of affected individuals develop seizures. Cortical visual impairment and auditory neuropathy have also been reported.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1382171">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_899775" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive nonsyndromic hearing loss 104</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_331376" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive nonsyndromic hearing loss 9</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1382171" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurodevelopmental disorder with hypotonia, neuropathy, and deafness</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_373160" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">PCWH syndrome</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/24380663">Auditory dyssynchrony or auditory neuropathy: understanding the pathophysiology and exploring methods of treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nikolopoulos TP</span><br />
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
2014 Feb;78(2):171-3.
Epub 2013 Dec 24
doi: 10.1016/j.ijporl.2013.12.021.
<span class="bold">PMID: </span><a href="/pubmed/24380663" target="_blank">24380663</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21596446">Auditory neuropathy/dyssynchrony as a cause of failed neonatal hearing screening.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maris M,
Venstermans C,
Boudewyns AN</span><br />
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
2011 Jul;75(7):973-5.
Epub 2011 May 19
doi: 10.1016/j.ijporl.2011.04.012.
<span class="bold">PMID: </span><a href="/pubmed/21596446" target="_blank">21596446</a></div>
<div class="nl"><a target="_blank" href="/pubmed/18502518">Auditory neuropathy: endocochlear lesion or temporal processing impairment? Implications for diagnosis and management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vlastarakos PV,
Nikolopoulos TP,
Tavoulari E,
Papacharalambous G,
Korres S</span><br />
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
2008 Aug;72(8):1135-50.
Epub 2008 May 27
doi: 10.1016/j.ijporl.2008.04.004.
<span class="bold">PMID: </span><a href="/pubmed/18502518" target="_blank">18502518</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22absent%20brainstem%20auditory%20responses%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (5)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/33866399">Cochlear implantation versus auditory brainstem implantation in children with auditory nerve deficiencies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yousef M,
Mesallam TA,
Almasaad A,
Alhabib S,
Hagr A,
Alzhrani F</span><br />
<span class="medgenPMjournal">Eur Arch Otorhinolaryngol</span>
2022 Mar;279(3):1295-1300.
Epub 2021 Apr 18
doi: 10.1007/s00405-021-06792-8.
<span class="bold">PMID: </span><a href="/pubmed/33866399" target="_blank">33866399</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33184036">Click-evoked and speech-evoked auditory brainstem responses from individuals with multiple sclerosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rishiq D,
Harkrider A,
Springer C,
Hedrick M</span><br />
<span class="medgenPMjournal">Neurosci Lett</span>
2021 Jan 1;740:135460.
Epub 2020 Oct 24
doi: 10.1016/j.neulet.2020.135460.
<span class="bold">PMID: </span><a href="/pubmed/33184036" target="_blank">33184036</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26209259">Auditory nerve disease and auditory neuropathy spectrum disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kaga K</span><br />
<span class="medgenPMjournal">Auris Nasus Larynx</span>
2016 Feb;43(1):10-20.
Epub 2015 Jul 22
doi: 10.1016/j.anl.2015.06.008.
<span class="bold">PMID: </span><a href="/pubmed/26209259" target="_blank">26209259</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24380663">Auditory dyssynchrony or auditory neuropathy: understanding the pathophysiology and exploring methods of treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nikolopoulos TP</span><br />
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
2014 Feb;78(2):171-3.
Epub 2013 Dec 24
doi: 10.1016/j.ijporl.2013.12.021.
<span class="bold">PMID: </span><a href="/pubmed/24380663" target="_blank">24380663</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12972945">Familial auditory neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Q,
Gu R,
Han D,
Yang W</span><br />
<span class="medgenPMjournal">Laryngoscope</span>
2003 Sep;113(9):1623-9.
doi: 10.1097/00005537-200309000-00041.
<span class="bold">PMID: </span><a href="/pubmed/12972945" target="_blank">12972945</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Absent%20brainstem%20auditory%20responses%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (144)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/33658211">Case of oculo-auriculo-vertebral spectrum: rare clinical features.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Khera D,
Agarwal S,
Kumar P,
Singh K</span><br />
<span class="medgenPMjournal">BMJ Case Rep</span>
2021 Mar 3;14(3)
doi: 10.1136/bcr-2019-234181.
<span class="bold">PMID: </span><a href="/pubmed/33658211" target="_blank">33658211</a><a href="/pmc/articles/PMC7931756" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32761206">Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Greer DM,
Shemie SD,
Lewis A,
Torrance S,
Varelas P,
Goldenberg FD,
Bernat JL,
Souter M,
Topcuoglu MA,
Alexandrov AW,
Baldisseri M,
Bleck T,
Citerio G,
Dawson R,
Hoppe A,
Jacobe S,
Manara A,
Nakagawa TA,
Pope TM,
Silvester W,
Thomson D,
Al Rahma H,
Badenes R,
Baker AJ,
Cerny V,
Chang C,
Chang TR,
Gnedovskaya E,
Han MK,
Honeybul S,
Jimenez E,
Kuroda Y,
Liu G,
Mallick UK,
Marquevich V,
Mejia-Mantilla J,
Piradov M,
Quayyum S,
Shrestha GS,
Su YY,
Timmons SD,
Teitelbaum J,
Videtta W,
Zirpe K,
Sung G</span><br />
<span class="medgenPMjournal">JAMA</span>
2020 Sep 15;324(11):1078-1097.
doi: 10.1001/jama.2020.11586.
<span class="bold">PMID: </span><a href="/pubmed/32761206" target="_blank">32761206</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31277868">Auditory brainstem response.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Eggermont JJ</span><br />
<span class="medgenPMjournal">Handb Clin Neurol</span>
2019;160:451-464.
doi: 10.1016/B978-0-444-64032-1.00030-8.
<span class="bold">PMID: </span><a href="/pubmed/31277868" target="_blank">31277868</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30531641">Phenotypic Characterization of DFNB16-associated Hearing Loss.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Back D,
Shehata-Dieler W,
Vona B,
Hofrichter MAH,
Schroeder J,
Haaf T,
Rahne T,
Hagen R,
Schraven SP</span><br />
<span class="medgenPMjournal">Otol Neurotol</span>
2019 Jan;40(1):e48-e55.
doi: 10.1097/MAO.0000000000002059.
<span class="bold">PMID: </span><a href="/pubmed/30531641" target="_blank">30531641</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25090808">Auditory neuropathy/dyssynchrony revisited.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Menten K,
Van Eynde C,
Desloovere C,
Wouters J</span><br />
<span class="medgenPMjournal">B-ENT</span>
2014;10(2):105-12.
<span class="bold">PMID: </span><a href="/pubmed/25090808" target="_blank">25090808</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Absent%20brainstem%20auditory%20responses%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (241)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/34751677">Auditory Brainstem Response Detection Using Machine Learning: A Comparison With Statistical Detection Methods.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McKearney RM,
Bell SL,
Chesnaye MA,
Simpson DM</span><br />
<span class="medgenPMjournal">Ear Hear</span>
2022 May/Jun;43(3):949-960.
doi: 10.1097/AUD.0000000000001151.
<span class="bold">PMID: </span><a href="/pubmed/34751677" target="_blank">34751677</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32761206">Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Greer DM,
Shemie SD,
Lewis A,
Torrance S,
Varelas P,
Goldenberg FD,
Bernat JL,
Souter M,
Topcuoglu MA,
Alexandrov AW,
Baldisseri M,
Bleck T,
Citerio G,
Dawson R,
Hoppe A,
Jacobe S,
Manara A,
Nakagawa TA,
Pope TM,
Silvester W,
Thomson D,
Al Rahma H,
Badenes R,
Baker AJ,
Cerny V,
Chang C,
Chang TR,
Gnedovskaya E,
Han MK,
Honeybul S,
Jimenez E,
Kuroda Y,
Liu G,
Mallick UK,
Marquevich V,
Mejia-Mantilla J,
Piradov M,
Quayyum S,
Shrestha GS,
Su YY,
Timmons SD,
Teitelbaum J,
Videtta W,
Zirpe K,
Sung G</span><br />
<span class="medgenPMjournal">JAMA</span>
2020 Sep 15;324(11):1078-1097.
doi: 10.1001/jama.2020.11586.
<span class="bold">PMID: </span><a href="/pubmed/32761206" target="_blank">32761206</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32290759">Acquired auditory neuropathy spectrum disorder after malaria treated with quinine.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Brough H</span><br />
<span class="medgenPMjournal">Trop Doct</span>
2020 Jul;50(3):246-248.
Epub 2020 Apr 14
doi: 10.1177/0049475520917236.
<span class="bold">PMID: </span><a href="/pubmed/32290759" target="_blank">32290759</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25627996">Effects of auditory training in individuals with high-frequency hearing loss.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Santos RB,
Marangoni AT,
de Andrade AN,
Prestes R,
Gil D</span><br />
<span class="medgenPMjournal">Clinics (Sao Paulo)</span>
2014;69(12):835-40.
doi: 10.6061/clinics/2014(12)08.
<span class="bold">PMID: </span><a href="/pubmed/25627996" target="_blank">25627996</a><a href="/pmc/articles/PMC4286663" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21532477">Brainstem responses can predict death and delirium in sedated patients in intensive care unit.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sharshar T,
Porcher R,
Siami S,
Rohaut B,
Bailly-Salin J,
Hopkinson NS,
Clair B,
Guidoux C,
Iacobone E,
Sonneville R,
Polito A,
Aboab J,
Gaudry S,
Morla O,
Amouyal G,
Azuar J,
Allary J,
Vieillard-Baron A,
Wolff M,
Cariou A,
Annane D;
Paris-Ouest Study Group on Neurological Effect of Sedation (POSGNES)</span><br />
<span class="medgenPMjournal">Crit Care Med</span>
2011 Aug;39(8):1960-7.
doi: 10.1097/CCM.0b013e31821b843b.
<span class="bold">PMID: </span><a href="/pubmed/21532477" target="_blank">21532477</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Absent%20brainstem%20auditory%20responses%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (43)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37195321">Pathophysiological and Clinical Aspects of Hearing Loss Among 85-Year-Olds.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Göthberg H,
Skoog I,
Tengstrand T,
Magnusson L,
Hoff M,
Rosenhall U,
Sadeghi A</span><br />
<span class="medgenPMjournal">Am J Audiol</span>
2023 Jun;32(2):440-452.
Epub 2023 May 17
doi: 10.1044/2023_AJA-22-00214.
<span class="bold">PMID: </span><a href="/pubmed/37195321" target="_blank">37195321</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33417382">Multimodal Evoked Potential Profiles in Woodhouse-Sakati Syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abusrair A,
AlHamoud I,
Bohlega S</span><br />
<span class="medgenPMjournal">J Clin Neurophysiol</span>
2022 Sep 1;39(6):504-509.
Epub 2020 Dec 30
doi: 10.1097/WNP.0000000000000811.
<span class="bold">PMID: </span><a href="/pubmed/33417382" target="_blank">33417382</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33964333">Prognostic value of brainstem auditory and visual evoked potentials in cardiac arrest patients with targeted temperature management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lim JY,
Oh SH,
Park KN,
Choi SP,
Oh JS,
Youn CS,
Kim HJ,
Kim HJ,
Song H</span><br />
<span class="medgenPMjournal">Resuscitation</span>
2021 Jul;164:12-19.
Epub 2021 May 5
doi: 10.1016/j.resuscitation.2021.04.024.
<span class="bold">PMID: </span><a href="/pubmed/33964333" target="_blank">33964333</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25798647">Prognostic value of electrically evoked auditory brainstem responses in cochlear implantation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lundin K,
Stillesjö F,
Rask-Andersen H</span><br />
<span class="medgenPMjournal">Cochlear Implants Int</span>
2015 Sep;16(5):254-61.
Epub 2015 Mar 23
doi: 10.1179/1754762815Y.0000000005.
<span class="bold">PMID: </span><a href="/pubmed/25798647" target="_blank">25798647</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21532477">Brainstem responses can predict death and delirium in sedated patients in intensive care unit.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sharshar T,
Porcher R,
Siami S,
Rohaut B,
Bailly-Salin J,
Hopkinson NS,
Clair B,
Guidoux C,
Iacobone E,
Sonneville R,
Polito A,
Aboab J,
Gaudry S,
Morla O,
Amouyal G,
Azuar J,
Allary J,
Vieillard-Baron A,
Wolff M,
Cariou A,
Annane D;
Paris-Ouest Study Group on Neurological Effect of Sedation (POSGNES)</span><br />
<span class="medgenPMjournal">Crit Care Med</span>
2011 Aug;39(8):1960-7.
doi: 10.1097/CCM.0b013e31821b843b.
<span class="bold">PMID: </span><a href="/pubmed/21532477" target="_blank">21532477</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Absent%20brainstem%20auditory%20responses%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (76)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/33866399">Cochlear implantation versus auditory brainstem implantation in children with auditory nerve deficiencies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yousef M,
Mesallam TA,
Almasaad A,
Alhabib S,
Hagr A,
Alzhrani F</span><br />
<span class="medgenPMjournal">Eur Arch Otorhinolaryngol</span>
2022 Mar;279(3):1295-1300.
Epub 2021 Apr 18
doi: 10.1007/s00405-021-06792-8.
<span class="bold">PMID: </span><a href="/pubmed/33866399" target="_blank">33866399</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32761206">Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Greer DM,
Shemie SD,
Lewis A,
Torrance S,
Varelas P,
Goldenberg FD,
Bernat JL,
Souter M,
Topcuoglu MA,
Alexandrov AW,
Baldisseri M,
Bleck T,
Citerio G,
Dawson R,
Hoppe A,
Jacobe S,
Manara A,
Nakagawa TA,
Pope TM,
Silvester W,
Thomson D,
Al Rahma H,
Badenes R,
Baker AJ,
Cerny V,
Chang C,
Chang TR,
Gnedovskaya E,
Han MK,
Honeybul S,
Jimenez E,
Kuroda Y,
Liu G,
Mallick UK,
Marquevich V,
Mejia-Mantilla J,
Piradov M,
Quayyum S,
Shrestha GS,
Su YY,
Timmons SD,
Teitelbaum J,
Videtta W,
Zirpe K,
Sung G</span><br />
<span class="medgenPMjournal">JAMA</span>
2020 Sep 15;324(11):1078-1097.
doi: 10.1001/jama.2020.11586.
<span class="bold">PMID: </span><a href="/pubmed/32761206" target="_blank">32761206</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23895952">Positive auditory cortical responses in patients with absent brainstem response.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kawase T,
Kanno A,
Takata Y,
Nakasato N,
Kawashima R,
Kobayashi T</span><br />
<span class="medgenPMjournal">Clin Neurophysiol</span>
2014 Jan;125(1):148-53.
Epub 2013 Jul 26
doi: 10.1016/j.clinph.2013.06.184.
<span class="bold">PMID: </span><a href="/pubmed/23895952" target="_blank">23895952</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22201801">Genetics of isolated auditory neuropathies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Del Castillo FJ,
Del Castillo I</span><br />
<span class="medgenPMjournal">Front Biosci (Landmark Ed)</span>
2012 Jan 1;17(4):1251-65.
doi: 10.2741/3984.
<span class="bold">PMID: </span><a href="/pubmed/22201801" target="_blank">22201801</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12972945">Familial auditory neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Q,
Gu R,
Han D,
Yang W</span><br />
<span class="medgenPMjournal">Laryngoscope</span>
2003 Sep;113(9):1623-9.
doi: 10.1097/00005537-200309000-00041.
<span class="bold">PMID: </span><a href="/pubmed/12972945" target="_blank">12972945</a></div>
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