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<!--
|
||
UID=318834
|
||
ConceptID=C1833297
|
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Frontal release signs</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>318834</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1833297</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Frontal release reflexes</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000743">HP:0000743</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Primitive reflexes traditionally held to be a sign of disorders that affect the frontal lobes. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Frontal release signs</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/871309" ref="tree=MeSH" title="MedGen record for Abnormality of prenatal development or birth">Abnormality of prenatal development or birth</a></span><ul><li><span class="TLline"><a href="/medgen/1254" ref="tree=MeSH" title="MedGen record for Fetal anomaly">Fetal anomaly</a></span><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868417" ref="tree=MeSH" title="MedGen record for Abnormal nervous system physiology">Abnormal nervous system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/10113" ref="tree=MeSH" title="MedGen record for Movement disorder">Movement disorder</a></span><ul><li><span class="matched_ds">Frontal release signs</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_318833"><div><strong>Frontotemporal dementia and/or amyotrophic lateral sclerosis 7</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>318833</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1833296</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">CHMP2B frontotemporal dementia (CHMP2B-FTD) has been described in a single family from Denmark, in one individual with familial FTD from Belgium, and in one individual with FTD and no family history. It typically starts between ages 46 and 65 years with subtle personality changes and slowly progressive behavioral changes, dysexecutive syndrome, dyscalculia, and language disturbances. Disinhibition or loss of initiative is the most common presenting symptom. The disease progresses over a few years into profound dementia with extrapyramidal symptoms and mutism. Several individuals have developed an asymmetric akinetic rigid syndrome with arm and gait dystonia and pyramidal signs that may be related to treatment with neuroleptic drugs. Symptoms and disease course are highly variable. Disease duration may be as short as three years or longer than 20 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/318833">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_324446"><div><strong>Supranuclear palsy, progressive, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>324446</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1836148</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/324446">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_337637"><div><strong>Spinocerebellar ataxia type 17</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>337637</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1846707</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Spinocerebellar ataxia type 17 (SCA17) is characterized by ataxia, dementia, and involuntary movements, including chorea and dystonia. Psychiatric symptoms, pyramidal signs, and rigidity are common. The age of onset ranges from three to 55 years. Individuals with full-penetrance alleles develop neurologic and/or psychiatric symptoms by age 50 years. Ataxia and psychiatric abnormalities are frequently the initial findings, followed by involuntary movement, parkinsonism, dementia, and pyramidal signs. Brain MRI shows variable atrophy of the cerebrum, brain stem, and cerebellum. The clinical features correlate with the length of the polyglutamine expansion but are not absolutely predictive of the clinical course.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/337637">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_763887"><div><strong>Neurodegeneration with brain iron accumulation 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>763887</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3550973</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Beta-propeller protein-associated neurodegeneration (BPAN) is typically characterized by early-onset seizures, infantile-onset developmental delay, intellectual disability, absent-to-limited expressive language, motor dysfunction (ataxia), and abnormal behaviors often similar to autism spectrum disorder. Seizure types including generalized (absence, tonic, atonic, tonic-clonic and myoclonic), focal with impaired consciousness, and epileptic spasms, as well as epileptic syndromes (West syndrome and Lennox-Gastaut syndrome) can be seen. With age seizures tend to resolve or become less prominent, whereas cognitive decline and movement disorders (progressive parkinsonism and dystonia) emerge as characteristic findings.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/763887">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1640811"><div><strong>Supranuclear palsy, progressive, 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1640811</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551863</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The spectrum of clinical manifestations of MAPT-related frontotemporal dementia (MAPT-FTD) has expanded from its original description of frontotemporal dementia and parkinsonian manifestations to include changes in behavior, motor function, memory, and/or language. A recent retrospective study suggested that the majority of affected individuals have either behavioral changes consistent with a diagnosis of behavioral variant FTD (bvFTD) or, less commonly, a parkinsonian syndrome (i.e., progressive supranuclear palsy, corticobasal syndrome, or Parkinson disease). Fewer than 5% of people with MAPT-FTD have primary progressive aphasia or Alzheimer disease. Clinical presentation may differ between and within families with the same MAPT variant. MAPT-FTD is a progressive disorder that commonly ends with a relatively global dementia in which some affected individuals become mute. Progression of motor impairment in affected individuals results in some becoming chairbound and others bedbound. Mean disease duration is 9.3 (SD: 6.4) years but is individually variable and can be more than 30 years in some instances.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1640811">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_318833" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Frontotemporal dementia and/or amyotrophic lateral sclerosis 7</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_763887" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurodegeneration with brain iron accumulation 5</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_337637" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Spinocerebellar ataxia type 17</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1640811" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Supranuclear palsy, progressive, 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_324446" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Supranuclear palsy, progressive, 2</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28922069">Glutamatergic Agents in the Treatment of Compulsivity and Impulsivity in Child and Adolescent Psychiatry: a Systematic Review of the Literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mechler K,
|
||
Häge A,
|
||
Schweinfurth N,
|
||
Glennon JC,
|
||
Dijkhuizen RM,
|
||
Murphy D,
|
||
Durston S,
|
||
Williams S,
|
||
K Buitelaar J,
|
||
Banaschewski T,
|
||
Dittmann RW,
|
||
Tactics Consortium T</span><br />
|
||
<span class="medgenPMjournal">Z Kinder Jugendpsychiatr Psychother</span>
|
||
2018 May;46(3):246-263.
|
||
Epub 2017 Sep 18
|
||
doi: 10.1024/1422-4917/a000546.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28922069" target="_blank">28922069</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28882863">Patient Outcomes and Cerebral Infarction after Ruptured Anterior Communicating Artery Aneurysm Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Heit JJ,
|
||
Ball RL,
|
||
Telischak NA,
|
||
Do HM,
|
||
Dodd RL,
|
||
Steinberg GK,
|
||
Chang SD,
|
||
Wintermark M,
|
||
Marks MP</span><br />
|
||
<span class="medgenPMjournal">AJNR Am J Neuroradiol</span>
|
||
2017 Nov;38(11):2119-2125.
|
||
Epub 2017 Sep 7
|
||
doi: 10.3174/ajnr.A5355.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28882863" target="_blank">28882863</a><a href="/pmc/articles/PMC7963583" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22337414">Endoscopic cranial suture release for the treatment of craniosynostosis--is it the future?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Proctor MR</span><br />
|
||
<span class="medgenPMjournal">J Craniofac Surg</span>
|
||
2012 Jan;23(1):225-8.
|
||
doi: 10.1097/SCS.0b013e318241b8f6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22337414" target="_blank">22337414</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(frontal%20release%20signs)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (20)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32444154">Discriminant Performance of Dysexecutive and Frontal Release Signs for Delirium in Patients With High Dementia Prevalence: Implications for Neural Network Impairment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Franco JG,
|
||
Trzepacz PT,
|
||
Velásquez-Tirado JD,
|
||
Ocampo MV,
|
||
Serna PA,
|
||
Giraldo AM,
|
||
López C,
|
||
Zuluaga A,
|
||
Zaraza-Morales D</span><br />
|
||
<span class="medgenPMjournal">J Acad Consult Liaison Psychiatry</span>
|
||
2021 Jan-Feb;62(1):56-69.
|
||
Epub 2020 Apr 13
|
||
doi: 10.1016/j.psym.2020.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32444154" target="_blank">32444154</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28465136">Semantic memory deficits are associated with pica in individuals with acquired brain injury.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Funayama M,
|
||
Muramatsu T,
|
||
Koreki A,
|
||
Kato M,
|
||
Mimura M,
|
||
Nakagawa Y</span><br />
|
||
<span class="medgenPMjournal">Behav Brain Res</span>
|
||
2017 Jun 30;329:172-179.
|
||
Epub 2017 Apr 29
|
||
doi: 10.1016/j.bbr.2017.04.054.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28465136" target="_blank">28465136</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26705121">Progressive supranuclear palsy: progression and survival.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arena JE,
|
||
Weigand SD,
|
||
Whitwell JL,
|
||
Hassan A,
|
||
Eggers SD,
|
||
Höglinger GU,
|
||
Litvan I,
|
||
Josephs KA</span><br />
|
||
<span class="medgenPMjournal">J Neurol</span>
|
||
2016 Feb;263(2):380-389.
|
||
Epub 2015 Dec 24
|
||
doi: 10.1007/s00415-015-7990-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26705121" target="_blank">26705121</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19996256">Subtle neurological signs predict the severity of subacute cognitive and functional impairments after traumatic brain injury.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wortzel HS,
|
||
Frey KL,
|
||
Anderson CA,
|
||
Arciniegas DB</span><br />
|
||
<span class="medgenPMjournal">J Neuropsychiatry Clin Neurosci</span>
|
||
2009 Fall;21(4):463-6.
|
||
doi: 10.1176/jnp.2009.21.4.463.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19996256" target="_blank">19996256</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17666495">Frontal release signs and cognition in people with schizophrenia, their siblings and healthy controls.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hyde TM,
|
||
Goldberg TE,
|
||
Egan MF,
|
||
Lener MC,
|
||
Weinberger DR</span><br />
|
||
<span class="medgenPMjournal">Br J Psychiatry</span>
|
||
2007 Aug;191:120-5.
|
||
doi: 10.1192/bjp.bp.106.026773.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17666495" target="_blank">17666495</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Frontal%20release%20signs%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (21)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37899045">Frontal ataxia: historical aspects and clinical definition.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bonilha PÁAM,
|
||
Cassarotti B,
|
||
Nunes TEM,
|
||
Teive HAG</span><br />
|
||
<span class="medgenPMjournal">Arq Neuropsiquiatr</span>
|
||
2023 Oct;81(10):934-936.
|
||
Epub 2023 Oct 29
|
||
doi: 10.1055/s-0043-1775886.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37899045" target="_blank">37899045</a><a href="/pmc/articles/PMC10631853" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32444154">Discriminant Performance of Dysexecutive and Frontal Release Signs for Delirium in Patients With High Dementia Prevalence: Implications for Neural Network Impairment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Franco JG,
|
||
Trzepacz PT,
|
||
Velásquez-Tirado JD,
|
||
Ocampo MV,
|
||
Serna PA,
|
||
Giraldo AM,
|
||
López C,
|
||
Zuluaga A,
|
||
Zaraza-Morales D</span><br />
|
||
<span class="medgenPMjournal">J Acad Consult Liaison Psychiatry</span>
|
||
2021 Jan-Feb;62(1):56-69.
|
||
Epub 2020 Apr 13
|
||
doi: 10.1016/j.psym.2020.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32444154" target="_blank">32444154</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22674939">VGKC positive autoimmune encephalopathy mimicking dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molloy A,
|
||
Cassidy E,
|
||
Ryan A,
|
||
O' Toole O</span><br />
|
||
<span class="medgenPMjournal">BMJ Case Rep</span>
|
||
2011 Dec 1;2011
|
||
doi: 10.1136/bcr.08.2011.4642.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22674939" target="_blank">22674939</a><a href="/pmc/articles/PMC3229339" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19996256">Subtle neurological signs predict the severity of subacute cognitive and functional impairments after traumatic brain injury.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wortzel HS,
|
||
Frey KL,
|
||
Anderson CA,
|
||
Arciniegas DB</span><br />
|
||
<span class="medgenPMjournal">J Neuropsychiatry Clin Neurosci</span>
|
||
2009 Fall;21(4):463-6.
|
||
doi: 10.1176/jnp.2009.21.4.463.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19996256" target="_blank">19996256</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18835133">Frontal release signs among patients with schizophrenia, their first-degree biological relatives, and non-psychiatric controls.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gabalda MK,
|
||
Weiss PS,
|
||
Compton MT</span><br />
|
||
<span class="medgenPMjournal">Schizophr Res</span>
|
||
2008 Dec;106(2-3):275-80.
|
||
Epub 2008 Oct 2
|
||
doi: 10.1016/j.schres.2008.08.034.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18835133" target="_blank">18835133</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Frontal%20release%20signs%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (29)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/22674939">VGKC positive autoimmune encephalopathy mimicking dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molloy A,
|
||
Cassidy E,
|
||
Ryan A,
|
||
O' Toole O</span><br />
|
||
<span class="medgenPMjournal">BMJ Case Rep</span>
|
||
2011 Dec 1;2011
|
||
doi: 10.1136/bcr.08.2011.4642.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22674939" target="_blank">22674939</a><a href="/pmc/articles/PMC3229339" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22054619">Primitive reflexes associated with delirium: a prospective trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nicolson SE,
|
||
Chabon B,
|
||
Larsen KA,
|
||
Kelly SE,
|
||
Potter AW,
|
||
Stern TA</span><br />
|
||
<span class="medgenPMjournal">Psychosomatics</span>
|
||
2011 Nov-Dec;52(6):507-12.
|
||
doi: 10.1016/j.psym.2011.06.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22054619" target="_blank">22054619</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8648326">Natural history of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) and clinical predictors of survival: a clinicopathological study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Litvan I,
|
||
Mangone CA,
|
||
McKee A,
|
||
Verny M,
|
||
Parsa A,
|
||
Jellinger K,
|
||
D'Olhaberriague L,
|
||
Chaudhuri KR,
|
||
Pearce RK</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
1996 Jun;60(6):615-20.
|
||
doi: 10.1136/jnnp.60.6.615.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8648326" target="_blank">8648326</a><a href="/pmc/articles/PMC1073943" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7854523">Neurologic signs and symptoms in a cohort of homosexual men followed for 4.5 years.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Marder K,
|
||
Liu X,
|
||
Stern Y,
|
||
Dooneief G,
|
||
Bell K,
|
||
Schofield P,
|
||
Sacktor N,
|
||
Todak G,
|
||
Friedman R,
|
||
Ehrhardt A</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
1995 Feb;45(2):261-7.
|
||
doi: 10.1212/wnl.45.2.261.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7854523" target="_blank">7854523</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8165680">Cerebral infarction immediately after ingestion of hydrogen peroxide solution.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sherman SJ,
|
||
Boyer LV,
|
||
Sibley WA</span><br />
|
||
<span class="medgenPMjournal">Stroke</span>
|
||
1994 May;25(5):1065-7.
|
||
doi: 10.1161/01.str.25.5.1065.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8165680" target="_blank">8165680</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Frontal%20release%20signs%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32444154">Discriminant Performance of Dysexecutive and Frontal Release Signs for Delirium in Patients With High Dementia Prevalence: Implications for Neural Network Impairment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Franco JG,
|
||
Trzepacz PT,
|
||
Velásquez-Tirado JD,
|
||
Ocampo MV,
|
||
Serna PA,
|
||
Giraldo AM,
|
||
López C,
|
||
Zuluaga A,
|
||
Zaraza-Morales D</span><br />
|
||
<span class="medgenPMjournal">J Acad Consult Liaison Psychiatry</span>
|
||
2021 Jan-Feb;62(1):56-69.
|
||
Epub 2020 Apr 13
|
||
doi: 10.1016/j.psym.2020.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32444154" target="_blank">32444154</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26705121">Progressive supranuclear palsy: progression and survival.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arena JE,
|
||
Weigand SD,
|
||
Whitwell JL,
|
||
Hassan A,
|
||
Eggers SD,
|
||
Höglinger GU,
|
||
Litvan I,
|
||
Josephs KA</span><br />
|
||
<span class="medgenPMjournal">J Neurol</span>
|
||
2016 Feb;263(2):380-389.
|
||
Epub 2015 Dec 24
|
||
doi: 10.1007/s00415-015-7990-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26705121" target="_blank">26705121</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25042002">The clinical spectrum of isolated peripheral motor dysfunction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sanderson AB,
|
||
Arnold WD,
|
||
Elsheikh B,
|
||
Kissel JT</span><br />
|
||
<span class="medgenPMjournal">Muscle Nerve</span>
|
||
2015 Mar;51(3):358-62.
|
||
Epub 2015 Jan 9
|
||
doi: 10.1002/mus.24326.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25042002" target="_blank">25042002</a><a href="/pmc/articles/PMC4509785" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22054619">Primitive reflexes associated with delirium: a prospective trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nicolson SE,
|
||
Chabon B,
|
||
Larsen KA,
|
||
Kelly SE,
|
||
Potter AW,
|
||
Stern TA</span><br />
|
||
<span class="medgenPMjournal">Psychosomatics</span>
|
||
2011 Nov-Dec;52(6):507-12.
|
||
doi: 10.1016/j.psym.2011.06.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22054619" target="_blank">22054619</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19996256">Subtle neurological signs predict the severity of subacute cognitive and functional impairments after traumatic brain injury.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wortzel HS,
|
||
Frey KL,
|
||
Anderson CA,
|
||
Arciniegas DB</span><br />
|
||
<span class="medgenPMjournal">J Neuropsychiatry Clin Neurosci</span>
|
||
2009 Fall;21(4):463-6.
|
||
doi: 10.1176/jnp.2009.21.4.463.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19996256" target="_blank">19996256</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Frontal%20release%20signs%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32444154">Discriminant Performance of Dysexecutive and Frontal Release Signs for Delirium in Patients With High Dementia Prevalence: Implications for Neural Network Impairment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Franco JG,
|
||
Trzepacz PT,
|
||
Velásquez-Tirado JD,
|
||
Ocampo MV,
|
||
Serna PA,
|
||
Giraldo AM,
|
||
López C,
|
||
Zuluaga A,
|
||
Zaraza-Morales D</span><br />
|
||
<span class="medgenPMjournal">J Acad Consult Liaison Psychiatry</span>
|
||
2021 Jan-Feb;62(1):56-69.
|
||
Epub 2020 Apr 13
|
||
doi: 10.1016/j.psym.2020.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32444154" target="_blank">32444154</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30901701">Discriminative clinical and neuroimaging features of motor-predominant hereditary diffuse leukoencephalopathy with axonal spheroids and primary progressive multiple sclerosis: A preliminary cross-sectional study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Saitoh BY,
|
||
Yamasaki R,
|
||
Hiwatashi A,
|
||
Matsushita T,
|
||
Hayashi S,
|
||
Mitsunaga Y,
|
||
Maeda Y,
|
||
Isobe N,
|
||
Yoshida K,
|
||
Ikeda SI,
|
||
Kira JI</span><br />
|
||
<span class="medgenPMjournal">Mult Scler Relat Disord</span>
|
||
2019 Jun;31:22-31.
|
||
Epub 2019 Mar 12
|
||
doi: 10.1016/j.msard.2019.03.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30901701" target="_blank">30901701</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26705121">Progressive supranuclear palsy: progression and survival.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arena JE,
|
||
Weigand SD,
|
||
Whitwell JL,
|
||
Hassan A,
|
||
Eggers SD,
|
||
Höglinger GU,
|
||
Litvan I,
|
||
Josephs KA</span><br />
|
||
<span class="medgenPMjournal">J Neurol</span>
|
||
2016 Feb;263(2):380-389.
|
||
Epub 2015 Dec 24
|
||
doi: 10.1007/s00415-015-7990-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26705121" target="_blank">26705121</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19996256">Subtle neurological signs predict the severity of subacute cognitive and functional impairments after traumatic brain injury.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wortzel HS,
|
||
Frey KL,
|
||
Anderson CA,
|
||
Arciniegas DB</span><br />
|
||
<span class="medgenPMjournal">J Neuropsychiatry Clin Neurosci</span>
|
||
2009 Fall;21(4):463-6.
|
||
doi: 10.1176/jnp.2009.21.4.463.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19996256" target="_blank">19996256</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17666495">Frontal release signs and cognition in people with schizophrenia, their siblings and healthy controls.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hyde TM,
|
||
Goldberg TE,
|
||
Egan MF,
|
||
Lener MC,
|
||
Weinberger DR</span><br />
|
||
<span class="medgenPMjournal">Br J Psychiatry</span>
|
||
2007 Aug;191:120-5.
|
||
doi: 10.1192/bjp.bp.106.026773.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17666495" target="_blank">17666495</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Frontal%20release%20signs%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (21)</a></div></div>
|
||
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|
||
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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