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<!--
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UID=1864053
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ConceptID=C5937450
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Central giant cell lesion of the jaw</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1864053</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5937450</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:6000715">HP:6000715</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">A benign proliferative and asymptomatic intraosseous lesion of the jaw formed by fibrous tissue that contains multiple focus of hemorrhage and an aggregation of multinucleated giant cells. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Central giant cell lesion of the jaw</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867418" ref="tree=MeSH" title="MedGen record for Abnormality of the skeletal system">Abnormality of the skeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/868760" ref="tree=MeSH" title="MedGen record for Abnormal skeletal morphology">Abnormal skeletal morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892434" ref="tree=MeSH" title="MedGen record for Abnormal axial skeleton morphology">Abnormal axial skeleton morphology</a></span><ul><li><span class="TLline"><a href="/medgen/488801" ref="tree=MeSH" title="MedGen record for Abnormal skull morphology">Abnormal skull morphology</a></span><ul><li><span class="TLline"><a href="/medgen/746145" ref="tree=MeSH" title="MedGen record for Abnormal facial skeleton morphology">Abnormal facial skeleton morphology</a></span><ul><li><span class="TLline"><a href="/medgen/905760" ref="tree=MeSH" title="MedGen record for Abnormal jaw morphology">Abnormal jaw morphology</a></span><ul><li><span class="matched_ds">Central giant cell lesion of the jaw</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_40219"><div><strong>Fibrous dysplasia of jaw</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>40219</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0008029</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cherubism is a childhood-onset, autoinflammatory bone disease characterized by bilateral and symmetric proliferative fibroosseous lesions limited to the mandible and maxilla. The enlargement is usually symmetric in nature. The phenotype ranges from no clinical manifestations to severe mandibular and maxillary overgrowth with respiratory, vision, speech, and swallowing problems. In most affected persons, teeth are displaced, unerupted, unformed, or absent, or may appear to be floating in cystlike spaces; malocclusion, premature exfoliation of deciduous teeth, and root resorption have also been reported. The course and duration of the active process of bone destruction varies between affected individuals; the onset is usually in early childhood, and typically new lesions can occur until puberty. Regression of the lesions occurs as they become filled with bone and remodel during the second and third decade of life. By age 30 years, the facial abnormalities associated with cherubism are not usually recognizable and residual deformity of the jaws is rare. Typically, cherubism is an isolated benign condition; the affected person has normal intellectual skills and is without other physical anomalies.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/40219">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_40219" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fibrous dysplasia of jaw</a></div></div>
|
||
</div>
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||
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||
<div class="portlet mgSection" id="ID_105">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/19464656">Central giant cell lesion of the jaw: nonsurgical treatment with calcitonin nasal spray.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Allon DM,
|
||
Anavi Y,
|
||
Calderon S</span><br />
|
||
<span class="medgenPMjournal">Oral Surg Oral Med Oral Pathol Oral Radiol Endod</span>
|
||
2009 Jun;107(6):811-8.
|
||
doi: 10.1016/j.tripleo.2009.02.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19464656" target="_blank">19464656</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22central%20giant%20cell%20lesion%20of%20the%20jaw%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35088118">Clinical and Radiologic Response of Central Giant Cell Granuloma to Denosumab: A 6-Year Prospective Observational Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rhou YJJ,
|
||
Wang CJ,
|
||
Nguyen M,
|
||
Vanderniet JA,
|
||
Munns CF,
|
||
Coleman H,
|
||
Kim J,
|
||
Holmes-Walker DJ,
|
||
Lim L,
|
||
Girgis CM</span><br />
|
||
<span class="medgenPMjournal">Calcif Tissue Int</span>
|
||
2022 Apr;110(4):464-474.
|
||
Epub 2022 Jan 28
|
||
doi: 10.1007/s00223-021-00935-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35088118" target="_blank">35088118</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32030708">Giant Cell Lesions of the Jaws:A Review and Comparative Histopathological Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akinyamoju AO,
|
||
Soyele OO,
|
||
Saiki TE,
|
||
Adesina OM</span><br />
|
||
<span class="medgenPMjournal">West Afr J Med</span>
|
||
2020 Jan-Mar;37(1):26-31.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32030708" target="_blank">32030708</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30825099">Central giant cell granulomas of the jaws: retrospective radiographic analysis of 13 patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Etoz M,
|
||
Asantogrol F,
|
||
Akyol R</span><br />
|
||
<span class="medgenPMjournal">Oral Radiol</span>
|
||
2020 Jan;36(1):60-68.
|
||
Epub 2019 Mar 1
|
||
doi: 10.1007/s11282-019-00380-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30825099" target="_blank">30825099</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27046538">The root of the problem: Occurrence of typical and atypical periapical pathoses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sullivan M,
|
||
Gallagher G,
|
||
Noonan V</span><br />
|
||
<span class="medgenPMjournal">J Am Dent Assoc</span>
|
||
2016 Aug;147(8):646-9.
|
||
Epub 2016 Apr 1
|
||
doi: 10.1016/j.adaj.2016.02.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27046538" target="_blank">27046538</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19821413">Interventions for central giant cell granuloma (CGCG) of the jaws.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Suárez-Roa Mde L,
|
||
Reveiz L,
|
||
Ruíz-Godoy Rivera LM,
|
||
Asbun-Bojalil J,
|
||
Dávila-Serapio JE,
|
||
Menjívar-Rubio AH,
|
||
Meneses-García A</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2009 Oct 7;(4):CD007404.
|
||
doi: 10.1002/14651858.CD007404.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19821413" target="_blank">19821413</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20giant%20cell%20lesion%20of%20the%20jaw%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (72)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32030708">Giant Cell Lesions of the Jaws:A Review and Comparative Histopathological Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akinyamoju AO,
|
||
Soyele OO,
|
||
Saiki TE,
|
||
Adesina OM</span><br />
|
||
<span class="medgenPMjournal">West Afr J Med</span>
|
||
2020 Jan-Mar;37(1):26-31.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32030708" target="_blank">32030708</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30900672">Central giant cell granuloma - A case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Balaji P,
|
||
Balaji SM</span><br />
|
||
<span class="medgenPMjournal">Indian J Dent Res</span>
|
||
2019 Jan-Feb;30(1):130-132.
|
||
doi: 10.4103/ijdr.IJDR_61_19.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30900672" target="_blank">30900672</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29157551">Fibro-Osseous and Other Lesions of Bone in the Jaws.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ahmad M,
|
||
Gaalaas L</span><br />
|
||
<span class="medgenPMjournal">Radiol Clin North Am</span>
|
||
2018 Jan;56(1):91-104.
|
||
Epub 2017 Oct 19
|
||
doi: 10.1016/j.rcl.2017.08.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29157551" target="_blank">29157551</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19041522">Hybrid central giant cell granuloma and central odontogenic fibroma-like lesion of the mandible.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Lima Mde D,
|
||
de Aquino Xavier FC,
|
||
Vanti LA,
|
||
de Lima PS,
|
||
de Sousa SC</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Head Neck Surg</span>
|
||
2008 Dec;139(6):867-8.
|
||
doi: 10.1016/j.otohns.2008.08.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19041522" target="_blank">19041522</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10587271">Odontogenic fibroma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dunlap CL</span><br />
|
||
<span class="medgenPMjournal">Semin Diagn Pathol</span>
|
||
1999 Nov;16(4):293-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10587271" target="_blank">10587271</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20giant%20cell%20lesion%20of%20the%20jaw%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (118)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38539018">Denosumab as treatment of central giant cell granuloma of the jaws. a scoping review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Latorre CG,
|
||
Atalah CN,
|
||
Marshall Baburizza M</span><br />
|
||
<span class="medgenPMjournal">Oral Maxillofac Surg</span>
|
||
2024 Sep;28(3):1029-1045.
|
||
Epub 2024 Mar 28
|
||
doi: 10.1007/s10006-024-01245-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38539018" target="_blank">38539018</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35088118">Clinical and Radiologic Response of Central Giant Cell Granuloma to Denosumab: A 6-Year Prospective Observational Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rhou YJJ,
|
||
Wang CJ,
|
||
Nguyen M,
|
||
Vanderniet JA,
|
||
Munns CF,
|
||
Coleman H,
|
||
Kim J,
|
||
Holmes-Walker DJ,
|
||
Lim L,
|
||
Girgis CM</span><br />
|
||
<span class="medgenPMjournal">Calcif Tissue Int</span>
|
||
2022 Apr;110(4):464-474.
|
||
Epub 2022 Jan 28
|
||
doi: 10.1007/s00223-021-00935-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35088118" target="_blank">35088118</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34411774">Central giant cell granuloma of the head & neck: A case report and systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Richardson J,
|
||
Stanbouly D,
|
||
Litman E,
|
||
Lee KC,
|
||
Philipone E</span><br />
|
||
<span class="medgenPMjournal">J Stomatol Oral Maxillofac Surg</span>
|
||
2022 Sep;123(4):e161-e168.
|
||
Epub 2021 Aug 17
|
||
doi: 10.1016/j.jormas.2021.08.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34411774" target="_blank">34411774</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19821413">Interventions for central giant cell granuloma (CGCG) of the jaws.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Suárez-Roa Mde L,
|
||
Reveiz L,
|
||
Ruíz-Godoy Rivera LM,
|
||
Asbun-Bojalil J,
|
||
Dávila-Serapio JE,
|
||
Menjívar-Rubio AH,
|
||
Meneses-García A</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2009 Oct 7;(4):CD007404.
|
||
doi: 10.1002/14651858.CD007404.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19821413" target="_blank">19821413</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17703964">Central giant cell granuloma of the jaw: a review of the literature with emphasis on therapy options.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Lange J,
|
||
van den Akker HP,
|
||
van den Berg H</span><br />
|
||
<span class="medgenPMjournal">Oral Surg Oral Med Oral Pathol Oral Radiol Endod</span>
|
||
2007 Nov;104(5):603-15.
|
||
Epub 2007 Aug 20
|
||
doi: 10.1016/j.tripleo.2007.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17703964" target="_blank">17703964</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20giant%20cell%20lesion%20of%20the%20jaw%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (36)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35088118">Clinical and Radiologic Response of Central Giant Cell Granuloma to Denosumab: A 6-Year Prospective Observational Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rhou YJJ,
|
||
Wang CJ,
|
||
Nguyen M,
|
||
Vanderniet JA,
|
||
Munns CF,
|
||
Coleman H,
|
||
Kim J,
|
||
Holmes-Walker DJ,
|
||
Lim L,
|
||
Girgis CM</span><br />
|
||
<span class="medgenPMjournal">Calcif Tissue Int</span>
|
||
2022 Apr;110(4):464-474.
|
||
Epub 2022 Jan 28
|
||
doi: 10.1007/s00223-021-00935-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35088118" target="_blank">35088118</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27883876">Comprehensive Genomic Profiling of Central Giant Cell Lesions Identifies Clinically Relevant Genomic Alterations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bezak B,
|
||
Lehrke H,
|
||
Elvin J,
|
||
Gay L,
|
||
Schembri-Wismayer D,
|
||
Viozzi C</span><br />
|
||
<span class="medgenPMjournal">J Oral Maxillofac Surg</span>
|
||
2017 May;75(5):955-961.
|
||
Epub 2016 Nov 1
|
||
doi: 10.1016/j.joms.2016.10.027.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27883876" target="_blank">27883876</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11904346">Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Regezi JA</span><br />
|
||
<span class="medgenPMjournal">Mod Pathol</span>
|
||
2002 Mar;15(3):331-41.
|
||
doi: 10.1038/modpathol.3880527.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11904346" target="_blank">11904346</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10587271">Odontogenic fibroma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dunlap CL</span><br />
|
||
<span class="medgenPMjournal">Semin Diagn Pathol</span>
|
||
1999 Nov;16(4):293-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10587271" target="_blank">10587271</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7553374">Peripheral giant cell granuloma: a clinical study of 77 cases from 62 patients, and literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mighell AJ,
|
||
Robinson PA,
|
||
Hume WJ</span><br />
|
||
<span class="medgenPMjournal">Oral Dis</span>
|
||
1995 Mar;1(1):12-9.
|
||
doi: 10.1111/j.1601-0825.1995.tb00151.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7553374" target="_blank">7553374</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20giant%20cell%20lesion%20of%20the%20jaw%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (51)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38539018">Denosumab as treatment of central giant cell granuloma of the jaws. a scoping review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Latorre CG,
|
||
Atalah CN,
|
||
Marshall Baburizza M</span><br />
|
||
<span class="medgenPMjournal">Oral Maxillofac Surg</span>
|
||
2024 Sep;28(3):1029-1045.
|
||
Epub 2024 Mar 28
|
||
doi: 10.1007/s10006-024-01245-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38539018" target="_blank">38539018</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38453790">Central giant cell granuloma of the jaws-long-term clinical and radiological outcomes of surgical and pharmacological management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Capucha T,
|
||
Krasovsky A,
|
||
Abdalla-Aslan R,
|
||
Ginini JG,
|
||
Noy D,
|
||
Emodi O,
|
||
Rachmiel A,
|
||
Shilo D</span><br />
|
||
<span class="medgenPMjournal">Clin Oral Investig</span>
|
||
2024 Mar 7;28(3):200.
|
||
doi: 10.1007/s00784-024-05585-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38453790" target="_blank">38453790</a><a href="/pmc/articles/PMC10920455" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35088118">Clinical and Radiologic Response of Central Giant Cell Granuloma to Denosumab: A 6-Year Prospective Observational Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rhou YJJ,
|
||
Wang CJ,
|
||
Nguyen M,
|
||
Vanderniet JA,
|
||
Munns CF,
|
||
Coleman H,
|
||
Kim J,
|
||
Holmes-Walker DJ,
|
||
Lim L,
|
||
Girgis CM</span><br />
|
||
<span class="medgenPMjournal">Calcif Tissue Int</span>
|
||
2022 Apr;110(4):464-474.
|
||
Epub 2022 Jan 28
|
||
doi: 10.1007/s00223-021-00935-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35088118" target="_blank">35088118</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35048460">Central giant cell granulomas of the jaws stromal cells harbour mutations and have osteogenic differentiation capacity, in vivo and in vitro.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miguita L,
|
||
de Souza JC,
|
||
Bastos VC,
|
||
Pereira NB,
|
||
de Freitas RAB,
|
||
Guimarães LM,
|
||
de Avelar GF,
|
||
Andrade LO,
|
||
Dutra WO,
|
||
Nunes FD,
|
||
Castro WH,
|
||
de Lacerda JCT,
|
||
Reis AMS,
|
||
Bernardes VF,
|
||
Diniz MG,
|
||
Gomez RS,
|
||
Gomes CC</span><br />
|
||
<span class="medgenPMjournal">J Oral Pathol Med</span>
|
||
2022 Feb;51(2):206-216.
|
||
Epub 2022 Feb 6
|
||
doi: 10.1111/jop.13274.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35048460" target="_blank">35048460</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27883876">Comprehensive Genomic Profiling of Central Giant Cell Lesions Identifies Clinically Relevant Genomic Alterations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bezak B,
|
||
Lehrke H,
|
||
Elvin J,
|
||
Gay L,
|
||
Schembri-Wismayer D,
|
||
Viozzi C</span><br />
|
||
<span class="medgenPMjournal">J Oral Maxillofac Surg</span>
|
||
2017 May;75(5):955-961.
|
||
Epub 2016 Nov 1
|
||
doi: 10.1016/j.joms.2016.10.027.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27883876" target="_blank">27883876</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20giant%20cell%20lesion%20of%20the%20jaw%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (68)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/34411774">Central giant cell granuloma of the head & neck: A case report and systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Richardson J,
|
||
Stanbouly D,
|
||
Litman E,
|
||
Lee KC,
|
||
Philipone E</span><br />
|
||
<span class="medgenPMjournal">J Stomatol Oral Maxillofac Surg</span>
|
||
2022 Sep;123(4):e161-e168.
|
||
Epub 2021 Aug 17
|
||
doi: 10.1016/j.jormas.2021.08.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34411774" target="_blank">34411774</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32730731">A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alsufyani NA,
|
||
Aldosary RM,
|
||
Alrasheed RS,
|
||
Alsaif RF</span><br />
|
||
<span class="medgenPMjournal">Acta Odontol Scand</span>
|
||
2021 Mar;79(2):124-131.
|
||
Epub 2020 Jul 30
|
||
doi: 10.1080/00016357.2020.1797160.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32730731" target="_blank">32730731</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32192952">Brown tumors of the oral cavity: presentation of 4 new cases and a systematic literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lajolo C,
|
||
Patini R,
|
||
Limongelli L,
|
||
Favia G,
|
||
Tempesta A,
|
||
Contaldo M,
|
||
De Corso E,
|
||
Giuliani M</span><br />
|
||
<span class="medgenPMjournal">Oral Surg Oral Med Oral Pathol Oral Radiol</span>
|
||
2020 Jun;129(6):575-584.e4.
|
||
Epub 2020 Mar 17
|
||
doi: 10.1016/j.oooo.2020.02.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32192952" target="_blank">32192952</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19821413">Interventions for central giant cell granuloma (CGCG) of the jaws.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Suárez-Roa Mde L,
|
||
Reveiz L,
|
||
Ruíz-Godoy Rivera LM,
|
||
Asbun-Bojalil J,
|
||
Dávila-Serapio JE,
|
||
Menjívar-Rubio AH,
|
||
Meneses-García A</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2009 Oct 7;(4):CD007404.
|
||
doi: 10.1002/14651858.CD007404.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19821413" target="_blank">19821413</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20giant%20cell%20lesion%20of%20the%20jaw%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div></div>
|
||
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|
||
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22central%20giant%20cell%20lesion%20of%20the%20jaw%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Central%20giant%20cell%20lesion%20of%20the%20jaw%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d367bdcde49f3df7632e44">Central giant cell lesion of the jaw</a>
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