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<!--
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||
UID=1648424
|
||
ConceptID=C4721411
|
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Osteolysis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648424</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4721411</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Osteolyses</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Osteolysis (203522001); Osteolysis (30425001)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002797">HP:0002797</a></td></tr>
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||
<div class="portlet_content ln">Osteolysis refers to the destruction of bone through bone resorption with removal or loss of calcium. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C4721411[DISCUI]&test_type=Clinical" ref="ncbi_uid=1648424">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Osteolysis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/867418" ref="tree=MeSH" title="MedGen record for Abnormality of the skeletal system">Abnormality of the skeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/868760" ref="tree=MeSH" title="MedGen record for Abnormal skeletal morphology">Abnormal skeletal morphology</a></span><ul><li><span class="TLline"><a href="/medgen/871157" ref="tree=MeSH" title="MedGen record for Abnormal bone structure">Abnormal bone structure</a></span><ul><li><span class="matched_ds">Osteolysis</span><ul><li><span class="TLline"><a href="/medgen/183017" ref="tree=MeSH" title="MedGen record for Acroosteolysis">Acroosteolysis</a></span><ul><li><span class="TLline"><a href="/medgen/182961" ref="tree=MeSH" title="MedGen record for Hajdu-Cheney syndrome">Hajdu-Cheney syndrome</a></span></li><li><span class="TLline"><a href="/medgen/866560" ref="tree=MeSH" title="MedGen record for Osteolytic defect of thumb phalanx">Osteolytic defect of thumb phalanx</a></span></li><li><span class="TLline"><a href="/medgen/867085" ref="tree=MeSH" title="MedGen record for Osteolytic defects of the phalanges of the 2nd finger">Osteolytic defects of the phalanges of the 2nd finger</a></span></li><li><span class="TLline"><a href="/medgen/867114" ref="tree=MeSH" title="MedGen record for Osteolytic defects of the phalanges of the 3rd finger">Osteolytic defects of the phalanges of the 3rd finger</a></span></li><li><span class="TLline"><a href="/medgen/892409" ref="tree=MeSH" title="MedGen record for Osteolytic defects of the phalanges of the 4th finger">Osteolytic defects of the phalanges of the 4th finger</a></span></li><li><span class="TLline"><a href="/medgen/867314" ref="tree=MeSH" title="MedGen record for Osteolytic defects of the phalanges of the 5th finger">Osteolytic defects of the phalanges of the 5th finger</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/45247" ref="tree=MeSH" title="MedGen record for Disappearing bone disease">Disappearing bone disease</a></span></li><li><span class="TLline"><a href="/medgen/462800" ref="tree=MeSH" title="MedGen record for Mandibular osteolysis">Mandibular osteolysis</a></span></li><li><span class="TLline"><a href="/medgen/324869" ref="tree=MeSH" title="MedGen record for Progressive clavicular acroosteolysis">Progressive clavicular acroosteolysis</a></span></li><li><span class="TLline"><a href="/medgen/462799" ref="tree=MeSH" title="MedGen record for Rib osteolysis">Rib osteolysis</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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||
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||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_46123"><div><strong>Hutchinson-Gilford syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>46123</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0033300</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hutchinson-Gilford progeria syndrome (HGPS) is characterized by clinical features that typically develop in childhood and resemble some features of accelerated aging. Children with HGPS usually appear normal at birth. Profound failure to thrive occurs during the first year. Characteristic facial features include head that is disproportionately large for the face, narrow nasal ridge, narrow nasal tip, thin vermilion of the upper and lower lips, small mouth, and retro- and micrognathia. Common features include loss of subcutaneous fat, delayed eruption and loss of primary teeth, abnormal skin with small outpouchings over the abdomen and upper thighs, alopecia, nail dystrophy, coxa valga, and progressive joint contractures. Later findings include low-frequency conductive hearing loss, dental crowding, and partial lack of secondary tooth eruption. Motor and mental development is normal. Death occurs as a result of complications of severe atherosclerosis, either cardiac disease (myocardial infarction or heart failure) or cerebrovascular disease (stroke), generally between ages six and 20 years (average 14.5 years) without lonafarnib treatment or cardiac surgery intervention. Average life span is extended to approximately 17-19.5 years with lonafarnib therapy.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/46123">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_96593"><div><strong>Familial expansile osteolysis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>96593</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432292</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial expansile osteolysis is an autosomal dominant bone dysplasia characterized by increased bone remodeling with osteolytic lesions mainly affecting the appendicular skeleton. There is medullary and cortical expansion of the bone without sclerosis, leading to painful and disabling deformities and tendency to pathologic fracture. Clinical features include onset of conductive hearing loss in childhood, premature loss of teeth, and variably increased serum alkaline phosphatase (summary by Palenzuela et al., 2002 and Elahi et al., 2007).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/96593">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_339991"><div><strong>Paget disease of bone 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>339991</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1853473</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/339991">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_411230"><div><strong>Sterile multifocal osteomyelitis with periostitis and pustulosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>411230</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2748507</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Chronic recurrent multifocal osteomyelitis-2 with periostitis and pustulosis (CRMO2) is an autosomal recessive multisystemic autoinflammatory disorder characterized by onset of symptoms in early infancy. Affected individuals present with joint swelling and pain, pustular rash, oral mucosal lesions, and fetal distress. The disorder progresses in severity to generalized severe pustulosis or ichthyosiform lesions and diffuse bone lesions. Radiographic studies show widening of the anterior rib ends, periosteal elevation along multiple long bones, multifocal osteolytic lesions, heterotopic ossification, and metaphyseal erosions of the long bones. Laboratory studies show elevation of inflammatory markers. The disorder results from unopposed activation of the IL1 inflammatory signaling pathway. Treatment with the interleukin-1 receptor antagonist anakinra may result in clinical improvement (Aksentijevich et al., 2009). For a discussion of genetic heterogeneity of CRMO, see 609628.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/411230">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462796"><div><strong>Nestor-Guillermo progeria syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462796</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151446</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Nestor-Guillermo progeria syndrome (NGPS) is an autosomal recessive disorder characterized by lipoatrophy, osteoporosis, and very severe osteolysis. Patients have no cardiovascular impairment, diabetes mellitus, or hypertriglyceridemia, but suffer profound skeletal abnormalities that affect their quality of life. Onset is after 2 years of age, and lifespan is relatively long (summary by Cabanillas et al., 2011).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462796">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_899166"><div><strong>Paget disease of bone 2, early-onset</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>899166</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4085251</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Paget disease (PDB) is a metabolic bone disease characterized by focal abnormalities of increased bone turnover affecting one or more sites throughout the skeleton, primarily the axial skeleton. Bone lesions in this disorder show evidence of increased osteoclastic bone resorption and disorganized bone structure. See reviews by Ralston et al. (2008) and Ralston and Albagha (2014). For a discussion of genetic heterogeneity of Paget disease of bone, see 167250.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/899166">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_895927"><div><strong>Paget disease of bone 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>895927</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4085252</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Paget disease (PDB) is a metabolic bone disease characterized by focal abnormalities of increased bone turnover affecting one or more sites throughout the skeleton, primarily the axial skeleton. Bone lesions in this disorder show evidence of increased osteoclastic bone resorption and disorganized bone structure. See reviews by Ralston et al. (2008) and Ralston and Albagha (2014). Genetic Heterogeneity of Paget Disease of Bone Also see PDB2 (602080), caused by mutation in the TNFRSF11A gene (603499) on chromosome 18q21; PDB4 (606263), mapped to chromosome 5q31; PDB5 (239000), caused by mutation in the TNFRSF11B gene (602643) on chromosome 8q24; and PDB6 (616833), caused by mutation in the ZNF687 gene (610568) on chromosome 1q21. Suggestive linkage of a form of PDB to chromosome 6p (PDB1) was reported by Fotino et al. (1977); however, further studies did not confirm linkage to this site (Moore and Hoffman, 1988; Nance et al., 2000; Good et al., 2001).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/895927">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1805033"><div><strong>Hyaline fibromatosis syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1805033</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5574677</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyaline fibromatosis syndrome (HFS) is characterized by hyaline deposits in the papillary dermis and other tissues. It can present at birth or in infancy with severe pain with movement, progressive joint contractures, and often with severe motor disability, thickened skin, and hyperpigmented macules/patches over bony prominences of the joints. Gingival hypertrophy, skin nodules, pearly papules of the face and neck, and perianal masses are common. Complications of protein-losing enteropathy and failure to thrive can be life threatening. Cognitive development is normal. Many children with the severe form (previously called infantile systemic hyalinosis) have a significant risk of morbidity or mortality in early childhood; some with a milder phenotype (previously called juvenile hyaline fibromatosis) survive into adulthood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1805033">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1861084"><div><strong>Cutaneous porphyria</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1861084</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5886774</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Congenital erythropoietic porphyria (CEP) is characterized in most individuals by severe cutaneous photosensitivity with blistering and increased friability of the skin over light-exposed areas. Onset in most affected individuals occurs at birth or early infancy. The first manifestation is often pink-to-dark red discoloration of the urine. Hemolytic anemia is common and can range from mild to severe, with some affected individuals requiring chronic blood transfusions. Porphyrin deposition may lead to corneal ulcers and scarring, reddish-brown discoloration of the teeth (erythrodontia), and bone loss and/or expansion of the bone marrow. The phenotypic spectrum, however, is broad and ranges from nonimmune hydrops fetalis in utero to late-onset disease with only mild cutaneous manifestations in adulthood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1861084">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1861084" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cutaneous porphyria</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_96593" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial expansile osteolysis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_46123" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hutchinson-Gilford syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1805033" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyaline fibromatosis syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462796" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nestor-Guillermo progeria syndrome</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (9)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_899166" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Paget disease of bone 2, early-onset</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_895927" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Paget disease of bone 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_339991" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Paget disease of bone 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_411230" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Sterile multifocal osteomyelitis with periostitis and pustulosis</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35969258">Acro-osteolysis: imaging, differential diagnosis, and disposition review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bailey CT,
|
||
Zelaya R,
|
||
Kayder OO,
|
||
Cecava ND</span><br />
|
||
<span class="medgenPMjournal">Skeletal Radiol</span>
|
||
2023 Jan;52(1):9-22.
|
||
Epub 2022 Aug 15
|
||
doi: 10.1007/s00256-022-04145-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35969258" target="_blank">35969258</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18685424">Cathepsin K inhibitors as treatment of bone metastasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Le Gall C,
|
||
Bonnelye E,
|
||
Clézardin P</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Support Palliat Care</span>
|
||
2008 Sep;2(3):218-22.
|
||
doi: 10.1097/SPC.0b013e32830baea9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18685424" target="_blank">18685424</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9571433">Osteolysis: surgical treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rubash HE,
|
||
Sinha RK,
|
||
Maloney WJ,
|
||
Paprosky WG</span><br />
|
||
<span class="medgenPMjournal">Instr Course Lect</span>
|
||
1998;47:321-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9571433" target="_blank">9571433</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22osteolysis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (162)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36259858">Werner syndrome associated with acroosteolysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khalid T,
|
||
Inam F,
|
||
Iqbal MA</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2022 Aug 15;28(4)
|
||
doi: 10.5070/D328458520.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36259858" target="_blank">36259858</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27796661">Acro-osteolysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Botou A,
|
||
Bangeas A,
|
||
Alexiou I,
|
||
Sakkas LI</span><br />
|
||
<span class="medgenPMjournal">Clin Rheumatol</span>
|
||
2017 Jan;36(1):9-14.
|
||
Epub 2016 Oct 29
|
||
doi: 10.1007/s10067-016-3459-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27796661" target="_blank">27796661</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18365834">Alternative macrophage activation in periprosthetic osteolysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Purdue PE</span><br />
|
||
<span class="medgenPMjournal">Autoimmunity</span>
|
||
2008 Apr;41(3):212-7.
|
||
doi: 10.1080/08916930701694626.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18365834" target="_blank">18365834</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11794271">Winchester syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Matthiesen G,
|
||
Pedersen VF,
|
||
Helin P,
|
||
Jacobsen GK,
|
||
Nielsen NS</span><br />
|
||
<span class="medgenPMjournal">Int Orthop</span>
|
||
2001;25(5):331-3.
|
||
doi: 10.1007/s002640100276.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11794271" target="_blank">11794271</a><a href="/pmc/articles/PMC3620798" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8203959">Hajdu-Cheney syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Reilly MA,
|
||
Shaw DG</span><br />
|
||
<span class="medgenPMjournal">Ann Rheum Dis</span>
|
||
1994 Apr;53(4):276-9.
|
||
doi: 10.1136/ard.53.4.276.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8203959" target="_blank">8203959</a><a href="/pmc/articles/PMC1005309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteolysis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3668)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37847009">Osteolysis in a Patient with Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Keret S,
|
||
Shouval A,
|
||
Lurie M,
|
||
Slobodin G</span><br />
|
||
<span class="medgenPMjournal">Isr Med Assoc J</span>
|
||
2023 Oct;25(10):716.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37847009" target="_blank">37847009</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31864531">Complex Lymphatic Anomalies and Therapeutic Options.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chaudry G</span><br />
|
||
<span class="medgenPMjournal">Tech Vasc Interv Radiol</span>
|
||
2019 Dec;22(4):100632.
|
||
Epub 2019 Sep 21
|
||
doi: 10.1016/j.tvir.2019.100632.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31864531" target="_blank">31864531</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31452506">Gorham-Stout Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schneider KN,
|
||
Gosheger G,
|
||
Andreou D</span><br />
|
||
<span class="medgenPMjournal">Dtsch Arztebl Int</span>
|
||
2019 Jul 22;116(29-30):507.
|
||
doi: 10.3238/arztebl.2019.0507a.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31452506" target="_blank">31452506</a><a href="/pmc/articles/PMC6726853" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22056097">Lytic lesion.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Punja M,
|
||
McWey RP,
|
||
Heller M</span><br />
|
||
<span class="medgenPMjournal">J Emerg Med</span>
|
||
2013 Jan;44(1):179-80.
|
||
Epub 2011 Nov 4
|
||
doi: 10.1016/j.jemermed.2011.06.058.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22056097" target="_blank">22056097</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8203959">Hajdu-Cheney syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Reilly MA,
|
||
Shaw DG</span><br />
|
||
<span class="medgenPMjournal">Ann Rheum Dis</span>
|
||
1994 Apr;53(4):276-9.
|
||
doi: 10.1136/ard.53.4.276.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8203959" target="_blank">8203959</a><a href="/pmc/articles/PMC1005309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteolysis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2468)</a></div><h3 class="subhead">Therapy</h3>
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<div class="nl"><a target="_blank" href="/pubmed/29986084">Gorham-Stout syndrome.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Liu SZ,
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Zhou X,
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Song A,
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Liu Y</span><br />
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2018 Dec 1;111(12):911-912.
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<div class="nl"><a target="_blank" href="/pubmed/28806267">Evaluation and Treatment of Femoral Osteolysis Following Total Hip Arthroplasty.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gittings DJ,
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Dattilo JR,
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<div class="nl"><a target="_blank" href="/pubmed/28502348">Osteolysis in Total Ankle Replacement: How Does It Work?</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Espinosa N,
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2017 Jun;22(2):267-275.
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<span class="bold">PMID: </span><a href="/pubmed/28502348" target="_blank">28502348</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/26043046">Durability of highly cross-linked polyethylene in total hip and total knee arthroplasty.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Dion NT,
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Bragdon C,
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<span class="bold">PMID: </span><a href="/pubmed/26043046" target="_blank">26043046</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25539400">Wear and loosening in total knee arthroplasty: a quick review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Fraser JF,
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<span class="bold">PMID: </span><a href="/pubmed/25539400" target="_blank">25539400</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteolysis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3358)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/34538473">Cervical Total Disc Replacement: Complications and Complication Avoidance.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Price RL,
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Coric D,
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<div class="nl"><a target="_blank" href="/pubmed/33573813">Long-Term Outcome on the Mal-Seating of Ceramic-on-Ceramic Articulation in Total Hip Arthroplasty.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Chung KY,
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Cheung KW,
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Fan CH,
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Poon WC,
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Chiu KH,
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Ho KK</span><br />
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<span class="medgenPMjournal">J Arthroplasty</span>
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2021 Jun;36(6):2100-2104.
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Epub 2021 Jan 18
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doi: 10.1016/j.arth.2021.01.024.
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<span class="bold">PMID: </span><a href="/pubmed/33573813" target="_blank">33573813</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30124603">Calcinosis in scleroderma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Valenzuela A,
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Song P,
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Chung L</span><br />
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doi: 10.1097/BOR.0000000000000539.
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<span class="bold">PMID: </span><a href="/pubmed/30124603" target="_blank">30124603</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/24968562">Gorham's disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Jayaprakash B,
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<div class="nl"><a target="_blank" href="/pubmed/8203959">Hajdu-Cheney syndrome.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">O'Reilly MA,
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<span class="bold">PMID: </span><a href="/pubmed/8203959" target="_blank">8203959</a><a href="/pmc/articles/PMC1005309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteolysis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2595)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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||
<div class="nl"><a target="_blank" href="/pubmed/37727991">A precision-based exercise program for patients with multiple myeloma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Dapunt U,
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Ehret P,
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Paratte JL,
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Kuehl RM,
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Wiskemann J,
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Jäger D,
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Müller-Tidow C,
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Raab MS,
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Goldschmidt H</span><br />
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<span class="medgenPMjournal">Eur J Haematol</span>
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2023 Dec;111(6):930-937.
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Epub 2023 Sep 20
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doi: 10.1111/ejh.14106.
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<span class="bold">PMID: </span><a href="/pubmed/37727991" target="_blank">37727991</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31864531">Complex Lymphatic Anomalies and Therapeutic Options.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Chaudry G</span><br />
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2019 Dec;22(4):100632.
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<span class="bold">PMID: </span><a href="/pubmed/31864531" target="_blank">31864531</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/26471860">Peripheral joint involvement in psoriatic arthritis patients.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Acosta Felquer ML,
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FitzGerald O</span><br />
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<span class="medgenPMjournal">Clin Exp Rheumatol</span>
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2015 Sep-Oct;33(5 Suppl 93):S26-30.
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Epub 2015 Oct 15
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<div class="nl"><a target="_blank" href="/pubmed/23996098">Classifications in brief: Paprosky classification of acetabular bone loss.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Telleria JJ,
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Epub 2013 Aug 31
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||
<div class="nl"><a target="_blank" href="/pubmed/21298758">Gorham's disease and diffuse lymphangiomatosis in children and adolescents.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Venkatramani R,
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Ma NS,
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Pitukcheewanont P,
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Malogolowkin MH,
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<span class="bold">PMID: </span><a href="/pubmed/21298758" target="_blank">21298758</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteolysis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2770)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/30898430">Gorham-Stout disease with involvement of the jaws: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chrcanovic BR,
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||
Gomez RS</span><br />
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<span class="medgenPMjournal">Int J Oral Maxillofac Surg</span>
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2019 Aug;48(8):1015-1021.
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Epub 2019 Mar 18
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doi: 10.1016/j.ijom.2019.03.002.
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||
<span class="bold">PMID: </span><a href="/pubmed/30898430" target="_blank">30898430</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30422837">Failed Total Hip Arthroplasty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bou Monsef J,
|
||
Parekh A,
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Osmani F,
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Gonzalez M</span><br />
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<span class="medgenPMjournal">JBJS Rev</span>
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2018 Nov;6(11):e3.
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doi: 10.2106/JBJS.RVW.17.00140.
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<span class="bold">PMID: </span><a href="/pubmed/30422837" target="_blank">30422837</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24963082">Total wrist arthroplasty: a systematic review of the evidence from the last 5 years.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Yeoh D,
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Tourret L</span><br />
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<span class="medgenPMjournal">J Hand Surg Eur Vol</span>
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2015 Jun;40(5):458-68.
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Epub 2014 Jun 23
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doi: 10.1177/1753193414539796.
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<span class="bold">PMID: </span><a href="/pubmed/24963082" target="_blank">24963082</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/25034883">Total hip arthroplasty after acetabular fracture: incidence of complications, reoperation rates and functional outcomes: evidence today.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Makridis KG,
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Obakponovwe O,
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Bobak P,
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<span class="medgenPMjournal">J Arthroplasty</span>
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||
2014 Oct;29(10):1983-90.
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||
Epub 2014 Jun 12
|
||
doi: 10.1016/j.arth.2014.06.001.
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||
<span class="bold">PMID: </span><a href="/pubmed/25034883" target="_blank">25034883</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17654508">Treatment options in skeletal localizations of hairy cell leukemia: a systematic review on the role of radiation therapy.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Filippi AR,
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Franco P,
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Marinone C,
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Tarella C,
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<span class="medgenPMjournal">Am J Hematol</span>
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2007 Nov;82(11):1017-21.
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<span class="bold">PMID: </span><a href="/pubmed/17654508" target="_blank">17654508</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Osteolysis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (70)</a></div></div>
|
||
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|
||
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|
||
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||
<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C4721411%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (8)</a></li>
|
||
<li><a href="/gtr/tests?term=C4721411%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (8)</a></li>
|
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C4721411%5bDISCUI%5d" target="_blank">See all (8)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Osteolysis" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22osteolysis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Osteolysis%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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