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<meta name="keywords" content="C4703646, eosinophilic esophagitis, eosinophilic infiltration of the esophagus, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Infiltration of numerous eosinophils (usually greater than 15 per high power field) into the squamous epithelium of the esophagus, and layering of eosinophils on the surface layer of the esophagus." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=1637185
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ConceptID=C4703646
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Eosinophilic infiltration of the esophagus</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1637185</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4703646</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Eosinophilic esophagitis</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0410151">HP:0410151</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Infiltration of numerous eosinophils (usually greater than 15 per high power field) into the squamous epithelium of the esophagus, and layering of eosinophils on the surface layer of the esophagus. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Eosinophilic infiltration of the esophagus</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/8970" ref="tree=MeSH" title="MedGen record for Disorder of gastrointestinal tract">Disorder of gastrointestinal tract</a></span><ul><li><span class="TLline"><a href="/medgen/8693" ref="tree=MeSH" title="MedGen record for Esophageal disorder">Esophageal disorder</a></span><ul><li><span class="TLline"><a href="/medgen/4549" ref="tree=MeSH" title="MedGen record for Esophagitis">Esophagitis</a></span><ul><li><span class="matched_ds">Eosinophilic infiltration of the esophagus</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
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||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_382398"><div><strong>Loeys-Dietz syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>382398</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C2674574</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/382398">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_445391"><div><strong>Hyper-IgE recurrent infection syndrome 1, autosomal dominant</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>445391</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2936739</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">STAT3 hyper IgE syndrome (STAT3-HIES) is a primary immune deficiency syndrome characterized by elevated serum IgE, eczema, and recurrent skin and respiratory tract infections, together with several nonimmune features. This disorder typically manifests in the newborn period with a rash (often diagnosed as eosinophilic pustulosis) that subsequently evolves into an eczematoid dermatitis. Recurrent staphylococcal skin boils and bacterial pneumonias usually manifest in the first years of life. Pneumatoceles and bronchiectasis often result from aberrant healing of pneumonias. Mucocutaneous candidiasis is common. Nonimmune features may include retained primary teeth, scoliosis, bone fractures following minimal trauma, joint hyperextensibility, and characteristic facial appearance, which typically emerges in adolescence. Vascular abnormalities have been described and include middle-sized artery tortuosity and aneurysms, with infrequent clinical sequelae of myocardial infarction and subarachnoid hemorrhage. Gastrointestinal (GI) manifestations include gastroesophageal reflux disease, esophageal dysmotility, and spontaneous intestinal perforations (some of which are associated with diverticuli). Fungal infections of the GI tract (typically histoplasmosis, Cryptococcus, and Coccidioides) also occur infrequently. Survival is typically into adulthood, with most individuals now living into or past the sixth decade. Most deaths are associated with gram-negative (Pseudomonas) or filamentous fungal pneumonias resulting in hemoptysis. Lymphomas occur at an increased frequency.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/445391">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462437"><div><strong>Aneurysm-osteoarthritis syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462437</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151087</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462437">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_766676"><div><strong>Loeys-Dietz syndrome 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>766676</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3553762</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/766676">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_816049"><div><strong>Severe dermatitis-multiple allergies-metabolic wasting syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816049</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3809719</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare genetic epidermal disorder with characteristics of congenital erythroderma with severe psoriasiform dermatitis, ichthyosis, severe palmoplantar keratoderma, yellow keratosis on the hands and feet, elevated immunoglobulin E, multiple food allergies, and metabolic wasting. Other variable features may include hypotrichosis, nail dystrophy, recurrent infections, mild global developmental delay, eosinophilia, nystagmus, growth impairment and cardiac defects.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/816049">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_816342"><div><strong>Rienhoff syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816342</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3810012</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/816342">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1646567"><div><strong>Loeys-Dietz syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1646567</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551955</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Loeys-Dietz syndrome (LDS) is characterized by vascular findings (cerebral, thoracic, and abdominal arterial aneurysms and/or dissections), skeletal manifestations (pectus excavatum or pectus carinatum, scoliosis, joint laxity, arachnodactyly, talipes equinovarus, and cervical spine malformation and/or instability), craniofacial features (hypertelorism, strabismus, bifid uvula / cleft palate, and craniosynostosis that can involve any sutures), and cutaneous findings (velvety and translucent skin, easy bruising, and dystrophic scars). Individuals with LDS are predisposed to widespread and aggressive arterial aneurysms and pregnancy-related complications including uterine rupture and death. Individuals with LDS can show a strong predisposition for allergic/inflammatory disease including asthma, eczema, and reactions to food or environmental allergens. There is also an increased incidence of gastrointestinal inflammation including eosinophilic esophagitis and gastritis or inflammatory bowel disease. Wide variation in the distribution and severity of clinical features can be seen in individuals with LDS, even among affected individuals within a family who have the same pathogenic variant.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1646567">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648410"><div><strong>Combined immunodeficiency due to DOCK8 deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648410</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4722305</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyper-IgE syndrome-2 with recurrent infections (HIES2) is an autosomal recessive immunologic disorder characterized by recurrent staphylococcal infections of the skin and respiratory tract, eczema, elevated serum immunoglobulin E, and hypereosinophilia. It is distinguished from autosomal dominant HIES1 (147060) by the lack of connective tissue and skeletal involvement (Renner et al., 2004). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see 147060. See also TYK2 deficiency (611521), a clinically distinct disease entity that includes characteristic features of both autosomal recessive HIES2 and mendelian susceptibility to mycobacterial disease (MSMD; 209950) (Minegishi et al., 2006).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648410">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648434"><div><strong>Inflammatory bowel disease, immunodeficiency, and encephalopathy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648434</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4748708</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare genetic disease characterized by infantile onset of severe inflammatory bowel disease manifesting with bloody diarrhea and failure to thrive, and central nervous system disease with global developmental delay and regression, impaired speech, hypotonia, hyperreflexia, and epilepsy. Brain imaging shows global cerebral atrophy, thin corpus callosum, delayed myelination, and posterior leukoencephalopathy. Cases with recurrent infections and impaired T-cell responses to stimulation, as well as decreased T-cell subsets, have been reported.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648434">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1851769"><div><strong>Hyper-IgE syndrome 6, autosomal dominant, with recurrent infections</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1851769</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5848786</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyper-IgE syndrome-6 with recurrent infections (HIES6) is an autosomal dominant immunologic disorder characterized by early-childhood onset of severe refractory atopic dermatitis, IgE-mediated food and drug allergies, asthma, and eosinophilic esophagitis. Laboratory studies show increased serum IgE levels and eosinophilia. Affected individuals are susceptible to life-threatening anaphylaxis. Additional features may include allergic rhinitis, recurrent secondary infections (bacterial, viral, fungal), and short stature. Rare patients show intracerebral vascular abnormalities, including the Circle of Willis, increased risk of ruptured aneurysm, and B-cell lymphoma. The disorder results from immune dysregulation with inappropriate activation of inflammatory signaling pathways associated with a Th2 phenotype. Treatment with an IL4 (147780)/IL13 (147683) inhibitor (dupilumab) or JAK inhibitor results in clinical improvement. Sharma et al. (2023) classified this disease as a 'primary atopic disorder' (PAD). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see HIES1 (147060).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1851769">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462437" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Aneurysm-osteoarthritis syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648410" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Combined immunodeficiency due to DOCK8 deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_445391" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyper-IgE recurrent infection syndrome 1, autosomal dominant</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1851769" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyper-IgE syndrome 6, autosomal dominant, with recurrent infections</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648434" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Inflammatory bowel disease, immunodeficiency, and encephalopathy</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (10)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1646567" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Loeys-Dietz syndrome 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_382398" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Loeys-Dietz syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_766676" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Loeys-Dietz syndrome 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816342" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Rienhoff syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816049" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Severe dermatitis-multiple allergies-metabolic wasting syndrome</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38923067">Diagnosis and management of eosinophilic esophagitis in children: An update from the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Amil-Dias J,
|
||
Oliva S,
|
||
Papadopoulou A,
|
||
Thomson M,
|
||
Gutiérrez-Junquera C,
|
||
Kalach N,
|
||
Orel R,
|
||
Auth MK,
|
||
Nijenhuis-Hendriks D,
|
||
Strisciuglio C,
|
||
Bauraind O,
|
||
Chong S,
|
||
Ortega GD,
|
||
Férnandez SF,
|
||
Furman M,
|
||
Garcia-Puig R,
|
||
Gottrand F,
|
||
Homan M,
|
||
Huysentruyt K,
|
||
Kostovski A,
|
||
Otte S,
|
||
Rea F,
|
||
Roma E,
|
||
Romano C,
|
||
Tzivinikos C,
|
||
Urbonas V,
|
||
Velde SV,
|
||
Zangen T,
|
||
Zevit N</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2024 Aug;79(2):394-437.
|
||
Epub 2024 Jun 24
|
||
doi: 10.1002/jpn3.12188.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38923067" target="_blank">38923067</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30827775">Eosinophilic esophagitis: Pathophysiology, diagnosis, and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vinit C,
|
||
Dieme A,
|
||
Courbage S,
|
||
Dehaine C,
|
||
Dufeu CM,
|
||
Jacquemot S,
|
||
Lajus M,
|
||
Montigny L,
|
||
Payen E,
|
||
Yang DD,
|
||
Dupont C</span><br />
|
||
<span class="medgenPMjournal">Arch Pediatr</span>
|
||
2019 Apr;26(3):182-190.
|
||
Epub 2019 Mar 1
|
||
doi: 10.1016/j.arcped.2019.02.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30827775" target="_blank">30827775</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29290036">Eosinophilic Esophagitis Clinical Manifestations and Differential Diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muñoz-Mendoza D,
|
||
Chapa-Rodríguez A,
|
||
Bahna SL</span><br />
|
||
<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
|
||
2018 Aug;55(1):7-18.
|
||
doi: 10.1007/s12016-017-8663-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29290036" target="_blank">29290036</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(eosinophilic%20infiltration%20of%20the%20esophagus)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (28)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38923067">Diagnosis and management of eosinophilic esophagitis in children: An update from the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Amil-Dias J,
|
||
Oliva S,
|
||
Papadopoulou A,
|
||
Thomson M,
|
||
Gutiérrez-Junquera C,
|
||
Kalach N,
|
||
Orel R,
|
||
Auth MK,
|
||
Nijenhuis-Hendriks D,
|
||
Strisciuglio C,
|
||
Bauraind O,
|
||
Chong S,
|
||
Ortega GD,
|
||
Férnandez SF,
|
||
Furman M,
|
||
Garcia-Puig R,
|
||
Gottrand F,
|
||
Homan M,
|
||
Huysentruyt K,
|
||
Kostovski A,
|
||
Otte S,
|
||
Rea F,
|
||
Roma E,
|
||
Romano C,
|
||
Tzivinikos C,
|
||
Urbonas V,
|
||
Velde SV,
|
||
Zangen T,
|
||
Zevit N</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Gastroenterol Nutr</span>
|
||
2024 Aug;79(2):394-437.
|
||
Epub 2024 Jun 24
|
||
doi: 10.1002/jpn3.12188.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38923067" target="_blank">38923067</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38623060">Long-term Outcome of Asymptomatic Esophageal Eosinophilia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Suzuki Y,
|
||
Ochiai Y,
|
||
Kikuchi D,
|
||
Koseki M,
|
||
Ohashi K,
|
||
Hoteya S</span><br />
|
||
<span class="medgenPMjournal">Gut Liver</span>
|
||
2024 Jul 15;18(4):632-641.
|
||
Epub 2024 Apr 16
|
||
doi: 10.5009/gnl230398.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38623060" target="_blank">38623060</a><a href="/pmc/articles/PMC11249940" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31642786">Eosinophilic Gastrointestinal Diseases in Children: A Practical Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Licari A,
|
||
Votto M,
|
||
D'Auria E,
|
||
Castagnoli R,
|
||
Caimmi SME,
|
||
Marseglia GL</span><br />
|
||
<span class="medgenPMjournal">Curr Pediatr Rev</span>
|
||
2020;16(2):106-114.
|
||
doi: 10.2174/1573396315666191022154432.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31642786" target="_blank">31642786</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31593702">Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hirano I,
|
||
Dellon ES,
|
||
Hamilton JD,
|
||
Collins MH,
|
||
Peterson K,
|
||
Chehade M,
|
||
Schoepfer AM,
|
||
Safroneeva E,
|
||
Rothenberg ME,
|
||
Falk GW,
|
||
Assouline-Dayan Y,
|
||
Zhao Q,
|
||
Chen Z,
|
||
Swanson BN,
|
||
Pirozzi G,
|
||
Mannent L,
|
||
Graham NMH,
|
||
Akinlade B,
|
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Stahl N,
|
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Yancopoulos GD,
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Radin A</span><br />
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<span class="medgenPMjournal">Gastroenterology</span>
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2020 Jan;158(1):111-122.e10.
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Epub 2019 Oct 5
|
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doi: 10.1053/j.gastro.2019.09.042.
|
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<span class="bold">PMID: </span><a href="/pubmed/31593702" target="_blank">31593702</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/30903439">Eosinophilic Gastrointestinal Disorders.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gonsalves N</span><br />
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<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
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2019 Oct;57(2):272-285.
|
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doi: 10.1007/s12016-019-08732-1.
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<span class="bold">PMID: </span><a href="/pubmed/30903439" target="_blank">30903439</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Eosinophilic%20infiltration%20of%20the%20esophagus%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (126)</a></div><h3 class="subhead">Diagnosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38923067">Diagnosis and management of eosinophilic esophagitis in children: An update from the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN).</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/38923067" target="_blank">38923067</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31642786">Eosinophilic Gastrointestinal Diseases in Children: A Practical Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Licari A,
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Votto M,
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D'Auria E,
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Castagnoli R,
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Caimmi SME,
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<div class="nl"><a target="_blank" href="/pubmed/30903439">Eosinophilic Gastrointestinal Disorders.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gonsalves N</span><br />
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2019 Oct;57(2):272-285.
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doi: 10.1007/s12016-019-08732-1.
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<span class="bold">PMID: </span><a href="/pubmed/30903439" target="_blank">30903439</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28502433">Eosinophilic Gastrointestinal Disorders.</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/28502433" target="_blank">28502433</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/15833687">Eosinophilic gastroenteritis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Khan S</span><br />
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Eosinophilic%20infiltration%20of%20the%20esophagus%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (238)</a></div><h3 class="subhead">Therapy</h3>
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<div class="nl"><a target="_blank" href="/pubmed/31593702">Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hirano I,
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Dellon ES,
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Hamilton JD,
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Collins MH,
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Peterson K,
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Chehade M,
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Schoepfer AM,
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Safroneeva E,
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Rothenberg ME,
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Falk GW,
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Assouline-Dayan Y,
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Zhao Q,
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Chen Z,
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Swanson BN,
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Pirozzi G,
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Mannent L,
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Graham NMH,
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Akinlade B,
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Stahl N,
|
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Yancopoulos GD,
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Radin A</span><br />
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<span class="medgenPMjournal">Gastroenterology</span>
|
||
2020 Jan;158(1):111-122.e10.
|
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Epub 2019 Oct 5
|
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doi: 10.1053/j.gastro.2019.09.042.
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||
<span class="bold">PMID: </span><a href="/pubmed/31593702" target="_blank">31593702</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/31175521">Eosinophilic Esophagitis: the Potential Role of Biologics in its Treatment.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Choudhury S,
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Baker S</span><br />
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<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
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2020 Oct;59(2):150-159.
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doi: 10.1007/s12016-019-08749-6.
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<span class="bold">PMID: </span><a href="/pubmed/31175521" target="_blank">31175521</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30903439">Eosinophilic Gastrointestinal Disorders.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gonsalves N</span><br />
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<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
|
||
2019 Oct;57(2):272-285.
|
||
doi: 10.1007/s12016-019-08732-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30903439" target="_blank">30903439</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28502433">Eosinophilic Gastrointestinal Disorders.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Fahey LM,
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Liacouras CA</span><br />
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<span class="medgenPMjournal">Pediatr Clin North Am</span>
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2017 Jun;64(3):475-485.
|
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doi: 10.1016/j.pcl.2017.01.009.
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<span class="bold">PMID: </span><a href="/pubmed/28502433" target="_blank">28502433</a></div>
|
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<div class="nl"><a target="_blank" href="/pubmed/19554448">Eosinophilic esophagitis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Moawad FJ,
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Veerappan GR,
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<span class="medgenPMjournal">Dig Dis Sci</span>
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2009 Sep;54(9):1818-28.
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Epub 2009 Jun 25
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doi: 10.1007/s10620-009-0873-6.
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<span class="bold">PMID: </span><a href="/pubmed/19554448" target="_blank">19554448</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Eosinophilic%20infiltration%20of%20the%20esophagus%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (105)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38623060">Long-term Outcome of Asymptomatic Esophageal Eosinophilia.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Suzuki Y,
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Ochiai Y,
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Kikuchi D,
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Koseki M,
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Ohashi K,
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Hoteya S</span><br />
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2024 Jul 15;18(4):632-641.
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Epub 2024 Apr 16
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doi: 10.5009/gnl230398.
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<span class="bold">PMID: </span><a href="/pubmed/38623060" target="_blank">38623060</a><a href="/pmc/articles/PMC11249940" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31642786">Eosinophilic Gastrointestinal Diseases in Children: A Practical Review.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Licari A,
|
||
Votto M,
|
||
D'Auria E,
|
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Castagnoli R,
|
||
Caimmi SME,
|
||
Marseglia GL</span><br />
|
||
<span class="medgenPMjournal">Curr Pediatr Rev</span>
|
||
2020;16(2):106-114.
|
||
doi: 10.2174/1573396315666191022154432.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31642786" target="_blank">31642786</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31175521">Eosinophilic Esophagitis: the Potential Role of Biologics in its Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Choudhury S,
|
||
Baker S</span><br />
|
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<span class="medgenPMjournal">Clin Rev Allergy Immunol</span>
|
||
2020 Oct;59(2):150-159.
|
||
doi: 10.1007/s12016-019-08749-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31175521" target="_blank">31175521</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29549437">Treatment of eosinophilic esophagitis in the pediatric patient: an evidence-based approach.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Munoz-Persy M,
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Lucendo AJ</span><br />
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<span class="medgenPMjournal">Eur J Pediatr</span>
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2018 May;177(5):649-663.
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Epub 2018 Mar 17
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doi: 10.1007/s00431-018-3129-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29549437" target="_blank">29549437</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24603381">Eosinophilic esophagitis: asthma of the esophagus?</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Virchow JC</span><br />
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<span class="medgenPMjournal">Dig Dis</span>
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2014;32(1-2):54-60.
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Epub 2014 Feb 28
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doi: 10.1159/000357010.
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<span class="bold">PMID: </span><a href="/pubmed/24603381" target="_blank">24603381</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Eosinophilic%20infiltration%20of%20the%20esophagus%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (75)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38623060">Long-term Outcome of Asymptomatic Esophageal Eosinophilia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Suzuki Y,
|
||
Ochiai Y,
|
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Kikuchi D,
|
||
Koseki M,
|
||
Ohashi K,
|
||
Hoteya S</span><br />
|
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<span class="medgenPMjournal">Gut Liver</span>
|
||
2024 Jul 15;18(4):632-641.
|
||
Epub 2024 Apr 16
|
||
doi: 10.5009/gnl230398.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38623060" target="_blank">38623060</a><a href="/pmc/articles/PMC11249940" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31593702">Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hirano I,
|
||
Dellon ES,
|
||
Hamilton JD,
|
||
Collins MH,
|
||
Peterson K,
|
||
Chehade M,
|
||
Schoepfer AM,
|
||
Safroneeva E,
|
||
Rothenberg ME,
|
||
Falk GW,
|
||
Assouline-Dayan Y,
|
||
Zhao Q,
|
||
Chen Z,
|
||
Swanson BN,
|
||
Pirozzi G,
|
||
Mannent L,
|
||
Graham NMH,
|
||
Akinlade B,
|
||
Stahl N,
|
||
Yancopoulos GD,
|
||
Radin A</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2020 Jan;158(1):111-122.e10.
|
||
Epub 2019 Oct 5
|
||
doi: 10.1053/j.gastro.2019.09.042.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31593702" target="_blank">31593702</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29549437">Treatment of eosinophilic esophagitis in the pediatric patient: an evidence-based approach.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Munoz-Persy M,
|
||
Lucendo AJ</span><br />
|
||
<span class="medgenPMjournal">Eur J Pediatr</span>
|
||
2018 May;177(5):649-663.
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||
Epub 2018 Mar 17
|
||
doi: 10.1007/s00431-018-3129-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29549437" target="_blank">29549437</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29129299">Endoscopic and Radiologic Findings in Eosinophilic Esophagitis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Alexander JA</span><br />
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<span class="medgenPMjournal">Gastrointest Endosc Clin N Am</span>
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2018 Jan;28(1):47-57.
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Epub 2017 Oct 21
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<span class="bold">PMID: </span><a href="/pubmed/29129299" target="_blank">29129299</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/24603381">Eosinophilic esophagitis: asthma of the esophagus?</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Virchow JC</span><br />
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<span class="medgenPMjournal">Dig Dis</span>
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2014;32(1-2):54-60.
|
||
Epub 2014 Feb 28
|
||
doi: 10.1159/000357010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24603381" target="_blank">24603381</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Eosinophilic%20infiltration%20of%20the%20esophagus%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (101)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
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||
<div class="nl"><a target="_blank" href="/pubmed/38709421">Efficacy and Safety of Monoclonal Antibodies for the Treatment of Eosinophilic Esophagitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">de Oliveira FD,
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Costa RC,
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de Santana Sato EDB,
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Khalil SM,
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Meine GC</span><br />
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<span class="medgenPMjournal">Dig Dis Sci</span>
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2024 Jul;69(7):2530-2539.
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Epub 2024 May 6
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doi: 10.1007/s10620-024-08413-w.
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||
<span class="bold">PMID: </span><a href="/pubmed/38709421" target="_blank">38709421</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/36168184">Association between eosinophilic esophagitis and esophageal dysmotility: A systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Reddy SB,
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Ketchem CJ,
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Dougherty MK,
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Eluri S,
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<span class="medgenPMjournal">Neurogastroenterol Motil</span>
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2023 Feb;35(2):e14475.
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<span class="bold">PMID: </span><a href="/pubmed/36168184" target="_blank">36168184</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32089415">Granular cell tumor a study of 42 cases and systemic review of the literature.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Mobarki M,
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Dumollard JM,
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Dal Col P,
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Camy F,
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2020 Apr;216(4):152865.
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<span class="bold">PMID: </span><a href="/pubmed/32089415" target="_blank">32089415</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28383396">Role of endoscopic esophageal dilation in managing eosinophilic esophagitis: A systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Moole H,
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Jacob K,
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Duvvuri A,
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Moole V,
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Dharmapuri S,
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Boddireddy R,
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Uppu A,
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<div class="nl"><a target="_blank" href="/pubmed/24534634">Efficacy of dietary interventions for inducing histologic remission in patients with eosinophilic esophagitis: a systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Arias A,
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González-Cervera J,
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Tenias JM,
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<span class="medgenPMjournal">Gastroenterology</span>
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||
Epub 2014 Feb 15
|
||
doi: 10.1053/j.gastro.2014.02.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24534634" target="_blank">24534634</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Eosinophilic%20infiltration%20of%20the%20esophagus%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div></div>
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