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<!--
|
||
UID=1612003
|
||
ConceptID=C4524681
|
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-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Breast Carcinoma Metastatic in the Central Nervous System</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1612003</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4524681</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Breast Carcinoma Metastatic in the CNS</td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A carcinoma that has spread to the central nervous system from its original site in the breast, through the hematogenous route. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Breast Carcinoma Metastatic in the Central Nervous System</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/871338" ref="tree=MeSH" title="MedGen record for Abnormality of the breast">Abnormality of the breast</a></span><ul><li><span class="TLline"><a href="/medgen/1627648" ref="tree=MeSH" title="MedGen record for Abnormal breast morphology">Abnormal breast morphology</a></span><ul><li><span class="TLline"><a href="/medgen/264172" ref="tree=MeSH" title="MedGen record for Breast neoplasm">Breast neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/146260" ref="tree=MeSH" title="MedGen record for Breast carcinoma">Breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1651514" ref="tree=MeSH" title="MedGen record for Metastatic Breast Carcinoma">Metastatic Breast Carcinoma</a></span><ul><li><span class="matched_ds">Breast Carcinoma Metastatic in the Central Nervous System</span><ul><li><span class="TLline"><a href="/medgen/234049" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Brain">Breast Carcinoma Metastatic in the Brain</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_105">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35238866">Diagnosis and Treatment of ERBB2-Positive Metastatic Colorectal Cancer: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Strickler JH,
|
||
Yoshino T,
|
||
Graham RP,
|
||
Siena S,
|
||
Bekaii-Saab T</span><br />
|
||
<span class="medgenPMjournal">JAMA Oncol</span>
|
||
2022 May 1;8(5):760-769.
|
||
doi: 10.1001/jamaoncol.2021.8196.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35238866" target="_blank">35238866</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31617564">Cancer-related cognitive impairment: an update on state of the art, detection, and management strategies in cancer survivors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lange M,
|
||
Joly F,
|
||
Vardy J,
|
||
Ahles T,
|
||
Dubois M,
|
||
Tron L,
|
||
Winocur G,
|
||
De Ruiter MB,
|
||
Castel H</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2019 Dec 1;30(12):1925-1940.
|
||
doi: 10.1093/annonc/mdz410.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31617564" target="_blank">31617564</a><a href="/pmc/articles/PMC8109411" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29604436">Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah N,
|
||
Mohammad AS,
|
||
Saralkar P,
|
||
Sprowls SA,
|
||
Vickers SD,
|
||
John D,
|
||
Tallman RM,
|
||
Lucke-Wold BP,
|
||
Jarrell KE,
|
||
Pinti M,
|
||
Nolan RL,
|
||
Lockman PR</span><br />
|
||
<span class="medgenPMjournal">Pharmacol Res</span>
|
||
2018 Jun;132:47-68.
|
||
Epub 2018 Mar 28
|
||
doi: 10.1016/j.phrs.2018.03.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29604436" target="_blank">29604436</a><a href="/pmc/articles/PMC5997530" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(breast%20carcinoma%20metastatic%20in%20the%20central%20nervous%20system)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (139)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39271844">Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harbeck N,
|
||
Ciruelos E,
|
||
Jerusalem G,
|
||
Müller V,
|
||
Niikura N,
|
||
Viale G,
|
||
Bartsch R,
|
||
Kurzeder C,
|
||
Higgins MJ,
|
||
Connolly RM,
|
||
Baron-Hay S,
|
||
Gión M,
|
||
Guarneri V,
|
||
Bianchini G,
|
||
Wildiers H,
|
||
Escrivá-de-Romaní S,
|
||
Prahladan M,
|
||
Bridge H,
|
||
Kuptsova-Clarkson N,
|
||
Scotto N,
|
||
Verma S,
|
||
Lin NU;
|
||
DESTINY-Breast12 study group</span><br />
|
||
<span class="medgenPMjournal">Nat Med</span>
|
||
2024 Dec;30(12):3717-3727.
|
||
Epub 2024 Sep 13
|
||
doi: 10.1038/s41591-024-03261-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39271844" target="_blank">39271844</a><a href="/pmc/articles/PMC11645283" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34380530">Implementing antibody-drug conjugates (ADCs) in HER2-positive breast cancer: state of the art and future directions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ferraro E,
|
||
Drago JZ,
|
||
Modi S</span><br />
|
||
<span class="medgenPMjournal">Breast Cancer Res</span>
|
||
2021 Aug 11;23(1):84.
|
||
doi: 10.1186/s13058-021-01459-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34380530" target="_blank">34380530</a><a href="/pmc/articles/PMC8356386" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31969331">ANG1005, a Brain-Penetrating Peptide-Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kumthekar P,
|
||
Tang SC,
|
||
Brenner AJ,
|
||
Kesari S,
|
||
Piccioni DE,
|
||
Anders C,
|
||
Carrillo J,
|
||
Chalasani P,
|
||
Kabos P,
|
||
Puhalla S,
|
||
Tkaczuk K,
|
||
Garcia AA,
|
||
Ahluwalia MS,
|
||
Wefel JS,
|
||
Lakhani N,
|
||
Ibrahim N</span><br />
|
||
<span class="medgenPMjournal">Clin Cancer Res</span>
|
||
2020 Jun 15;26(12):2789-2799.
|
||
Epub 2020 Jan 22
|
||
doi: 10.1158/1078-0432.CCR-19-3258.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31969331" target="_blank">31969331</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31617564">Cancer-related cognitive impairment: an update on state of the art, detection, and management strategies in cancer survivors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lange M,
|
||
Joly F,
|
||
Vardy J,
|
||
Ahles T,
|
||
Dubois M,
|
||
Tron L,
|
||
Winocur G,
|
||
De Ruiter MB,
|
||
Castel H</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2019 Dec 1;30(12):1925-1940.
|
||
doi: 10.1093/annonc/mdz410.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31617564" target="_blank">31617564</a><a href="/pmc/articles/PMC8109411" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29931605">Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ollila TA,
|
||
Olszewski AJ</span><br />
|
||
<span class="medgenPMjournal">Curr Treat Options Oncol</span>
|
||
2018 Jun 21;19(8):38.
|
||
doi: 10.1007/s11864-018-0555-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29931605" target="_blank">29931605</a><a href="/pmc/articles/PMC6294323" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Central%20Nervous%20System%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (510)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37366925">Leptomeningeal Metastasis: A Review of the Pathophysiology, Diagnostic Methodology, and Therapeutic Landscape.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nguyen A,
|
||
Nguyen A,
|
||
Dada OT,
|
||
Desai PD,
|
||
Ricci JC,
|
||
Godbole NB,
|
||
Pierre K,
|
||
Lucke-Wold B</span><br />
|
||
<span class="medgenPMjournal">Curr Oncol</span>
|
||
2023 Jun 19;30(6):5906-5931.
|
||
doi: 10.3390/curroncol30060442.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37366925" target="_blank">37366925</a><a href="/pmc/articles/PMC10297027" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31654711">Brain malignancies: Glioblastoma and brain metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lah TT,
|
||
Novak M,
|
||
Breznik B</span><br />
|
||
<span class="medgenPMjournal">Semin Cancer Biol</span>
|
||
2020 Feb;60:262-273.
|
||
Epub 2019 Oct 22
|
||
doi: 10.1016/j.semcancer.2019.10.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31654711" target="_blank">31654711</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29931605">Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ollila TA,
|
||
Olszewski AJ</span><br />
|
||
<span class="medgenPMjournal">Curr Treat Options Oncol</span>
|
||
2018 Jun 21;19(8):38.
|
||
doi: 10.1007/s11864-018-0555-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29931605" target="_blank">29931605</a><a href="/pmc/articles/PMC6294323" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29604436">Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah N,
|
||
Mohammad AS,
|
||
Saralkar P,
|
||
Sprowls SA,
|
||
Vickers SD,
|
||
John D,
|
||
Tallman RM,
|
||
Lucke-Wold BP,
|
||
Jarrell KE,
|
||
Pinti M,
|
||
Nolan RL,
|
||
Lockman PR</span><br />
|
||
<span class="medgenPMjournal">Pharmacol Res</span>
|
||
2018 Jun;132:47-68.
|
||
Epub 2018 Mar 28
|
||
doi: 10.1016/j.phrs.2018.03.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29604436" target="_blank">29604436</a><a href="/pmc/articles/PMC5997530" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29362920">Leptomeningeal Metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Graber JJ,
|
||
Kesari S</span><br />
|
||
<span class="medgenPMjournal">Curr Treat Options Oncol</span>
|
||
2018 Jan 23;19(1):3.
|
||
doi: 10.1007/s11864-018-0518-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29362920" target="_blank">29362920</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Central%20Nervous%20System%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (543)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39271844">Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harbeck N,
|
||
Ciruelos E,
|
||
Jerusalem G,
|
||
Müller V,
|
||
Niikura N,
|
||
Viale G,
|
||
Bartsch R,
|
||
Kurzeder C,
|
||
Higgins MJ,
|
||
Connolly RM,
|
||
Baron-Hay S,
|
||
Gión M,
|
||
Guarneri V,
|
||
Bianchini G,
|
||
Wildiers H,
|
||
Escrivá-de-Romaní S,
|
||
Prahladan M,
|
||
Bridge H,
|
||
Kuptsova-Clarkson N,
|
||
Scotto N,
|
||
Verma S,
|
||
Lin NU;
|
||
DESTINY-Breast12 study group</span><br />
|
||
<span class="medgenPMjournal">Nat Med</span>
|
||
2024 Dec;30(12):3717-3727.
|
||
Epub 2024 Sep 13
|
||
doi: 10.1038/s41591-024-03261-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39271844" target="_blank">39271844</a><a href="/pmc/articles/PMC11645283" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37870091">Systematic characterization of antibody-drug conjugate targets in central nervous system tumors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Coy S,
|
||
Lee JS,
|
||
Chan SJ,
|
||
Woo T,
|
||
Jones J,
|
||
Alexandrescu S,
|
||
Wen PY,
|
||
Sorger PK,
|
||
Ligon KL,
|
||
Santagata S</span><br />
|
||
<span class="medgenPMjournal">Neuro Oncol</span>
|
||
2024 Mar 4;26(3):458-472.
|
||
doi: 10.1093/neuonc/noad205.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37870091" target="_blank">37870091</a><a href="/pmc/articles/PMC10912007" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34953200">Targeting brain metastases in breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Corti C,
|
||
Antonarelli G,
|
||
Criscitiello C,
|
||
Lin NU,
|
||
Carey LA,
|
||
Cortés J,
|
||
Poortmans P,
|
||
Curigliano G</span><br />
|
||
<span class="medgenPMjournal">Cancer Treat Rev</span>
|
||
2022 Feb;103:102324.
|
||
Epub 2021 Dec 16
|
||
doi: 10.1016/j.ctrv.2021.102324.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34953200" target="_blank">34953200</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34380530">Implementing antibody-drug conjugates (ADCs) in HER2-positive breast cancer: state of the art and future directions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ferraro E,
|
||
Drago JZ,
|
||
Modi S</span><br />
|
||
<span class="medgenPMjournal">Breast Cancer Res</span>
|
||
2021 Aug 11;23(1):84.
|
||
doi: 10.1186/s13058-021-01459-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34380530" target="_blank">34380530</a><a href="/pmc/articles/PMC8356386" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29604436">Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah N,
|
||
Mohammad AS,
|
||
Saralkar P,
|
||
Sprowls SA,
|
||
Vickers SD,
|
||
John D,
|
||
Tallman RM,
|
||
Lucke-Wold BP,
|
||
Jarrell KE,
|
||
Pinti M,
|
||
Nolan RL,
|
||
Lockman PR</span><br />
|
||
<span class="medgenPMjournal">Pharmacol Res</span>
|
||
2018 Jun;132:47-68.
|
||
Epub 2018 Mar 28
|
||
doi: 10.1016/j.phrs.2018.03.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29604436" target="_blank">29604436</a><a href="/pmc/articles/PMC5997530" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Central%20Nervous%20System%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (567)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37366925">Leptomeningeal Metastasis: A Review of the Pathophysiology, Diagnostic Methodology, and Therapeutic Landscape.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nguyen A,
|
||
Nguyen A,
|
||
Dada OT,
|
||
Desai PD,
|
||
Ricci JC,
|
||
Godbole NB,
|
||
Pierre K,
|
||
Lucke-Wold B</span><br />
|
||
<span class="medgenPMjournal">Curr Oncol</span>
|
||
2023 Jun 19;30(6):5906-5931.
|
||
doi: 10.3390/curroncol30060442.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37366925" target="_blank">37366925</a><a href="/pmc/articles/PMC10297027" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34953200">Targeting brain metastases in breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Corti C,
|
||
Antonarelli G,
|
||
Criscitiello C,
|
||
Lin NU,
|
||
Carey LA,
|
||
Cortés J,
|
||
Poortmans P,
|
||
Curigliano G</span><br />
|
||
<span class="medgenPMjournal">Cancer Treat Rev</span>
|
||
2022 Feb;103:102324.
|
||
Epub 2021 Dec 16
|
||
doi: 10.1016/j.ctrv.2021.102324.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34953200" target="_blank">34953200</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29931605">Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ollila TA,
|
||
Olszewski AJ</span><br />
|
||
<span class="medgenPMjournal">Curr Treat Options Oncol</span>
|
||
2018 Jun 21;19(8):38.
|
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doi: 10.1007/s11864-018-0555-8.
|
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|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29604436">Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah N,
|
||
Mohammad AS,
|
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Saralkar P,
|
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Sprowls SA,
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Vickers SD,
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John D,
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Tallman RM,
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Lucke-Wold BP,
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Pinti M,
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|
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2018 Jun;132:47-68.
|
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Epub 2018 Mar 28
|
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doi: 10.1016/j.phrs.2018.03.021.
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<span class="bold">PMID: </span><a href="/pubmed/29604436" target="_blank">29604436</a><a href="/pmc/articles/PMC5997530" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div class="nl"><a target="_blank" href="/pubmed/28283064">Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boire A,
|
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Zou Y,
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Shieh J,
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Macalinao DG,
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Pentsova E,
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2017 Mar 9;168(6):1101-1113.e13.
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<span class="bold">PMID: </span><a href="/pubmed/28283064" target="_blank">28283064</a><a href="/pmc/articles/PMC5405733" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Central%20Nervous%20System%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (553)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37479733">Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Song Q,
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Ruiz J,
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Xing F,
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Lo HW,
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Craddock L,
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Pullikuth AK,
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Miller LD,
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Soike MH,
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O'Neill SS,
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2023 Jul 21;6(1):760.
|
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<span class="bold">PMID: </span><a href="/pubmed/37479733" target="_blank">37479733</a><a href="/pmc/articles/PMC10362065" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/35238866">Diagnosis and Treatment of ERBB2-Positive Metastatic Colorectal Cancer: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Strickler JH,
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Yoshino T,
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Graham RP,
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Siena S,
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2022 May 1;8(5):760-769.
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doi: 10.1001/jamaoncol.2021.8196.
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<span class="bold">PMID: </span><a href="/pubmed/35238866" target="_blank">35238866</a></div>
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||
<div class="nl"><a target="_blank" href="/pubmed/31685984">Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rodrigues G,
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Hoshino A,
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Kenific CM,
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Matei IR,
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Steiner L,
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Freitas D,
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Kim HS,
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Oxley PR,
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Scandariato I,
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Dai J,
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Badwe CR,
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Gril B,
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Tešić Mark M,
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Dill BD,
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Molina H,
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Zhang H,
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Benito-Martin A,
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Bojmar L,
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Ararso Y,
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Offer K,
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LaPlant Q,
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Buehring W,
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Wang H,
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Jiang X,
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Lu TM,
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Liu Y,
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Sabari JK,
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Shin SJ,
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Narula N,
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Ginter PS,
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Rajasekhar VK,
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Healey JH,
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Meylan E,
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Costa-Silva B,
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Wang SE,
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Rafii S,
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Rudin CM,
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Jones DR,
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Steeg PS,
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Peinado H,
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Ghajar CM,
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Bromberg J,
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de Sousa M,
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Epub 2019 Nov 4
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<span class="bold">PMID: </span><a href="/pubmed/31685984" target="_blank">31685984</a><a href="/pmc/articles/PMC7354005" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29931605">Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ollila TA,
|
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Olszewski AJ</span><br />
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<span class="medgenPMjournal">Curr Treat Options Oncol</span>
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2018 Jun 21;19(8):38.
|
||
doi: 10.1007/s11864-018-0555-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29931605" target="_blank">29931605</a><a href="/pmc/articles/PMC6294323" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28283064">Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boire A,
|
||
Zou Y,
|
||
Shieh J,
|
||
Macalinao DG,
|
||
Pentsova E,
|
||
Massagué J</span><br />
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||
<span class="medgenPMjournal">Cell</span>
|
||
2017 Mar 9;168(6):1101-1113.e13.
|
||
doi: 10.1016/j.cell.2017.02.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28283064" target="_blank">28283064</a><a href="/pmc/articles/PMC5405733" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Central%20Nervous%20System%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (335)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/33073616">A Systematic Review of Peripheral Neuropathies in Breast Cancer-Related Lymphedema.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Forte AJ,
|
||
Huayllani MT,
|
||
Boczar D,
|
||
Manrique OJ,
|
||
Lu X,
|
||
McLaughlin SA,
|
||
Kung TA</span><br />
|
||
<span class="medgenPMjournal">Hand (N Y)</span>
|
||
2022 Jul;17(4):668-675.
|
||
Epub 2020 Oct 19
|
||
doi: 10.1177/1558944720963944.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33073616" target="_blank">33073616</a><a href="/pmc/articles/PMC9274882" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/30776132">Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zaheed M,
|
||
Wilcken N,
|
||
Willson ML,
|
||
O'Connell DL,
|
||
Goodwin A</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2019 Feb 18;2(2):CD012873.
|
||
doi: 10.1002/14651858.CD012873.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30776132" target="_blank">30776132</a><a href="/pmc/articles/PMC6378927" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29315431">Receptor Conversion in Distant Breast Cancer Metastases: A Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schrijver WAME,
|
||
Suijkerbuijk KPM,
|
||
van Gils CH,
|
||
van der Wall E,
|
||
Moelans CB,
|
||
van Diest PJ</span><br />
|
||
<span class="medgenPMjournal">J Natl Cancer Inst</span>
|
||
2018 Jun 1;110(6):568-580.
|
||
doi: 10.1093/jnci/djx273.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29315431" target="_blank">29315431</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26543235">Leptomeningeal metastasis in breast cancer - a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Scott BJ,
|
||
Oberheim-Bush NA,
|
||
Kesari S</span><br />
|
||
<span class="medgenPMjournal">Oncotarget</span>
|
||
2016 Jan 26;7(4):3740-7.
|
||
doi: 10.18632/oncotarget.5911.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26543235" target="_blank">26543235</a><a href="/pmc/articles/PMC4826166" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24445565">Metastatic involvement of the pituitary gland: a systematic review with pooled individual patient data analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">He W,
|
||
Chen F,
|
||
Dalm B,
|
||
Kirby PA,
|
||
Greenlee JD</span><br />
|
||
<span class="medgenPMjournal">Pituitary</span>
|
||
2015 Feb;18(1):159-68.
|
||
doi: 10.1007/s11102-014-0552-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24445565" target="_blank">24445565</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Central%20Nervous%20System%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div></div>
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