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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>National Clinical Guideline Centre (UK). Lower Limb Peripheral Arterial Disease: Diagnosis and Management [Internet]. London: Royal College of Physicians (UK); 2012 Aug. (NICE Clinical Guidelines, No. 147.)</p></div><div class="bk_msg_box bk_bttm_mrgn clearfix bk_noprnt"><div class="iconblock clearfix"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/nicecg147guid/"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg147guid-lrg.png" alt="Cover" height="100px" width="80px" /></a><div class="icnblk_cntnt"><ul class="messages"><li class="info icon"><span class="icon"><a href="/books/n/nicecg147guid/">See 2020 Partial Update</a></span></li></ul></div></div></div><div class="messagearea bk_noprnt" style="margin-bottom:1.3846em "><ul class="messages"><li class="warn icon"><span class="icon">Update information: This guideline was updated by a NICE standing committee in February 2018 and 2 new recommendations were added on diagnosing peripheral arterial disease in people with diabetes. The recommendations are in section 1.3 of the guidance. The evidence for these recommendations is in evidence reviews A: determining the diagnosis and severity of peripheral arterial disease in people with diabetes. December 2020: NICE added links in the recommendation on pain relief to other NICE guidelines and resources that support discussion with patients about opioid prescribing and safe withdrawal management. For the current recommendations, see www.nice.org.uk/guidance/CG147/chapter/recommendations. October 2018: The antiplatelet therapy link in recommendation 1.2.1 was updated.</span></li></ul></div><div class="bk_prnt"><p style="color:red;"><strong>Update information: This guideline was updated by a NICE standing committee in February 2018 and 2 new recommendations were added on diagnosing peripheral arterial disease in people with diabetes. The recommendations are in section 1.3 of the guidance. The evidence for these recommendations is in evidence reviews A: determining the diagnosis and severity of peripheral arterial disease in people with diabetes. December 2020: NICE added links in the recommendation on pain relief to other NICE guidelines and resources that support discussion with patients about opioid prescribing and safe withdrawal management. For the current recommendations, see www.nice.org.uk/guidance/CG147/chapter/recommendations. October 2018: The antiplatelet therapy link in recommendation 1.2.1 was updated.</strong></p></div><div class="iconblock clearfix whole_rhythm no_top_margin bk_noprnt"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/nicecg147/"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg147-lrg.png" alt="Cover of Lower Limb Peripheral Arterial Disease" height="100px" width="80px" /></a><div class="icnblk_cntnt eight_col"><h2>Lower Limb Peripheral Arterial Disease: Diagnosis and Management [Internet].</h2><a data-jig="ncbitoggler" href="#__NBK327433_dtls__">Show details</a><div style="display:none" class="ui-widget" id="__NBK327433_dtls__"><div>NICE Clinical Guidelines, No. 147.</div><div>National Clinical Guideline Centre (UK).</div><div>London: <a href="http://www.rcplondon.ac.uk/Pages/index.aspx" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">Royal College of Physicians (UK)</a>; 2012 Aug.</div></div><div class="half_rhythm"><ul class="inline_list"><li style="margin-right:1em"><a class="bk_cntns" href="/books/n/nicecg147/">Contents</a></li></ul></div></div><div class="icnblk_cntnt two_col"><div class="pagination bk_noprnt"><a class="active page_link prev" href="/books/n/nicecg147/appe/" title="Previous page in this title">< Prev</a><a class="active page_link next" href="/books/n/nicecg147/appg/" title="Next page in this title">Next ></a></div></div></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK327433_"><span class="label">Appendix F</span><span class="title" itemprop="name">Exclusion lists – economic evidence</span></h1></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><div id="appf.s1"><h2 id="_appf_s1_">F.1. Information requirements</h2><p>No cost-effectiveness evidence was identified for this question.</p></div><div id="appf.s2"><h2 id="_appf_s2_">F.2. Diagnosis of peripheral arterial disease</h2><p>No cost-effectiveness evidence was identified for this question.</p></div><div id="appf.s3"><h2 id="_appf_s3_">F.3. Imaging for revascularisation</h2><div id="appf.tu1" class="table"><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK327433/table/appf.tu1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__appf.tu1_lrgtbl__"><table><thead><tr><th id="hd_h_appf.tu1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Study</th><th id="hd_h_appf.tu1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Reason</th></tr></thead><tbody><tr><td headers="hd_h_appf.tu1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Berry 2002. The cost-effectiveness of magnetic resonance angiography for carotid artery stenosis and peripheral vascular disease: a systematic review. Health Technology Assessment. 6(7).</td><td headers="hd_h_appf.tu1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This HTA has been replaced by the updated Collins 2007</td></tr><tr><td headers="hd_h_appf.tu1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Coffi 2008. Cost-effectiveness of identifying aortoiliac and femoropopliteal arterial disease with angiography and duplex scanning. European Journal of Radiology. 66; 142–148.</td><td headers="hd_h_appf.tu1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Does not include QALYs as a measure of effectiveness.</td></tr><tr><td headers="hd_h_appf.tu1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hay 2009. Cost impact of diagnostic imaging for lower extremity peripheral vascular occlusive disease. Value in Health 12(2); 262 – 266</td><td headers="hd_h_appf.tu1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Retrospective cost analysis rather than cost-effectiveness analysis.</td></tr><tr><td headers="hd_h_appf.tu1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ouwendijk 2008. Multicentre randomised controlled trial of the cost and effects of noninvasive diagnostic imaging in patients with peripheral arterial disease: the DIPAD trail. American Journal of Roenterology 190(5); 1349 – 1357</td><td headers="hd_h_appf.tu1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Results not presented in such a way as to allow calculation of incremental cost and effects.</td></tr><tr><td headers="hd_h_appf.tu1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Schwartz 2009. Arterial duplex ultrasound is the most cost-effective, non-invasive diagnostic imaging modality before treatment of lower extremity arterial occlusive disease. Journal for Vascular Ultrasound. 33(2); 75–79</td><td headers="hd_h_appf.tu1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Retrospective cost analysis rather than cost-effectiveness analysis.</td></tr><tr><td headers="hd_h_appf.tu1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Vahl 2008. Contrast enhanced magnetic resonance angiography versus digital subtraction angiography for treatment planning in patients with peripheral arterial disease: A randomised controlled diagnostic trial. European Journal of Endovascular Surgery 35 (5);514 – 521</td><td headers="hd_h_appf.tu1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Includes costs but no health-related quality of life outcomes.</td></tr></tbody></table></div></div></div><div id="appf.s4"><h2 id="_appf_s4_">F.4. Management of intermittent claudication</h2><div id="appf.s5"><h3>F.4.1. Supervised exercise compared to unsupervised exercise</h3><div id="appf.tu2" class="table"><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK327433/table/appf.tu2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__appf.tu2_lrgtbl__"><table><thead><tr><th id="hd_h_appf.tu2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Study</th><th id="hd_h_appf.tu2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Reason</th></tr></thead><tbody><tr><td headers="hd_h_appf.tu2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ambrosetti 2004. Economic evaluation of a short-course intensive rehabilitation program in patients with intermittent claudication. International Angiology. 23(2); 108–113</td><td headers="hd_h_appf.tu2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wrong intervention/comparison</td></tr><tr><td headers="hd_h_appf.tu2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kakkos 2005. Improvement of the walking ability in intermittent claudication due to superficial femoral artery occlusion with supervised exercise and pneumatic foot and calf compression: a randomised controlled trial. European Journal of Vascular and Endovascular Surgery. 30(2)164–175.</td><td headers="hd_h_appf.tu2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Brief narrative about cost-effectiveness, but no costs or QALYs provided.</td></tr><tr><td headers="hd_h_appf.tu2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Roine 2009. Cost-effectiveness of interventions based on physical exercise in the treatment of various diseases: a systematic literature review. International Journal of Technology Assessment in Health Care. 25(4); 427–454.</td><td headers="hd_h_appf.tu2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No IC/PAD population.</td></tr><tr><td headers="hd_h_appf.tu2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Spronk 2008. Cost-effectiveness of new cardiac and vascular rehabilitation strategies for patients with coronary artery disease. PLoS ONE. 3(12).</td><td headers="hd_h_appf.tu2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wrong intervention/comparison</td></tr></tbody></table></div></div></div><div id="appf.s6"><h3>F.4.2. Naftidrofuryl oxalate</h3><p>No cost-effectiveness evidence was identified for this question.</p></div><div id="appf.s7"><h3>F.4.3. Comparisons of exercise, best medical treatment, angioplasty and bypass surgery</h3><div id="appf.tu3" class="table"><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK327433/table/appf.tu3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__appf.tu3_lrgtbl__"><table><thead><tr><th id="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Study</th><th id="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Reason</th></tr></thead><tbody><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Chong 2000. Exercise therapy or angioplasty? A summation analysis. European Journal of Vascular and Endovascular Surgery. 20(1); 4–12</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fry 2011. Comparative effectiveness and efficiency in peripheral vascular surgery. The American Journal of Surgery 201; 363–368.</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Retrospective cost analysis. No utility data.</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Koerkamp 2010. Value of information analyses of economic randomized controlled trials: The treatment of intermittent claudication. Value in Health. 13(2); 242–250</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Value of information analysis of included study (Spronk 2008)</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Medical Advisory Secretariat 2010. Stenting for peripheral arterial disease of the lower extremities. Ontario Health Technology Assessment Series. 10(18)</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review of economic analyses comparing angioplasty and angioplasty with selective stenting.</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mittmann 2005. Economic evaluation of drug eluting stents. Canadian Coordinating Office for Health Technology Assessment</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Coronary stents.</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">O’Brien-Irr 2008. Lower extremity endovascular interventions: can we improve cost-efficiency? Journal of Vascular Surgery 47; 982–7</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Retrospective cost analysis. No utility or comparative evaluation.</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Stoner 2008. Cost per day of patency: Understanding the impact of patency and reintervention in a sustainable model of healthcare. Journal of Vascular Surgery 41; 1489–96</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not a comparative evaluation.</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Treesak 2004. Cost-effectiveness of exercise training to improve claudication symptoms in patients with peripheral arterial disease. Vascular Medicine. 9(4); 279–285</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No QALYs; cost per metre.</td></tr><tr><td headers="hd_h_appf.tu3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Whyman 1998. Should claudicants receive angioplasty or just exercise training? Cardiovascular Surgery. 6(3); 226–231</td><td headers="hd_h_appf.tu3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review</td></tr></tbody></table></div></div></div><div id="appf.s8"><h3>F.4.4. Bare metal compared to drug eluting stents</h3><p>No cost-effectiveness evidence was identified for this question</p></div><div id="appf.s9"><h3>F.4.5. Autologous vein compared to prosthetic bypass</h3><p>No cost-effectiveness evidence was identified for this question</p></div></div><div id="appf.s10"><h2 id="_appf_s10_">F.5. Management of critical limb ischaemia</h2><div id="appf.tu4" class="table"><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK327433/table/appf.tu4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__appf.tu4_lrgtbl__"><table><thead><tr><th id="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Study</th><th id="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Reason</th></tr></thead><tbody><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Allie 2009. 24-carat gold, 14-carat gold, or platinum standards in the treatment of CLI: Bypass surgery or endovascular intervention? Journal of Endovascular Therapy 16(Suppl I):I134–I146</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review. No cost or quality of life data.</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Balland 1998. Aortoiliac stent deployment versus surgical reconstruction: analysis of outcome and cost. Journal of Vascular Surgery 28; 94–103</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Based on a non-randomised study. No QALYs. Mean total hospital costs per limb (rather than per patient) were reported</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Brothers 2007. Prospective decision analysis for peripheral vascular disease predicts future quality of life. Journal of Vascular Surgery 46; 701–8</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was designed to measure the relationship between patient’s measured utilities following intervention and model predictions. Although the model reported contains all of our interventions of interest, the model inputs and results are not reported.</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Brothers 2004. Prospective decision analysis modelling indicates that clinical decisions in vascular surgery often fail to maximize patient expected utility. Journal of Surgical Research 120; 278–87</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was designed to measure the relationship between surgeon’s decisions and model predictions. Although the model reported contains all of our interventions of interest, the model inputs and results are not reported.</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ebaugh 2008. Comparison of costs of staged versus simultaneous lower extremity arterial hybrid procedures. The American Journal of Surgery 196; 634–40</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wrong comparison (staged vs. simultaneous bypass).</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Haustein 1997. State of the art – treatment fo peripheral occlusive arterial disease (POAD) with drugs vs. vascular reconstruction or amputation. International Journal of Clinical Pharmacology and Therapeutics 35(7);266–274</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Non-systematic review; no costs.</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Muradin 2001. Cost and patency rate targets for the development of endovascular devices to treat femoropopliteal arterial disease. Radiology 218;264–9</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This a threshold analysis of the cost-effectiveness of a hypothetical endovascular device based on the model by Hunick et al (1995) and not a comparative evaluation of our interventions of interest.</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nelson 2001. Impact of endovascular-assisted in situ staphenous vein bypass technique on hospital costs. Annals of Vascular Surgery 15; 653–60</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wrong comparison (in situ vs. conventional bypass)</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nolan 2007. The treatment of disabling intermittent claudication in patients with superficial femoral artery occlusive disease – Decision analysis. Journal of Vascular Surgery 45; 1179–84</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This model included QALYs but not costs. QALYs determined using Nottingham Health Profile.</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">O’Brien-Irr 2008. Lower extremity endovascular interventions: can we improve cost-efficiency? Journal of Vascular Surgery 47; 982–7</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study did not compare the interventions of interest and was not relevant to the UK setting.</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Piano 1998. Assessing outcomes, costs, and benefits of emerging technology for minimally invasive staphenous vein in situ distal arterial bypasses. Archives of Surgery 133; 613–8</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wong comparison (in situ vs conventional bypass)</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sultan 2009. Five year Irish trial of CLI patient with TASC II Type C/D lesions undergoing subintimal angioplasty or bypass surgery based on plaque echolucency. Journal of Endovascular Therapy 16(3); 270–283</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Based on observational data, QALYs evaluated using Time Spent Without Symptoms of Disease and Toxicity of Treatment (TWiST).</td></tr><tr><td headers="hd_h_appf.tu4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Werneck 2009. Tibial angioplasty for limb salvage in high risk patients and cost analysis. Annals of Vascular Surgery 23; 554–9</td><td headers="hd_h_appf.tu4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population subgroup of patients with end-stage renal disease. Very short time horizon (mean 7.7 months), based on a retrospective analysis.</td></tr></tbody></table></div></div></div><div id="bk_toc_contnr"></div></div></div>
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<div class="post-content"><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> © 2012, National Clinical Guideline Centre.<p class="small">
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<div xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Views</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="PDF_download" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li><a href="/books/NBK327433/?report=reader">PubReader</a></li><li><a href="/books/NBK327433/?report=printable">Print View</a></li><li><a data-jig="ncbidialog" href="#_ncbi_dlg_citbx_NBK327433" data-jigconfig="width:400,modal:true">Cite this Page</a><div id="_ncbi_dlg_citbx_NBK327433" style="display:none" title="Cite this Page"><div class="bk_tt">National Clinical Guideline Centre (UK). Lower Limb Peripheral Arterial Disease: Diagnosis and Management [Internet]. London: Royal College of Physicians (UK); 2012 Aug. (NICE Clinical Guidelines, No. 147.) Appendix F, Exclusion lists – economic evidence.<span class="bk_cite_avail"></span></div></div></li><li><a href="/books/n/nicecg147/pdf/">PDF version of this title</a> (3.4M)</li></ul></div></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>In this Page</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="page-toc" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li><a href="#appf.s1" ref="log$=inpage&link_id=inpage">Information requirements</a></li><li><a href="#appf.s2" ref="log$=inpage&link_id=inpage">Diagnosis of peripheral arterial disease</a></li><li><a href="#appf.s3" ref="log$=inpage&link_id=inpage">Imaging for revascularisation</a></li><li><a href="#appf.s4" ref="log$=inpage&link_id=inpage">Management of intermittent claudication</a></li><li><a href="#appf.s10" ref="log$=inpage&link_id=inpage">Management of critical limb ischaemia</a></li></ul></div></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Other titles in this collection</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="source-links" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li><a href="/books/n/nicecollect/">
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National Institute for Health and Clinical Excellence: Guidance
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