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<meta name="robots" content="NOINDEX,NOFOLLOW,NOARCHIVE,NOIMAGEINDEX" /><meta name="author" content="School of Health and Related Research (ScHARR), University of Sheffield" /><meta name="citation_title" content="Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care" /><meta name="citation_publisher" content="University of Sheffield" /><meta name="citation_date" content="2004/05" /><meta name="citation_author" content="School of Health and Related Research (ScHARR), University of Sheffield" /><meta name="citation_pmid" content="23285501" /><meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK65452/" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="University of Sheffield" /><meta name="DC.Contributor" content="School of Health and Related Research (ScHARR), University of Sheffield" /><meta name="DC.Date" content="2004/05" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK65452/" /><meta name="DC.Language" content="en" /><meta name="description" content="The scope of this guideline was care, and classification, of women at risk of breast cancer because of family history. The guideline covers women aged 18 years and older. It does not cover women who have breast cancer. It does not cover the care and management of men who may be at risk because of family history. The guideline addresses care in primary, secondary and tertiary care in respect of these women. However, the guideline does not cover in detail some aspects of some interventions that may be relevant, for example it does not address methods of screening in detail as that is outwith the scope." /><meta name="og:title" content="Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care" /><meta name="og:type" content="book" /><meta name="og:description" content="The scope of this guideline was care, and classification, of women at risk of breast cancer because of family history. The guideline covers women aged 18 years and older. It does not cover women who have breast cancer. It does not cover the care and management of men who may be at risk because of family history. The guideline addresses care in primary, secondary and tertiary care in respect of these women. However, the guideline does not cover in detail some aspects of some interventions that may be relevant, for example it does not address methods of screening in detail as that is outwith the scope." /><meta name="og:url" content="https://www.ncbi.nlm.nih.gov/books/NBK65452/" /><meta name="og:site_name" content="NCBI Bookshelf" /><meta name="og:image" content="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg14-lrg.png" /><meta name="twitter:card" content="summary" /><meta name="twitter:site" content="@ncbibooks" /><meta name="warning" content="This publication is provided for historical reference only and the information may be out of date." /><meta name="bk-non-canon-loc" content="/books/n/nicecg14/toc/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK65452/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" media="print" /><style type="text/css">.main-content {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/css/bookshelf/2.26/img/archive.png);background-size: auto, contain; padding:0 0 0 3em }</style><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript" src="/corehtml/pmc/js/large-obj-scrollbars.min.js"> </script><script type="text/javascript">window.name="mainwindow";</script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script><meta name="book-collection" content="nicecollect" />
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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p></div><div class="bk_msg_box bk_bttm_mrgn clearfix bk_noprnt"><div class="iconblock clearfix"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/nicecg164guid/"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg164guid-lrg.png" alt="Cover" height="100px" width="80px" /></a><div class="icnblk_cntnt"><ul class="messages"><li class="info icon"><span class="icon"><a href="/books/n/nicecg164guid/">A new version of this title is available</a></span></li></ul></div></div></div><div class="messagearea bk_noprnt" style="margin-bottom:1.3846em "><ul class="messages"><li class="warn icon"><span class="icon">This publication is provided for historical reference only and the information may be out of date.</span></li></ul></div><div class="bk_prnt"><p style="color:red;"><strong>This publication is provided for historical reference only and the information may be out of date.</strong></p></div><div class="pagination bk_noprnt"><span class="inactive page_link prev">< Prev</span><a class="active page_link next" href="/books/n/nicecg14/update/" title="Next page in this title">Next ></a></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/Book"><div class="meta-content fm-sec"><div class="iconblock whole_rhythm clearfix no_top_margin"><a href="https://www.sheffield.ac.uk/scharr" title="University of Sheffield" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg14-lrg.png" alt="Cover of Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care" /></a><div class="icnblk_cntnt"><h1 id="_NBK65452_"><span itemprop="name">Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care</span></h1><p><i>NICE Clinical Guidelines, No. 14</i></p><p class="contrib-group"><span itemprop="author">School of Health and Related Research (ScHARR), University of Sheffield</span>.</p><div class="half_rhythm">Sheffield (UK): <a href="https://www.sheffield.ac.uk/scharr" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">University of Sheffield</span></a>; <span itemprop="datePublished">2004 May</span>.</div><div class="half_rhythm"><ul class="inline_list"><li><span class="label"><a data-jig="ncbidialog" href="#_ncbi_dlg_cpyrght_NBK65452" data-jigconfig="modal:true">Copyright and
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Permissions</a></span></li></ul></div><div id="_ncbi_dlg_cpyrght_NBK65452" style="display:none" title="Copyright and Permissions"><div><div>Copyright © 2004, School of Health and Related Research (ScHARR), University of Sheffield.</div><div>For more information, see the <a href="/books/about/copyright/">Bookshelf Copyright Notice</a>.</div></div></div></div></div></div><div class="body-content whole_rhythm" itemprop="text"><div itemprop="description"><h2>Excerpt</h2><p>The scope of this guideline was care, and classification, of women at <a class="def" href="/books/n/nicecg14/glossary.gl1/def-item/glossary.gl1-d27/">risk</a> of breast cancer because of <a class="def" href="/books/n/nicecg14/glossary.gl1/def-item/glossary.gl1-d7/">family history</a>. The guideline covers women aged 18 years and older. It does not cover women who have breast cancer. It does <b>not</b> cover the care and management of men who may be at risk because of family history. The guideline addresses care in primary, secondary and tertiary care in respect of these women. However, the guideline does not cover in detail some aspects of some interventions that may be relevant, for example it does not address methods of screening in detail as that is outwith the scope.</p></div><div><h2>Contents</h2><div class="bktoc_all_cntnr top align_right" style="display:none"><ul class="inline_list_right"><li><a class="bktoc_all_exp" href="#">Expand All</a></li><li style="margin-left:.8em"><a class="bktoc_all_clps" href="#">Collapse All</a></li></ul></div><ul id="toc_tllNBK65452_update" class="simple-list toc toc-toggle"><li class="half_rhythm" id="toc_itm_NBK65452_update"><a href="/books/n/nicecg14/update/" class="toc-item">October 2006 Update</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch1"><a href="/books/n/nicecg14/ch1/" class="toc-item">1. Key priorities for implementation</a><ul id="toc_lst_NBK65452_ch1_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch1_s1"><a href="/books/n/nicecg14/ch1/#ch1.s1" class="toc-item">Approaches to care</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch1_s2"><a href="/books/n/nicecg14/ch1/#ch1.s2" class="toc-item">Family history and referral</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch1_s3"><a href="/books/n/nicecg14/ch1/#ch1.s3" class="toc-item">Care</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2"><a href="/books/n/nicecg14/ch2/" class="toc-item">2. Guideline development</a><ul id="toc_lst_NBK65452_ch2_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s1"><a href="/books/n/nicecg14/ch2/#ch2.s1" class="toc-item">2.1 The guideline</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s2"><a href="/books/n/nicecg14/ch2/#ch2.s2" class="toc-item">2.2 Using guidelines</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s3"><a href="/books/n/nicecg14/ch2/#ch2.s3" class="toc-item">2.3 Responsibility and support for the guideline</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s4"><a href="/books/n/nicecg14/ch2/#ch2.s4" class="toc-item">2.4 Scope of the guideline</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s5"><a href="/books/n/nicecg14/ch2/#ch2.s5" class="toc-item">2.5 Key clinical questions</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s6"><a href="/books/n/nicecg14/ch2/#ch2.s6" class="toc-item">2.6 Evidence identification</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s11"><a href="/books/n/nicecg14/ch2/#ch2.s11" class="toc-item">2.7 Evidence grading</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s12"><a href="/books/n/nicecg14/ch2/#ch2.s12" class="toc-item">2.8 Derivation and grading of recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s13"><a href="/books/n/nicecg14/ch2/#ch2.s13" class="toc-item">2.9 Cost effectiveness review and analysis</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s18"><a href="/books/n/nicecg14/ch2/#ch2.s18" class="toc-item">2.10 Consensus in recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch2_s19"><a href="/books/n/nicecg14/ch2/#ch2.s19" class="toc-item">2.11 Guideline review</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch3"><a href="/books/n/nicecg14/ch3/" class="toc-item">3. Women with a family history of breast cancer</a><ul id="toc_lst_NBK65452_ch3_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch3_s1"><a href="/books/n/nicecg14/ch3/#ch3.s1" class="toc-item">3.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch3_s2"><a href="/books/n/nicecg14/ch3/#ch3.s2" class="toc-item">3.2 Incidence and prevalence</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch3_s3"><a href="/books/n/nicecg14/ch3/#ch3.s3" class="toc-item">3.3 The role of family history</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch3_s5"><a href="/books/n/nicecg14/ch3/#ch3.s5" class="toc-item">3.4 Impact on individuals with a family history of breast cancer</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch4"><a href="/books/n/nicecg14/ch4/" class="toc-item">4. Risk assessment and classification (including family history taking) and risk communication</a><ul id="toc_lst_NBK65452_ch4_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch4_s1"><a href="/books/n/nicecg14/ch4/#ch4.s1" class="toc-item">4.1 Risk estimation</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch4_s2"><a href="/books/n/nicecg14/ch4/#ch4.s2" class="toc-item">4.2 Risk classification</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch4_s3"><a href="/books/n/nicecg14/ch4/#ch4.s3" class="toc-item">4.3 Family history taking</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch4_s29"><a href="/books/n/nicecg14/ch4/#ch4.s29" class="toc-item">4.4 Risk assessment tools</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch4_s43"><a href="/books/n/nicecg14/ch4/#ch4.s43" class="toc-item">4.5 Risk communication</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch5"><a href="/books/n/nicecg14/ch5/" class="toc-item">5. Approaches to care and information giving</a><ul id="toc_lst_NBK65452_ch5_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch5_s1"><a href="/books/n/nicecg14/ch5/#ch5.s1" class="toc-item">5.1 Approaches to care and information giving</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch5_s4"><a href="/books/n/nicecg14/ch5/#ch5.s4" class="toc-item">5.2 Breast awareness and examination</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch6"><a href="/books/n/nicecg14/ch6/" class="toc-item">6. Care of women in primary care</a><ul id="toc_lst_NBK65452_ch6_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch6_s1"><a href="/books/n/nicecg14/ch6/#ch6.s1" class="toc-item">6.1 Care and management approach – primary care</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch6_s10"><a href="/books/n/nicecg14/ch6/#ch6.s10" class="toc-item">6.2 Patient education/information in primary care</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch7"><a href="/books/n/nicecg14/ch7/" class="toc-item">7. Care of women in specialist (secondary and tertiary) care</a><ul id="toc_lst_NBK65452_ch7_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch7_s1"><a href="/books/n/nicecg14/ch7/#ch7.s1" class="toc-item">7.1 Specialist care - care and management approach</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch7_s13"><a href="/books/n/nicecg14/ch7/#ch7.s13" class="toc-item">7.2 Surveillance (secondary care)</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch7_s65"><a href="/books/n/nicecg14/ch7/#ch7.s65" class="toc-item">7.3 Genetic counselling (tertiary care)</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch7_s80"><a href="/books/n/nicecg14/ch7/#ch7.s80" class="toc-item">7.4 Genetic testing (tertiary care)</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch7_s115"><a href="/books/n/nicecg14/ch7/#ch7.s115" class="toc-item">7.5 Risk reducing mastectomy (tertiary care)</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch7_s141"><a href="/books/n/nicecg14/ch7/#ch7.s141" class="toc-item">7.6 Risk reducing oophorectomy</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch7_s159"><a href="/books/n/nicecg14/ch7/#ch7.s159" class="toc-item">7.7 Tamoxifen (tertiary care)</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8"><a href="/books/n/nicecg14/ch8/" class="toc-item">8. Risk factors</a><ul id="toc_lst_NBK65452_ch8_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s1"><a href="/books/n/nicecg14/ch8/#ch8.s1" class="toc-item">8.1 Risk factors</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s4"><a href="/books/n/nicecg14/ch8/#ch8.s4" class="toc-item">8.2 Risk associated with family history</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s5"><a href="/books/n/nicecg14/ch8/#ch8.s5" class="toc-item">8.3 Note re research literature</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s6"><a href="/books/n/nicecg14/ch8/#ch8.s6" class="toc-item">8.4 Note re modifiable risk factors</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s7"><a href="/books/n/nicecg14/ch8/#ch8.s7" class="toc-item">8.5 Hormone replacement therapy</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s33"><a href="/books/n/nicecg14/ch8/#ch8.s33" class="toc-item">8.6 Hormonal contraceptives</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s58"><a href="/books/n/nicecg14/ch8/#ch8.s58" class="toc-item">8.7 Breastfeeding</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s68"><a href="/books/n/nicecg14/ch8/#ch8.s68" class="toc-item">8.8 Other reproductive/fertility issues</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s81"><a href="/books/n/nicecg14/ch8/#ch8.s81" class="toc-item">8.9 Alcohol consumption</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s96"><a href="/books/n/nicecg14/ch8/#ch8.s96" class="toc-item">8.10 Smoking</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s110"><a href="/books/n/nicecg14/ch8/#ch8.s110" class="toc-item">8.11 Weight and physical activity</a></li><li class="half_rhythm" id="toc_itm_NBK65452_ch8_s119"><a href="/books/n/nicecg14/ch8/#ch8.s119" class="toc-item">8.12 Menstrual/reproductive factors</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch9"><a href="/books/n/nicecg14/ch9/" class="toc-item">9. Audit criteria</a><ul id="toc_lst_NBK65452_ch9_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_ch9_s1"><a href="/books/n/nicecg14/ch9/#ch9.s1" class="toc-item">Calculation of compliance</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK65452_ch10"><a href="/books/n/nicecg14/ch10/" class="toc-item">10. Research issues</a></li><li class="half_rhythm" id="toc_itm_NBK65452_glossary_gl1"><a href="/books/n/nicecg14/glossary.gl1/" class="toc-item">11. Selected glossary</a></li><li class="half_rhythm" id="toc_itm_NBK65452_references_rl1"><a href="/books/n/nicecg14/references.rl1/" class="toc-item">12. References</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_appgroup1"><a href="/books/n/nicecg14/appendixes.appgroup1/" class="toc-item">13. Appendices</a><ul id="toc_lst_NBK65452_appendixes_app1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app1"><a href="/books/n/nicecg14/appendixes.app1/" class="toc-item">Appendix 1 Family history taking</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app2"><a href="/books/n/nicecg14/appendixes.app2/" class="toc-item">Appendix 2 Risk communication</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app3"><a href="/books/n/nicecg14/appendixes.app3/" class="toc-item">Appendix 3 Patient education/information</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app4"><a href="/books/n/nicecg14/appendixes.app4/" class="toc-item">Appendix 4 Genetic counselling</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app5"><a href="/books/n/nicecg14/appendixes.app5/" class="toc-item">Appendix 5 Surveillance</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app6"><a href="/books/n/nicecg14/appendixes.app6/" class="toc-item">Appendix 6 Genetic testing techniques</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app7"><a href="/books/n/nicecg14/appendixes.app7/" class="toc-item">Appendix 7 Genetic testing, attitudes</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app8"><a href="/books/n/nicecg14/appendixes.app8/" class="toc-item">Appendix 8 Genetic testing, psychosocial aspects</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app9"><a href="/books/n/nicecg14/appendixes.app9/" class="toc-item">Appendix 9 Risk reducing mastectomy</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app10"><a href="/books/n/nicecg14/appendixes.app10/" class="toc-item">Appendix 10 Risk reducing oophorectomy</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app11"><a href="/books/n/nicecg14/appendixes.app11/" class="toc-item">Appendix 11 Tamoxifen</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app12"><a href="/books/n/nicecg14/appendixes.app12/" class="toc-item">Appendix 12 Menstrual/reproductive factors</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app13"><a href="/books/n/nicecg14/appendixes.app13/" class="toc-item">Appendix 13 Hormone replacement therapy</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app14"><a href="/books/n/nicecg14/appendixes.app14/" class="toc-item">Appendix 14 Hormonal contraceptives</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app15"><a href="/books/n/nicecg14/appendixes.app15/" class="toc-item">Appendix 15 Breastfeeding</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app16"><a href="/books/n/nicecg14/appendixes.app16/" class="toc-item">Appendix 16 Other reproductive/fertility issues</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app17"><a href="/books/n/nicecg14/appendixes.app17/" class="toc-item">Appendix 17 Alcohol consumption</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app18"><a href="/books/n/nicecg14/appendixes.app18/" class="toc-item">Appendix 18 Smoking</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app19"><a href="/books/n/nicecg14/appendixes.app19/" class="toc-item">Appendix 19 Obesity</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app20"><a href="/books/n/nicecg14/appendixes.app20/" class="toc-item">Appendix 20 Estimating the Cost Effectiveness of Genetic Testing for BRCA1/BRCA2</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app21"><a href="/books/n/nicecg14/appendixes.app21/" class="toc-item">Appendix 21 Guideline development group</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app22"><a href="/books/n/nicecg14/appendixes.app22/" class="toc-item">Appendix 22 Scope</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app23"><a href="/books/n/nicecg14/appendixes.app23/" class="toc-item">Appendix 23 Related NICE guidance</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app24"><a href="/books/n/nicecg14/appendixes.app24/" class="toc-item">Appendix 24 Literature searches</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app25"><a href="/books/n/nicecg14/appendixes.app25/" class="toc-item">Appendix 25 Risk estimates table</a></li><li class="half_rhythm" id="toc_itm_NBK65452_appendixes_app26"><a href="/books/n/nicecg14/appendixes.app26/" class="toc-item">Appendix 26 Breast cancer risk categorisation</a></li></ul></li></ul><div class="bktoc_all_cntnr align_right" style="display:none"><ul class="inline_list_right"><li><a class="bktoc_all_exp" href="#">Expand All</a></li><li style="margin-left:.8em"><a class="bktoc_all_clps" href="#">Collapse All</a></li></ul></div></div><div><h4 class="inline">Suggested citation:</h4><p>McIntosh A, Shaw C, Evans G, Turnbull N, Bahar N, Barclay M, Easton D, Emery J, Gray J, Halpin J, Hopwood P, McKay J, Sheppard C, Sibbering M, Watson W, Wailoo A, Hutchinson A (2004) <i>Clinical Guidelines and Evidence Review for The Classification and Care of Women at Risk of Familial Breast Cancer</i>, London: National Collaborating Centre for Primary Care/University of Sheffield</p></div><div><p>This work is undertaken by ScHARR, University of Sheffield which received funding from the Royal College of General Practitioners on behalf of the National Institute for Clinical Excellence. The views expressed in this Publication are those of the authors and not necessarily those of either the Royal College of General Practitioners or the National Institute for Clinical Excellence.</p></div></div></div>
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<div xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Views</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="PDF_download" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li><a href="/books/NBK65452/?report=reader">PubReader</a></li><li><a href="/books/NBK65452/?report=printable">Print View</a></li><li><a data-jig="ncbidialog" href="#_ncbi_dlg_citbx_NBK65452" data-jigconfig="width:400,modal:true">Cite this Page</a><div id="_ncbi_dlg_citbx_NBK65452" style="display:none" title="Cite this Page"><div class="bk_tt">School of Health and Related Research (ScHARR), University of Sheffield. Clinical Guidelines for the Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care [Internet]. Sheffield (UK): University of Sheffield; 2004 May. (NICE Clinical Guidelines, No. 14.)<span class="bk_cite_avail"></span></div></div></li><li><a href="/books/n/nicecg14/pdf/">PDF version of this title</a> (7.0M)</li><li><a href="#" class="toggle-glossary-link" title="Enable/disable links to the glossary">Disable Glossary Links</a></li></ul></div></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Other titles in this collection</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="source-links" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li><a href="/books/n/nicecollect/">National Institute for Health and Clinical Excellence: Guidance
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</a></li></ul></div></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Related NICE guidance and evidence</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="source-links" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li><a href="/books/n/nicecg41/">NICE Clinical Guideline 41: Familial Breast Cancer: The Classification and Care of Women at Risk of Familial Breast Cancer in Primary, Secondary and Tertiary Care: Update</a></li></ul></div></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Similar articles in PubMed</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="PBooksDiscovery_RA" id="Shutter"></a></div><div class="portlet_content"><ul><li class="brieflinkpopper two_line"><a class="brieflinkpopperctrl" href="/pubmed/10388011" ref="ordinalpos=1&linkpos=1&log$=relatedarticles&logdbfrom=pubmed">Prophylactic Oophorectomy: Reducing the U.S. Death Rate from Epithelial Ovarian Cancer. 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