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It was updated in 2006, 2011 and 2019. See the NICE website for the guideline recommendations and the evidence reviews for the 2019 update. This document PDF preserves evidence reviews and committee discussions for the 2011 guideline. August 2019: The guideline was updated and evidence sections affected and recommendations were removed from this full guideline PDF. November 2016: A footnote was added to PDF recommendations 46, 47, 53, 55, 57 and 58 covering angiotensin-converting enzyme (ACE) inhibitors about 2 MHRA drug safety alerts. These alerts cover ACE inhibitor use during pregnancy and breastfeeding.</strong></p><div class="main-content lit-style"><div class="fm-sec bkr_bottom_sep"><div class="bkr_thumb"><a href="http://www.rcplondon.ac.uk/Pages/index.aspx" title="Royal College of Physicians (UK)" class="img_link icnblk_img" ref="pagearea=logo&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg127-lrg.png" alt="Cover of Hypertension" /></a></div><div class="bkr_bib"><h1 id="_NBK83274_"><span itemprop="name">Hypertension</span></h1><div class="subtitle">The Clinical Management of Primary Hypertension in Adults</div><p><b>Update of Clinical Guidelines 18 and 34</b></p><p><i>NICE Clinical Guidelines, No. 127</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">National Clinical Guideline Centre (UK)</span>.</p><div class="half_rhythm">London: <a href="http://www.rcplondon.ac.uk/Pages/index.aspx" ref="pagearea=meta&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher"><span itemprop="publisher">Royal College of Physicians (UK)</span></a>; <span itemprop="datePublished">2011 Aug</span>.</div><div><a href="/books/about/copyright/">Copyright</a> &#x000a9; 2011, National Clinical Guideline Centre.</div><a class="btn wsprkl bkr_rd" href="/books/n/nicecg127/nicecg127.fm.s1/?report=reader">Read</a></div><div class="bkr_clear"></div></div><div class="bkr_bottom_sep bkr_bottom_margin body-content whole_rhythm"><div itemprop="description"><h2>Excerpt</h2><p>NICE first issued guidance for the management of hypertension in primary care in 2004. This was followed by a rapid update of the pharmacological treatment chapter of the guideline in 2006. The current partial update of the hypertension guideline is in response to the regular five year review cycle of existing NICE guidance. It began with a scoping exercise which identified key areas of the existing guideline for which new evidence had emerged that was likely to influence or change existing guideline recommendations.</p><p>Sections of the guideline that have not been updated continue to stand, however, wherever NICE has subsequently issued new and related guidance relevant to existing recommendations, these have been identified and cross-referred to in this partial update, examples include interventions on lifestyle factors and public health policy recommendations such as smoking cessation, dietary salt restriction, alcohol intake and cardiovascular disease prevention and cardiovascular disease risk assessment. In addition, new NICE guidance developed in areas relevant to hypertension are also highlighted and cross referenced (for example, chronic kidney disease, stroke, diabetes and hypertension in pregnancy).</p><p>The recommendations that have been reviewed in this partial update of the guideline for the clinical management of primary hypertension in adults, include; blood pressure measurement for the diagnosis of hypertension; blood pressure thresholds for intervention with drug therapy and blood pressure targets for treatment; specific aspects of the recommendations for the pharmacological treatment of hypertension; the treatment of hypertension in the very elderly (people aged greater than 80 years); dilemmas surrounding decision making for treatment of hypertension in younger adults (less than 40 years); the treatment of drug resistant hypertension; and wherever appropriate, the impact of age and ethnicity on treatment recommendations.</p></div></div></div><div class="fm-sec"><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> &#x000a9; 2011, National Clinical Guideline Centre.<p class="small">Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.</p><p class="small">The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.</p><p class="small">The rights of National Clinical Guideline Centre to be identified as Author of this work have been asserted by them in accordance with the Copyright, Designs and Patents Act, 1988.</p></div><div class="small"><span class="label">Bookshelf ID: NBK83274</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/22855971" title="PubMed record of this title" ref="pagearea=meta&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">22855971</a></span></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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