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</svg> Books</a></div><div class="jr-rhead f1 flexh"><div class="head"></div><div class="body"><div class="t">Endometrial Cancer Screening (PDQ®): Patient Version</div><div class="j">PDQ Cancer Information Summaries [Internet]</div></div><div class="tail"></div></div><div id="jr-tb2"><a id="jr-bkhelp-sw" class="btn wsprkl hidden" title="Help with NLM PubReader">?</a><a id="jr-help-sw" class="btn wsprkl hidden" title="Settings and typography in NLM PubReader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512" preserveAspectRatio="none"><path d="M462,283.742v-55.485l-29.981-10.662c-11.431-4.065-20.628-12.794-25.274-24.001 c-0.002-0.004-0.004-0.009-0.006-0.013c-4.659-11.235-4.333-23.918,0.889-34.903l13.653-28.724l-39.234-39.234l-28.72,13.652 c-10.979,5.219-23.68,5.546-34.908,0.889c-0.005-0.002-0.01-0.003-0.014-0.005c-11.215-4.65-19.933-13.834-24-25.273L283.741,50 h-55.484l-10.662,29.981c-4.065,11.431-12.794,20.627-24.001,25.274c-0.005,0.002-0.009,0.004-0.014,0.005 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placeholder="search this page" id="jr-fip-term" autocorrect="off" autocomplete="off" /><a id="jr-fip-mg" class="wsprkl btn" title="Find"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 550 600" preserveAspectRatio="none"><path fill="none" stroke="#000" stroke-width="36" stroke-linecap="round" style="fill:#FFF" d="m320,350a153,153 0 1,0-2,2l170,170m-91-117 110,110-26,26-110-110"></path></svg></a><a id="jr-fip-done" class="wsprkl btn" title="Dismiss find">✘</a></nav><nav id="jr-fip-info-p"><a id="jr-fip-prev" class="wsprkl btn" title="Jump to previuos match">◀</a><button id="jr-fip-matches">no matches yet</button><a id="jr-fip-next" class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><div class="fm-sec"><h1 id="_NBK66051_"><span class="title" itemprop="name">Endometrial Cancer Screening (PDQ®)</span></h1><div class="subtitle whole_rhythm">Patient Version</div><p class="contribs">PDQ Screening and Prevention Editorial Board.</p><p class="fm-aai"><a href="#_NBK66051_pubdet_">Publication Details</a></p></div></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><div id="_abs_rndgid_" itemprop="description"><p id="CDR0000258010__112">This PDQ cancer information summary has current information about endometrial cancer screening. It is meant to inform and help patients, families, and caregivers. It does not give formal guidelines or recommendations for making decisions about health care.</p><p id="CDR0000258010__113">Editorial Boards write the PDQ cancer information summaries and keep them up to date. These Boards are made up of experts in cancer treatment and other specialties related to cancer. The summaries are reviewed regularly and changes are made when there is new information. The date on each summary ("Date Last Modified") is the date of the most recent change. The information in this patient summary was taken from the health professional version, which is reviewed regularly and updated as needed, by the PDQ Screening and Prevention Editorial Board.</p></div><div id="CDR0000258010__1"><h2 id="_CDR0000258010__1_">What Is Screening?</h2><p id="CDR0000258010__2"><a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046171/" class="def">Screening</a> is looking for <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045333/" class="def">cancer</a> before a person has any <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045022/" class="def">symptoms</a>. This can help find
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cancer at an early <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045885/" class="def">stage</a>. When <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044636/" class="def">abnormal</a>
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<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046683/" class="def">tissue</a> or cancer is found early, it may
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be easier to treat. By the time symptoms appear, cancer may have begun
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to spread.</p><p id="CDR0000258010__3"><a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044724/" class="def">Scientists</a> are trying to better understand which
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people are more likely to get certain types of cancer. They also study the things
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we do and the things around us to see if they cause cancer. This
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information helps doctors recommend who should be screened for cancer, which
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screening tests should be used, and how often the tests should be done.</p><p id="CDR0000258010__4">It is important to remember that your doctor does not necessarily
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think you have cancer if he or she suggests a screening test. Screening
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tests are given when you have no cancer symptoms.</p><p id="CDR0000258010__92">If a screening test result is abnormal, you may need to have more tests done to find out if you have cancer. These are called <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045959/" class="def">diagnostic tests</a>.
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</p></div><div id="CDR0000258010__5"><h2 id="_CDR0000258010__5_">General Information About Endometrial Cancer</h2><div id="CDR0000258010__5.kp" class="box boxed-text-box whole_rhythm hide-overflow"><h4><span class="title">Key Points for This Section</span></h4><ul><li class="half_rhythm"><div><a href="#CDR0000258010__6">Endometrial cancer is a disease in which malignant (cancer)
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cells form in the tissues of the endometrium.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__10">Endometrial cancer is most common in postmenopausal women.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__14"> Health history and certain medicines can affect the risk of
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developing endometrial cancer.</a></div></li></ul></div><div id="CDR0000258010__6"><h3>Endometrial cancer is a disease in which malignant (cancer)
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cells form in the tissues of the endometrium.</h3><p id="CDR0000258010__8">The <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046108/" class="def">endometrium</a> is the
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innermost lining of the <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046645/" class="def">uterus</a>. The uterus is
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a hollow, muscular <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000257523/" class="def">organ</a> in a
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woman's <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046246/" class="def">pelvis</a>. The uterus is where a <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046400/" class="def">fetus</a> grows. In most nonpregnant
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women, the uterus is about 3 inches long.</p><div id="CDR0000258010__109" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Anatomy%20of%20the%20female%20reproductive%20system&p=BOOKS&id=610167_CDR0000609921.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img src="/books/NBK66051/bin/CDR0000609921.jpg" alt="Anatomy of the female reproductive system; drawing shows the uterus, myometrium (muscular outer layer of the uterus), endometrium (inner lining of the uterus), ovaries, fallopian tubes, cervix, and vagina." class="tileshop" title="Click on image to zoom" /></a></div><div class="caption"><p>Anatomy of the female reproductive system. The organs in the female reproductive system include the uterus, ovaries, fallopian tubes, cervix, and vagina. The uterus has a muscular outer layer called the myometrium and an inner lining called the endometrium. </p></div></div><p id="CDR0000258010__9"><a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045333/" class="def">Cancer</a> of the endometrium
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is different from cancer of the muscle of the uterus, which is called
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<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000445097/" class="def">uterine sarcoma</a>. For more information, see <a href="/books/n/pdqcis/CDR0000257805/?report=reader">Uterine Sarcoma
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Treatment</a>.</p><p id="CDR0000258010__106">Other PDQ summaries containing information related to <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000444987/" class="def">endometrial cancer</a> include:</p><ul id="CDR0000258010__107"><li class="half_rhythm"><div>
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<a href="/books/n/pdqcis/CDR0000062964/?report=reader">Endometrial Cancer Treatment</a>
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</div></li><li class="half_rhythm"><div>
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<a href="/books/n/pdqcis/CDR0000258009/?report=reader">Endometrial Cancer Prevention</a>
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</div></li></ul></div><div id="CDR0000258010__10"><h3>Endometrial cancer is most common in postmenopausal women.</h3><p id="CDR0000258010__111">Endometrial cancer is <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046450/" class="def">diagnosed</a> most often in <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045269/" class="def">postmenopausal</a> women at an average age of 60 years.</p><p id="CDR0000258010__12">Over the last 10 years, the number of new cases of endometrial cancer in White women has increased by about 1% per year, and the number of new cases in women of all other racial and ethnic groups has increased by 2%‒3% per year. Since the mid-2000s, death rates from endometrial cancer have increased by just under 2% per year.</p></div><div id="CDR0000258010__14"><h3> Health history and certain medicines can affect the risk of
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developing endometrial cancer.</h3><p id="CDR0000258010__16">Anything that increases your chance of getting a disease
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is called a <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045873/" class="def">risk factor</a>. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. People who think they may be at risk should discuss this with their doctor. Risk factors for endometrial cancer include the
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following:</p><ul id="CDR0000258010__17"><li class="half_rhythm"><div>Taking <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000509341/" class="def">tamoxifen</a>
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for treatment or <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000439419/" class="def">prevention</a> of <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000444971/" class="def">breast cancer</a>.</div></li><li class="half_rhythm"><div>Taking <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046076/" class="def">estrogen</a> alone. (Taking estrogen in combination with
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<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000304743/" class="def">progestin</a> does
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not appear to increase the risk of endometrial cancer.)</div></li><li class="half_rhythm"><div>Being <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000304742/" class="def">overweight</a>.</div></li><li class="half_rhythm"><div>Eating a high-fat <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044660/" class="def">diet</a>.</div></li><li class="half_rhythm"><div> Never giving birth.</div></li><li class="half_rhythm"><div>Beginning <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046297/" class="def">menstruation</a> at an early age.</div></li><li class="half_rhythm"><div>Reaching <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046296/" class="def">menopause</a> at an older age.</div></li><li class="half_rhythm"><div>Having the <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045693/" class="def">gene</a> for <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044884/" class="def">hereditary nonpolyposis colon cancer</a> (HNPCC). </div></li><li class="half_rhythm"><div>Being a White individual.</div></li></ul></div></div><div id="CDR0000258010__13"><h2 id="_CDR0000258010__13_">Endometrial Cancer Screening</h2><div id="CDR0000258010__13.kp" class="box boxed-text-box whole_rhythm hide-overflow"><h4><span class="title">Key Points for This Section</span></h4><ul><li class="half_rhythm"><div><a href="#CDR0000258010__52"> Tests are used to screen for different types of cancer when a person does not have symptoms.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__100">Endometrial cancer is usually found early.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__69">There is no standard or routine screening test for endometrial cancer.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__18"> Tests that may detect (find) endometrial cancer are being studied:</a></div><ul><li class="half_rhythm"><div><a href="#CDR0000258010__20">Pap test</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__26">Transvaginal ultrasound</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__94">Endometrial sampling</a></div></li></ul></li><li class="half_rhythm"><div><a href="#CDR0000258010__114">Screening tests for endometrial cancer are being studied in clinical trials.</a></div></li></ul></div><div id="CDR0000258010__52"><h3> Tests are used to screen for different types of cancer when a person does not have symptoms.</h3><p id="CDR0000258010__55"><a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044724/" class="def">Scientists</a> study <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046171/" class="def">screening</a> tests to find those with the fewest harms and most benefits. <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045333/" class="def">Cancer</a> screening trials also are meant to show whether early detection (finding cancer before it causes <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045022/" class="def">symptoms</a>) helps a person live longer or decreases a person's chance of dying from the disease. For some types of cancer, the chance of <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000454708/" class="def">recovery</a> is better if the disease is found and treated at an early <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045885/" class="def">stage</a>.</p></div><div id="CDR0000258010__100"><h3>Endometrial cancer is usually found early.</h3><p id="CDR0000258010__102">
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<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000444987/" class="def">Endometrial cancer</a> usually causes symptoms (such as <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044308/" class="def">vaginal</a> bleeding) and is found at an early stage, when there is a good chance of recovery. </p></div><div id="CDR0000258010__69"><h3>There is no standard or routine screening test for endometrial cancer.</h3><p id="CDR0000258010__71">Screening for endometrial cancer is under study and there are screening clinical trials taking place in many parts of the country.
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Information about ongoing clinical trials is available from the <a href="https://www.cancer.gov/research/participate/clinical-trials" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NCI website</a>.</p></div><div id="CDR0000258010__18"><h3> Tests that may detect (find) endometrial cancer are being studied:</h3><div id="CDR0000258010__20"><h4>Pap test</h4><p id="CDR0000258010__48">A <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045978/" class="def">Pap test</a> is a procedure to collect <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046476/" class="def">cells</a> from the surface of the <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046133/" class="def">cervix</a> and <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046646/" class="def">vagina</a>. A piece of cotton, a brush, or a small wooden stick is used to gently scrape cells from the cervix and vagina. The cells are viewed under a <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000638184/" class="def">microscope</a> to find out if they are <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044636/" class="def">abnormal</a>. This procedure is also called a Pap smear.</p><p id="CDR0000258010__22"> Pap tests are not used to screen for endometrial cancer; however, Pap test results sometimes show signs of an abnormal <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046108/" class="def">endometrium</a> (lining of the <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046645/" class="def">uterus</a>). <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044671/" class="def">Follow-up</a> tests may
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detect endometrial cancer.</p></div><div id="CDR0000258010__26"><h4>Transvaginal ultrasound</h4><p id="CDR0000258010__103">No studies have shown that screening by <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046633/" class="def">transvaginal ultrasound</a> (TVU) lowers the number of deaths caused by endometrial cancer.</p><p id="CDR0000258010__49">Transvaginal ultrasound (TVU) is a procedure used to examine the vagina, uterus, <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045687/" class="def">fallopian tubes</a>, and <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046501/" class="def">bladder</a>. It is also called endovaginal ultrasound. An <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000367430/" class="def">ultrasound transducer</a> (probe) is inserted into the vagina and used to bounce high-energy sound waves (ultrasound) off internal <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046683/" class="def">tissues</a> or <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000257523/" class="def">organs</a> and make echoes. The echoes form a picture of body tissues called a <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046587/" class="def">sonogram</a>. The
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doctor can identify <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046634/" class="def">tumors</a> by looking at the sonogram.</p><div id="CDR0000258010__110" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Transvaginal%20ultrasound&p=BOOKS&id=610167_CDR0000618018.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img src="/books/NBK66051/bin/CDR0000618018.jpg" alt="Transvaginal ultrasound; drawing shows a side view of the female reproductive anatomy during a transvaginal ultrasound procedure. An ultrasound probe (a device that makes sound waves that bounce off tissues inside the body) is shown inserted into the vagina. The bladder, uterus, right fallopian tube, and right ovary are also shown. The inset shows the diagnostic sonographer (a person trained to perform ultrasound procedures) examining a woman on a table, and a computer screen shows an image of the patient’s internal tissues." class="tileshop" title="Click on image to zoom" /></a></div><div class="caption"><p>Transvaginal ultrasound. An ultrasound probe connected to a computer is inserted into the vagina and is gently moved to show different organs. The probe bounces sound waves off internal organs and tissues to make echoes that form a sonogram (computer picture).</p></div></div><p id="CDR0000258010__105">TVU is commonly
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|
used to examine women who have abnormal vaginal bleeding. For women who have or are at risk for <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044884/" class="def">hereditary nonpolyposis colon cancer</a>, experts suggest yearly screening with transvaginal ultrasound, beginning as early as age 25.</p><p id="CDR0000258010__108">The use of <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000509341/" class="def">tamoxifen</a> to treat or prevent <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000444971/" class="def">breast cancer</a> increases the risk of endometrial cancer. TVU is not useful in screening for endometrial cancer in women who take tamoxifen but do not have any symptoms of endometrial cancer. In women taking tamoxifen, TVU should be used in those who have vaginal bleeding.</p></div><div id="CDR0000258010__94"><h4>Endometrial sampling</h4><p id="CDR0000258010__104">It has not been proven that screening by endometrial sampling (<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045164/" class="def">biopsy</a>) lowers the number of deaths caused by endometrial cancer.</p><p id="CDR0000258010__96">Endometrial sampling is the removal of tissue from the endometrium
|
|
by inserting a brush, <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046460/" class="def">curette</a>, or thin, flexible tube through the cervix and into the uterus. The tool is used to gently scrape a small amount of tissue from the endometrium and then remove the tissue samples. A <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046244/" class="def">pathologist</a> views the tissue under a microscope to look for cancer cells.</p><p id="CDR0000258010__74">Endometrial sampling is commonly
|
|
used to examine women who have abnormal vaginal bleeding. If you have abnormal vaginal bleeding, check with your doctor.</p></div></div><div id="CDR0000258010__114"><h3>Screening tests for endometrial cancer are being studied in clinical trials.</h3><p id="CDR0000258010__114_md_95">Information about <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045961/" class="def">clinical trials</a> supported by <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044267/" class="def">NCI</a> can be found on NCI’s <a href="https://www.cancer.gov/research/participate/clinical-trials-search" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">clinical trials search</a> webpage. Clinical trials supported by other organizations can be found on the <a href="https://clinicaltrials.gov/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">ClinicalTrials.gov</a> website.</p></div></div><div id="CDR0000258010__34"><h2 id="_CDR0000258010__34_">Risks of Endometrial Cancer Screening</h2><div id="CDR0000258010__34.kp" class="box boxed-text-box whole_rhythm hide-overflow"><h4><span class="title">Key Points for This Section</span></h4><ul><li class="half_rhythm"><div><a href="#CDR0000258010__35">Screening tests have risks.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__38">The risks of endometrial cancer screening tests include the
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following:</a></div><ul><li class="half_rhythm"><div><a href="#CDR0000258010__65">Finding endometrial cancer may not improve health or help a woman live
|
|
longer.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__43">False-negative test results can occur.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__40">False-positive test results can occur.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__78">Side effects may be caused by the test itself.</a></div></li></ul></li></ul></div><div id="CDR0000258010__35"><h3>Screening tests have risks.</h3><p id="CDR0000258010__37">Decisions about <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046171/" class="def">screening</a> tests can be difficult. Not all screening tests are helpful and most have risks. Before having any screening test, you may
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want to discuss the test with your doctor. It is important to know the risks of
|
|
the test and whether it has been proven to reduce the risk of dying from
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<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045333/" class="def">cancer</a>.</p></div><div id="CDR0000258010__38"><h3>The risks of endometrial cancer screening tests include the
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following:</h3><div id="CDR0000258010__65"><h4>Finding endometrial cancer may not improve health or help a woman live
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longer.</h4><p id="CDR0000258010__67"> Screening
|
|
may not improve your health or help you live longer if you have <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000478743/" class="def">advanced</a>
|
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<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000444987/" class="def">endometrial cancer</a> or if it has already spread to
|
|
other places in your body.</p><p id="CDR0000258010__91"> Some cancers never cause <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045022/" class="def">symptoms</a>
|
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or become life-threatening, but if found by a screening
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test, the cancer may be treated. It is not known if treatment of these cancers would help you live longer than if no treatment were given, and treatments for cancer may have serious <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046580/" class="def">side effects</a>.</p></div><div id="CDR0000258010__43"><h4>False-negative test results can occur.</h4><p id="CDR0000258010__45">Screening test results may appear to be normal even though endometrial cancer is
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present. A woman who receives a <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000340928/" class="def">false-negative test result</a> (one that
|
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shows there is no cancer when there really is) may delay seeking medical care even if she has symptoms.</p></div><div id="CDR0000258010__40"><h4>False-positive test results can occur.</h4><p id="CDR0000258010__57">Screening test results may appear to be <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000044636/" class="def">abnormal</a> even though no
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cancer is present. A <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000340929/" class="def">false-positive test result</a> (one that shows there is cancer when there really isn't) can cause <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000430405/" class="def">anxiety</a> and is usually followed by more tests (such as
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<a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045164/" class="def">biopsy</a>), which also have risks. </p></div><div id="CDR0000258010__78"><h4>Side effects may be caused by the test itself.</h4><p id="CDR0000258010__90">Side effects that may be caused by screening tests for endometrial cancer include: </p><ul id="CDR0000258010__85"><li class="half_rhythm"><div>Discomfort.</div></li><li class="half_rhythm"><div>Bleeding.</div></li><li class="half_rhythm"><div><a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000045364/" class="def">Infection</a>.</div></li><li class="half_rhythm"><div>Puncture of the <a href="/books/n/pdqcis/glossary/def-item/glossary_CDR0000046645/" class="def">uterus</a> (rare).</div></li></ul><p id="CDR0000258010__89"><div class="milestone-start" id="CDR0000258010__87"></div>If you have any questions about your risk for endometrial cancer or the need for screening tests, check with your doctor.<div class="milestone-end"></div></p></div></div></div><div id="CDR0000258010__AboutThis_1"><h2 id="_CDR0000258010__AboutThis_1_">About This PDQ Summary</h2><div id="CDR0000258010__AboutThis_2"><h3>About PDQ</h3><p id="CDR0000258010__AboutThis_3">Physician Data Query (PDQ) is the National Cancer Institute's (NCI's) comprehensive cancer information database. The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries come in two versions. The health professional versions have detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions have cancer information that is accurate and up to date and most versions are also available in <a href="https://www.cancer.gov/espanol/publicaciones/pdq" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Spanish</a>.</p><p id="CDR0000258010__AboutThis_4">PDQ is a service of the NCI. The NCI is part of the National Institutes of Health (NIH). NIH is the federal government’s center of biomedical research. The PDQ summaries are based on an independent review of the medical literature. They are not policy statements of the NCI or the NIH.</p></div><div id="CDR0000258010__AboutThis_5"><h3>Purpose of This Summary</h3><p id="CDR0000258010__AboutThis_6">This PDQ cancer information summary has current information about endometrial cancer screening. It is meant to inform and help patients, families, and caregivers. It does not give formal guidelines or recommendations for making decisions about health care.</p></div><div id="CDR0000258010__AboutThis_7"><h3>Reviewers and Updates</h3><p id="CDR0000258010__AboutThis_8">Editorial Boards write the PDQ cancer information summaries and keep them up to date. These Boards are made up of experts in cancer treatment and other specialties related to cancer. The summaries are reviewed regularly and changes are made when there is new information. The date on each summary ("Updated") is the date of the most recent change.
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</p><p id="CDR0000258010__AboutThis_9">The information in this patient summary was taken from the health professional version, which is reviewed regularly and updated as needed, by the <a href="https://www.cancer.gov/publications/pdq/editorial-boards/screening-prevention" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">PDQ Screening and Prevention Editorial Board</a>.
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</p></div><div id="CDR0000258010__AboutThis_10"><h3>Clinical Trial Information</h3><p id="CDR0000258010__AboutThis_11">A clinical trial is a study to answer a scientific question, such as whether one treatment is better than another. Trials are based on past studies and what has been learned in the laboratory. Each trial answers certain scientific questions in order to find new and better ways to help cancer patients. During treatment clinical trials, information is collected about the effects of a new treatment and how well it works. If a clinical trial shows that a new treatment is better than one currently being used, the new treatment may become "standard." Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment.
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</p><p id="CDR0000258010__AboutThis_12">Clinical trials can be found online at <a href="https://www.cancer.gov/research/participate/clinical-trials" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NCI's website</a>. For more information, call the <a href="https://www.cancer.gov/contact/contact-center" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Cancer Information Service</a> (CIS), NCI's contact center, at 1-800-4-CANCER (1-800-422-6237).
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</p></div><div id="CDR0000258010__AboutThis_13"><h3>Permission to Use This Summary</h3><p id="CDR0000258010__AboutThis_14">PDQ is a registered trademark. The content of PDQ documents can be used freely as text. It cannot be identified as an NCI PDQ cancer information summary unless the whole summary is shown and it is updated regularly. However, a user would be allowed to write a sentence such as “NCI’s PDQ cancer information summary about breast cancer prevention states the risks in the following way: [include excerpt from the summary].”
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</p><p id="CDR0000258010__AboutThis_15">The best way to cite this PDQ summary is:</p><p id="CDR0000258010__AboutThis_21">PDQ® Screening and Prevention Editorial Board. PDQ Endometrial Cancer Screening. Bethesda, MD: National Cancer Institute. Updated <MM/DD/YYYY>. Available at: <a href="https://www.cancer.gov/types/uterine/patient/endometrial-screening-pdq" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www.cancer.gov/types/uterine/patient/endometrial-screening-pdq</a>. Accessed <MM/DD/YYYY>. [PMID: 26389486]</p><p id="CDR0000258010__AboutThis_16">Images in this summary are used with permission of the author(s), artist, and/or publisher for use in the PDQ summaries only. If you want to use an image from a PDQ summary and you are not using the whole summary, you must get permission from the owner. It cannot be given by the National Cancer Institute. Information about using the images in this summary, along with many other images related to cancer can be found in <a href="https://visualsonline.cancer.gov/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Visuals Online</a>. Visuals Online is a collection of more than 3,000 scientific images.
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</p></div><div id="CDR0000258010__AboutThis_17"><h3>Disclaimer</h3><p id="CDR0000258010__AboutThis_18">The information in these summaries should not be used to make decisions about insurance reimbursement. More information on insurance coverage is available on Cancer.gov on the <a href="https://www.cancer.gov/about-cancer/managing-care" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Managing Cancer Care</a> page.</p></div><div id="CDR0000258010__AboutThis_19"><h3>Contact Us</h3><p id="CDR0000258010__AboutThis_20">More information about contacting us or receiving help with the Cancer.gov website can be found on our <a href="https://www.cancer.gov/contact" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Contact Us for Help</a> page. Questions can also be submitted to Cancer.gov through the website’s <a href="https://www.cancer.gov/contact/email-us" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">E-mail Us</a>.</p></div></div></div></div><div class="fm-sec"><h2 id="_NBK66051_pubdet_">Publication Details</h2><h3>Author Information and Affiliations</h3><p class="contrib-group"><h4>Authors</h4><span itemprop="author">PDQ Screening and Prevention Editorial Board</span>.</p><h3>Publication History</h3><p class="small">Published online: December 5, 2024.</p><h3>Version History</h3><ul class="simple-list" style="padding:0"><li><span class="bk_col_itm">NBK66051.10</span> December 5, 2024 (Displayed Version)</li><li><span class="bk_col_itm"><a href="/books/NBK66051.9/?report=reader">NBK66051.9</a></span> June 26, 2023</li><li><span class="bk_col_itm"><a href="/books/NBK66051.8/?report=reader">NBK66051.8</a></span> August 5, 2021</li><li><span class="bk_col_itm"><a href="/books/NBK66051.7/?report=reader">NBK66051.7</a></span> April 14, 2021</li><li><span class="bk_col_itm"><a href="/books/NBK66051.6/?report=reader">NBK66051.6</a></span> March 18, 2020</li><li><span class="bk_col_itm"><a href="/books/NBK66051.5/?report=reader">NBK66051.5</a></span> May 2, 2019</li><li><span class="bk_col_itm"><a href="/books/NBK66051.4/?report=reader">NBK66051.4</a></span> March 15, 2019</li><li><span class="bk_col_itm"><a href="/books/NBK66051.3/?report=reader">NBK66051.3</a></span> April 6, 2018</li><li><span class="bk_col_itm"><a href="/books/NBK66051.2/?report=reader">NBK66051.2</a></span> April 7, 2017</li><li><span class="bk_col_itm"><a href="/books/NBK66051.1/?report=reader">NBK66051.1</a></span> July 23, 2015</li></ul><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright Notice</a></div></div><h3>Publisher</h3><p><a href="http://www.cancer.gov/" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">National Cancer Institute (US)</a>, Bethesda (MD)</p><h3>NLM Citation</h3><p>PDQ Screening and Prevention Editorial Board. Endometrial Cancer Screening (PDQ®): Patient Version. 2024 Dec 5. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. <span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article><article data-type="boxed-text" id="figobCDR00002580105kp"><div id="CDR0000258010__5.kp" class="box boxed-text-box whole_rhythm hide-overflow"><h4><span class="title">Key Points for This Section</span></h4><ul><li class="half_rhythm"><div><a href="#CDR0000258010__6">Endometrial cancer is a disease in which malignant (cancer)
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cells form in the tissues of the endometrium.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__10">Endometrial cancer is most common in postmenopausal women.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__14"> Health history and certain medicines can affect the risk of
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developing endometrial cancer.</a></div></li></ul></div></article><article data-type="fig" id="figobCDR0000258010109"><div id="CDR0000258010__109" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Anatomy%20of%20the%20female%20reproductive%20system&p=BOOKS&id=610167_CDR0000609921.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK66051/bin/CDR0000609921.jpg" alt="Anatomy of the female reproductive system; drawing shows the uterus, myometrium (muscular outer layer of the uterus), endometrium (inner lining of the uterus), ovaries, fallopian tubes, cervix, and vagina." class="tileshop" title="Click on image to zoom" /></a></div><div class="caption"><p>Anatomy of the female reproductive system. The organs in the female reproductive system include the uterus, ovaries, fallopian tubes, cervix, and vagina. The uterus has a muscular outer layer called the myometrium and an inner lining called the endometrium. </p></div></div></article><article data-type="boxed-text" id="figobCDR000025801013kp"><div id="CDR0000258010__13.kp" class="box boxed-text-box whole_rhythm hide-overflow"><h4><span class="title">Key Points for This Section</span></h4><ul><li class="half_rhythm"><div><a href="#CDR0000258010__52"> Tests are used to screen for different types of cancer when a person does not have symptoms.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__100">Endometrial cancer is usually found early.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__69">There is no standard or routine screening test for endometrial cancer.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__18"> Tests that may detect (find) endometrial cancer are being studied:</a></div><ul><li class="half_rhythm"><div><a href="#CDR0000258010__20">Pap test</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__26">Transvaginal ultrasound</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__94">Endometrial sampling</a></div></li></ul></li><li class="half_rhythm"><div><a href="#CDR0000258010__114">Screening tests for endometrial cancer are being studied in clinical trials.</a></div></li></ul></div></article><article data-type="fig" id="figobCDR0000258010110"><div id="CDR0000258010__110" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Transvaginal%20ultrasound&p=BOOKS&id=610167_CDR0000618018.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK66051/bin/CDR0000618018.jpg" alt="Transvaginal ultrasound; drawing shows a side view of the female reproductive anatomy during a transvaginal ultrasound procedure. An ultrasound probe (a device that makes sound waves that bounce off tissues inside the body) is shown inserted into the vagina. The bladder, uterus, right fallopian tube, and right ovary are also shown. The inset shows the diagnostic sonographer (a person trained to perform ultrasound procedures) examining a woman on a table, and a computer screen shows an image of the patient’s internal tissues." class="tileshop" title="Click on image to zoom" /></a></div><div class="caption"><p>Transvaginal ultrasound. An ultrasound probe connected to a computer is inserted into the vagina and is gently moved to show different organs. The probe bounces sound waves off internal organs and tissues to make echoes that form a sonogram (computer picture).</p></div></div></article><article data-type="boxed-text" id="figobCDR000025801034kp"><div id="CDR0000258010__34.kp" class="box boxed-text-box whole_rhythm hide-overflow"><h4><span class="title">Key Points for This Section</span></h4><ul><li class="half_rhythm"><div><a href="#CDR0000258010__35">Screening tests have risks.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__38">The risks of endometrial cancer screening tests include the
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following:</a></div><ul><li class="half_rhythm"><div><a href="#CDR0000258010__65">Finding endometrial cancer may not improve health or help a woman live
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longer.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__43">False-negative test results can occur.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__40">False-positive test results can occur.</a></div></li><li class="half_rhythm"><div><a href="#CDR0000258010__78">Side effects may be caused by the test itself.</a></div></li></ul></li></ul></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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