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<meta name="robots" content="INDEX,FOLLOW,NOARCHIVE,NOIMAGEINDEX" /><meta name="author" content="National Clinical Guideline Centre (UK)" /><meta name="citation_title" content="Nocturnal Enuresis" /><meta name="citation_publisher" content="Royal College of Physicians (UK)" /><meta name="citation_date" content="2010" /><meta name="citation_author" content="National Clinical Guideline Centre (UK)" /><meta name="citation_pmid" content="22031959" /><meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK62712/" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Nocturnal Enuresis" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="Royal College of Physicians (UK)" /><meta name="DC.Contributor" content="National Clinical Guideline Centre (UK)" /><meta name="DC.Date" content="2010" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK62712/" /><meta name="DC.Language" content="en" /><meta name="description" content="This guideline aims to provide advice on the assessment and management of children and young people with bedwetting. The guidance is applicable to children and young people up to 19 years with the symptom of bedwetting. It has been common practice to define enuresis as abnormal from 5 years and only to consider children for treatment when they are 7 years. While the prevalence of symptoms decreases with age the guideline scope did not specify a younger age limit in order to consider whether there were useful interventions that might be of benefit to children previously excluded from advice and services." /><meta name="og:title" content="Nocturnal Enuresis" /><meta name="og:type" content="book" /><meta name="og:description" content="This guideline aims to provide advice on the assessment and management of children and young people with bedwetting. The guidance is applicable to children and young people up to 19 years with the symptom of bedwetting. It has been common practice to define enuresis as abnormal from 5 years and only to consider children for treatment when they are 7 years. While the prevalence of symptoms decreases with age the guideline scope did not specify a younger age limit in order to consider whether there were useful interventions that might be of benefit to children previously excluded from advice and services." /><meta name="og:url" content="https://www.ncbi.nlm.nih.gov/books/NBK62712/" /><meta name="og:site_name" content="NCBI Bookshelf" /><meta name="og:image" content="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg111-lrg.png" /><meta name="twitter:card" content="summary" /><meta name="twitter:site" content="@ncbibooks" /><meta name="bk-non-canon-loc" content="/books/n/nicecg111/toc/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK62712/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" /><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript">window.name="mainwindow";</script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/Book"><div class="meta-content fm-sec"><div class="iconblock whole_rhythm clearfix no_top_margin"><a href="http://www.rcplondon.ac.uk/Pages/index.aspx" title="Royal College of Physicians (UK)" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg111-lrg.png" alt="Cover of Nocturnal Enuresis" /></a><div class="icnblk_cntnt"><h1 id="_NBK62712_"><span itemprop="name">Nocturnal Enuresis</span></h1><div class="subtitle">The Management of Bedwetting in Children and Young People</div><p><i>NICE Clinical Guidelines, No. 111</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">National Clinical Guideline Centre (UK)</span>.</p><div class="half_rhythm">London: <a href="http://www.rcplondon.ac.uk/Pages/index.aspx" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">Royal College of Physicians (UK)</span></a>; <span itemprop="datePublished">2010</span>.</div><div><a href="/books/about/copyright/">Copyright</a> © 2010, National Clinical Guideline Centre.</div></div></div></div><div class="body-content whole_rhythm" itemprop="text"><div itemprop="description"><h2>Excerpt</h2><p>This guideline aims to provide advice on the assessment and management of children and young people with bedwetting. The guidance is applicable to children and young people up to 19 years with the symptom of bedwetting. It has been common practice to define enuresis as abnormal from 5 years and only to consider children for treatment when they are 7 years. While the prevalence of symptoms decreases with age the guideline scope did not specify a younger age limit in order to consider whether there were useful interventions that might be of benefit to children previously excluded from advice and services.</p></div><div><h2>Contents</h2><ul id="toc_tllNBK62712_nicecg111_fm_s1" class="simple-list toc toc-toggle"><li class="half_rhythm" id="toc_itm_NBK62712_nicecg111_fm_s1"><a href="/books/n/nicecg111/nicecg111.fm.s1/" class="toc-item">Patient-Centered Care</a></li><li class="half_rhythm" id="toc_itm_NBK62712_nicecg111_fm_s2"><a href="/books/n/nicecg111/nicecg111.fm.s2/" class="toc-item">Key priorities for implementation</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1"><a href="/books/n/nicecg111/ch1/" class="toc-item">1. Guidance</a><ul id="toc_lst_NBK62712_ch1_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s1"><a href="/books/n/nicecg111/ch1/#ch1.s1" class="toc-item">1.1 Principles of care</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s2"><a href="/books/n/nicecg111/ch1/#ch1.s2" class="toc-item">1.2 Information for the child or young person and family</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s3"><a href="/books/n/nicecg111/ch1/#ch1.s3" class="toc-item">1.3 Assessment and investigation</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s4"><a href="/books/n/nicecg111/ch1/#ch1.s4" class="toc-item">1.4 Planning management</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s5"><a href="/books/n/nicecg111/ch1/#ch1.s5" class="toc-item">1.5 Advice on fluid intake, diet and toileting patterns</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s6"><a href="/books/n/nicecg111/ch1/#ch1.s6" class="toc-item">1.6 Lifting and waking</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s7"><a href="/books/n/nicecg111/ch1/#ch1.s7" class="toc-item">1.7 Reward systems</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s8"><a href="/books/n/nicecg111/ch1/#ch1.s8" class="toc-item">1.8 Initial treatment – alarms</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s10"><a href="/books/n/nicecg111/ch1/#ch1.s10" class="toc-item">1.9 Lack of response to alarm treatment</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s11"><a href="/books/n/nicecg111/ch1/#ch1.s11" class="toc-item">1.10 Initial treatment – desmopressin</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s12"><a href="/books/n/nicecg111/ch1/#ch1.s12" class="toc-item">1.11 Children and young people experiencing recurrence of bedwetting</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s13"><a href="/books/n/nicecg111/ch1/#ch1.s13" class="toc-item">1.12 Lack of response to initial treatment options</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s14"><a href="/books/n/nicecg111/ch1/#ch1.s14" class="toc-item">1.13 Anticholinergics</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s15"><a href="/books/n/nicecg111/ch1/#ch1.s15" class="toc-item">1.14 Tricyclics</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s16"><a href="/books/n/nicecg111/ch1/#ch1.s16" class="toc-item">1.15 Training programmes for the management of bedwetting</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch1_s17"><a href="/books/n/nicecg111/ch1/#ch1.s17" class="toc-item">1.16 Children under 5 years with bedwetting</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2"><a href="/books/n/nicecg111/ch2/" class="toc-item">2. Introduction</a><ul id="toc_lst_NBK62712_ch2_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s1"><a href="/books/n/nicecg111/ch2/#ch2.s1" class="toc-item">2.1 Nocturnal Enuresis and Bedwetting</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s6"><a href="/books/n/nicecg111/ch2/#ch2.s6" class="toc-item">2.2 Approach of this Guideline</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s7"><a href="/books/n/nicecg111/ch2/#ch2.s7" class="toc-item">2.3 Remit</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s8"><a href="/books/n/nicecg111/ch2/#ch2.s8" class="toc-item">2.4 What is a guideline?</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s9"><a href="/books/n/nicecg111/ch2/#ch2.s9" class="toc-item">2.5 What the guideline covers</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s12"><a href="/books/n/nicecg111/ch2/#ch2.s12" class="toc-item">2.6 What the guideline does not cover</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s14"><a href="/books/n/nicecg111/ch2/#ch2.s14" class="toc-item">2.7 Guideline Limitations</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s15"><a href="/books/n/nicecg111/ch2/#ch2.s15" class="toc-item">2.8 Who developed this guideline?</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s23"><a href="/books/n/nicecg111/ch2/#ch2.s23" class="toc-item">2.9 Research recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s39"><a href="/books/n/nicecg111/ch2/#ch2.s39" class="toc-item">2.10 Acknowledgements</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch2_s40"><a href="/books/n/nicecg111/ch2/#ch2.s40" class="toc-item">2.11 Glossary</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3"><a href="/books/n/nicecg111/ch3/" class="toc-item">3. Methods</a><ul id="toc_lst_NBK62712_ch3_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s1"><a href="/books/n/nicecg111/ch3/#ch3.s1" class="toc-item">3.1 Guideline methodology</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s2"><a href="/books/n/nicecg111/ch3/#ch3.s2" class="toc-item">3.2 Process of guideline development</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s3"><a href="/books/n/nicecg111/ch3/#ch3.s3" class="toc-item">3.3 Developing the clinical questions</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s4"><a href="/books/n/nicecg111/ch3/#ch3.s4" class="toc-item">3.4 Outcomes</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s7"><a href="/books/n/nicecg111/ch3/#ch3.s7" class="toc-item">3.5 Choice of subgroups</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s8"><a href="/books/n/nicecg111/ch3/#ch3.s8" class="toc-item">3.6 Literature search strategy</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s11"><a href="/books/n/nicecg111/ch3/#ch3.s11" class="toc-item">3.7 Assessing quality of evidence</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s14"><a href="/books/n/nicecg111/ch3/#ch3.s14" class="toc-item">3.8 GRADE (Grading of Recommendations, Assessment, Development and Evaluation)</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s21"><a href="/books/n/nicecg111/ch3/#ch3.s21" class="toc-item">3.9 Evidence reviewing process</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s33"><a href="/books/n/nicecg111/ch3/#ch3.s33" class="toc-item">3.10 Health Economics methods</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s36"><a href="/books/n/nicecg111/ch3/#ch3.s36" class="toc-item">3.11 Development of the recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s37"><a href="/books/n/nicecg111/ch3/#ch3.s37" class="toc-item">3.12 Areas without evidence and consensus methodology</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s38"><a href="/books/n/nicecg111/ch3/#ch3.s38" class="toc-item">3.13 Update</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s39"><a href="/books/n/nicecg111/ch3/#ch3.s39" class="toc-item">3.14 Consultation</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s40"><a href="/books/n/nicecg111/ch3/#ch3.s40" class="toc-item">3.15 Related NICE Guidance</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s41"><a href="/books/n/nicecg111/ch3/#ch3.s41" class="toc-item">3.16 Disclaimer</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch3_s42"><a href="/books/n/nicecg111/ch3/#ch3.s42" class="toc-item">3.17 Funding</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch4"><a href="/books/n/nicecg111/ch4/" class="toc-item">4. Impact of bedwettingon children and young people and their families</a><ul id="toc_lst_NBK62712_ch4_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch4_s1"><a href="/books/n/nicecg111/ch4/#ch4.s1" class="toc-item">4.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch4_s2"><a href="/books/n/nicecg111/ch4/#ch4.s2" class="toc-item">4.2 What is the family impact of children and young people aged under 19 who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch5"><a href="/books/n/nicecg111/ch5/" class="toc-item">5. Patient Choice in children and young people with bedwetting</a><ul id="toc_lst_NBK62712_ch5_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch5_s1"><a href="/books/n/nicecg111/ch5/#ch5.s1" class="toc-item">5.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch5_s2"><a href="/books/n/nicecg111/ch5/#ch5.s2" class="toc-item">5.2 In children and young people with bedwetting, how does patient or parent/carer choice over treatment intervention influence treatment outcomes?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch6"><a href="/books/n/nicecg111/ch6/" class="toc-item">6. Assessment for children with Bedwetting</a><ul id="toc_lst_NBK62712_ch6_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch6_s1"><a href="/books/n/nicecg111/ch6/#ch6.s1" class="toc-item">6.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch6_s2"><a href="/books/n/nicecg111/ch6/#ch6.s2" class="toc-item">6.2 What are the core elements of initial clinical history and examination, and what are the core laboratory urine/blood tests in the evaluation of children and young people under 19 years old who have bedwetting?</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch6_s29"><a href="/books/n/nicecg111/ch6/#ch6.s29" class="toc-item">6.3 What is the incremental benefit and cost effectiveness of radiological examination, in the evaluation of children and young people under 19 years old who have bedwetting?</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch6_s49"><a href="/books/n/nicecg111/ch6/#ch6.s49" class="toc-item">6.4 What are the core elements of bladder diaries and other assessment tools, in the evaluation of children and young people under 19 years old who have bedwetting?</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch6_s60"><a href="/books/n/nicecg111/ch6/#ch6.s60" class="toc-item">6.5 How should a psychological assessment be conducted, in the evaluation of children and young people under 19 years old who have bedwetting?</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch6_s70"><a href="/books/n/nicecg111/ch6/#ch6.s70" class="toc-item">6.6 What is the clinical and cost effectiveness of additional investigation and treatment in children who have not responded to an adequate trial of both desmopressin and or alarms?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch7"><a href="/books/n/nicecg111/ch7/" class="toc-item">7. Fluid and diet restriction for the management of bedwetting</a><ul id="toc_lst_NBK62712_ch7_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch7_s1"><a href="/books/n/nicecg111/ch7/#ch7.s1" class="toc-item">7.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch7_s2"><a href="/books/n/nicecg111/ch7/#ch7.s2" class="toc-item">7.2 What is the clinical and cost effectiveness of fluid and/or diet restriction for children and young people under 19 years who have bedwetting?</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch7_s3"><a href="/books/n/nicecg111/ch7/#ch7.s3" class="toc-item">7.3 Fluid restriction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch7_s17"><a href="/books/n/nicecg111/ch7/#ch7.s17" class="toc-item">7.4 Dietary restriction</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch8"><a href="/books/n/nicecg111/ch8/" class="toc-item">8. Lifting and waking in the management of bedwetting</a><ul id="toc_lst_NBK62712_ch8_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch8_s1"><a href="/books/n/nicecg111/ch8/#ch8.s1" class="toc-item">8.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch8_s2"><a href="/books/n/nicecg111/ch8/#ch8.s2" class="toc-item">8.2 What is the clinical and cost effectiveness of lifting and waking for children and young people under 19 years who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch9"><a href="/books/n/nicecg111/ch9/" class="toc-item">9. Bladder training and retention control training for the management of bedwetting</a><ul id="toc_lst_NBK62712_ch9_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch9_s1"><a href="/books/n/nicecg111/ch9/#ch9.s1" class="toc-item">9.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch9_s2"><a href="/books/n/nicecg111/ch9/#ch9.s2" class="toc-item">9.2 What is the clinical and cost effectiveness of bladder training and retention control training for children and young people under 19 years who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch10"><a href="/books/n/nicecg111/ch10/" class="toc-item">10. Star Charts in the management of bedwetting</a><ul id="toc_lst_NBK62712_ch10_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch10_s1"><a href="/books/n/nicecg111/ch10/#ch10.s1" class="toc-item">10.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch10_s2"><a href="/books/n/nicecg111/ch10/#ch10.s2" class="toc-item">10.2 What is the clinical and cost effectiveness of the use of star charts for children and young people under 19 years who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch11"><a href="/books/n/nicecg111/ch11/" class="toc-item">11. Dry bed training for the management of bedwetting</a><ul id="toc_lst_NBK62712_ch11_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch11_s1"><a href="/books/n/nicecg111/ch11/#ch11.s1" class="toc-item">11.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch11_s2"><a href="/books/n/nicecg111/ch11/#ch11.s2" class="toc-item">11.2 What is the clinical and cost effectiveness of dry bed training for children and young people under 19 years who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch12"><a href="/books/n/nicecg111/ch12/" class="toc-item">12. Enuresis Alarms in the management of bedwetting</a><ul id="toc_lst_NBK62712_ch12_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch12_s1"><a href="/books/n/nicecg111/ch12/#ch12.s1" class="toc-item">12.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch12_s2"><a href="/books/n/nicecg111/ch12/#ch12.s2" class="toc-item">12.2 What is the clinical and cost effectiveness of enuresis alarms for children and young people under 19 years old who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch13"><a href="/books/n/nicecg111/ch13/" class="toc-item">13. Desmopressin and the management of bedwetting</a><ul id="toc_lst_NBK62712_ch13_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch13_s1"><a href="/books/n/nicecg111/ch13/#ch13.s1" class="toc-item">13.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch13_s2"><a href="/books/n/nicecg111/ch13/#ch13.s2" class="toc-item">13.2 What is the clinical and cost effectiveness of desmopressin for children and young people under 19 years who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch14"><a href="/books/n/nicecg111/ch14/" class="toc-item">14. Anticholinergic medication for the management of Nocturnal Enuresis</a><ul id="toc_lst_NBK62712_ch14_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch14_s1"><a href="/books/n/nicecg111/ch14/#ch14.s1" class="toc-item">14.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch14_s2"><a href="/books/n/nicecg111/ch14/#ch14.s2" class="toc-item">14.2 What is the clinical and cost effectiveness of anticholinergic medication for children and young people under 19 years who have nocturnal enuresis?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch15"><a href="/books/n/nicecg111/ch15/" class="toc-item">15. Tricyclic medication and the management of bedwetting</a><ul id="toc_lst_NBK62712_ch15_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch15_s1"><a href="/books/n/nicecg111/ch15/#ch15.s1" class="toc-item">15.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch15_s2"><a href="/books/n/nicecg111/ch15/#ch15.s2" class="toc-item">15.2 What is the clinical and cost effectiveness of tricyclic medication for children and young people under 19 years who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch16"><a href="/books/n/nicecg111/ch16/" class="toc-item">16. Dose escalation in the management of bedwetting</a><ul id="toc_lst_NBK62712_ch16_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch16_s1"><a href="/books/n/nicecg111/ch16/#ch16.s1" class="toc-item">16.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch16_s2"><a href="/books/n/nicecg111/ch16/#ch16.s2" class="toc-item">16.2 What is the clinical and cost effectiveness of dose escalation for children and young people under 19 years who have bedwetting</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch17"><a href="/books/n/nicecg111/ch17/" class="toc-item">17. Treatment for children who do not respond to initial treatment with desmopressin and / or enuresis alarms for the management of bedwetting</a><ul id="toc_lst_NBK62712_ch17_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch17_s1"><a href="/books/n/nicecg111/ch17/#ch17.s1" class="toc-item">17.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch17_s2"><a href="/books/n/nicecg111/ch17/#ch17.s2" class="toc-item">17.2 What is the clinical and cost effectiveness of additional treatment in children who have not responded to an adequate trial of desmopressin and / or enuresis alarms</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch18"><a href="/books/n/nicecg111/ch18/" class="toc-item">18. Treatment for children who have recurrence of bedwetting after previous successful treatment for bedwetting</a><ul id="toc_lst_NBK62712_ch18_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch18_s1"><a href="/books/n/nicecg111/ch18/#ch18.s1" class="toc-item">18.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch18_s2"><a href="/books/n/nicecg111/ch18/#ch18.s2" class="toc-item">18.2 What is the clinical and cost effectiveness of treating relapses in children after previously successful treatment for bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch19"><a href="/books/n/nicecg111/ch19/" class="toc-item">19. Psychological treatments for the management of bedwetting</a><ul id="toc_lst_NBK62712_ch19_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch19_s1"><a href="/books/n/nicecg111/ch19/#ch19.s1" class="toc-item">19.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch19_s2"><a href="/books/n/nicecg111/ch19/#ch19.s2" class="toc-item">19.2 What is the clinical and cost effectiveness of psychological interventions for children and young people under 19 years who have bedwetting</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch20"><a href="/books/n/nicecg111/ch20/" class="toc-item">20. Information and Educational interventions for the management of bedwetting</a><ul id="toc_lst_NBK62712_ch20_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch20_s1"><a href="/books/n/nicecg111/ch20/#ch20.s1" class="toc-item">20.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch20_s2"><a href="/books/n/nicecg111/ch20/#ch20.s2" class="toc-item">20.2 What is the clinical and cost effectiveness of information and educational interventions for children and young people under 19 years who have bedwetting</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch21"><a href="/books/n/nicecg111/ch21/" class="toc-item">21. Alternative treatments for the management of bedwetting</a><ul id="toc_lst_NBK62712_ch21_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch21_s1"><a href="/books/n/nicecg111/ch21/#ch21.s1" class="toc-item">21.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch21_s2"><a href="/books/n/nicecg111/ch21/#ch21.s2" class="toc-item">21.2 What is the clinical and cost effectiveness of alternative treatments for children and young people under 19 years who have bedwetting</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch22"><a href="/books/n/nicecg111/ch22/" class="toc-item">22. Under 5 year olds and management of bedwetting</a><ul id="toc_lst_NBK62712_ch22_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch22_s1"><a href="/books/n/nicecg111/ch22/#ch22.s1" class="toc-item">22.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch22_s2"><a href="/books/n/nicecg111/ch22/#ch22.s2" class="toc-item">22.2 In children under 5 years old with nocturnal enuresis, are there any preventative, prediction or treatment options which should be considered?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch23"><a href="/books/n/nicecg111/ch23/" class="toc-item">23. Support and follow-up for children with Bedwetting</a><ul id="toc_lst_NBK62712_ch23_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch23_s1"><a href="/books/n/nicecg111/ch23/#ch23.s1" class="toc-item">23.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch23_s2"><a href="/books/n/nicecg111/ch23/#ch23.s2" class="toc-item">23.2 What is the clinical and cost effectiveness of support and follow up care for children and young people under 19 years old who have bedwetting? What is the clinical and cost effectiveness of support and follow up care for the parents and carers of children and young people under 19 years old who have bedwetting?</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_ch24"><a href="/books/n/nicecg111/ch24/" class="toc-item">24. Network Meta-Analysis</a><ul id="toc_lst_NBK62712_ch24_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK62712_ch24_s1"><a href="/books/n/nicecg111/ch24/#ch24.s1" class="toc-item">24.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch24_s2"><a href="/books/n/nicecg111/ch24/#ch24.s2" class="toc-item">24.2 Comparability of interventions</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch24_s3"><a href="/books/n/nicecg111/ch24/#ch24.s3" class="toc-item">24.3 Methods</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch24_s7"><a href="/books/n/nicecg111/ch24/#ch24.s7" class="toc-item">24.4 Results</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch24_s8"><a href="/books/n/nicecg111/ch24/#ch24.s8" class="toc-item">24.5 Discussion</a></li><li class="half_rhythm" id="toc_itm_NBK62712_ch24_rl1"><a href="/books/n/nicecg111/ch24/#ch24.rl1" class="toc-item">24.6 Reference List</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app1"><a href="/books/n/nicecg111/appendixes.app1/" class="toc-item">Appendix A Nocturnal Enuresis Final Scope</a></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app2"><a href="/books/n/nicecg111/appendixes.app2/" class="toc-item">Appendix B Key Clinical Questions and Search Strategies</a></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app3"><a href="/books/n/nicecg111/appendixes.app3/" class="toc-item">Appendix C Clinical Evidence Extractions</a></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app4"><a href="/books/n/nicecg111/appendixes.app4/" class="toc-item">Appendix D Health Economic Extractions</a></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app5"><a href="/books/n/nicecg111/appendixes.app5/" class="toc-item">Appendix E Guideline Development Group Declarations of Interest</a></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app6"><a href="/books/n/nicecg111/appendixes.app6/" class="toc-item">Appendix F Network meta-analysis of interventions for the treatment of bedwetting</a></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app7"><a href="/books/n/nicecg111/appendixes.app7/" class="toc-item">Appendix G Cost-effectiveness analysis of intervention sequences for the treatment of bedwetting</a></li><li class="half_rhythm" id="toc_itm_NBK62712_appendixes_app8"><a href="/books/n/nicecg111/appendixes.app8/" class="toc-item">Appendix H GRADE profile tables</a></li></ul></div><div><h4 class="inline">Suggested citation:</h4><p>National Clinical Guideline Centre, (2010). Nocturnal enuresis: The management of bedwetting in children and young people. London: National Clinical Guideline Centre. Available from: [<a href="http://www.nice.org.uk" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">www.nice.org.uk</a>]</p></div></div></div>
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