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reference only and the information may be out of date.</strong></p><div class="main-content lit-style"><div class="fm-sec bkr_bottom_sep"><div class="bkr_thumb"><a href="http://guidance.nice.org.uk/CG87" title="National Institute for Health and Clinical Excellence (UK)" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg87-lrg.png" alt="Cover of Type 2 Diabetes" /></a></div><div class="bkr_bib"><h1 id="_NBK61842_"><span itemprop="name">Type 2 Diabetes</span></h1><div class="subtitle">Newer Agents for Blood Glucose Control in Type 2 Diabetes</div><p><i>NICE Clinical Guidelines, No. 87</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">Centre for Clinical Practice at NICE (UK)</span>.</p><div class="half_rhythm">London: <a href="http://guidance.nice.org.uk/CG87" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">National Institute for Health and Clinical Excellence (UK)</span></a>; <span itemprop="datePublished">2009 May</span>.</div><div><a href="/books/about/copyright/">Copyright</a> © 2009, National Institute for Health and Clinical Excellence.</div><a class="btn wsprkl bkr_rd" href="/books/n/nicecg87/nicecg87.fm.july2011update/?report=reader">Read</a></div><div class="bkr_clear"></div></div><div class="bkr_bottom_sep bkr_bottom_margin body-content whole_rhythm"><div itemprop="description"><p>This guideline covers newer agents for blood glucose control in adults with type 2 diabetes; it does not address care for pregnant women with diabetes. It is a partial update of ‘Type 2 diabetes’, NICE clinical guideline 66 (CG 66), published in 2008, which updated NICE clinical guidelines E, F, G and H (2002) and updated and replaced the recommendations on type 2 diabetes in NICE technology appraisal guidance 53 (2002), 60 and 63 (2003).</p><p>Specifically, this guideline updates and replaces recommendations in sections 1.6, 1.7.1.3, 1.7.2 and 1.7.3 of CG66. The new recommendations from this short guideline use the same levels of HbA<sub>1c</sub> for the addition of extra glucose-lowering drugs as defined in CG 66 (that is, a value of 6.5% for people on one glucose-lowering drug and 7.5% for people on two or more oral glucose-lowering drugs or people needing insulin). The use of these different levels takes into account the increasing risk of hypoglycaemia with insulin and the clinical and cost-effectiveness of the newer agents. Otherwise, CG 66 stands.</p><p>This short guideline addresses the licensed indications of drugs as of September 2008. The recommendations do not apply to drugs not yet available in the UK and exclude liraglutide which did not receive UK marketing authorisation for type 2 diabetes during the development of this guideline. Recommendations are consistent with safety information from the European Medicines Agency and the Medicines and Healthcare products Regulatory Agency.</p></div></div></div><div class="fm-sec"><div><p>This short clinical guideline partially updates NICE clinical guideline 66. The recommendations have been combined with unchanged recommendations from CG66 in NICE clinical guideline 87</p></div><div><p>NICE clinical guidelines are recommendations about the treatment and care of people with specific diseases and conditions in the NHS in England and Wales.</p><p>This guidance represents the view of NICE, which was arrived at after careful consideration of the evidence available. Healthcare professionals are expected to take it fully into account when exercising their clinical judgement. However, the guidance does not override the individual responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or guardian or carer, and informed by the summary of product characteristics of any drugs they are considering.</p><p>Implementation of this guidance is the responsibility of local commissioners and/or providers. Commissioners and providers are reminded that it is their responsibility to implement the guidance, in their local context, in light of their duties to avoid unlawful discrimination and to have regard to promoting equality of opportunity. Nothing in this guidance should be interpreted in a way that would be inconsistent with compliance with those duties.</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> © 2009, National Institute for Health and Clinical Excellence.<p class="small">All rights reserved. This material may be freely reproduced for educational and not-for-profit purposes. No reproduction by or for commercial organisations, or for commercial purposes, is allowed without the express written permission of NICE.</p></div><div class="small"><span class="label">Bookshelf ID: NBK61842</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/22220323" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">22220323</a></span></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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