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/></a></div><div class="bkr_bib"><h1 id="_NBK612413_"><span itemprop="name">Evidence reviews for healthy and appropriate weight change during pregnancy</span></h1><div class="subtitle">Maternal and child nutrition</div><p><b>Evidence review F</b></p><p><i>NICE Guideline, No. 247</i></p><div class="half_rhythm">London: <a href="https://www.nice.org.uk" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">National Institute for Health and Care Excellence (NICE)</span></a>; <span itemprop="datePublished">2025 Jan</span>.<div class="small">ISBN-13: <span itemprop="isbn">978-1-4731-6748-3</span></div></div><div><a href="/books/about/copyright/">Copyright</a> © NICE 2025.</div></div><div class="bkr_clear"></div></div><div id="niceng247er6.s1"><h2 id="_niceng247er6_s1_">Healthy and appropriate weight change during pregnancy</h2><div id="niceng247er6.s1.1"><h3>Review question</h3><p>What gestational weight change is healthy and appropriate during pregnancy?</p><div id="niceng247er6.s1.1.1"><h4>Introduction</h4><p>Weight gain in pregnancy is comprised of the weight of the uterus, fetus and placenta, increased maternal blood volume, amniotic fluid and increased of maternal fat mass. Weight change during pregnancy can be linked with adverse maternal and fetal outcomes, however, the ranges of appropriate weight gain has been uncertain. In recent years extensive effort has been directed towards trying to define appropriate levels of GWG, including evaluation of the safety of adoption of the estimated ranges of appropriate total weight gain during pregnancy for those in the underweight, healthy, overweight and obese BMI categories reported by the USA Institute of Medicine (<a class="bibr" href="#niceng247er6.s1.ref40" rid="niceng247er6.s1.ref40">IOM 2009</a>), now the National Academy of Medicine (NAM). These have been widely implemented globally, but not in the UK. The aim of this review is to determine what gestational weight change is healthy and appropriate during pregnancy.</p></div><div id="niceng247er6.s1.1.2"><h4>Summary of the protocol</h4><p>See <a href="/books/NBK612413/table/niceng247er6.tab1/?report=objectonly" target="object" rid-ob="figobniceng247er6tab1">Table 1</a> for a summary of the Population, Presence or absence of a prognostic risk factor, and Outcome (PPO) characteristics of this review.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6tab1"><a href="/books/NBK612413/table/niceng247er6.tab1/?report=objectonly" target="object" title="Table 1" class="img_link icnblk_img" rid-ob="figobniceng247er6tab1"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.tab1"><a href="/books/NBK612413/table/niceng247er6.tab1/?report=objectonly" target="object" rid-ob="figobniceng247er6tab1">Table 1</a></h4><p class="float-caption no_bottom_margin">Summary of the protocol (PPO table). </p></div></div><p>For further details see the review protocol in <a href="#niceng247er6.appa">appendix A</a>.</p></div><div id="niceng247er6.s1.1.3"><h4>Methods and process</h4><p>This evidence review was developed using the methods and process described in <a href="https://www.nice.org.uk/process/pmg20/chapter/introduction" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>. Methods specific to this review question are described in the review protocol in <a href="#niceng247er6.appa">appendix A</a> and the <a href="/books/NBK612413/bin/NG247-Supp1-methods.pdf">methods</a> document (supplementary document 1).</p><p>Declarations of interest were recorded according to <a href="https://www.nice.org.uk/about/who-we-are/policies-and-procedures" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NICE’s conflicts of interest policy</a>.</p></div><div id="niceng247er6.s1.1.4"><h4>Prognostic evidence</h4><div id="niceng247er6.s1.1.4.1"><h5>Included studies</h5><p>Thirty-nine studies were included for this review:
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<ul><li class="half_rhythm"><div>9 prospective cohort studies (<a class="bibr" href="#niceng247er6.s1.ref4" rid="niceng247er6.s1.ref4">Breckenkamp 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref5" rid="niceng247er6.s1.ref5">Cedergren 2006</a>, <a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref13" rid="niceng247er6.s1.ref13">Gaillard 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref20" rid="niceng247er6.s1.ref20">Haugen 2014</a>, <a class="bibr" href="#niceng247er6.s1.ref26" rid="niceng247er6.s1.ref26">Lautredou 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref30" rid="niceng247er6.s1.ref30">Morken 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref33" rid="niceng247er6.s1.ref33">Premru-Srsen 2019</a>, and <a class="bibr" href="#niceng247er6.s1.ref36" rid="niceng247er6.s1.ref36">Tanigawa 2022</a>)</div></li><li class="half_rhythm"><div>26 retrospective cohort studies (<a class="bibr" href="#niceng247er6.s1.ref1" rid="niceng247er6.s1.ref1">Beaudrot 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref2" rid="niceng247er6.s1.ref2">Beyerlein 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref3" rid="niceng247er6.s1.ref3">Blomberg 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref7" rid="niceng247er6.s1.ref7">Chen L 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref9" rid="niceng247er6.s1.ref9">Chuang 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref10" rid="niceng247er6.s1.ref10">Di Benedetto 2012</a>, <a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref12" rid="niceng247er6.s1.ref12">Flick 2010</a>, <a class="bibr" href="#niceng247er6.s1.ref14" rid="niceng247er6.s1.ref14">Gante 2015</a>, <a class="bibr" href="#niceng247er6.s1.ref15" rid="niceng247er6.s1.ref15">Gavard 2017</a>, <a class="bibr" href="#niceng247er6.s1.ref16" rid="niceng247er6.s1.ref16">Gawade 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref17" rid="niceng247er6.s1.ref17">Graham 2014</a>, <a class="bibr" href="#niceng247er6.s1.ref18" rid="niceng247er6.s1.ref18">Haile 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref19" rid="niceng247er6.s1.ref19">Harper 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref21" rid="niceng247er6.s1.ref21">Hautier 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref23" rid="niceng247er6.s1.ref23">Kiefer 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref24" rid="niceng247er6.s1.ref24">Kominiarek 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref25" rid="niceng247er6.s1.ref25">Langford 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref27" rid="niceng247er6.s1.ref27">Liang 2021</a>, <a class="bibr" href="#niceng247er6.s1.ref29" rid="niceng247er6.s1.ref29">McCurdy 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref31" rid="niceng247er6.s1.ref31">Nohr 2008</a>, <a class="bibr" href="#niceng247er6.s1.ref32" rid="niceng247er6.s1.ref32">Park 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref35" rid="niceng247er6.s1.ref35">Simko 2019</a>, and <a class="bibr" href="#niceng247er6.s1.ref39" rid="niceng247er6.s1.ref39">Yee 2013</a>)</div></li><li class="half_rhythm"><div>2 systematic reviews of observational studies (<a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a> and <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>) and</div></li><li class="half_rhythm"><div>2 individual patient data (IPD) meta-analyses (<a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> and <a class="bibr" href="#niceng247er6.s1.ref37" rid="niceng247er6.s1.ref37">Voerman 2019</a>).</div></li></ul></p><p>The included studies are summarised in <a href="/books/NBK612413/table/niceng247er6.tab2/?report=objectonly" target="object" rid-ob="figobniceng247er6tab2">Table 2</a>.</p><p>Two studies were conducted on twin pregnancies (<a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a> and <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>), all other studies were conducted on single pregnancies.</p><p>Twenty-nine studies used the Institute of Medicine (IOM) gestational weight gain guidelines (<a class="bibr" href="#niceng247er6.s1.ref1" rid="niceng247er6.s1.ref1">Beaudrot 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref2" rid="niceng247er6.s1.ref2">Beyerlein 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref3" rid="niceng247er6.s1.ref3">Blomberg 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref4" rid="niceng247er6.s1.ref4">Breckenkamp 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref10" rid="niceng247er6.s1.ref10">Di Benedetto 2012</a>, <a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref12" rid="niceng247er6.s1.ref12">Flick 2010</a>, <a class="bibr" href="#niceng247er6.s1.ref13" rid="niceng247er6.s1.ref13">Gaillard 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref14" rid="niceng247er6.s1.ref14">Gante 2015</a>, <a class="bibr" href="#niceng247er6.s1.ref15" rid="niceng247er6.s1.ref15">Gavard 2017</a>, <a class="bibr" href="#niceng247er6.s1.ref18" rid="niceng247er6.s1.ref18">Haile 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref19" rid="niceng247er6.s1.ref19">Harper 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref20" rid="niceng247er6.s1.ref20">Haugen 2014</a>, <a class="bibr" href="#niceng247er6.s1.ref21" rid="niceng247er6.s1.ref21">Hautier 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref23" rid="niceng247er6.s1.ref23">Kiefer 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref25" rid="niceng247er6.s1.ref25">Langford 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref26" rid="niceng247er6.s1.ref26">Lautredou 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref27" rid="niceng247er6.s1.ref27">Liang 2021</a>, <a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref29" rid="niceng247er6.s1.ref29">McCurdy 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref32" rid="niceng247er6.s1.ref32">Park 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref35" rid="niceng247er6.s1.ref35">Simko 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref36" rid="niceng247er6.s1.ref36">Tanigawa 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref37" rid="niceng247er6.s1.ref37">Voerman 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>), 1 study used a combination of guidelines (<a class="bibr" href="#niceng247er6.s1.ref9" rid="niceng247er6.s1.ref9">Chuang 2022</a>), and 9 studies used independent thresholds (<a class="bibr" href="#niceng247er6.s1.ref5" rid="niceng247er6.s1.ref5">Cedergren 2006</a>, <a class="bibr" href="#niceng247er6.s1.ref7" rid="niceng247er6.s1.ref7">Chen L 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref16" rid="niceng247er6.s1.ref16">Gawade 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref17" rid="niceng247er6.s1.ref17">Graham 2014</a>, <a class="bibr" href="#niceng247er6.s1.ref24" rid="niceng247er6.s1.ref24">Kominiarek 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref30" rid="niceng247er6.s1.ref30">Morken 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref31" rid="niceng247er6.s1.ref31">Nohr 2008</a>, <a class="bibr" href="#niceng247er6.s1.ref33" rid="niceng247er6.s1.ref33">Premru-Srsen 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref39" rid="niceng247er6.s1.ref39">Yee 2013</a>).</p><p>Thirty studies assessed the association between gestational weight gain and caesarean birth (<a class="bibr" href="#niceng247er6.s1.ref1" rid="niceng247er6.s1.ref1">Beaudrot 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref2" rid="niceng247er6.s1.ref2">Beyerlein, 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref3" rid="niceng247er6.s1.ref3">Blomberg 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref4" rid="niceng247er6.s1.ref4">Breckenkamp 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref5" rid="niceng247er6.s1.ref5">Cedergren 2006</a>, <a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref10" rid="niceng247er6.s1.ref10">Di Benedetto 2012</a>, <a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref12" rid="niceng247er6.s1.ref12">Flick 2010</a>, <a class="bibr" href="#niceng247er6.s1.ref13" rid="niceng247er6.s1.ref13">Gaillard 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref14" rid="niceng247er6.s1.ref14">Gante 2015</a>, <a class="bibr" href="#niceng247er6.s1.ref15" rid="niceng247er6.s1.ref15">Gavard 2017</a>, <a class="bibr" href="#niceng247er6.s1.ref16" rid="niceng247er6.s1.ref16">Gawade 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref17" rid="niceng247er6.s1.ref17">Graham 2014</a>, <a class="bibr" href="#niceng247er6.s1.ref18" rid="niceng247er6.s1.ref18">Haile 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref19" rid="niceng247er6.s1.ref19">Harper 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref20" rid="niceng247er6.s1.ref20">Haugen 2014</a>, <a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref23" rid="niceng247er6.s1.ref23">Kiefer 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref24" rid="niceng247er6.s1.ref24">Kominiarek 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref25" rid="niceng247er6.s1.ref25">Langford 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref26" rid="niceng247er6.s1.ref26">Lautredou 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref29" rid="niceng247er6.s1.ref29">McCurdy 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref30" rid="niceng247er6.s1.ref30">Morken 2013</a>, <a class="bibr" href="#niceng247er6.s1.ref31" rid="niceng247er6.s1.ref31">Nohr 2008</a>, <a class="bibr" href="#niceng247er6.s1.ref35" rid="niceng247er6.s1.ref35">Simko 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref39" rid="niceng247er6.s1.ref39">Yee 2013</a>). 8 studies assessed the association between gestational weight gain and preeclampsia (<a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref7" rid="niceng247er6.s1.ref7">Chen L 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref33" rid="niceng247er6.s1.ref33">Premru-Srsen 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>). 6 studies assessed the association between gestational weight gain and gestational hypertension (<a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref26" rid="niceng247er6.s1.ref26">Lautredou 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>). 9 studies assessed the association between gestational weight gain and gestational diabetes (<a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref9" rid="niceng247er6.s1.ref9">Chuang 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref26" rid="niceng247er6.s1.ref26">Lautredou 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>).</p><p>Eight studies assessed the association between gestational weight gain and small for gestational age (<a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref21" rid="niceng247er6.s1.ref21">Hautier 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref32" rid="niceng247er6.s1.ref32">Park 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>).10 studies assessed the association between gestational weight gain and large for gestational age (<a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a>, <a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref10" rid="niceng247er6.s1.ref10">Di Benedetto 2012</a>, <a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a>, <a class="bibr" href="#niceng247er6.s1.ref26" rid="niceng247er6.s1.ref26">Lautredou 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref27" rid="niceng247er6.s1.ref27">Liang 2021</a>, <a class="bibr" href="#niceng247er6.s1.ref32" rid="niceng247er6.s1.ref32">Park 2011</a>, <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a>, <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>). 2 studies assessed the association between gestational weight gain and childhood overweight or obesity (<a class="bibr" href="#niceng247er6.s1.ref36" rid="niceng247er6.s1.ref36">Tanigawa 2022</a>, <a class="bibr" href="#niceng247er6.s1.ref37" rid="niceng247er6.s1.ref37">Voerman 2019</a>).</p><p>All studies adjusted for covariates; however, the committee did not agree on key covariates a priori in the protocol. The adjusted covariates varied across the studies.</p><p>All studies used the World Health Organization definition of BMI categories when reporting pre-pregnancy BMI.</p><p>The studies used different definitions of gestational weight change (for example, IOM categories of weight change, Swedish categories of weight change) and different methods of weight measurement (for example, self-reported, by healthcare professional at antenatal care appointments). Overall, most studies used the IOM categories for gestational weight change. Studies defined gestational weight change as weight loss, inadequate weight gain, adequate weight gain, or excessive weight gain. Only studies using the same gestational weight change categories and definitions were pooled. Where possible, similarly defined outcomes have been pooled. Since all studies reported results by inadequate or excessive gestational weight change, studies have not been analysed by when gestational weight was measured (for example, gestational weight change at different time points such as 1st, 2nd or 3rd trimester). All studies had a referent population (usually adequate weight gain), but there was some variation in studies (for example, specific weight gain categories such as weight gain of 15-24.9 lbs). Only studies using the same referent population were pooled.</p><p>Evidence was identified for all outcomes other than health related quality of life.</p><p>See the literature search strategy in <a href="#niceng247er6.appb">appendix B</a> and study selection flow chart in <a href="#niceng247er6.appc">appendix C</a>.</p><p>The evidence was stratified by BMI and parity (nulliparous and parous) where possible. No evidence was identified to stratify evidence according to ethnicity and bariatric surgery.</p></div><div id="niceng247er6.s1.1.4.2"><h5>Excluded studies</h5><p>Studies not included in this review are listed, and reasons for their exclusion are provided in <a href="#niceng247er6.appk">appendix K</a>.</p></div></div><div id="niceng247er6.s1.1.5"><h4>Summary of included studies</h4><p>Summaries of the studies that were included in this review are presented in <a href="/books/NBK612413/table/niceng247er6.tab2/?report=objectonly" target="object" rid-ob="figobniceng247er6tab2">Table 2</a>.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6tab2"><a href="/books/NBK612413/table/niceng247er6.tab2/?report=objectonly" target="object" title="Table 2" class="img_link icnblk_img" rid-ob="figobniceng247er6tab2"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.tab2"><a href="/books/NBK612413/table/niceng247er6.tab2/?report=objectonly" target="object" rid-ob="figobniceng247er6tab2">Table 2</a></h4><p class="float-caption no_bottom_margin">Summary of included studies. </p></div></div><p>See the full evidence tables in <a href="#niceng247er6.appd">appendix D</a> and the forest plots in <a href="#niceng247er6.appe">appendix E</a>.</p></div><div id="niceng247er6.s1.1.6"><h4>Summary of the evidence</h4><p>See <a href="#niceng247er6.appf">appendix F</a> for full GRADE tables.</p><p>Meta-analysis was performed where possible (for example, if there were at least 2 studies reporting the same risk factor and in populations with the same/similar characteristics) and where there was no significant variation between studies or very serious heterogeneity. Studies adjusting for the same covariates (or matched at baseline) or with an overlap of adjusted covariates were meta-analysed. For those where meta-analysis could not be performed (for example, where there was very serious heterogeneity (I<sup>2</sup> > 80%)), the results for each individual study have been reported in this review. Meta-analysis was possible for 31 studies and for 10 studies risk factors were reported individually.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6tab3"><a href="/books/NBK612413/table/niceng247er6.tab3/?report=objectonly" target="object" title="Table" class="img_link icnblk_img" rid-ob="figobniceng247er6tab3"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.tab3"><a href="/books/NBK612413/table/niceng247er6.tab3/?report=objectonly" target="object" rid-ob="figobniceng247er6tab3">Table</a></h4><p class="float-caption no_bottom_margin">Association between weight loss, inadequate gestational weight gain, excessive gestational weight gain (IOM gestational weight change categories) and maternal/neonatal/fetal outcomes in singleton and twin pregnancy: all BMI categories, parity and age <a href="/books/NBK612413/table/niceng247er6.tab3/?report=objectonly" target="object" rid-ob="figobniceng247er6tab3">(more...)</a></p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6tab4"><a href="/books/NBK612413/table/niceng247er6.tab4/?report=objectonly" target="object" title="Table" class="img_link icnblk_img" rid-ob="figobniceng247er6tab4"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.tab4"><a href="/books/NBK612413/table/niceng247er6.tab4/?report=objectonly" target="object" rid-ob="figobniceng247er6tab4">Table</a></h4><p class="float-caption no_bottom_margin">Association between low, medium, high gestational weight change (study defined category) and maternal/neonatal/fetal outcomes in singleton pregnancy: all BMI categories strata. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6tab5"><a href="/books/NBK612413/table/niceng247er6.tab5/?report=objectonly" target="object" title="Table" class="img_link icnblk_img" rid-ob="figobniceng247er6tab5"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.tab5"><a href="/books/NBK612413/table/niceng247er6.tab5/?report=objectonly" target="object" rid-ob="figobniceng247er6tab5">Table</a></h4><p class="float-caption no_bottom_margin">Association between low (<8 kg) gestational weight gain and high (>16 kg) gestational weight gain (Independent Swedish gestational weight change categories) and maternal/neonatal/fetal outcomes in singleton pregnancy: all BMI categories <a href="/books/NBK612413/table/niceng247er6.tab5/?report=objectonly" target="object" rid-ob="figobniceng247er6tab5">(more...)</a></p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6tab6"><a href="/books/NBK612413/table/niceng247er6.tab6/?report=objectonly" target="object" title="Table" class="img_link icnblk_img" rid-ob="figobniceng247er6tab6"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.tab6"><a href="/books/NBK612413/table/niceng247er6.tab6/?report=objectonly" target="object" rid-ob="figobniceng247er6tab6">Table</a></h4><p class="float-caption no_bottom_margin">Association between gestational weight change of <0.5 to 6.9 kg, 6.7 to 10 kg, 13.7 to 29 kg and >24.6 to ≥29.1 kg (Swedish gestational weight change categories) and maternal/neonatal/fetal outcomes in singleton pregnancy: all <a href="/books/NBK612413/table/niceng247er6.tab6/?report=objectonly" target="object" rid-ob="figobniceng247er6tab6">(more...)</a></p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6tab7"><a href="/books/NBK612413/table/niceng247er6.tab7/?report=objectonly" target="object" title="Table" class="img_link icnblk_img" rid-ob="figobniceng247er6tab7"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.tab7"><a href="/books/NBK612413/table/niceng247er6.tab7/?report=objectonly" target="object" rid-ob="figobniceng247er6tab7">Table</a></h4><p class="float-caption no_bottom_margin">Association between Weight change (thresholds as reported in the studies) and maternal/neonatal/fetal outcomes in singleton pregnancy. </p></div></div></div><div id="niceng247er6.s1.1.7"><h4>Economic evidence</h4><div id="niceng247er6.s1.1.7.1"><h5>Included studies</h5><p>No economic studies were identified which were applicable to this review question. See the literature search strategy in <a href="#niceng247er6.appb">appendix B</a> and economic study selection flow chart in <a href="#niceng247er6.appg">appendix G</a>.</p></div><div id="niceng247er6.s1.1.7.2"><h5>Excluded studies</h5><p>Economic studies not included in this review are listed, and reasons for their exclusion are provided in <a href="#niceng247er6.appj">appendix J</a>.</p></div></div><div id="niceng247er6.s1.1.8"><h4>Economic model</h4><p>No economic modelling was undertaken for this review because the committee agreed that other topics were higher priorities for economic evaluation.</p></div><div id="niceng247er6.s1.1.9"><h4>The committee’s discussion and interpretation of the evidence</h4><div id="niceng247er6.s1.1.9.1"><h5>The outcomes that matter most</h5><p>The committee agreed to prioritise the maternal outcomes of caesarean birth, hypertensive disorders of pregnancy, and gestational diabetes; fetal outcomes of SGA and LGA; and childhood outcomes of overweight/obesity as critical outcomes, and health related quality of life as an important outcome. These outcomes are in line with a core outcome set defined in the evidence base.</p></div><div id="niceng247er6.s1.1.9.2"><h5>The quality of the evidence</h5><p>The quality of the evidence was assessed with an adapted GRADE approach and the overall quality of the evidence ranged from very low to high.</p><p>The evidence was downgraded due to methodological limitations in studies (for example, issues with study participation or with prognostic factors measurement), indirectness (for example, outcome indirectness such as, including macrosomia for LGA), and imprecision around the effect estimate. Some evidence was downgraded as a result of serious or very serious heterogeneity that was unexplained by sub-group analysis.</p><p>Data were identified for all outcomes except health-related quality of life.</p></div><div id="niceng247er6.s1.1.9.3"><h5>Benefits and harms</h5><p>Overall, the committee thought that the evidence was difficult to interpret because of the different categories used to define gestational weight change and because weight change was reported as total weight gain in pregnancy instead of trimester specific weight gain in the studies reviewed. This made it difficult to give practical advice about appropriate or inappropriate weight change during different stages of pregnancy.</p><p>The committee discussed that weight change in pregnancy is a sensitive and complicated issue. They were aware that many people have negative experiences when being weighed, or when weight or BMI is being discussed in clinical settings. For example, they may feel judged if they have a higher pre-pregnancy BMI, they may experience that their other health concerns are attributed to their weight inappropriately or unnecessarily. Things can be particularly complicated if they have a history of eating disorders. Sometimes - discussions around weight may be more difficult if their partner is present. The committee agreed it was important to handle these discussions with care to avoid stigmatising the individual. The committee referred to the recommendations in the <a href="https://www.nice.org.uk/guidance/indevelopment/gid-ng10182" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NICE guideline on overweight and obesity management</a> about how to discuss weight in a sensitive manner. Offering to measure height and weight and calculating BMI in the first antenatal (booking) appointment is current practice and helps healthcare providers to plan care and assess for risk factors, as is recommended in the <a href="https://www.nice.org.uk/guidance/ng201" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NICE guideline on antenatal care</a>. The committee discussed that unless there are clinical reasons, sharing the weight and BMI with the person at the booking appointment is not always necessary, but if it is it should be shared in a sensitive manner or discreetly, for example so that it is not said out loud but written down instead.</p><p>The committee noted that most of the evidence identified reported results according to the IOM (now called the National Academy of Medicine, NAM and referred to as such in the recommendations) categories on gestational weight change during pregnancy, which estimates appropriate weight change ranges according to pre-pregnancy BMI groups (underweight, healthy weight, overweight, obesity). The committee also noted that the categories report total gestational weight change during pregnancy rather than trimester specific gestational weight change, which is important as weight change does not occur equally in each trimester. Although NAM provides some trimester specific guidance, this has not been rigorously validated and therefore its relevance to, and safety for, pregnancy outcomes is unclear.</p><p>The committee were aware that the IOM/NAM categories were developed by balancing the risk between small for gestational age (SGA) and large for gestational age (LGA), and the risk of caesarean section and postpartum weight retention. However, gestational diabetes and preeclampsia were not considered in the development of the categories. The committee discussed that because of the way it was developed, the IOM/NAM categories should be applied and interpreted with caution. Furthermore, the committee were aware that currently nearly half of pregnancies worldwide have a gestational weight change during pregnancy that is more than the IOM/NAM recommended weight change categories, potentially reducing relevance to the population today. The committee also noticed that currently the IOM/NAM recommended categories for people with a pre-pregnancy BMI in the obesity range are grouped together rather than by different obesity categories (for example, class I, II, or III). However, the committee agreed there are no better alternatives available at the moment. Based on the evidence and their expertise, the committee agreed that the estimates for optimal total weight change during pregnancy remain uncertain and not well defined for all pre-pregnancy BMI groups, but the IOM/NAM recommendations may provide helpful estimates for total appropriate weight gain in pregnancy and referred to these in the recommendations. However, what is particularly uncertain is what the week by week weight change in each trimester should be.</p><p>The committee agreed that the evidence does not support weighing everyone throughout pregnancy and this should only be offered when there is a clinical need (for example, if the person has gestational diabetes or need for thromboprophylaxis, or if there are nutrition concerns due to hyperemesis gravidarum). This is further discussed in evidence review G. Because of the uncertainties around optimal weight change in pregnancy, the committee agreed that the focus during pregnancy should instead be on healthy eating and physical activity which have positive associations with health benefits for the mother and the baby.</p><p>The committee discussed that not only are there uncertainties about what is healthy weight change in pregnancy, but the normal physiological changes during pregnancy contributing to the weight change, such as weight of the growing fetus, weight of the placenta, increase in maternal blood volume, breast tissue expansion, and volume of amniotic fluid can vary between individuals across all these contributing factors but especially in relation to the weight of the baby.</p><p>However, they acknowledged that some people may want to monitor their weight themselves throughout pregnancy. Quantitative evidence was unable to determine the optimal weight change during pregnancy; however, there are estimates of healthy total weight change in a singleton pregnancy according to the pre pregnancy BMI that healthcare professionals can refer to (Table 1 in the National Academy of Medicine’s report on the current understanding of gestational weight gain among women with obesity and the need for future research). But these estimates do not account for trimester specific healthy weight change. The committee noted that there are separate estimates for twin pregnancies, although there is even more uncertainty around these estimates. The committee notes that because of the wide ranges in the NAM/IOM estimates and because they estimate total weight change in the whole of pregnancy, they are not particularly helpful in practice.</p><p>The committee recognised that some people who want to monitor their weight might not have access to weighing scales but discussed that these should be available in health care settings or community hubs where people can be advised to go. The committee discussed the difficulties and risks of weight management during pregnancy and agreed that pre-conception weight management should be a priority because weight before pregnancy is potentially a modifiable factor. The committee agreed that pre-pregnancy BMI is a bigger risk factor for adverse maternal and fetal outcomes than gestational weight change during pregnancy. However, weight management before pregnancy is outside the remit of this guideline and is covered in the <a href="https://www.nice.org.uk/guidance/indevelopment/gid-ng10182" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NICE guideline on overweight and obesity management</a>.</p><p>Overall, the meta-analysed data and data from the individual participant data meta-analysis suggested that weight change exceeding the IOM/NAM estimated categories was associated with negative maternal and fetal outcomes. Generally, there was moderate to high quality evidence which suggested an association between excessive gestational weight gain and the outcomes caesarean birth, gestational diabetes, gestational hypertension and large for gestational age for pregnant women with a pre-pregnancy BMI within the healthy, overweight, and obesity ranges. The committee noted that although the relative data suggested these associations for risk, there was no absolute data showing that excessive gestational weight gain in a pre-pregnancy BMI of overweight or obesity ranges leads to more negative outcomes than in those with a lower pre-pregnancy BMI. Despite this, the committee agreed that maintaining a healthy pre-pregnancy BMI would lead to the most optimum outcomes for the mother and the baby.</p><p>There was high quality evidence from the individual participant data meta-analysis which showed an association for women with a pre-pregnancy BMI in the obesity range and excessive gestational weight gain for the outcomes of caesarean birth, gestational diabetes, pre-eclampsia and large for gestational age. The committee agreed that this overall trend (weight change exceeding the IOM/NAM estimated categories associated with negative maternal and fetal outcomes) resonated with their clinical and research experience, and therefore these should be discussed. Alongside these risks, it is also important to consider individual level factors that might affect development of these outcomes, for example, comorbidities, family history and obstetric history. The committee noted that there was evidence from 1 study (<a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a>) conducted in Japan where those with pre-pregnancy BMI in the obesity range and who gained excessive gestational weight, showed no association for caesarean birth, gestational diabetes, and gestational hypertension. The committee discussed that because these results were of low quality and were based on Japanese women, they were less applicable to the majority of the population in England and Wales.</p><p>Moderate to high quality evidence from the meta-analysis from this review and data from the individual participant data meta-analysis included in this review suggested that weight change exceeding the IOM/NAM estimated categories in people with a healthy pre-pregnancy BMI was associated with gestational diabetes, gestational hypertension, preeclampsia, and baby being large for gestational age. Data from the individual participant data meta-analysis suggested there was a lower risk of small for gestational age babies with excessive gestational weight gain for all pre-pregnancy BMI ranges, when compared to normal gestational weight gain in those with a healthy pre-pregnancy BMI. The committee discussed that pregnant people with a healthy pre-pregnancy BMI who rapidly gain weight during pregnancy is a population that is largely missed and therefore adverse outcomes are likely to be more problematic in this population than in people with a higher pre-pregnancy BMI with excessive gestational weight change in pregnancy, who may be under closer observation. The committee were aware from their knowledge that there is not as much guidance on pregnant people with a healthy pre-pregnancy BMI as it is assumed that this population is at a lower risk of negative maternal and fetal outcomes.</p><p>Overall, the committee concluded from the evidence that those with pre-pregnancy BMI in the healthy, overweight and obesity ranges who gain excessive weight during pregnancy are at an increased risk of some obstetric complications, including developing gestational hypertension or gestational diabetes, baby being large for gestational age, or needing a caesarean section. The committee noted that large for gestational age is frequently an indicator for caesarean birth, and therefore this outcome is not independent of caesarean birth.</p><p>The committee acknowledged that because the evidence does not justify routine weight monitoring in pregnancy, excess weight gain is also not routinely identified. They agreed that if there are concerns about excessive gestational weight gain during pregnancy raised by the pregnant person, or by a healthcare professional as part of weight monitoring for a clinical reason, this should be explored further, and information about healthy eating and physical activity should be discussed. The committee agreed that there may be various underlying reasons for excessive weight gain during pregnancy, and a holistic exploration of the person’s wellbeing is important. Based on the evidence of excessive weight gain being associated with baby being born large for gestational age and with gestational diabetes, the committee recommended that the baby should be monitored for large for gestational age and a test for gestational diabetes should be considered. It should be noted that those with a BMI of 30 or more at the booking appointment should already be offered an oral glucose tolerance test according to the <a href="https://www.nice.org.uk/guidance/ng3" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NICE guideline on diabetes in pregnancy</a>, but the committee agreed a referral to the test should be considered regardless of the pre-pregnancy BMI if there are concerns about excessive gestational weight gain.</p><p>In terms of too low weight gain during pregnancy, there was high quality evidence from the individual participant data meta-analysis, which showed an increased risk of baby being small for gestational age in those with pre-pregnancy BMI in the underweight and healthy ranges who had low or inadequate weight gain during pregnancy. Moderate quality evidence from other meta-analysed studies also showed an association between inadequate weight gain and baby being small for gestational age among those with pre-pregnancy BMI in the underweight range. Low quality evidence across all pre-pregnancy BMI ranges also showed an association with inadequate weight gain and baby being small for gestational age.</p><p>There was low to moderate quality evidence from the individual participant data meta-analysis among those with a pre-pregnancy BMI in the underweight or healthy weight ranges and low gestational weight gain that showed no association of risk for gestational diabetes, however, low to moderate quality evidence from other meta-analysed studies suggested that weight change below the IOM/NAM estimated categories in those with a pre-pregnancy BMI in the underweight or healthy weight ranges was associated with a high risk of gestational diabetes. The committee discussed that this association might be due to participants in this study being diagnosed with gestational diabetes during their second trimester of pregnancy, therefore receiving dietary and exercise advice to control their gestational weight change during the third trimester. It is likely that this would have strongly contributed to the overall gestational weight change as most weight change occurs over this period. The committee noted that the studies reported weight change as the difference between weight prior to birth and pre-pregnancy body weight, and therefore there is uncertainty around how much weight changed by trimester and the causal relationship between low gestational weight change and gestational diabetes.</p><p>From their collective experience, the committee agreed that there may be various reasons for low weight gain during pregnancy, for example, nausea and vomiting in pregnancy, mental health issues, or clinical interventions that have been recommended for the person, for example, after a diagnosis of gestational diabetes.</p><p>As with excessive gestational weight gain, the committee acknowledged that because the evidence does not justify routine weight monitoring in pregnancy, low weight gain is also not routinely identified. The committee agreed that when there are concerns about low weight gain during pregnancy raised by the pregnant person, or by a healthcare professional as part of weight monitoring for a clinical reason, this should be further explored through individualised discussions about healthy eating and physical activity in pregnancy because advice required for those with low gestational weight gain will likely be different to advice needed for those with excessive gestational weight gain. The committee also agreed that routine monitoring of the growth of the baby (according to the NICE guideline on antenatal care) to check for small for gestational age should be ensured when there are concerns about low weight gain during pregnancy. The committee discussed that for some people, a lifestyle change of healthier eating and increasing physical activity might lead to weight loss. The committee considered it was important to discuss the potential impact of overly restrictive eating and drinking habits.</p><p>Overall, the results suggest that gestational weight gain exceeding the IOM/NAM estimated categories is associated with an increased risk of overweight and obesity in childhood. There was high quality evidence from individual participant data meta-analysis for all pre-pregnancy BMI categories and excessive gestational weight gain that showed a high risk of childhood overweight or obesity at 2 to 18 years of age, and with low gestational weight gain showed a low risk of childhood overweight or obesity at 2 to 10 years, and no association at 10 to 18 years. High and moderate quality evidence from 1 study from Japan supported these findings and also found that people within the obesity pre-pregnancy BMI range with low gestational weight gain also had a high risk for childhood overweight or obesity at 3 years. The committee discussed that gestational weight gain is not only associated with maternal outcomes but is also associated with childhood outcomes. The committee agreed that pre-pregnancy BMI is an important modifiable risk factor of childhood weight status, which is currently a significant public health concern. To support people with weight management, the committee referred to the <a href="https://www.nice.org.uk/guidance/indevelopment/gid-ng10182" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NICE guideline on overweight and obesity management</a>. The committee concluded that supporting healthy eating and drinking, physical activity and weight management in pregnancy can have positive outcomes for the pregnancy and birth but also later on for the child.</p><p>Although there was some moderate quality evidence suggesting an association of low risk for weight loss in pre-pregnancy BMI obesity class I and obesity class II for caesarean birth, the committee discussed that they did not want to recommend weight loss during pregnancy, especially in the first trimester, because it was unclear from the evidence whether the weight loss was intentional or unintentional and there was no evidence of benefit or harm identified for other maternal, neonatal, or fetal outcomes. The committee agreed that people may sometimes lose weight during pregnancy unintentionally, for example, if they change their eating or physical activity patterns. However, the committee agreed that intentional weight loss during pregnancy should be advised against because of potential adverse effects for the unborn baby.</p><p>The committee noted that most of the evidence included in this review was based on Caucasian populations and there was not enough evidence to stratify according to ethnicity, so the committee agreed there was insufficient evidence to make recommendations for different ethnic groups. Additionally, the evidence stratified participants using the standard BMI classification, which is known to not be appropriate for all populations. NHS and NICE recommend different BMI thresholds for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African–Caribbean background because their cardiometabolic risk occurs at a lower BMI level.</p><p>The committee discussed the limited evidence on twin pregnancies and acknowledged that there are provisional IOM/NAM estimated weight change recommendations for this population. The committee discussed that gestational weight change in twin pregnancies is largely due to the weight of the fetuses. However, the committee were aware from their knowledge that these recommendations have very little evidence base and are seldom used, and therefore, they agreed not to make recommendations on this population.</p></div><div id="niceng247er6.s1.1.9.4"><h5>Cost effectiveness and resource use</h5><p>Providing personalised advice during routine antenatal appointments to people who are interested in monitoring their weight change during pregnancy, or if there are concerns about low or excessive weight gain during pregnancy may have important resource implications, comprising health professionals’ additional time spent to offer this advice; the committee also expressed the view that time pressures may become a barrier to implementation. Offering to measure the person’s height and weight and calculate BMI at the first face-to-face antenatal appointment may also have some resource implications regarding health professionals’ time, in settings where this is not current practice, although it reflects current advice (existing NICE recommendation). Discussing the option for referral to a specialist obesity service or a specialist practitioner for anyone with a BMI of over 40 at the booking appointment may also have important resource implications. However, the benefits and cost-savings resulting from the above recommendations are expected to offset, at least partially, the costs of implementing them, by reducing the risk of conditions such as gestational diabetes, pregnancy-related hypertension and preeclampsia for the pregnant person, as well as baby being small or large for gestational age, which have negative implications for the health of pregnant people and their babies and, in turn, increase antenatal and postnatal care costs. Considering a test for gestational diabetes following concerns about excessive weight gain during pregnancy, as well as ensuring routine monitoring of the baby to check if they are potentially small or large for their gestational age if there are concerns about low or excess weight gain during pregnancy, respectively, may also have important resource implications, comprising mainly the ultrasound evaluation of the baby’s size. However, these are likely to be offset, at least partially, by prevention or more timely management of negative outcomes for the pregnant person (such as gestational diabetes) and the baby (such as being small or large for gestational age) further down the care pathway. Offering testing for gestational diabetes to anyone with a BMI of over 30 at the booking appointment is in line with current clinical recommendations and therefore should not lead to a change in practice and resource implications.</p></div><div id="niceng247er6.s1.1.9.5"><h5>Other factors the committee took into account</h5><p>For this review question, the population in the evidence was women and no evidence was identified or reviewed for trans men or non-binary people. The protocol and literature searches were not designed to specifically look for evidence on trans men or non-binary people but they were also not excluded. However, there is a small chance evidence on them may not have been captured, if such evidence exists. In discussing the evidence, the committee considered whether the recommendations could apply to a broader population, and used gender inclusive language to promote equity, respect and effective communication with everyone. Healthcare professionals should use their clinical judgement when implementing the recommendations, taking into account each person’s circumstances, needs and preferences, and ensuring all people are treated with dignity and respect throughout their care.</p></div></div><div id="niceng247er6.s1.1.10"><h4>Recommendations supported by this evidence review</h4><p>This evidence review supports recommendations 1.2.6 to 1.2.8, 1.2.11 and 1.2.14 to 1.2.17. Other evidence supporting some of these recommendations can be found in the evidence review G on interventions for helping to achieve healthy and appropriate weight change during pregnancy.</p></div></div><div id="niceng247er6.s1.rl.r1"><h3>References – included studies</h3><ul class="simple-list"><div id="niceng247er6.s1.rl.r1.1"><h4>Prognostic studies</h4><ul class="simple-list"><li class="half_rhythm"><p><div class="bk_ref" id="niceng247er6.s1.ref1"><p id="p-1629">
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<strong>Beaudrot 2016</strong>
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</p>Beaudrot, M.E.; Elchert, J.A.; DeFranco, E.A. (2016) Influence of gestational weight gain and BMI on caesarean delivery risk in adolescent pregnancies. Journal of Perinatology
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36(8): 612–617
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[<a href="https://pubmed.ncbi.nlm.nih.gov/27054845" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27054845</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="niceng247er6.s1.ref2"><p id="p-1630">
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<strong>Beyerlein 2011</strong>
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</p>Beyerlein, A., Schiessl, B., Lack, N.
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et al. (2011) Associations of gestational weight loss with birth-related outcome: A retrospective cohort study. BJOG: An International Journal of Obstetrics and Gynaecology
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118(1): 55–61
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et al. (2022) Association between gestational weight gain and risk of overweight at 3 years old: The Japan Environment and Children’s Study. Pediatric Obesity [<a href="https://pubmed.ncbi.nlm.nih.gov/36102849" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 36102849</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="niceng247er6.s1.ref37"><p id="p-1665">
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<strong>Voerman 2019</strong>
|
|
</p>Voerman, E., Santos, S., Golab, B.P.
|
|
et al. (2019) Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis. PloS Medicine
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|
16(2): e1002744
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|
[<a href="/pmc/articles/PMC6370184/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6370184</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30742624" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30742624</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="niceng247er6.s1.ref38"><p id="p-1666">
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|
<strong>Whitaker 2022</strong>
|
|
</p>Whitaker, K.M., Ryan, R., Becker, C.
|
|
et al. (2022) Gestational Weight Gain in Twin Pregnancies and Maternal and Child Health: An Updated Systematic Review. Journal of Women’s Health
|
|
31(3): 362–381 [<a href="https://pubmed.ncbi.nlm.nih.gov/33926213" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33926213</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="niceng247er6.s1.ref39"><p id="p-1667">
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|
<strong>Yee 2013</strong>
|
|
</p>Yee, L.M., Cheng, Y.W., Inturrisi, M.
|
|
et al. (2013) Gestational weight loss and perinatal outcomes in overweight and obese women subsequent to diagnosis of gestational diabetes mellitus. Obesity
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|
21(12): e770–e774
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|
[<a href="/pmc/articles/PMC3758809/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3758809</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23613187" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23613187</span></a>]</div></p></li></ul></div><div id="niceng247er6.s1.rl.r1.2"><h4>Other</h4><ul class="simple-list"><li class="half_rhythm"><p><div class="bk_ref" id="niceng247er6.s1.ref40"><p id="p-1668">
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<strong>IOM 2009</strong>
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|
</p>Institute of Medicine (IOM). Weight gain during pregnancy: reexamining the guidelines. Washington, DC: National Academies Press; 2009 [<a href="https://pubmed.ncbi.nlm.nih.gov/20669500" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20669500</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="niceng247er6.s1.ref41"><p id="p-1669">
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|
<strong>Wang 2021</strong>
|
|
</p>Wang
|
|
H, Chen
|
|
Y, Lin
|
|
Y, Abesig
|
|
J, Wu
|
|
I X, Tam
|
|
W
|
|
et al. The methodological quality of individual participant data meta-analysis on intervention effects: systematic review
|
|
BMJ
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|
2021; 373 [<a href="/pmc/articles/PMC8054226/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8054226</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/33875446" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33875446</span></a>]</div></p></li></ul></div></ul></div></div><div id="appendixesappgroup1"><h2 id="_appendixesappgroup1_">Appendices</h2><div id="niceng247er6.appa"><h3>Appendix A. Review protocols</h3><p id="niceng247er6.appa.et1"><a href="/books/NBK612413/bin/niceng247er6-appa-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Review protocol for review question: What gestational weight change is healthy and appropriate during pregnancy?</a><span class="small"> (PDF, 271K)</span></p></div><div id="niceng247er6.appb"><h3>Appendix B. Literature search strategies</h3><p id="niceng247er6.appb.et1"><a href="/books/NBK612413/bin/niceng247er6-appb-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Literature search strategies for review question: What gestational weight change is healthy and appropriate during pregnancy?</a><span class="small"> (PDF, 208K)</span></p></div><div id="niceng247er6.appc"><h3>Appendix C. Prognostic evidence study selection</h3><p id="niceng247er6.appc.et1"><a href="/books/NBK612413/bin/niceng247er6-appc-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Study selection for review question: What gestational weight change is healthy and appropriate during pregnancy?</a><span class="small"> (PDF, 282K)</span></p></div><div id="niceng247er6.appd"><h3>Appendix D. Evidence tables</h3><p id="niceng247er6.appd.et1"><a href="/books/NBK612413/bin/niceng247er6-appd-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Evidence tables for review question: What gestational weight change is healthy and appropriate during pregnancy?</a><span class="small"> (PDF, 1.0M)</span></p></div><div id="niceng247er6.appe"><h3>Appendix E. Forest plots</h3><p id="niceng247er6.appe.et1"><a href="/books/NBK612413/bin/niceng247er6-appe-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Forest plots for review question: What gestational weight change is healthy and appropriate during pregnancy?</a><span class="small"> (PDF, 446K)</span></p></div><div id="niceng247er6.appf"><h3>Appendix F. Adapted GRADE tables</h3><p id="niceng247er6.appf.et1"><a href="/books/NBK612413/bin/niceng247er6-appf-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Adapted GRADE tables for review question: What gestational weight change is healthy and appropriate during pregnancy?</a><span class="small"> (PDF, 952K)</span></p></div><div id="niceng247er6.appg"><h3>Appendix G. Economic evidence study selection</h3><p id="niceng247er6.appg.et1"><a href="/books/NBK612413/bin/niceng247er6-appg-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Study selection for review question: What gestational weight change is healthy and appropriate during pregnancy?</a><span class="small"> (PDF, 118K)</span></p></div><div id="niceng247er6.apph"><h3>Appendix H. Economic evidence tables</h3><div id="niceng247er6.apph.s1"><h4>Economic evidence tables for review question: What gestational weight change is healthy and appropriate during pregnancy?</h4><p>No economic evidence was identified which was applicable to this review question.</p></div></div><div id="niceng247er6.appi"><h3>Appendix I. Economic model</h3><div id="niceng247er6.appi.s1"><h4>Economic model for review question: What gestational weight change is healthy and appropriate during pregnancy?</h4><p>No economic analysis was conducted for this review question.</p></div></div><div id="niceng247er6.appj"><h3>Appendix J. Excluded studies</h3><div id="niceng247er6.appj.s1"><h4>Excluded studies for review question: What gestational weight change is healthy and appropriate during pregnancy?</h4><div id="niceng247er6.appj.s1.1"><h5>Excluded clinical evidence studies</h5><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6appjtab1"><a href="/books/NBK612413/table/niceng247er6.appj.tab1/?report=objectonly" target="object" title="Table 56" class="img_link icnblk_img" rid-ob="figobniceng247er6appjtab1"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.appj.tab1"><a href="/books/NBK612413/table/niceng247er6.appj.tab1/?report=objectonly" target="object" rid-ob="figobniceng247er6appjtab1">Table 56</a></h4><p class="float-caption no_bottom_margin">Excluded studies and reasons for their exclusion. </p></div></div></div><div id="niceng247er6.appj.s1.2"><h5>Excluded economic studies</h5><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng247er6appjtab2"><a href="/books/NBK612413/table/niceng247er6.appj.tab2/?report=objectonly" target="object" title="Table" class="img_link icnblk_img" rid-ob="figobniceng247er6appjtab2"><img class="small-thumb" src="/corehtml/pmc/css/bookshelf/2.26/img/table-icon.gif" alt="Table Icon" /></a><div class="icnblk_cntnt"><h4 id="niceng247er6.appj.tab2"><a href="/books/NBK612413/table/niceng247er6.appj.tab2/?report=objectonly" target="object" rid-ob="figobniceng247er6appjtab2">Table</a></h4><p class="float-caption no_bottom_margin">BMI: body mass index; OECD: Organisation for Economic Co-operation and Development </p></div></div></div></div></div><div id="niceng247er6.appk"><h3>Appendix K. Research recommendations – full details</h3><div id="niceng247er6.appk.s1"><h4>Research recommendations for review question: What gestational weight change is healthy and appropriate during pregnancy?</h4><p>No research recommendations were made for this review question.</p></div></div></div></div><div class="fm-sec"><div><p>Final</p></div><div><p>Evidence reviews underpinning recommendations 1.2.6 to 1.2.8, 1.2.11, and 1.2.14 to 1.2.17 in the NICE guideline</p><p>These evidence reviews were developed by NICE</p></div><div><p><b>Disclaimer</b>: The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The recommendations in this guideline are not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian.</p><p>Local commissioners and/or providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties.</p><p>NICE guidelines cover health and care in England. Decisions on how they apply in other UK countries are made by ministers in the <a href="https://www.gov.wales/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Welsh Government</a>, <a href="http://www.scotland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Scottish Government</a>, and <a href="http://www.northernireland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Northern Ireland Executive</a>. All NICE guidance is subject to regular review and may be updated or withdrawn.</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> © NICE 2025.</div><div class="small"><span class="label">Bookshelf ID: NBK612413</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/40029955" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">40029955</a></span></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article><article data-type="table-wrap" id="figobniceng247er6tab1"><div id="niceng247er6.tab1" class="table"><h3><span class="label">Table 1</span><span class="title">Summary of the protocol (PPO table)</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.tab1_lrgtbl__"><table class="no_bottom_margin"><tbody><tr><th id="hd_b_niceng247er6.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><td headers="hd_b_niceng247er6.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><b>Inclusion:</b>
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<ul><li class="half_rhythm"><div>women during a single or multiple pregnancy</div></li></ul></p>
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<p><b>Exclusion:</b>
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<ul><li class="half_rhythm"><div>pregnant women with pre-existing diabetes</div></li><li class="half_rhythm"><div>women with polycystic ovarian syndrome</div></li></ul></p></td></tr><tr><th id="hd_b_niceng247er6.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Presence or absence of a prognostic risk factor</th><td headers="hd_b_niceng247er6.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gestational weight change, as defined by the study.</td></tr><tr><th id="hd_b_niceng247er6.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcome</th><td headers="hd_b_niceng247er6.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><b>Critical</b></p>
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<ul><li class="half_rhythm"><div>maternal outcomes
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|
<ul class="circle"><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>hypertensive disorders of pregnancy (preeclampsia and gestational hypertension)</div></li><li class="half_rhythm"><div>gestational diabetes</div></li></ul></div></li><li class="half_rhythm"><div>fetal/neonatal outcomes:
|
|
<ul class="circle"><li class="half_rhythm"><div>SGA <10<sup>th</sup> centile</div></li><li class="half_rhythm"><div>LGA >90<sup>th</sup> centile</div></li></ul></div></li><li class="half_rhythm"><div>childhood outcomes (after 2 years)
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<ul class="circle"><li class="half_rhythm"><div>overweight/obesity</div></li></ul></div></li></ul>
|
|
<p><b>Important</b></p>
|
|
<ul><li class="half_rhythm"><div>maternal outcomes:
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|
<ul class="circle"><li class="half_rhythm"><div>health related quality of life as measured by a validated tool, for example HRQoL.</div></li></ul></div></li></ul></td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">HRQoL: health related quality of life; LGA: large for gestational age; SGA: small for gestational age</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6tab2"><div id="niceng247er6.tab2" class="table"><h3><span class="label">Table 2</span><span class="title">Summary of included studies</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.tab2_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><th id="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Risk factor</th><th id="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Covariates adjusted in analysis</th><th id="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes</th></tr></thead><tbody><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref1" rid="niceng247er6.s1.ref1">Beaudrot 2016</a></p>
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<p>Retrospective cohort study</p>
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<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=237717 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>:
|
|
<ul><li class="half_rhythm"><div><15 years: 23.4 (5.0)</div></li><li class="half_rhythm"><div>15-17 years: 23.6 (4.9)</div></li><li class="half_rhythm"><div>18-19 years: 24.6 (5.7)</div></li><li class="half_rhythm"><div>20-34 years: 25.9 (6.4)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>lost weight</div></li><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul>
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Referent: appropriate weight gain in 20-34 year olds.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal race</div></li><li class="half_rhythm"><div>smoking status</div></li><li class="half_rhythm"><div>labour induction.</div></li></ul></td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref2" rid="niceng247er6.s1.ref2">Beyerlein 2011</a></p>
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<p>Retrospective cohort study</p>
|
|
<p>Germany</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=445323 women</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>gestational weight loss (GWL): 30.2 (NR)</div></li><li class="half_rhythm"><div>non-excessive gestational weight gain (NEGWG): 30.6 (NR)</div></li><li class="half_rhythm"><div>excessive gestational weight gain (EGWG): 29.7 (NR)</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight
|
|
<ul class="circle"><li class="half_rhythm"><div>GWL: 19 (0.54)</div></li><li class="half_rhythm"><div>NEGWG: 26173 (5.92)</div></li><li class="half_rhythm"><div>EGWG: 4328 (1.64)</div></li></ul></div></li><li class="half_rhythm"><div>normal weight
|
|
<ul class="circle"><li class="half_rhythm"><div>GWL: 480 (13.63)</div></li><li class="half_rhythm"><div>NEGWG: 331439 (75.02)</div></li><li class="half_rhythm"><div>EGWG: 128673 (48.69)</div></li></ul></div></li><li class="half_rhythm"><div>overweight
|
|
<ul class="circle"><li class="half_rhythm"><div>GWL: 808 (22.95)</div></li><li class="half_rhythm"><div>NEGWG: 54512 (12.34)</div></li><li class="half_rhythm"><div>EGWG: 90015 (34.06)</div></li></ul></div></li><li class="half_rhythm"><div>obese class I
|
|
<ul class="circle"><li class="half_rhythm"><div>GWL: 889 (25.25)</div></li><li class="half_rhythm"><div>NEGWG: 18308 (4.14)</div></li><li class="half_rhythm"><div>EGWG: 30043 (11.37)</div></li></ul></div></li><li class="half_rhythm"><div>obese class II
|
|
<ul class="circle"><li class="half_rhythm"><div>GWL: 688 (19.54)</div></li><li class="half_rhythm"><div>NEGWG: 7756 (1.76)</div></li><li class="half_rhythm"><div>EGWG: 8229 (3.11)</div></li></ul></div></li><li class="half_rhythm"><div>obese class III
|
|
<ul class="circle"><li class="half_rhythm"><div>GWL: 637 (18.09)</div></li><li class="half_rhythm"><div>NEGWG: 3614 (0.82)</div></li><li class="half_rhythm"><div>EGWG: 2964 (1.12)</div></li></ul></div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>weight loss.</div></li></ul></p>
|
|
<p>Referent: non-excessive weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and at booking.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>gestational and pre-gestational diabetes</div></li><li class="half_rhythm"><div>smoking in pregnancy</div></li><li class="half_rhythm"><div>offspring’s sex</div></li><li class="half_rhythm"><div>parity and maternal age</div></li><li class="half_rhythm"><div>preterm delivery.</div></li></ul>
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|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref3" rid="niceng247er6.s1.ref3">Blomberg 2011</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Sweden</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=46595 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>weight loss</div></li><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b>
|
|
<ul><li class="half_rhythm"><div>Difference between weight prior to birth and at 1st visit.</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>smoking.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref4" rid="niceng247er6.s1.ref4">Breckenkamp 2019</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>Germany</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=NR</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>non-immigrants: 30.9 (NR)</div></li><li class="half_rhythm"><div>first-generation immigrant women:
|
|
<ul class="circle"><li class="half_rhythm"><div>low and lower middle-income countries: 30.2 (5.6)</div></li><li class="half_rhythm"><div>upper middle-income countries: 29.5 (5.8)</div></li><li class="half_rhythm"><div>high-income countries: 31.0 (5.4)</div></li></ul></div></li><li class="half_rhythm"><div>second-generation immigrant women: 27.6 (5.2)</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup> (%):
|
|
<ul><li class="half_rhythm"><div>BMI <18.5
|
|
<ul class="circle"><li class="half_rhythm"><div>non-immigrants: 3.9</div></li><li class="half_rhythm"><div>first-generation immigrant women:
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">low and lower middle-income countries: 3.3</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">upper middle-income countries: 5.1</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">high-income countries: 3.5</p></dd></dl></dl></div></li><li class="half_rhythm"><div>second-generation immigrant women: 3.7</div></li></ul></div></li><li class="half_rhythm"><div>BMI <25
|
|
<ul class="circle"><li class="half_rhythm"><div>non-immigrants: 64.8</div></li><li class="half_rhythm"><div>first-generation immigrant women
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">low and lower middle-income countries: 53.0</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">upper middle-income countries: 50.8</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">high-income countries: 71.8</p></dd></dl></dl></div></li><li class="half_rhythm"><div>second-generation immigrant women: 55.3</div></li></ul></div></li><li class="half_rhythm"><div>BMI <30
|
|
<ul class="circle"><li class="half_rhythm"><div>non-immigrants: 20.7</div></li><li class="half_rhythm"><div>first-generation immigrant women
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">low and lower middle-income countries: 29.9</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">upper middle-income countries: 31.9</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">high-income countries: 15.5</p></dd></dl></dl></div></li><li class="half_rhythm"><div>second-generation immigrant women: 25.8</div></li></ul></div></li><li class="half_rhythm"><div>BMI ≥30
|
|
<ul class="circle"><li class="half_rhythm"><div>non-immigrants: 10.6</div></li><li class="half_rhythm"><div>first-generation immigrant women
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">low and lower middle-income countries: 13.8</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">upper middle-income countries: 12.2</p></dd></dl><dl class="bkr_refwrap"><dt>–</dt><dd><p class="no_top_margin">high-income countries: 9.2</p></dd></dl></dl></div></li><li class="half_rhythm"><div>second-generation immigrant women: 15.3</div></li></ul></div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and at 1st prenatal check-up.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>parity.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref5" rid="niceng247er6.s1.ref5">Cedergren 2006</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>Sweden</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=246324 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and at 1<sup>st</sup> visit.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>smoking in early pregnancy</div></li><li class="half_rhythm"><div>year of birth.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref6" rid="niceng247er6.s1.ref6">Chen CN 2020</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>Taiwan</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=19052 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 3851 (20.2)</div></li><li class="half_rhythm"><div>normal: 13333 (70.0)</div></li><li class="half_rhythm"><div>overweight: 1524 (8.0)</div></li><li class="half_rhythm"><div>obese: 344 (1.8)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>infant sex</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>maternal education</div></li><li class="half_rhythm"><div>maternal immigration status</div></li><li class="half_rhythm"><div>family monthly income</div></li><li class="half_rhythm"><div>urbanicity of living area</div></li><li class="half_rhythm"><div>smoking during pregnancy.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>gestational hypertension</div></li><li class="half_rhythm"><div>preeclampsia</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref7" rid="niceng247er6.s1.ref7">Chen L 2020</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Taiwan</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=NR</p>
|
|
<p>Median age (years):
|
|
<ul><li class="half_rhythm"><div>normal pregnancy: 34.0</div></li><li class="half_rhythm"><div>preeclampsia: 35.0</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, median (IQR):
|
|
<ul><li class="half_rhythm"><div>normal pregnancy: 22.0 (4.3)</div></li><li class="half_rhythm"><div>preeclampsia: 24.0 (8.0)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>>20kg weight gain.</div></li></ul></p>
|
|
<p>Referent: ≤20kg weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>endocrine parameters</div></li><li class="half_rhythm"><div>mother’s age</div></li><li class="half_rhythm"><div>age of the male partner</div></li><li class="half_rhythm"><div>BMI</div></li><li class="half_rhythm"><div>infertility diagnosis</div></li><li class="half_rhythm"><div>ovarian stimulation protocol</div></li><li class="half_rhythm"><div>duration of ovarian stimulation</div></li><li class="half_rhythm"><div>maximal endometrial thickness</div></li><li class="half_rhythm"><div>number oocytes retrieved</div></li><li class="half_rhythm"><div>number of embryos transferred</div></li><li class="half_rhythm"><div>use of ICSI</div></li><li class="half_rhythm"><div>use of blastocyst-stage ET</div></li><li class="half_rhythm"><div>occurrence of multiple pregnancies</div></li><li class="half_rhythm"><div>pregnancy weight gain.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>preeclampsia.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref8" rid="niceng247er6.s1.ref8">Chen-Xu 2022</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Portugal</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=13467 women</p>
|
|
<p>Mean (SD) age (years): 33.3 (NR)</p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>: 27.0 (5.8)</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth/last appointment before birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>number of previous abortions/deliveries</div></li><li class="half_rhythm"><div>first degree family history of diabetes</div></li><li class="half_rhythm"><div>previous macrosomia</div></li><li class="half_rhythm"><div>fasting glucose</div></li><li class="half_rhythm"><div>weeks between diagnosis and first hospital appointment</div></li><li class="half_rhythm"><div>GD treatment</div></li><li class="half_rhythm"><div>BMI category</div></li><li class="half_rhythm"><div>week of delivery.</div></li></ul></td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>gestational hypertension</div></li><li class="half_rhythm"><div>preeclampsia</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>SGA</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref9" rid="niceng247er6.s1.ref9">Chuang 2022</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Taiwan</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=5529 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 1177 (14.1)</div></li><li class="half_rhythm"><div>normal: 6217 (74.4)</div></li><li class="half_rhythm"><div>overweight/obese: 958 (11.5)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>excessive weight gain
|
|
<ul class="circle"><li class="half_rhythm"><div>first trimester</div></li><li class="half_rhythm"><div>second trimester</div></li><li class="half_rhythm"><div>before GDM test.</div></li></ul></div></li></ul></p>
|
|
<p>Referent: NR</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>First trimester, second trimester, before GDM test.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age at delivery (<20, 20–34, and >34 years)</div></li><li class="half_rhythm"><div>primiparity</div></li><li class="half_rhythm"><div>a prior history of assisted or spontaneous abortion</div></li><li class="half_rhythm"><div>preterm delivery</div></li><li class="half_rhythm"><div>stillbirth (>20 weeks of gestation)</div></li><li class="half_rhythm"><div>a family history of type 2 diabetes mellitus (first- and second-degree relatives)</div></li><li class="half_rhythm"><div>conception by assisted reproductive technology (ART)</div></li><li class="half_rhythm"><div>cigarette smoking during pregnancy</div></li><li class="half_rhythm"><div>uterine fibroids</div></li><li class="half_rhythm"><div>maternal diseases such as chronic hypertension, preeclampsia, hypothyroidism, and hyperthyroidism.</div></li></ul></td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>gestational diabetes.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref10" rid="niceng247er6.s1.ref10">Di Benedetto 2012</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Italy</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=2225 women</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>underweight: 28.6 (NR)</div></li><li class="half_rhythm"><div>normal weight: 29.5 (NR)</div></li><li class="half_rhythm"><div>overweight: 30.3 (NR)</div></li><li class="half_rhythm"><div>obese: 30.3 (NR)</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 284 (2.7)</div></li><li class="half_rhythm"><div>normal: 1430 (64.3)</div></li><li class="half_rhythm"><div>overweight: 336 (15.1)</div></li><li class="half_rhythm"><div>obese: 175 (7.9)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>gestation age at delivery</div></li><li class="half_rhythm"><div>glycaemia.</div></li></ul></td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref11" rid="niceng247er6.s1.ref11">Enomoto 2016</a></p>
|
|
<p>Prospective and retrospective cohort study</p>
|
|
<p>Japan</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=97157 women</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>underweight: 30.88 (NR)</div></li><li class="half_rhythm"><div>normal weight: 31.95 (NR)</div></li><li class="half_rhythm"><div>overweight: 32.46 (NR)</div></li><li class="half_rhythm"><div>obese: 32.04 (NR)</div></li></ul></p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>:
|
|
<ul><li class="half_rhythm"><div>underweight: 17.59 (0.75)</div></li><li class="half_rhythm"><div>normal weight: 20.9 (1.63)</div></li><li class="half_rhythm"><div>overweight: 26.93 (1.39)</div></li><li class="half_rhythm"><div>obese: 33.65 (3.4)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>maternal height</div></li><li class="half_rhythm"><div>parity.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>gestational hypertension</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>SGA</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref12" rid="niceng247er6.s1.ref12">Flick 2010</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=NR</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>BMI 30-35.9: 28.0 (NR)</div></li><li class="half_rhythm"><div>BMI 36-39.9: 28.3 (NR)</div></li><li class="half_rhythm"><div>BMI ≥40: 28.0 (NR)</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>weight loss</div></li><li class="half_rhythm"><div>weight gain of up to 14.9lbs</div></li><li class="half_rhythm"><div>weight gain of 25lbs.</div></li></ul></p>
|
|
<p>Referent: weight gain of 15 to 24.9lbs.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>race/ethnicity</div></li><li class="half_rhythm"><div>trimester at first prenatal visit</div></li><li class="half_rhythm"><div>previous CD, previous preterm delivery</div></li><li class="half_rhythm"><div>chronic hypertension</div></li><li class="half_rhythm"><div>pregestational diabetes.</div></li></ul></td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref13" rid="niceng247er6.s1.ref13">Gaillard 2013</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>The Netherlands</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=NR</p>
|
|
<p>Median age, years (90% range): 30.3 (20.4 to 37.9)</p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>: 23.6 (4.4)</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate/inadequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>educational level</div></li><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>ethnicity</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>folic acid supplement use</div></li><li class="half_rhythm"><div>smoking habits</div></li><li class="half_rhythm"><div>alcohol consumption.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref14" rid="niceng247er6.s1.ref14">Gante 2015</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Portugal</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=1806 women</p>
|
|
<p>Mean (SD) age (years): 33.1 (NR)</p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>: 34.7 (4.2)</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b> NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>pre-pregnancy BMI</div></li><li class="half_rhythm"><div>use of insulin</div></li><li class="half_rhythm"><div>gestational age at delivery</div></li><li class="half_rhythm"><div>birthweight.</div></li></ul></td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref15" rid="niceng247er6.s1.ref15">Gavard 2017</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=12117 women</p>
|
|
<p>Mean (SD) age (years): NR (SD)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b> NR</p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>race</div></li><li class="half_rhythm"><div>education</div></li><li class="half_rhythm"><div>socioeconomic status</div></li><li class="half_rhythm"><div>smoking</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>diabetes</div></li><li class="half_rhythm"><div>adequacy of prenatal care</div></li><li class="half_rhythm"><div>sex of infant</div></li><li class="half_rhythm"><div>gestational age at delivery.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref16" rid="niceng247er6.s1.ref16">Gawade 2011</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=2495 women</p>
|
|
<p>Mean (SD) age (years): NR (SD)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div><18.5: 77 (3.1)</div></li><li class="half_rhythm"><div>18.5-24.9: 1035 (41.5)</div></li><li class="half_rhythm"><div>25-29.9: 684 (27.4)</div></li><li class="half_rhythm"><div>≥30: 699 (28.0)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>gestational weight gain</div></li><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>birthweight</div></li><li class="half_rhythm"><div>gestational age</div></li><li class="half_rhythm"><div>pre-pregnancy BMI</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>bishop score</div></li><li class="half_rhythm"><div>infant gender.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref17" rid="niceng247er6.s1.ref17">Graham 2014</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=2157 women</p>
|
|
<p>Mean (SD) age (years): NR (SD)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div><18.5: 255 (12.83)</div></li><li class="half_rhythm"><div>18.5–24.9: 1085 (48.78)</div></li><li class="half_rhythm"><div>25.0–29.9: 432 (21.00)</div></li><li class="half_rhythm"><div>≥30.0: 385 (17.39)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>race/ethnicity</div></li><li class="half_rhythm"><div>live births</div></li><li class="half_rhythm"><div>household income</div></li><li class="half_rhythm"><div>education.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref18" rid="niceng247er6.s1.ref18">Haile 2019</a></p><p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=2107 women</p><p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 1007 (47.8)</div></li><li class="half_rhythm"><div>normal: 99 (4.7)</div></li><li class="half_rhythm"><div>overweight: 536 (25.4)</div></li><li class="half_rhythm"><div>obese: 465 (22.1)</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>education</div></li><li class="half_rhythm"><div>marital status</div></li><li class="half_rhythm"><div>pre-pregnancy body mass index</div></li><li class="half_rhythm"><div>race/ethnicity</div></li><li class="half_rhythm"><div>poverty-income ratio</div></li><li class="half_rhythm"><div>gestational age</div></li><li class="half_rhythm"><div>previous birth experience</div></li><li class="half_rhythm"><div>gestational diabetes mellitus</div></li><li class="half_rhythm"><div>macrosomia</div></li><li class="half_rhythm"><div>type of birth attendant.</div></li></ul></td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref19" rid="niceng247er6.s1.ref19">Harper 2011</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=76675 women</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>underweight: 17.49 (NR)</div></li><li class="half_rhythm"><div>normal weight: 17.55 (NR)</div></li><li class="half_rhythm"><div>overweight: 17.73 (NR)</div></li><li class="half_rhythm"><div>obese: 17.96 (NR)</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>maternal race</div></li><li class="half_rhythm"><div>tobacco use</div></li><li class="half_rhythm"><div>alcohol use</div></li><li class="half_rhythm"><div>a composite maternal medical risk factor (includes chronic hypertension, diabetes, and renal disease), Medicaid, and the Kotel chuck prenatal care index.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref20" rid="niceng247er6.s1.ref20">Haugen 2014</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>Norway</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=56071 women</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>nulliparous: 28.4 (NR)</div></li><li class="half_rhythm"><div>parous: 31.8 (NR)</div></li></ul></p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>:
|
|
<ul><li class="half_rhythm"><div>nulliparous: 23.7 (4.1)</div></li><li class="half_rhythm"><div>parous: 24.2 (4.2)</div></li></ul></p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight 6 months postpartum and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age at delivery</div></li><li class="half_rhythm"><div>maternal height</div></li><li class="half_rhythm"><div>maternal education level</div></li><li class="half_rhythm"><div>smoking in pregnancy</div></li><li class="half_rhythm"><div>gestational length</div></li><li class="half_rhythm"><div>diabetic conditions.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>
|
|
<a class="bibr" href="#niceng247er6.s1.ref21" rid="niceng247er6.s1.ref21">Hautier 2022</a>
|
|
</p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>France</p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=340 women</p><p>Median (IQR) age, years:
|
|
<ul><li class="half_rhythm"><div>BMI <18.5: 28 (27 to 34)</div></li><li class="half_rhythm"><div>BMI 18.5-24: 30 (25 to 32)</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>BMI <18.5 kg/m<sup>2</sup></div></li><li class="half_rhythm"><div>smoking</div></li><li class="half_rhythm"><div>parity.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>SGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref22" rid="niceng247er6.s1.ref22">Hung 2016</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Taiwan</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=10970 women</p>
|
|
<p>Age, years, n:
|
|
<ul><li class="half_rhythm"><div><20: 18</div></li><li class="half_rhythm"><div>20-34: 7086</div></li><li class="half_rhythm"><div>>34: 3869</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age at delivery</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>prior fetal death</div></li><li class="half_rhythm"><div>prior preterm birth</div></li><li class="half_rhythm"><div>conception methods</div></li><li class="half_rhythm"><div>genetic amniocentesis</div></li><li class="half_rhythm"><div>smoking during pregnancy</div></li><li class="half_rhythm"><div>group B streptococcal colonization at the genitorectal tract</div></li><li class="half_rhythm"><div>fetal sex</div></li><li class="half_rhythm"><div>intrapartum epidural analgesia.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>preeclampsia</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>SGA</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref23" rid="niceng247er6.s1.ref23">Kiefer 2022</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=8322 women</p>
|
|
<p>Mean (SD) age (years): 30.6 (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 161 (1.9)</div></li><li class="half_rhythm"><div>normal: 2558 (30.7)</div></li><li class="half_rhythm"><div>overweight: 2188 (26.3)</div></li><li class="half_rhythm"><div>obesity class I: 1625 (19.5)</div></li><li class="half_rhythm"><div>obesity class II: 936 (11.3)</div></li><li class="half_rhythm"><div>obesity class III: 854 (10.3)</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and at 1<sup>st</sup> prenatal checkup.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>race</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>history of caesarean delivery</div></li><li class="half_rhythm"><div>chronic hypertension</div></li><li class="half_rhythm"><div>tobacco use</div></li><li class="half_rhythm"><div>delivery year</div></li><li class="half_rhythm"><div>gestational age at birth.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref24" rid="niceng247er6.s1.ref24">Kominiarek 2013</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=20950 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div><0kg weight gain</div></li><li class="half_rhythm"><div>0 to 4.9kg weight gain</div></li><li class="half_rhythm"><div>>9kg weight gain.</div></li></ul></p>
|
|
<p>Referent: 5 to 9kg weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>race/ethnicity</div></li><li class="half_rhythm"><div>marital status</div></li><li class="half_rhythm"><div>insurance</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>smoking</div></li><li class="half_rhythm"><div>gestational age.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref25" rid="niceng247er6.s1.ref25">Langford 2011</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=34143 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref26" rid="niceng247er6.s1.ref26">Lautredou 2022</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>France</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=3162 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 247 (6.9)</div></li><li class="half_rhythm"><div>normal: 1932 (53.7)</div></li><li class="half_rhythm"><div>overweight: 583 (18.4)</div></li><li class="half_rhythm"><div>obese: 400 (12.7)</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight at last appointment before birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>geographical origin</div></li><li class="half_rhythm"><div>tobacco use</div></li><li class="half_rhythm"><div>gestational age</div></li><li class="half_rhythm"><div>preexisting diabetes</div></li><li class="half_rhythm"><div>preexisting chronic hypertension.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>gestational hypertension</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>LGA.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref27" rid="niceng247er6.s1.ref27">Liang 2021</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Taiwan</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=2210 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 223 (10.1)</div></li><li class="half_rhythm"><div>normal: 1591 (71.2)</div></li><li class="half_rhythm"><div>overweight: 305 (13.8)</div></li><li class="half_rhythm"><div>obese: 91 (4.2)</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>education</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>preterm birth</div></li><li class="half_rhythm"><div>fetal head circumference.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref28" rid="niceng247er6.s1.ref28">Lipworth 2022</a></p>
|
|
<p>Systematic review</p>
|
|
<p>USA & Europe</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=13485 women in 14 studies</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n:</p>
|
|
<p><b>Algeri 2018: n=175</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 134</div></li><li class="half_rhythm"><div>overweight: 30</div></li><li class="half_rhythm"><div>obese: 11</div></li></ul></p>
|
|
<p><a class="bibr" href="#niceng247er6.appj.ref54" rid="niceng247er6.appj.ref54">Fox 2010</a><b>: n=297</b>
|
|
<ul><li class="half_rhythm"><div>underweight: n=16</div></li><li class="half_rhythm"><div>normal weight: n=201</div></li><li class="half_rhythm"><div>overweight: n=51</div></li><li class="half_rhythm"><div>obese: n=29</div></li></ul></p>
|
|
<p><b>Fox 2011: n=170</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 117</div></li><li class="half_rhythm"><div>overweight: NR</div></li><li class="half_rhythm"><div>obese: NR</div></li></ul></p>
|
|
<p><a class="bibr" href="#niceng247er6.appj.ref57" rid="niceng247er6.appj.ref57">Gavard 2014</a><b>: n=831</b>
|
|
<ul><li class="half_rhythm"><div>obese: n=831
|
|
<ul class="circle"><li class="half_rhythm"><div>obese I: 405</div></li><li class="half_rhythm"><div>obese II: 223</div></li><li class="half_rhythm"><div>obese III: 203</div></li></ul></div></li></ul></p>
|
|
<p><b>Gonzalez-Quintero 2012: n=5129</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 2875</div></li><li class="half_rhythm"><div>overweight: 1241</div></li><li class="half_rhythm"><div>obese: 1013</div></li></ul></p>
|
|
<p><b>Kosinska-Kaczynska 2017: n=201</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 201</div></li></ul></p>
|
|
<p><b>Lal 2015: n=2654</b>
|
|
<ul><li class="half_rhythm"><div>underweight/normal weight: 1497</div></li><li class="half_rhythm"><div>overweight: 606</div></li><li class="half_rhythm"><div>obese: 551</div></li></ul></p>
|
|
<p><b>Liu 2019: n=252</b>
|
|
<ul><li class="half_rhythm"><div>overweight: 162</div></li><li class="half_rhythm"><div>obese: 90</div></li></ul></p>
|
|
<p><b>Liu 2020: n=609</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 609</div></li></ul></p>
|
|
<p><b>Lutsiv 2017: n=741</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 350</div></li><li class="half_rhythm"><div>overweight: 196</div></li><li class="half_rhythm"><div>obese: 195</div></li></ul></p>
|
|
<p><a class="bibr" href="#niceng247er6.appj.ref115" rid="niceng247er6.appj.ref115">Pecheux 2019</a><b>: n=878</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 621</div></li><li class="half_rhythm"><div>overweight: 168</div></li><li class="half_rhythm"><div>obese: 88</div></li></ul></p>
|
|
<p><b>Pettit 2015: n=489</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 293</div></li><li class="half_rhythm"><div>overweight: 102</div></li><li class="half_rhythm"><div>obese: 94</div></li></ul></p>
|
|
<p><b>Pettit 2016: n=489</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 247</div></li><li class="half_rhythm"><div>overweight: 85</div></li><li class="half_rhythm"><div>obese: 69</div></li></ul></p>
|
|
<p><b>Shamshirsaz 2014: n=570</b>
|
|
<ul><li class="half_rhythm"><div>normal weight: 286</div></li><li class="half_rhythm"><div>overweight: 161</div></li><li class="half_rhythm"><div>obese: 123</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal pre-pregnancy body mass index (BMI)</div></li><li class="half_rhythm"><div>chronicity</div></li><li class="half_rhythm"><div>artificial reproductive therapies.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>preeclampsia</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>SGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref29" rid="niceng247er6.s1.ref29">McCurdy 2022</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=55275 women</p>
|
|
<p>Mean (SD) age (years): NR (SD)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div><18.5: 2440 (4.2)</div></li><li class="half_rhythm"><div>18.5-24.9: 27515 (47.6)</div></li><li class="half_rhythm"><div>25-29.9: 14151 (24.5)</div></li><li class="half_rhythm"><div>30-34.9: 7482 (12.9)</div></li><li class="half_rhythm"><div>35-39.9: 3555 (6.1)</div></li><li class="half_rhythm"><div>≥40: 2669 (4.6)</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div><11lbs weight gain</div></li><li class="half_rhythm"><div>>20lbs weight gain.</div></li></ul></p>
|
|
<p>Referent: 11 to 20lbs weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>race</div></li><li class="half_rhythm"><div>ethnicity</div></li><li class="half_rhythm"><div>educational level</div></li><li class="half_rhythm"><div>marital status</div></li><li class="half_rhythm"><div>household income</div></li><li class="half_rhythm"><div>live birth order</div></li><li class="half_rhythm"><div>alcohol use</div></li><li class="half_rhythm"><div>gestational age</div></li><li class="half_rhythm"><div>intendedness of pregnancy</div></li><li class="half_rhythm"><div>infant birth weight</div></li><li class="half_rhythm"><div>physical activity during pregnancy</div></li><li class="half_rhythm"><div>comprehensiveness of prenatal care.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref30" rid="niceng247er6.s1.ref30">Morken 2013</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>Norway</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=50416 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div><8kg weight gain</div></li><li class="half_rhythm"><div>≥16kg weight gain.</div></li></ul></p>
|
|
<p>Referent: 8 to 15.9kg weight gain.</p><p><b>Gestational weight change definition:</b></p><p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>smoking</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>BMI category.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref31" rid="niceng247er6.s1.ref31">Nohr 2008</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Denmark</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=60952 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 2679 (4.4)</div></li><li class="half_rhythm"><div>normal weight: 41589 (68.3)</div></li><li class="half_rhythm"><div>overweight: 11874 (19.5)</div></li><li class="half_rhythm"><div>obese: 4810 (7.9)</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div><10kg weight gain</div></li><li class="half_rhythm"><div>16 to 19kg weight gain</div></li><li class="half_rhythm"><div>≥20kg weight gain.</div></li></ul></p>
|
|
<p>Referent: 10 to 15kg weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight 6 months postpartum and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>age</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>height</div></li><li class="half_rhythm"><div>smoking</div></li><li class="half_rhythm"><div>alcohol consumption</div></li><li class="half_rhythm"><div>social status</div></li><li class="half_rhythm"><div>exercise</div></li><li class="half_rhythm"><div>gestational age (in days)</div></li><li class="half_rhythm"><div>birth weight.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref32" rid="niceng247er6.s1.ref32">Park 2011</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=570672 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>maternal race/ethnicity</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>gestational age</div></li><li class="half_rhythm"><div>maternal education attainment</div></li><li class="half_rhythm"><div>smoking status during pregnancy</div></li><li class="half_rhythm"><div>WIC program participation</div></li><li class="half_rhythm"><div>total number of prenatal visits</div></li><li class="half_rhythm"><div>sex of infant</div></li><li class="half_rhythm"><div>infant birth year.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>SGA</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref33" rid="niceng247er6.s1.ref33">Premru-Srsen 2019</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>Slovakia</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=98604 women</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>women without PE: 30.2 (NR)</div></li><li class="half_rhythm"><div>women with PE: 30.3 (NR)</div></li></ul></p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>:
|
|
<ul><li class="half_rhythm"><div>women without PE: 23.7 (4.5)</div></li><li class="half_rhythm"><div>women with PE: 26.6 (5.8)</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>6.7 to 10kg weight gain</div></li><li class="half_rhythm"><div><0.5 to 6.9kg weight gain</div></li><li class="half_rhythm"><div>13.7 to 29kg weight gain</div></li><li class="half_rhythm"><div>>24.6 to ≥29.1kg weight gain</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between last recorded weight before birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>preventive treatment with low-dose Aspirin</div></li><li class="half_rhythm"><div>smoking</div></li><li class="half_rhythm"><div>pre-pregnancy diabetes mellitus</div></li><li class="half_rhythm"><div>pre-pregnancy hypertension</div></li><li class="half_rhythm"><div>pre-pregnancy BMI.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>preeclampsia.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a></p>
|
|
<p>IPD</p>
|
|
<p>Birth cohorts from Europe, North America, and Oceania</p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=265270 women from 39 birth cohorts</p>
|
|
<p>Median age (years): 30</p>
|
|
<p>Maternal pre-pregnancy BMI, kg/m<sup>2</sup>, n (%):
|
|
<ul><li class="half_rhythm"><div>underweight: 9065</div></li><li class="half_rhythm"><div>normal weight: 148697</div></li><li class="half_rhythm"><div>overweight: 42678</div></li><li class="half_rhythm"><div>obese I: 13084</div></li><li class="half_rhythm"><div>obese II: 3597</div></li><li class="half_rhythm"><div>obese III: 1095</div></li></ul></p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>low weight gain</div></li><li class="half_rhythm"><div>medium weight gain</div></li><li class="half_rhythm"><div>high weight gain.</div></li></ul></p>
|
|
<p>Referent: medium weight gain in women with normal BMI pre-pregnancy.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between last recorded weight before birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>educational level</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>smoking habits during pregnancy.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>gestational hypertension</div></li><li class="half_rhythm"><div>preeclampsia</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>SGA</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref35" rid="niceng247er6.s1.ref35">Simko 2019</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>Slovakia</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=7102 women</p>
|
|
<p>Mean (SD) age (years):
|
|
<ul><li class="half_rhythm"><div>underweight: 17.7 (NR)</div></li><li class="half_rhythm"><div>normal weight: 21.2 (NR)</div></li><li class="half_rhythm"><div>overweight: 26.8 (NR)</div></li><li class="half_rhythm"><div>obese: 34.9 (NR)</div></li></ul></p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>gestational age</div></li><li class="half_rhythm"><div>maternal BMI</div></li><li class="half_rhythm"><div>smoking.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref36" rid="niceng247er6.s1.ref36">Tanigawa 2022</a></p>
|
|
<p>Prospective cohort study</p>
|
|
<p>Japan</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=64336 women</p>
|
|
<p>Mean (SD) age (years): 31.54 (NR)</p>
|
|
<p>Mean (SD) maternal pre-pregnancy BMI, kg/m<sup>2</sup>: 21.12 (NR)</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain in women with normal BMI pre-pregnancy.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>maternal BMI before pregnancy</div></li><li class="half_rhythm"><div>maternal education levels</div></li><li class="half_rhythm"><div>smoking during pregnancy</div></li><li class="half_rhythm"><div>the frequency of maternal passive smoking during pregnancy</div></li><li class="half_rhythm"><div>drinking during pregnancy</div></li><li class="half_rhythm"><div>household income during pregnancy</div></li><li class="half_rhythm"><div>occupation during pregnancy</div></li><li class="half_rhythm"><div>marital status during pregnancy</div></li><li class="half_rhythm"><div>number of children during pregnancy</div></li><li class="half_rhythm"><div>a history of hypertensive disorder of pregnancy</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>offspring sex</div></li><li class="half_rhythm"><div>gestational age.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>childhood overweight/obesity.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref37" rid="niceng247er6.s1.ref37">Voerman 2019</a></p>
|
|
<p>IPD</p>
|
|
<p>Cohorts from Europe, North America, and Oceania</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=181678 women from 37 pregnancy and birth cohorts</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Median (95% range) maternal pre-pregnancy BMI, kg/m<sup>2</sup>: 22.7 (18.1 to 34.3)</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between last recorded weight before birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>maternal educational level</div></li><li class="half_rhythm"><div>maternal ethnicity</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>maternal smoking during pregnancy.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>childhood overweight/obesity.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a></p>
|
|
<p>Systematic review</p>
|
|
<p>Japan, USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=NR</p><p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>inadequate weight gain</div></li><li class="half_rhythm"><div>excessive weight gain.</div></li></ul></p>
|
|
<p>Referent: adequate weight gain.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight prior to birth and pre-pregnancy body weight.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>pre-existing diabetes or hypertension</div></li><li class="half_rhythm"><div>pre-pregnancy BMI</div></li><li class="half_rhythm"><div>chronicity</div></li><li class="half_rhythm"><div>gestational age at delivery</div></li><li class="half_rhythm"><div>infant sex</div></li><li class="half_rhythm"><div>race/ethnicity</div></li><li class="half_rhythm"><div>height</div></li><li class="half_rhythm"><div>smoking</div></li><li class="half_rhythm"><div>employment and student status</div></li><li class="half_rhythm"><div>marital status</div></li><li class="half_rhythm"><div>insurance</div></li><li class="half_rhythm"><div>education</div></li><li class="half_rhythm"><div>fertility treatment</div></li><li class="half_rhythm"><div>fetal sex of the twin pair</div></li><li class="half_rhythm"><div>cerclage</div></li><li class="half_rhythm"><div>prior preterm birth</div></li><li class="half_rhythm"><div>payer status</div></li><li class="half_rhythm"><div>diabetes</div></li><li class="half_rhythm"><div>mode of conception</div></li><li class="half_rhythm"><div>gestational age.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth</div></li><li class="half_rhythm"><div>gestational hypertension</div></li><li class="half_rhythm"><div>preeclampsia</div></li><li class="half_rhythm"><div>gestational diabetes</div></li><li class="half_rhythm"><div>SGA</div></li><li class="half_rhythm"><div>LGA.</div></li></ul>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p><a class="bibr" href="#niceng247er6.s1.ref39" rid="niceng247er6.s1.ref39">Yee 2013</a></p>
|
|
<p>Retrospective cohort study</p>
|
|
<p>USA</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>N=26205 women</p>
|
|
<p>Mean (SD) age (years): NR (NR)</p>
|
|
<p>Maternal pre-pregnancy BMI: NR</p>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Gestational weight change:
|
|
<ul><li class="half_rhythm"><div>weight loss.</div></li></ul></p>
|
|
<p>Referent: no weight loss.</p>
|
|
<p><b>Gestational weight change definition:</b></p>
|
|
<p>Difference between weight at last visit and at 1<sup>st</sup> visit.</p></td><td headers="hd_h_niceng247er6.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>maternal age</div></li><li class="half_rhythm"><div>race/ethnicity</div></li><li class="half_rhythm"><div>parity</div></li><li class="half_rhythm"><div>education</div></li><li class="half_rhythm"><div>primary language.</div></li></ul>
|
|
</td><td headers="hd_h_niceng247er6.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>caesarean birth.</div></li></ul></td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">BMI: body mass index; CD: caesarean delivery; GD: gestational diabetes; GDM: gestational diabetes mellitus; GWL: gestational weight loss; EGWG: excessive gestational weight gain; ET: embryo transfer; ICSI: intracytoplasmic sperm injection; IPD: individual patient data; LGA: large for gestational; NEGWG: non-excessive gestational weight gain; NR: not reported; PE: pre-eclampsia; SD: standard deviation; SGA: small for gestational age; WIC: women, infants, and children.</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6tab3"><div id="niceng247er6.tab3" class="table"><h3><span class="title">Association between weight loss, inadequate gestational weight gain, excessive gestational weight gain (IOM gestational weight change categories) and maternal/neonatal/fetal outcomes in singleton and twin pregnancy: all BMI categories, parity and age strata</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.tab3_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.tab3_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_niceng247er6.tab3_1_1_1_1" style="text-align:center;vertical-align:middle;">Populations\Outcomes</th><th id="hd_h_niceng247er6.tab3_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_niceng247er6.tab3_1_1_1_2" style="text-align:center;vertical-align:middle;">Caesarean birth</th><th id="hd_h_niceng247er6.tab3_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_niceng247er6.tab3_1_1_1_3" style="text-align:center;vertical-align:middle;">Gestational diabetes</th><th id="hd_h_niceng247er6.tab3_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng247er6.tab3_1_1_1_4" style="text-align:center;vertical-align:middle;">Gestational hypertension</th><th id="hd_h_niceng247er6.tab3_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_niceng247er6.tab3_1_1_1_5" style="text-align:center;vertical-align:middle;">Pre-eclampsia</th><th id="hd_h_niceng247er6.tab3_1_1_1_6" rowspan="2" colspan="1" headers="hd_h_niceng247er6.tab3_1_1_1_6" style="text-align:center;vertical-align:middle;">Small for gestational age</th><th id="hd_h_niceng247er6.tab3_1_1_1_7" rowspan="2" colspan="1" headers="hd_h_niceng247er6.tab3_1_1_1_7" style="text-align:center;vertical-align:middle;">Large for gestational age</th><th id="hd_h_niceng247er6.tab3_1_1_1_8" colspan="4" rowspan="1" style="text-align:center;vertical-align:middle;">Childhood overweight</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_8" id="hd_h_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">3 years of age<sup>*</sup></th><th headers="hd_h_niceng247er6.tab3_1_1_1_8" id="hd_h_niceng247er6.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">2 to 5 years</th><th headers="hd_h_niceng247er6.tab3_1_1_1_8" id="hd_h_niceng247er6.tab3_1_1_2_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">5 to 10 years</th><th headers="hd_h_niceng247er6.tab3_1_1_1_8" id="hd_h_niceng247er6.tab3_1_1_2_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">10 to 18 years</th></tr></thead><tbody><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_1_1" colspan="11" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: Weight loss</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_2_1" colspan="11" rowspan="1" style="text-align:left;vertical-align:middle;">Singleton births</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged <15 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
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<p>No association</p>
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<p>(Very low quality)</p>
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</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_3_1 hd_b_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 15-17 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
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<p>Low risk</p>
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<p>(Moderate quality)</p>
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</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 18-19 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
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<p>Low risk</p>
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<p>(Moderate quality)</p>
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</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 20-34 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
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<p>High risk</p>
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<p>(Low quality)</p>
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|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
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<p>Low risk</p>
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<p>(Moderate quality)</p>
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</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
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<p>Low risk</p>
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<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low/high risk</p>
|
|
<p>Low to very low quality</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_15_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_16_1" colspan="11" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: Inadequate gestational weight gain</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_15_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_17_1" colspan="11" rowspan="1" style="text-align:left;vertical-align:middle;">Singleton pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged <15 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_18_1 hd_b_niceng247er6.tab3_1_1_16_1 hd_b_niceng247er6.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 15-17 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 18-19 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 20-34 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk/no association</p>
|
|
<p>(Moderate to low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>High quality</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk/no association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_22_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal weight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk/high risk/no association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_24_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight/obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_26_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_28_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_30_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_32_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk/high risk/no association</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_34_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_36_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_36_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_37_1" colspan="11" rowspan="1" style="text-align:left;vertical-align:middle;">Twin pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_38_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>((High quality))</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>((High quality))</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_38_1 hd_b_niceng247er6.tab3_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal weight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_40_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_41_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_42_1" colspan="11" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: Excessive gestational weight gain</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_41_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_43_1" colspan="11" rowspan="1" style="text-align:left;vertical-align:middle;">Singleton pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_44_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged <15 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_44_1 hd_b_niceng247er6.tab3_1_1_42_1 hd_b_niceng247er6.tab3_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 15-17 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 18-19 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_46_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Aged 20-34 years (referent: adequate GWG in 20-34 year olds)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate to low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk/high risk/no association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk/no association</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk/no association</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_48_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk/no association</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_50_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_51_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal weight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk/no association</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk/no association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_52_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI normal weight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_53_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI normal weight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_54_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk/no association</p>
|
|
<p>(Low to very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_55_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_56_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_57_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight/obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_58_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Very low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_59_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_60_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_61_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_62_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_63_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese I (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_64_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_65_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_66_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese II (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_67_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_68_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Nulliparous, pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_69_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Parous, pre-pregnancy BMI obese III (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_70_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1 hd_b_niceng247er6.tab3_1_1_70_1 hd_h_niceng247er6.tab3_1_1_1_2 hd_h_niceng247er6.tab3_1_1_1_3 hd_h_niceng247er6.tab3_1_1_1_4 hd_h_niceng247er6.tab3_1_1_1_5 hd_h_niceng247er6.tab3_1_1_1_6 hd_h_niceng247er6.tab3_1_1_1_7 hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_h_niceng247er6.tab3_1_1_2_2 hd_h_niceng247er6.tab3_1_1_2_3 hd_h_niceng247er6.tab3_1_1_2_4" id="hd_b_niceng247er6.tab3_1_1_71_1" colspan="11" rowspan="1" style="text-align:left;vertical-align:middle;">Twin pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_72_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_72_1 hd_b_niceng247er6.tab3_1_1_71_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_73_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight/normal weight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_74_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal weight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_75_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_76_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab3_1_1_1_1" id="hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab3_1_1_1_2 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_3 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_4 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_5 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_6 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab3_1_1_1_7 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_1 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_2 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_3 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab3_1_1_1_8 hd_h_niceng247er6.tab3_1_1_2_4 hd_b_niceng247er6.tab3_1_1_77_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>*</dt><dd><div id="niceng247er6.tab3_1"><p class="no_margin">referent for the outcome childhood overweight is adequate GWG in pre-pregnancy</p></div></dd></dl><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">BMI normal BMI: body mass index; GWG: gestational weight gain; IOM: Institute of Medicine; NR: not reported</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6tab4"><div id="niceng247er6.tab4" class="table"><h3><span class="title">Association between low, medium, high gestational weight change (study defined category) and maternal/neonatal/fetal outcomes in singleton pregnancy: all BMI categories strata</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.tab4_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Population\Outcomes</th><th id="hd_h_niceng247er6.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational diabetes</th><th id="hd_h_niceng247er6.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational hypertension</th><th id="hd_h_niceng247er6.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-eclampsia</th><th id="hd_h_niceng247er6.tab4_1_1_1_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Small for gestational age</th><th id="hd_h_niceng247er6.tab4_1_1_1_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Large for gestational age</th></tr></thead><tbody><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1 hd_h_niceng247er6.tab4_1_1_1_2 hd_h_niceng247er6.tab4_1_1_1_3 hd_h_niceng247er6.tab4_1_1_1_4 hd_h_niceng247er6.tab4_1_1_1_5 hd_h_niceng247er6.tab4_1_1_1_6" id="hd_b_niceng247er6.tab4_1_1_1_1" colspan="6" rowspan="1" style="text-align:left;vertical-align:middle;">Singleton pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_1_1 hd_h_niceng247er6.tab4_1_1_1_2 hd_h_niceng247er6.tab4_1_1_1_3 hd_h_niceng247er6.tab4_1_1_1_4 hd_h_niceng247er6.tab4_1_1_1_5 hd_h_niceng247er6.tab4_1_1_1_6" id="hd_b_niceng247er6.tab4_1_1_2_1" colspan="6" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: Low gestational weight gain</th></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_3_1 hd_b_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_3_1 hd_b_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_3_1 hd_b_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_3_1 hd_b_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_3_1 hd_b_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal weight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_6_1 hd_h_niceng247er6.tab4_1_1_1_2 hd_h_niceng247er6.tab4_1_1_1_3 hd_h_niceng247er6.tab4_1_1_1_4 hd_h_niceng247er6.tab4_1_1_1_5 hd_h_niceng247er6.tab4_1_1_1_6" id="hd_b_niceng247er6.tab4_1_1_7_1" colspan="6" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: Medium gestational weight gain</th></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_8_1 hd_b_niceng247er6.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_8_1 hd_b_niceng247er6.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_8_1 hd_b_niceng247er6.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_8_1 hd_b_niceng247er6.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_8_1 hd_b_niceng247er6.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1 hd_b_niceng247er6.tab4_1_1_10_1 hd_h_niceng247er6.tab4_1_1_1_2 hd_h_niceng247er6.tab4_1_1_1_3 hd_h_niceng247er6.tab4_1_1_1_4 hd_h_niceng247er6.tab4_1_1_1_5 hd_h_niceng247er6.tab4_1_1_1_6" id="hd_b_niceng247er6.tab4_1_1_11_1" colspan="6" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: High gestational weight gain</th></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_12_1 hd_b_niceng247er6.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_12_1 hd_b_niceng247er6.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_12_1 hd_b_niceng247er6.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_12_1 hd_b_niceng247er6.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_12_1 hd_b_niceng247er6.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal weight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr><tr><th headers="hd_h_niceng247er6.tab4_1_1_1_1" id="hd_b_niceng247er6.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: medium weight gain in pre-pregnancy BMI normal)</th><td headers="hd_h_niceng247er6.tab4_1_1_1_2 hd_b_niceng247er6.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_3 hd_b_niceng247er6.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_4 hd_b_niceng247er6.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_5 hd_b_niceng247er6.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab4_1_1_1_6 hd_b_niceng247er6.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">BMI: body mass index</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6tab5"><div id="niceng247er6.tab5" class="table"><h3><span class="title">Association between low (<8 kg) gestational weight gain and high (>16 kg) gestational weight gain (Independent Swedish gestational weight change categories) and maternal/neonatal/fetal outcomes in singleton pregnancy: all BMI categories strata</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.tab5/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.tab5_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Population\Outcomes</th><th id="hd_h_niceng247er6.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Caesarean birth</th><th id="hd_h_niceng247er6.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational diabetes</th><th id="hd_h_niceng247er6.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational hypertension</th><th id="hd_h_niceng247er6.tab5_1_1_1_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-eclampsia</th><th id="hd_h_niceng247er6.tab5_1_1_1_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Small for gestational age</th><th id="hd_h_niceng247er6.tab5_1_1_1_7" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Large for gestational age</th></tr></thead><tbody><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1 hd_h_niceng247er6.tab5_1_1_1_2 hd_h_niceng247er6.tab5_1_1_1_3 hd_h_niceng247er6.tab5_1_1_1_4 hd_h_niceng247er6.tab5_1_1_1_5 hd_h_niceng247er6.tab5_1_1_1_6 hd_h_niceng247er6.tab5_1_1_1_7" id="hd_b_niceng247er6.tab5_1_1_1_1" colspan="7" rowspan="1" style="text-align:left;vertical-align:middle;">Singleton pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_1_1 hd_h_niceng247er6.tab5_1_1_1_2 hd_h_niceng247er6.tab5_1_1_1_3 hd_h_niceng247er6.tab5_1_1_1_4 hd_h_niceng247er6.tab5_1_1_1_5 hd_h_niceng247er6.tab5_1_1_1_6 hd_h_niceng247er6.tab5_1_1_1_7" id="hd_b_niceng247er6.tab5_1_1_2_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: Low (<8 kg) gestational weight gain</th></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI <20 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_3_1 hd_b_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_3_1 hd_b_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_3_1 hd_b_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_3_1 hd_b_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_3_1 hd_b_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_3_1 hd_b_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI 20-24.9 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI 25-29.9 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI 30-34.9 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI ≥35 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1 hd_b_niceng247er6.tab5_1_1_7_1 hd_h_niceng247er6.tab5_1_1_1_2 hd_h_niceng247er6.tab5_1_1_1_3 hd_h_niceng247er6.tab5_1_1_1_4 hd_h_niceng247er6.tab5_1_1_1_5 hd_h_niceng247er6.tab5_1_1_1_6 hd_h_niceng247er6.tab5_1_1_1_7" id="hd_b_niceng247er6.tab5_1_1_8_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: (>16 kg) gestational weight gain</th></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI <20 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_9_1 hd_b_niceng247er6.tab5_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_9_1 hd_b_niceng247er6.tab5_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_9_1 hd_b_niceng247er6.tab5_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_9_1 hd_b_niceng247er6.tab5_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_9_1 hd_b_niceng247er6.tab5_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_9_1 hd_b_niceng247er6.tab5_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI 20-24.9 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI 25-29.9 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI 30-34.9 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab5_1_1_1_1" id="hd_b_niceng247er6.tab5_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI ≥35 (referent: 8 to 16 kg)</th><td headers="hd_h_niceng247er6.tab5_1_1_1_2 hd_b_niceng247er6.tab5_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab5_1_1_1_3 hd_b_niceng247er6.tab5_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_4 hd_b_niceng247er6.tab5_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_5 hd_b_niceng247er6.tab5_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_6 hd_b_niceng247er6.tab5_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab5_1_1_1_7 hd_b_niceng247er6.tab5_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">BMI: body mass index; GWG: gestational weight gain; IOM: Institute of Medicine; NR: not reported</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6tab6"><div id="niceng247er6.tab6" class="table"><h3><span class="title">Association between gestational weight change of <0.5 to 6.9 kg, 6.7 to 10 kg, 13.7 to 29 kg and >24.6 to ≥29.1 kg (Swedish gestational weight change categories) and maternal/neonatal/fetal outcomes in singleton pregnancy: all BMI categories strata</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.tab6/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.tab6_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Population\Outcomes</th><th id="hd_h_niceng247er6.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Caesarean birth</th><th id="hd_h_niceng247er6.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational diabetes</th><th id="hd_h_niceng247er6.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational hypertension</th><th id="hd_h_niceng247er6.tab6_1_1_1_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-eclampsia</th><th id="hd_h_niceng247er6.tab6_1_1_1_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Small for gestational age</th><th id="hd_h_niceng247er6.tab6_1_1_1_7" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Large for gestational age</th></tr></thead><tbody><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1 hd_h_niceng247er6.tab6_1_1_1_2 hd_h_niceng247er6.tab6_1_1_1_3 hd_h_niceng247er6.tab6_1_1_1_4 hd_h_niceng247er6.tab6_1_1_1_5 hd_h_niceng247er6.tab6_1_1_1_6 hd_h_niceng247er6.tab6_1_1_1_7" id="hd_b_niceng247er6.tab6_1_1_1_1" colspan="7" rowspan="1" style="text-align:left;vertical-align:middle;">Singleton pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_1_1 hd_h_niceng247er6.tab6_1_1_1_2 hd_h_niceng247er6.tab6_1_1_1_3 hd_h_niceng247er6.tab6_1_1_1_4 hd_h_niceng247er6.tab6_1_1_1_5 hd_h_niceng247er6.tab6_1_1_1_6 hd_h_niceng247er6.tab6_1_1_1_7" id="hd_b_niceng247er6.tab6_1_1_2_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: <0.5 to 6.9 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_3_1 hd_b_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_3_1 hd_b_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_3_1 hd_b_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_3_1 hd_b_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_3_1 hd_b_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_3_1 hd_b_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_6_1 hd_h_niceng247er6.tab6_1_1_1_2 hd_h_niceng247er6.tab6_1_1_1_3 hd_h_niceng247er6.tab6_1_1_1_4 hd_h_niceng247er6.tab6_1_1_1_5 hd_h_niceng247er6.tab6_1_1_1_6 hd_h_niceng247er6.tab6_1_1_1_7" id="hd_b_niceng247er6.tab6_1_1_7_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: 6.7 to 10 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_8_1 hd_b_niceng247er6.tab6_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_8_1 hd_b_niceng247er6.tab6_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_8_1 hd_b_niceng247er6.tab6_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_8_1 hd_b_niceng247er6.tab6_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_8_1 hd_b_niceng247er6.tab6_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_8_1 hd_b_niceng247er6.tab6_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_10_1 hd_h_niceng247er6.tab6_1_1_1_2 hd_h_niceng247er6.tab6_1_1_1_3 hd_h_niceng247er6.tab6_1_1_1_4 hd_h_niceng247er6.tab6_1_1_1_5 hd_h_niceng247er6.tab6_1_1_1_6 hd_h_niceng247er6.tab6_1_1_1_7" id="hd_b_niceng247er6.tab6_1_1_11_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: 13.7 to 29 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_12_1 hd_b_niceng247er6.tab6_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_12_1 hd_b_niceng247er6.tab6_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_12_1 hd_b_niceng247er6.tab6_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_12_1 hd_b_niceng247er6.tab6_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Low quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_12_1 hd_b_niceng247er6.tab6_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_12_1 hd_b_niceng247er6.tab6_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1 hd_b_niceng247er6.tab6_1_1_15_1 hd_h_niceng247er6.tab6_1_1_1_2 hd_h_niceng247er6.tab6_1_1_1_3 hd_h_niceng247er6.tab6_1_1_1_4 hd_h_niceng247er6.tab6_1_1_1_5 hd_h_niceng247er6.tab6_1_1_1_6 hd_h_niceng247er6.tab6_1_1_1_7" id="hd_b_niceng247er6.tab6_1_1_16_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: >24.6 to ≥29.1 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI underweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_17_1 hd_b_niceng247er6.tab6_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_17_1 hd_b_niceng247er6.tab6_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_17_1 hd_b_niceng247er6.tab6_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_17_1 hd_b_niceng247er6.tab6_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_17_1 hd_b_niceng247er6.tab6_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_17_1 hd_b_niceng247er6.tab6_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI normal (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI overweight (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab6_1_1_1_1" id="hd_b_niceng247er6.tab6_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-pregnancy BMI obese (referent: adequate GWG)</th><td headers="hd_h_niceng247er6.tab6_1_1_1_2 hd_b_niceng247er6.tab6_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_3 hd_b_niceng247er6.tab6_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_4 hd_b_niceng247er6.tab6_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_5 hd_b_niceng247er6.tab6_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab6_1_1_1_6 hd_b_niceng247er6.tab6_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab6_1_1_1_7 hd_b_niceng247er6.tab6_1_1_20_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">BMI: body mass index; GWG: gestational weight gain; NR: not reported</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6tab7"><div id="niceng247er6.tab7" class="table"><h3><span class="title">Association between Weight change (thresholds as reported in the studies) and maternal/neonatal/fetal outcomes in singleton pregnancy</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.tab7/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.tab7_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Population\Outcomes</th><th id="hd_h_niceng247er6.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Caesarean birth</th><th id="hd_h_niceng247er6.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational diabetes</th><th id="hd_h_niceng247er6.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Gestational hypertension</th><th id="hd_h_niceng247er6.tab7_1_1_1_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Pre-eclampsia</th><th id="hd_h_niceng247er6.tab7_1_1_1_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Small for gestational age</th><th id="hd_h_niceng247er6.tab7_1_1_1_7" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Large for gestational age</th></tr></thead><tbody><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: >20 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_1_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_2_1" colspan="7" rowspan="1" style="text-align:left;vertical-align:middle;">Singleton pregnancy</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: ≤20 kg)</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_3_1 hd_b_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_3_1 hd_b_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_3_1 hd_b_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_3_1 hd_b_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_3_1 hd_b_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_3_1 hd_b_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_3_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_4_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: <8 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: 8 to 15.9 kg)</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_5_1 hd_b_niceng247er6.tab7_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_5_1 hd_b_niceng247er6.tab7_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_5_1 hd_b_niceng247er6.tab7_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_5_1 hd_b_niceng247er6.tab7_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_5_1 hd_b_niceng247er6.tab7_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_5_1 hd_b_niceng247er6.tab7_1_1_4_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_5_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_6_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: ≥16 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: 8 to 15.9 kg)</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_7_1 hd_b_niceng247er6.tab7_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_7_1 hd_b_niceng247er6.tab7_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_7_1 hd_b_niceng247er6.tab7_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_7_1 hd_b_niceng247er6.tab7_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_7_1 hd_b_niceng247er6.tab7_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_7_1 hd_b_niceng247er6.tab7_1_1_6_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_7_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_8_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: <10 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>All pre-pregnancy BMI categories (referent: 10 to 15 kg)</p>
|
|
<p>CB before labour</p>
|
|
</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_9_1 hd_b_niceng247er6.tab7_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_9_1 hd_b_niceng247er6.tab7_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_9_1 hd_b_niceng247er6.tab7_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_9_1 hd_b_niceng247er6.tab7_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_9_1 hd_b_niceng247er6.tab7_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_9_1 hd_b_niceng247er6.tab7_1_1_8_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>All pre-pregnancy BMI categories (referent: 10 to 15 kg)</p>
|
|
<p>CB during labour</p>
|
|
</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_10_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_10_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_11_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: 16 to 19 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_12_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>All pre-pregnancy BMI categories (referent: 10 to 15 kg)</p>
|
|
<p>CB before labour</p>
|
|
</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_12_1 hd_b_niceng247er6.tab7_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>No association</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_12_1 hd_b_niceng247er6.tab7_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_12_1 hd_b_niceng247er6.tab7_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_12_1 hd_b_niceng247er6.tab7_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_12_1 hd_b_niceng247er6.tab7_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_12_1 hd_b_niceng247er6.tab7_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>All pre-pregnancy BMI categories (referent: 10 to 15 kg)</p>
|
|
<p>CB during labour</p>
|
|
</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_13_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_14_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: ≥20 kg gestational weight change</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>All pre-pregnancy BMI categories (referent: 10 to 15 kg)</p>
|
|
<p>CB before labour</p>
|
|
</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_15_1 hd_b_niceng247er6.tab7_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_15_1 hd_b_niceng247er6.tab7_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_15_1 hd_b_niceng247er6.tab7_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_15_1 hd_b_niceng247er6.tab7_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_15_1 hd_b_niceng247er6.tab7_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_15_1 hd_b_niceng247er6.tab7_1_1_14_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>All pre-pregnancy BMI categories (referent: 10 to 15 kg)</p>
|
|
<p>CB during labour</p>
|
|
</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>High risk</p>
|
|
<p>(High quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_16_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1 hd_b_niceng247er6.tab7_1_1_16_1 hd_h_niceng247er6.tab7_1_1_1_2 hd_h_niceng247er6.tab7_1_1_1_3 hd_h_niceng247er6.tab7_1_1_1_4 hd_h_niceng247er6.tab7_1_1_1_5 hd_h_niceng247er6.tab7_1_1_1_6 hd_h_niceng247er6.tab7_1_1_1_7" id="hd_b_niceng247er6.tab7_1_1_17_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Risk factor: weight loss</th></tr><tr><th headers="hd_h_niceng247er6.tab7_1_1_1_1" id="hd_b_niceng247er6.tab7_1_1_18_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">All pre-pregnancy BMI categories (referent: no weight loss) CB before labour</th><td headers="hd_h_niceng247er6.tab7_1_1_1_2 hd_b_niceng247er6.tab7_1_1_18_1 hd_b_niceng247er6.tab7_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">
|
|
<p>Low risk</p>
|
|
<p>(Moderate quality)</p>
|
|
</td><td headers="hd_h_niceng247er6.tab7_1_1_1_3 hd_b_niceng247er6.tab7_1_1_18_1 hd_b_niceng247er6.tab7_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_4 hd_b_niceng247er6.tab7_1_1_18_1 hd_b_niceng247er6.tab7_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_5 hd_b_niceng247er6.tab7_1_1_18_1 hd_b_niceng247er6.tab7_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_6 hd_b_niceng247er6.tab7_1_1_18_1 hd_b_niceng247er6.tab7_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td><td headers="hd_h_niceng247er6.tab7_1_1_1_7 hd_b_niceng247er6.tab7_1_1_18_1 hd_b_niceng247er6.tab7_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">NR</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">BMI: body mass index; CB: caesarean birth; NR: not reported</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6appjtab1"><div id="niceng247er6.appj.tab1" class="table"><h3><span class="label">Table 56</span><span class="title">Excluded studies and reasons for their exclusion</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.appj.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.appj.tab1_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Study</th><th id="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Code [Reason]</th></tr></thead><tbody><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Abenhaim, H.A. and Benjamin, A. (2011) Higher Caesarean Section Rates in Women With Higher Body Mass Index: Are We Managing Labour Differently?. Journal of Obstetrics and Gynaecology Canada
|
|
33(5): 443–448
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/21639963" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21639963</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p><i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Abenhaim, H.A., Kinch, R.A., Morin, L.
|
|
et al. (2007) Effect of pre-pregnancy body mass index categories on obstetrical and neonatal outcomes. Archives of Gynecology and Obstetrics
|
|
275(1): 39–43
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/16967276" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16967276</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Abrams, B.F., Leonard, S.A., Kan, P.
|
|
et al. (2022) Interpregnancy weight change: associations with severe maternal morbidity and neonatal outcomes. American Journal of Obstetrics and Gynecology MFM
|
|
4(3): 100596
|
|
[<a href="/pmc/articles/PMC10960247/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC10960247</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/35181513" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35181513</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI change between 2 consecutive pregnancies with outcomes in the second pregnancy. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Adane, A.A.; Tooth, L.R.; Mishra, G.D. (2017) Pre-pregnancy weight change and incidence of gestational diabetes mellitus: A finding from a prospective cohort study. Diabetes Research and Clinical Practice
|
|
124: 72–80
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/28110238" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28110238</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Al-Hassany, L., Wahab, R.J., Steegers, E.A.P.
|
|
et al. (2020) Smoking cessation in early-pregnancy, gestational weight gain and subsequent risks of pregnancy complications. European Journal of Obstetrics and Gynecology and Reproductive Biology
|
|
253: 7–14
|
|
[<a href="/pmc/articles/PMC7613755/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7613755</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32745817" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32745817</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is smoking cessation in early pregnancy. The study includes an analysis by gestational weight gain and risks of maternal pregnancy complications, however the comparison group is those who continued smoking during pregnancy with no reference to gestational weight gain, therefore this is not a relevant comparison</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Alberico, S., Montico, M., Barresi, V.
|
|
et al. (2014) The role of gestational diabetes, pre - pregnancy body mass index and gestational weight gain on the risk of newborn macrosomia: Results from a prospective multicentre study. BMC Pregnancy and Childbirth
|
|
14(1): 23
|
|
[<a href="/pmc/articles/PMC3898774/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3898774</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24428895" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24428895</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Albers, Lucia, Sobotzki, Christina, Kus, Oliver
|
|
et al. (2018) Maternal smoking during pregnancy and offspring overweight: is there a dose-response relationship? An individual patient data meta-analysis. International journal of obesity (2005)
|
|
42(7): 1249–1264
|
|
[<a href="/pmc/articles/PMC6685293/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6685293</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/29717267" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29717267</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is maternal smoking during pregnancy. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Amark, H.; Westgren, M.; Persson, M. (2019) Prediction of large-for-gestational-age infants in pregnancies complicated by obesity: A population-based cohort study. Acta Obstetricia et Gynecologica Scandinavica
|
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98(6): 769–776
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/30687927" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30687927</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Andersen, Camilla Schou, Gamborg, Michael, Sorensen, Thorkild I A
|
|
et al. (2011) Weight gain in different periods of pregnancy and offspring’s body mass index at 7 years of age. International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity
|
|
6(22): e179–86
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/20883124" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20883124</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Article unavailable</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Antonakou, A.; Papoutsis, D.; Kechagia, A. (2017) Does gestational weight gain of more than 12 kg in women increase the risk of a cesarean section delivery, gestational diabetes and pregnancy induced hypertension? A retrospective case series. Clinical and Experimental Obstetrics and Gynecology
|
|
44(4): 540–544
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not adjust for covariates in the analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ardic, Cuneyt, Colak, Sabri, Uzun, Kerem
|
|
et al. (2020) Maternal Gestational Diabetes and Early Childhood Obesity: A Retrospective Cohort Study. Childhood obesity (Print)
|
|
16(8): 579–585
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/33146559" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33146559</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is gestational diabetes. No gestational weight change by reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ashtree, Deborah N, Osborne, Deborah A, Lee, Amelia
|
|
et al. (2022) Gestational weight gain is associated with childhood height, weight and BMI in the Peri/Postnatal Epigenetic Twins Study. Journal of developmental origins of health and disease: 1–9 [<a href="https://pubmed.ncbi.nlm.nih.gov/35322788" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35322788</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Analysis not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study assessed the association between gestational weight gain and childhood anthropometric parameters. However the absolute values for gestational weight were not reported, these were incorporated in the analyses as z-scores, therefore the reported results are not relevant for this review question</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Badon, Sylvia E, Dublin, Sascha, Nance, Nerissa
|
|
et al. (2021) Gestational weight gain and adverse pregnancy outcomes by pre-pregnancy BMI category in women with chronic hypertension: A cohort study. Pregnancy hypertension
|
|
23: 27–33
|
|
[<a href="/pmc/articles/PMC7904620/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7904620</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/33181475" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33181475</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Analysis not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study assessed the association between gestational weight gain and adverse birth outcomes. However the absolute values for gestational weight were not reported, these were incorporated in the analyses as zscores, therefore the reported results are not rel evant for this review question</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bakketeig, L.S., Jacobsen, G., Hoffman, H.J.
|
|
et al. (1993) Pre-pregnancy risk factors of small-for-gestational age births among parous women in Scandinavia. Acta Obstetricia et Gynecologica Scandinavica
|
|
72(4): 273–279
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/8389514" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8389514</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bar-Zeev, Y.; Haile, Z.T.; Chertok, I.A. (2020) Association between Prenatal Smoking and Gestational Diabetes Mellitus. Obstetrics and Gynecology
|
|
135(1): 91–99
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/31809434" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31809434</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is prenatal smoking. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Barau, G., Robillard, P.-Y., Hulsey, T.C.
|
|
et al. (2006) Linear association between maternal pre-pregnancy body mass index and risk of caesarean section in term deliveries. BJOG: An International Journal of Obstetrics and Gynaecology
|
|
113(10): 1173–1177
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/16972860" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16972860</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p><i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Barnes, R A, Edghill, N, Mackenzie, J
|
|
et al. (2013) Predictors of large and small for gestational age birthweight in offspring of women with gestational diabetes mellitus. Diabetic medicine : a journal of the British Diabetic Association
|
|
30(9): 1040–6
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/23551273" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23551273</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p><i>Retrospective audit of clinical data</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Barquiel, B., Herranz, L., Grande, C.
|
|
et al. (2014) Body weight, weight gain and hyperglycaemia are associated with hypertensive disorders of pregnancy in women with gestational diabetes. Diabetes and Metabolism
|
|
40(3): 204–210
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/24503192" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24503192</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Analysis not relevant to this protocol</p>
|
|
<p><i>Multivariate analysis conducted, which did not report association effect estimates</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Barquiel, Beatriz, Herranz, Lucrecia, Meneses, Diego
|
|
et al. (2018) Optimal Gestational Weight Gain for Women with Gestational Diabetes and Morbid Obesity. Maternal and child health journal
|
|
22(9): 1297–1305
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/29497985" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29497985</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study did not adjust for covariates in the analysis</p>
|
|
<p>
|
|
<i>Univariate regression and correlation analysis were reported. Adjusted estimates were reported as sensitivity and specificity, which are not relevant outcomes measures for this review</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Basraon, S.K., Mele, L., Myatt, L.
|
|
et al. (2015) Relationship of Early Pregnancy Waist-to-Hip Ratio versus Body Mass Index with Gestational Diabetes Mellitus and Insulin Resistance. American Journal of Perinatology
|
|
33(1): 114–122
|
|
[<a href="/pmc/articles/PMC5283057/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5283057</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26352680" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26352680</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is BMI and waist to hip ratio in early pregnancy. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ben-Haroush, Avi, Hadar, Eran, Chen, Rony
|
|
et al. (2009) Maternal obesity is a major risk factor for large-for-gestational-infants in pregnancies complicated by gestational diabetes. Archives of gynecology and obstetrics
|
|
279(4): 539–43
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/18758799" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18758799</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is maternal obesity. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Berggren, E.K.; Stuebe, A.M.; Boggess, K.A. (2014) Excess Maternal Weight Gain and Large for Gestational Age Risk among Women with Gestational Diabetes. American Journal of Perinatology [<a href="/pmc/articles/PMC4701209/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4701209</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24971567" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24971567</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bergholt, T., Lim, L.K., Jorgensen, J.S.
|
|
et al. (2007) Maternal body mass index in the first trimester and risk of cesarean delivery in nulliparous women in spontaneous labor. American Journal of Obstetrics and Gynecology
|
|
196(2): e1–163 [<a href="https://pubmed.ncbi.nlm.nih.gov/17306665" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17306665</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p><i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Berntorp, Kerstin, Anderberg, Eva, Claesson, Rickard
|
|
et al. (2015) The relative importance of maternal body mass index and glucose levels for prediction of large-for-gestational-age births. BMC pregnancy and childbirth
|
|
15: 280
|
|
[<a href="/pmc/articles/PMC4627395/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4627395</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26514116" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26514116</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is maternal age, BMI, 2-h glucose, smoker and parity. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Black, MH, Sacks, DA, Xiang, AH
|
|
et al. (2013) The relative contribution of pre-pregnancy overweight and obesity, gestational weight gain, and IADPSG-defined gestational diabetes mellitus to fetal overgrowth. Diabetes care
|
|
36(1): 56–62
|
|
[<a href="/pmc/articles/PMC3526206/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3526206</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/22891256" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22891256</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bodnar
|
|
LM, Pugh
|
|
SJ, Abrams
|
|
B, Himes
|
|
KP HJ (2014) Gestational weight gain in twin pregnancies and maternal and child health: a systematic review. Journal of Perinatology
|
|
4(34): 252–63 [<a href="/pmc/articles/PMC4046859/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4046859</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24457254" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24457254</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Superseded by more recent publication</p>
|
|
<p><i>More recent SR included all the same studies</i> - <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a></p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bodnar, L.M., Catov, J.M., Klebanoff, M.A.
|
|
et al. (2007) Pre-Pregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy. Epidemiology
|
|
18(2): 234–239
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17237733" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17237733</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bodnar, L.M., Himes, K.P., Abrams, B.
|
|
et al. (2019) Gestational Weight Gain and Adverse Birth Outcomes in Twin Pregnancies. Obstetrics and Gynecology
|
|
134(5): 1075–1086
|
|
[<a href="/pmc/articles/PMC6814560/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6814560</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/31599828" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31599828</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study from a systematic review that is included</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bodnar, L.M., Himes, K.P., Abrams, B.
|
|
et al. (2018) Early-pregnancy weight gain and the risk of preeclampsia: A case-cohort study. Pregnancy Hypertension
|
|
14: 205–212
|
|
[<a href="/pmc/articles/PMC7879463/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7879463</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30527113" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30527113</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bodnar, L.M., Ness, R.B., Markovic, N.
|
|
et al. (2005) The risk of preeclampsia rises with increasing pre-pregnancy body mass index. Annals of Epidemiology
|
|
15(7): 475–482
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/16029839" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16029839</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Boghossian, N.S., Frongillo, E.A., Cai, B.
|
|
et al. (2019) Associations of maternal gestational weight gain with the risk of offspring obesity and body mass index Z scores beyond the mean. Annals of Epidemiology
|
|
32: 64–71e2
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/30799201" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30799201</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Borghesi, Y., Labreuche, J., Duhamel, A.
|
|
et al. (2017) Risk of cesarean delivery among pregnant women with class III obesity. International Journal of Gynecology and Obstetrics
|
|
136(2): 168–174
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/28099722" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28099722</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Bottalico, JN (2007) Recurrent Gestational Diabetes: risk Factors, Diagnosis, Management, and Implications. Seminars in perinatology
|
|
31(3): 176–184
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17531899" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17531899</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p>
|
|
<i>Narrative review</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Brawarsky, P., Stotland, N.E., Jackson, R.A.
|
|
et al. (2005) Pre-pregnancy and pregnancy-related factors and the risk of excessive or inadequate gestational weight gain. International Journal of Gynecology and Obstetrics
|
|
91(2): 125–131
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/16202415" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16202415</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not adjust for covariates in the analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Catov, J.M., Sun, B., Lewis, C.E.
|
|
et al. (2022) Pre-Pregnancy weight change associated with high gestational weight gain. Obesity
|
|
30(2): 524–534
|
|
[<a href="/pmc/articles/PMC9996907/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC9996907</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/35080338" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35080338</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p><i>Study reported gestational weight gain as an outcome rather than the risk factor</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Catov, Janet M, Ness, Roberta B, Kip, Kevin E
|
|
et al. (2007) Risk of early or severe pre-eclampsia related to pre-existing conditions. International journal of epidemiology
|
|
36(2): 412–9
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17255351" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17255351</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI, amongst other risk factors. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ceulemans, D., De Mulder, P., Lebbe, B.
|
|
et al. (2021) Gestational weight gain and postpartum weight retention after bariatric surgery: data from a prospective cohort study. Surgery for Obesity and Related Diseases
|
|
17(4): 659–666
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/33549505" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33549505</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not adjust for covariates in the analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Chasan-Taber, Lisa, Silveira, Marushka, Waring, Molly E
|
|
et al. (2016) Gestational Weight Gain, Body Mass Index, and Risk of Hypertensive Disorders of Pregnancy in a Predominantly Puerto Rican Population. Maternal and child health journal
|
|
20(9): 1804–13
|
|
[<a href="/pmc/articles/PMC5007203/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5007203</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/27003150" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27003150</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Chattrapiban, T., Smit, H.A., Wijga, A.H.
|
|
et al. (2020) The joint effect of maternal smoking during pregnancy and maternal pre-pregnancy overweight on infants’ term birth weight. BMC Pregnancy and Childbirth
|
|
20(1): 132
|
|
[<a href="/pmc/articles/PMC7047372/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7047372</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32106826" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32106826</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is maternal smoking status and pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Cheng, Christine J, Bommarito, Kerry, Noguchi, Akihiko
|
|
et al. (2004) Body mass index change between pregnancies and small for gestational age births. Obstetrics and gynecology
|
|
104(2): 286–92
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/15292001" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15292001</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p>
|
|
<i>Case-control study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Chu, S.Y., Callaghan, W.M., Kim, S.Y.
|
|
et al. (2007) Maternal obesity and risk of gestational diabetes mellitus. Diabetes Care
|
|
30(8): 2070–2076
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17416786" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17416786</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is BMI. No gestational weight change was reported by the systematic review</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Chu, S.Y., Kim, S.Y., Schmid, C.H.
|
|
et al. (2007) Maternal obesity and risk of cesarean delivery: A meta-analysis. Obesity Reviews
|
|
8(5): 385–394
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17716296" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17716296</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is BMI. No gestational weight change was reported by the systematic review</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Cooray, S.D., Boyle, J.A., Soldatos, G.
|
|
et al. (2019) Prognostic prediction models for pregnancy complications in women with gestational diabetes: A protocol for systematic review, critical appraisal and meta-analysis. Systematic Reviews
|
|
8(1): 270
|
|
[<a href="/pmc/articles/PMC6844063/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6844063</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/31711547" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31711547</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Review protocol</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Daly, Amy L, Sriram, Nina, Woodall, Cheryl
|
|
et al. (2018) Risk factors associated with hypertensive disorders of pregnancy within an urban indigenous population in south western Sydney. Internal medicine journal
|
|
48(3): 269–275
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/29083111" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29083111</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Danilack, Valery A; Brousseau, E Christine; Phipps, Maureen G (2018) The Effect of Gestational Weight Gain on Persistent Increase in Body Mass Index in Adolescents: A Longitudinal Study. Journal of women’s health (2002)
|
|
27(12): 1456–1458 [<a href="/pmc/articles/PMC6306665/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6306665</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/29608127" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29608127</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p>
|
|
<i>Outcome is persistent BMI increase</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Daundasekara, S.S., O’connor, D.P., Cardoso, J.B.
|
|
et al. (2020) Risk of excess and inadequate gestational weight gain among hispanic women: Effects of immigration generational status. International Journal of Environmental Research and Public Health
|
|
17(18): 1–13 [<a href="/pmc/articles/PMC7560227/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7560227</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32899746" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32899746</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study reported on pregnancy alcohol use, smoking during pregnancy</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Deierlein, A L, Siega-Riz, A M, Herring, A H
|
|
et al. (2012) Gestational weight gain and predicted changes in offspring anthropometrics between early infancy and 3 years. Pediatric obesity
|
|
7(2): 134–42
|
|
[<a href="/pmc/articles/PMC3313077/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3313077</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/22434753" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22434753</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study reported on weight-for-age, length-for-age, and weight-for-length z-scores</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Dempsey, J.C., Ashiny, Z., Qiu, C.-F.
|
|
et al. (2005) Maternal pre-pregnancy overweight status and obesity as risk factors for cesarean delivery. Journal of Maternal-Fetal and Neonatal Medicine
|
|
17(3): 179–185
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/16147820" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16147820</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Dietz, P.M., Callaghan, W.M., Smith, R.
|
|
et al. (2009) Low pregnancy weight gain and small for gestational age: a comparison of the association using 3 different measures of small for gestational age. American Journal of Obstetrics and Gynecology
|
|
201(1): e1–53 [<a href="https://pubmed.ncbi.nlm.nih.gov/19576374" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19576374</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Duckitt, K. and Harrington, D. (2005) Risk factors for pre-eclampsia at antenatal booking: Systematic review of controlled studies. British Medical Journal
|
|
330(7491): 565–567
|
|
[<a href="/pmc/articles/PMC554027/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC554027</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/15743856" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15743856</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI, amongst other risk factors. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Eraslan Sahin, M. and Col Madendag, I. (2019) Effect of Gestational Weight Gain on Perinatal Outcomes in Low Risk Pregnancies with Normal Pre-Pregnancy Body Mass Index. BioMed Research International
|
|
2019: 3768601
|
|
[<a href="/pmc/articles/PMC6636447/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6636447</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/31355258" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31355258</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in Turkey</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Faucher, MA and Barger, MK (2015) Gestational weight gain in obese women by class of obesity and select maternal/newborn outcomes: A systematic review. Women and birth : journal of the Australian College of Midwives
|
|
28(3): e70–9
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/25866207" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25866207</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Systematic review. Included studies checked for eligibility and included if relevant</p>
|
|
<p>
|
|
<i>Studies by Blomberg and Kominiarek included for the caesarean birth outcome</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Fortner, R.T., Pekow, P., Solomon, C.G.
|
|
et al. (2009) Pre-Pregnancy body mass index, gestational weight gain, and risk of hypertensive pregnancy among Latina women. American Journal of Obstetrics and Gynecology
|
|
200(2): e1–167 [<a href="https://pubmed.ncbi.nlm.nih.gov/19070831" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19070831</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a id="niceng247er6.appj.ref54"></a>Fox, N.S., Rebarber, A., Roman, A.S.
|
|
et al. (2010) Weight gain in twin pregnancies and adverse outcomes: Examining the 2009 institute of medicine guidelines. Obstetrics and Gynecology
|
|
116(1): 100–106
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/20567174" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20567174</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Studies from a systematic review that is included</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Fujiwara, Kana, Aoki, Shigeru, Kurasawa, Kentaro
|
|
et al. (2014) Associations of maternal pre-pregnancy underweight with small - for - gestational - age and spontaneous preterm birth, and optimal gestational weight gain in Japanese women. The journal of obstetrics and gynaecology research
|
|
40(4): 988–94
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/24428432" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24428432</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Gao, Ming, Cao, Shu, Li, Ninghua
|
|
et al. (2022) Risks of overweight in the offspring of women with gestational diabetes at different developmental stages: A meta-analysis with more than half a million offspring. Obesity reviews : an official journal of the International Association for the Study of Obesity
|
|
23(3): e13395
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/34820996" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 34820996</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Review protocol</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a id="niceng247er6.appj.ref57"></a>Gavard, J.A. and Artal, R. (2014) Gestational weight gain and maternal and neonatal outcomes in term twin pregnancies in obese women. Twin Research and Human Genetics
|
|
17(2): 127–133
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/24423582" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24423582</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Studies from a systematic review that is included</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Gavard, Jeffrey A and Artal, Raul (2014) The association of gestational weight gain with birth weight in obese pregnant women by obesity class and diabetic status: a population-based historical cohort study. Maternal and child health journal
|
|
18(4): 1038–47
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/24077985" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24077985</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Getahun, D., Ananth, C.V., Peltier, M.R.
|
|
et al. (2007) Changes in pre-pregnancy body mass index between the first and second pregnancies and risk of large-for-gestational-age birth. American Journal of Obstetrics and Gynecology
|
|
196(6): e1–530 [<a href="https://pubmed.ncbi.nlm.nih.gov/17547882" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17547882</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI between the first 2 pregnancies. No gestational weight change was reported</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Getahun, D., Fassett, M.J., Jacobsen, S.J.
|
|
et al. (2022) Perinatal outcomes after bariatric surgery. American Journal of Obstetrics and Gynecology
|
|
226(1): 121e1–121e16 [<a href="https://pubmed.ncbi.nlm.nih.gov/34216568" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 34216568</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Gibson, K.S.; Waters, T.P.; Catalano, P.M. (2012) Maternal weight gain in women who develop gestational diabetes mellitus. Obstetrics and Gynecology
|
|
119(3): 560–565
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/22353954" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22353954</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Goldstein, RF, Abell, SK, Ranasinha, S
|
|
et al. (2017) Association of Gestational Weight Gain With Maternal and Infant Outcomes: A Systematic Review and Meta - analysis. JAMA
|
|
317(21): 2207–2225
|
|
[<a href="/pmc/articles/PMC5815056/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5815056</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28586887" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28586887</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Systematic review. Included studies checked for eligibility and included if relevant</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Grandfils, S., Demondion, D., Kyheng, M.
|
|
et al. (2019) Impact of gestational weight gain on perinatal outcomes after a bariatric surgery. Journal of Gynecology Obstetrics and Human Reproduction
|
|
48(6): 401–405
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/30902762" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30902762</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Groth, S.W., Holland, M.L., Smith, J.A.
|
|
et al. (2017) Effect of Gestational Weight Gain and Pre-Pregnancy Body Mass Index in Adolescent Mothers on Weight and Body Mass Index of Adolescent Offspring. Journal of Adolescent Health
|
|
61(5): 626–633 [<a href="/pmc/articles/PMC5654683/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5654683</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28711316" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28711316</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Gu, Y., Lu, J., Liu, H.
|
|
et al. (2019) Joint Associations of Maternal Gestational Diabetes and Hypertensive Disorders of Pregnancy With Overweight in Offspring. Frontiers in Endocrinology
|
|
10: 645
|
|
[<a href="/pmc/articles/PMC6763696/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6763696</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/31616376" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31616376</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Guler, Tuba, Sivas, Filiz, Baskan, Bedriye Mermerci
|
|
et al. (2007) The effect of outfitting style on bone mineral density. Rheumatology international
|
|
27(8): 723–7
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17225054" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17225054</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Hantoushzadeh, S., Sheikh, M., Bosaghzadeh, Z.
|
|
et al. (2016) The impact of gestational weight gain in different trimesters of pregnancy on glucose challenge test and gestational diabetes. Postgraduate Medical Journal
|
|
92(1091): 520–524
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/26929392" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26929392</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not adjust for covariates in the analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Harita, N., Kariya, M., Hayashi, T.
|
|
et al. (2012) Gestational bodyweight gain among underweight Japanese women related to small-for-gestational-age birth. Journal of Obstetrics and Gynaecology Research
|
|
38(9): 1137–1144
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/22540915" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22540915</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
He, X.-J.; Dai, R.-X.; Hu, C.-L. (2020) Maternal pre-pregnancy overweight and obesity and the risk of preeclampsia: A meta - analysis of cohort studies. Obesity Research and Clinical Practice
|
|
14(1): 27–33
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/32035840" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32035840</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Heude, B, Thiebaugeorges, O, Goua, V
|
|
et al. (2012) Pre-pregnancy body mass index and weight gain during pregnancy: relations with gestational diabetes and hypertension, and birth outcomes. Maternal and child health journal
|
|
16(2): 355–63
|
|
[<a href="/pmc/articles/PMC3472402/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3472402</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/21258962" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21258962</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Hillier, T.A., Ogasawara, K.K., Pedula, K.L.
|
|
et al. (2020) Timing of Gestational Diabetes Diagnosis by Maternal Obesity Status: Impact on Gestational Weight Gain in a Diverse Population. Journal of Women’s Health
|
|
29(8): 1068–1076 [<a href="/pmc/articles/PMC7461990/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7461990</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32330405" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32330405</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not adjust for covariates in the analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Horosz, Edyta, Bomba-Opon, Dorota A, Szymanska, Monika
|
|
et al. (2013) Maternal weight gain in women with gestational diabetes mellitus. Journal of perinatal medicine
|
|
41(5): 523–8
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/23492551" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23492551</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Analysis not relevant to this protocol</p>
|
|
<p>
|
|
<i>Case series</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Huang, Yuan-Der, Luo, Yun-Ru, Lee, Meng-Chih
|
|
et al. (2022) Effect of maternal hypertensive disorders during pregnancy on offspring’s early childhood body weight: A population-based cohort study. Taiwanese journal of obstetrics & gynecology
|
|
61(5): 761–767
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/36088042" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 36088042</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factors are hypertensive disorders of pregnancy. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Hulsey, Thomas C, Neal, Diane, Bondo, Shana Catoe
|
|
et al. (2005) Maternal prepregnant body mass index and weight gain related to low birth weight in South Carolina. Southern medical journal
|
|
98(4): 411–5
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/15898514" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15898514</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not conduct multivariate regression analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Hung, T.-H.; Hsieh, T.-T.; Chen, S.-F. (2018) Risk of abnormal fetal growth in women with early- and late-onset preeclampsia. Pregnancy Hypertension
|
|
12: 201–206
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/29104027" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29104027</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Jin, Wen-Yuan, Lv, Yao, Bao, Yu
|
|
et al. (2016) Independent and Combined Effects of Maternal Pre-Pregnancy Body Mass Index and Gestational Weight Gain on Offspring Growth at 0 – 3 Years of Age. BioMed Research International
|
|
2016: 1–10 [<a href="/pmc/articles/PMC5019937/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5019937</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/27652262" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27652262</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Juhasz, G., Gyamfi, C., Gyamfi, P.
|
|
et al. (2005) Effect of body mass index and excessive weight gain on success of vaginal birth after cesarean delivery. Obstetrics and Gynecology
|
|
106(4): 741–746
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/16199630" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16199630</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Kawakita, T., Franco, S., Ghofranian, A.
|
|
et al. (2021) Interpregnancy Body Mass Index Change and Risk of Intrapartum Cesarean Delivery. American Journal of Perinatology
|
|
38(8): 759–765
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/33368071" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33368071</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Kawakita, Tetsuya, Downs, Sarah K, Franco, Stephanie
|
|
et al. (2022) Interpregnancy body mass index change and risk of hypertensive disorders in pregnancy. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|
|
35(17): 3223–3228 [<a href="https://pubmed.ncbi.nlm.nih.gov/32928011" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32928011</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Kiel, D.W., Dodson, E.A., Artal, R.
|
|
et al. (2007) Gestational weight gain and pregnancy outcomes in obese women: How much is enough?. Obstetrics and Gynecology
|
|
110(4): 752–758
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17906005" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17906005</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Analysis not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study data are presented graphically and insufficient information available to accurately extract raw data for analysis</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Kim, S.-Y., Hong, S.-Y., Kim, Y.
|
|
et al. (2021) Maternal pre-pregnancy body mass index and the risk for gestational diabetes mellitus in women with twin pregnancy in South Korea. Taiwanese Journal of Obstetrics and Gynecology
|
|
60(5): 863–868
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/34507662" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 34507662</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Kwon, Ha Yan, Kwon, Ja-Young, Park, Yong Won
|
|
et al. (2016) The risk of emergency cesarean section after failure of vaginal delivery according to pre-pregnancy body mass index or gestational weight gain by the 2009 Institute of Medicine guidelines. Obstetrics & gynecology science
|
|
59(3): 169–77
|
|
[<a href="/pmc/articles/PMC4871932/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4871932</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/27200306" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27200306</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in Korea</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Kyozuka, H., Jin, T., Fujimori, M.
|
|
et al. (2022) Effect of gestational weight gain on preeclampsia among underweight women: A single tertiary referral center study in Japanese women. Journal of Obstetrics and Gynaecology Research
|
|
48(5): 1141–1148
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/35246898" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35246898</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study does not report on information on the referent risk factor population</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Laitinen, J, Jaaskelainen, A, Hartikainen, A-L
|
|
et al. (2012) Maternal weight gain during the first half of pregnancy and offspring obesity at 16 years: a prospective cohort study. BJOG : an international journal of obstetrics and gynaecology
|
|
119(6): 716–23
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/22489762" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22489762</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Lau, E.Y., Archer, E., McDonald, S.M.
|
|
et al. (2014) Maternal weight gain in pregnancy and risk of obesity among offspring: A systematic review. Journal of Obesity
|
|
2014: 524939
|
|
[<a href="/pmc/articles/PMC4202338/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4202338</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25371815" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25371815</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Systematic review. Included studies checked for eligibility and included if relevant</p>
|
|
<p>
|
|
<i>No relevant studies identified</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Leng, Junhong, Li, Weiqin, Zhang, Shuang
|
|
et al. (2015) GDM Women’s Pre-Pregnancy Overweight/Obesity and Gestational Weight Gain on Offspring Overweight Status. PloS one
|
|
10(6): e0129536
|
|
[<a href="/pmc/articles/PMC4476720/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4476720</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26098307" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26098307</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Leonard, Stephanie A, Carmichael, Suzan L, Main, Elliott K
|
|
et al. (2020) Risk of severe maternal morbidity in relation to pre-pregnancy body mass index: Roles of maternal co-morbidities and caesarean birth. Paediatric and perinatal epidemiology
|
|
34(4): 460–468
|
|
[<a href="/pmc/articles/PMC6864221/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6864221</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/31106879" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31106879</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Lewandowska, M.; Wieckowska, B.; Sajdak, S. (2020) Pre-pregnancy obesity, excessive gestational weight gain, and the risk of pregnancy-induced hypertension and gestational diabetes mellitus. Journal of Clinical Medicine
|
|
9(6): 1–13 [<a href="/pmc/articles/PMC7355601/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7355601</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32599847" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32599847</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study did not adjust for covariates in the analysis</p>
|
|
<p>
|
|
<i>Relevant effect estimates (OR) were not adjusted for covariates. Analyses adjusted for covariates were reported as AUC, which is not a relevant outcome in the review protocol</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Lewandowska, M., Wieckowska, B., Sajdak, S.
|
|
et al. (2020) Pre-pregnancy obesity vs. Other risk factors in probability models of preeclampsia and gestational hypertension. Nutrients
|
|
12(9): 1–19 [<a href="/pmc/articles/PMC7551880/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7551880</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32887442" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32887442</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p>
|
|
<i>Case-control study design</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Li, M.; Zhang, C.-Y.; Yue, C.-Y. (2022) Effects of pre-pregnancy BMI and gestational weight gain on adverse pregnancy outcomes and complications of GDM. Journal of Obstetrics and Gynaecology
|
|
42(4): 630–635
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/35469531" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35469531</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Liang, Z., Liu, H., Wang, L.
|
|
et al. (2020) Maternal Gestational Diabetes Mellitus Modifies the Relationship Between Genetically Determined Body Mass Index During Pregnancy and Childhood Obesity. Mayo Clinic Proceedings
|
|
95(9): 1877–1887
|
|
[<a href="/pmc/articles/PMC7672776/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7672776</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32861332" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32861332</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is gestational diabetes mellitus. No gestational weight gain was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Liu, L.Y.; Zafman, K.B.; Fox, N.S. (2021) Weight gain and pregnancy outcomes in overweight or obese women with twin gestations. Journal of Maternal-Fetal and Neonatal Medicine
|
|
34(11): 1774–1779
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/31379228" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31379228</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Studies from a systematic review that is included</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Loh, H.H.; Taipin, H.; Said, A. (2021) The effect of obesity in pregnancy and gestational weight gain on neonatal outcome in glucose-tolerant mothers. Obesity Science and Practice
|
|
7(4): 425–431
|
|
[<a href="/pmc/articles/PMC8346371/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8346371</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/34401200" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 34401200</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in Malaysia</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Longmore, Danielle K, Barr, Elizabeth L M, Lee, I-Lynn
|
|
et al. (2019) Maternal body mass index, excess gestational weight gain, and diabetes are positively associated with neonatal adiposity in the Pregnancy and Neonatal Diabetes Outcomes in Remote Australia (PANDORA) study. Pediatric obesity
|
|
14(4): e12490
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/30650263" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30650263</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p><i>Study reported on neonatal length, head circumference, sum of skinfolds, total body fat, and percentage body fat</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Lucovnik, M., Blickstein, I., Verdenik, I.
|
|
et al. (2015) Maternal obesity in singleton versus twin gestations: A population-based matched case-control study. Journal of Maternal-Fetal and Neonatal Medicine
|
|
28(6): 623–625
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/24866350" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24866350</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p>
|
|
<i>Case-control study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Lucovnik, M., Tul, N., Verdenik, I.
|
|
et al. (2012) Risk factors for preeclampsia in twin pregnancies: A population-based matched case-control study. Journal of Perinatal Medicine
|
|
40(4): 379–382
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/22752768" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22752768</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p>
|
|
<i>Case-control study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Lucovnik, Miha, Blickstein, Isaac, Verdenik, Ivan
|
|
et al. (2014) Impact of pre-gravid body mass index and body mass index change on preeclampsia and gestational diabetes in singleton and twin pregnancies. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|
|
27(18): 1901–4 [<a href="https://pubmed.ncbi.nlm.nih.gov/24506066" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24506066</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not adjust for covariates in the analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Macdonald-Wallis, Corrie, Tilling, Kate, Fraser, Abigail
|
|
et al. (2013) Gestational weight gain as a risk factor for hypertensive disorders of pregnancy. American journal of obstetrics and gynecology
|
|
209(4): 327e1–17 [<a href="/pmc/articles/PMC3807791/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3807791</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23711667" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23711667</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
MacRI, F., Pitocco, D., Di Pasquo, E.
|
|
et al. (2018) Gestational weight gain as an independent risk factor for adverse pregnancy outcomes in women with gestational diabetes. European Review for Medical and Pharmacological Sciences
|
|
22(14): 4403–4410
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/30058672" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30058672</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Study did not adjust for covariates in the analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Maeda, Y., Ogawa, K., Morisaki, N.
|
|
et al. (2022) The association between gestational weight gain and perinatal outcomes among underweight women with twin pregnancy in Japan. International Journal of Gynecology and Obstetrics
|
|
159(2): 420–426
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/35094398" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35094398</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Data presented graphically and cannot be extracted for analysis</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
May, R. (2007) Pre-Pregnancy weight, inappropriate gestational weight gain, and smoking: Relationships to birth weight. American Journal of Human Biology
|
|
19(3): 305–310
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/17421006" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17421006</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Analysis not relevant to this protocol</p>
|
|
<p><i>Multiple regression analysis was used. Data reporting association between risk factor and maternal/fetal/neonatal outcomes not reported</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
McDonald, ACE; Wise, MR; Thompson, JM (2018) Effect of excessive gestational weight gain on trial of labour after caesarean: A retrospective cohort study. The Australian & New Zealand journal of obstetrics & gynaecology
|
|
58(1): 64–71
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/28730610" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28730610</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Conference abstract.</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
McDonald, Sarah D, Woolcott, Christy, Chapinal, Nuria
|
|
et al. (2018) Interprovincial variation in pre-pregnancy body mass index and gestational weight gain and their impact on neonatal birth weight with respect to small and large for gestational age. Canadian journal of public health = Revue canadienne de sante publique
|
|
109(4): 527–538
|
|
[<a href="/pmc/articles/PMC6964407/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6964407</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30191462" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30191462</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Meinich, T. and Trovik, J. (2020) Early maternal weight gain as a risk factor for SGA in pregnancies with hyperemesis gravidarum: A 15-year hospital cohort study. BMC Pregnancy and Childbirth
|
|
20(1): 255
|
|
[<a href="/pmc/articles/PMC7189646/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7189646</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/32345259" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32345259</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor are women with hyperemesis gravidarum who regained their pre-pregnancy BMI</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Miao, Miao, Dai, Mei, Zhang, Yue
|
|
et al. (2017) Influence of maternal overweight, obesity and gestational weight gain on the perinatal outcomes in women with gestational diabetes mellitus. Scientific reports
|
|
7(1): 305
|
|
[<a href="/pmc/articles/PMC5428436/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5428436</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28331199" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28331199</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Mourtakos, S P, Tambalis, K D, Panagiotakos, D B
|
|
et al. (2017) Association between gestational weight gain and risk of obesity in preadolescence: a longitudinal study (1997-2007) of 5125 children in Greece. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
|
|
30(1): 51–58
|
|
[<a href="/pmc/articles/PMC5225238/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5225238</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/27412890" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27412890</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p>
|
|
<i>Outcomes are not reported as a summary estimate as specified in the protocol</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Najafi, F., Hasani, J., Izadi, N.
|
|
et al. (2019) The effect of pre-pregnancy body mass index on the risk of gestational diabetes mellitus: A systematic review and dose-response meta-analysis. Obesity Reviews
|
|
20(3): 472–486
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/30536891" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30536891</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Nakanishi, K., Saijo, Y., Yoshioka, E.
|
|
et al. (2022) Severity of low pre-pregnancy body mass index and perinatal outcomes: the Japan Environment and Children’s Study. BMC Pregnancy and Childbirth
|
|
22(1): 121
|
|
[<a href="/pmc/articles/PMC8840606/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8840606</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/35148693" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35148693</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight gain was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Okah, Felix A, Cai, Jinwen, Dew, Paul C
|
|
et al. (2010) Risk factors for recurrent small-for-gestational-age birth. American journal of perinatology
|
|
27(1): 1–7
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/19670131" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19670131</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study did not adjust for covariates in the analysis</p>
|
|
<p>
|
|
<i>Weight change in relation to SGA not reported in multivariate analysis</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Oken, Emily, Taveras, Elsie M, Kleinman, Ken P
|
|
et al. (2007) Gestational weight gain and child adiposity at age 3 years. American journal of obstetrics and gynecology
|
|
196(4): 322e1–8 [<a href="/pmc/articles/PMC1899090/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1899090</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/17403405" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17403405</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Voerman 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Olmos, Pablo Roberto, Borzone, Gisella Rosa, Olmos, Roberto Ignacio
|
|
et al. (2012) Gestational diabetes and pre-pregnancy overweight: possible factors involved in newborn macrosomia. The journal of obstetrics and gynaecology research
|
|
38(1): 208–14
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/22070342" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22070342</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in Chile</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Olson, C.M.; Strawderman, M.S.; Dennison, B.A. (2009) Maternal weight gain during pregnancy and child weight at age 3 years. Maternal and Child Health Journal
|
|
13(6): 839–846
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/18818995" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18818995</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ouzounian, J.G., Hernandez, G.D., Korst, L.M.
|
|
et al. (2011) Pre-pregnancy weight and excess weight gain are risk factors for macrosomia in women with gestational diabetes. Journal of Perinatology
|
|
31(11): 717–721
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/21372797" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21372797</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Paramsothy, Pathmaja, Lin, Yvonne S, Kernic, Mary A
|
|
et al. (2009) Interpregnancy weight gain and cesarean delivery risk in women with a history of gestational diabetes. Obstetrics and gynecology
|
|
113(4): 817–823
|
|
[<a href="/pmc/articles/PMC2743407/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2743407</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19305325" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19305325</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a id="niceng247er6.appj.ref115"></a>Pecheux, Oceane, Garabedian, Charles, Drumez, Elodie
|
|
et al. (2019) Maternal and neonatal outcomes according to gestational weight gain in twin pregnancies: Are the Institute of Medicine guidelines associated with better outcomes?. European journal of obstetrics, gynecology, and reproductive biology
|
|
234: 190–194
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/30710766" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30710766</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Studies from a systematic review that is included</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Pettersen-Dahl, Anita, Murzakanova, Gulim, Sandvik, Leiv
|
|
et al. (2018) Maternal body mass index as a predictor for delivery method. Acta obstetricia et gynecologica Scandinavica
|
|
97(2): 212–218
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/29164597" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29164597</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Pezzarossa, A, Orlandi, N, Baggi, V
|
|
et al. (1996) Effects of maternal weight variations and gestational diabetes mellitus on neonatal birth weight. Journal of diabetes and its complications
|
|
10(2): 78–83
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/8777334" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8777334</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Population not relevant to this protocol</p>
|
|
<p><i>Study reported on pregnant women diagnosed with gestational diabetes</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Phaloprakarn, C. and Tangjitgamol, S. (2020) Risk score for predicting primary cesarean delivery in women with gestational diabetes mellitus. BMC Pregnancy and Childbirth
|
|
20(1): 607
|
|
[<a href="/pmc/articles/PMC7545573/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7545573</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/33032545" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33032545</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in Thailand</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Pham, Michelle T, Brubaker, Katherine, Pruett, Kimberly
|
|
et al. (2013) Risk of childhood obesity in the toddler offspring of mothers with gestational diabetes. Obstetrics and gynecology
|
|
121(5): 976–982
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/23635733" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23635733</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Population not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study reported on children whose mothers were diagnosed with gestational diabetes during their pregnancy with that child</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Poorolajal, Jalal and Jenabi, Ensiyeh (2016) The association between body mass index and preeclampsia: a meta-analysis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|
|
29(22): 3670–6 [<a href="https://pubmed.ncbi.nlm.nih.gov/26762770" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26762770</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Pugh, Sarah J, Hinkle, Stefanie N, Kim, Sungduk
|
|
et al. (2018) Combined Influence of Gestational Weight Gain and Estimated Fetal Weight on Risk Assessment for Small- or Large-for-Gestational-Age Birth Weight: A Prospective Cohort Study. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
|
|
37(4): 935–940
|
|
[<a href="/pmc/articles/PMC6065252/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6065252</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28960393" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28960393</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ramos-Levi, A.M., Fernandez-Pombo, A., Garcia-Fontao, C.
|
|
et al. (2022) Gestational weight gain influences neonatal outcomes in women with obesity and gestational diabetes. Endocrinologia, Diabetes y Nutricion [<a href="https://pubmed.ncbi.nlm.nih.gov/36526355" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 36526355</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p>
|
|
<i>Outcomes are not reported as a summary estimate as specified in the protocol</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ray, J.G., Vermeulen, M.J., Shapiro, J.L.
|
|
et al. (2001) Maternal and neonatal outcomes in pregestational and gestational diabetes mellitus, and the influence of maternal obesity and weight gain: The DEPOSIT study. QJM - Monthly Journal of the Association of Physicians
|
|
94(7): 347–356
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/11435630" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11435630</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Population not relevant to this protocol</p>
|
|
<p><i>Study reported on pregnant women diagnosed with gestational diabetes</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Restall, A., Taylor, R.S., Thompson, J.M.D.
|
|
et al. (2014) Risk factors for excessive gestational weight gain in a healthy, nulliparous cohort. Journal of Obesity
|
|
2014: 148391
|
|
[<a href="/pmc/articles/PMC4065732/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4065732</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24995130" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24995130</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Ricci, Elena, Parazzini, Fabio, Chiaffarino, Francesca
|
|
et al. (2010) Pre-pregnancy body mass index, maternal weight gain during pregnancy and risk of small-for-gestational age birth: results from a case-control study in Italy. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|
|
23(6): 501–5 [<a href="https://pubmed.ncbi.nlm.nih.gov/19724969" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19724969</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p>
|
|
<i>Case-control study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Rosett, H., Siegel, A.M., Tucker, A.
|
|
et al. (2022) The impact of excessive gestational weight gain timing on neonatal outcomes in women with class III obesity. Journal of Maternal-Fetal and Neonatal Medicine
|
|
35(16): 3059–3063
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/32752955" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 32752955</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p><i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Saftlas, Wang, Risch
|
|
et al. (2000) Pre-Pregnancy body mass index and gestational weight gain as risk factors for preeclampsia and transient hypertension. Annals of epidemiology
|
|
10(7): 475 [<a href="https://pubmed.ncbi.nlm.nih.gov/11018413" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11018413</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Conference abstract.</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Schack-Nielsen, L., Michaelsen, K.F., Gamborg, M.
|
|
et al. (2010) Gestational weight gain in relation to offspring body mass index and obesity from infancy through adulthood. International Journal of Obesity
|
|
34(1): 67–74
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/19918246" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19918246</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Population not relevant to this protocol</p>
|
|
<p>
|
|
<i>Birth cohort between 1959 and 1961. This review protocol was restricted to studies from 1970</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Shin, Dayeon and Song, Won O (2015) Pre-Pregnancy body mass index is an independent risk factor for gestational hypertension, gestational diabetes, preterm labor, and small- and large-for-gestational-age infants. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|
|
28(14): 1679–86 [<a href="https://pubmed.ncbi.nlm.nih.gov/25211384" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25211384</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Simas, Tiffany A Moore, Waring, Molly E, Liao, Xun
|
|
et al. (2012) Pre-Pregnancy weight, gestational weight gain, and risk of growth affected neonates. Journal of women’s health (2002)
|
|
21(4): 410–7 [<a href="https://pubmed.ncbi.nlm.nih.gov/22165953" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22165953</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Simmons, D, Devlieger, R, van Assche, A
|
|
et al. (2018) Association between Gestational Weight Gain, Gestational Diabetes Risk, and Obstetric Outcomes: A Randomized Controlled Trial Post Hoc Analysis. Nutrients
|
|
10(11) [<a href="/pmc/articles/PMC6266006/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6266006</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30360536" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30360536</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p><i>Randomised controlled trial</i>.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Stamnes Kopp, U M, Dahl-Jorgensen, K, Stigum, H
|
|
et al. (2012) The associations between maternal pre-pregnancy body mass index or gestational weight change during pregnancy and body mass index of the child at 3 years of age. International journal of obesity (2005)
|
|
36(10): 1325–31
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/22929211" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22929211</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Outcome(s) not relevant to this protocol</p>
|
|
<p>
|
|
<i>The study reports a combined effect of gestational weight change and expected BMI in children at 3 years, which is not of use for this review</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Swank, M.L., Caughey, A.B., Farinelli, C.K.
|
|
et al. (2014) The impact of change in pregnancy body mass index on the development of gestational hypertensive disorders. Journal of Perinatology
|
|
34(3): 181–185
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/24384780" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24384780</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Tabet, M., Harper, L.M., Flick, L.H.
|
|
et al. (2017) Gestational Weight Gain in the First Two Pregnancies and Perinatal Outcomes in the Second Pregnancy. Paediatric and Perinatal Epidemiology
|
|
31(4): 304–313
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/28543169" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28543169</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Takimoto, H., Sugiyama, T., Nozue, M.
|
|
et al. (2011) Maternal antenatal body mass index gains as predictors of large-for-gestational-age infants and cesarean deliveries in Japanese singleton pregnancies. Journal of Obstetrics and Gynaecology Research
|
|
37(6): 553–562
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/21375666" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21375666</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Analysis not relevant to this protocol</p>
|
|
<p>
|
|
<i>Study data are presented graphically and insufficient information available to accurately extract raw data for analysis</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Teshome, A.A., Li, Q., Garoma, W.
|
|
et al. (2021) Gestational diabetes mellitus, pre-pregnancy body mass index and gestational weight gain predicts fetal growth and neonatal outcomes. Clinical Nutrition ESPEN
|
|
42: 307–312
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/33745597" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33745597</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Vahratian, A., Siega-Riz, A.M., Savitz, D.A.
|
|
et al. (2005) Maternal pre-pregnancy overweight and obesity and the risk of cesarean delivery in nulliparous women. Annals of Epidemiology
|
|
15(7): 467–474
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/15921926" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15921926</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Von Kries, R., Ensenauer, R., Beyerlein, A.
|
|
et al. (2011) Gestational weight gain and overweight in children: Results from the cross-sectional German KiGGS study. International Journal of Pediatric Obesity
|
|
6(1): 45–52
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/20441556" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20441556</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study design does not match protocol</p>
|
|
<p>
|
|
<i>Cross-sectional study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Voskamp, BJ, Kazemier, BM, Ravelli, ACJ
|
|
et al. (2013) Recurrence of small-for gestational-age pregnancy: analysis of first and subsequent singleton pregnancies in the Netherlands. American journal of obstetrics and gynecology
|
|
208(5): 374.e1–374.e6 [<a href="https://pubmed.ncbi.nlm.nih.gov/23419319" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23419319</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight change was reported by the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Wang, F., Liang, Z.X., Mao, W.R.
|
|
et al. (2020) Influence of pre-pregnancy body mass index and gestational weight gain in twin pregnancies on blood glucose, serum lipid and perinatal outcomes. Clinical and Experimental Obstetrics and Gynecology
|
|
47(3): 376–382
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Watanabe, Hiroko, Inoue, Kazuko, Doi, Masako
|
|
et al. (2010) Risk factors for term small for gestational age infants in women with low pre-pregnancy body mass index. The journal of obstetrics and gynaecology research
|
|
36(3): 506–12
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/20598029" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20598029</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Risk factor does not match protocol</p>
|
|
<p>
|
|
<i>Risk factor is pre-pregnancy BMI. No gestational weight gain was reported in the study</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Wei, X., Shen, S., Huang, P.
|
|
et al. (2022) Gestational weight gain rates in the first and second trimesters are associated with small for gestational age among underweight women: a prospective birth cohort study. BMC Pregnancy and Childbirth
|
|
22(1): 106
|
|
[<a href="/pmc/articles/PMC8818159/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8818159</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/35123424" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35123424</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Weschenfelder, F., Lehmann, T., Schleussner, E.
|
|
et al. (2019) Gestational Weight Gain Particularly Affects the Risk of Large for Gestational Age Infants in Non-obese Mothers. Geburtshilfe und Frauenheilkunde
|
|
79(11): 1183–1190
|
|
[<a href="/pmc/articles/PMC6846725/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6846725</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/31736507" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31736507</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Wrotniak, BH, Shults, J, Butts, S
|
|
et al. (2008) Gestational weight gain and risk of overweight in the offspring at age 7 y in a multicenter, multiethnic cohort study. The American journal of clinical nutrition
|
|
87(6): 1818–24
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/18541573" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18541573</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref37" rid="niceng247er6.s1.ref37">Voerman 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Xu, H., Hutcheon, J.A., Liu, X.
|
|
et al. (2022) Risk of gestational diabetes mellitus in relation to early pregnancy and gestational weight gain before diagnosis: A population-based cohort study. Acta Obstetricia et Gynecologica Scandinavica [<a href="/pmc/articles/PMC9812107/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC9812107</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/36069213" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 36069213</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">- Population and outcomes fully overlap with <a class="bibr" href="#niceng247er6.s1.ref34" rid="niceng247er6.s1.ref34">Santos 2019</a> IPD, which included birth cohorts from Europe, North America, and Oceania published before 2019</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Yuanmei, L., Qian, Z., Fengsen, X.
|
|
et al. (2019) Restricted gestational weight gain in overweight/obese women with gestational diabetes mellitus and pregnancy outcomes. Clinical and Experimental Obstetrics and Gynecology
|
|
46(5): 763–769
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Zhang, X. and Xiao, Y. (2019) The Association Between Trimester-Specific Weight Gain and Severe Preeclampsia/Adverse Perinatal Outcome in Gestational Diabetes Mellitus Complicated by Preeclampsia: A Retrospective Case Study. Diabetes Therapy
|
|
10(2): 725–734
|
|
[<a href="/pmc/articles/PMC6437224/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6437224</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30838548" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30838548</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
|
|
</p>
|
|
</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Zheng, W., Huang, W., Liu, C.
|
|
et al. (2021) Weight gain after diagnosis of gestational diabetes mellitus and its association with adverse pregnancy outcomes: a cohort study. BMC Pregnancy and Childbirth
|
|
21(1): 216
|
|
[<a href="/pmc/articles/PMC7971950/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7971950</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/33731035" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33731035</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>- Study conducted in an OECD low-middle income country</p>
|
|
<p>
|
|
<i>Study conducted in China</i>
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</p>
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</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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Zhong, C., Li, X., Chen, R.
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et al. (2017) Greater early and mid-pregnancy gestational weight gain are associated with increased risk of gestational diabetes mellitus: A prospective cohort study. Clinical Nutrition ESPEN
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22: 48–53
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|
[<a href="https://pubmed.ncbi.nlm.nih.gov/29415834" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29415834</span></a>]
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</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>- Study conducted in an OECD low-middle income country</p>
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<p>
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<i>Study conducted in China</i>
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</p>
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</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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|
<a id="niceng247er6.appj.ref150"></a>Zhong, W., Fan, X., Hu, F.
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et al. (2021) Gestational Weight Gain and Its Effects on Maternal and Neonatal Outcome in Women With Twin Pregnancies: A Systematic Review and Meta-Analysis. Frontiers in Pediatrics
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9: 674414
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|
[<a href="/pmc/articles/PMC8298912/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8298912</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/34307252" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 34307252</span></a>]
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</td><td headers="hd_h_niceng247er6.appj.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>- Systematic review. Included studies checked for eligibility and included if relevant</p>
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<p><i>Relevant studies have been included in the systematic review by</i>
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<a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>. <a class="bibr" href="#niceng247er6.s1.ref38" rid="niceng247er6.s1.ref38">Whitaker 2022</a>
|
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<i>was prioritised over</i>
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<a class="bibr" href="#niceng247er6.appj.ref150" rid="niceng247er6.appj.ref150">Zhong 2021</a>
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|
<i>for inclusion as it covered the same population and outcomes, but included a larger number of studies</i></p>
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</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">AUC: area under the curve; BMI: body mass index; IPD: individual patient data; OECD: Organisation for Economic Co-operation and Development; OR: odds ratio</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng247er6appjtab2"><div id="niceng247er6.appj.tab2" class="table"><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK612413/table/niceng247er6.appj.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng247er6.appj.tab2_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reason for exclusion</th></tr></thead><tbody><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Azher, S., Pinheiro, J.M.B., Philbin, B.
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|
et al. (2022) The Impact of Maternal Obesity on NICU and Newborn Nursery Costs. Frontiers in Pediatrics
|
|
10: 863165
|
|
[<a href="/pmc/articles/PMC9157567/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC9157567</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/35664876" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 35664876</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Costs linked to gestational BMI at birth and not to gestational weight change</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Denison, F.C., Norrie, G., Graham, B.
|
|
et al. (2009) Increased maternal BMI is associated with an increased risk of minor complications during pregnancy with consequent cost implications. BJOG: An International Journal of Obstetrics and Gynaecology
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116(11): 1467–1472
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|
[<a href="https://pubmed.ncbi.nlm.nih.gov/19496775" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19496775</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Costs linked to gestational BMI at first antenatal appointment, and not to gestational weight change</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Denison, F.C., Norwood, P., Bhattacharya, S.
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|
et al. (2014) Association between maternal body mass index during pregnancy, short-term morbidity, and increased health service costs: A population-based study. BJOG: An International Journal of Obstetrics and Gynaecology
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121(1): 72–82
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/24102880" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24102880</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Costs linked to gestational BMI measured prior to 16 weeks of gestation, and not to gestational weight change</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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|
Lenoir-Wijnkoop, I., van der Beek, E.M., Garssen, J.
|
|
et al. (2015) Health economic modeling to assess short-term costs of maternal overweight, gestational diabetes, and related macrosomia - a pilot evaluation. Frontiers in Pharmacology
|
|
6(may): 103
|
|
[<a href="/pmc/articles/PMC4438224/" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4438224</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26042038" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26042038</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No comparison group; only costs associated with overweight reported</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Liang, Ching-Chung, Chao, Minston, Chang, Shuenn-Dhy
|
|
et al. (2021) Pregnancy weight gain may affect perinatal outcomes, quality of life during pregnancy, and child-bearing expenses: an observational cohort study. Archives of gynecology and obstetrics
|
|
304(3): 599–608
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/33665682" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33665682</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None OECD country (Taiwan)</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Rowlands, I., Graves, N., de Jersey, S.
|
|
et al. (2010) Obesity in pregnancy: outcomes and economics. Seminars in Fetal and Neonatal Medicine
|
|
15(2): 94–99
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/19819773" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19819773</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review; no costs reported</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Trasande, Leonardo, Lee, Menjean, Liu, Yinghua
|
|
et al. (2009) Incremental charges, costs, and length of stay associated with obesity as a secondary diagnosis among pregnant women. Medical care
|
|
47(10): 1046–52
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/19820612" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19820612</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Costs linked to obesity status during pregnancy, and not to gestational weight change</td></tr><tr><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
Whiteman, V.E., Salemi, J.L., Mejia De Grubb, M.C.
|
|
et al. (2015) Additive effects of Pre-pregnancy body mass index and gestational diabetes on health outcomes and costs. Obesity
|
|
23(11): 2299–2308
|
|
[<a href="https://pubmed.ncbi.nlm.nih.gov/26390841" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26390841</span></a>]
|
|
</td><td headers="hd_h_niceng247er6.appj.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Costs linked to pre-pregnancy BMI, and not to gestational weight change</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">BMI: body mass index; OECD: Organisation for Economic Co-operation and Development</p></div></dd></dl></dl></div></div></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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