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class="title" itemprop="name">Cefalexina (Keflex®, Keftab®)</span></h1><p class="fm-aai"><a href="#_NBK609802_pubdet_">Publication Details</a></p></div></div><div class="body-content whole_rhythm" itemprop="text"><div id="cephalexin-sp.cephalexin-sp_s_001"><div class="h2"></div><p>Esta hoja trata sobre la exposición a cefalexina en el embarazo y durante la lactancia. Esta información se basa en la literatura publicada disponible. No debe usarse como un sustituto de la atención médica o los consejos de su proveedor de atención de salud.</p><p>
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<b>
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<i>¿Qué es la cefalexina?</i>
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</b>
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</p><blockquote><p>La cefalexina es un medicamento antibiótico que se ha utilizado para tratar infecciones como Staphylococcus aureus (estafilococos) y Escherichia coli (E. coli). Algunas marcas de cefalexina son Keflex® y Keftab®.</p><p>A veces, cuando las personas se enteran de que están embarazadas, piensan en cambiar la forma de tomar sus medicamentos o dejar de tomarlos por completo. Sin embargo, es importante hablar con sus proveedores de atención de salud antes de realizar cambios en la forma en que toma su medicamento. Sus proveedores de atención de salud pueden hablar con usted sobre los beneficios de tratar su afección y los riesgos de enfermedad no tratada durante el embarazo.</p><p>Tener ciertas infecciones (como una infección por estafilococos o E. coli) durante el embarazo puede aumentar la probabilidad de problemas o infecciones relacionados con el embarazo en un bebé recién nacido. MotherToBaby tiene hojas informativas sobre las infecciones por estafilococos y E. coli aquí: <a href="https://mothertobaby.org/es/hojas-informativas/estafilococo-aureus/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://mothertobaby.org/es/hojas-informativas/estafilococo-aureus/</a> y <a href="https://mothertobaby.org/es/hojas-informativas/e-coli/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://mothertobaby.org/es/hojas-informativas/e-coli/</a>.</p></blockquote><p>
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<b>
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<i>Tomo cefalexina. ¿Puede hacer que me resulte más difícil quedar embarazada?</i>
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</b>
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</p><blockquote><p>No se han realizado estudios en humanos para ver si la cefalexina puede dificultar el embarazo. En estudios con animales, la cefalexina no afectó la fertilidad (capacidad de quedar embarazada).</p></blockquote><p>
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<b>
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<i>¿Tomar cefalexina aumenta la probabilidad de aborto espontáneo?</i>
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</b>
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</p><blockquote><p>El aborto espontáneo es común y puede ocurrir en cualquier embarazo por muchas razones diferentes. En un estudio de 262 personas que tomaron cefalexina durante el embarazo, no hubo un aumento en los abortos espontáneos en comparación con un grupo similar de personas que no tomaron cefalexina.</p></blockquote><p>
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<b>
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<i>¿Tomar cefalexina aumenta la probabilidad de defectos de nacimiento?</i>
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</b>
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</p><blockquote><p>Cada embarazo comienza con un 3-5% de probabilidad de tener un defecto de nacimiento. Esto se conoce como riesgo de fondo. La información sobre el uso de cefalexina durante el embarazo es limitada. En un estudio de 262 personas que tomaron cefalexina durante el embarazo, no hubo un aumento en la probabilidad de defectos de nacimiento por encima del riesgo de fondo.</p></blockquote><p>
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<b>
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<i>¿Tomar cefalexina durante el embarazo aumenta la probabilidad de otros problemas relacionados con el embarazo?</i>
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</b>
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</p><blockquote><p>No se han realizado estudios para ver si la cefalexina aumenta la probabilidad de problemas relacionados con el embarazo, como parto prematuro (parto antes de la semana 37) o bajo peso al nacer (que pesa menos de 5 libras, 8 onzas [2500 gramos] al nacer).</p></blockquote><p>
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<b>
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<i>¿Tomar cefalexina durante el embarazo afecta el comportamiento o aprendizaje futuro para el niño?</i>
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</b>
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</p><blockquote><p>No se han realizado estudios para ver si la cefalexina puede causar problemas de comportamiento o aprendizaje en el niño.</p><p>
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<b>La lactancia mientras tomar <i>cefalexina</i>:</b>
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</p><p>La cefalexina pasa a la leche materna en pequeñas cantidades. En los informes de 20 bebés expuestos a la cefalexina a través de la leche materna, 4 tuvieron diarrea. Hay un informe de un bebé que tuvo sarpullido después de ser amamantado, debido a una sensibilidad a la cefalexina. Si sospecha que el bebé tiene algún síntoma (como diarrea o sarpullido), comuníquese con el proveedor de atención de salud del niño. Asegúrese de hablar con su proveedor de atención de salud acerca de todas sus preguntas sobre la lactancia.</p></blockquote><p>
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<b>
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<i>Si un hombre toma cefalexina, ¿podría afectar la fertilidad (capacidad de embarazar a la pareja) o aumentar la probabilidad de defectos de nacimiento?</i>
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</b>
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</p><blockquote><p>No se han realizado estudios para ver si la cefalexina podría afectar la fertilidad masculina (capacidad de embarazar a la pareja) o aumentar la probabilidad de defectos de nacimiento por encima del riesgo de fondo. Algunas infecciones, como el estafilococo o la E. coli, pueden afectar la fertilidad masculina. En general, es poco probable que las exposiciones que tienen los padres o donantes de esperma aumenten los riesgos de un embarazo. Para más información, consulte la hoja informativa de MotherToBaby acerca de Exposiciones Paternas en <a href="https://mothertobaby.org/es/hojas-informativas/exposiciones-paternas/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://mothertobaby.org/es/hojas-informativas/exposiciones-paternas/</a>.</p></blockquote></div><div id="R001"><h2 id="_R001_">Referencias Seleccionadas:</h2><ul class="simple-list"><li class="half_rhythm"><p><div class="bk_ref" id="c028">Benyamini
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L, et al. 2005. The safety of amoxicillin/clavulanic acid and cefuroxime during lactation.
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Ther Drug Monit.
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27:499–502. [<a href="https://pubmed.ncbi.nlm.nih.gov/16044108" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16044108</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="c029">Chu
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YN, et al. 2019. Toxic epidermal necrolysis in an infant induced by drug intake through breast milk.
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Dermatologica Sinica.
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37:86–89.</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="c030">Czeizel
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AE, et al. 2001. Use of cephalosporins during pregnancy and in the presence of congenital anomalies: a population-based, case-control study.
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Am J Obstet Gynecol
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184:1289-1896. [<a href="https://pubmed.ncbi.nlm.nih.gov/11349204" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11349204</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="c031">Ilett
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KF, et al. 2006. Transfer of probenecid and cephalexin into breast milk.
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Ann Pharmacother.
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40:986–989. [<a href="https://pubmed.ncbi.nlm.nih.gov/16551765" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16551765</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="c032">Ito
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S, et al. 1993. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication.
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Am J Obstet Gynecol.
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168:1393–1399. [<a href="https://pubmed.ncbi.nlm.nih.gov/8498418" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8498418</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="c033">Kafetzi
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D, et al. 1981. Passage of cephalosporins and amoxicillin into the breast milk.
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Acta Paediatr Scand
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70:285-288. [<a href="https://pubmed.ncbi.nlm.nih.gov/7246123" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 7246123</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="c034">Teva
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Pharmaceuticals.
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2020. Cephalexin product label. Available at: <a href="https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=19307ff0-71de-477b-965d-ea243e5ede3a" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://dailymed<wbr style="display:inline-block"></wbr>​.nlm<wbr style="display:inline-block"></wbr>​.nih.gov/dailymed/drugInfo<wbr style="display:inline-block"></wbr>​.cfm?setid=19307ff0-71de-477b-965d-ea243e5ede3a</a>. [Accessed March 27 2024].</div></p></li></ul></div></div></div><div class="fm-sec"><h2 id="_NBK609802_pubdet_">Publication Details</h2><h3>Publication History</h3><p class="small">Published online: April 2024.</p><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> de OTIS, abril 2024.<p class="small">This work is available under the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported license (<a href="https://creativecommons.org/licenses/by-nc-nd/3.0/" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=uri">CC BY-NC-ND 3.0</a>)</p></div></div><h3>Publisher</h3><p><a href="https://mothertobaby.org/fact-sheets/" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">Organization of Teratology Information Specialists (OTIS)</a>, Brentwood (TN)</p><h3>NLM Citation</h3><p>Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Cefalexina (Keflex®, Keftab®) 2024 Apr.<span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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