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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. </p></div><div class="iconblock clearfix whole_rhythm no_top_margin bk_noprnt"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/mtb/"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-mtb-lrg.png" alt="Cover of Mother To Baby | Fact Sheets" height="100px" width="80px" /></a><div class="icnblk_cntnt eight_col"><h2>Mother To Baby | Fact Sheets [Internet].</h2><a data-jig="ncbitoggler" href="#__NBK605064_dtls__">Show details</a><div style="display:none" class="ui-widget" id="__NBK605064_dtls__"><div>Brentwood (TN): <a href="https://mothertobaby.org/fact-sheets/" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">Organization of Teratology Information Specialists (OTIS)</a>; 1994-.</div></div><div class="half_rhythm"></div><div class="bk_noprnt"><form method="get" action="/books/n/mtb/" id="bk_srch"><div class="bk_search"><label for="bk_term" class="offscreen_noflow">Search term</label><input type="text" title="Search this book" id="bk_term" name="term" value="" data-jig="ncbiclearbutton" /> <input type="submit" class="jig-ncbibutton" value="Search this book" submit="false" style="padding: 0.1em 0.4em;" /></div></form></div></div></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK605064_"><span class="title" itemprop="name">Clotrimazol</span></h1><p class="small">Published online: October 2023.</p></div><div class="body-content whole_rhythm" itemprop="text"><div id="clotrimazole-sp.clotrimazole-sp_s_001"><div class="h2"></div><p>Esta hoja trata sobre la exposición a clotrimazol en el embarazo y durante la lactancia. Esta información se basa en la literatura publicada disponible. No debe usarse como un sustituto de la atención médica o los consejos de su proveedor de atención de salud.</p><p>
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<b>
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<i>¿Qué es el clotrimazol?</i>
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</b>
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</p><blockquote><p>El clotrimazol es un medicamento que se ha utilizado para tratar infecciones por hongos. Se ha utilizado tópicamente (en la piel) como crema para tratar infecciones de la piel, y como crema o supositorio (insertado en la vagina) para tratar infecciones vaginales. Algunas marcas de clotrimazol incluyen Femcare®, Lotrimin®, and Mycelex®.</p><p>A veces, cuando las personas se enteran de que están embarazadas, piensan en cambiar la forma de tomar sus medicamentos o dejar de tomarlos por completo. Sin embargo, es importante hablar con sus proveedores de atención de salud antes de realizar cambios en la forma en que toma su medicamento. Sus proveedores de atención de salud pueden hablar con usted sobre los beneficios de tratar su afección y los riesgos de enfermedad no tratada durante el embarazo.</p></blockquote><p>
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<b>
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<i>¿Qué debo hacer si creo que tengo una infección vaginal por hongos durante el embarazo?</i>
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</b>
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</p><blockquote><p>Las personas son más propensas a contraer infecciones por hongos durante el embarazo que en otros momentos. Si cree que tiene una infección vaginal por hongos, es importante consultar a su proveedor de atención de salud para asegurarse de que la infección sea por hongos antes de intentar tratarla por su cuenta. Si tiene otro tipo de infección, es posible que necesite un tratamiento diferente.</p></blockquote><p>
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<b>
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<i>Uso clotrimazol. ¿Puede hacer que me resulte más difícil quedar embarazada?</i>
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</b>
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</p><blockquote><p>No se espera que el uso de clotrimazol dificulte el embarazo.</p></blockquote><p>
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<b>
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<i>¿Usar clotrimazol aumenta la probabilidad de aborto espontáneo?</i>
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</b>
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</p><blockquote><p>El aborto espontáneo es común y puede ocurrir en cualquier embarazo por muchas razones diferentes. Un estudio encontró un pequeño aumento en la probabilidad de aborto espontáneo con el uso de clotrimazol, pero hubo varios problemas con este estudio que podrían haber afectado los resultados. Otros estudios no han encontrado que el clotrimazol aumente la probabilidad de aborto espontáneo.</p></blockquote><p>
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<b>
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<i>¿Usar clotrimazol aumenta la probabilidad de defectos de nacimiento?</i>
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</b>
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</p><blockquote><p>Cada embarazo comienza con un 3-5% de probabilidad de tener un defecto de nacimiento. Esto se conoce como riesgo de fondo. Los medicamentos tópicos o vaginales ingresan al cuerpo en cantidades más bajas que los medicamentos orales (pastillas). Esto significa que llega menos medicamento al feto en desarrollo. Dado que el clotrimazol tópico y vaginal no se absorbe bien, es poco probable que aumente los riesgos de embarazo. La mayoría de los estudios han demostrado que el clotrimazol en dosis bajas (<400 mg/día) no aumenta la probabilidad de defectos de nacimiento.</p></blockquote><p>
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<b>
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<i>¿Usar clotrimazol durante el embarazo aumenta la probabilidad de otros problemas relacionados con el embarazo?</i>
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</b>
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</p><blockquote><p>No se han realizado estudios para ver el clotrimazol aumenta la probabilidad de problemas relacionados con el embarazo, como parto prematuro (parto antes de la semana 37) o bajo peso al nacer (que pesa menos de 5 libras, 8 onzas [2500 gramos] al nacer).</p></blockquote><p>
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<b>
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<i>¿Usar clotrimazol durante el embarazo afecta el comportamiento o aprendizaje futuro para el niño?</i>
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</b>
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</p><blockquote><p>No se han realizado estudios para ver si el clotrimazol puede causar problemas de comportamiento o aprendizaje en el niño.</p><p>
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<b>La lactancia mientras usar <i>clotrimazol</i>:</b>
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</p><p>No hay estudios que analicen el uso de clotrimazol durante la lactancia. Sin embargo, debido a que solo se espera que pequeñas cantidades del medicamento pasen a la leche materna cuando el clotrimazol se usa tópicamente, no se espera que cause efectos secundarios en un niño lactante. En forma de píldora, el clotrimazol se ha administrado directamente a los bebés bajo el cuidado de un proveedor de atención de salud para tratar las infecciones por hongos. Si se usa en los pezones, cualquier exceso de crema o ungüento debe eliminarse de los pezones antes de amamantar. Asegúrese de hablar con su proveedor de atención de salud acerca de todas sus preguntas sobre la lactancia.</p></blockquote><p>
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<b>
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<i>Si un hombre usa clotrimazol, ¿podría afectar la fertilidad o aumentar la probabilidad de defectos de nacimiento?</i>
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</b>
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</p><blockquote><p>No se han realizado estudios para ver si el clotrimazol podría afectar la fertilidad masculina (capacidad de embarazar a la pareja) o aumentar la probabilidad de defectos de nacimiento por encima del riesgo de fondo. En general, es poco probable que las exposiciones que tienen los padres o donantes de esperma aumenten los riesgos de un embarazo. Para más información, consulte la hoja informativa de MotherToBaby acerca de Exposiciones Paternas en <a href="https://mothertobaby.org/es/hojas-informativas/exposiciones-paternas/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://mothertobaby.org/es/hojas-informativas/exposiciones-paternas/</a>.</p></blockquote></div><div id="R001"><h2 id="_R001_">Referencias Seleccionadas:</h2><ul class="simple-list"><li class="half_rhythm"><div class="bk_ref" id="c042">Butler
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DC, et al. 2014. Safety of dermatologic medications in pregnancy and lactation: Part II. Lactation. J Am Acad Dermatol, 70(3):417
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e1-10. [<a href="https://pubmed.ncbi.nlm.nih.gov/24528912" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24528912</span></a>]</div></li><li class="half_rhythm"><div class="bk_ref" id="c043">Carter
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TC, et al. 2008. Antifungal drugs and the risk of selected birth defects.
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Am J Obstet Gyn, 198:191-193. [<a href="https://pubmed.ncbi.nlm.nih.gov/18226621" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18226621</span></a>]</div></li><li class="half_rhythm"><div class="bk_ref" id="c044">Daniel
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S, et al. 2018. Vaginal antimycotics and the risk for spontaneous abortions.
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Am J Obstet Gynecol,
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218(6):601.e1-601.e7. [<a href="https://pubmed.ncbi.nlm.nih.gov/29510088" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29510088</span></a>]</div></li><li class="half_rhythm"><div class="bk_ref" id="c045">Giavini
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E, Menegola
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E.
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2010. Are azole fungicides a teratogenic risk for human conceptus?
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Toxicol Lett,
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198(2):106-111. [<a href="https://pubmed.ncbi.nlm.nih.gov/20633616" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20633616</span></a>]</div></li><li class="half_rhythm"><div class="bk_ref" id="c046">Mendling
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W, Brasch
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J. 2012. Guidelines vulvovaginal candidosis (2010) of the German Society for Gynecology and Obstetrics, the Working Group for Infections and Infectimmunology in Gynecology and Obstetrics, the German Society of Dermatology, the Board of German Dermatologists and German speaking Mycological Society.
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Mycoses, Jul (55) Suppl
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3:1-13. [<a href="https://pubmed.ncbi.nlm.nih.gov/22519657" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22519657</span></a>]</div></li><li class="half_rhythm"><div class="bk_ref" id="c047">Murase
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JE, et al. 2014. Safety of dermatologic medications in pregnancy and lactation: Part 1 Pregnancy.
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J Am Acad Dermatol,
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70(3):401.e1-14. [<a href="https://pubmed.ncbi.nlm.nih.gov/24528911" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24528911</span></a>]</div></li><li class="half_rhythm"><div class="bk_ref" id="c048">Rotem
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R, et al. 2018. Risk of major congenital malformations following first-trimester exposure to vaginal azoles used for treating vulvovaginal candidiasis: a population-based retrospective cohort study.
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BJOG,
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125(12):1550-1556. [<a href="https://pubmed.ncbi.nlm.nih.gov/29790255" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29790255</span></a>]</div></li></ul></div></div></div>
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<div xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Views</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="PDF_download" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li><a href="/books/NBK605064/?report=reader">PubReader</a></li><li><a href="/books/NBK605064/?report=printable">Print View</a></li><li><a data-jig="ncbidialog" href="#_ncbi_dlg_citbx_NBK605064" data-jigconfig="width:400,modal:true">Cite this Page</a><div id="_ncbi_dlg_citbx_NBK605064" style="display:none" title="Cite this Page"><div class="bk_tt">Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Clotrimazol. 2023 Oct.<span class="bk_cite_avail"></span></div></div></li><li><a href="/books/NBK605064/pdf/Bookshelf_NBK605064.pdf">PDF version of this page</a> (116K)</li></ul></div></div><div class="portlet"><div class="portlet_head"><div class="portlet_title"><h3><span>Link to English version of this Fact Sheet</span></h3></div><a name="Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="document-links" id="Shutter"></a></div><div class="portlet_content"><ul xmlns:np="http://ncbi.gov/portal/XSLT/namespace" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="simple-list"><li>
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<a href="/books/n/mtb/clotrimazole-en/">Clotrimazole</a>
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