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<meta name="robots" content="INDEX,FOLLOW,NOARCHIVE" /><meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed®) [Internet]" /><meta name="citation_title" content="Quizartinib" /><meta name="citation_publisher" content="National Institute of Child Health and Human Development" /><meta name="citation_date" content="2023/11/15" /><meta name="citation_pmid" content="38051808" /><meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK597798/" /><meta name="citation_keywords" content="Quizartinib" /><meta name="citation_keywords" content="Vanflyta" /><meta name="citation_keywords" content="AC220" /><meta name="citation_keywords" content="AC-220" /><meta name="citation_keywords" content="AC 220" /><meta name="citation_keywords" content="AC010220" /><meta name="citation_keywords" content="CHEBI:90217AC-010220" /><meta name="citation_keywords" content="1132827-21-4 (HCl)" /><meta name="citation_keywords" content="AC 010220" /><meta name="citation_keywords" content="ASP-2689" /><meta name="citation_keywords" content="7LA4O6Q0D3" /><meta name="citation_keywords" content="CHEMBL576982" /><meta name="citation_keywords" content="N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Quizartinib" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="National Institute of Child Health and Human Development" /><meta name="DC.Date" content="2023/11/15" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK597798/" /><meta name="description" content="No information is available on the clinical use of quizartinib during breastfeeding. Because quizartinib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, the manufacturer recommends that breastfeeding be discontinued during quizartinib therapy and for 1 month after the last dose." /><meta name="og:title" content="Quizartinib" /><meta name="og:type" content="book" /><meta name="og:description" content="No information is available on the clinical use of quizartinib during breastfeeding. Because quizartinib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, the manufacturer recommends that breastfeeding be discontinued during quizartinib therapy and for 1 month after the last dose." /><meta name="og:url" content="https://www.ncbi.nlm.nih.gov/books/NBK597798/" /><meta name="og:site_name" content="NCBI Bookshelf" /><meta name="og:image" content="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-lactmed-lrg.png" /><meta name="twitter:card" content="summary" /><meta name="twitter:site" content="@ncbibooks" /><meta name="bk-non-canon-loc" content="/books/n/lactmed/quizartinib/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK597798/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" /><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript">window.name="mainwindow";</script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script>
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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. </p></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK597798_"><span class="title" itemprop="name">Quizartinib</span></h1><p class="small">Last Revision: <span itemprop="dateModified">November 15, 2023</span>.</p></div><div class="body-content whole_rhythm" itemprop="text"><p>CASRN: 950769-58-1</p><a href="https://pubchem.ncbi.nlm.nih.gov/substance/391904425" title="View this structure in PubChem" class="img_link" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubchem"><img src="https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&sid=391904425" alt="image 391904425 in the ncbi pubchem database" /></a><div id="quizartinib.Drug_Levels_and_Effects"><h2 id="_quizartinib_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="quizartinib.Summary_of_Use_during_Lactat"><h3>Summary of Use during Lactation</h3><p>No information is available on the clinical use of quizartinib during breastfeeding. Because quizartinib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, the manufacturer recommends that breastfeeding be discontinued during quizartinib therapy and for 1 month after the last dose.</p></div><div id="quizartinib.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> Relevant published information was not found as of the revision date.</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="quizartinib.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="quizartinib.Effects_on_Lactation_and_Bre"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div></div><div id="quizartinib.Substance_Identification"><h2 id="_quizartinib_Substance_Identification_">Substance Identification</h2><div id="quizartinib.Substance_Name"><h3>Substance Name</h3><p>Quizartinib</p></div><div id="quizartinib.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>950769-58-1</p></div><div id="quizartinib.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Antineoplastic Agents</p><p>Enzyme Inhibitors</p><p>Protein Kinase Inhibitors</p><p>Signal Transduction Inhibitors</p></div></div><div><dl class="temp-labeled-list small"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></div><div id="bk_toc_contnr"></div></div></div>
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