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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/Book"><div class="meta-content fm-sec"><div class="iconblock whole_rhythm clearfix no_top_margin"><a href="https://ouhsc.edu/" title="University of Oklahoma Health Sciences Center" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-spyogenes2-lrg.png" alt="Cover of Streptococcus pyogenes: Basic Biology to Clinical Manifestations" /></a><div class="icnblk_cntnt"><h1 id="_NBK587111_"><span itemprop="name">Streptococcus pyogenes: Basic Biology to Clinical Manifestations</span>, <span itemprop="bookEdition">2nd</span> edition</h1><p class="contrib-group"><h4>Editors</h4>Editors: <span itemprop="editor">Joseph J. Ferretti</span>, PhD,<sup>1</sup> <span itemprop="editor">Dennis L. Stevens</span>, PhD,<sup>2</sup> and <span itemprop="editor">Vincent A. Fischetti</span>, PhD<sup>3</sup>.</p><h4>Affiliations</h4><div class="affiliation"><sup>1</sup> Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA<div><span class="email-label">Email: </span><a href="mailto:dev@null" data-email="ude.cshuo@itterreF-hpesoJ" class="oemail">ude.cshuo@itterreF-hpesoJ</a></div></div><div class="affiliation"><sup>2</sup> VA Medical Center, Boise, ID</div><div class="affiliation"><sup>3</sup> The Rockefeller University, New York, NY</div><div class="half_rhythm">Oklahoma City (OK): <a href="https://ouhsc.edu/" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">University of Oklahoma Health Sciences Center</span></a>; <span itemprop="datePublished">2022 Oct 8</span>.</div><div>© The University of Oklahoma Health Sciences Center.</div></div></div></div><div class="body-content whole_rhythm" itemprop="text"><div><h2>Contents</h2><ul id="toc_tllNBK587111_toc_preface" class="simple-list toc"><li class="half_rhythm" id="toc_itm_NBK587111_toc_preface"><a class="toc-item" href="/books/n/spyogenes2/preface/">Preface</a><div>Joseph Ferretti, Dennis Stevens, and Vincent Fischetti.</div><div class="small">Created: June 2, 2022; Last Update: December 1, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_introduction"><a class="toc-item" href="/books/n/spyogenes2/introduction/">1. History of <i>Streptococcus pyogenes</i> Research</a><div>Joseph J. Ferretti.</div><div class="small">Created: May 31, 2022; Last Update: November 19, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_mprotein"><a class="toc-item" href="/books/n/spyogenes2/mprotein/">2. M Protein and Other Surface Proteins on <i>Streptococcus pyogenes</i></a><div>Vincent A. Fischetti.</div><div class="small">Created: June 1, 2022; Last Update: November 30, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_pili"><a class="toc-item" href="/books/n/spyogenes2/pili/">3. <i>Streptococcus pyogenes</i> pili</a><div>Immaculada Margarit.</div><div class="small">Created: June 2, 2022; Last Update: October 5, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_capsule"><a class="toc-item" href="/books/n/spyogenes2/capsule/">4. Cell Wall and Surface Molecules of <i>Streptococcus pyogenes</i>: Capsule</a><div>Michael R. Wessels.</div><div class="small">Created: June 4, 2022; Last Update: November 30, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_spatialreg"><a class="toc-item" href="/books/n/spyogenes2/spatialreg/">5. The spatial regulation of protein sorting in <i>Streptococcus pyogenes</i></a><div>Assaf Raz and Vincent A. Fischetti.</div><div class="small">Created: July 17, 2022; Last Update: September 3, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_serotyping"><a class="toc-item" href="/books/n/spyogenes2/serotyping/">6. Molecular Basis of Serotyping and the Underlying Genetic Organization of <i>Streptococcus pyogenes</i></a><div>Debra E. Bessen, Bernard W. Beall, and Mark R. Davies.</div><div class="small">Created: July 19, 2022; Last Update: August 1, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_metabolism"><a class="toc-item" href="/books/n/spyogenes2/metabolism/">7. <i>Streptococcus pyogenes</i> Metabolism</a><div>Vijay Pancholi and Michael Caparon.</div><div class="small">Created: July 20, 2022; Last Update: July 24, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_genomics"><a class="toc-item" href="/books/n/spyogenes2/genomics/">8. Streptococcus <i>pyogenes</i> Genomics</a><div>Norihiko Takemoto, Kohei Ogura, Shinya Watanabe, and Fumito Maruyama.</div><div class="small">Created: May 24, 2022; Last Update: November 30, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_bacteriophages"><a class="toc-item" href="/books/n/spyogenes2/bacteriophages/">9. The Bacteriophages of <i>Streptococcus pyogenes</i></a><div>W. Michael McShan and Scott V. Nguyen.</div><div class="small">Created: July 20, 2022; Last Update: November 19, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_crispr"><a class="toc-item" href="/books/n/spyogenes2/crispr/">10. The CRISPR-Cas system of <i>Streptococcus pyogenes</i>: function and applications</a><div>Andrew Varble and Luciano Marraffini.</div><div class="small">Created: July 20, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_proteome"><a class="toc-item" href="/books/n/spyogenes2/proteome/">11. The <i>Streptococcus pyogenes</i> Proteome</a><div>Eduardo A. Callegari and Michael S. Chaussee.</div><div class="small">Created: July 22, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_transcriptionalregs"><a class="toc-item" href="/books/n/spyogenes2/transcriptionalregs/">12. Virulence-Related Transcriptional Regulators of <i>Streptococcus pyogenes</i></a><div>Luis A. Vega, Horst Malke, and Kevin S. McIver.</div><div class="small">Created: July 24, 2022; Last Update: October 7, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_virulence"><a class="toc-item" href="/books/n/spyogenes2/virulence/">13. Secreted Virulence Factors of <i>Streptococcus pyogenes</i></a><div>Timothy Barnett, Anuk Indraratna, and Martina Sanderson-Smith.</div><div class="small">Created: July 28, 2022; Last Update: November 19, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_superantigens"><a class="toc-item" href="/books/n/spyogenes2/superantigens/">14. <i>Streptococcus pyogenes</i> Superantigens: Biological properties and potential role in disease</a><div>Thomas Proft and John D. Fraser.</div><div class="small">Created: May 24, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_biofilm"><a class="toc-item" href="/books/n/spyogenes2/biofilm/">15. <i>Streptococcus pyogenes</i> Biofilm</a><div>Christie Young, Robert C. Holder, Lily Dubois, and Sean D., Reid.</div><div class="small">Created: August 21, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_adherence"><a class="toc-item" href="/books/n/spyogenes2/adherence/">16. <i>Streptococcus pyogenes</i> Adherence</a><div>Patricia A. Ryan and Chad W. Euler.</div><div class="small">Created: August 24, 2022; Last Update: November 19, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_adhesion"><a class="toc-item" href="/books/n/spyogenes2/adhesion/">17. Adhesion and invasion of <i>Streptococcus pyogenes</i> into host cells and clinical relevance of intracellular streptococci</a><div>Manfred Rohde and P. Patrick Cleary.</div><div class="small">Created: September 4, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_carrier"><a class="toc-item" href="/books/n/spyogenes2/carrier/">18. The Carrier State of <i>Streptococcus pyogenes</i></a><div>Judith Martin.</div><div class="small">Created: September 5, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_epidemiology"><a class="toc-item" href="/books/n/spyogenes2/epidemiology/">19. Epidemiology of <i>Streptococcus pyogenes</i></a><div>Androulla Efstratiou and Theresa Lamagni.</div><div class="small">Created: October 30, 2022; Last Update: November 7, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_animal"><a class="toc-item" href="/books/n/spyogenes2/animal/">20. Animal Models of <i>Streptococcus pyogenes</i> Infection</a><div>Michael E. Watson, Jr., Melody N. Neely, and Michael G. Caparon.</div><div class="small">Created: September 5, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_burden"><a class="toc-item" href="/books/n/spyogenes2/burden/">21. Global Disease Burden of <i>Streptococcus pyogenes</i></a><div>Natalie Craik, Thel Hla, Jeffery Cannon, Hannah Moore, Jonathan R. Carapetis, and Amy Sanyahumbi.</div><div class="small">Created: August 21, 2022; Last Update: August 27, 2024.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_pharyngitis"><a class="toc-item" href="/books/n/spyogenes2/pharyngitis/">22. <i>Streptococcus pyogenes</i> Pharyngitis and Scarlet Fever</a><div>Michael R. Wessels.</div><div class="small">Created: September 5, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_impetigo"><a class="toc-item" href="/books/n/spyogenes2/impetigo/">23. <i>Streptococcus pyogenes</i> Impetigo, Erysipelas, and Cellulitis</a><div>Dennis L. Stevens and Amy E. Bryant.</div><div class="small">Created: September 7, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_groupa"><a class="toc-item" href="/books/n/spyogenes2/groupa/">24. Severe <i>Streptococcus pyogenes</i> Infections</a><div>Dennis L. Stevens and Amy E. Bryant.</div><div class="small">Created: September 7, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_rheumaticfever"><a class="toc-item" href="/books/n/spyogenes2/rheumaticfever/">25. Acute Rheumatic Fever and Rheumatic Heart Disease</a><div>Scott Wirth, Dianne Sika-Paotonu, Andrea Beaton, Aparna Raghu, Andrew Steer, and Jonathan Carapetis.</div><div class="small">Created: June 19, 2024; Last Update: July 4, 2024.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_pandas"><a class="toc-item" href="/books/n/spyogenes2/pandas/">26. Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)</a><div>Susan Swedo, Chandra M. Menendez, and Madeleine W. Cunningham.</div><div class="small">Created: July 7, 2024; Last Update: September 13, 2024.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_glomer"><a class="toc-item" href="/books/n/spyogenes2/glomer/">27. Post-<i>Streptococcus pyogenes</i> Glomerulonephritis</a><div>Bernardo Rodriguez-Iturbe and Mark Haas.</div><div class="small">Created: September 9, 2022; Last Update: October 4, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_sequelae"><a class="toc-item" href="/books/n/spyogenes2/sequelae/">28. Post-Streptococcal Autoimmune Sequelae, Rheumatic Fever and Beyond: A New Perspective</a><div>Madeleine W. Cunningham and Christine A. Kirvan.</div><div class="small">Created: March 12, 2024.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_diagnosis"><a class="toc-item" href="/books/n/spyogenes2/diagnosis/">29. Laboratory Diagnosis of <i>Streptococcus pyogenes</i> (group A streptococci)</a><div>Barbara Spellerberg and Claudia Brandt.</div><div class="small">Created: September 15, 2022; Last Update: October 9, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_resistance"><a class="toc-item" href="/books/n/spyogenes2/resistance/">30. Mechanisms of <i>Streptococcus pyogenes</i> Antibiotic Resistance</a><div>Vincent Cattoir.</div><div class="small">Created: September 19, 2022; Last Update: October 9, 2022.</div></li><li class="half_rhythm" id="toc_itm_NBK587111_toc_vaccine"><a class="toc-item" href="/books/n/spyogenes2/vaccine/">31. Current Approaches to Vaccine Development of <i>Streptococcus pyogenes</i></a><div>Nichaela Harbison-Price, Tania Rivera-Hernandez, Joshua Osowicki, Mark R. Davies, Andrew C. Steer, Mark J. Walker, and James B. Dale.</div><div class="small">Created: May 29, 2022; Last Update: October 9, 2022.</div></li></ul></div></div></div>
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