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stroke-linecap="round" style="fill:#FFF" d="m320,350a153,153 0 1,0-2,2l170,170m-91-117 110,110-26,26-110-110"></path></svg></a><a id="jr-fip-done" class="wsprkl btn" title="Dismiss find">✘</a></nav><nav id="jr-fip-info-p"><a id="jr-fip-prev" class="wsprkl btn" title="Jump to previuos match">◀</a><button id="jr-fip-matches">no matches yet</button><a id="jr-fip-next" class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style"><div class="fm-sec bkr_bottom_sep"><div class="bkr_thumb"><a href="https://www.nice.org.uk" title="National Institute for Health and Care Excellence (NICE)" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-niceng157er13-lrg.png" alt="Cover of Evidence review for hip replacement approach" /></a></div><div class="bkr_bib"><h1 id="_NBK561418_"><span itemprop="name">Evidence review for hip replacement approach</span></h1><div class="subtitle">Joint replacement (primary): hip, knee and shoulder</div><p><b>Evidence review M</b></p><p><i>NICE Guideline, No. 157</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">National Guideline Centre (UK)</span>.</p><div class="half_rhythm">London: <a href="https://www.nice.org.uk" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">National Institute for Health and Care Excellence (NICE)</span></a>; <span itemprop="datePublished">2020 Jun</span>.<div class="small">ISBN-13: <span itemprop="isbn">978-1-4731-3722-6</span></div></div><div><a href="/books/about/copyright/">Copyright</a> © NICE 2020.</div></div><div class="bkr_clear"></div></div><div id="niceng157er13.s1"><h2 id="_niceng157er13_s1_">1. Hip replacement approach</h2><div id="niceng157er13.s1.1"><h3>1.1. Review question: In adults having primary elective hip replacement, what is the most clinical and cost-effective approach: posterior, direct anterior, anterolateral, direct superior or SuperPATH?</h3></div><div id="niceng157er13.s1.2"><h3>1.2. Introduction</h3><p>There are a number of different surgical ways (approaches) to access the hip joint. Over the last decade total hip replacements have been performed using 2 main approaches: The posterior approach in which the hip joint is approached from the back by releasing and reflecting the short external rotators and dividing the capsule at the back of the hip; and the anterolateral (Hardinge) approach in which the hip joint is approached from the side by releasing a portion of the hip abductors and dividing the underlying hip capsule. Neither of these approaches follow a true internervous plane and both are thought to have advantages and disadvantages with respect to complications such as dislocation, nerve injury and post-operative limp.</p><p>There is increasing interest in alternatives to these two approaches such as the direct anterior, direct superior and super path (supercapsular percutaneously assisted). These approaches are attractive as they either use a true internervous plane or are reported to minimise soft tissue damage around the hip, both of which should theoretically improve recovery times and reduce length of hospital stay. This review aims to assess the clinical and cost effectiveness of all the approaches including the main approaches and newer approaches.</p></div><div id="niceng157er13.s1.3"><h3>1.3. PICO table</h3><p>For full details see the review protocol in <a href="#niceng157er13.appa">Appendix A</a>:
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<div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab1"><a href="/books/NBK561418/table/niceng157er13.tab1/?report=objectonly" target="object" title="Table 1" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab1" rid-ob="figobniceng157er13tab1"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab1/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab1/?report=previmg" alt="Table 1. PICO characteristics of review question." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab1"><a href="/books/NBK561418/table/niceng157er13.tab1/?report=objectonly" target="object" rid-ob="figobniceng157er13tab1">Table 1</a></h4><p class="float-caption no_bottom_margin">PICO characteristics of review question. </p></div></div></p></div><div id="niceng157er13.s1.4"><h3>1.4. Clinical evidence</h3><div id="niceng157er13.s1.4.1"><h4>1.4.1. Included studies</h4><p>A search was conducted for randomised controlled trials comparing the effectiveness of different surgical hip replacement approaches utilised for knee joint replacement surgery. Twenty six RCTs were included in the review;<a class="bibr" href="#niceng157er13.ref2" rid="niceng157er13.ref2"><sup>2</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref3" rid="niceng157er13.ref3"><sup>3</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref9" rid="niceng157er13.ref9"><sup>9</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref10" rid="niceng157er13.ref10"><sup>10</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref12" rid="niceng157er13.ref12"><sup>12</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref13" rid="niceng157er13.ref13"><sup>13</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref15" rid="niceng157er13.ref15"><sup>15</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref16" rid="niceng157er13.ref16"><sup>16</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref41" rid="niceng157er13.ref41"><sup>41</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref52" rid="niceng157er13.ref52"><sup>52</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref56" rid="niceng157er13.ref56"><sup>56</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref59" rid="niceng157er13.ref59"><sup>59</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref64" rid="niceng157er13.ref64"><sup>64</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref74" rid="niceng157er13.ref74"><sup>74</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref81" rid="niceng157er13.ref81"><sup>81</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref87" rid="niceng157er13.ref87"><sup>87</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref88" rid="niceng157er13.ref88"><sup>88</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref90" rid="niceng157er13.ref90"><sup>90</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref95" rid="niceng157er13.ref95"><sup>95</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref97" rid="niceng157er13.ref97"><sup>97</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref108" rid="niceng157er13.ref108"><sup>108</sup></a><sup>–</sup><a class="bibr" href="#niceng157er13.ref110" rid="niceng157er13.ref110"><sup>110</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref115" rid="niceng157er13.ref115"><sup>115</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref118" rid="niceng157er13.ref118"><sup>118</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref124" rid="niceng157er13.ref124"><sup>124</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref128" rid="niceng157er13.ref128"><sup>128</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref130" rid="niceng157er13.ref130"><sup>130</sup></a> these are summarised in <a class="figpopup" href="/books/NBK561418/table/niceng157er13.tab2/?report=objectonly" target="object" rid-figpopup="figniceng157er13tab2" rid-ob="figobniceng157er13tab2">Table 2</a> below.</p><p>Studies covering four comparisons were found. These were:</p><p>Direct anterior approach compared to anterolateral approach – <b>10</b> RCTs</p><p>Direct anterior approach versus posterior approach – <b>8</b> RCTs</p><p>Posterior approach versus anterolateral approach – <b>7</b> RCTs</p><p>SuperPATH approach versus posterior approach – <b>1</b> RCT</p><p>Evidence from these studies is summarised in the clinical evidence summary below (<a class="figpopup" href="/books/NBK561418/table/niceng157er13.tab3/?report=objectonly" target="object" rid-figpopup="figniceng157er13tab3" rid-ob="figobniceng157er13tab3">Table 3</a>).</p><p>See also the study selection flow chart in <a href="#niceng157er13.appc">Appendix C</a>: study evidence tables in <a href="#niceng157er13.appd">Appendix D</a>: forest plots in <a href="#niceng157er13.appe">Appendix E</a>: and GRADE tables in <a href="#niceng157er13.apph">Appendix H</a>:</p></div><div id="niceng157er13.s1.4.2"><h4>1.4.2. Excluded studies</h4><p>See the excluded studies list in <a href="#niceng157er13.appi">Appendix I</a>:</p></div><div id="niceng157er13.s1.4.3"><h4>1.4.3. Summary of clinical studies included in the evidence review</h4><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab2"><a href="/books/NBK561418/table/niceng157er13.tab2/?report=objectonly" target="object" title="Table 2" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab2" rid-ob="figobniceng157er13tab2"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab2/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab2/?report=previmg" alt="Table 2. Summary of studies included in the evidence review." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab2"><a href="/books/NBK561418/table/niceng157er13.tab2/?report=objectonly" target="object" rid-ob="figobniceng157er13tab2">Table 2</a></h4><p class="float-caption no_bottom_margin">Summary of studies included in the evidence review. </p></div></div><p>See <a href="#niceng157er13.appd">Appendix D</a>: for full evidence tables.</p></div><div id="niceng157er13.s1.4.4"><h4>1.4.4. Quality assessment of clinical studies included in the evidence review</h4><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab3"><a href="/books/NBK561418/table/niceng157er13.tab3/?report=objectonly" target="object" title="Table 3" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab3" rid-ob="figobniceng157er13tab3"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab3/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab3/?report=previmg" alt="Table 3. Clinical evidence summary: Direct anterior approach versus anterolateral approach." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab3"><a href="/books/NBK561418/table/niceng157er13.tab3/?report=objectonly" target="object" rid-ob="figobniceng157er13tab3">Table 3</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: Direct anterior approach versus anterolateral approach. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab4"><a href="/books/NBK561418/table/niceng157er13.tab4/?report=objectonly" target="object" title="Table 4" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab4" rid-ob="figobniceng157er13tab4"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab4/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab4/?report=previmg" alt="Table 4. Clinical evidence summary: Direct anterior approach versus posterior approach." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab4"><a href="/books/NBK561418/table/niceng157er13.tab4/?report=objectonly" target="object" rid-ob="figobniceng157er13tab4">Table 4</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: Direct anterior approach versus posterior approach. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab5"><a href="/books/NBK561418/table/niceng157er13.tab5/?report=objectonly" target="object" title="Table 5" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab5" rid-ob="figobniceng157er13tab5"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab5/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab5/?report=previmg" alt="Table 5. Clinical evidence summary: Posterior approach versus anterolateral approach." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab5"><a href="/books/NBK561418/table/niceng157er13.tab5/?report=objectonly" target="object" rid-ob="figobniceng157er13tab5">Table 5</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: Posterior approach versus anterolateral approach. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab6"><a href="/books/NBK561418/table/niceng157er13.tab6/?report=objectonly" target="object" title="Table 6" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab6" rid-ob="figobniceng157er13tab6"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab6/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab6/?report=previmg" alt="Table 6. Clinical evidence summary: SuperPATH approach versus posterior approach." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab6"><a href="/books/NBK561418/table/niceng157er13.tab6/?report=objectonly" target="object" rid-ob="figobniceng157er13tab6">Table 6</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: SuperPATH approach versus posterior approach. </p></div></div><p>See <a href="#niceng157er13.appf">Appendix F</a>: for full GRADE tables.</p></div></div><div id="niceng157er13.s1.5"><h3>1.5. Economic evidence</h3><div id="niceng157er13.s1.5.1"><h4>1.5.1. Included studies</h4><p>Two health economic studies were identified with the relevant comparison and have been included in this review.<a class="bibr" href="#niceng157er13.ref82" rid="niceng157er13.ref82"><sup>82</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref102" rid="niceng157er13.ref102"><sup>102</sup></a> The studies are summarised in the health economic evidence profile below (<a class="figpopup" href="/books/NBK561418/table/niceng157er13.tab7/?report=objectonly" target="object" rid-figpopup="figniceng157er13tab7" rid-ob="figobniceng157er13tab7">Table 7</a>) and the health economic evidence table in <a href="#niceng157er13.apph">Appendix H</a>:</p></div><div id="niceng157er13.s1.5.2"><h4>1.5.2. Excluded studies</h4><p>Two studies relating to this review question were identified but were excluded due to limited applicability.<a class="bibr" href="#niceng157er13.ref14" rid="niceng157er13.ref14"><sup>14</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref18" rid="niceng157er13.ref18"><sup>18</sup></a> Two studies relating to this review question were identified but were excluded due to very serious limitations.<a class="bibr" href="#niceng157er13.ref28" rid="niceng157er13.ref28"><sup>28</sup></a><sup>,</sup><a class="bibr" href="#niceng157er13.ref54" rid="niceng157er13.ref54"><sup>54</sup></a> The studies are listed in <a href="#niceng157er13.appi">Appendix I</a>: with reasons for exclusion.</p><p>See also the health economic study selection flow chart in <a href="#niceng157er13.appg">Appendix G</a>:</p></div><div id="niceng157er13.s1.5.3"><h4>1.5.3. Summary of studies included in the economic evidence review</h4><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab7"><a href="/books/NBK561418/table/niceng157er13.tab7/?report=objectonly" target="object" title="Table 7" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab7" rid-ob="figobniceng157er13tab7"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab7/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab7/?report=previmg" alt="Table 7. Health economic evidence profile: Anterior THR versus posterior THR versus lateral THR." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab7"><a href="/books/NBK561418/table/niceng157er13.tab7/?report=objectonly" target="object" rid-ob="figobniceng157er13tab7">Table 7</a></h4><p class="float-caption no_bottom_margin">Health economic evidence profile: Anterior THR versus posterior THR versus lateral THR. </p></div></div></div><div id="niceng157er13.s1.5.4"><h4>1.5.4. Unit costs</h4><p>Relevant unit costs are provided below to aid consideration of cost effectiveness.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13tab8"><a href="/books/NBK561418/table/niceng157er13.tab8/?report=objectonly" target="object" title="Table 8" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13tab8" rid-ob="figobniceng157er13tab8"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.tab8/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.tab8/?report=previmg" alt="Table 8. Weighted average unit costs for HRG HN12 (Elective Very Major Hip Procedures for Non-Trauma) including excess bed days." /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.tab8"><a href="/books/NBK561418/table/niceng157er13.tab8/?report=objectonly" target="object" rid-ob="figobniceng157er13tab8">Table 8</a></h4><p class="float-caption no_bottom_margin">Weighted average unit costs for HRG HN12 (Elective Very Major Hip Procedures for Non-Trauma) including excess bed days. </p></div></div></div></div><div id="niceng157er13.s1.6"><h3>1.6. Evidence statements</h3><div id="niceng157er13.s1.6.1"><h4>1.6.1. Clinical evidence statements</h4><div id="niceng157er13.s1.6.1.1"><h5>Direct anterior approach versus anterolateral approach</h5><p>Evidence from 10 RCTs was found for this comparison.</p><p>A benefit was found for direct anterior approach in length of stay (n=247, very low quality), deep infection at 6 weeks or earlier (n=70, very low quality), and hyperesthesia at later than 2 years (n=87, very low quality).</p><p>A benefit was found for anterolateral approach in surgery time (n=432, very low quality), lateral femoral cutaneous nerve injury at 6 weeks or earlier (n=70, very low quality) and 3 outcomes at later than 2 years: dislocation (n=235, very low quality), revision (n=87, very low quality), and deep infection (n=87, very low quality).</p><p>No difference between approaches was found for blood loss during surgery (n=169, low quality), 4 quality of life or PROMs outcomes at 6 weeks or earlier (n=138 to226, low to very low quality) and 4 quality of life or PROMs outcomes at later than 6 weeks up to 1 year (n=78 or 325, low or very low quality).</p></div><div id="niceng157er13.s1.6.1.2"><h5>Direct anterior approach versus posterior approach</h5><p>Evidence from 8 RCTs was found for this comparison.</p><p>A benefit was found for direct anterior approach in Harris Hip Score at 6 weeks or earlier (n=87, very low quality), revision later than 6 weeks up to 1 year (n=160, very low quality), and dislocation later than 6 weeks up to 1 year (n=261, very low quality).</p><p>A benefit was found for posterior approach in surgery time (n=354, very low quality), lateral cutaneous nerve of the thigh neuropraxia (n=73, moderate quality), blood loss (n=166, low quality), and deep infection at 6 weeks or earlier (n=46, low quality).</p><p>No difference between approaches was found for length of stay (n=405, low quality) and 5 quality of life or PROMs outcomes at 6 weeks or earlier were (n=73 to160, low to very low quality), quality of life or 9 PROMs outcomes at later than 6 weeks to 1 year (n=73 to308, low to very low quality), and 3 PROMs outcomes at later than 2 years (n=75 to79, low to very low quality).</p></div><div id="niceng157er13.s1.6.1.3"><h5>Direct anterior approach versus posterior approach</h5><p>Evidence from 7 RCTs was found for this comparison.</p><p>A benefit was found for direct anterior approach for surgical blood loss (n=110, moderate quality), reoperation later than 6 weeks up to 1 year (n=68, very low quality), and revision later than 2 years (n=243, very low quality).</p><p>A benefit was found for posterior approach in superficial surgical site infection later than 6 weeks up to 1 year (n= 60, moderate quality).</p><p>No difference between approaches was found for surgery time (n=374, very low quality), Harris Hip Score (n=68, very low quality) or pain (n=22, low quality) later than 6 weeks up to 1 year, and Harris Hip Score (n=196, low quality) or dislocation (n=371, low quality) later than 2 years.</p></div><div id="niceng157er13.s1.6.1.4"><h5>SuperPATH approach versus posterior approach</h5><p>Evidence from 1 RCT was found for this comparison (n=92).</p><p>A clinically important benefit for the SuperPATH approach was found for length of stay (moderate quality) PROMS measured with the Barthel Index and Harris Hip Score at 6 weeks or earlier, dislocation later than 6 weeks up to 1 year and (low to very low quality).</p><p>No outcomes favoured posterior approach over SuperPATH approach.</p><p>No difference between approaches was found for surgery time (low quality) and PROMs measured with the Barthel Index and HHS score at later than 6 weeks up to 1 year and (low to very low quality).</p></div></div><div id="niceng157er13.s1.6.2"><h4>1.6.2. Health economic evidence statements</h4><p>Two cost comparisons found that the anterior THR approach was cost saving compared to both the lateral and posterior approaches. Both studies were assessed as partially applicable with potentially serious limitations.</p></div></div><div id="niceng157er13.s1.7"><h3>1.7. The committee’s discussion of the evidence</h3><div id="niceng157er13.s1.7.1"><h4>1.7.1. Interpreting the evidence</h4><div id="niceng157er13.s1.7.1.1"><h5>1.7.1.1. The outcomes that matter most</h5><p>The critical outcomes were mortality, quality of life, revision rate of joint replacement and Patient Reported Outcome Measures (PROMs) at 6 weeks or earlier (short term) later than 6 weeks up to 1 year (moderate term) or after at least 2 years (long term). The benefits of knee joint replacement operations may not present themselves immediately after surgery; they may take months or years to become apparent. Therefore, multiple time points were necessary to capture this variation in outcomes as rehabilitation occurs.</p><p>The important outcomes were deep and superficial surgical site infection, length of stay, reoperation or dislocation rate, intraoperative complications such as nerve damage and surgery time.</p></div><div id="niceng157er13.s1.7.1.2"><h5>1.7.1.2. The quality of the evidence</h5><p>Twenty six RCTs were included in the review, showing outcomes ranging from very low to moderate quality due to risk of bias, imprecision or inconsistency. The majority of the evidence was very low quality mainly due to lack of allocation concealment and blinding, contributing to a higher risk of bias. There was often imprecision due to confidence intervals crossing default minimal important difference. Inconsistency was present several times due to heterogeneity unexplained by subgroup analysis or the number of zero events varying across arms.</p></div><div id="niceng157er13.s1.7.1.3"><h5>1.7.1.3. Benefits and harms</h5><p>There were four approach comparisons included in this review; direct anterior compared to anterolateral in 10 RCTs, direct anterior compared to posterior in 8 RCTs, posterior compared to anterolateral in 7 RCTs, and SuperPATH compared to posterior in 1 RCT.</p><p>The direct anterior versus anterolateral comparison indicated no clinically important difference in 8 for quality of life or PROMs outcomes across short and moderate time points, and blood loss. A clinically important benefit for anterolateral approach was found for revision at 5 years after surgery, dislocation, deep infection (later than 2 years from surgery), lateral femoral cutaneous nerve injury and surgery time. A clinically important benefit for direct anterior approach was found for deep infection at 6 weeks, hyperesthesia and length of stay. The direct anterior versus posterior comparison indicated no clinically important difference for and length of stay, 5 quality of life or PROMs outcomes at short time points, 9 quality of life or PROMs outcomes moderate time points, and 3 PROMs outcomes at the long time point. However there was a clinically important benefit for direct anterior with 1 PROMs outcome (Harris hip score at 6 weeks) along with revision, and dislocation. There was a clinically important benefit for posterior for deep infection, lateral cutaneous nerve of the thigh neuropraxia, blood loss, and surgery time.</p><p>The posterior versus anterolateral comparison showed no clinically important difference for 2 PROMs (Harris hip score) outcomes at moderate and long term time points, dislocation, surgery time and pain. There was a clinically important benefit of the anterolateral approach for revision at around 3 years, reoperation and blood loss. There was a clinically important benefit for the posterior approach for superficial surgical site infection.</p><p>SuperPATH versus posterior approach found no clinically important difference for 2 PROMs outcomes in the moderate term and also surgery time. The review found a clinically important benefit of the SuperPATH approach for 2 PROMs outcomes in the short term, and also dislocation and length of stay. No clinically important benefits were found for the posterior approach.</p><p>The committee related the evidence from the review to their own knowledge and experiences of the various approaches. The direct anterior appears better in the short term, with the committee noting the these are seen in the first 6 weeks after surgery, but these benefits tend to equalise after for the moderate to long term outcomes. Going home the day after surgery, feeling comfortable and getting back to work quickly are often important factors for patients.</p><p>Lateral cutaneous nerve of the thigh is a very painful adverse event and was found to be associated with the direct anterior approach in 2 comparisons. 1 outcome was nerve injury in the direct anterior versus anterolateral comparison and the other was neuropraxia in the direct anterior versus posterior comparison. The former showed a small increase in the direct anterior group while the latter affected over 80% in the direct anterior group and no people in the posterior group at 12 weeks. This was discussed by the committee and it was considered that such a high number of events may have been caused by the study’s definition of the outcome which was the absence of normal sensation rather than pain or discomfort. The committee were cognisant that this outcome was not associated with lower PROMs in the study as it is conceivable that absence of normal sensation for a limited period of time does not have a significant negative affect on a person’s experience of the post-surgery period.</p><p>There was some evidence at the long time point for 3 of the 4 comparisons. However the committee felt that much longer time horizons of at least 10 years would have given a better view of revision, quality of life, and PROMs outcomes.</p><p>The committee agreed the evidence did not indicate the superiority of any single approach.</p><p>In the NHS the great majority of people undergo hip replacement via the posterior or anterolateral approaches. In 2017 the National Joint Registry showed the breakdown of surgical approach for hip replacement as 72% for the posterior approach, 25% for the anterolateral approach, and 4% for other approaches. The committee agreed that most surgeons can use an anterolateral approach or posterior approach as initial training provides this. However the other approaches are less commonly used and would require training and experience to carry out effectively. tThe committee also agreed that the surgeon undertaking the approach should have experience and competence in that particular approach to get consistently good results.</p><p>The committee were aware that there was very limited RCT data investigating newer approaches. Therefore they agreed to make a consider recommendation for posterior or anterolateral surgical approaches, as they are established approaches and evidence did not show a benefit of one over the other. The also agreed to make a research recommendation to compare SuperPATH approach, direct superior approach, and direct anterior approach to either of the ‘traditional’ posterior or anterolateral approaches.</p></div></div><div id="niceng157er13.s1.7.2"><h4>1.7.2. Cost effectiveness and resource use</h4><p>The economic evidence showed that the anterior approach was cost saving compared to both the lateral and posterior approaches to total hip replacement, despite having the most expensive operating room costs. The net cost savings for the anterior approach were a result of reduced inpatient length of stay after the initial procedure. The quality of the evidence was very low; it was particularly notable that there was no multivariate adjustment, although there was no significant difference in key characteristics, such as BMI. The presented study also had a short follow-up (3 months) which is problematic as it may not have captured the benefits of the posterior and lateral approaches after this time.</p><p>The implant and closure costs between the different approaches will be roughly similar. The similarity in many of the costs and resource use between the approaches is shown through them all mapping to the same HRG code (HN12). However, additional resource use may be associated training surgeons to use the newer anterior approach. Most surgeons will be able to conduct lateral or posterior approaches as these make up the large majority of current practice. The anterior approach is likely to require a longer learning curve and there may be resource implications to this. The clinical review also suggested that the anterior approach may be associated with more neuropraxia at 12 weeks compared to the other approaches, there may be costs associated with treating this adverse event. Given this, the committee made a ‘consider’ recommendation for the lateral and posterior approaches.</p><p>No economic evidence was available for the SuperPath or direct superior approaches. Similarly to the anterior approach, SuperPath and direct superior are newer approaches which have not yet been fully explored in the literature. According the NJR, roughly 1/25 total hip replacements are done by anterior or SuperPath. The committee thought that there was some evidence for the short term benefits of these newer approaches, but evidence was lacking for the long term benefits and costs. Therefore a research recommendation was made addressing this.</p></div></div></div><div id="niceng157er13.rl.r1"><h2 id="_niceng157er13_rl_r1_">References</h2><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="niceng157er13.ref1">Anonymous. Erratum: A prospective randomized controlled trial comparing the efficacy of fascia iliaca compartment block versus local anesthetic infiltration after hip arthroscopic surgery. Arthroscopy - Journal of Arthroscopic and Related Surgery. 2018; 34(1):348 [<a href="https://pubmed.ncbi.nlm.nih.gov/28003068" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28003068</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>2.</dt><dd><div class="bk_ref" id="niceng157er13.ref2">Barrett
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JP. Prospective randomized study of direct anterior vs postero-lateral approach for total hip arthroplasty. Journal of Arthroplasty. 2013; 28(9):1634–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/23523485" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23523485</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>3.</dt><dd><div class="bk_ref" id="niceng157er13.ref3">Barrett
|
|
WP, Turner
|
|
SE, Murphy
|
|
JA, Flener
|
|
JL, Alton
|
|
TB. Prospective, randomized study of direct anterior approach vs posterolateral approach total hip arthroplasty: A concise 5-year follow-up evaluation. Journal of Arthroplasty. 2019; 34(6):1139–1142 [<a href="https://pubmed.ncbi.nlm.nih.gov/30885407" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30885407</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>4.</dt><dd><div class="bk_ref" id="niceng157er13.ref4">Berstock
|
|
JR, Blom
|
|
AW, Beswick
|
|
AD. A systematic review and meta-analysis of the standard versus mini-incision posterior approach to total hip arthroplasty. Journal of Arthroplasty. 2014; 29(10):1970–82 [<a href="https://pubmed.ncbi.nlm.nih.gov/25023783" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25023783</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>5.</dt><dd><div class="bk_ref" id="niceng157er13.ref5">Berstock
|
|
JR, Blom
|
|
AW, Beswick
|
|
AD. A systematic review and meta-analysis of complications following the posterior and lateral surgical approaches to total hip arthroplasty. Annals of the Royal College of Surgeons of England. 2015; 97(1):11–6 [<a href="/pmc/articles/PMC4473890/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4473890</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25519259" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25519259</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>6.</dt><dd><div class="bk_ref" id="niceng157er13.ref6">Bon
|
|
G, Kacem
|
|
EB, Lepretre
|
|
PM, Weissland
|
|
T, Mertl
|
|
P, Dehl
|
|
M
|
|
et al. Does the direct anterior approach allow earlier recovery of walking following total hip arthroplasty? A randomized prospective trial using accelerometry. Orthopaedics & Traumatology, Surgery & Research. 2019; 105(3):445–452 [<a href="https://pubmed.ncbi.nlm.nih.gov/30853454" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30853454</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>7.</dt><dd><div class="bk_ref" id="niceng157er13.ref7">Bostrom
|
|
MP, Demetrakopoulos
|
|
D, Reinhart
|
|
J, Sculco
|
|
TP. Minimally invasive posterior approach to total hip replacement. Current Opinion in Orthopaedics. 2005; 16(1):2–4</div></dd></dl><dl class="bkr_refwrap"><dt>8.</dt><dd><div class="bk_ref" id="niceng157er13.ref8">Botha
|
|
PJ, Gie
|
|
GA, Esler
|
|
CNA. Bilateral total hip arthroplasty: A comparison of two surgical approaches. Journal of Bone and Joint Surgery (British Volume). 1996; 78(Suppl 2-3):102–103</div></dd></dl><dl class="bkr_refwrap"><dt>9.</dt><dd><div class="bk_ref" id="niceng157er13.ref9">Brismar
|
|
BH, Hallert
|
|
O, Tedhamre
|
|
A, Lindgren
|
|
JU. Early gain in pain reduction and hip function, but more complications following the direct anterior minimally invasive approach for total hip arthroplasty: A randomized trial of 100 patients with 5 years of follow up. Acta Orthopaedica. 2018; 89(5):484–489 [<a href="/pmc/articles/PMC6202757/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6202757</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30350758" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30350758</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>10.</dt><dd><div class="bk_ref" id="niceng157er13.ref10">Catma
|
|
FM, Ozturk
|
|
A, Unlu
|
|
S, Ersan
|
|
O, Altay
|
|
M. Posterior hip approach yields better functional results vis-a-vis anterolateral approach in total hip arthroplasty for patients with severe hip dysplasia: A prospective randomized controlled clinical study. Journal of Orthopaedic Surgery. 2017; 25(2):2309499017717179 [<a href="https://pubmed.ncbi.nlm.nih.gov/28659053" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28659053</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>11.</dt><dd><div class="bk_ref" id="niceng157er13.ref11">Cheng
|
|
T, Feng
|
|
JG, Liu
|
|
T, Zhang
|
|
XL. Minimally invasive total hip arthroplasty: A systematic review. International Orthopaedics. 2009; 33(6):1473–81 [<a href="/pmc/articles/PMC2899157/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2899157</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19277652" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19277652</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>12.</dt><dd><div class="bk_ref" id="niceng157er13.ref12">Cheng
|
|
TE, Wallis
|
|
JA, Taylor
|
|
NF, Holden
|
|
CT, Marks
|
|
P, Smith
|
|
CL
|
|
et al. A prospective randomized clinical trial in total hip arthroplasty-comparing early results between the direct anterior approach and the posterior approach. Journal of Arthroplasty. 2017; 32(3):883–890 [<a href="https://pubmed.ncbi.nlm.nih.gov/27687805" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27687805</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>13.</dt><dd><div class="bk_ref" id="niceng157er13.ref13">Christensen
|
|
CP, Jacobs
|
|
CA. Comparison of patient function during the first six weeks after direct anterior or posterior total hip arthroplasty (THA): A randomized study. Journal of Arthroplasty. 2015; 30:(9 Suppl):94–7 [<a href="https://pubmed.ncbi.nlm.nih.gov/26096071" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26096071</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>14.</dt><dd><div class="bk_ref" id="niceng157er13.ref14">Coyle
|
|
D, Coyle
|
|
K, Vale
|
|
L, de Verteuil
|
|
R, Imamura
|
|
M, Glazener
|
|
C
|
|
et al. Minimally invasive arthroplasty in the management of hip arthritic disease: Systematic review and economic evaluation. Ottawa. Canadian Agency for Drugs and Technologies in Health (CADTH), 2008. Available from: <a href="http://www.cadth.ca/media/pdf/336_Invasive-Arthroplasty-Man-Hip-Arthritic-Disease_tr_e.pdf" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.cadth.ca/media<wbr style="display:inline-block"></wbr>​/pdf/336_Invasive-Arthroplasty-Man-Hip-Arthritic-Disease_tr_e.pdf</a></div></dd></dl><dl class="bkr_refwrap"><dt>15.</dt><dd><div class="bk_ref" id="niceng157er13.ref15">D’Arrigo
|
|
C, Speranza
|
|
A, Monaco
|
|
E, Carcangiu
|
|
A, Ferretti
|
|
A. Learning curve in tissue sparing total hip replacement: Comparison between different approaches. Journal of Orthopaedics and Traumatology. 2009; 10(1):47–54 [<a href="/pmc/articles/PMC2657353/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2657353</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19384637" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19384637</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>16.</dt><dd><div class="bk_ref" id="niceng157er13.ref16">De Anta-Diaz
|
|
B, Serralta-Gomis
|
|
J, Lizaur-Utrilla
|
|
A, Benavidez
|
|
E, Lopez-Prats
|
|
FA. No differences between direct anterior and lateral approach for primary total hip arthroplasty related to muscle damage or functional outcome. International Orthopaedics. 2016; 40(10):2025–2030 [<a href="https://pubmed.ncbi.nlm.nih.gov/26753844" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26753844</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>17.</dt><dd><div class="bk_ref" id="niceng157er13.ref17">De Geest
|
|
T, Fennema
|
|
P, Lenaerts
|
|
G, De Loore
|
|
G. Adverse effects associated with the direct anterior approach for total hip arthroplasty: A Bayesian meta-analysis. Archives of Orthopaedic and Trauma Surgery. 2015; 135(8):1183–92 [<a href="https://pubmed.ncbi.nlm.nih.gov/26081800" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26081800</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>18.</dt><dd><div class="bk_ref" id="niceng157er13.ref18">de Verteuil
|
|
R, Imamura
|
|
M, Zhu
|
|
S, Glazener
|
|
C, Fraser
|
|
C, Munro
|
|
N
|
|
et al. A systematic review of the clinical effectiveness and cost-effectiveness and economic modelling of minimal incision total hip replacement approaches in the management of arthritic disease of the hip. Health Technology Assessment. 2008; 12(26):iii–iv, ix–223 [<a href="https://pubmed.ncbi.nlm.nih.gov/18513467" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18513467</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>19.</dt><dd><div class="bk_ref" id="niceng157er13.ref19">Della Valle
|
|
CJ, Dittle
|
|
E, Moric
|
|
M, Sporer
|
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SM, Buvanendran
|
|
A. A prospective randomized trial of mini-incision posterior and two-incision total hip arthroplasty. Clinical Orthopaedics and Related Research. 2010; 468:3348–54 [<a href="/pmc/articles/PMC2974893/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2974893</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/20668969" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20668969</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>20.</dt><dd><div class="bk_ref" id="niceng157er13.ref20">den Hartog
|
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YM, Mathijssen
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|
NM, Vehmeijer
|
|
SB. The less invasive anterior approach for total hip arthroplasty: A comparison to other approaches and an evaluation of the learning curve - a systematic review. Hip International. 2016; 26(2):105–20 [<a href="https://pubmed.ncbi.nlm.nih.gov/26951546" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26951546</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>21.</dt><dd><div class="bk_ref" id="niceng157er13.ref21">Department of Health. NHS reference costs 2017-18. 2018. Available from: <a href="https://improvement.nhs.uk/resources/reference-costs/#rc1718" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://improvement<wbr style="display:inline-block"></wbr>​.nhs<wbr style="display:inline-block"></wbr>​.uk/resources/reference-costs/#rc1718</a> Last accessed: 18/07/2019</div></dd></dl><dl class="bkr_refwrap"><dt>22.</dt><dd><div class="bk_ref" id="niceng157er13.ref22">Dienstknecht
|
|
T, Luring
|
|
C, Tingart
|
|
M, Grifka
|
|
J, Sendtner
|
|
E. A minimally invasive approach for total hip arthroplasty does not diminish early post-operative outcome in obese patients: A prospective, randomised trial. International Orthopaedics. 2013; 37(6):1013–8 [<a href="/pmc/articles/PMC3664165/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3664165</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23446330" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23446330</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>23.</dt><dd><div class="bk_ref" id="niceng157er13.ref23">Dienstknecht
|
|
T, Luring
|
|
C, Tingart
|
|
M, Grifka
|
|
J, Sendtner
|
|
E. Total hip arthroplasty through the mini-incision (Micro-hip) approach versus the standard transgluteal (Bauer) approach: A prospective, randomised study. Journal of Orthopaedic Surgery. 2014; 22(2):168–72 [<a href="https://pubmed.ncbi.nlm.nih.gov/25163948" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25163948</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>24.</dt><dd><div class="bk_ref" id="niceng157er13.ref24">Dorr
|
|
LD, Maheshwari
|
|
AV, Long
|
|
WT, Wan
|
|
Z, Sirianni
|
|
LE. Early pain relief and function after posterior minimally invasive and conventional total hip arthroplasty. A prospective, randomized, blinded study. Journal of Bone and Joint Surgery (American Volume). 2007; 89(6):1153–60 [<a href="https://pubmed.ncbi.nlm.nih.gov/17545416" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17545416</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>25.</dt><dd><div class="bk_ref" id="niceng157er13.ref25">Dutka
|
|
J, Sosin
|
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P, Libura
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|
M, Skowronek
|
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P. Total hip arthroplasty through a minimally invasive lateral approach-our experience and early results. Ortopedia Traumatologia Rehabilitacja. 2007; 9(1):39–45 [<a href="https://pubmed.ncbi.nlm.nih.gov/17514173" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17514173</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>26.</dt><dd><div class="bk_ref" id="niceng157er13.ref26">Eto
|
|
S, Hwang
|
|
K, Huddleston
|
|
JI, Amanatullah
|
|
DF, Maloney
|
|
WJ, Goodman
|
|
SB. The direct anterior approach is associated with early revision total hip arthroplasty. Journal of Arthroplasty. 2017; 32(3):1001–1005 [<a href="https://pubmed.ncbi.nlm.nih.gov/27843039" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27843039</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>27.</dt><dd><div class="bk_ref" id="niceng157er13.ref27">Fink
|
|
B, Mittelstaedt
|
|
A. Minimally invasive posterior approach for total hip arthroplasty. Der Orthopade. 2012; 41(5):382–389 [<a href="https://pubmed.ncbi.nlm.nih.gov/22581148" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22581148</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>28.</dt><dd><div class="bk_ref" id="niceng157er13.ref28">Gofton
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W, Fitch
|
|
DA. In-hospital cost comparison between the standard lateral and supercapsular percutaneously-assisted total hip surgical techniques for total hip replacement. International Orthopaedics. 2016; 40(3):481–5 [<a href="https://pubmed.ncbi.nlm.nih.gov/26156723" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26156723</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>29.</dt><dd><div class="bk_ref" id="niceng157er13.ref29">Goosen
|
|
JH, Kollen
|
|
BJ, Castelein
|
|
RM, Kuipers
|
|
BM, Verheyen
|
|
CC. Minimally invasive versus classic procedures in total hip arthroplasty: A double-blind randomized controlled trial. Clinical Orthopaedics and Related Research. 2011; 469:200–8 [<a href="/pmc/articles/PMC3008875/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3008875</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/20352383" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20352383</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>30.</dt><dd><div class="bk_ref" id="niceng157er13.ref30">Graves
|
|
SC, Dropkin
|
|
BM, Keeney
|
|
BJ, Lurie
|
|
JD, Tomek
|
|
IM. Does surgical approach affect patient-reported function after primary THA?
|
|
Clinical Orthopaedics and Related Research. 2016; 474:971–81 [<a href="/pmc/articles/PMC4773324/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4773324</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26620966" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26620966</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>31.</dt><dd><div class="bk_ref" id="niceng157er13.ref31">Greidanus
|
|
NV, Chihab
|
|
S, Garbuz
|
|
DS, Masri
|
|
BA, Tanzer
|
|
M, Gross
|
|
AE
|
|
et al. Outcomes of minimally invasive anterolateral THA are not superior to those of minimally invasive direct lateral and posterolateral THA. Clinical Orthopaedics and Related Research. 2013; 471:463–71 [<a href="/pmc/articles/PMC3549154/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3549154</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23073706" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23073706</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>32.</dt><dd><div class="bk_ref" id="niceng157er13.ref32">Gunther
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|
KP. Surgical approaches for osteoarthritis. Best Practice & Research: Clinical Rheumatology. 2001; 15(4):627–43 [<a href="https://pubmed.ncbi.nlm.nih.gov/11567544" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11567544</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>33.</dt><dd><div class="bk_ref" id="niceng157er13.ref33">Ha
|
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YC. Dislocation after total hip arthroplasty: A randomized clinical trial of a posterior approach and a modified lateral approach. Journal of Arthroplasty. 2013; 28(1):200 [<a href="https://pubmed.ncbi.nlm.nih.gov/23164838" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23164838</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>34.</dt><dd><div class="bk_ref" id="niceng157er13.ref34">Hendrickx
|
|
C, De Hertogh
|
|
W, Van Daele
|
|
U, Mertens
|
|
P, Stassijns
|
|
G. Effect of percutaneous assisted approach on functional rehabilitation for total hip replacement compared to anterolateral approach: Study protocol for a randomized controlled trial. Trials [Electronic Resource]. 2014; 15:392 [<a href="/pmc/articles/PMC4197322/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4197322</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25298243" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25298243</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>35.</dt><dd><div class="bk_ref" id="niceng157er13.ref35">Higgins
|
|
BT, Barlow
|
|
DR, Heagerty
|
|
NE, Lin
|
|
TJ. Anterior vs. posterior approach for total hip arthroplasty, a systematic review and meta-analysis. Journal of Arthroplasty. 2015; 30(3):419–34 [<a href="https://pubmed.ncbi.nlm.nih.gov/25453632" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25453632</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>36.</dt><dd><div class="bk_ref" id="niceng157er13.ref36">Hjorth
|
|
MH, Lorenzen
|
|
ND, Soballe
|
|
K, Jakobsen
|
|
SS, Stilling
|
|
M. Equal primary fixation of resurfacing stem, but inferior cup fixation with anterolateral vs posterior surgical approach. A 2-year blinded randomized radiostereometric and dual-energy x-ray absorptiometry study of metal-on-metal hip resurfacing arthroplasty. Journal of Arthroplasty. 2017; 32(11):3412–3420 [<a href="https://pubmed.ncbi.nlm.nih.gov/28641972" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28641972</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>37.</dt><dd><div class="bk_ref" id="niceng157er13.ref37">Horwitz
|
|
BR, Rockowitz
|
|
NL, Goll
|
|
SR, Booth
|
|
RE, Jr., Balderston
|
|
RA, Rothman
|
|
RH
|
|
et al. A prospective randomized comparison of two surgical approaches to total hip arthroplasty. Clinical Orthopaedics and Related Research. 1993; (291):154–63 [<a href="https://pubmed.ncbi.nlm.nih.gov/8504594" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8504594</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>38.</dt><dd><div class="bk_ref" id="niceng157er13.ref38">Hozack
|
|
WJ, Heller
|
|
S. Direct anterior hip exposure for total hip arthroplasty. Jbjs Essential Surgical Techniques. 2015; 5(4):e22 [<a href="/pmc/articles/PMC6203483/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6203483</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30405956" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30405956</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>39.</dt><dd><div class="bk_ref" id="niceng157er13.ref39">Hu
|
|
CC, Chern
|
|
JS, Hsieh
|
|
PH, Shih
|
|
CH, Ueng
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SW, Lee
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MS. Two-incision versus modified Watson-Jones total hip arthroplasty in the same patients- a prospective study of clinical outcomes and patient preferences. Chang Gung Medical Journal. 2012; 35(1):54–61 [<a href="https://pubmed.ncbi.nlm.nih.gov/22483428" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22483428</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>40.</dt><dd><div class="bk_ref" id="niceng157er13.ref40">Inaba
|
|
Y, Kobayashi
|
|
N, Yukizawa
|
|
Y, Ishida
|
|
T, Iwamoto
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N, Saito
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T. Little clinical advantage of modified Watson-Jones approach over modified mini-incision direct lateral approach in primary total hip arthroplasty. Journal of Arthroplasty. 2011; 26(7):1117–22 [<a href="https://pubmed.ncbi.nlm.nih.gov/21602025" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21602025</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>41.</dt><dd><div class="bk_ref" id="niceng157er13.ref41">Ji
|
|
HM, Kim
|
|
KC, Lee
|
|
YK, Ha
|
|
YC, Koo
|
|
KH. Dislocation after total hip arthroplasty: A randomized clinical trial of a posterior approach and a modified lateral approach. Journal of Arthroplasty. 2012; 27(3):378–85 [<a href="https://pubmed.ncbi.nlm.nih.gov/21802253" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21802253</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>42.</dt><dd><div class="bk_ref" id="niceng157er13.ref42">Jia
|
|
F, Guo
|
|
B, Xu
|
|
F, Hou
|
|
Y, Tang
|
|
X, Huang
|
|
L. A comparison of clinical, radiographic and surgical outcomes of total hip arthroplasty between direct anterior and posterior approaches: A systematic review and meta-analysis. Hip International. 2018; Epublication [<a href="https://pubmed.ncbi.nlm.nih.gov/30595060" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30595060</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>43.</dt><dd><div class="bk_ref" id="niceng157er13.ref43">Jolles
|
|
BM, Bogoch
|
|
ER. Surgical approach for total hip arthroplasty: Direct lateral or posterior?
|
|
Journal of Rheumatology. 2004; 31(9):1790–6 [<a href="https://pubmed.ncbi.nlm.nih.gov/15338502" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15338502</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>44.</dt><dd><div class="bk_ref" id="niceng157er13.ref44">Jolles
|
|
BM, Bogoch
|
|
ER. Posterior versus lateral surgical approach for total hip arthroplasty in adults with osteoarthritis. Cochrane Database of Systematic Reviews
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2006, Issue 3. Art. No.: CD003828. DOI: 10.1002/14651858.CD003828.pub3. [<a href="/pmc/articles/PMC8740306/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8740306</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/16856020" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16856020</span></a>] [<a href="http://dx.crossref.org/10.1002/14651858.CD003828.pub3" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd></dl><dl class="bkr_refwrap"><dt>45.</dt><dd><div class="bk_ref" id="niceng157er13.ref45">Khan
|
|
RJK, Maor
|
|
D, Hofmann
|
|
M, Haebich
|
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S. A comparison of a less invasive piriformissparing approach versus the standard posterior approach to the hip: A randomised controlled trial. Journal of Bone and Joint Surgery - Series B. 2012; 94 B(1):43–50 [<a href="https://pubmed.ncbi.nlm.nih.gov/22219246" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22219246</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>46.</dt><dd><div class="bk_ref" id="niceng157er13.ref46">Kucukdurmaz
|
|
F, Sukeik
|
|
M, Parvizi
|
|
J. A meta-analysis comparing the direct anterior with other approaches in primary total hip arthroplasty. Surgeon Journal of the Royal Colleges of Surgeons of Edinburgh & Ireland. 2018; Epublication [<a href="https://pubmed.ncbi.nlm.nih.gov/30361126" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30361126</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>47.</dt><dd><div class="bk_ref" id="niceng157er13.ref47">Kwon
|
|
MS, Kuskowski
|
|
M, Mulhall
|
|
KJ, Macaulay
|
|
W, Brown
|
|
TE, Saleh
|
|
KJ. Does surgical approach affect total hip arthroplasty dislocation rates?
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|
Clinical Orthopaedics and Related Research. 2006; 447:34–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/16741471" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16741471</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>48.</dt><dd><div class="bk_ref" id="niceng157er13.ref48">Landgraeber
|
|
S, Quitmann
|
|
H, Guth
|
|
S, Haversath
|
|
M, Kowalczyk
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W, Kecskemethy
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A
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et al. A prospective randomized peri- and post-operative comparison of the minimally invasive anterolateral approach versus the lateral approach. Orthopedic Reviews. 2013; 5(3):e19 [<a href="/pmc/articles/PMC3808794/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3808794</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24191179" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24191179</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>49.</dt><dd><div class="bk_ref" id="niceng157er13.ref49">Lee
|
|
GC, Marconi
|
|
D. Complications following direct anterior hip procedures: Costs to both patients and surgeons. Journal of Arthroplasty. 2015; 30:(9 Suppl):98–101 [<a href="https://pubmed.ncbi.nlm.nih.gov/26118568" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26118568</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>50.</dt><dd><div class="bk_ref" id="niceng157er13.ref50">Leuchte
|
|
S, Luchs
|
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A, Wohlrab
|
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D. Measurement of ground reaction forces after total hip arthroplasty using different surgical approaches. Zeitschrift für Orthopädie und Ihre Grenzgebiete. 2007; 145(1):74–80 [<a href="https://pubmed.ncbi.nlm.nih.gov/17345547" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17345547</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>51.</dt><dd><div class="bk_ref" id="niceng157er13.ref51">Lin
|
|
SJ, Huang
|
|
TW, Lin
|
|
PC, Kuo
|
|
FC, Peng
|
|
KT, Huang
|
|
KC
|
|
et al. A 10-year follow-up of two-incision and modified Watson-Jones total hip arthroplasty in patients with osteonecrosis of the femoral head. BioMed Research International. 2017; 2017:8915104 [<a href="/pmc/articles/PMC5366216/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5366216</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28386565" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28386565</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>52.</dt><dd><div class="bk_ref" id="niceng157er13.ref52">Lorenzen
|
|
ND, Stilling
|
|
M, Ulrich-Vinther
|
|
M, Trolle-Andersen
|
|
N, Pryno
|
|
T, Soballe
|
|
K
|
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et al. Increased post-operative ischemia in the femoral head found by microdialysis by the posterior surgical approach: A randomized clinical trial comparing surgical approaches in hip resurfacing arthroplasty. Archives of Orthopaedic and Trauma Surgery. 2013; 133(12):1735–45 [<a href="https://pubmed.ncbi.nlm.nih.gov/24100766" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24100766</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>53.</dt><dd><div class="bk_ref" id="niceng157er13.ref53">Luo
|
|
Z, Chen
|
|
M, Shang
|
|
X, Hu
|
|
F, Ni
|
|
Z, Cheng
|
|
P
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et al. Direct anterior approach versus posterolateral approach for total hip arthroplasty in the lateral decubitus position. National Medical Journal of China. 2016; 96(35):2807–2812 [<a href="https://pubmed.ncbi.nlm.nih.gov/27686547" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27686547</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>54.</dt><dd><div class="bk_ref" id="niceng157er13.ref54">Martin
|
|
R, Clayson
|
|
PE, Troussel
|
|
S, Fraser
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BP, Docquier
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|
PL. Anterolateral minimally invasive total hip arthroplasty: A prospective randomized controlled study with a follow-up of 1 year. Journal of Arthroplasty. 2011; 26(8):1362–1372 [<a href="https://pubmed.ncbi.nlm.nih.gov/21435823" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21435823</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>55.</dt><dd><div class="bk_ref" id="niceng157er13.ref55">Matziolis
|
|
D, Wassilew
|
|
G, Strube
|
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P, Matziolis
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G, Perka
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C. Differences in muscle trauma quantifiable in the laboratory between the minimally invasive anterolateral and transgluteal approach. Archives of Orthopaedic and Trauma Surgery. 2011; 131(5):651–5 [<a href="https://pubmed.ncbi.nlm.nih.gov/20953874" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20953874</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>56.</dt><dd><div class="bk_ref" id="niceng157er13.ref56">Mayr
|
|
E, Nogler
|
|
M, Benedetti
|
|
MG, Kessler
|
|
O, Reinthaler
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A, Krismer
|
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M
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et al. A prospective randomized assessment of earlier functional recovery in THA patients treated by minimally invasive direct anterior approach: A gait analysis study. Clinical Biomechanics. 2009; 24(10):812–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/19699566" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19699566</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>57.</dt><dd><div class="bk_ref" id="niceng157er13.ref57">Meermans
|
|
G, Konan
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S, Das
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R, Volpin
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A, Haddad
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FS. The direct anterior approach in total hip arthroplasty: A systematic review of the literature. Bone & Joint Journal. 2017; 99-B(6):732–740 [<a href="https://pubmed.ncbi.nlm.nih.gov/28566391" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28566391</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>58.</dt><dd><div class="bk_ref" id="niceng157er13.ref58">Meneghini
|
|
RM, Smits
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|
SA. Early discharge and recovery with three minimally invasive total hip arthroplasty approaches: A preliminary study. Clinical Orthopaedics and Related Research. 2009; 467:1431–7 [<a href="/pmc/articles/PMC2674169/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2674169</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19224307" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19224307</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>59.</dt><dd><div class="bk_ref" id="niceng157er13.ref59">Meneghini
|
|
RM, Smits
|
|
SA, Swinford
|
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RR, Bahamonde
|
|
RE. A randomized, prospective study of 3 minimally invasive surgical approaches in total hip arthroplasty: Comprehensive gait analysis. Journal of Arthroplasty. 2008; 23(6 Suppl 1):68–73 [<a href="https://pubmed.ncbi.nlm.nih.gov/18722305" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18722305</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>60.</dt><dd><div class="bk_ref" id="niceng157er13.ref60">Migliorini
|
|
F, Biagini
|
|
M, Rath
|
|
B, Meisen
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N, Tingart
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M, Eschweiler
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J. Total hip arthroplasty: Minimally invasive surgery or not? Meta-analysis of clinical trials. International Orthopaedics. 2019; 43(7):1573–1582 [<a href="https://pubmed.ncbi.nlm.nih.gov/30171273" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30171273</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>61.</dt><dd><div class="bk_ref" id="niceng157er13.ref61">Miller
|
|
LE, Gondusky
|
|
JS, Bhattacharyya
|
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S, Kamath
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AF, Boettner
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F, Wright
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J. Does surgical approach affect outcomes in total hip arthroplasty through 90 days of follow-up? A systematic review with meta-analysis. Journal of Arthroplasty. 2018; 33(4):1296–1302 [<a href="https://pubmed.ncbi.nlm.nih.gov/29195848" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29195848</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>62.</dt><dd><div class="bk_ref" id="niceng157er13.ref62">Miller
|
|
LE, Gondusky
|
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JS, Kamath
|
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AF, Boettner
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F, Wright
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J, Bhattacharyya
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S. Influence of surgical approach on complication risk in primary total hip arthroplasty. Acta Orthopaedica. 2018; 89(3):289–294 [<a href="/pmc/articles/PMC6055783/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6055783</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/29451051" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29451051</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>63.</dt><dd><div class="bk_ref" id="niceng157er13.ref63">Miller
|
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LE, Kamath
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AF, Boettner
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F, Bhattacharyya
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SK. In-hospital outcomes with anterior versus posterior approaches in total hip arthroplasty: Meta-analysis of randomized controlled trials. Journal of Pain Research. 2018; 11:1327–1334 [<a href="/pmc/articles/PMC6044341/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6044341</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30214269" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30214269</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>64.</dt><dd><div class="bk_ref" id="niceng157er13.ref64">Mjaaland
|
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KE, Kivle
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K, Svenningsen
|
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S, Pripp
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AH, Nordsletten
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L. Comparison of markers for muscle damage, inflammation, and pain using minimally invasive direct anterior versus direct lateral approach in total hip arthroplasty: A prospective, randomized, controlled trial. Journal of Orthopaedic Research. 2015; 33(9):1305–10 [<a href="https://pubmed.ncbi.nlm.nih.gov/25877694" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25877694</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>65.</dt><dd><div class="bk_ref" id="niceng157er13.ref65">Mouilhade
|
|
F, Matsoukis
|
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J, Oger
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P, Mandereau
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C, Brzakala
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V, Dujardin
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F. Component positioning in primary total hip replacement: A prospective comparative study of two anterolateral approaches, minimally invasive versus gluteus medius hemimyotomy. Orthopaedics & Traumatology, Surgery & Research. 2011; 97(1):14–21 [<a href="https://pubmed.ncbi.nlm.nih.gov/21236746" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21236746</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>66.</dt><dd><div class="bk_ref" id="niceng157er13.ref66">Mukka
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SS, Sayed-Noor
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AS. An update on surgical approaches in hip arthoplasty: Lateral versus posterior approach. Hip International. 2014; 24:(Suppl 10):S7–11 [<a href="https://pubmed.ncbi.nlm.nih.gov/24970037" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24970037</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>67.</dt><dd><div class="bk_ref" id="niceng157er13.ref67">Muller
|
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M, Schwachmeyer
|
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V, Tohtz
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S, Taylor
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WR, Duda
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GN, Perka
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C
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M, Tohtz
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S, Springer
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I, Dewey
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M, Perka
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C. Randomized controlled trial of abductor muscle damage in relation to the surgical approach for primary total hip replacement: Minimally invasive anterolateral versus modified direct lateral approach. Archives of Orthopaedic and Trauma Surgery. 2011; 131(2):179–89 [<a href="https://pubmed.ncbi.nlm.nih.gov/20490520" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20490520</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>69.</dt><dd><div class="bk_ref" id="niceng157er13.ref69">Murphy
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SB, Tannast
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M. Conventional vs minimally invasive total hip arthroplasty. A prospective study of rehabilitation and complications. Der Orthopade. 2006; 35(7):761–4, 766–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/16683130" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16683130</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>70.</dt><dd><div class="bk_ref" id="niceng157er13.ref70">Musil
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D, Stehli
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KJ. Minimally invasive anterolateral surgical approach for total hip arthroplasty: Seven-year results. Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca. 2013; 80(2):138–41 [<a href="https://pubmed.ncbi.nlm.nih.gov/23562258" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23562258</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>71.</dt><dd><div class="bk_ref" id="niceng157er13.ref71">Musil
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D, Stehlík
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J, Verner
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M. A comparison of operative invasiveness in minimally invasive anterolateral hip replacement (MIS-AL) and standard hip procedure, using biochemical markers. Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca. 2008; 75(1):16–20 [<a href="https://pubmed.ncbi.nlm.nih.gov/18315957" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18315957</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>72.</dt><dd><div class="bk_ref" id="niceng157er13.ref72">National Institute for Health and Care Excellence. Developing NICE guidelines: the manual [updated 2018]. London. National Institute for Health and Care Excellence, 2014. Available from: <a href="http://www.nice.org.uk/article/PMG20/chapter/1%20Introduction%20and%20overview" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.nice.org.uk<wbr style="display:inline-block"></wbr>​/article/PMG20/chapter<wbr style="display:inline-block"></wbr>​/1%20Introduction%20and%20overview</a> [<a href="https://pubmed.ncbi.nlm.nih.gov/26677490" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26677490</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>73.</dt><dd><div class="bk_ref" id="niceng157er13.ref73">National Joint Registry. 15th annual report. Hertfordshire. 2018. Available from: <a href="http://www.njrreports.org.uk/Portals/0/PDFdownloads/NJR%2015th%20Annual%20Report%202018.pdf" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.njrreports<wbr style="display:inline-block"></wbr>​.org.uk/Portals/0/PDFdownloads<wbr style="display:inline-block"></wbr>​/NJR%2015th<wbr style="display:inline-block"></wbr>​%20Annual%20Report%202018.pdf</a></div></dd></dl><dl class="bkr_refwrap"><dt>74.</dt><dd><div class="bk_ref" id="niceng157er13.ref74">Nistor
|
|
DV, Caterev
|
|
S, Bolboaca
|
|
SD, Cosma
|
|
D, Lucaciu
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DOG, Todor
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|
|
DA, Rorabeck
|
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CH. The mini-incision direct lateral approach in primary total hip arthroplasty. Clinical Orthopaedics and Related Research. 2005; 441:99–103 [<a href="https://pubmed.ncbi.nlm.nih.gov/16330991" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16330991</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>76.</dt><dd><div class="bk_ref" id="niceng157er13.ref76">Ogonda
|
|
L, Wilson
|
|
R, Archbold
|
|
P, Lawlor
|
|
M, Humphreys
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|
P, O’Brien
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S
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et al. A minimal-incision technique in total hip arthroplasty does not improve early postoperative outcomes. A prospective, randomized, controlled trial. Journal of Bone and Joint Surgery (American Volume). 2005; 87(4):701–10 [<a href="https://pubmed.ncbi.nlm.nih.gov/15805196" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15805196</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>77.</dt><dd><div class="bk_ref" id="niceng157er13.ref77">Organisation for Economic Co-operation and Development (OECD). Purchasing power parities (PPP). 2012. Available from: <a href="http://www.oecd.org/std/ppp" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.oecd.org/std/ppp</a> Last accessed: 17/06/2019</div></dd></dl><dl class="bkr_refwrap"><dt>78.</dt><dd><div class="bk_ref" id="niceng157er13.ref78">Ouyang
|
|
C, Wang
|
|
H, Meng
|
|
W, Luo
|
|
Z, Wang
|
|
D, Pei
|
|
F
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et al. Randomized controlled trial of comparison between the SuperPATH and posterolateral approaches in total hip arthroplasty. Zhongguo xiu fu chong jian wai ke za zhi [Chinese journal of reparative and reconstructive surgery]. 2018; 32(12):1500–1506 [<a href="/pmc/articles/PMC8414232/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8414232</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30569673" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30569673</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>79.</dt><dd><div class="bk_ref" id="niceng157er13.ref79">Pai
|
|
VS. A comparison of three lateral approaches in primary total hip replacement. International Orthopaedics. 1997; 21(6):393–8 [<a href="/pmc/articles/PMC3619565/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3619565</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/9498150" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 9498150</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>80.</dt><dd><div class="bk_ref" id="niceng157er13.ref80">Parker
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|
M, Pervez
|
|
H. Surgical approaches for inserting hemiarthroplasty of the hip. Cochrane Database of Systematic Reviews
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2002, Issue 3. Art. No.: CD001707. DOI: 10.1002/14651858.CD001707. [<a href="/pmc/articles/PMC8407378/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC8407378</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/12137630" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 12137630</span></a>] [<a href="http://dx.crossref.org/10.1002/14651858.CD001707" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd></dl><dl class="bkr_refwrap"><dt>81.</dt><dd><div class="bk_ref" id="niceng157er13.ref81">Parvizi
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|
J, Restrepo
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|
C, Maltenfort
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|
MG. Total hip arthroplasty performed through direct anterior approach provides superior early outcome: Results of a randomized, prospective study. Orthopedic Clinics of North America. 2016; 47(3):497–504 [<a href="https://pubmed.ncbi.nlm.nih.gov/27241374" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27241374</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>82.</dt><dd><div class="bk_ref" id="niceng157er13.ref82">Petis
|
|
SM, Howard
|
|
JL, Lanting
|
|
BA, Marsh
|
|
JD, Vasarhelyi
|
|
EM. In-hospital cost analysis of total hip arthroplasty: Does surgical approach matter?
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Journal of Arthroplasty. 2016; 31(1):53–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/26387922" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26387922</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>83.</dt><dd><div class="bk_ref" id="niceng157er13.ref83">Pospischill
|
|
M, Kranzl
|
|
A, Attwenger
|
|
B, Knahr
|
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K. Minimally invasive compared with traditional transgluteal approach for total hip arthroplasty: A comparative gait analysis. Journal of Bone and Joint Surgery (American Volume). 2010; 92(2):328–37 [<a href="https://pubmed.ncbi.nlm.nih.gov/20124059" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20124059</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>84.</dt><dd><div class="bk_ref" id="niceng157er13.ref84">Putananon
|
|
C, Tuchinda
|
|
H, Arirachakaran
|
|
A, Wongsak
|
|
S, Narinsorasak
|
|
T, Kongtharvonskul
|
|
J. Comparison of direct anterior, lateral, posterior and posterior-2 approaches in total hip arthroplasty: Network meta-analysis. European Journal of Orthopaedic Surgery & Traumatology. 2018; 28(2):255–267 [<a href="https://pubmed.ncbi.nlm.nih.gov/28956180" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28956180</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>85.</dt><dd><div class="bk_ref" id="niceng157er13.ref85">Queen
|
|
RM, Appleton
|
|
JS, Butler
|
|
RJ, Newman
|
|
ET, Kelley
|
|
SS, Attarian
|
|
DE
|
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et al. Total hip arthroplasty surgical approach does not alter postoperative gait mechanics one year after surgery. Pm & R. 2014; 6(3):221–6; quiz 226 [<a href="https://pubmed.ncbi.nlm.nih.gov/24056161" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24056161</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>86.</dt><dd><div class="bk_ref" id="niceng157er13.ref86">Radoicic
|
|
D, Zec
|
|
V, Elassuity
|
|
WI, Azab
|
|
MA. Patient’s perspective on direct anterior versus posterior approach total hip arthroplasty. International Orthopaedics. 2018; 42(12):2771–2775 [<a href="https://pubmed.ncbi.nlm.nih.gov/29858616" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29858616</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>87.</dt><dd><div class="bk_ref" id="niceng157er13.ref87">Reichert
|
|
JC, von Rottkay
|
|
E, Roth
|
|
F, Renz
|
|
T, Hausmann
|
|
J, Kranz
|
|
J
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et al. A prospective randomized comparison of the minimally invasive direct anterior and the transgluteal approach for primary total hip arthroplasty. BMC Musculoskeletal Disorders. 2018; 19(1):241 [<a href="/pmc/articles/PMC6053824/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6053824</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30025519" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30025519</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>88.</dt><dd><div class="bk_ref" id="niceng157er13.ref88">Reininga
|
|
IH, Stevens
|
|
M, Wagenmakers
|
|
R, Boerboom
|
|
AL, Groothoff
|
|
JW, Bulstra
|
|
SK
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et al. Comparison of gait in patients following a computer-navigated minimally invasive anterior approach and a conventional posterolateral approach for total hip arthroplasty: A randomized controlled trial. Journal of Orthopaedic Research. 2013; 31(2):288–94 [<a href="https://pubmed.ncbi.nlm.nih.gov/22886805" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22886805</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>89.</dt><dd><div class="bk_ref" id="niceng157er13.ref89">Repantis
|
|
T, Bouras
|
|
T, Korovessis
|
|
P. Comparison of minimally invasive approach versus conventional anterolateral approach for total hip arthroplasty: A randomized controlled trial. European Journal of Orthopaedic Surgery & Traumatology. 2015; 25(1):111–6 [<a href="https://pubmed.ncbi.nlm.nih.gov/24557411" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24557411</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>90.</dt><dd><div class="bk_ref" id="niceng157er13.ref90">Restrepo
|
|
C, Parvizi
|
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J, Pour
|
|
AE, Hozack
|
|
WJ. Prospective randomized study of two surgical approaches for total hip arthroplasty. Journal of Arthroplasty. 2010; 25(5):671–9.e1 [<a href="https://pubmed.ncbi.nlm.nih.gov/20378307" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20378307</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>91.</dt><dd><div class="bk_ref" id="niceng157er13.ref91">Rittmeister
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|
M, Peters
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A. Comparison of total hip arthroplasty via a posterior mini-incision versus a classic anterolateral approach. Der Orthopade. 2006; 35(7):716, 718–22 [<a href="https://pubmed.ncbi.nlm.nih.gov/16688429" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16688429</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>92.</dt><dd><div class="bk_ref" id="niceng157er13.ref92">Rodriguez
|
|
JA, Deshmukh
|
|
AJ, Rathod
|
|
PA, Greiz
|
|
ML, Deshmane
|
|
PP, Hepinstall
|
|
MS
|
|
et al. Does the direct anterior approach in THA offer faster rehabilitation and comparable safety to the posterior approach?
|
|
Clinical Orthopaedics and Related Research. 2014; 472:455–63 [<a href="/pmc/articles/PMC3890195/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3890195</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23963704" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23963704</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>93.</dt><dd><div class="bk_ref" id="niceng157er13.ref93">Rosenlund
|
|
S, Broeng
|
|
L, Holsgaard-Larsen
|
|
A, Jensen
|
|
C, Overgaard
|
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S. Patient-reported outcome after total hip arthroplasty: Comparison between lateral and posterior approach. Acta Orthopaedica. 2017; 88(3):239–247 [<a href="/pmc/articles/PMC5434589/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5434589</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28464754" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28464754</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>94.</dt><dd><div class="bk_ref" id="niceng157er13.ref94">Rosenlund
|
|
S, Broeng
|
|
L, Jensen
|
|
C, Holsgaard-Larsen
|
|
A, Overgaard
|
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S. The effect of posterior and lateral approach on patient-reported outcome measures and physical function in patients with osteoarthritis, undergoing total hip replacement: A randomised controlled trial protocol. BMC Musculoskeletal Disorders. 2014; 15:354 [<a href="/pmc/articles/PMC4216831/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4216831</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25345483" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25345483</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>95.</dt><dd><div class="bk_ref" id="niceng157er13.ref95">Rosenlund
|
|
S, Broeng
|
|
L, Overgaard
|
|
S, Jensen
|
|
C, Holsgaard-Larsen
|
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A. The efficacy of modified direct lateral versus posterior approach on gait function and hip muscle strength after primary total hip arthroplasty at 12months follow-up. An explorative randomised controlled trial. Clinical Biomechanics. 2016; 39:91–99 [<a href="https://pubmed.ncbi.nlm.nih.gov/27721093" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27721093</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>96.</dt><dd><div class="bk_ref" id="niceng157er13.ref96">Rykov
|
|
K, Reininga
|
|
IHF, Knobben
|
|
BAS, Sietsma
|
|
MS, Ten Have
|
|
BLEF. The design of a randomised controlled trial to evaluate the (cost-) effectiveness of the posterolateral versus the direct anterior approach for THA (POLADA - trial). BMC Musculoskeletal Disorders. 2016; 17(1):1–9 [<a href="/pmc/articles/PMC5111237/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5111237</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/27846875" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27846875</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>97.</dt><dd><div class="bk_ref" id="niceng157er13.ref97">Rykov
|
|
K, Reininga
|
|
IHF, Sietsma
|
|
MS, Knobben
|
|
BAS, Ten Have
|
|
B. Posterolateral vs direct anterior approach in total hip arthroplasty (POLADA Trial): A randomized controlled trial to assess differences in serum markers. Journal of Arthroplasty. 2017; 32(12):3652–3658.e1 [<a href="https://pubmed.ncbi.nlm.nih.gov/28780222" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28780222</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>98.</dt><dd><div class="bk_ref" id="niceng157er13.ref98">Salineros
|
|
M, Wimmer
|
|
M, Schwenke
|
|
T, Jacobs
|
|
JJ, Hille
|
|
E, Honl
|
|
M. The medial approach in primary total hip replacement surgery, a prospective randomized study. American Academy of Orthopaedic Surgeons Annual Meeting. 2007;</div></dd></dl><dl class="bkr_refwrap"><dt>99.</dt><dd><div class="bk_ref" id="niceng157er13.ref99">Sander
|
|
K, Layher
|
|
F, Babisch
|
|
J, Roth
|
|
A. Evaluation of results after total hip replacement using a minimally invasive and a conventional approach. Clinical scores and gait analysis. Zeitschrift für Orthopädie und Ihre Grenzgebiete. 2011; 149(2):191–199 [<a href="https://pubmed.ncbi.nlm.nih.gov/21243592" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21243592</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>100.</dt><dd><div class="bk_ref" id="niceng157er13.ref100">Schwarze
|
|
M, Budde
|
|
S, von Lewinski
|
|
G, Windhagen
|
|
H, Keller
|
|
MC, Seehaus
|
|
F
|
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et al. No effect of conventional vs. minimally invasive surgical approach on clinical outcome and migration of a short stem total hip prosthesis at 2-year follow-up: A randomized controlled study. Clinical Biomechanics. 2018; 51:105–112 [<a href="https://pubmed.ncbi.nlm.nih.gov/29287171" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29287171</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>101.</dt><dd><div class="bk_ref" id="niceng157er13.ref101">Sendtner
|
|
E, Borowiak
|
|
K, Schuster
|
|
T, Woerner
|
|
M, Grifka
|
|
J, Renkawitz
|
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T. Tackling the learning curve: Comparison between the anterior, minimally invasive (Micro-hip) and the lateral, transgluteal (Bauer) approach for primary total hip replacement. Archives of Orthopaedic and Trauma Surgery. 2011; 131(5):597–602 [<a href="https://pubmed.ncbi.nlm.nih.gov/20721570" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20721570</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>102.</dt><dd><div class="bk_ref" id="niceng157er13.ref102">Sharma
|
|
R, Abdulla
|
|
I, Fairgrieve-Park
|
|
L, Mahdavi
|
|
S, Burkart
|
|
B, Bakal
|
|
J. Surgical approaches in total hip arthroplasty cost per case analysis: A retrospective, matched, micro-costing analysis in a socialised healthcare system. Hip International. 2019; Epublication [<a href="https://pubmed.ncbi.nlm.nih.gov/30938177" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30938177</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>103.</dt><dd><div class="bk_ref" id="niceng157er13.ref103">Sharma
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|
S, Bhamra
|
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MS. A prospective randomised pilot study to compare early post-operative recovery after conventional versus minimal incision posterior approach for total hip joint replacement. The Journal of Bone and Joint Surgery (Proceedings). 2006; 88-B(Suppl I):63–6c</div></dd></dl><dl class="bkr_refwrap"><dt>104.</dt><dd><div class="bk_ref" id="niceng157er13.ref104">Speranza
|
|
A, Iorio
|
|
R, Ferretti
|
|
M, D’Arrigo
|
|
C, Ferretti
|
|
A. A lateral minimal-incision technique in total hip replacement: A prospective, randomized, controlled trial. Hip International. 2007; 17(1):4–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/19197836" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19197836</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>105.</dt><dd><div class="bk_ref" id="niceng157er13.ref105">Takada
|
|
R, Jinno
|
|
T, Miyatake
|
|
K, Hirao
|
|
M, Kimura
|
|
A, Koga
|
|
D
|
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et al. Direct anterior versus anterolateral approach in one-stage supine total hip arthroplasty. Focused on nerve injury: A prospective, randomized, controlled trial. Journal of Orthopaedic Science. 2018; 23(5):783–787 [<a href="https://pubmed.ncbi.nlm.nih.gov/29935972" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29935972</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>106.</dt><dd><div class="bk_ref" id="niceng157er13.ref106">Talia
|
|
AJ, Coetzee
|
|
C, Tirosh
|
|
O, Tran
|
|
P. Comparison of outcome measures and complication rates following three different approaches for primary total hip arthroplasty: A pragmatic randomised controlled trial. Trials [Electronic Resource]. 2018; 19:13 [<a href="/pmc/articles/PMC5759198/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5759198</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/29310681" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29310681</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>107.</dt><dd><div class="bk_ref" id="niceng157er13.ref107">Tanavalee
|
|
A, Jaruwannapong
|
|
S, Yuktanandana
|
|
P, Itiravivong
|
|
P. Early outcomes following minimally invasive total hip arthroplasty using a two-incision approach versus a mini-posterior approach. Hip International. 2006; 16:(Suppl 4):17–22 [<a href="https://pubmed.ncbi.nlm.nih.gov/19219824" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19219824</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>108.</dt><dd><div class="bk_ref" id="niceng157er13.ref108">Taunton
|
|
MJ, Mason
|
|
JB, Odum
|
|
SM, Springer
|
|
BD. Direct anterior total hip arthroplasty yields more rapid voluntary cessation of all walking aids: A prospective, randomized clinical trial. Journal of Arthroplasty. 2014; 29:(9 Suppl):169–72 [<a href="https://pubmed.ncbi.nlm.nih.gov/25007723" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25007723</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>109.</dt><dd><div class="bk_ref" id="niceng157er13.ref109">Taunton
|
|
MJ, Trousdale
|
|
RT, Sierra
|
|
RJ, Kaufman
|
|
K, Pagnano
|
|
MW. John charnley award: Randomized clinical trial of direct anterior and miniposterior approach THA: Which provides better functional recovery?
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Clinical Orthopaedics and Related Research. 2018; 476(2):216–229 [<a href="/pmc/articles/PMC6259722/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6259722</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/29529650" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29529650</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>110.</dt><dd><div class="bk_ref" id="niceng157er13.ref110">Tjur
|
|
M, Pedersen
|
|
AR, Sloth
|
|
W, Soballe
|
|
K, Lorenzen
|
|
ND, Stilling
|
|
M. Posterior or anterolateral approach in hip joint arthroplasty - Impact on frontal plane moment. Clinical Biomechanics. 2018; 54:143–150 [<a href="https://pubmed.ncbi.nlm.nih.gov/29587148" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29587148</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>111.</dt><dd><div class="bk_ref" id="niceng157er13.ref111">Varela-Egocheaga
|
|
JR, Suarez-Suarez
|
|
MA, Fernandez-Villan
|
|
M, Gonzalez-Sastre
|
|
V, Varela-Gomez
|
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JR, Murcia-Mazon
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A. Minimally invasive posterior approach in total hip arthroplasty. Prospective randomised trial. Anales del Sistema Sanitario de Navarra. 2010; 33(2):133–143 [<a href="https://pubmed.ncbi.nlm.nih.gov/20927140" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20927140</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>112.</dt><dd><div class="bk_ref" id="niceng157er13.ref112">Varela-Egocheaga
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JR, Suarez-Suarez
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MA, Fernandez-Villan
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M, Gonzalez-Sastre
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V, Varela-Gomez
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JR, Murcia-Mazon
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A. Minimally invasive hip surgery: The approach did not make the difference. European Journal of Orthopaedic Surgery & Traumatology. 2013; 23(1):47–52 [<a href="https://pubmed.ncbi.nlm.nih.gov/23412407" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23412407</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>113.</dt><dd><div class="bk_ref" id="niceng157er13.ref113">Wang
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Z, Hou
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JZ, Wu
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CH, Zhou
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YJ, Gu
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XM, Wang
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HH
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et al. A systematic review and meta-analysis of direct anterior approach versus posterior approach in total hip arthroplasty. Journal of Orthopaedic Surgery and Research. 2018; 13(1):229 [<a href="/pmc/articles/PMC6127950/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC6127950</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/30189881" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30189881</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>114.</dt><dd><div class="bk_ref" id="niceng157er13.ref114">Whatling
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GM, Dabke
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HV, Holt
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CA, Jones
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L, Madete
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J, Alderman
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PM
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et al. Objective functional assessment of total hip arthroplasty following two common surgical approaches: The posterior and direct lateral approaches. Proceedings of the Institution of Mechanical Engineers Part H - Journal of Engineering in Medicine. 2008; 222(6):897–905 [<a href="https://pubmed.ncbi.nlm.nih.gov/18935806" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18935806</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>115.</dt><dd><div class="bk_ref" id="niceng157er13.ref115">Witzleb
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WC, Stephan
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L, Krummenauer
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F, Neuke
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A, Gunther
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KP. Short-term outcome after posterior versus lateral surgical approach for total hip arthroplasty - A randomized clinical trial. European Journal of Medical Research. 2009; 14(6):256–63 [<a href="/pmc/articles/PMC3352018/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3352018</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19541586" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19541586</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>116.</dt><dd><div class="bk_ref" id="niceng157er13.ref116">Wohlrab
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D, Droege
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JW, Mendel
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T, Brehme
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K, Riedl
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K, Leuchte
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S
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et al. Minimally invasive vs. transgluteal total hip replacement. A 3-month follow-up of a prospective randomized clinical study. Der Orthopade. 2008; 37(11):1121–1126 [<a href="https://pubmed.ncbi.nlm.nih.gov/18810386" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18810386</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>117.</dt><dd><div class="bk_ref" id="niceng157er13.ref117">Wohlrab
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D, Hagel
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A, Hein
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W. Advantages of minimal invasive total hip replacement in the early phase of rehabilitation. Zeitschrift für Orthopädie und Ihre Grenzgebiete. 2004; 142(6):685–690 [<a href="https://pubmed.ncbi.nlm.nih.gov/15614648" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15614648</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>118.</dt><dd><div class="bk_ref" id="niceng157er13.ref118">Xie
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J, Zhang
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H, Wang
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L, Yao
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X, Pan
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Z, Jiang
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Q. Comparison of supercapsular percutaneously assisted approach total hip versus conventional posterior approach for total hip arthroplasty: A prospective, randomized controlled trial. Journal of Orthopaedic Surgery and Research. 2017; 12(1):138 [<a href="/pmc/articles/PMC5613398/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5613398</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28946892" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28946892</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>119.</dt><dd><div class="bk_ref" id="niceng157er13.ref119">Xu
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CP, Li
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X, Song
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JQ, Cui
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Z, Yu
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B. Mini-incision versus standard incision total hip arthroplasty regarding surgical outcomes: A systematic review and meta-analysis of randomized controlled trials. PloS One. 2013; 8(11):e80021 [<a href="/pmc/articles/PMC3827164/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3827164</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24265792" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24265792</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>120.</dt><dd><div class="bk_ref" id="niceng157er13.ref120">Xu
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J, Zhuang
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WD, Li
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XW, Yu
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GY, Lin
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Y, Luo
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FQ
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et al. Comparison of the effects of total hip arthroplasty via direct anterior approach and posterolateral piriformis-sparing approach. Beijing da xue xue bao [Journal of Peking University Health sciences]. 2017; 49(2):214–220 [<a href="https://pubmed.ncbi.nlm.nih.gov/28416827" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28416827</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>121.</dt><dd><div class="bk_ref" id="niceng157er13.ref121">Yamamoto
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M, Malay
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S, Fujihara
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Y, Zhong
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L, Chung
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KC. A systematic review of different implants and approaches for proximal interphalangeal joint arthroplasty. Plastic and Reconstructive Surgery. 2017; 139(5):1139e–1151e [<a href="/pmc/articles/PMC5407295/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5407295</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28445369" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28445369</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>122.</dt><dd><div class="bk_ref" id="niceng157er13.ref122">Yan
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ZQ, Chen
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YS, Yang
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Y, Li
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WJ, Chen
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ZR, Zhang
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GJ. Two-incision minimal invasive approach for total hip replacement. Fudan University Journal of Medical Sciences. 2005; 32(5):557–560</div></dd></dl><dl class="bkr_refwrap"><dt>123.</dt><dd><div class="bk_ref" id="niceng157er13.ref123">Yang
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B, Li
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H, He
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X, Wang
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G, Xu
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S. Minimally invasive surgical approaches and traditional total hip arthroplasty: A meta-analysis of radiological and complications outcomes. PloS One. 2012; 7(5):e37947 [<a href="/pmc/articles/PMC3360020/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3360020</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/22655086" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22655086</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>124.</dt><dd><div class="bk_ref" id="niceng157er13.ref124">Yang
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C, Zhu
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Q, Han
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Y, Zhu
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J, Wang
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H, Cong
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R
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et al. Minimally-invasive total hip arthroplasty will improve early postoperative outcomes: A prospective, randomized, controlled trial. Irish Journal of Medical Science. 2010; 179(2):285–90 [<a href="https://pubmed.ncbi.nlm.nih.gov/19847593" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19847593</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>125.</dt><dd><div class="bk_ref" id="niceng157er13.ref125">Yang
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CF, Zhu
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QS, Han
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YS, Zhu
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JY, Wang
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HQ, Cong
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R
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et al. Anterolateral minimally-invasive total hip arthroplasty: A clinical comparative study of 110 cases. Zhonghua Yi Xue Za Zhi Chinese Medical Journal (Taipei). 2009; 89(1):2–6 [<a href="https://pubmed.ncbi.nlm.nih.gov/19489234" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19489234</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>126.</dt><dd><div class="bk_ref" id="niceng157er13.ref126">Yue
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C, Kang
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P, Pei
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F. Comparison of direct anterior and lateral approaches in total hip arthroplasty: A systematic review and meta-analysis (PRISMA). Medicine. 2015; 94(50):e2126 [<a href="/pmc/articles/PMC5058892/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5058892</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26683920" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26683920</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>127.</dt><dd><div class="bk_ref" id="niceng157er13.ref127">Zhang
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XL, Wang
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Q, Jiang
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Y, Zeng
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BF. Minimally invasive total hip arthroplasty with anterior incision. Zhonghua Wai Ke Za Zhi Chinese Journal of Surgery. 2006; 44(8):512–515 [<a href="https://pubmed.ncbi.nlm.nih.gov/16784623" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16784623</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>128.</dt><dd><div class="bk_ref" id="niceng157er13.ref128">Zhao
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HY, Kang
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PD, Xia
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YY, Shi
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XJ, Nie
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Y, Pei
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FX. Comparison of early functional recovery after total hip arthroplasty using a direct anterior or posterolateral approach: A randomized controlled trial. Journal of Arthroplasty. 2017; 32(11):3421–3428 [<a href="https://pubmed.ncbi.nlm.nih.gov/28662957" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28662957</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>129.</dt><dd><div class="bk_ref" id="niceng157er13.ref129">Zheng
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KD, He
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P, Rong
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XC, Huang
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WH, Yao
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ZL. Lateral versus posterolateral approach in total hip arthroplasty: Restoration of joint function in 2-year follow-up. Chinese Journal of Tissue Engineering Research. 2014; 18(31):4929–4933</div></dd></dl><dl class="bkr_refwrap"><dt>130.</dt><dd><div class="bk_ref" id="niceng157er13.ref130">Zomar
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BO, Bryant
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D, Hunter
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S, Howard
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JL, Vasarhelyi
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EM, Lanting
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BA. A randomised trial comparing spatio-temporal gait parameters after total hip arthroplasty between the direct anterior and direct lateral surgical approaches. Hip International. 2018; 28(5):478–484 [<a href="https://pubmed.ncbi.nlm.nih.gov/29781289" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29781289</span></a>]</div></dd></dl></dl></div><div id="appendixesappgroup1"><h2 id="_appendixesappgroup1_">Appendices</h2><div id="niceng157er13.appa"><h3>Appendix A. Review protocols</h3><p id="niceng157er13.appa.et1"><a href="/books/NBK561418/bin/niceng157er13-appa-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Table 9. Review protocol: Hip replacement surgery</a><span class="small"> (PDF, 231K)</span></p><p id="niceng157er13.appa.tab1"><a href="/books/NBK561418/table/niceng157er13.appa.tab1/?report=objectonly" target="object" rid-ob="figobniceng157er13appatab1" class="figpopup">Table 10. Health economic review protocol</a></p></div><div id="niceng157er13.appb"><h3>Appendix B. Literature search strategies</h3><p>The literature searches for this review are detailed below and complied with the methodology outlined in Developing NICE guidelines: the manual 2014.<a class="bibr" href="#niceng157er13.ref72" rid="niceng157er13.ref72"><sup>72</sup></a></p><p><i>For more detailed information, please see the</i>
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<a href="/books/NBK561418/bin/niceng157er13_bm1.pdf">Methodology Review</a>.</p><div id="niceng157er13.appb.s1"><h4>B.1. Clinical search literature search strategy</h4><p>Searches were constructed using a PICO framework where population (P) terms were combined with Intervention (I) and in some cases Comparison (C) terms. Outcomes (O) are rarely used in search strategies for interventions as these concepts may not be well described in title, abstract or indexes and therefore difficult to retrieve. Search filters were applied to the searches where appropriate.</p><p id="niceng157er13.appb.tab1"><a href="/books/NBK561418/table/niceng157er13.appb.tab1/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab1" class="figpopup">Table 11. Database date parameters and filters used</a></p><p id="niceng157er13.appb.tab2"><a href="/books/NBK561418/table/niceng157er13.appb.tab2/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab2" class="figpopup">Medline (Ovid) search terms</a></p><p id="niceng157er13.appb.tab3"><a href="/books/NBK561418/table/niceng157er13.appb.tab3/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab3" class="figpopup">Embase (Ovid) search terms</a></p><p id="niceng157er13.appb.tab4"><a href="/books/NBK561418/table/niceng157er13.appb.tab4/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab4" class="figpopup">Cochrane Library (Wiley) search terms</a></p></div><div id="niceng157er13.appb.s2"><h4>B.2. Health Economics literature search strategy</h4><p>Health economic evidence was identified by conducting a broad search relating to joint replacement population in NHS Economic Evaluation Database (NHS EED – this ceased to be updated after March 2015) and the Health Technology Assessment database (HTA) with no date restrictions. NHS EED and HTA databases are hosted by the Centre for Research and Dissemination (CRD). Additional health economics searches were run on Medline and Embase.</p><p id="niceng157er13.appb.tab5"><a href="/books/NBK561418/table/niceng157er13.appb.tab5/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab5" class="figpopup">Table 12. Database date parameters and filters used</a></p><p id="niceng157er13.appb.tab6"><a href="/books/NBK561418/table/niceng157er13.appb.tab6/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab6" class="figpopup">Medline (Ovid) search terms</a></p><p id="niceng157er13.appb.tab7"><a href="/books/NBK561418/table/niceng157er13.appb.tab7/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab7" class="figpopup">Embase (Ovid) search terms</a></p><p id="niceng157er13.appb.tab8"><a href="/books/NBK561418/table/niceng157er13.appb.tab8/?report=objectonly" target="object" rid-ob="figobniceng157er13appbtab8" class="figpopup">NHS EED and HTA (CRD) search terms</a></p></div></div><div id="niceng157er13.appc"><h3>Appendix C. Clinical evidence selection</h3><p id="niceng157er13.appc.fig1"><a href="/books/NBK561418/figure/niceng157er13.appc.fig1/?report=objectonly" target="object" rid-ob="figobniceng157er13appcfig1" class="figpopup">Figure 1. Flow chart of clinical study selection for the review of hip replacement</a></p></div><div id="niceng157er13.appd"><h3>Appendix D. Clinical evidence tables</h3><p id="niceng157er13.appd.et1"><a href="/books/NBK561418/bin/niceng157er13-appd-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Download PDF</a><span class="small"> (731K)</span></p></div><div id="niceng157er13.appe"><h3>Appendix E. Forest plots</h3><div id="niceng157er13.appe.s1"><h4>E.1. Direct anterior vs anterolateral</h4><p id="niceng157er13.appe.fig1"><a href="/books/NBK561418/figure/niceng157er13.appe.fig1/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig1" class="figpopup">Figure 2. Quality of life, SF-12 and SF-36 scale, mental subscales, high is good outcome, 6 weeks or earlier</a></p><p id="niceng157er13.appe.fig2"><a href="/books/NBK561418/figure/niceng157er13.appe.fig2/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig2" class="figpopup">Figure 3. Quality of life, SF-12 and SF-36 scale, physical subscales, high is good outcome, 6 weeks or earlier</a></p><p id="niceng157er13.appe.fig3"><a href="/books/NBK561418/figure/niceng157er13.appe.fig3/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig3" class="figpopup">Figure 4. Quality of life, SF-12 and SF-36 scale, mental subscales, high is good outcome, later than 6 weeks up to 1 year</a></p><p id="niceng157er13.appe.fig4"><a href="/books/NBK561418/figure/niceng157er13.appe.fig4/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig4" class="figpopup">Figure 5. Quality of life, SF-12 and SF-36 scale, physical subscales, high is good outcome, later than 6 weeks up to 1 year</a></p><p id="niceng157er13.appe.fig5"><a href="/books/NBK561418/figure/niceng157er13.appe.fig5/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig5" class="figpopup">Figure 6. PROMs, WOMAC, total score, high is good, 6 weeks or earlier</a></p><p id="niceng157er13.appe.fig6"><a href="/books/NBK561418/figure/niceng157er13.appe.fig6/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig6" class="figpopup">Figure 7. PROMs, Harris Hip Score, 0-100, high is good, 6 weeks or earlier</a></p><p id="niceng157er13.appe.fig7"><a href="/books/NBK561418/figure/niceng157er13.appe.fig7/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig7" class="figpopup">Figure 8. PROMs, WOMAC, total score, high is good, later than 6 weeks up to 1 year</a></p><p id="niceng157er13.appe.fig8"><a href="/books/NBK561418/figure/niceng157er13.appe.fig8/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig8" class="figpopup">Figure 9. PROMs, Harris Hip Score, 0-100, high is good, later than 6 weeks up to 1 year</a></p><p id="niceng157er13.appe.fig9"><a href="/books/NBK561418/figure/niceng157er13.appe.fig9/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig9" class="figpopup">Figure 10. Revision, 5 years</a></p><p id="niceng157er13.appe.fig10"><a href="/books/NBK561418/figure/niceng157er13.appe.fig10/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig10" class="figpopup">Figure 11. Dislocation, 5 years</a></p><p id="niceng157er13.appe.fig11"><a href="/books/NBK561418/figure/niceng157er13.appe.fig11/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig11" class="figpopup">Figure 12. Deep Infection</a></p><p id="niceng157er13.appe.fig12"><a href="/books/NBK561418/figure/niceng157er13.appe.fig12/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig12" class="figpopup">Figure 13. Deep Infection</a></p><p id="niceng157er13.appe.fig13"><a href="/books/NBK561418/figure/niceng157er13.appe.fig13/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig13" class="figpopup">Figure 14. Intraoperative complications - lateral femoral cutaneous nerve injury, 8 days</a></p><p id="niceng157er13.appe.fig14"><a href="/books/NBK561418/figure/niceng157er13.appe.fig14/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig14" class="figpopup">Figure 15. Intraoperative complications - hyperesthesia</a></p><p id="niceng157er13.appe.fig15"><a href="/books/NBK561418/figure/niceng157er13.appe.fig15/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig15" class="figpopup">Figure 16. Intraoperative complications - blood loss (ml)</a></p><p id="niceng157er13.appe.fig16"><a href="/books/NBK561418/figure/niceng157er13.appe.fig16/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig16" class="figpopup">Figure 17. Surgery time (minutes)</a></p><p id="niceng157er13.appe.fig17"><a href="/books/NBK561418/figure/niceng157er13.appe.fig17/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig17" class="figpopup">Figure 18. Length of stay (days)</a></p></div><div id="niceng157er13.appe.s2"><h4>E.2. Direct anterior vs posterior</h4><p id="niceng157er13.appe.fig18"><a href="/books/NBK561418/figure/niceng157er13.appe.fig18/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig18" class="figpopup">Figure 19. Quality of life, EQ-5D, HOOS (QOL subscale) high is good outcome, 6 weeks or earlier</a></p><p id="niceng157er13.appe.fig19"><a href="/books/NBK561418/figure/niceng157er13.appe.fig19/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig19" class="figpopup">Figure 20. Quality of life, EQ-5D, HOOS (QOL subscale) high is good outcome, later than 6 weeks up to 1 year</a></p><p id="niceng157er13.appe.fig20"><a href="/books/NBK561418/figure/niceng157er13.appe.fig20/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig20" class="figpopup">Figure 21. Quality of life, SF-12 scale, mental subscales, high is good outcome, later than 6 weeks or up to 1 year</a></p><p id="niceng157er13.appe.fig21"><a href="/books/NBK561418/figure/niceng157er13.appe.fig21/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig21" class="figpopup">Figure 22. Quality of life, SF-12 scale, physical subscales, high is good outcome, later than 6 weeks or up to 1 year</a></p><p id="niceng157er13.appe.fig22"><a href="/books/NBK561418/figure/niceng157er13.appe.fig22/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig22" class="figpopup">Figure 23. PROMs, WOMAC, 0-96, high is poor</a></p><p id="niceng157er13.appe.fig23"><a href="/books/NBK561418/figure/niceng157er13.appe.fig23/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig23" class="figpopup">Figure 24. PROMs, Oxford Hip Score, 0-48, high is good</a></p><p id="niceng157er13.appe.fig24"><a href="/books/NBK561418/figure/niceng157er13.appe.fig24/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig24" class="figpopup">Figure 25. PROMs, Harris Hip Score, 0-100, high is good</a></p><p id="niceng157er13.appe.fig25"><a href="/books/NBK561418/figure/niceng157er13.appe.fig25/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig25" class="figpopup">Figure 26. PROMs, HOOS score - symptoms subscale, high is good, 6 weeks or earlier</a></p><p id="niceng157er13.appe.fig26"><a href="/books/NBK561418/figure/niceng157er13.appe.fig26/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig26" class="figpopup">Figure 27. PROMs, HOOS score - symptoms subscale, high is good, later than 6 weeks or up to 1 year</a></p><p id="niceng157er13.appe.fig27"><a href="/books/NBK561418/figure/niceng157er13.appe.fig27/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig27" class="figpopup">Figure 28. PROMs, HOOS score - pain subscale, high is good, later than 6 weeks or up to 1 year</a></p><p id="niceng157er13.appe.fig28"><a href="/books/NBK561418/figure/niceng157er13.appe.fig28/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig28" class="figpopup">Figure 29. PROMs, HOOS Jr score, high is good, after at least 2 years</a></p><p id="niceng157er13.appe.fig29"><a href="/books/NBK561418/figure/niceng157er13.appe.fig29/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig29" class="figpopup">Figure 30. PROMs, UCLA score, 6 months, high is poor</a></p><p id="niceng157er13.appe.fig30"><a href="/books/NBK561418/figure/niceng157er13.appe.fig30/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig30" class="figpopup">Figure 31. PROMs, UCLA score, after at least 2 years, high is good</a></p><p id="niceng157er13.appe.fig31"><a href="/books/NBK561418/figure/niceng157er13.appe.fig31/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig31" class="figpopup">Figure 32. Revision, 12 months</a></p><p id="niceng157er13.appe.fig32"><a href="/books/NBK561418/figure/niceng157er13.appe.fig32/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig32" class="figpopup">Figure 33. Dislocation, 12 months</a></p><p id="niceng157er13.appe.fig33"><a href="/books/NBK561418/figure/niceng157er13.appe.fig33/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig33" class="figpopup">Figure 34. Deep Infection, 6 weeks</a></p><p id="niceng157er13.appe.fig34"><a href="/books/NBK561418/figure/niceng157er13.appe.fig34/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig34" class="figpopup">Figure 35. Intraoperative complications - lateral cutaneous nerve of the thigh neuropraxia, 12 weeks</a></p><p id="niceng157er13.appe.fig35"><a href="/books/NBK561418/figure/niceng157er13.appe.fig35/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig35" class="figpopup">Figure 36. Intraoperative complications - blood loss (ml)</a></p><p id="niceng157er13.appe.fig36"><a href="/books/NBK561418/figure/niceng157er13.appe.fig36/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig36" class="figpopup">Figure 37. Length of stay (days)</a></p><p id="niceng157er13.appe.fig37"><a href="/books/NBK561418/figure/niceng157er13.appe.fig37/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig37" class="figpopup">Figure 38. Surgery time (minutes)</a></p></div><div id="niceng157er13.appe.s3"><h4>E.3. Posterior vs anterolateral</h4><p id="niceng157er13.appe.fig38"><a href="/books/NBK561418/figure/niceng157er13.appe.fig38/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig38" class="figpopup">Figure 39. PROMs, Harris Hip Score, 0-100, high is good</a></p><p id="niceng157er13.appe.fig39"><a href="/books/NBK561418/figure/niceng157er13.appe.fig39/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig39" class="figpopup">Figure 40. Revision, 37.9 months</a></p><p id="niceng157er13.appe.fig40"><a href="/books/NBK561418/figure/niceng157er13.appe.fig40/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig40" class="figpopup">Figure 41. Dislocation, 37.9 months</a></p><p id="niceng157er13.appe.fig41"><a href="/books/NBK561418/figure/niceng157er13.appe.fig41/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig41" class="figpopup">Figure 42. Reoperation, 6 months</a></p><p id="niceng157er13.appe.fig42"><a href="/books/NBK561418/figure/niceng157er13.appe.fig42/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig42" class="figpopup">Figure 43. Superficial surgical site infection, 12 weeks</a></p><p id="niceng157er13.appe.fig43"><a href="/books/NBK561418/figure/niceng157er13.appe.fig43/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig43" class="figpopup">Figure 44. Intraoperative complications - blood loss (ml)</a></p><p id="niceng157er13.appe.fig44"><a href="/books/NBK561418/figure/niceng157er13.appe.fig44/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig44" class="figpopup">Figure 45. Surgery time (minutes)</a></p><p id="niceng157er13.appe.fig45"><a href="/books/NBK561418/figure/niceng157er13.appe.fig45/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig45" class="figpopup">Figure 46. Pain later than 6 weeks up to 1 year, VAS scale, high is poor outcome (change score)</a></p></div><div id="niceng157er13.appe.s4"><h4>E.4. SuperPATH vs posterior</h4><p id="niceng157er13.appe.fig46"><a href="/books/NBK561418/figure/niceng157er13.appe.fig46/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig46" class="figpopup">Figure 47. PROMs, Barthel Index score, high is good</a></p><p id="niceng157er13.appe.fig47"><a href="/books/NBK561418/figure/niceng157er13.appe.fig47/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig47" class="figpopup">Figure 48. PROMs, Harris Hip Score, high is good</a></p><p id="niceng157er13.appe.fig48"><a href="/books/NBK561418/figure/niceng157er13.appe.fig48/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig48" class="figpopup">Figure 49. Dislocation, 12 months</a></p><p id="niceng157er13.appe.fig49"><a href="/books/NBK561418/figure/niceng157er13.appe.fig49/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig49" class="figpopup">Figure 50. Length of stay (days)</a></p><p id="niceng157er13.appe.fig50"><a href="/books/NBK561418/figure/niceng157er13.appe.fig50/?report=objectonly" target="object" rid-ob="figobniceng157er13appefig50" class="figpopup">Figure 51. Surgery time (minutes)</a></p></div></div><div id="niceng157er13.appf"><h3>Appendix F. GRADE tables</h3><p id="niceng157er13.appf.tab1"><a href="/books/NBK561418/table/niceng157er13.appf.tab1/?report=objectonly" target="object" rid-ob="figobniceng157er13appftab1" class="figpopup">Table 13. Clinical evidence profile: Direct anterior approach versus Anterolateral approach</a></p><p id="niceng157er13.appf.tab2"><a href="/books/NBK561418/table/niceng157er13.appf.tab2/?report=objectonly" target="object" rid-ob="figobniceng157er13appftab2" class="figpopup">Table 14. Clinical evidence profile: Direct anterior approach versus Posterior approach</a></p><p id="niceng157er13.appf.tab3"><a href="/books/NBK561418/table/niceng157er13.appf.tab3/?report=objectonly" target="object" rid-ob="figobniceng157er13appftab3" class="figpopup">Table 15. Clinical evidence profile: Anterolateral approach versus Posterior approach</a></p><p id="niceng157er13.appf.tab4"><a href="/books/NBK561418/table/niceng157er13.appf.tab4/?report=objectonly" target="object" rid-ob="figobniceng157er13appftab4" class="figpopup">Table 16. Clinical evidence profile: SuperPATH approach versus Posterior approach</a></p></div><div id="niceng157er13.appg"><h3>Appendix G. Health economic evidence selection</h3><p id="niceng157er13.appg.fig1"><a href="/books/NBK561418/figure/niceng157er13.appg.fig1/?report=objectonly" target="object" rid-ob="figobniceng157er13appgfig1" class="figpopup">Figure 52. Flow chart of health economic study selection for the guideline</a></p></div><div id="niceng157er13.apph"><h3>Appendix H. Health economic evidence tables</h3><p id="niceng157er13.apph.et1"><a href="/books/NBK561418/bin/niceng157er13-apph-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Download PDF</a><span class="small"> (187K)</span></p></div><div id="niceng157er13.appi"><h3>Appendix I. Excluded studies</h3><div id="niceng157er13.appi.s1"><h4>I.1. Excluded clinical studies</h4><p id="niceng157er13.appi.tab1"><a href="/books/NBK561418/table/niceng157er13.appi.tab1/?report=objectonly" target="object" rid-ob="figobniceng157er13appitab1" class="figpopup">Table 17. Studies excluded from the clinical review</a></p></div><div id="niceng157er13.appi.s2"><h4>I.2. Excluded health economic studies</h4><p>Studies that meet the review protocol population and interventions, and the economic study inclusion criteria but have not been included in the review based on applicability and/or methodological quality are summarised below with reasons for exclusion.</p><p id="niceng157er13.appi.tab2"><a href="/books/NBK561418/table/niceng157er13.appi.tab2/?report=objectonly" target="object" rid-ob="figobniceng157er13appitab2" class="figpopup">Table 18. Studies excluded from the health economic review</a></p></div></div><div id="niceng157er13.appj"><h3>Appendix J. Research recommendations</h3><div id="niceng157er13.appj.s1"><h4>J.1. Surgical approaches in primary elective hip replacement</h4><p>
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<b>Research question: Do the direct anterior, direct superior and supercapsular percutaneously assisted(SuperPATH) approaches to hip replacement improve patient-recorded outcome measures and reduce length of hospital stays, revision rates, neurological complications and surgical site infections compared with the posterior and anterolateral approaches?</b>
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</p><p>
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<b>Why this is important:</b>
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</p><p>The posterior and anterolateral approaches to the hip and the most commonly used approaches for hip replacement surgery. In 2017 NJR data reported that 93,161 of 96,717 (96.3%) of primary hip replacements were performed through one of these two approaches.<a class="bibr" href="#niceng157er13.ref73" rid="niceng157er13.ref73"><sup>73</sup></a> Hip replacements undertaken through these two approaches have excellent results with low 10 year failure rates, significant improvement in functional outcome scores and low rates of complications. In recent years there has been increased uptake and interest in alternative hip approaches (direct anterior, direct superior, superPATH). These approaches have theoretical advantages but often require additional specialist equipment and surgery can take longer to perform, both of which may have cost implications. Furthermore the NICE evidence review raised concerns about the rates of specific complications with some of these newer approaches. There is currently no evidence to support the wider adoption of these approaches and this research recommendation had therefore been developed to support specific research in this area.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figniceng157er13appjtab1"><a href="/books/NBK561418/table/niceng157er13.appj.tab1/?report=objectonly" target="object" title="Table" class="img_link icnblk_img figpopup" rid-figpopup="figniceng157er13appjtab1" rid-ob="figobniceng157er13appjtab1"><img class="small-thumb" src="/books/NBK561418/table/niceng157er13.appj.tab1/?report=thumb" src-large="/books/NBK561418/table/niceng157er13.appj.tab1/?report=previmg" alt="Image " /></a><div class="icnblk_cntnt"><h4 id="niceng157er13.appj.tab1"><a href="/books/NBK561418/table/niceng157er13.appj.tab1/?report=objectonly" target="object" rid-ob="figobniceng157er13appjtab1">Table</a></h4><p class="float-caption no_bottom_margin">Population: Patients receiving an elective primary total hip replacement Intervention(s): Direct anterior, direct superior or superPATH surgical approaches to the hip</p></div></div></div></div></div></div><div class="fm-sec"><div><p>Final</p></div><div><p>Intervention evidence review underpinning recommendation 1.8.1 and the research recommendation in the NICE guideline</p><p>This evidence review was developed by the National Guideline Centre, hosted by the Royal College of Physicians</p></div><div><p><b>Disclaimer:</b> The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The recommendations in this guideline are not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and, where appropriate, their carer or guardian.</p><p>Local commissioners and providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties.</p><p>NICE guidelines cover health and care in England. Decisions on how they apply in other UK countries are made by ministers in the <a href="http://wales.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Welsh Government</a>, <a href="http://www.scotland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Scottish Government</a>, and <a href="http://www.northernireland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Northern Ireland Executive</a>. All NICE guidance is subject to regular review and may be updated or withdrawn.</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> © NICE 2020.</div><div class="small"><span class="label">Bookshelf ID: NBK561418</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32881466" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">32881466</a></span></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article><article data-type="table-wrap" id="figobniceng157er13tab1"><div id="niceng157er13.tab1" class="table"><h3><span class="label">Table 1</span><span class="title">PICO characteristics of review question</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab1_lrgtbl__"><table><tbody><tr><th id="hd_b_niceng157er13.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><td headers="hd_b_niceng157er13.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adults indicated for primary total hip replacement</td></tr><tr><th id="hd_b_niceng157er13.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intervention(s)</th><td headers="hd_b_niceng157er13.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul><li class="half_rhythm"><div>Primary total hip replacement utilising the posterior approach</div></li><li class="half_rhythm"><div>Primary total hip replacement utilising the direct anterior approach</div></li><li class="half_rhythm"><div>Primary total hip replacement utilising the anterolateral approach</div></li><li class="half_rhythm"><div>Primary total hip replacement utilising the SuperPATH approach</div></li><li class="half_rhythm"><div>Primary total hip replacement utilising the direct superior approach</div></li></ul></td></tr><tr><th id="hd_b_niceng157er13.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Comparison</th><td headers="hd_b_niceng157er13.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Comparison between interventions</td></tr><tr><th id="hd_b_niceng157er13.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes</th><td headers="hd_b_niceng157er13.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><b>Critical</b>
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<ul><li class="half_rhythm"><div>Mortality: life expectancy</div></li><li class="half_rhythm"><div>Mortality: 30 day</div></li><li class="half_rhythm"><div>Quality of life at 6 weeks or earlier, later than 6 weeks up to 1 year, at least 2 years</div></li><li class="half_rhythm"><div>Patient Reported Outcome Measures (PROMs) at 6 weeks or earlier, later than 6 weeks up to 1 year, at least 2 years</div></li><li class="half_rhythm"><div>Revision rate of joint replacement</div></li></ul>
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<b>Important</b>
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<ul><li class="half_rhythm"><div>Deep surgical site infection</div></li><li class="half_rhythm"><div>Superficial surgical site infection</div></li><li class="half_rhythm"><div>Length of stay</div></li><li class="half_rhythm"><div>Reoperation/dislocation rate</div></li><li class="half_rhythm"><div>Intraoperative complications (for example nerve damage)</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul>
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To be extracted when not included within a PROM:
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<ul><li class="half_rhythm"><div>Function at 6 weeks or earlier, later than 6 weeks up to 1 year, at least 2 years</div></li><li class="half_rhythm"><div>Pain at 6 weeks or earlier, later than 6 weeks up to 1 year, at least 2 years</div></li></ul></td></tr><tr><th id="hd_b_niceng157er13.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study design</th><td headers="hd_b_niceng157er13.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>Randomised controlled trials</p><p>If no well conducted RCTs are available then observational studies with multivariate analysis will be investigated.</p></td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13tab2"><div id="niceng157er13.tab2" class="table"><h3><span class="label">Table 2</span><span class="title">Summary of studies included in the evidence review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab2_lrgtbl__"><table><thead><tr><th id="hd_h_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_niceng157er13.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intervention and comparison</th><th id="hd_h_niceng157er13.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><th id="hd_h_niceng157er13.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes</th><th id="hd_h_niceng157er13.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Comments</th></tr></thead><tbody><tr><th headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_h_niceng157er13.tab2_1_1_1_2 hd_h_niceng157er13.tab2_1_1_1_3 hd_h_niceng157er13.tab2_1_1_1_4 hd_h_niceng157er13.tab2_1_1_1_5" id="hd_b_niceng157er13.tab2_1_1_1_1" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Direct anterior approach versus anterolateral approach</th></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Brismar 2018<a class="bibr" href="#niceng157er13.ref9" rid="niceng157er13.ref9"><sup>9</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Direct anterior approach (n=50)</p>
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<p>Versus</p>
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<p>Anterolateral approach (n=50)</p>
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</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
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<p>Median (IQR) age:</p>
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<p>Anterior – 66 years (58 to 74)</p>
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<p>Anterolateral - 67 years (60 to 76)</p>
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</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
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<ul><li class="half_rhythm"><div>Pain</div></li></ul>
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After at least 2 years:
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<ul><li class="half_rhythm"><div>Dislocation</div></li><li class="half_rhythm"><div>Revision</div></li><li class="half_rhythm"><div>Intraoperative complications</div></li><li class="half_rhythm"><div>Deep surgical site infection</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sweden</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">D’arrigo 2009<a class="bibr" href="#niceng157er13.ref15" rid="niceng157er13.ref15"><sup>15</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior (anterior tissue sparing) approach (n=20)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (modified Hardinge anterolateral) approach (n=20)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (anterolateral tissue sparing) approach (n=20)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 64 years (8)</p>
|
|
<p>Anterolateral – 66.3 years (10.4)</p>
|
|
<p>Anterolateral (TSS) – 66 years (7.5)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">WOMAC scale</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Intraoperative complications</div></li><li class="half_rhythm"><div>Length of stay</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Italy</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">De anta-diaz 2016<a class="bibr" href="#niceng157er13.ref16" rid="niceng157er13.ref16"><sup>16</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Anterolateral (direct lateral) approach (n=50)</p>
|
|
<p>Versus</p>
|
|
<p>Direct Anterior approach (n=49)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Lateral - 63.5 years (12.5)</p>
|
|
<p>Anterior - 64.8 years (10.1)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Spain</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mayr 2009<a class="bibr" href="#niceng157er13.ref56" rid="niceng157er13.ref56"><sup>56</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=16)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral approach (n=17)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (range) age:</p>
|
|
<p>Lateral – 69 years (59 to 78)</p>
|
|
<p>Anterior - 65 years (55 to 84)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No usable outcomes</td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Austria</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mjaaland 2015<a class="bibr" href="#niceng157er13.ref64" rid="niceng157er13.ref64"><sup>64</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=84)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (direct lateral) approach (n=80)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 67.2 years (8.6)</p>
|
|
<p>Lateral – 65.6 years (8.6)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier:
|
|
<ul><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Norway</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nistor 2017<a class="bibr" href="#niceng157er13.ref74" rid="niceng157er13.ref74"><sup>74</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=35)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (direct lateral) approach (n=35)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Median (IQR) age:</p>
|
|
<p>Anterior – 67 years (53.5 to 72.5)</p>
|
|
<p>Lateral – 64 years (54.4 to 67.5)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier:
|
|
<ul><li class="half_rhythm"><div>Deep surgical site infection</div></li><li class="half_rhythm"><div>Intraoperative complications</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Romania</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Parvizi 2016<a class="bibr" href="#niceng157er13.ref81" rid="niceng157er13.ref81"><sup>81</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=44)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (direct lateral) approach (n=40)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>No age details given</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No usable outcomes</td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">USA</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reichert 2018<a class="bibr" href="#niceng157er13.ref87" rid="niceng157er13.ref87"><sup>87</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=77)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (direct transgluteal lateral) approach (n=71)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 63.2 years (8.2)</p>
|
|
<p>Lateral – 61.9 years (7.8)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier and later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>Quality of life
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">SF-36 scale</p></dd></dl></dl></div></li><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Dislocation</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Germany</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Restrepo 2010<a class="bibr" href="#niceng157er13.ref90" rid="niceng157er13.ref90"><sup>90</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=63)</p>
|
|
<p>Versus</p>
|
|
<p>Direct lateral approach (n=59)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (range) age:</p>
|
|
<p>Anterior – 62.02 years (35 to 84.5)</p>
|
|
<p>Lateral – 59.91 years (40.1 to 76.1)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No usable outcomes</td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">USA</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Zomar 2018<a class="bibr" href="#niceng157er13.ref130" rid="niceng157er13.ref130"><sup>130</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct lateral approach (n=42)</p>
|
|
<p>Versus</p>
|
|
<p>Direct anterior approach (n=36)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 59.54 years (8.40)</p>
|
|
<p>Lateral – 60.78 years (9.26)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier and later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">WOMAC scale</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Quality of life
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">SF-12 scale</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Length of stay</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Canada</td></tr><tr><th headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_h_niceng157er13.tab2_1_1_1_2 hd_h_niceng157er13.tab2_1_1_1_3 hd_h_niceng157er13.tab2_1_1_1_4 hd_h_niceng157er13.tab2_1_1_1_5" id="hd_b_niceng157er13.tab2_1_1_12_1" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Direct anterior approach versus posterior approach</th></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Barrett 2013<a class="bibr" href="#niceng157er13.ref2" rid="niceng157er13.ref2"><sup>2</sup></a></p>
|
|
<p>Barrett 2019<a class="bibr" href="#niceng157er13.ref3" rid="niceng157er13.ref3"><sup>3</sup></a></p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=43)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior approach (n=44)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 61.4 years (9.2)</p>
|
|
<p>Posterior – 63.2 years (7.7)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier and later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Hip disability and arthritis outcome score</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">UCLA score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Revisions</div></li><li class="half_rhythm"><div>Dislocation</div></li><li class="half_rhythm"><div>Length of stay</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">USA</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Cheng 2017<a class="bibr" href="#niceng157er13.ref12" rid="niceng157er13.ref12"><sup>12</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=37)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior approach (n=38)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Median (IQR) age:</p>
|
|
<p>Anterior – 59 years (54 to 69)</p>
|
|
<p>Posterior – 62.5 years (55 to 69)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier and later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>Quality of life
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">EQ-5D</p></dd></dl></dl></div></li><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">WOMAC</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Oxford hip score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Revisions</div></li><li class="half_rhythm"><div>Dislocations</div></li><li class="half_rhythm"><div>Intraoperative complications</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Australia</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Christensen 2015<a class="bibr" href="#niceng157er13.ref13" rid="niceng157er13.ref13"><sup>13</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=32)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior approach (n=24)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 64.3 years (9.1)</p>
|
|
<p>Posterior – 65.2 years (9.1)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Length of stay</td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">USA</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reininga 2013<a class="bibr" href="#niceng157er13.ref88" rid="niceng157er13.ref88"><sup>88</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Posterior (posterolateral) approach (n=40)</p>
|
|
<p>Versus</p>
|
|
<p>Direct anterior (minimally invasive anterior) approach (=35)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 60.3 years (7.7)</p>
|
|
<p>Posterior – 60.5 years (9.5)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No usable outcomes</td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Netherlands</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rykov 2017<a class="bibr" href="#niceng157er13.ref97" rid="niceng157er13.ref97"><sup>97</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=23)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior (posterolateral) approach (n=23)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 62.8 years (6.1)</p>
|
|
<p>Posterior – 60.2 years (8.1)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">At 6 weeks or earlier:
|
|
<ul><li class="half_rhythm"><div>Deep surgical site infection</div></li><li class="half_rhythm"><div>Length of stay</div></li><li class="half_rhythm"><div>Intraoperative complications</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Netherlands</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Taunton 2014<a class="bibr" href="#niceng157er13.ref108" rid="niceng157er13.ref108"><sup>108</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=27)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior (mini-posterior) approach (n=27)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean age:</p>
|
|
<p>Anterior – 62.05 years</p>
|
|
<p>Posterior – 66.4 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Later than 6 weeks up to 1 year:</p>
|
|
<p>Function</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">USA</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Taunton 2018<a class="bibr" href="#niceng157er13.ref109" rid="niceng157er13.ref109"><sup>109</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=56)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior (mini-posterior) approach (n=60)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 65 years (10)</p>
|
|
<p>Mini-posterior – 64 years (11)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>Quality of life
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">SF-12</p></dd></dl></dl></div></li><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">HOOS score</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris Hip score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Dislocation</div></li><li class="half_rhythm"><div>Length of stay</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">USA</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Zhao 2017<a class="bibr" href="#niceng157er13.ref128" rid="niceng157er13.ref128"><sup>128</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Direct anterior approach (n=64)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior (posterolateral) approach (n=64)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Anterior – 64.88 years (12.13)</p>
|
|
<p>Posterior – 62.18 years (14.72)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">UCLA score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Length of stay</div></li><li class="half_rhythm"><div>Intraoperative complications</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_12_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">China</td></tr><tr><th headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_h_niceng157er13.tab2_1_1_1_2 hd_h_niceng157er13.tab2_1_1_1_3 hd_h_niceng157er13.tab2_1_1_1_4 hd_h_niceng157er13.tab2_1_1_1_5" id="hd_b_niceng157er13.tab2_1_1_21_1" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Posterior approach versus anterolateral approach</th></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Catma 2017<a class="bibr" href="#niceng157er13.ref10" rid="niceng157er13.ref10"><sup>10</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Posterior approach (n=34)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral approach (n=34)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age: 51.1 years (9.4)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Dislocation</div></li><li class="half_rhythm"><div>Reoperation</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Turkey</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ji 2012<a class="bibr" href="#niceng157er13.ref41" rid="niceng157er13.ref41"><sup>41</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Posterior approach (n=105)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (modified lateral) approach (n=100)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD) age:</p>
|
|
<p>Posterior – 51 years (14.5)</p>
|
|
<p>Lateral – 52 years (15.1)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">After at least 2 years:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Revision</div></li><li class="half_rhythm"><div>Dislocation</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">South Korea</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lorenzen 2013<a class="bibr" href="#niceng157er13.ref52" rid="niceng157er13.ref52"><sup>52</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Posterior approach (n=18)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral approach (n=20)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (range):</p>
|
|
<p>Posterior – 45 years (36 to 60)</p>
|
|
<p>Lateral – 53 years (35 to 61)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>Pain</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Denmark</p>
|
|
<p>This is the same RCT as Tjur, 2018<a class="bibr" href="#niceng157er13.ref110" rid="niceng157er13.ref110"><sup>110</sup></a></p>
|
|
<p>People in this study meet the working age subgroup.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meneghini 2008<a class="bibr" href="#niceng157er13.ref59" rid="niceng157er13.ref59"><sup>59</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Posterior (mini posterior) approach (n=8)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (mini-anterolateral) approach (n=7)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (range) age:</p>
|
|
<p>54 years (38 to 74)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No usable outcomes</td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">USA</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rosenlund 2016<a class="bibr" href="#niceng157er13.ref95" rid="niceng157er13.ref95"><sup>95</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Posterior approach (n=23)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (direct lateral) approach (n=24)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD):</p>
|
|
<p>Posterior – 61 years (6.7)</p>
|
|
<p>Lateral – 60.5 years (6.6)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>Revision</div></li><li class="half_rhythm"><div>Dislocation</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Denmark</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Witzleb 2009<a class="bibr" href="#niceng157er13.ref115" rid="niceng157er13.ref115"><sup>115</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Posterior approach (n=30)</p>
|
|
<p>Versus</p>
|
|
<p>Anterolateral (direct lateral) approach (n=30)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Median (range):</p>
|
|
<p>Posterior – 55 years (47 to 64)</p>
|
|
<p>Lateral – 58 years (46 to 64)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>Superficial surgical site infection</div></li><li class="half_rhythm"><div>Dislocations</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Germany</p>
|
|
<p>People in this study meet the working age subgroup.</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Yang 2010<a class="bibr" href="#niceng157er13.ref124" rid="niceng157er13.ref124"><sup>124</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Anterolateral approach (n=55)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior (postlateral) approach (n=55)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD):</p>
|
|
<p>Posterior – 55.82 years (13.91)</p>
|
|
<p>Lateral – 59.47 years (13.24)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">After at least 2 years::
|
|
<ul><li class="half_rhythm"><div>Intraoperative complications</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">China</td></tr><tr><th headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_h_niceng157er13.tab2_1_1_1_2 hd_h_niceng157er13.tab2_1_1_1_3 hd_h_niceng157er13.tab2_1_1_1_4 hd_h_niceng157er13.tab2_1_1_1_5" id="hd_b_niceng157er13.tab2_1_1_29_1" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">SuperPATH approach versus posterior approach</th></tr><tr><td headers="hd_h_niceng157er13.tab2_1_1_1_1 hd_b_niceng157er13.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Xie 2017<a class="bibr" href="#niceng157er13.ref118" rid="niceng157er13.ref118"><sup>118</sup></a></td><td headers="hd_h_niceng157er13.tab2_1_1_1_2 hd_b_niceng157er13.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Super path approach (n=46)</p>
|
|
<p>Versus</p>
|
|
<p>Posterior approach (n=46)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_3 hd_b_niceng157er13.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Adults with hip osteoarthritis indicated for primary total hip replacement</p>
|
|
<p>Mean (SD):</p>
|
|
<p>SuperPATH – 66.60 years (11.88)</p>
|
|
<p>Posterior – 64.47 years (12.09)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab2_1_1_1_4 hd_b_niceng157er13.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Later than 6 weeks up to 1 year:
|
|
<ul><li class="half_rhythm"><div>PROMs
|
|
<dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Harris hip score</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd><p class="no_top_margin">Barthel index score</p></dd></dl></dl></div></li><li class="half_rhythm"><div>Length of stay</div></li><li class="half_rhythm"><div>Dislocation</div></li><li class="half_rhythm"><div>Surgery time</div></li></ul></td><td headers="hd_h_niceng157er13.tab2_1_1_1_5 hd_b_niceng157er13.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">China</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13tab3"><div id="niceng157er13.tab3" class="table"><h3><span class="label">Table 3</span><span class="title">Clinical evidence summary: Direct anterior approach versus anterolateral approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab3_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab3_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab3_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab3_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab3_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_niceng157er13.tab3_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_niceng157er13.tab3_1_1_1_5" id="hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Anterolateral approach</th><th headers="hd_h_niceng157er13.tab3_1_1_1_5" id="hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Direct anterior (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mortality</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2 hd_h_niceng157er13.tab3_1_1_1_3 hd_h_niceng157er13.tab3_1_1_1_4 hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1 hd_h_niceng157er13.tab3_1_1_2_2" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Mortality</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life at 6 weeks or earlier</p>
|
|
<p>SF-12, SF-36 - mental subscale</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>226</p>
|
|
<p>(2 studies)</p>
|
|
<p>2 to 6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>56.70</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>0.15 standard deviations lower</p>
|
|
<p>(0.42 lower to 0.11 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life at 6 weeks or earlier</p>
|
|
<p>SF-12, SF-36 - physical subscale</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>226</p>
|
|
<p>(2 studies)</p>
|
|
<p>2 to 6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>32.59</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>2.67 higher</p>
|
|
<p>(0.34 to 5.01 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life later than 6 weeks up to 1 year</p>
|
|
<p>SF-12, SF-36 - mental subscale</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>226</p>
|
|
<p>(2 studies)</p>
|
|
<p>3 to 12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>56.01</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>1.01 lower</p>
|
|
<p>(3.20 lower to 1.18 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life later than 6 weeks up to 1 year</p>
|
|
<p>SF-12, SF-36 - physical subscale</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>226</p>
|
|
<p>(2 studies)</p>
|
|
<p>3 to 12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup><sup>,</sup><sup>3</sup></p>
|
|
<p>due to risk of bias, inconsistency, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>44.79</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>1.96 higher</p>
|
|
<p>(3.28 lower to 7.21 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs at 6 weeks or earlier</p>
|
|
<p>WOMAC - total score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>138</p>
|
|
<p>(3 studies)</p>
|
|
<p>6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>28</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>3.75 lower</p>
|
|
<p>(7.77 to 0.27 lower)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs at 6 weeks or earlier</p>
|
|
<p>Harris Hip Score. Scale from: 0 to 100.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>208</p>
|
|
<p>(3 studies)</p>
|
|
<p>6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>88.3</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>0.49 higher</p>
|
|
<p>(2.35 lower to 3.33 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>WOMAC - total score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>78</p>
|
|
<p>(1 study)</p>
|
|
<p>3 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>84.35</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>3.01 lower</p>
|
|
<p>(8.34 lower to 2.32 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>Harris Hip Score. Scale from: 0 to 100.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>325</p>
|
|
<p>(3 studies)</p>
|
|
<p>3 to 12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>92.04</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>1.95 higher</p>
|
|
<p>(0.07 to 3.84 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Revision later than 2 years</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>87</p>
|
|
<p>(1 study)</p>
|
|
<p>5 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 6.91</p>
|
|
<p>(0.14 to 349.18)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">0 per 1000</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>20 more per 1000</p>
|
|
<p>(from 40 fewer to 80 more)<sup>5</sup></p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dislocation later than 2 years</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>235</p>
|
|
<p>(2 studies)</p>
|
|
<p>1 to 5 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup><sup>,</sup><sup>4</sup></p>
|
|
<p>due to risk of bias, imprecision, indirectness</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 3.2</p>
|
|
<p>(0.54 to 18.95)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9 per 1000</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>20 more per 1000</p>
|
|
<p>(from 20 fewer to 70 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Deep Infection at 6 weeks or earlier</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>70</p>
|
|
<p>(1 study)</p>
|
|
<p>8 days</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>RR 0.50</p>
|
|
<p>(0.05 to 5.27)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57 per 1000</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>29 fewer per 1000</p>
|
|
<p>(from 54 fewer to 244 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Deep Infection later than 2 years</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>87</p>
|
|
<p>(1 study)</p>
|
|
<p>5 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 6.91</p>
|
|
<p>(0.14 to 349.18)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">0 per 1000</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>20 more per 1000</p>
|
|
<p>(from 40 fewer to 80 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - lateral femoral cutaneous nerve injury, at 6 weeks or earlier</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>70</p>
|
|
<p>(1 study)</p>
|
|
<p>8 days</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 7.61</p>
|
|
<p>(0.47 to 124.15)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">0 per 1000</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>60 more per 1000</p>
|
|
<p>(from 30 fewer to 150 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications – hyperesthesia, later than 2 years</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>87</p>
|
|
<p>(1 study)</p>
|
|
<p>5 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 0.13</p>
|
|
<p>(0 to 6.37)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24 per 1000</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>20 fewer per 1000</p>
|
|
<p>(from 90 fewer to 40 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications – blood loss (ml) at 6 weeks or earlier</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>60</p>
|
|
<p>(2 studies)</p>
|
|
<p>6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean intraoperative complications - blood loss</p>
|
|
<p>(ml) in the control groups was</p>
|
|
<p>1249</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean intraoperative complications - blood loss (ml) in the intervention groups was</p>
|
|
<p>93.69 higher</p>
|
|
<p>(292.87 lower to 480.26 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes)</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>323</p>
|
|
<p>(4 studies)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup><sup>,</sup><sup>3</sup></p>
|
|
<p>due to risk of bias, inconsistency, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean surgery time (minutes) in the control groups was</p>
|
|
<p>92.1</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean surgery time (minutes) in the intervention groups was</p>
|
|
<p>9.57 higher</p>
|
|
<p>(2.60 lower to 21.74 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Length of stay (days)</td><td headers="hd_h_niceng157er13.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>138</p>
|
|
<p>(3 studies)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup><sup>,</sup><sup>3</sup></p>
|
|
<p>due to risk of bias, inconsistency, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean length of stay (days) in the control groups was</p>
|
|
<p>7.07</p>
|
|
</td><td headers="hd_h_niceng157er13.tab3_1_1_1_5 hd_h_niceng157er13.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean length of stay (days) in the intervention groups was</p>
|
|
<p>0.79 standard deviations lower</p>
|
|
<p>(1.66 lower to 0.07 higher)</p>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.tab3_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.tab3_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl><dl class="bkr_refwrap"><dt>3</dt><dd><div id="niceng157er13.tab3_3"><p class="no_margin">Downgraded by 1 or 2 increments because the point estimates varied widely across studies, unexplained by subgroup analysis. Random effects model utilised.</p></div></dd></dl><dl class="bkr_refwrap"><dt>4</dt><dd><div id="niceng157er13.tab3_4"><p class="no_margin">Downgraded by 1 or 2 increments because the meta-analysed time points vary slightly from the protocol.</p></div></dd></dl><dl class="bkr_refwrap"><dt>5</dt><dd><div id="niceng157er13.tab3_5"><p class="no_margin">Absolute values calculated using the risk difference.</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13tab4"><div id="niceng157er13.tab4" class="table"><h3><span class="label">Table 4</span><span class="title">Clinical evidence summary: Direct anterior approach versus posterior approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab4_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab4_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab4_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab4_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab4_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_niceng157er13.tab4_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_niceng157er13.tab4_1_1_1_5" id="hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Posterior approach</th><th headers="hd_h_niceng157er13.tab4_1_1_1_5" id="hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Direct anterior (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mortality</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2 hd_h_niceng157er13.tab4_1_1_1_3 hd_h_niceng157er13.tab4_1_1_1_4 hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1 hd_h_niceng157er13.tab4_1_1_2_2" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Not reported</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life at 6 weeks or earlier</p>
|
|
<p>EQ-5D, HOOS (QOL subscale)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>160</p>
|
|
<p>(2 studies)</p>
|
|
<p>2 to 6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>31.6</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>0.40 standard deviations lower</p>
|
|
<p>(0.71 to 0.08 lower)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life later than 6 weeks up to 1 year</p>
|
|
<p>EQ-5D, HOOS (QOL subscale)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>261</p>
|
|
<p>(3 studies)</p>
|
|
<p>3 to 12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>47.73</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>0.03 standard deviations lower</p>
|
|
<p>(0.28 lower to 0.21 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life later than 6 weeks up to 1 year</p>
|
|
<p>SF-12 scale mental subscale</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>101</p>
|
|
<p>(1 study)</p>
|
|
<p>1 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>54</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>0.00 higher</p>
|
|
<p>(2.21 lower to 2.21 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Quality of life later than 6 weeks up to 1 year</p>
|
|
<p>SF-12 scale physical subscale</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>101</p>
|
|
<p>(1 study)</p>
|
|
<p>1 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the control groups was</p>
|
|
<p>49</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean quality of life in the intervention groups was</p>
|
|
<p>1.00 higher</p>
|
|
<p>(2.35 lower to 4.35 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs at 6 weeks or earlier</p>
|
|
<p>WOMAC scale. Scale from: 0 to 96.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>73</p>
|
|
<p>(1 study)</p>
|
|
<p>2 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>40.3</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>4.2 higher</p>
|
|
<p>(4.1 lower to 12.5 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>WOMAC scale. Scale from: 0 to 96.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>73</p>
|
|
<p>(1 study)</p>
|
|
<p>12 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>9.1</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>3.7 higher</p>
|
|
<p>(1.98 lower to 9.38 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs at 6 weeks or earlier</p>
|
|
<p>Oxford Hip Score. Scale from: 0 to 48.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>73</p>
|
|
<p>(1 study)</p>
|
|
<p>2 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>28.5</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>1.7 lower</p>
|
|
<p>(6.01 lower to 2.61 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>Oxford Hip Score. Scale from: 0 to 48.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>73</p>
|
|
<p>(1 study)</p>
|
|
<p>12 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>43.8</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>1 lower</p>
|
|
<p>(3.4 lower to 1.4 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs at 6 weeks or earlier</p>
|
|
<p>Harris Hip Total Score. Scale from: 0 to 100.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>87</p>
|
|
<p>(1 study)</p>
|
|
<p>6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>89.5</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>8.1 lower</p>
|
|
<p>(11.87 to 4.33 lower)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>Harris Hip Score. Scale from: 0 to 100.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>308</p>
|
|
<p>(3 studies)</p>
|
|
<p>6 to 12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>95.57</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>1.28 lower</p>
|
|
<p>(2.80 lower to 0.25 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs after at least 2 years</p>
|
|
<p>Harris Hip Score. Scale from: 0 to 100</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>79</p>
|
|
<p>(1 study)</p>
|
|
<p>5 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>96.9</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>0.20 higher</p>
|
|
<p>(3.87 lower to 4.27 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PROMs - Symptoms subscale HOOS score, at 6 weeks or earlier</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>87</p>
|
|
<p>(1 study)</p>
|
|
<p>6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms - symptoms subscale in the control groups was</p>
|
|
<p>79.4</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms - symptoms subscale in the intervention groups was</p>
|
|
<p>0.5 higher</p>
|
|
<p>(4.53 lower to 5.53 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PROMs - symptoms subscale HOOS score, later than 6 weeks up to 1 year</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>188</p>
|
|
<p>(2 studies)</p>
|
|
<p>12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms - symptoms subscale in the control groups was</p>
|
|
<p>80.95</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms - symptoms subscale in the intervention groups was</p>
|
|
<p>3.12 lower</p>
|
|
<p>(6.27 lower to 0.03 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>HOOS score - pain subscale</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>101</p>
|
|
<p>(1 study)</p>
|
|
<p>1 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>69</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>2.00 lower</p>
|
|
<p>(5.93 lower to 1.93 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs after at least 2 years</p>
|
|
<p>HOOS Jr Total Score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>78</p>
|
|
<p>(1 study)</p>
|
|
<p>6.2 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>95.7</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>2.80 lower</p>
|
|
<p>(7.84 lower to 2.24 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>UCLA score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>120</p>
|
|
<p>(1 study)</p>
|
|
<p>6 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>7.04</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>0.08 lower</p>
|
|
<p>(0.5 lower to 0.34 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs after at least 2 years</p>
|
|
<p>UCLA score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>75</p>
|
|
<p>(1 study)</p>
|
|
<p>5 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>6.33</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>0.07 lower</p>
|
|
<p>(0.87 lower to 0.73 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Revision later than 6 weeks up to 1 year</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>160</p>
|
|
<p>(2 studies)</p>
|
|
<p>12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 1.84</p>
|
|
<p>(0.19 to 17.91)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13 per 1000</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>10 more per 1000</p>
|
|
<p>(from 40 fewer to 60 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dislocation later than 6 weeks up to 1 year</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>261</p>
|
|
<p>(3 studies)</p>
|
|
<p>12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 1.48</p>
|
|
<p>(0.25 to 8.61)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15 per 1000</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>10 more per 1000</p>
|
|
<p>(from 30 fewer to 40 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Deep Infection at 6 weeks or earlier</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>46</p>
|
|
<p>(1 study)</p>
|
|
<p>6 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>2</sup></p>
|
|
<p>due to imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>RR 0.5</p>
|
|
<p>(0.05 to 5.14)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87 per 1000</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>43 fewer per 1000</p>
|
|
<p>(from 83 fewer to 360 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - lateral cutaneous nerve of the thigh neuropraxia, later than 6 weeks up to 1 year</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>73</p>
|
|
<p>(1 study)</p>
|
|
<p>12 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>MODERATE<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 0.03</p>
|
|
<p>(0.01 to 0.08)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">829 per 1000</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>830 fewer per 1000</p>
|
|
<p>(from 960 fewer to 700 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - blood loss (ml)</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>166</p>
|
|
<p>(2 studies)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean intraoperative complications - blood loss (ml) in the control groups was</p>
|
|
<p>245.795</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean intraoperative complications - blood loss (ml) in the intervention groups was</p>
|
|
<p>0.69 standard deviations lower</p>
|
|
<p>(1.01 to 0.38 lower)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Length of stay (days)</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>405</p>
|
|
<p>(5 studies)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean length of stay (days) in the control groups was</p>
|
|
<p>2.28</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean length of stay (days) in the intervention groups was</p>
|
|
<p>0.22 higher</p>
|
|
<p>(0.03 to 0.41 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes)</td><td headers="hd_h_niceng157er13.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>354</p>
|
|
<p>(4 studies)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup><sup>,</sup><sup>3</sup></p>
|
|
<p>due to risk of bias, inconsistency, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean surgery time (minutes) in the control groups was</p>
|
|
<p>77.13</p>
|
|
</td><td headers="hd_h_niceng157er13.tab4_1_1_1_5 hd_h_niceng157er13.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean surgery time (minutes) in the intervention groups was</p>
|
|
<p>14.98 lower</p>
|
|
<p>(21.77 to 8.20 lower)</p>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.tab4_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.tab4_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl><dl class="bkr_refwrap"><dt>3</dt><dd><div id="niceng157er13.tab4_3"><p class="no_margin">Downgraded by 1 or 2 increments because the point estimates varied widely across studies, unexplained by subgroup analysis. Random effects model utilised.</p></div></dd></dl><dl class="bkr_refwrap"><dt>4</dt><dd><div id="niceng157er13.tab4_4"><p class="no_margin">Absolute values calculated using the risk difference.</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13tab5"><div id="niceng157er13.tab5" class="table"><h3><span class="label">Table 5</span><span class="title">Clinical evidence summary: Posterior approach versus anterolateral approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab5/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab5_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab5_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab5_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab5_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab5_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_niceng157er13.tab5_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_niceng157er13.tab5_1_1_1_5" id="hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Anterolateral approach</th><th headers="hd_h_niceng157er13.tab5_1_1_1_5" id="hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Posterior approach (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mortality</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2 hd_h_niceng157er13.tab5_1_1_1_3 hd_h_niceng157er13.tab5_1_1_1_4 hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1 hd_h_niceng157er13.tab5_1_1_2_2" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Not reported</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Quality of life</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2 hd_h_niceng157er13.tab5_1_1_1_3 hd_h_niceng157er13.tab5_1_1_1_4 hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1 hd_h_niceng157er13.tab5_1_1_2_2" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Not reported</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>Harris Hip Score. Scale from: 0 to 100.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>68</p>
|
|
<p>(1 study)</p>
|
|
<p>6 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>82.7</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>1.6 lower</p>
|
|
<p>(4.82 lower to 1.62 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 2 years</p>
|
|
<p>Harris Hip Score. Scale from: 0 to 100.</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>196</p>
|
|
<p>(1 study)</p>
|
|
<p>37.9 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>91</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>1.3 higher</p>
|
|
<p>(0.41 lower to 3.01 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Revision later than 2 years</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>243</p>
|
|
<p>(2 studies)</p>
|
|
<p>37.9 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 0.36</p>
|
|
<p>(0.05 to 2.58)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25 per 1000</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>20 fewer per 1000</p>
|
|
<p>(from 50 fewer to 20 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dislocation later than 2 years</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>371</p>
|
|
<p>(4 studies)</p>
|
|
<p>37.9 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 1</p>
|
|
<p>(0.28 to 3.53)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27 per 1000</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>0 fewer per 1000</p>
|
|
<p>(from 40 fewer to 40 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reoperation later than 6 weeks up to 1 year</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>68</p>
|
|
<p>(1 study)</p>
|
|
<p>6 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 0.14</p>
|
|
<p>(0 to 6.82)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29 per 1000</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>30 fewer per 1000</p>
|
|
<p>(from 110 fewer to 50 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Superficial surgical site infection later than 6 weeks up to 1 year</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>60</p>
|
|
<p>(1 study)</p>
|
|
<p>12 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>MODERATE<sup>2</sup></p>
|
|
<p>due to imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Peto OR 7.65</p>
|
|
<p>(0.47 to 125.22)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">0 per 1000</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>70 more per 1000</p>
|
|
<p>(from 40 fewer to 170 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - blood loss (ml)</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>110</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>MODERATE<sup>2</sup></p>
|
|
<p>due to imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean intraoperative complications - blood loss (ml) in the control groups was</p>
|
|
<p>605</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean intraoperative complications - blood loss (ml) in the intervention groups was</p>
|
|
<p>228.82 lower</p>
|
|
<p>(303.1 to 154.54 lower)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes)</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>374</p>
|
|
<p>(3 studies)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup><sup>,</sup><sup>3</sup></p>
|
|
<p>due to risk of bias, inconsistency, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean surgery time (minutes) in the control groups was</p>
|
|
<p>98.1</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean surgery time (minutes) in the intervention groups was</p>
|
|
<p>9.34 higher</p>
|
|
<p>(5.01 lower to 23.69 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Pain (change score) VAS scale</td><td headers="hd_h_niceng157er13.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>22</p>
|
|
<p>(1 study)</p>
|
|
<p>12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean pain (change score) in the control groups was</p>
|
|
<p>−43.08</p>
|
|
</td><td headers="hd_h_niceng157er13.tab5_1_1_1_5 hd_h_niceng157er13.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean pain (change score) in the intervention groups was</p>
|
|
<p>7.28 lower</p>
|
|
<p>(24.1 lower to 9.54 higher)</p>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.tab5_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.tab5_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl><dl class="bkr_refwrap"><dt>3</dt><dd><div id="niceng157er13.tab5_3"><p class="no_margin">Downgraded by 1 or 2 increments because the point estimates varied widely across studies, unexplained by subgroup analysis. Random effects model utilised.</p></div></dd></dl><dl class="bkr_refwrap"><dt>4</dt><dd><div id="niceng157er13.tab5_4"><p class="no_margin">Absolute values calculated using the risk difference.</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13tab6"><div id="niceng157er13.tab6" class="table"><h3><span class="label">Table 6</span><span class="title">Clinical evidence summary: SuperPATH approach versus posterior approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab6/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab6_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab6_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab6_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab6_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.tab6_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_niceng157er13.tab6_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_niceng157er13.tab6_1_1_1_5" id="hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Posterior approach</th><th headers="hd_h_niceng157er13.tab6_1_1_1_5" id="hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with SuperPATH approach (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mortality</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2 hd_h_niceng157er13.tab6_1_1_1_3 hd_h_niceng157er13.tab6_1_1_1_4 hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1 hd_h_niceng157er13.tab6_1_1_2_2" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Not reported</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Quality of life</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2 hd_h_niceng157er13.tab6_1_1_1_3 hd_h_niceng157er13.tab6_1_1_1_4 hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1 hd_h_niceng157er13.tab6_1_1_2_2" colspan="5" rowspan="1" style="text-align:left;vertical-align:top;">Not reported</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs at 6 weeks or earlier</p>
|
|
<p>Barthel Index score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>92</p>
|
|
<p>(1 study)</p>
|
|
<p>1 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>64.46</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>6.21 higher</p>
|
|
<p>(2.68 to 9.74 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs at 6 weeks or earlier</p>
|
|
<p>Harris Hip Score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>92</p>
|
|
<p>(1 study)</p>
|
|
<p>1 weeks</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>69</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>4.8 higher</p>
|
|
<p>(3.01 to 6.59 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>Barthel Index score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>92</p>
|
|
<p>(1 study)</p>
|
|
<p>1 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>LOW<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>93.6</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>0.73 higher</p>
|
|
<p>(2.49 lower to 3.95 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>PROMs later than 6 weeks up to 1 year</p>
|
|
<p>Harris Hip Score</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>92</p>
|
|
<p>(1 study)</p>
|
|
<p>1 years</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the control groups was</p>
|
|
<p>91.6</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean proms in the intervention groups was</p>
|
|
<p>0.7 higher</p>
|
|
<p>(0.14 lower to 1.54 higher)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dislocation later than 6 weeks up to 1 year</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>92</p>
|
|
<p>(1 study)</p>
|
|
<p>12 months</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>VERY LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>RR 0.5</p>
|
|
<p>(0.05 to 5.32)</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43 per 1000</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>22 fewer per 1000</p>
|
|
<p>(from 41 fewer to 188 more)</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Length of stay (days)</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92 (1 study)</td><td headers="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>MODERATE<sup>1</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>The mean length of stay (days) in the control groups was</p>
|
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<p>11.4</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>The mean length of stay (days) in the intervention groups was</p>
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<p>3.1 lower</p>
|
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<p>(4.35 to 1.85 lower)</p>
|
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</td></tr><tr><td headers="hd_h_niceng157er13.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes)</td><td headers="hd_h_niceng157er13.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92 (1 study)</td><td headers="hd_h_niceng157er13.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>LOW<sup>1</sup><sup>,</sup><sup>2</sup></p>
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<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_niceng157er13.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>The mean surgery time (minutes) in the control groups was</p>
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<p>106.5</p>
|
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</td><td headers="hd_h_niceng157er13.tab6_1_1_1_5 hd_h_niceng157er13.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>The mean surgery time (minutes) in the intervention groups was</p>
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<p>2.9 lower</p>
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<p>(8.76 lower to 2.96 higher)</p>
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</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.tab6_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.tab6_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13tab7"><div id="niceng157er13.tab7" class="table"><h3><span class="label">Table 7</span><span class="title">Health economic evidence profile: Anterior THR versus posterior THR versus lateral THR</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab7/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab7_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Study</th><th id="hd_h_niceng157er13.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Applicability</th><th id="hd_h_niceng157er13.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Limitations</th><th id="hd_h_niceng157er13.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Other comments</th><th id="hd_h_niceng157er13.tab7_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Incremental cost</th><th id="hd_h_niceng157er13.tab7_1_1_1_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Incremental effects</th><th id="hd_h_niceng157er13.tab7_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Cost effectiveness</th><th id="hd_h_niceng157er13.tab7_1_1_1_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Uncertainty</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Petis 2016<a class="bibr" href="#niceng157er13.ref82" rid="niceng157er13.ref82"><sup>82</sup></a></p>
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<p>Canada</p>
|
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</td><td headers="hd_h_niceng157er13.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Partially<sup>(a)</sup> applicable</td><td headers="hd_h_niceng157er13.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Potentially serious limitations<sup>(b)</sup></td><td headers="hd_h_niceng157er13.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A prospective cohort study micro-costing 3 interventions; anterior posterior; and lateral THR, each carried out by a single surgeon. A 3-month time horizon was taken.</td><td headers="hd_h_niceng157er13.tab7_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>
|
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<b>Total cost of procedure (mean per patient):</b>
|
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</p>
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<p>Anterior: £4,155</p>
|
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<p>Posterior: £4,716</p>
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<p>Lateral: £4,469</p>
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</td><td headers="hd_h_niceng157er13.tab7_1_1_1_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>
|
|
<b>Inpatient LOS (mean days per patient):</b>
|
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</p>
|
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<p>Intervention 1: 1.42</p>
|
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<p>Intervention 2: 2.74</p>
|
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<p>Intervention 3: 2.68</p>
|
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</td><td headers="hd_h_niceng157er13.tab7_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The anterior THR approach is cost saving compared to the posterior and lateral approaches</td><td headers="hd_h_niceng157er13.tab7_1_1_1_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No sensitivity analysis was conducted</td></tr><tr><td headers="hd_h_niceng157er13.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Sharma 2019<a class="bibr" href="#niceng157er13.ref102" rid="niceng157er13.ref102"><sup>102</sup></a></p>
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<p>Canada</p>
|
|
</td><td headers="hd_h_niceng157er13.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Partially applicable<sup>(c)</sup></td><td headers="hd_h_niceng157er13.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Potentially serious limitations<sup>(d)</sup></td><td headers="hd_h_niceng157er13.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A retrospective matched cohort study that used two costing models to compare initial inpatient stay costs of 3 interventions: anterior posterior; and lateral THR. Time horizon was initial inpatient stay.</td><td headers="hd_h_niceng157er13.tab7_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>
|
|
<b>Total cost of procedure (mean per patient):</b>
|
|
</p>
|
|
<p>Anterior: £5,234</p>
|
|
<p>Posterior: £6,156</p>
|
|
<p>Lateral: £6,361</p>
|
|
</td><td headers="hd_h_niceng157er13.tab7_1_1_1_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>
|
|
<b>Inpatient LOS (mean days per patient):</b>
|
|
</p>
|
|
<p>Intervention 1: 0.25</p>
|
|
<p>Intervention 2: 3.54</p>
|
|
<p>Intervention 3: 3.12</p>
|
|
</td><td headers="hd_h_niceng157er13.tab7_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The anterior THR approach is cost saving compared to the posterior and lateral approaches</td><td headers="hd_h_niceng157er13.tab7_1_1_1_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No sensitivity analysis was conducted</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">Abbreviations: LOS: length of stay; THR: total hip replacement</p></div></dd></dl><dl class="bkr_refwrap"><dt>(a)</dt><dd><div id="niceng157er13.tab7_1"><p class="no_margin">A cost comparison study with a Canadian perspective. No quality of life included.</p></div></dd></dl><dl class="bkr_refwrap"><dt>(b)</dt><dd><div id="niceng157er13.tab7_2"><p class="no_margin">Quality of life is not included as an outcome; the follow-up may be too short to understand the long term complications of the interventions; no sensitivity analysis was conducted; no multivariate analysis conducted to adjust for confounders, although a 1-way ANOVA showed no significant difference in age, sex, BMI, side operated on, primary diagnosis and age adjust Charlson Comorbidity Index.</p></div></dd></dl><dl class="bkr_refwrap"><dt>(c)</dt><dd><div id="niceng157er13.tab7_3"><p class="no_margin">A cost comparison study with a Canadian perspective. No quality of life included.</p></div></dd></dl><dl class="bkr_refwrap"><dt>(d)</dt><dd><div id="niceng157er13.tab7_4"><p class="no_margin">Quality of life is not included as an outcome; the follow-up may be too short to understand the long term complications of the interventions; no sensitivity analysis was conducted; no multivariate analysis conducted to adjust for confounders although patients were retrospectively matched</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13tab8"><div id="niceng157er13.tab8" class="table"><h3><span class="label">Table 8</span><span class="title">Weighted average unit costs for HRG HN12 (Elective Very Major Hip Procedures for Non-Trauma) including excess bed days</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.tab8/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.tab8_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Intervention/Diagnosis</th><th id="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Reference cost HRG</th><th id="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">National average unit cost</th><th id="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Average cost of excess bed day</th><th id="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Weighted national average</th><th id="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Weighted average length of stay</th><th id="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">NOTES</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma</td><td headers="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma with CC Score 10+ (HN12A); as recorded for Elective Inpatients</td><td headers="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£11,262</td><td headers="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£446</td><td headers="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£11,508</td><td headers="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">12.28</td><td headers="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The number of data submissions for this code was 112, with 379 units of activity.</td></tr><tr><td headers="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma</td><td headers="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma with CC Score 8-9 (HN12B); as recorded for Elective Inpatients</td><td headers="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£8,725</td><td headers="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£360</td><td headers="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£8,815</td><td headers="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">7.98</td><td headers="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The number of data submissions for this code was 127, with 770 units of activity.</td></tr><tr><td headers="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma</td><td headers="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma with CC Score 6-7 (HN12C); as recorded for Elective Inpatients</td><td headers="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£7,616</td><td headers="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£357</td><td headers="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£7,767</td><td headers="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">6.24</td><td headers="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The number of data submissions for this code was 135, with 2259 units of activity.</td></tr><tr><td headers="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma</td><td headers="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma with CC Score 4-5 (HN12D); as recorded for Elective Inpatients</td><td headers="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£7,008</td><td headers="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£412</td><td headers="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£7,140</td><td headers="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">4.98</td><td headers="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The number of data submissions for this code was 137, with 5923 units of activity.</td></tr><tr><td headers="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma</td><td headers="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma with CC Score 2-3 (HN12E); as recorded for Elective Inpatients</td><td headers="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£6,514</td><td headers="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£411</td><td headers="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£6,634</td><td headers="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">3.87</td><td headers="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The number of data submissions for this code was 138, with 14705 units of activity.</td></tr><tr><td headers="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma</td><td headers="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma with CC Score 0-1 (HN12F); as recorded for Elective Inpatients</td><td headers="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£6,061</td><td headers="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£413</td><td headers="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£6,119</td><td headers="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">3.21</td><td headers="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The number of data submissions for this code was 139, with 23488 units of activity.</td></tr><tr><td headers="hd_h_niceng157er13.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Very Major Hip Procedures for Non-Trauma</td><td headers="hd_h_niceng157er13.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Weighted for complications and co morbidities for HRG codes: HN12A, HN12B, HN12C, HN12D, HN12E and HN12F; as recorded for Elective Inpatients</td><td headers="hd_h_niceng157er13.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_niceng157er13.tab8_1_1_1_5" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">£6,571</td><td headers="hd_h_niceng157er13.tab8_1_1_1_6" rowspan="1" colspan="1" style="text-align:right;vertical-align:top;">3.93</td><td headers="hd_h_niceng157er13.tab8_1_1_1_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">Source: NHS Reference costs 2017/2018<a class="bibr" href="#niceng157er13.ref21" rid="niceng157er13.ref21"><sup>21</sup></a></p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13appatab1"><div id="niceng157er13.appa.tab1" class="table"><h3><span class="label">Table 10</span><span class="title">Health economic review protocol</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appa.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appa.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_niceng157er13.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Review question</th><th id="hd_h_niceng157er13.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">All questions – health economic evidence</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>Objectives</b>
|
|
</td><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">To identify health economic studies relevant to any of the review questions.</td></tr><tr><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>Search criteria</b>
|
|
</td><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul><li class="half_rhythm"><div>Populations, interventions and comparators must be as specified in the clinical review protocol above.</div></li><li class="half_rhythm"><div>Studies must be of a relevant health economic study design (cost–utility analysis, cost-effectiveness analysis, cost–benefit analysis, cost–consequences analysis, comparative cost analysis).</div></li><li class="half_rhythm"><div>Studies must not be a letter, editorial or commentary, or a review of health economic evaluations. (Recent reviews will be ordered although not reviewed. The bibliographies will be checked for relevant studies, which will then be ordered.)</div></li><li class="half_rhythm"><div>Unpublished reports will not be considered unless submitted as part of a call for evidence.</div></li><li class="half_rhythm"><div>Studies must be in English.</div></li></ul></td></tr><tr><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>Search strategy</b>
|
|
</td><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A health economic study search will be undertaken using population-specific terms and a health economic study filter – see <a href="#niceng157er13.appb">appendix B</a> below.</td></tr><tr><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>Review strategy</b>
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</td><td headers="hd_h_niceng157er13.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Studies not meeting any of the search criteria above will be excluded. Studies published before 2003, abstract-only studies and studies from low or middle-income countries (e.g. most non-OECD countries) or the USA will also be excluded.</p>
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<p>Each remaining study will be assessed for applicability and methodological limitations using the NICE economic evaluation checklist which can be found in appendix H of Developing NICE guidelines: the manual (2014).<a class="bibr" href="#niceng157er13.ref72" rid="niceng157er13.ref72"><sup>72</sup></a></p>
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<p><b>Inclusion and exclusion criteria</b>
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<ul><li class="half_rhythm"><div>If a study is rated as both ‘Directly applicable’ and with ‘Minor limitations’ then it will be included in the guideline. A health economic evidence table will be completed and it will be included in the health economic evidence profile.</div></li><li class="half_rhythm"><div>If a study is rated as either ‘Not applicable’ or with ‘Very serious limitations’ then it will usually be excluded from the guideline. If it is excluded then a health economic evidence table will not be completed and it will not be included in the health economic evidence profile.</div></li><li class="half_rhythm"><div>If a study is rated as ‘Partially applicable’, with ‘Potentially serious limitations’ or both then there is discretion over whether it should be included.</div></li></ul>
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<b>Where there is discretion</b></p>
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<p>The health economist will make a decision based on the relative applicability and quality of the available evidence for that question, in discussion with the guideline committee if required. The ultimate aim is to include health economic studies that are helpful for decision-making in the context of the guideline and the current NHS setting. If several studies are considered of sufficiently high applicability and methodological quality that they could all be included, then the health economist, in discussion with the committee if required, may decide to include only the most applicable studies and to selectively exclude the remaining studies. All studies excluded on the basis of applicability or methodological limitations will be listed with explanation in the excluded health economic studies appendix below.</p>
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<p>The health economist will be guided by the following hierarchies.</p>
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<p><i>Setting:</i>
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<ul><li class="half_rhythm"><div>UK NHS (most applicable).</div></li><li class="half_rhythm"><div>OECD countries with predominantly public health insurance systems (for example, France, Germany, Sweden).</div></li><li class="half_rhythm"><div>OECD countries with predominantly private health insurance systems (for example, Switzerland).</div></li><li class="half_rhythm"><div>Studies set in non-OECD countries or in the USA will be excluded before being assessed for applicability and methodological limitations.</div></li></ul>
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<i>Health economic study type:</i>
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<ul><li class="half_rhythm"><div>Cost–utility analysis (most applicable).</div></li><li class="half_rhythm"><div>Other type of full economic evaluation (cost–benefit analysis, cost-effectiveness analysis, cost–consequences analysis).</div></li><li class="half_rhythm"><div>Comparative cost analysis.</div></li><li class="half_rhythm"><div>Non-comparative cost analyses including cost-of-illness studies will be excluded before being assessed for applicability and methodological limitations.</div></li></ul>
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<i>Year of analysis:</i>
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<ul><li class="half_rhythm"><div>The more recent the study, the more applicable it will be.</div></li><li class="half_rhythm"><div>Studies published in 2003 or later but that depend on unit costs and resource data entirely or predominantly from before 2003 will be rated as ‘Not applicable’.</div></li><li class="half_rhythm"><div>Studies published before 2003 will be excluded before being assessed for applicability and methodological limitations.</div></li></ul>
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<i>Quality and relevance of effectiveness data used in the health economic analysis:</i>
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<ul><li class="half_rhythm"><div>The more closely the clinical effectiveness data used in the health economic analysis match with the outcomes of the studies included in the clinical review the more useful the analysis will be for decision-making in the guideline.</div></li></ul></p>
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</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab1"><div id="niceng157er13.appb.tab1" class="table"><h3><span class="label">Table 11</span><span class="title">Database date parameters and filters used</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_niceng157er13.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Database</th><th id="hd_h_niceng157er13.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dates searched</th><th id="hd_h_niceng157er13.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search filter used</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Medline (OVID)</td><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1946 – 01 May 2019</td><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Exclusions</p>
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<p>Randomised controlled trials</p>
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<p>Systematic review studies</p>
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<p>Observational studies</p>
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</td></tr><tr><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Embase (OVID)</td><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1974 – 01 May 2019</td><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Exclusions</p>
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<p>Randomised controlled trials</p>
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<p>Systematic review studies</p>
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<p>Observational studies</p>
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</td></tr><tr><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The Cochrane Library (Wiley)</td><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Cochrane Reviews to 2019 Issue 5 of 12</p>
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<p>CENTRAL to 2019 Issue 5 of 12</p>
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</td><td headers="hd_h_niceng157er13.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab2"><div id="niceng157er13.appb.tab2" class="table"><h3><span class="title">Medline (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab2_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Arthroplasty, Replacement, Hip/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hip Prosthesis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((joint* or hip*) adj3 (surger* or replace* or prosthe* or endoprosthe* or implant* or artificial or arthroplast* or hemiarthroplast*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1 or 3</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">news/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp historical article/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anecdotes as Topic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">comment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/5-12</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13 not 14</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animals/ not humans/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animals, Laboratory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experimentation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Models, Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodentia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/15-21</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4 not 22</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 23 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((surgery or surgical or hip) adj4 approach*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(direct adj2 (anterior or superior)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(smithpeters?n or smith-peters?n).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(anterolateral* or watson-jones).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(posterior or moore or southern).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(supercapsular or percutaneously or superpath or path).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/25-30</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24 and 31</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">controlled clinical trial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomi#ed.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">placebo.ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomly.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Clinical Trials as topic.sh.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">trial.ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/33-39</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meta-Analysis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Meta-Analysis as Topic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(meta analy* or metanaly* or metaanaly* or meta regression).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((systematic* or evidence*) adj3 (review* or overview*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(reference list* or bibliograph* or hand search* or manual search* or relevant journals).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(search strategy or search criteria or systematic search or study selection or data extraction).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(search* adj4 literature).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(medline or pubmed or cochrane or embase or psychlit or psyclit or psychinfo or psycinfo or cinahl or science citation index or bids or cancerlit).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cochrane.jw.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((multiple treatment* or indirect or mixed) adj2 comparison*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/41-50</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Epidemiologic studies/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Observational study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Cohort studies/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cohort adj (study or studies or analys* or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((follow up or observational or uncontrolled or non randomi#ed or epidemiologic*) adj (study or studies or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((longitudinal or retrospective or prospective or cross sectional) and (study or studies or review or analys* or cohort* or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Controlled Before-After Studies/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Historically Controlled Study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Interrupted Time Series Analysis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(before adj2 after adj2 (study or studies or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/53-62</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp case control study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case control*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/64-65</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63 or 66</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Cross-sectional studies/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cross sectional and (study or studies or review or analys* or cohort* or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/68-69</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63 or 70</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63 or 66 or 70</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32 and (40 or 51 or 71)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab3"><div id="niceng157er13.appb.tab3" class="table"><h3><span class="title">Embase (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab3_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hip replacement/ or hip arthroplasty/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hip Prosthesis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((joint* or hip*) adj3 (surger* or replace* or prosthe* or endoprosthe* or implant* or artificial or arthroplast* or hemiarthroplast*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-3</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter.pt. or letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">note.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/ or case study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/5-9</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10 not 11</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal/ not human/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">nonhuman/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experiment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Experimental Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodent/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/12-19</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4 not 20</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 21 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((surgery or surgical or hip) adj4 approach*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(direct adj2 (anterior or superior)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(smithpeters?n or smith-peters?n).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(anterolateral* or watson-jones).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(posterior or moore or southern).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(supercapsular or percutaneously or superpath or path).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/23-28</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22 and 29</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">factorial*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(crossover* or cross over*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((doubl* or singl*) adj blind*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(assign* or allocat* or volunteer* or placebo*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">crossover procedure/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">single blind procedure/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">double blind procedure/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/31-39</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">systematic review/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">meta-analysis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(meta analy* or metanaly* or metaanaly* or meta regression).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((systematic* or evidence*) adj3 (review* or overview*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(reference list* or bibliograph* or hand search* or manual search* or relevant journals).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(search strategy or search criteria or systematic search or study selection or data extraction).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(search* adj4 literature).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(medline or pubmed or cochrane or embase or psychlit or psyclit or psychinfo or psycinfo or cinahl or science citation index or bids or cancerlit).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cochrane.jw.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((multiple treatment* or indirect or mixed) adj2 comparison*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/41-50</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Clinical study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Observational study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">family study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">longitudinal study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">retrospective study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">prospective study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cohort analysis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">follow-up/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cohort*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60 and 61</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cohort adj (study or studies or analys* or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((follow up or observational or uncontrolled or non randomi#ed or epidemiologic*) adj (study or studies or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((longitudinal or retrospective or prospective or cross sectional) and (study or studies or review or analys* or cohort* or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(before adj2 after adj2 (study or studies or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/53-59,62-66</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp case control study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case control*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/68-69</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67 or 70</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cross-sectional study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cross sectional and (study or studies or review or analys* or cohort* or data)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/72-73</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67 or 74</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67 or 70 or 74</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30 and (40 or 51 or 75)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab4"><div id="niceng157er13.appb.tab4" class="table"><h3><span class="title">Cochrane Library (Wiley) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab4_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Arthroplasty, Replacement, Hip] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Hip Prosthesis] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((joint* or hip*) near/3 (surger* or replace* or prosthe* or endoprosthe* or implant* or artificial or arthroplast* or hemiarthroplast*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(OR #1-#3)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((surgery or surgical or hip) near/4 approach*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(direct near/2 (anterior or superior)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(smithpetersen or smithpeterson or smith-petersen or smith-peterson):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(anterolateral* or watson-jones):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(posterior or moore or southern):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(supercapsular or percutaneously or superpath or path):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(OR #5-#10)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#4 AND #11</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab5"><div id="niceng157er13.appb.tab5" class="table"><h3><span class="label">Table 12</span><span class="title">Database date parameters and filters used</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab5/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab5_lrgtbl__"><table><thead><tr><th id="hd_h_niceng157er13.appb.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Database</th><th id="hd_h_niceng157er13.appb.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dates searched</th><th id="hd_h_niceng157er13.appb.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search filter used</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Medline</td><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2014 – 01 May 2019</td><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Exclusions</p>
|
|
<p>Health economics studies</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Embase</td><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2014 – 01 May 2019</td><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Exclusions</p>
|
|
<p>Health economics studies</p>
|
|
</td></tr><tr><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Centre for Research and Dissemination (CRD)</td><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>HTA - Inception – 01 May 2019</p>
|
|
<p>NHSEED - Inception to March 2015</p>
|
|
</td><td headers="hd_h_niceng157er13.appb.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab6"><div id="niceng157er13.appb.tab6" class="table"><h3><span class="title">Medline (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab6/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab6_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">arthroplasty/ or arthroplasty, replacement/ or arthroplasty, replacement, hip/ or arthroplasty, replacement, knee/ or arthroplasty, replacement, shoulder/ or hemiarthroplasty/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">joint prosthesis/ or hip prosthesis/ or knee prosthesis/ or shoulder prosthesis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((joint* or knee* or shoulder* or hip*) adj5 (surger* or replace* or prosthe* or endoprosthe* or implant* or artificial or arthroplast* or hemiarthroplast*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-3</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">news/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp historical article/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anecdotes as Topic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">comment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/5-12</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13 not 14</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animals/ not humans/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animals, Laboratory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experimentation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Models, Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodentia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/15-21</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4 not 22</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 23 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Economics/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Value of life/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp “Costs and Cost Analysis”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Economics, Hospital/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Economics, Medical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Economics, Nursing/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Economics, Pharmaceutical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp “Fees and Charges”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Budgets/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cost*.ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(economic* or pharmaco?economic*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(price* or pricing*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cost* adj2 (effective* or utilit* or benefit* or minimi* or unit* or estimat* or variable*)).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(financ* or fee or fees).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(value adj2 (money or monetary)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/25-40</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24 and 41</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab7"><div id="niceng157er13.appb.tab7" class="table"><h3><span class="title">Embase (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab7/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab7_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*arthroplasty/ or *replacement arthroplasty/ or *hip replacement/ or *knee replacement/ or *shoulder replacement/ or *hemiarthroplasty/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*joint prosthesis/ or *hip prosthesis/ or *knee prosthesis/ or *shoulder prosthesis/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((joint* or knee* or shoulder* or hip*) adj5 (surger* or replace* or prosthe* or endoprosthe* or implant* or artificial or arthroplast* or hemiarthroplast*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-3</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter.pt. or letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">note.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/ or case study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/5-9</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10 not 11</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal/ not human/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">nonhuman/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experiment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Experimental Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodent/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/12-19</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4 not 20</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 21 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">health economics/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp economic evaluation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp health care cost/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp fee/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">funding/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cost*.ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(economic* or pharmaco?economic*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(price* or pricing*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cost* adj2 (effective* or utilit* or benefit* or minimi* or unit* or estimat* or variable*)).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(financ* or fee or fees).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(value adj2 (money or monetary)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/23-35</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22 and 36</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appbtab8"><div id="niceng157er13.appb.tab8" class="table"><h3><span class="title">NHS EED and HTA (CRD) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appb.tab8/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appb.tab8_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR arthroplasty</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR arthroplasty, replacement</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR arthroplasty, replacement, hip</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR arthroplasty, replacement, knee</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR arthroplasty, replacement, shoulder</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR hemiarthroplasty</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR joint prosthesis</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR hip prosthesis</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR knee prosthesis</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR shoulder prosthesis</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((joint* or knee* or shoulder* or hip*) adj5 (surger* or replace* or prosthe* or endoprosthe* or implant* or artificial or arthroplast* or hemiarthroplast*)))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11) IN NHSEED</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11) IN HTA</td></tr></tbody></table></div></div></article><article data-type="fig" id="figobniceng157er13appcfig1"><div id="niceng157er13.appc.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%201.%20Flow%20chart%20of%20clinical%20study%20selection%20for%20the%20review%20of%20hip%20replacement.&p=BOOKS&id=561418_niceng157er13appcf1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appcf1.jpg" alt="Figure 1. Flow chart of clinical study selection for the review of hip replacement." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 1</span><span class="title">Flow chart of clinical study selection for the review of hip replacement</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig1"><div id="niceng157er13.appe.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%202.%20Quality%20of%20life%2C%20SF-12%20and%20SF-36%20scale%2C%20mental%20subscales%2C%20high%20is%20good%20outcome%2C%206%20weeks%20or%20earlier.&p=BOOKS&id=561418_niceng157er13appef1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef1.jpg" alt="Figure 2. Quality of life, SF-12 and SF-36 scale, mental subscales, high is good outcome, 6 weeks or earlier." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 2</span><span class="title">Quality of life, SF-12 and SF-36 scale, mental subscales, high is good outcome, 6 weeks or earlier</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig2"><div id="niceng157er13.appe.fig2" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%203.%20Quality%20of%20life%2C%20SF-12%20and%20SF-36%20scale%2C%20physical%20subscales%2C%20high%20is%20good%20outcome%2C%206%20weeks%20or%20earlier.&p=BOOKS&id=561418_niceng157er13appef2.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef2.jpg" alt="Figure 3. Quality of life, SF-12 and SF-36 scale, physical subscales, high is good outcome, 6 weeks or earlier." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 3</span><span class="title">Quality of life, SF-12 and SF-36 scale, physical subscales, high is good outcome, 6 weeks or earlier</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig3"><div id="niceng157er13.appe.fig3" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%204.%20Quality%20of%20life%2C%20SF-12%20and%20SF-36%20scale%2C%20mental%20subscales%2C%20high%20is%20good%20outcome%2C%20later%20than%206%20weeks%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef3.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef3.jpg" alt="Figure 4. Quality of life, SF-12 and SF-36 scale, mental subscales, high is good outcome, later than 6 weeks up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 4</span><span class="title">Quality of life, SF-12 and SF-36 scale, mental subscales, high is good outcome, later than 6 weeks up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig4"><div id="niceng157er13.appe.fig4" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%205.%20Quality%20of%20life%2C%20SF-12%20and%20SF-36%20scale%2C%20physical%20subscales%2C%20high%20is%20good%20outcome%2C%20later%20than%206%20weeks%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef4.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef4.jpg" alt="Figure 5. Quality of life, SF-12 and SF-36 scale, physical subscales, high is good outcome, later than 6 weeks up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 5</span><span class="title">Quality of life, SF-12 and SF-36 scale, physical subscales, high is good outcome, later than 6 weeks up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig5"><div id="niceng157er13.appe.fig5" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%206.%20PROMs%2C%20WOMAC%2C%20total%20score%2C%20high%20is%20good%2C%206%20weeks%20or%20earlier.&p=BOOKS&id=561418_niceng157er13appef5.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef5.jpg" alt="Figure 6. PROMs, WOMAC, total score, high is good, 6 weeks or earlier." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 6</span><span class="title">PROMs, WOMAC, total score, high is good, 6 weeks or earlier</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig6"><div id="niceng157er13.appe.fig6" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%207.%20PROMs%2C%20Harris%20Hip%20Score%2C%200-100%2C%20high%20is%20good%2C%206%20weeks%20or%20earlier.&p=BOOKS&id=561418_niceng157er13appef6.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef6.jpg" alt="Figure 7. PROMs, Harris Hip Score, 0-100, high is good, 6 weeks or earlier." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 7</span><span class="title">PROMs, Harris Hip Score, 0-100, high is good, 6 weeks or earlier</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig7"><div id="niceng157er13.appe.fig7" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%208.%20PROMs%2C%20WOMAC%2C%20total%20score%2C%20high%20is%20good%2C%20later%20than%206%20weeks%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef7.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef7.jpg" alt="Figure 8. PROMs, WOMAC, total score, high is good, later than 6 weeks up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 8</span><span class="title">PROMs, WOMAC, total score, high is good, later than 6 weeks up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig8"><div id="niceng157er13.appe.fig8" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%209.%20PROMs%2C%20Harris%20Hip%20Score%2C%200-100%2C%20high%20is%20good%2C%20later%20than%206%20weeks%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef8.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef8.jpg" alt="Figure 9. PROMs, Harris Hip Score, 0-100, high is good, later than 6 weeks up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 9</span><span class="title">PROMs, Harris Hip Score, 0-100, high is good, later than 6 weeks up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig9"><div id="niceng157er13.appe.fig9" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2010.%20Revision%2C%205%20years.&p=BOOKS&id=561418_niceng157er13appef9.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef9.jpg" alt="Figure 10. Revision, 5 years." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 10</span><span class="title">Revision, 5 years</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig10"><div id="niceng157er13.appe.fig10" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2011.%20Dislocation%2C%205%20years.&p=BOOKS&id=561418_niceng157er13appef10.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef10.jpg" alt="Figure 11. Dislocation, 5 years." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 11</span><span class="title">Dislocation, 5 years</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig11"><div id="niceng157er13.appe.fig11" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2012.%20Deep%20Infection.&p=BOOKS&id=561418_niceng157er13appef11.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef11.jpg" alt="Figure 12. Deep Infection." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 12</span><span class="title">Deep Infection</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig12"><div id="niceng157er13.appe.fig12" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2013.%20Deep%20Infection.&p=BOOKS&id=561418_niceng157er13appef12.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef12.jpg" alt="Figure 13. Deep Infection." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 13</span><span class="title">Deep Infection</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig13"><div id="niceng157er13.appe.fig13" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2014.%20Intraoperative%20complications%20-%20lateral%20femoral%20cutaneous%20nerve%20injury%2C%208%20days.&p=BOOKS&id=561418_niceng157er13appef13.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef13.jpg" alt="Figure 14. Intraoperative complications - lateral femoral cutaneous nerve injury, 8 days." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 14</span><span class="title">Intraoperative complications - lateral femoral cutaneous nerve injury, 8 days</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig14"><div id="niceng157er13.appe.fig14" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2015.%20Intraoperative%20complications%20-%20hyperesthesia.&p=BOOKS&id=561418_niceng157er13appef14.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef14.jpg" alt="Figure 15. Intraoperative complications - hyperesthesia." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 15</span><span class="title">Intraoperative complications - hyperesthesia</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig15"><div id="niceng157er13.appe.fig15" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2016.%20Intraoperative%20complications%20-%20blood%20loss%20(ml).&p=BOOKS&id=561418_niceng157er13appef15.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef15.jpg" alt="Figure 16. Intraoperative complications - blood loss (ml)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 16</span><span class="title">Intraoperative complications - blood loss (ml)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig16"><div id="niceng157er13.appe.fig16" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2017.%20Surgery%20time%20(minutes).&p=BOOKS&id=561418_niceng157er13appef16.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef16.jpg" alt="Figure 17. Surgery time (minutes)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 17</span><span class="title">Surgery time (minutes)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig17"><div id="niceng157er13.appe.fig17" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2018.%20Length%20of%20stay%20(days).&p=BOOKS&id=561418_niceng157er13appef17.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef17.jpg" alt="Figure 18. Length of stay (days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 18</span><span class="title">Length of stay (days)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig18"><div id="niceng157er13.appe.fig18" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2019.%20Quality%20of%20life%2C%20EQ-5D%2C%20HOOS%20(QOL%20subscale)%20high%20is%20good%20outcome%2C%206%20weeks%20or%20earlier.&p=BOOKS&id=561418_niceng157er13appef18.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef18.jpg" alt="Figure 19. Quality of life, EQ-5D, HOOS (QOL subscale) high is good outcome, 6 weeks or earlier." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 19</span><span class="title">Quality of life, EQ-5D, HOOS (QOL subscale) high is good outcome, 6 weeks or earlier</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig19"><div id="niceng157er13.appe.fig19" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2020.%20Quality%20of%20life%2C%20EQ-5D%2C%20HOOS%20(QOL%20subscale)%20high%20is%20good%20outcome%2C%20later%20than%206%20weeks%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef19.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef19.jpg" alt="Figure 20. Quality of life, EQ-5D, HOOS (QOL subscale) high is good outcome, later than 6 weeks up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 20</span><span class="title">Quality of life, EQ-5D, HOOS (QOL subscale) high is good outcome, later than 6 weeks up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig20"><div id="niceng157er13.appe.fig20" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2021.%20Quality%20of%20life%2C%20SF-12%20scale%2C%20mental%20subscales%2C%20high%20is%20good%20outcome%2C%20later%20than%206%20weeks%20or%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef20.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef20.jpg" alt="Figure 21. Quality of life, SF-12 scale, mental subscales, high is good outcome, later than 6 weeks or up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 21</span><span class="title">Quality of life, SF-12 scale, mental subscales, high is good outcome, later than 6 weeks or up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig21"><div id="niceng157er13.appe.fig21" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2022.%20Quality%20of%20life%2C%20SF-12%20scale%2C%20physical%20subscales%2C%20high%20is%20good%20outcome%2C%20later%20than%206%20weeks%20or%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef21.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef21.jpg" alt="Figure 22. Quality of life, SF-12 scale, physical subscales, high is good outcome, later than 6 weeks or up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 22</span><span class="title">Quality of life, SF-12 scale, physical subscales, high is good outcome, later than 6 weeks or up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig22"><div id="niceng157er13.appe.fig22" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2023.%20PROMs%2C%20WOMAC%2C%200-96%2C%20high%20is%20poor.&p=BOOKS&id=561418_niceng157er13appef22.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef22.jpg" alt="Figure 23. PROMs, WOMAC, 0-96, high is poor." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 23</span><span class="title">PROMs, WOMAC, 0-96, high is poor</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig23"><div id="niceng157er13.appe.fig23" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2024.%20PROMs%2C%20Oxford%20Hip%20Score%2C%200-48%2C%20high%20is%20good.&p=BOOKS&id=561418_niceng157er13appef23.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef23.jpg" alt="Figure 24. PROMs, Oxford Hip Score, 0-48, high is good." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 24</span><span class="title">PROMs, Oxford Hip Score, 0-48, high is good</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig24"><div id="niceng157er13.appe.fig24" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2025.%20PROMs%2C%20Harris%20Hip%20Score%2C%200-100%2C%20high%20is%20good.&p=BOOKS&id=561418_niceng157er13appef24.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef24.jpg" alt="Figure 25. PROMs, Harris Hip Score, 0-100, high is good." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 25</span><span class="title">PROMs, Harris Hip Score, 0-100, high is good</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig25"><div id="niceng157er13.appe.fig25" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2026.%20PROMs%2C%20HOOS%20score%20-%20symptoms%20subscale%2C%20high%20is%20good%2C%206%20weeks%20or%20earlier.&p=BOOKS&id=561418_niceng157er13appef25.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef25.jpg" alt="Figure 26. PROMs, HOOS score - symptoms subscale, high is good, 6 weeks or earlier." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 26</span><span class="title">PROMs, HOOS score - symptoms subscale, high is good, 6 weeks or earlier</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig26"><div id="niceng157er13.appe.fig26" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2027.%20PROMs%2C%20HOOS%20score%20-%20symptoms%20subscale%2C%20high%20is%20good%2C%20later%20than%206%20weeks%20or%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef26.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef26.jpg" alt="Figure 27. PROMs, HOOS score - symptoms subscale, high is good, later than 6 weeks or up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 27</span><span class="title">PROMs, HOOS score - symptoms subscale, high is good, later than 6 weeks or up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig27"><div id="niceng157er13.appe.fig27" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2028.%20PROMs%2C%20HOOS%20score%20-%20pain%20subscale%2C%20high%20is%20good%2C%20later%20than%206%20weeks%20or%20up%20to%201%20year.&p=BOOKS&id=561418_niceng157er13appef27.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef27.jpg" alt="Figure 28. PROMs, HOOS score - pain subscale, high is good, later than 6 weeks or up to 1 year." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 28</span><span class="title">PROMs, HOOS score - pain subscale, high is good, later than 6 weeks or up to 1 year</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig28"><div id="niceng157er13.appe.fig28" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2029.%20PROMs%2C%20HOOS%20Jr%20score%2C%20high%20is%20good%2C%20after%20at%20least%202%20years.&p=BOOKS&id=561418_niceng157er13appef28.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef28.jpg" alt="Figure 29. PROMs, HOOS Jr score, high is good, after at least 2 years." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 29</span><span class="title">PROMs, HOOS Jr score, high is good, after at least 2 years</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig29"><div id="niceng157er13.appe.fig29" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2030.%20PROMs%2C%20UCLA%20score%2C%206%20months%2C%20high%20is%20poor.&p=BOOKS&id=561418_niceng157er13appef29.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef29.jpg" alt="Figure 30. PROMs, UCLA score, 6 months, high is poor." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 30</span><span class="title">PROMs, UCLA score, 6 months, high is poor</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig30"><div id="niceng157er13.appe.fig30" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2031.%20PROMs%2C%20UCLA%20score%2C%20after%20at%20least%202%20years%2C%20high%20is%20good.&p=BOOKS&id=561418_niceng157er13appef30.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef30.jpg" alt="Figure 31. PROMs, UCLA score, after at least 2 years, high is good." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 31</span><span class="title">PROMs, UCLA score, after at least 2 years, high is good</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig31"><div id="niceng157er13.appe.fig31" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2032.%20Revision%2C%2012%20months.&p=BOOKS&id=561418_niceng157er13appef31.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef31.jpg" alt="Figure 32. Revision, 12 months." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 32</span><span class="title">Revision, 12 months</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig32"><div id="niceng157er13.appe.fig32" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2033.%20Dislocation%2C%2012%20months.&p=BOOKS&id=561418_niceng157er13appef32.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef32.jpg" alt="Figure 33. Dislocation, 12 months." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 33</span><span class="title">Dislocation, 12 months</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig33"><div id="niceng157er13.appe.fig33" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2034.%20Deep%20Infection%2C%206%20weeks.&p=BOOKS&id=561418_niceng157er13appef33.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef33.jpg" alt="Figure 34. Deep Infection, 6 weeks." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 34</span><span class="title">Deep Infection, 6 weeks</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig34"><div id="niceng157er13.appe.fig34" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2035.%20Intraoperative%20complications%20-%20lateral%20cutaneous%20nerve%20of%20the%20thigh%20neuropraxia%2C%2012%20weeks.&p=BOOKS&id=561418_niceng157er13appef34.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef34.jpg" alt="Figure 35. Intraoperative complications - lateral cutaneous nerve of the thigh neuropraxia, 12 weeks." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 35</span><span class="title">Intraoperative complications - lateral cutaneous nerve of the thigh neuropraxia, 12 weeks</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig35"><div id="niceng157er13.appe.fig35" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2036.%20Intraoperative%20complications%20-%20blood%20loss%20(ml).&p=BOOKS&id=561418_niceng157er13appef35.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef35.jpg" alt="Figure 36. Intraoperative complications - blood loss (ml)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 36</span><span class="title">Intraoperative complications - blood loss (ml)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig36"><div id="niceng157er13.appe.fig36" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2037.%20Length%20of%20stay%20(days).&p=BOOKS&id=561418_niceng157er13appef36.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef36.jpg" alt="Figure 37. Length of stay (days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 37</span><span class="title">Length of stay (days)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig37"><div id="niceng157er13.appe.fig37" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2038.%20Surgery%20time%20(minutes).&p=BOOKS&id=561418_niceng157er13appef37.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef37.jpg" alt="Figure 38. Surgery time (minutes)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 38</span><span class="title">Surgery time (minutes)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig38"><div id="niceng157er13.appe.fig38" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2039.%20PROMs%2C%20Harris%20Hip%20Score%2C%200-100%2C%20high%20is%20good.&p=BOOKS&id=561418_niceng157er13appef38.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef38.jpg" alt="Figure 39. PROMs, Harris Hip Score, 0-100, high is good." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 39</span><span class="title">PROMs, Harris Hip Score, 0-100, high is good</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig39"><div id="niceng157er13.appe.fig39" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2040.%20Revision%2C%2037.9%20months.&p=BOOKS&id=561418_niceng157er13appef39.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef39.jpg" alt="Figure 40. Revision, 37.9 months." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 40</span><span class="title">Revision, 37.9 months</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig40"><div id="niceng157er13.appe.fig40" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2041.%20Dislocation%2C%2037.9%20months.&p=BOOKS&id=561418_niceng157er13appef40.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef40.jpg" alt="Figure 41. Dislocation, 37.9 months." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 41</span><span class="title">Dislocation, 37.9 months</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig41"><div id="niceng157er13.appe.fig41" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2042.%20Reoperation%2C%206%20months.&p=BOOKS&id=561418_niceng157er13appef41.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef41.jpg" alt="Figure 42. Reoperation, 6 months." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 42</span><span class="title">Reoperation, 6 months</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig42"><div id="niceng157er13.appe.fig42" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2043.%20Superficial%20surgical%20site%20infection%2C%2012%20weeks.&p=BOOKS&id=561418_niceng157er13appef42.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef42.jpg" alt="Figure 43. Superficial surgical site infection, 12 weeks." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 43</span><span class="title">Superficial surgical site infection, 12 weeks</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig43"><div id="niceng157er13.appe.fig43" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2044.%20Intraoperative%20complications%20-%20blood%20loss%20(ml).&p=BOOKS&id=561418_niceng157er13appef43.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef43.jpg" alt="Figure 44. Intraoperative complications - blood loss (ml)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 44</span><span class="title">Intraoperative complications - blood loss (ml)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig44"><div id="niceng157er13.appe.fig44" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2045.%20Surgery%20time%20(minutes).&p=BOOKS&id=561418_niceng157er13appef44.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef44.jpg" alt="Figure 45. Surgery time (minutes)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 45</span><span class="title">Surgery time (minutes)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig45"><div id="niceng157er13.appe.fig45" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2046.%20Pain%20later%20than%206%20weeks%20up%20to%201%20year%2C%20VAS%20scale%2C%20high%20is%20poor%20outcome%20(change%20score).&p=BOOKS&id=561418_niceng157er13appef45.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef45.jpg" alt="Figure 46. Pain later than 6 weeks up to 1 year, VAS scale, high is poor outcome (change score)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 46</span><span class="title">Pain later than 6 weeks up to 1 year, VAS scale, high is poor outcome (change score)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig46"><div id="niceng157er13.appe.fig46" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2047.%20PROMs%2C%20Barthel%20Index%20score%2C%20high%20is%20good.&p=BOOKS&id=561418_niceng157er13appef46.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef46.jpg" alt="Figure 47. PROMs, Barthel Index score, high is good." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 47</span><span class="title">PROMs, Barthel Index score, high is good</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig47"><div id="niceng157er13.appe.fig47" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2048.%20PROMs%2C%20Harris%20Hip%20Score%2C%20high%20is%20good.&p=BOOKS&id=561418_niceng157er13appef47.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef47.jpg" alt="Figure 48. PROMs, Harris Hip Score, high is good." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 48</span><span class="title">PROMs, Harris Hip Score, high is good</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig48"><div id="niceng157er13.appe.fig48" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2049.%20Dislocation%2C%2012%20months.&p=BOOKS&id=561418_niceng157er13appef48.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef48.jpg" alt="Figure 49. Dislocation, 12 months." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 49</span><span class="title">Dislocation, 12 months</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig49"><div id="niceng157er13.appe.fig49" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2050.%20Length%20of%20stay%20(days).&p=BOOKS&id=561418_niceng157er13appef49.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef49.jpg" alt="Figure 50. Length of stay (days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 50</span><span class="title">Length of stay (days)</span></h3></div></article><article data-type="fig" id="figobniceng157er13appefig50"><div id="niceng157er13.appe.fig50" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2051.%20Surgery%20time%20(minutes).&p=BOOKS&id=561418_niceng157er13appef50.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appef50.jpg" alt="Figure 51. Surgery time (minutes)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 51</span><span class="title">Surgery time (minutes)</span></h3></div></article><article data-type="table-wrap" id="figobniceng157er13appftab1"><div id="niceng157er13.appf.tab1" class="table"><h3><span class="label">Table 13</span><span class="title">Clinical evidence profile: Direct anterior approach versus Anterolateral approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appf.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appf.tab1_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.appf.tab1_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_niceng157er13.appf.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_niceng157er13.appf.tab1_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_niceng157er13.appf.tab1_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab1_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_niceng157er13.appf.tab1_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab1_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1" id="hd_h_niceng157er13.appf.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">No of studies</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1" id="hd_h_niceng157er13.appf.tab1_1_1_2_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Design</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1" id="hd_h_niceng157er13.appf.tab1_1_1_2_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Risk of bias</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1" id="hd_h_niceng157er13.appf.tab1_1_1_2_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Inconsistency</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1" id="hd_h_niceng157er13.appf.tab1_1_1_2_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Indirectness</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1" id="hd_h_niceng157er13.appf.tab1_1_1_2_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Imprecision</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1" id="hd_h_niceng157er13.appf.tab1_1_1_2_7" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Other considerations</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_2" id="hd_h_niceng157er13.appf.tab1_1_1_2_8" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Direct anterior</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_2" id="hd_h_niceng157er13.appf.tab1_1_1_2_9" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Anterolateral approach</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_3" id="hd_h_niceng157er13.appf.tab1_1_1_2_10" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_3" id="hd_h_niceng157er13.appf.tab1_1_1_2_11" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 2 to 6 weeks; measured with: SF-12, SF-36 - mental subscale; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">SMD 0.15 lower (0.42 lower to 0.11 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
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<p>LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 2 to 6 weeks; measured with: SF-12, SF-36 - physical subscale; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 2.67 higher (0.34 to 5.01 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 3 to 12 months; measured with: SF-12, SF-36 - mental subscale; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.01 lower (3.2 lower to 1.18 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
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<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 3 to 12 months; measured with: SF-12, SF-36 - physical subscale; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>3</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">113</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.96 higher (3.28 lower to 7.21 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 6 weeks; measured with: WOMAC - total score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">56</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">82</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 3.75 lower (7.77 lower to 0.27 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 6 weeks; measured with: Harris Hip Score; range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">97</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">111</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.49 higher (2.35 lower to 3.33 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
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<p>LOW</p>
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|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_13_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 3 months; measured with: WOMAC - total score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">36</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">42</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 3.01 lower (8.34 lower to 2.32 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_15_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 3 to 12 months; measured with: Harris Hip Score; range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">162</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">163</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.95 higher (0.07 to 3.84 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_17_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Revision (follow-up 5 years)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/45</p>
|
|
<p>(2.2%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>0/42</p>
|
|
<p>(0%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 6.91 (0.14 to 349.18)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">20 more per 1000 (from 40 fewer to 80 more)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_19_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Dislocation (follow-up 1 to 5 years)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious indirectness<sup>4</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>4/122</p>
|
|
<p>(3.3%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/113</p>
|
|
<p>(0.88%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 3.2 (0.54 to 18.95)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">20 more per 1000 (from 20 fewer to 70 more)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_21_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Deep Infection (follow-up 8 days)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/35</p>
|
|
<p>(2.9%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>2/35</p>
|
|
<p>(5.7%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.50 (0.05 to 5.27)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">29 fewer per 1000 (from 54 fewer to 244 more)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_23_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Deep Infection (follow-up 5 years)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/45</p>
|
|
<p>(2.2%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>0/42</p>
|
|
<p>(0%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 6.91 (0.14 to 349.18)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">20 more per 1000 (from 40 fewer to 80 more)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_25_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - lateral femoral cutaneous nerve injury (follow-up 8 days)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>2/35</p>
|
|
<p>(5.7%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>0/35</p>
|
|
<p>(0%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 7.61 (0.47 to 124.15)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">60 more per 1000 (from 30 fewer to 150 more)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_27_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - hyperesthesia (follow-up 5 years)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>0/45</p>
|
|
<p>(0%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/42</p>
|
|
<p>(2.4%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 0.13 (0 to 6.37)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">20 fewer per 1000 (from 90 fewer to 40 more)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_29_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - blood loss (ml) (follow-up 6 weeks; Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">20</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">40</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 93.69 higher (292.87 lower to 480.26 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_31_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>3</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">153</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">170</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 9.57 higher (2.60 lower to 21.74 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_h_niceng157er13.appf.tab1_1_1_1_5" id="hd_b_niceng157er13.appf.tab1_1_1_33_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Length of stay (days) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_1 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_2 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_3 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_4 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>3</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_5 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_6 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_1 hd_h_niceng157er13.appf.tab1_1_1_2_7 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_8 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">56</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_2 hd_h_niceng157er13.appf.tab1_1_1_2_9 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">82</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_10 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_3 hd_h_niceng157er13.appf.tab1_1_1_2_11 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">SMD 0.79 lower (1.66 lower to 0.07 higher)</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_4 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab1_1_1_1_5 hd_b_niceng157er13.appf.tab1_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.appf.tab1_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.appf.tab1_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl><dl class="bkr_refwrap"><dt>3</dt><dd><div id="niceng157er13.appf.tab1_3"><p class="no_margin">Downgraded by 1 or 2 increments because the point estimates varied widely across studies, unexplained by subgroup analysis</p></div></dd></dl><dl class="bkr_refwrap"><dt>4</dt><dd><div id="niceng157er13.appf.tab1_4"><p class="no_margin">Downgraded by 1 or 2 increments because the meta-analysed time points vary slightly from the protocol.</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13appftab2"><div id="niceng157er13.appf.tab2" class="table"><h3><span class="label">Table 14</span><span class="title">Clinical evidence profile: Direct anterior approach versus Posterior approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appf.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appf.tab2_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.appf.tab2_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_niceng157er13.appf.tab2_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_niceng157er13.appf.tab2_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_niceng157er13.appf.tab2_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab2_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_niceng157er13.appf.tab2_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab2_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1" id="hd_h_niceng157er13.appf.tab2_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">No of studies</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1" id="hd_h_niceng157er13.appf.tab2_1_1_2_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Design</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1" id="hd_h_niceng157er13.appf.tab2_1_1_2_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Risk of bias</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1" id="hd_h_niceng157er13.appf.tab2_1_1_2_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Inconsistency</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1" id="hd_h_niceng157er13.appf.tab2_1_1_2_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Indirectness</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1" id="hd_h_niceng157er13.appf.tab2_1_1_2_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Imprecision</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1" id="hd_h_niceng157er13.appf.tab2_1_1_2_7" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Other considerations</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_2" id="hd_h_niceng157er13.appf.tab2_1_1_2_8" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Direct anterior</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_2" id="hd_h_niceng157er13.appf.tab2_1_1_2_9" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Posterior approach</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_3" id="hd_h_niceng157er13.appf.tab2_1_1_2_10" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_3" id="hd_h_niceng157er13.appf.tab2_1_1_2_11" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 2 to 6 weeks; measured with: EQ-5D, HOOS (QOL subscale); Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">82</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">78</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">SMD 0.40 lower (0.71 to 0.08 lower)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 3 to 12 months; measured with: EQ-5D, HOOS (QOL subscale); Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">131</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">130</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">SMD 0.03 lower (0.28 lower to 0.21 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
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<p>LOW</p>
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|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 1 years; measured with: SF-12 scale mental subscale; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">49</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">52</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.00 higher (2.21 lower to 2.21 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Quality of life (follow-up 1 years; measured with: SF-12 scale physical subscale; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">49</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">52</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.00 higher (2.35 lower to 4.35 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 2 weeks; measured with: WOMAC scale; range of scores: 0-96; Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">38</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">35</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 4.2 higher (4.1 lower to 12.5 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 12 weeks; measured with: WOMAC scale; range of scores: 0-96; Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">38</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">35</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 3.7 higher (1.98 lower to 9.38 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_13_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 2 weeks; measured with: Oxford Hip Score; range of scores: 0-48; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">38</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">35</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.7 lower (6.01 lower to 2.61 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>⨁◯◯◯</p>
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|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_15_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 12 weeks; measured with: Oxford Hip Score; range of scores: 0-48; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">38</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">35</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1 lower (3.4 lower to 1.4 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_17_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 6 weeks; measured with: Harris Hip Total Score; range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">44</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">43</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 8.1 lower (11.87 to 4.33 lower)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_19_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 6 to 12 months; measured with: Harris Hip Score; range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">153</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">155</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.28 lower (2.80 lower to 0.25 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_21_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 5 years; measured with: Harris Hip Score; range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">40</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">39</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.20 higher (3.87 lower to 4.27 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_23_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs - Symptoms subscale (follow-up 6 weeks; measured with: HOOS score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">44</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">43</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.5 higher (4.53 lower to 5.53 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_25_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs - symptoms subscale (follow-up 12 months; measured with: HOOS score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">93</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">95</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 3.12 lower (6.27 lower to 0.03 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_27_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up mean 1 years; measured with: HOOS score - pain subscale; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">49</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">52</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 2.00 lower (5.93 lower to 1.93 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_29_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up mean 6.2 years; measured with: HOOS Jr Total Score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">39</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">39</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 2.80 lower (7.84 lower to 2.24 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_29_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_31_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 6 months; measured with: UCLA score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">60</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">60</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.08 lower (0.5 lower to 0.34 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_31_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_33_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 5 years; measured with: UCLA score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">39</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">36</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.07 lower (0.87 lower to 0.73 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_33_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_35_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Revision (follow-up 12 months)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>2/82</p>
|
|
<p>(2.4%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/78</p>
|
|
<p>(1.3%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 1.84 (0.19 to 17.91)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">10 more per 1000 (from 40 fewer to 60 more)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_35_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_37_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Dislocation (follow-up 12 months)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>3/131</p>
|
|
<p>(2.3%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>2/130</p>
|
|
<p>(1.5%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 1.48 (0.25 to 8.61)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">10 more per 1000 (from 30 fewer to 40 more)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_37_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_39_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Deep Infection (follow-up 6 weeks)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious risk of bias</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/23</p>
|
|
<p>(4.3%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>2/23</p>
|
|
<p>(8.7%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.5 (0.05 to 5.14)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">43 fewer per 1000 (from 83 fewer to 360 more)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_39_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_41_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Function, mean time to ambulation with no assistive device (days) (follow-up mean 12 months; Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">27</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">27</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 12.30 higher (2.06 to 22.54 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_41_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_43_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - lateral cutaneous nerve of the thigh neuropraxia (follow-up 12 weeks)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>0/38</p>
|
|
<p>(0%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>29/35</p>
|
|
<p>(82.9%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 0.03 (0.01 to 0.08)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">830 fewer per 1000 (from 960 fewer to 700 fewer)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁⨁◯</p>
|
|
<p>MODERATE</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_43_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_45_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - blood loss (ml) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">83</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">83</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">SMD 0.69 lower (1.01 to 0.38 lower)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_45_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_47_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Length of stay (days) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">199</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">206</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.22 higher (0.03 to 0.41 higher)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_47_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_h_niceng157er13.appf.tab2_1_1_1_5" id="hd_b_niceng157er13.appf.tab2_1_1_49_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_1 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_2 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_3 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_4 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>3</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_5 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_6 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_1 hd_h_niceng157er13.appf.tab2_1_1_2_7 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_8 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">176</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_2 hd_h_niceng157er13.appf.tab2_1_1_2_9 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">178</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_10 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_3 hd_h_niceng157er13.appf.tab2_1_1_2_11 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 14.98 lower (21.77 to 8.20 lower)</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_4 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab2_1_1_1_5 hd_b_niceng157er13.appf.tab2_1_1_49_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.appf.tab2_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.appf.tab2_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl><dl class="bkr_refwrap"><dt>3</dt><dd><div id="niceng157er13.appf.tab2_3"><p class="no_margin">Downgraded by 1 or 2 increments because the point estimates varied widely across studies, unexplained by subgroup analysis</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13appftab3"><div id="niceng157er13.appf.tab3" class="table"><h3><span class="label">Table 15</span><span class="title">Clinical evidence profile: Anterolateral approach versus Posterior approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appf.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appf.tab3_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.appf.tab3_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_niceng157er13.appf.tab3_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_niceng157er13.appf.tab3_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_niceng157er13.appf.tab3_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab3_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_niceng157er13.appf.tab3_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab3_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1" id="hd_h_niceng157er13.appf.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">No of studies</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1" id="hd_h_niceng157er13.appf.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Design</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1" id="hd_h_niceng157er13.appf.tab3_1_1_2_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Risk of bias</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1" id="hd_h_niceng157er13.appf.tab3_1_1_2_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Inconsistency</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1" id="hd_h_niceng157er13.appf.tab3_1_1_2_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Indirectness</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1" id="hd_h_niceng157er13.appf.tab3_1_1_2_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Imprecision</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1" id="hd_h_niceng157er13.appf.tab3_1_1_2_7" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Other considerations</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_2" id="hd_h_niceng157er13.appf.tab3_1_1_2_8" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Posterior approach</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_2" id="hd_h_niceng157er13.appf.tab3_1_1_2_9" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Anterolateral approach</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_3" id="hd_h_niceng157er13.appf.tab3_1_1_2_10" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_3" id="hd_h_niceng157er13.appf.tab3_1_1_2_11" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 6 months; measured with: Harris Hip Score; range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">34</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">34</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.6 lower (4.82 lower to 1.62 higher)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up mean 37.9 months; measured with: Harris Hip Score; range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">97</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">99</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.3 higher (0.41 lower to 3.01 higher)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
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<p>LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Revision (follow-up 37.9 months)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>1/121</p>
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<p>(0.83%)</p>
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</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>3/122</p>
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<p>(2.5%)</p>
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</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 0.36 (0.05 to 2.58)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">20 fewer per 1000 (from 50 fewer to 20 more)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Dislocation (follow-up 37.9 months)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>5/185</p>
|
|
<p>(2.7%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>5/186</p>
|
|
<p>(2.7%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 1 (0.28 to 3.53)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">0 fewer per 1000 (from 40 fewer to 40 more)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Reoperation (follow-up 6 months)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>0/34</p>
|
|
<p>(0%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/34</p>
|
|
<p>(2.9%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 0.14 (0 to 6.82)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">30 fewer per 1000 (from 110 fewer to 50 more)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Superficial surgical site infection (follow-up 12 weeks)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious risk of bias</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>2/30</p>
|
|
<p>(6.7%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>0/30</p>
|
|
<p>(0%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">Peto OR 7.65 (0.47 to 125.22)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">70 more per 1000 (from 40 fewer to 170 more)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁⨁◯</p>
|
|
<p>MODERATE</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_13_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Intraoperative complications - blood loss (ml) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious risk of bias</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">55</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">55</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 228.82 lower (303.1 to 154.54 lower)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁⨁◯</p>
|
|
<p>MODERATE</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_15_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>3</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">186</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">188</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 9.34 higher (5.01 lower to 23.69 higher)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_h_niceng157er13.appf.tab3_1_1_1_5" id="hd_b_niceng157er13.appf.tab3_1_1_17_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Pain (change score) (follow-up 12 months; measured with: VAS scale; Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_1 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_2 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_3 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_4 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_5 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_6 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_1 hd_h_niceng157er13.appf.tab3_1_1_2_7 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_8 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">10</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_2 hd_h_niceng157er13.appf.tab3_1_1_2_9 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">12</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_10 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_3 hd_h_niceng157er13.appf.tab3_1_1_2_11 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 7.28 lower (24.1 lower to 9.54 higher)</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_4 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
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<p>LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab3_1_1_1_5 hd_b_niceng157er13.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.appf.tab3_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.appf.tab3_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl><dl class="bkr_refwrap"><dt>3</dt><dd><div id="niceng157er13.appf.tab3_3"><p class="no_margin">Downgraded by 1 or 2 increments because the point estimates varied widely across studies, unexplained by subgroup analysis</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobniceng157er13appftab4"><div id="niceng157er13.appf.tab4" class="table"><h3><span class="label">Table 16</span><span class="title">Clinical evidence profile: SuperPATH approach versus Posterior approach</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appf.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appf.tab4_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_niceng157er13.appf.tab4_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_niceng157er13.appf.tab4_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_niceng157er13.appf.tab4_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_niceng157er13.appf.tab4_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab4_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_niceng157er13.appf.tab4_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_niceng157er13.appf.tab4_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1" id="hd_h_niceng157er13.appf.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">No of studies</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1" id="hd_h_niceng157er13.appf.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Design</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1" id="hd_h_niceng157er13.appf.tab4_1_1_2_3" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Risk of bias</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1" id="hd_h_niceng157er13.appf.tab4_1_1_2_4" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Inconsistency</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1" id="hd_h_niceng157er13.appf.tab4_1_1_2_5" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Indirectness</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1" id="hd_h_niceng157er13.appf.tab4_1_1_2_6" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Imprecision</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1" id="hd_h_niceng157er13.appf.tab4_1_1_2_7" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Other considerations</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_2" id="hd_h_niceng157er13.appf.tab4_1_1_2_8" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">SuperPATH approach</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_2" id="hd_h_niceng157er13.appf.tab4_1_1_2_9" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Posterior approach</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_3" id="hd_h_niceng157er13.appf.tab4_1_1_2_10" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_3" id="hd_h_niceng157er13.appf.tab4_1_1_2_11" rowspan="1" colspan="1" style="text-align:center;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_h_niceng157er13.appf.tab4_1_1_1_5" id="hd_b_niceng157er13.appf.tab4_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 1 weeks; measured with: Barthel Index score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 6.21 higher (2.68 to 9.74 higher)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_5 hd_b_niceng157er13.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_h_niceng157er13.appf.tab4_1_1_1_5" id="hd_b_niceng157er13.appf.tab4_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 1 weeks; measured with: Harris Hip Score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 4.8 higher (3.01 to 6.59 higher)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_5 hd_b_niceng157er13.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_h_niceng157er13.appf.tab4_1_1_1_5" id="hd_b_niceng157er13.appf.tab4_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 1 years; measured with: Barthel Index score,; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.73 higher (2.49 lower to 3.95 higher)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁⨁◯◯</p>
|
|
<p>LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_5 hd_b_niceng157er13.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_h_niceng157er13.appf.tab4_1_1_1_5" id="hd_b_niceng157er13.appf.tab4_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">PROMs (follow-up 1 years; measured with: Harris Hip Score; Better indicated by higher values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.7 higher (0.14 lower to 1.54 higher)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_5 hd_b_niceng157er13.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_h_niceng157er13.appf.tab4_1_1_1_5" id="hd_b_niceng157er13.appf.tab4_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Dislocation (follow-up 12 months)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>1/46</p>
|
|
<p>(2.2%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>2/46</p>
|
|
<p>(4.3%)</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.5 (0.05 to 5.32)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">22 fewer per 1000 (from 41 fewer to 188 more)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_5 hd_b_niceng157er13.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_h_niceng157er13.appf.tab4_1_1_1_5" id="hd_b_niceng157er13.appf.tab4_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Length of stay (days) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 3.1 lower (4.35 to 1.85 lower)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁⨁◯</p>
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<p>MODERATE</p>
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|
</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_5 hd_b_niceng157er13.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_h_niceng157er13.appf.tab4_1_1_1_5" id="hd_b_niceng157er13.appf.tab4_1_1_13_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:top;">Surgery time (minutes) (Better indicated by lower values)</th></tr><tr><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_1 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_2 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomised trials</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_3 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_4 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_5 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_6 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>2</sup></td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_1 hd_h_niceng157er13.appf.tab4_1_1_2_7 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_8 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_2 hd_h_niceng157er13.appf.tab4_1_1_2_9 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">46</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_10 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_3 hd_h_niceng157er13.appf.tab4_1_1_2_11 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 2.9 lower (8.76 lower to 2.96 higher)</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_4 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁⨁◯◯</p>
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<p>LOW</p>
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</td><td headers="hd_h_niceng157er13.appf.tab4_1_1_1_5 hd_b_niceng157er13.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="niceng157er13.appf.tab4_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="niceng157er13.appf.tab4_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or by 2 increments if the confidence interval crossed both MIDs.</p></div></dd></dl></dl></div></div></div></article><article data-type="fig" id="figobniceng157er13appgfig1"><div id="niceng157er13.appg.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2052.%20Flow%20chart%20of%20health%20economic%20study%20selection%20for%20the%20guideline.&p=BOOKS&id=561418_niceng157er13appgf1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK561418/bin/niceng157er13appgf1.jpg" alt="Figure 52. Flow chart of health economic study selection for the guideline." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 52</span><span class="title">Flow chart of health economic study selection for the guideline</span></h3><div class="caption"><p>a) Non-relevant population, intervention, comparison, design or setting; non-English language</p><p>b) One study was applicable to both Q3.1 and Q3.2</p></div></div></article><article data-type="table-wrap" id="figobniceng157er13appitab1"><div id="niceng157er13.appi.tab1" class="table"><h3><span class="label">Table 17</span><span class="title">Studies excluded from the clinical review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appi.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appi.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusion reason</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anonymous 2018<a class="bibr" href="#niceng157er13.ref1" rid="niceng157er13.ref1"><sup>1</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Berstock 2014<a class="bibr" href="#niceng157er13.ref4" rid="niceng157er13.ref4"><sup>4</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Berstock 2015<a class="bibr" href="#niceng157er13.ref5" rid="niceng157er13.ref5"><sup>5</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bon 2019<a class="bibr" href="#niceng157er13.ref6" rid="niceng157er13.ref6"><sup>6</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bostrom 2005<a class="bibr" href="#niceng157er13.ref7" rid="niceng157er13.ref7"><sup>7</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Botha 1996<a class="bibr" href="#niceng157er13.ref8" rid="niceng157er13.ref8"><sup>8</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Cheng 2009<a class="bibr" href="#niceng157er13.ref11" rid="niceng157er13.ref11"><sup>11</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">De geest 2015<a class="bibr" href="#niceng157er13.ref17" rid="niceng157er13.ref17"><sup>17</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">De verteuil 2008<a class="bibr" href="#niceng157er13.ref18" rid="niceng157er13.ref18"><sup>18</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Della valle 2010<a class="bibr" href="#niceng157er13.ref19" rid="niceng157er13.ref19"><sup>19</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Den hartog 2016<a class="bibr" href="#niceng157er13.ref20" rid="niceng157er13.ref20"><sup>20</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dienstknecht 2013<a class="bibr" href="#niceng157er13.ref22" rid="niceng157er13.ref22"><sup>22</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dienstknecht 2014<a class="bibr" href="#niceng157er13.ref23" rid="niceng157er13.ref23"><sup>23</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dorr 2007<a class="bibr" href="#niceng157er13.ref24" rid="niceng157er13.ref24"><sup>24</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dutka 2007<a class="bibr" href="#niceng157er13.ref25" rid="niceng157er13.ref25"><sup>25</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eto 2017<a class="bibr" href="#niceng157er13.ref26" rid="niceng157er13.ref26"><sup>26</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fink 2012<a class="bibr" href="#niceng157er13.ref27" rid="niceng157er13.ref27"><sup>27</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Goosen 2011<a class="bibr" href="#niceng157er13.ref29" rid="niceng157er13.ref29"><sup>29</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Graves 2016<a class="bibr" href="#niceng157er13.ref30" rid="niceng157er13.ref30"><sup>30</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Greidanus 2013<a class="bibr" href="#niceng157er13.ref31" rid="niceng157er13.ref31"><sup>31</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gunther 2001<a class="bibr" href="#niceng157er13.ref32" rid="niceng157er13.ref32"><sup>32</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ha 2013<a class="bibr" href="#niceng157er13.ref33" rid="niceng157er13.ref33"><sup>33</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hendrickx 2014<a class="bibr" href="#niceng157er13.ref34" rid="niceng157er13.ref34"><sup>34</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Protocol</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Higgins 2015<a class="bibr" href="#niceng157er13.ref35" rid="niceng157er13.ref35"><sup>35</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hjorth 2017<a class="bibr" href="#niceng157er13.ref36" rid="niceng157er13.ref36"><sup>36</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Horwitz 1993<a class="bibr" href="#niceng157er13.ref37" rid="niceng157er13.ref37"><sup>37</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hozack 2015<a class="bibr" href="#niceng157er13.ref38" rid="niceng157er13.ref38"><sup>38</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Abstract</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hu 2012<a class="bibr" href="#niceng157er13.ref39" rid="niceng157er13.ref39"><sup>39</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inaba 2011<a class="bibr" href="#niceng157er13.ref40" rid="niceng157er13.ref40"><sup>40</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Jia 2018<a class="bibr" href="#niceng157er13.ref42" rid="niceng157er13.ref42"><sup>42</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Jolles 2004<a class="bibr" href="#niceng157er13.ref43" rid="niceng157er13.ref43"><sup>43</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Jolles 2006<a class="bibr" href="#niceng157er13.ref44" rid="niceng157er13.ref44"><sup>44</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Khan 2012<a class="bibr" href="#niceng157er13.ref45" rid="niceng157er13.ref45"><sup>45</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kucukdurmaz 2018<a class="bibr" href="#niceng157er13.ref46" rid="niceng157er13.ref46"><sup>46</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kwon 2006<a class="bibr" href="#niceng157er13.ref47" rid="niceng157er13.ref47"><sup>47</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Landgraeber 2013<a class="bibr" href="#niceng157er13.ref48" rid="niceng157er13.ref48"><sup>48</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lee 2015<a class="bibr" href="#niceng157er13.ref49" rid="niceng157er13.ref49"><sup>49</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Leuchte 2007<a class="bibr" href="#niceng157er13.ref50" rid="niceng157er13.ref50"><sup>50</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lin 2017<a class="bibr" href="#niceng157er13.ref51" rid="niceng157er13.ref51"><sup>51</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Luo 2016<a class="bibr" href="#niceng157er13.ref53" rid="niceng157er13.ref53"><sup>53</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Martin 2011<a class="bibr" href="#niceng157er13.ref54" rid="niceng157er13.ref54"><sup>54</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Matziolis 2011<a class="bibr" href="#niceng157er13.ref55" rid="niceng157er13.ref55"><sup>55</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meermans 2017<a class="bibr" href="#niceng157er13.ref57" rid="niceng157er13.ref57"><sup>57</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meneghini 2009<a class="bibr" href="#niceng157er13.ref58" rid="niceng157er13.ref58"><sup>58</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Migliorini 2019<a class="bibr" href="#niceng157er13.ref60" rid="niceng157er13.ref60"><sup>60</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Miller 2018<a class="bibr" href="#niceng157er13.ref61" rid="niceng157er13.ref61"><sup>61</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Miller 2018<a class="bibr" href="#niceng157er13.ref62" rid="niceng157er13.ref62"><sup>62</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Miller 2018<a class="bibr" href="#niceng157er13.ref63" rid="niceng157er13.ref63"><sup>63</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mouilhade 2011<a class="bibr" href="#niceng157er13.ref65" rid="niceng157er13.ref65"><sup>65</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mukka 2014<a class="bibr" href="#niceng157er13.ref66" rid="niceng157er13.ref66"><sup>66</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Muller 2011<a class="bibr" href="#niceng157er13.ref68" rid="niceng157er13.ref68"><sup>68</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Muller 2012<a class="bibr" href="#niceng157er13.ref67" rid="niceng157er13.ref67"><sup>67</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Murphy 2006<a class="bibr" href="#niceng157er13.ref69" rid="niceng157er13.ref69"><sup>69</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Musil 2008<a class="bibr" href="#niceng157er13.ref71" rid="niceng157er13.ref71"><sup>71</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Musil 2013<a class="bibr" href="#niceng157er13.ref70" rid="niceng157er13.ref70"><sup>70</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">O’brien 2005<a class="bibr" href="#niceng157er13.ref75" rid="niceng157er13.ref75"><sup>75</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ogonda 2005<a class="bibr" href="#niceng157er13.ref76" rid="niceng157er13.ref76"><sup>76</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ouyang 2018<a class="bibr" href="#niceng157er13.ref78" rid="niceng157er13.ref78"><sup>78</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Pai 1997<a class="bibr" href="#niceng157er13.ref79" rid="niceng157er13.ref79"><sup>79</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Parker 2002<a class="bibr" href="#niceng157er13.ref80" rid="niceng157er13.ref80"><sup>80</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Pospischill 2010<a class="bibr" href="#niceng157er13.ref83" rid="niceng157er13.ref83"><sup>83</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Putananon 2018<a class="bibr" href="#niceng157er13.ref84" rid="niceng157er13.ref84"><sup>84</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NMA- references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Queen 2014<a class="bibr" href="#niceng157er13.ref85" rid="niceng157er13.ref85"><sup>85</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Radoicic 2018<a class="bibr" href="#niceng157er13.ref86" rid="niceng157er13.ref86"><sup>86</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Repantis 2015<a class="bibr" href="#niceng157er13.ref89" rid="niceng157er13.ref89"><sup>89</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison. Incorrect interventions</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rittmeister 2006<a class="bibr" href="#niceng157er13.ref91" rid="niceng157er13.ref91"><sup>91</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rodriguez 2014<a class="bibr" href="#niceng157er13.ref92" rid="niceng157er13.ref92"><sup>92</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rosenlund 2014<a class="bibr" href="#niceng157er13.ref94" rid="niceng157er13.ref94"><sup>94</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Protocol</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rosenlund 2017<a class="bibr" href="#niceng157er13.ref93" rid="niceng157er13.ref93"><sup>93</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Protocol</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rykov 2016<a class="bibr" href="#niceng157er13.ref96" rid="niceng157er13.ref96"><sup>96</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Protocol</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Salineros 2007<a class="bibr" href="#niceng157er13.ref98" rid="niceng157er13.ref98"><sup>98</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sander 2011<a class="bibr" href="#niceng157er13.ref99" rid="niceng157er13.ref99"><sup>99</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Schwarze 2018<a class="bibr" href="#niceng157er13.ref100" rid="niceng157er13.ref100"><sup>100</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sendtner 2011<a class="bibr" href="#niceng157er13.ref101" rid="niceng157er13.ref101"><sup>101</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison. Incorrect interventions</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sharma 2006<a class="bibr" href="#niceng157er13.ref103" rid="niceng157er13.ref103"><sup>103</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Speranza 2007<a class="bibr" href="#niceng157er13.ref104" rid="niceng157er13.ref104"><sup>104</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison. Incorrect interventions</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Takada 2018<a class="bibr" href="#niceng157er13.ref105" rid="niceng157er13.ref105"><sup>105</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Talia 2018<a class="bibr" href="#niceng157er13.ref106" rid="niceng157er13.ref106"><sup>106</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Protocol</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Tanavalee 2006<a class="bibr" href="#niceng157er13.ref107" rid="niceng157er13.ref107"><sup>107</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Varela-Egocheaga 2010<a class="bibr" href="#niceng157er13.ref111" rid="niceng157er13.ref111"><sup>111</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Varela-Egocheaga 2013<a class="bibr" href="#niceng157er13.ref112" rid="niceng157er13.ref112"><sup>112</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate comparison</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wang 2018<a class="bibr" href="#niceng157er13.ref113" rid="niceng157er13.ref113"><sup>113</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Whatling 2008<a class="bibr" href="#niceng157er13.ref114" rid="niceng157er13.ref114"><sup>114</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wohlrab 2004<a class="bibr" href="#niceng157er13.ref117" rid="niceng157er13.ref117"><sup>117</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wohlrab 2008<a class="bibr" href="#niceng157er13.ref116" rid="niceng157er13.ref116"><sup>116</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Xu 2013<a class="bibr" href="#niceng157er13.ref119" rid="niceng157er13.ref119"><sup>119</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Xu 2017<a class="bibr" href="#niceng157er13.ref120" rid="niceng157er13.ref120"><sup>120</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Yamamoto 2017<a class="bibr" href="#niceng157er13.ref121" rid="niceng157er13.ref121"><sup>121</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Yan 2005<a class="bibr" href="#niceng157er13.ref122" rid="niceng157er13.ref122"><sup>122</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Yang 2009<a class="bibr" href="#niceng157er13.ref125" rid="niceng157er13.ref125"><sup>125</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Yang 2012<a class="bibr" href="#niceng157er13.ref123" rid="niceng157er13.ref123"><sup>123</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Yue 2015<a class="bibr" href="#niceng157er13.ref126" rid="niceng157er13.ref126"><sup>126</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review - references individually checked</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Zhang 2006<a class="bibr" href="#niceng157er13.ref127" rid="niceng157er13.ref127"><sup>127</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Zheng 2018<a class="bibr" href="#niceng157er13.ref129" rid="niceng157er13.ref129"><sup>129</sup></a></td><td headers="hd_h_niceng157er13.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not in English</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appitab2"><div id="niceng157er13.appi.tab2" class="table"><h3><span class="label">Table 18</span><span class="title">Studies excluded from the health economic review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appi.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appi.tab2_lrgtbl__"><table><thead><tr><th id="hd_h_niceng157er13.appi.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reference</th><th id="hd_h_niceng157er13.appi.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reason for exclusion</th></tr></thead><tbody><tr><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Coyle 2008<a class="bibr" href="#niceng157er13.ref14" rid="niceng157er13.ref14"><sup>14</sup></a></td><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was excluded as it compared the length of incision with all surgery approaches meta-analysed together</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">de Verteuil 2008<a class="bibr" href="#niceng157er13.ref18" rid="niceng157er13.ref18"><sup>18</sup></a></td><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was excluded as it compared the length of incision with all surgery approaches meta-analysed together</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gofton 2016<a class="bibr" href="#niceng157er13.ref28" rid="niceng157er13.ref28"><sup>28</sup></a></td><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was assessed as partially applicable with very serious limitations as it may have been a US study (unclear) and it only reported costs in percentages.</td></tr><tr><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Martin 2011<a class="bibr" href="#niceng157er13.ref54" rid="niceng157er13.ref54"><sup>54</sup></a></td><td headers="hd_h_niceng157er13.appi.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was assessed as having very serious limitations as a cost figure was presented without any described methodology of calculations</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobniceng157er13appjtab1"><div id="niceng157er13.appj.tab1" class="table"><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK561418/table/niceng157er13.appj.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__niceng157er13.appj.tab1_lrgtbl__"><table><tbody><tr><th id="hd_b_niceng157er13.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PICO question</th><td headers="hd_b_niceng157er13.appj.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Population: Patients receiving an elective primary total hip replacement</p>
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<p>Intervention(s): Direct anterior, direct superior or superPATH surgical approaches to the hip</p>
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<p>Comparison: Posterior or anterolateral approaches to the hip</p>
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<p>Outcome(s): Patient reported outcome measures including health related quality of life, Surgical time, Length of stay, rates of complications including the risk of nerve injury and/or neuropraxia, infection, dislocation and problems relating to wound healing</p>
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</td></tr><tr><th id="hd_b_niceng157er13.appj.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study design</th><td headers="hd_b_niceng157er13.appj.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Multicentre Randomised controlled trial comparing one or more interventions to one of the current standard practices (comparators)</td></tr><tr><th id="hd_b_niceng157er13.appj.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Other details</th><td headers="hd_b_niceng157er13.appj.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NICE evidence review raised concerns over the high rates of nerve injury and/or neuropraxia reported in previous studies examining outcomes after the direct anterior approach. The committee also had concerns about infected and wound healing problems related to some of the newer approaches. The committee felt it essential that these outcomes be measured as secondary endpoints in any trial but that a PROM / Health related quality of life measure should be the primary outcome.</td></tr></tbody></table></div></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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