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preserveAspectRatio="none"><path fill="none" stroke="#000" stroke-width="36" stroke-linecap="round" style="fill:#FFF" d="m320,350a153,153 0 1,0-2,2l170,170m-91-117 110,110-26,26-110-110"></path></svg></a><a id="jr-fip-done" class="wsprkl btn" title="Dismiss find">✘</a></nav><nav id="jr-fip-info-p"><a id="jr-fip-prev" class="wsprkl btn" title="Jump to previuos match">◀</a><button id="jr-fip-matches">no matches yet</button><a id="jr-fip-next" class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style"><div class="fm-sec bkr_bottom_sep"><div class="bkr_thumb"><a href="https://www.nice.org.uk" title="National Institute for Health and Care Excellence (NICE)" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-niceng142er10-lrg.png" alt="Cover of Evidence review: Service provision: identifying the need for additional services; timing and frequency of review of services" /></a></div><div class="bkr_bib"><h1 id="_NBK558772_"><span itemprop="name">Evidence review: Service provision: identifying the need for additional services; timing and frequency of review of services</span></h1><div class="subtitle">End of life care for adults: service delivery</div><p><b>Evidence review J</b></p><p><i>NICE Guideline, No. 142</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">National Guideline Centre (UK)</span>.</p><div class="half_rhythm">London: <a href="https://www.nice.org.uk" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">National Institute for Health and Care Excellence (NICE)</span></a>; <span itemprop="datePublished">2019 Oct</span>.<div class="small">ISBN-13: <span itemprop="isbn">978-1-4731-3560-4</span></div></div><div><a href="/books/about/copyright/">Copyright</a> © NICE 2019.</div></div><div class="bkr_clear"></div></div><div id="ch10.s1"><h2 id="_ch10_s1_">1. Review of service provision (identifying the need of additional services; timing and frequency of review of service provision)</h2><div id="ch10.s1.1"><h3>1.1. Review question 1: What is the best method/service to review service provision and identify when additional services may be required in people thought to be entering their last year of life?</h3></div><div id="ch10.s1.2"><h3>1.2. Review question 2: When and how frequently should service need provision be reviewed in people thought to be in their last year of life?</h3></div><div id="ch10.s1.3"><h3>1.3. Introduction</h3><p>It is well recognised that planning services with people in the last year of life and their carers is key to a good outcome at the end of life. The identification of additional services that may be required or indeed discontinued should be based on a holistic needs assessment that is responsive to change as things change. It is reasonable to assume that needs between people vary widely and generalisations cannot be made.</p><p>Too many services involved can be as problematic as too few. It is just as important to review when existing services are no longer required. Patient’s needs and the needs of their carer’s/loved ones may differ in intensity at different times, and need to be assessed separately.</p><p>Additional services are those required in addition to the core palliative care services provided in any particular location. For people at home, core palliative care is provided by the general practice team, and community nursing as required. In acute hospital, core palliative care is provided by the ward-based health and social care team.</p><p>The additional services that may be required range widely, from additional nursing, social care, and allied health professional support, to welfare and benefits advice, specialist palliative care, spiritual care and other specialist support for example heart failure nurse, community diabetes, dementia nursing support, and specialist psychological support. Service configurations may also vary widely, for example allied health professionals may provide services from services based within general practice, community nursing or hospice/community specialist palliative care. Eligibility and discharge criteria for additional services should be available, and based on current level of need identified through a holistic care assessment.</p></div><div id="ch10.s1.4"><h3>1.4. PICO table</h3><p>For full details see the review protocol in <a href="#ch10.appa">appendix A</a>.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch10tab1"><a href="/books/NBK558772/table/ch10.tab1/?report=objectonly" target="object" title="Table 1" class="img_link icnblk_img figpopup" rid-figpopup="figch10tab1" rid-ob="figobch10tab1"><img class="small-thumb" src="/books/NBK558772/table/ch10.tab1/?report=thumb" src-large="/books/NBK558772/table/ch10.tab1/?report=previmg" alt="Table 1. PICO characteristics of review question 1." /></a><div class="icnblk_cntnt"><h4 id="ch10.tab1"><a href="/books/NBK558772/table/ch10.tab1/?report=objectonly" target="object" rid-ob="figobch10tab1">Table 1</a></h4><p class="float-caption no_bottom_margin">PICO characteristics of review question 1. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch10tab2"><a href="/books/NBK558772/table/ch10.tab2/?report=objectonly" target="object" title="Table 2" class="img_link icnblk_img figpopup" rid-figpopup="figch10tab2" rid-ob="figobch10tab2"><img class="small-thumb" src="/books/NBK558772/table/ch10.tab2/?report=thumb" src-large="/books/NBK558772/table/ch10.tab2/?report=previmg" alt="Table 2. PICO characteristics of review question 2." /></a><div class="icnblk_cntnt"><h4 id="ch10.tab2"><a href="/books/NBK558772/table/ch10.tab2/?report=objectonly" target="object" rid-ob="figobch10tab2">Table 2</a></h4><p class="float-caption no_bottom_margin">PICO characteristics of review question 2. </p></div></div></div><div id="ch10.s1.5"><h3>1.5. Clinical evidence</h3><div id="ch10.s1.5.1"><h4>1.5.1. Included studies</h4><p>A search was conducted for randomised trials or non-randomised comparative studies on service models (or service components) enabling the identification of the need for additional services, and the timing and frequency of review of service provision for people in their last year of life.</p><p>No relevant clinical studies were identified for this review.</p></div><div id="ch10.s1.5.2"><h4>1.5.2. Excluded studies</h4><p>See the excluded studies list in <a href="#ch10.apph">appendix H</a>.</p></div></div><div id="ch10.s1.6"><h3>1.6. Economic evidence</h3><div id="ch10.s1.6.1"><h4>1.6.1. Included studies</h4><p>No relevant health economic studies were identified.</p></div><div id="ch10.s1.6.2"><h4>1.6.2. Excluded studies</h4><p>No health economic studies that were relevant to this question were excluded due to assessment of limited applicability or methodological limitations.</p><p>See also the health economic study selection flow chart in <a href="#ch10.appg">appendix G</a>.</p></div><div id="ch10.s1.6.3"><h4>1.6.3. Unit costs</h4><p><a class="figpopup" href="/books/NBK558772/table/ch10.tab3/?report=objectonly" target="object" rid-figpopup="figch10tab3" rid-ob="figobch10tab3">Table 3</a> reports the unit cost of staff time for some health care professionals who may undertake a review of a person’s holistic needs with the person in the last year of life, to determine whether they require any changes to the end-of-life care services they receive. The cost of patient contact as opposed to per working hour has been reported where available.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch10tab3"><a href="/books/NBK558772/table/ch10.tab3/?report=objectonly" target="object" title="Table 3" class="img_link icnblk_img figpopup" rid-figpopup="figch10tab3" rid-ob="figobch10tab3"><img class="small-thumb" src="/books/NBK558772/table/ch10.tab3/?report=thumb" src-large="/books/NBK558772/table/ch10.tab3/?report=previmg" alt="Table 3. UK costs of staff time for health care professionals who might undertake reviews of a person’s end-of-life care needs." /></a><div class="icnblk_cntnt"><h4 id="ch10.tab3"><a href="/books/NBK558772/table/ch10.tab3/?report=objectonly" target="object" rid-ob="figobch10tab3">Table 3</a></h4><p class="float-caption no_bottom_margin">UK costs of staff time for health care professionals who might undertake reviews of a person’s end-of-life care needs. </p></div></div></div></div><div id="ch10.s1.7"><h3>1.7. Resource costs</h3><p>Recommendations made based on this review (see section <b>Error! Reference source not found.</b>) are not expected to have a substantial impact on resources.</p></div><div id="ch10.s1.8"><h3>1.8. Evidence statements</h3><div id="ch10.s1.8.1"><h4>1.8.1. Clinical evidence statements</h4><p>No relevant published evidence was identified.</p></div><div id="ch10.s1.8.2"><h4>1.8.2. Health economic evidence statements</h4><p>No relevant economic evaluations were identified.</p></div></div><div id="ch10.s1.9"><h3>1.9. The committee’s discussion of the evidence</h3><div id="ch10.s1.9.1"><h4>1.9.1. Interpreting the evidence</h4><p>The committee identified quality of life, preferred place of care and preferred place of death as the critical outcomes. The following outcomes were identified as important for decision making and focus on the impact and use of health resources as well as the impact on the patient; length of survival, length of hospital stay, hospitalisation, number of hospital visits, number of visits to accident and emergency, number of unscheduled admissions, use of community services, avoidable/inappropriate admissions to ICU, inappropriate attempts at cardiopulmonary resuscitation and staff, patient and carer satisfaction.</p><p>See tables 7 and 8 in the <a href="/books/NBK558772/bin/bm1.pdf">Methods</a> chapter for a detailed explanation of why the committee selected these outcomes.</p><p>No relevant clinical studies were identified; therefore no evidence was available for any of these outcomes.</p><div id="ch10.s1.9.1.1"><h5>1.9.1.1. The quality of the evidence</h5><p>No relevant clinical studies were identified for this review.</p></div><div id="ch10.s1.9.1.2"><h5>1.9.1.2. Benefits and harms</h5><p>No relevant clinical studies were identified for this review. However, the Committee felt that a consensus recommendation in this area was warranted as it is important that people receive the right care at the right time. If care is not reviewed then people may stay on treatments that are unnecessary and not receive the ones that are now needed</p><p>The Committee agreed to recommend that the needs of people in the last year of life should be assessed when required, for example at transition points. End of life treatment and care issues should be discussed whenever people wish to do so, and the timing of discussion should take into account the person’s current communication ability, cognitive status and mental capacity. The Committee also agreed to formulate a research recommendation to encourage further research regarding the modality, timing and frequency of review of service provision in people in the last year of life.</p></div></div><div id="ch10.s1.9.2"><h4>1.9.2. Cost effectiveness and resource use</h4><p>Most End of Life care services are provided to help improve the quality of care and maintain quality of life of people thought to be nearing the end of life. Some of the services provided may also reduce costs to the NHS, for example, by reducing the number of inappropriate emergency admissions or reducing the proportion of deaths occurring in hospitals. In order to provide the level of services that meet the needs of a patient, the patient’s needs must be assessed; ideally through a holistic needs assessment. Patient’s needs are likely to vary over the duration of their last year of life. To ensure the levels of services provided continuously meet the needs of the patient their needs will need to be regularly reviewed. How often their needs are reviewed will depend on how quickly the needs of the patient change over time.</p><p>Determining the interval between reassessment of patient and carer needs requires careful consideration. Reviewing too early could mean that a patient’s needs have not changed and therefore reviewing their services is an inefficient use of their time, and service resources. Reviewing too late could mean that the patient and their family have been struggling with unmet needs, and possibly needing to access care in an unplanned, and therefore inefficient, way. To ensure that patient and NHS resources are used as efficiently as possible, it would seem appropriate to determine when to review patients’ needs on a patient by patient basis, tailoring the service delivery to meet the individual needs of the patient.</p><p>The committee discussed the balance of when to review services and the feeling from the group was that currently it is much more likely that patient needs and services are not reviewed enough and leading to unmet needs of patients. Although theoretically patients could be reviewed too often, in reality this rarely happens.</p><p>No economic evidence was identified therefore it was not possible to determine the cost effectiveness of reviewing patients’ needs for any time intervals. However, the committee considered cost effectiveness when making their consensus recommendations. Instead of selecting a timespan for how often needs should be reviewed, the committee felt it would be a better and more cost effective use of resources for patients to have assessments of their needs only when required, for example at periods of transition.</p></div><div id="ch10.s1.9.3"><h4>1.9.3. Other factors the committee took into account</h4><p>The Committee acknowledged that for some conditions the identification of transition points at which to review service provision could be difficult, for example in people with dementia and frailty. They were aware of national tools for the identification of transition point specific for palliative care, for example OACC and GSF. However they expressed their concern on the absence of published research on the impact of these tools on service provision.</p><p>The Committee stressed that patients may not initiate discussions about end of life care, dying and their concerns, often expecting the clinicians to raise these issues first.</p><p>In line with the recommendations on good communication and the importance of avoiding duplication of care the committee noted that the content and the extent of the reviews and repeat assessments undertaken should be tailored to the individual and a full assessment may not always be necessary.</p></div></div></div><div id="ch10.rl.r1"><h2 id="_ch10_rl_r1_">References</h2><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="ch10.ref1">Curtis
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L, Burns
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A. Unit costs of health & social care 2016. Canterbury. University of Kent Personal Social Services Research Unit, 2016.</div></dd></dl><dl class="bkr_refwrap"><dt>2.</dt><dd><div class="bk_ref" id="ch10.ref2">Edwards
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D, Carrier
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J, Gillen
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E, Hawker
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C, Sutton
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J, Kelly
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D. Factors influencing the provision of end of life care for adolescents and young adults with advanced cancer: A scoping review protocol. JBI Database Of Systematic Reviews And Implementation Reports. 2013; 11(7):386–399</div></dd></dl><dl class="bkr_refwrap"><dt>3.</dt><dd><div class="bk_ref" id="ch10.ref3">Hu
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W, Yasui
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Y, White
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J, Winget
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M. Aggressiveness of end-of-life care for patients with colorectal cancer in Salberta, Canada: 2006-2009. Journal of Pain and Symptom Management. 2014; 47(2):231–244 [<a href="https://pubmed.ncbi.nlm.nih.gov/23870414" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23870414</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>4.</dt><dd><div class="bk_ref" id="ch10.ref4">Jacob
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S, Wong
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K, Delaney
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GP, Adams
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P, Barton
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MB. Estimation of an optimal utilisation rate for palliative radiotherapy in newly diagnosed cancer patients. Clinical Oncology. 2010; 22(1):56–64 [<a href="https://pubmed.ncbi.nlm.nih.gov/19969443" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19969443</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>5.</dt><dd><div class="bk_ref" id="ch10.ref5">Lam
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M, Lam
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HR, Agarwal
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A, Lam
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H, Chow
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R, Chow
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S
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et al. Barriers to home death for canadian cancer patients: A literature review. Journal of Pain Management. 2017; 10(1):107–116</div></dd></dl><dl class="bkr_refwrap"><dt>6.</dt><dd><div class="bk_ref" id="ch10.ref6">Miller
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SC, Lima
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JC, Intrator
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O, Martin
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E, Bull
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J, Hanson
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LC. Specialty palliative care consultations for nursing home residents with dementia. Journal of Pain and Symptom Management. 2017; 54(1):9–16.e15 [<a href="/pmc/articles/PMC5663286/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5663286</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28438589" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28438589</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>7.</dt><dd><div class="bk_ref" id="ch10.ref7">National Institute for Health and Care Excellence. Developing NICE guidelines: the manual. London. National Institute for Health and Care Excellence, 2014. Available from: <a href="http://www.nice.org.uk/article/PMG20/chapter/1%20Introduction%20and%20overview" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.nice.org.uk<wbr style="display:inline-block"></wbr>​/article/PMG20/chapter<wbr style="display:inline-block"></wbr>​/1%20Introduction%20and%20overview</a> [<a href="https://pubmed.ncbi.nlm.nih.gov/26677490" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26677490</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>8.</dt><dd><div class="bk_ref" id="ch10.ref8">Schenker
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Y, Bahary
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N, Claxton
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R, Childers
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J, Chu
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E, Kavalieratos
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D
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et al. A pilot trial of early specialty palliative care for patients with advanced pancreatic cancer: challenges encountered and lessons learned. Journal of Palliative Medicine. 2017; Epublication [<a href="/pmc/articles/PMC5757080/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC5757080</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/28772092" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 28772092</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>9.</dt><dd><div class="bk_ref" id="ch10.ref9">White
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KR, Cochran
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CE, Patel
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UB. Hospital provision of end-of-life services: who, what, and where?
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Medical Care. 2002; 40(1):17–25 [<a href="https://pubmed.ncbi.nlm.nih.gov/11748423" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11748423</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>10.</dt><dd><div class="bk_ref" id="ch10.ref10">Wilson
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C, Roy
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D. Relationship between physical therapy, occupational therapy, palliative care consultations, and hospital length of stay. Journal of Acute Care Physical Therapy. 2017; 8(3):106–112</div></dd></dl><dl class="bkr_refwrap"><dt>11.</dt><dd><div class="bk_ref" id="ch10.ref11">Yilmaz
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MC, Emiroglu
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ON. The need assessment of MI patients in discharge planning and home-health care: A sample from Turkey. Internet Journal of Advanced Nursing Practice. 2005; 7(2)</div></dd></dl></dl></div><div id="appendixesappgroup10"><h2 id="_appendixesappgroup10_">Appendices</h2><div id="ch10.appa"><h3>Appendix A. Review protocols</h3><p id="ch10.appa.tab1"><a href="/books/NBK558772/table/ch10.appa.tab1/?report=objectonly" target="object" rid-ob="figobch10appatab1" class="figpopup">Table 4. Review protocol for what is the best method/service to review service provision and identify when additional services may be required in people thought to be entering their last year of life?</a></p><p id="ch10.appa.tab2"><a href="/books/NBK558772/table/ch10.appa.tab2/?report=objectonly" target="object" rid-ob="figobch10appatab2" class="figpopup">Table 5. Review protocol for when and how frequently should service need provision be reviewed in people thought to be in their last year of life?</a></p><p id="ch10.appa.tab3"><a href="/books/NBK558772/table/ch10.appa.tab3/?report=objectonly" target="object" rid-ob="figobch10appatab3" class="figpopup">Table 6. Health economic review protocol</a></p></div><div id="ch10.appb"><h3>Appendix B. Literature search strategies</h3><p>The literature searches for this review are detailed below and complied with the methodology outlined in Developing NICE guidelines: the manual 2014, updated 2017 <a href="https://www.nice.org.uk/guidance/pmg20/resources/developing-nice-guidelines-the-manual-pdf-72286708700869" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www.nice.org.uk/guidance/pmg20/resources/developing-nice-guidelines-the-manual-pdf-72286708700869</a></p><p><i>For more detailed information, please see the</i>
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<a href="/books/NBK558772/bin/bm1.pdf">Methodology</a>
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<i>Review</i>.</p><div id="ch10.appb.s1"><h4>B.1. Clinical search literature search strategy</h4><p>Searches for were constructed using a PICO framework where population (P) terms were combined with Intervention (I) and in some cases Comparison (C) terms. Outcomes (O) are rarely used in search strategies for interventions as these concepts may not be well described in title, abstract or indexes and therefore difficult to retrieve. Search filters were applied to the search where appropriate.</p><p id="ch10.appb.tab1"><a href="/books/NBK558772/table/ch10.appb.tab1/?report=objectonly" target="object" rid-ob="figobch10appbtab1" class="figpopup">Table 7. Database date parameters and filters used</a></p><p id="ch10.appb.tab2"><a href="/books/NBK558772/table/ch10.appb.tab2/?report=objectonly" target="object" rid-ob="figobch10appbtab2" class="figpopup">Medline (Ovid) search terms</a></p><p id="ch10.appb.tab3"><a href="/books/NBK558772/table/ch10.appb.tab3/?report=objectonly" target="object" rid-ob="figobch10appbtab3" class="figpopup">Embase (Ovid) search terms</a></p><p id="ch10.appb.tab4"><a href="/books/NBK558772/table/ch10.appb.tab4/?report=objectonly" target="object" rid-ob="figobch10appbtab4" class="figpopup">Cochrane Library (Wiley) search terms</a></p><p id="ch10.appb.tab5"><a href="/books/NBK558772/table/ch10.appb.tab5/?report=objectonly" target="object" rid-ob="figobch10appbtab5" class="figpopup">CINAHL (EBSCO) search terms</a></p><p id="ch10.appb.tab6"><a href="/books/NBK558772/table/ch10.appb.tab6/?report=objectonly" target="object" rid-ob="figobch10appbtab6" class="figpopup">PsycINFO (ProQuest) search terms</a></p><p id="ch10.appb.tab7"><a href="/books/NBK558772/table/ch10.appb.tab7/?report=objectonly" target="object" rid-ob="figobch10appbtab7" class="figpopup">HMIC (Ovid) search terms</a></p><p id="ch10.appb.tab8"><a href="/books/NBK558772/table/ch10.appb.tab8/?report=objectonly" target="object" rid-ob="figobch10appbtab8" class="figpopup">SPP (Ovid) search terms</a></p><p id="ch10.appb.tab9"><a href="/books/NBK558772/table/ch10.appb.tab9/?report=objectonly" target="object" rid-ob="figobch10appbtab9" class="figpopup">ASSIA (ProQuest) search terms</a></p></div><div id="ch10.appb.s2"><h4>B.2. Health Economics literature search strategy</h4><p>Health economic evidence was identified by conducting a broad search relating to end of life care in NHS Economic Evaluation Database (NHS EED – this ceased to be updated after March 2015) and the Health Technology Assessment database (HTA) with no date restrictions. NHS EED and HTA databases are hosted by the Centre for Research and Dissemination (CRD). Additional searches were run on Medline and Embase for health economics, economic modelling and quality of life studies.</p><p id="ch10.appb.tab10"><a href="/books/NBK558772/table/ch10.appb.tab10/?report=objectonly" target="object" rid-ob="figobch10appbtab10" class="figpopup">Table 8. Database date parameters and filters used</a></p><p id="ch10.appb.tab11"><a href="/books/NBK558772/table/ch10.appb.tab11/?report=objectonly" target="object" rid-ob="figobch10appbtab11" class="figpopup">Medline (Ovid) search terms</a></p><p id="ch10.appb.tab12"><a href="/books/NBK558772/table/ch10.appb.tab12/?report=objectonly" target="object" rid-ob="figobch10appbtab12" class="figpopup">Embase (Ovid) search terms</a></p><p id="ch10.appb.tab13"><a href="/books/NBK558772/table/ch10.appb.tab13/?report=objectonly" target="object" rid-ob="figobch10appbtab13" class="figpopup">NHS EED and HTA (CRD) search terms</a></p></div></div><div id="ch10.appc"><h3>Appendix C. Clinical evidence selection</h3><p id="ch10.appc.fig1"><a href="/books/NBK558772/figure/ch10.appc.fig1/?report=objectonly" target="object" rid-ob="figobch10appcfig1" class="figpopup">Figure 1. Flow chart of clinical study selection for the review of review of service provision</a></p></div><div id="ch10.appd"><h3>Appendix D. Clinical evidence tables</h3><p>None.</p></div><div id="ch10.appe"><h3>Appendix E. Forest plots</h3><p>None.</p></div><div id="ch10.appf"><h3>Appendix F. GRADE tables</h3><p>None.</p></div><div id="ch10.appg"><h3>Appendix G. Health economic evidence selection</h3><p id="ch10.appg.fig1"><a href="/books/NBK558772/figure/ch10.appg.fig1/?report=objectonly" target="object" rid-ob="figobch10appgfig1" class="figpopup">Figure 2. Flow chart of health economic study selection for the guideline</a></p></div><div id="ch10.apph"><h3>Appendix H. Excluded studies</h3><div id="ch10.apph.s1"><h4>H.1. Excluded clinical studies</h4><p id="ch10.apph.tab1"><a href="/books/NBK558772/table/ch10.apph.tab1/?report=objectonly" target="object" rid-ob="figobch10apphtab1" class="figpopup">Table 9. Studies excluded from the clinical review</a></p></div><div id="ch10.apph.s2"><h4>H.2. Excluded health economic studies</h4><p>No economic studies were excluded for this review.</p></div></div><div id="ch10.appi"><h3>Appendix I. Research recommendations</h3><p>
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<b>RR3 What are the benefits of planned regular community-based reviews versus as required review of non-cancer patients in last year of life?</b>
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</p><p>
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<b>
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<i>Why this is important</i>
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</b>
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</p><p>There is little relevant research evidence for the optimum frequency of review of patients with progressive non-cancer conditions who have entered the last year of life. Many of the studies attempted in this area have been conducted in other countries where the healthcare systems are very different from the UK. ‘Usual care’ for non-cancer conditions tends to provide demand-led review by specialists and primary care staff. This may be appropriate if patients are well supported at home or in care settings, but could lead to unrecognised deterioration in symptoms or functioning; and place people at risk of crises and unplanned hospital admissions if they are living alone and/or with little professional support. A policy of regular planned reviews of patients in their usual place of residence could improve symptom management, maintain better level of functioning, prevent crises and may pre-empt emergency hospital visits and admission; but conversely they could impose unnecessary burdens on the patient, family and the healthcare system. This research would study non-cancer patients receiving usual care (with or without any concurrent specialist level care), and assess their outcomes against different levels of frequency of planned specialist reviews in the community.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch10appitab1"><a href="/books/NBK558772/table/ch10.appi.tab1/?report=objectonly" target="object" title="Table" class="img_link icnblk_img figpopup" rid-figpopup="figch10appitab1" rid-ob="figobch10appitab1"><img class="small-thumb" src="/books/NBK558772/table/ch10.appi.tab1/?report=thumb" src-large="/books/NBK558772/table/ch10.appi.tab1/?report=previmg" alt="Image " /></a><div class="icnblk_cntnt"><h4 id="ch10.appi.tab1"><a href="/books/NBK558772/table/ch10.appi.tab1/?report=objectonly" target="object" rid-ob="figobch10appitab1">Table</a></h4><p class="float-caption no_bottom_margin">
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<i>What are the benefits of planned regular reviews versus as required review of non-cancer patients in last year of life?</i>
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Population: People entering the last year of life with a chronic progressive disease such as COPD, renal failure or dementia. For <a href="/books/NBK558772/table/ch10.appi.tab1/?report=objectonly" target="object" rid-ob="figobch10appitab1">(more...)</a></p></div></div></div></div></div><div class="fm-sec"><div><p>Final</p></div><div><p>Evidence review</p><p>Developed by the National Guideline Centre, hosted by the Royal College of Physicians</p></div><div><p><b>Disclaimer</b>: The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The recommendations in this guideline are not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian.</p><p>Local commissioners and/or providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties.</p><p>NICE guidelines cover health and care in England. Decisions on how they apply in other UK countries are made by ministers in the <a href="http://wales.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Welsh Government</a>, <a href="http://www.scotland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Scottish Government</a>, and <a href="http://www.northernireland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Northern Ireland Executive</a>. All NICE guidance is subject to regular review and may be updated or withdrawn.</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> © NICE 2019.</div><div class="small"><span class="label">Bookshelf ID: NBK558772</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32614557" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">32614557</a></span></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article><article data-type="table-wrap" id="figobch10tab1"><div id="ch10.tab1" class="table"><h3><span class="label">Table 1</span><span class="title">PICO characteristics of review question 1</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.tab1_lrgtbl__"><table><tbody><tr><th id="hd_b_ch10.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><td headers="hd_b_ch10.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adults (aged over 18 or over) with progressive life-limiting conditions thought to be entering the last year of life.</td></tr><tr><th id="hd_b_ch10.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Interventions</th><td headers="hd_b_ch10.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l1"><li id="ch10.lt1" class="half_rhythm"><div>Method/service to review service provision and identify when additional services may be required in people thought to be entering their last year of life</div></li></ul>
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Combinations of methods/services to review service provision and identify when additional services may be required in people thought to be entering their last year of life</td></tr><tr><th id="hd_b_ch10.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Comparisons</th><td headers="hd_b_ch10.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l2"><li id="ch10.lt2" class="half_rhythm"><div>To each other</div></li><li id="ch10.lt3" class="half_rhythm"><div>No standardised method/service to review service provision and identify when additional services may be required</div></li></ul></td></tr><tr><th id="hd_b_ch10.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes</th><td headers="hd_b_ch10.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CRITICAL
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<dl id="ch10.l3" class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt4"><p class="no_top_margin">Quality of life (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt5"><p class="no_top_margin">Preferred and actual place of death (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt6"><p class="no_top_margin">Preferred and actual place of care (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt7"><p class="no_top_margin">Length of survival (Continuous)</p></dd></dl></dl>
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IMPORTANT
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<dl id="ch10.l4" class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt8"><p class="no_top_margin">Length of survival (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt9"><p class="no_top_margin">Length of stay (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt10"><p class="no_top_margin">Hospitalisation (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt11"><p class="no_top_margin">Number of hospital visits (Continuous/Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt12"><p class="no_top_margin">Number of visits to accident and emergency (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt13"><p class="no_top_margin">Number of unscheduled admissions (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt14"><p class="no_top_margin">Use of community services (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt15"><p class="no_top_margin">Avoidable/inappropriate admissions to ICU (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt16"><p class="no_top_margin">Inappropriate attempts at cardiopulmonary resuscitation (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt17"><p class="no_top_margin">Staff satisfaction (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt18"><p class="no_top_margin">Patient/carer reported outcomes (satisfaction) (Continuous)</p></dd></dl></dl></td></tr><tr><th id="hd_b_ch10.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study design</th><td headers="hd_b_ch10.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l5"><li id="ch10.lt19" class="half_rhythm"><div>Systematic reviews</div></li><li id="ch10.lt20" class="half_rhythm"><div>RCTs</div></li><li id="ch10.lt21" class="half_rhythm"><div>Non-randomised comparative studies, including before and after studies and interrupted-time series</div></li></ul></td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10tab2"><div id="ch10.tab2" class="table"><h3><span class="label">Table 2</span><span class="title">PICO characteristics of review question 2</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.tab2_lrgtbl__"><table><tbody><tr><th id="hd_b_ch10.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><td headers="hd_b_ch10.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adults (aged over 18 or over) with progressive life-limiting conditions thought to be entering the last year of life.</td></tr><tr><th id="hd_b_ch10.tab2_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Interventions</th><td headers="hd_b_ch10.tab2_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Timing/frequency to review service provision in people thought to be entering their last year of life</td></tr><tr><th id="hd_b_ch10.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Comparisons</th><td headers="hd_b_ch10.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l6"><li id="ch10.lt22" class="half_rhythm"><div>To each other</div></li><li id="ch10.lt23" class="half_rhythm"><div>No standardised timing/frequency to review service provision</div></li></ul></td></tr><tr><th id="hd_b_ch10.tab2_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes</th><td headers="hd_b_ch10.tab2_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CRITICAL
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<dl id="ch10.l7" class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt24"><p class="no_top_margin">Quality of life (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt25"><p class="no_top_margin">Preferred and actual place of death (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt26"><p class="no_top_margin">Preferred and actual place of care (Dichotomous)</p></dd></dl></dl>
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IMPORTANT
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<dl id="ch10.l8" class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt27"><p class="no_top_margin">Length of survival (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt28"><p class="no_top_margin">Length of stay (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt29"><p class="no_top_margin">Hospitalisation (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt30"><p class="no_top_margin">Number of hospital visits (Continuous/Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt31"><p class="no_top_margin">Number of visits to accident and emergency (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt32"><p class="no_top_margin">Number of unscheduled admissions (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt33"><p class="no_top_margin">Use of community services (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt34"><p class="no_top_margin">Avoidable/inappropriate admissions to ICU (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt35"><p class="no_top_margin">Inappropriate attempts at cardiopulmonary resuscitation (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt36"><p class="no_top_margin">Staff satisfaction (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch10.lt37"><p class="no_top_margin">Patient/carer reported outcomes (satisfaction) (Continuous)</p></dd></dl></dl></td></tr><tr><th id="hd_b_ch10.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study design</th><td headers="hd_b_ch10.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l9"><li id="ch10.lt38" class="half_rhythm"><div>Systematic reviews</div></li><li id="ch10.lt39" class="half_rhythm"><div>RCTs</div></li><li id="ch10.lt40" class="half_rhythm"><div>Non-randomised comparative studies, including before and after studies and interrupted-time series</div></li></ul></td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10tab3"><div id="ch10.tab3" class="table"><h3><span class="label">Table 3</span><span class="title">UK costs of staff time for health care professionals who might undertake reviews of a person’s end-of-life care needs</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.tab3_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch10.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Staff Member</th><th id="hd_h_ch10.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Unit Cost of Staff Time<sup>(a)</sup></th></tr></thead><tbody><tr><th headers="hd_h_ch10.tab3_1_1_1_1 hd_h_ch10.tab3_1_1_1_2" id="hd_b_ch10.tab3_1_1_1_1" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Hospital-based staff</th></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospital-based scientific and professional staff<sup>(b)</sup></td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£24-£77 per working hour (Band 2 – Band 8b)</td></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospital-based nurses</td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£86-£130 per hour of patient contact (Band 5 – 7)</td></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospital-based doctors</td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£29-£106 (FY1 – Consultant)</td></tr><tr><th headers="hd_h_ch10.tab3_1_1_1_1 hd_h_ch10.tab3_1_1_1_2" id="hd_b_ch10.tab3_1_1_5_1" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Community-based staff</th></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">General practitioner</td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£199 per hour of patient contact</td></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Community-based scientific and professional Staff<sup>(b)</sup></td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£23-£74 per working hour (Band 2 – Band 8b)</td></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Community nurse</td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£22-£73 per working hour (Band 2 – Band 8b)</td></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nurse (GP practice)</td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£36 per working hour</td></tr><tr><td headers="hd_h_ch10.tab3_1_1_1_1 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Social Worker (adult services)</td><td headers="hd_h_ch10.tab3_1_1_1_2 hd_b_ch10.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£55 per hour of client-related work</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>(a)</dt><dd><div id="ch10.tab3_1"><p class="no_margin">Source: Curtis (2016)<a class="bibr" href="#ch10.ref1" rid="ch10.ref1"><sup>1</sup></a></p></div></dd></dl><dl class="bkr_refwrap"><dt>(b)</dt><dd><div id="ch10.tab3_2"><p class="no_margin">Please see Curtis (2016)<a class="bibr" href="#ch10.ref1" rid="ch10.ref1"><sup>1</sup></a> for details of the health care professionals included in this category by band. Examples include: Physiotherapists, Occupational therapists, Counsellors, Pharmacists.</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch10appatab1"><div id="ch10.appa.tab1" class="table"><h3><span class="label">Table 4</span><span class="title">Review protocol for what is the best method/service to review service provision and identify when additional services may be required in people thought to be entering their last year of life?</span></h3><div class="caption"><p>Question number: Q5</p><p>Relevant section of Scope:</p><p>Service delivery models for end of life care, including both acute, community and third sector settings covering:
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<ul id="ch10.l10"><li id="ch10.lt41" class="half_rhythm"><div>types of services (supportive and palliative care) provided by generalists and specialists during the course of the last year of life,</div></li><li id="ch10.lt42" class="half_rhythm"><div>who delivers the services and how, multidisciplinary team composition,</div></li><li id="ch10.lt43" class="half_rhythm"><div>timing and review of service provision,</div></li><li id="ch10.lt44" class="half_rhythm"><div>location of services, for example, place of care,</div></li><li id="ch10.lt45" class="half_rhythm"><div>out of hours, weekend and 24/7 availability of services.</div></li></ul></p></div><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appa.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appa.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">ID</th><th id="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Field</th><th id="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Content</th></tr></thead><tbody><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">I</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review question</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">What is the best method/service to review service provision and identify when additional services may be required in people thought to be entering their last year of life?</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">II</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Type of review question</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Intervention</p>
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<p>A review of health economic evidence related to the same review question was conducted in parallel with this review. For details see the health economic review protocol for this NICE guideline.</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">III</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Objective of the review</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">To identify the best method/service to review service provision and identify when additional services may be required in people thought to be entering their last year of life</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">IV</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – population / disease / condition / issue / domain</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adults (aged over 18 or over) with progressive life-limiting conditions thought to be entering the last year of life.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">V</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – intervention(s) / exposure(s) / prognostic factor(s)</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l11"><li id="ch10.lt46" class="half_rhythm"><div>Method/service to review service provision and identify when additional services may be required in people thought to be entering their last year of life</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VI</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – comparator(s) / control or reference (gold) standard</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l12"><li id="ch10.lt47" class="half_rhythm"><div>Combinations of methods/services to review service provision and identify when additional services may be required in people thought to be entering their last year of life</div></li><li id="ch10.lt48" class="half_rhythm"><div>To each other</div></li><li id="ch10.lt49" class="half_rhythm"><div>No standardized method/service to review service provision and identify when additional services may be required</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes and prioritisation</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CRITICAL
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<ul id="ch10.l13"><li id="ch10.lt50" class="half_rhythm"><div>Quality of life (Continuous)</div></li><li id="ch10.lt51" class="half_rhythm"><div>Preferred and actual place of death (Dichotomous)</div></li><li id="ch10.lt52" class="half_rhythm"><div>Preferred and actual place of care (Dichotomous)</div></li></ul>
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IMPORTANT
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<ul id="ch10.l14"><li id="ch10.lt53" class="half_rhythm"><div>Length of survival (Dichotomous)</div></li><li id="ch10.lt54" class="half_rhythm"><div>Length of stay (Continuous)</div></li><li id="ch10.lt55" class="half_rhythm"><div>Hospitalisation (Dichotomous)</div></li><li id="ch10.lt56" class="half_rhythm"><div>Number of hospital visits (Dichotomous)</div></li><li id="ch10.lt57" class="half_rhythm"><div>Number of visits to accident and emergency (Dichotomous)</div></li><li id="ch10.lt58" class="half_rhythm"><div>Number of unscheduled admissions (Dichotomous)</div></li><li id="ch10.lt59" class="half_rhythm"><div>Use of community services (Dichotomous)</div></li><li id="ch10.lt60" class="half_rhythm"><div>Avoidable/inappropriate admissions to ICU (Dichotomous)</div></li><li id="ch10.lt61" class="half_rhythm"><div>Inappropriate attempt at cardiopulmonary resuscitation (Dichotomous)</div><div>Staff satisfaction (Continuous)</div></li><li id="ch10.lt62" class="half_rhythm"><div>Patient/carer reported outcomes (satisfaction) (Continuous)</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VIII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – study design</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l15"><li id="ch10.lt63" class="half_rhythm"><div>Systematic reviews</div></li><li id="ch10.lt64" class="half_rhythm"><div>RCTs</div></li><li id="ch10.lt65" class="half_rhythm"><div>Non-randomised comparative studies, including before and after studies.</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">IX</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Other inclusion exclusion criteria</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions:
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<ul id="ch10.l16"><li id="ch10.lt66" class="half_rhythm"><div>Children (17 years or younger)</div></li><li id="ch10.lt67" class="half_rhythm"><div>Studies will only be included if they reported one or more of the outcomes listed above</div></li><li id="ch10.lt68" class="half_rhythm"><div>Descriptive (non-comparative) studies will be excluded</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">X</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Proposed sensitivity / subgroup analysis, or meta-regression</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Subgroups to be analysed if heterogeneity found:
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<ul id="ch10.l17"><li id="ch10.lt69" class="half_rhythm"><div>Younger adults (aged 18-25)</div></li><li id="ch10.lt70" class="half_rhythm"><div>Frail elderly</div></li><li id="ch10.lt71" class="half_rhythm"><div>People with dementia</div></li><li id="ch10.lt72" class="half_rhythm"><div>People with hearing loss</div></li><li id="ch10.lt73" class="half_rhythm"><div>People with advanced heart and lung disease</div></li><li id="ch10.lt74" class="half_rhythm"><div>People in prisons</div></li><li id="ch10.lt75" class="half_rhythm"><div>Socioeconomic inequalities (people from lower income brackets)</div></li><li id="ch10.lt76" class="half_rhythm"><div>Homeless people/vulnerably housed</div></li><li id="ch10.lt77" class="half_rhythm"><div>Travelers</div></li><li id="ch10.lt78" class="half_rhythm"><div>People with learning difficulties</div></li><li id="ch10.lt79" class="half_rhythm"><div>People with disabilities</div></li><li id="ch10.lt80" class="half_rhythm"><div>People with mental health problems</div></li><li id="ch10.lt81" class="half_rhythm"><div>Migrant workers</div></li><li id="ch10.lt82" class="half_rhythm"><div>LGBT</div></li><li id="ch10.lt83" class="half_rhythm"><div>People in whom life-prolonging therapies are still an active option</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XI</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Selection process – duplicate screening / selection / analysis</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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|
<ul id="ch10.l18"><li id="ch10.lt84" class="half_rhythm"><div>Due to the expected complexity of the service models implemented in the studies, studies will be reported separately if necessary. In such case, studies on the populations included in the subgroup list will be highlighted to the Committee and will be considered when making the recommendations</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data management (software)</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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|
<ul id="ch10.l19"><li id="ch10.lt85" class="half_rhythm"><div>Pairwise meta-analyses were performed using Cochrane Review Manager (RevMan5).</div></li><li id="ch10.lt86" class="half_rhythm"><div>GRADEpro was used to assess the quality of evidence for each outcome.</div></li><li id="ch10.lt87" class="half_rhythm"><div>EndNote was used for bibliography, citations, sifting and reference management</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Information sources – databases and dates</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Clinical search databases to be used: Medline, Embase, Cochrane Library, Current Nursing and Allied Health Literature (CINAHL), PsycINFO, Healthcare Management Information Consortium (HMIC), Social Policy and Practice (SSP), Applied Social Sciences Index and Abstracts (ASSIA)</p>
|
|
<p>Date: All years</p>
|
|
<p>Health economics search databases to be used: Medline, Embase, NHSEED, HTA</p>
|
|
<p>Date: Medline, Embase from 2014</p>
|
|
<p>NHSEED, HTA – All years</p>
|
|
<p>Language: Restrict to English only</p>
|
|
<p>A call for evidence was also conducted.</p>
|
|
</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIV</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Identify if an update</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not applicable</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XV</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Author contacts</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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|
<a href="https://www.nice.org.uk/guidance/indevelopment/gid-cgwave0799" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.nice.org<wbr style="display:inline-block"></wbr>​.uk/guidance/indevelopment<wbr style="display:inline-block"></wbr>​/gid-cgwave0799</a>
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|
</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVI</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Highlight if amendment to previous protocol</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see section 4.5 of <a href="https://www.nice.org.uk/article/pmg20/chapter/4-Developing-review-questions-and-planning-the-evidence-review#planning-the-evidence-review" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search strategy – for one database</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see <a href="#ch10.appb">appendix B</a></td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVIII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data collection process – forms / duplicate</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A standardised evidence table format will be used, and published as <a href="#ch10.appd">appendix D</a> of the evidence report.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIX</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data items – define all variables to be collected</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see evidence tables in <a href="#ch10.appd">Appendix D</a> (clinical evidence tables) or <a href="#ch10.appg">G</a> (health economic evidence tables).</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XX</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Methods for assessing bias at outcome / study level</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Standard study checklists were used to critically appraise individual studies. For details please see section 6.2 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a></p>
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<p>The risk of bias across all available evidence was evaluated for each outcome using an adaptation of the ‘Grading of Recommendations Assessment, Development and Evaluation (GRADE) toolbox’ developed by the international GRADE working group <a href="http://www.gradeworkinggroup.org/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.gradeworkinggroup.org/</a></p>
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<p>[Please document any deviations/alternative approach when GRADE isn’t used or if a modified GRADE approach has been used for non-intervention or non-comparative studies.]</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXI</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Criteria for quantitative synthesis</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see section 6.4 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Methods for quantitative analysis – combining studies and exploring (in)consistency</p>
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</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see the separate <a href="/books/NBK558772/bin/bm1.pdf">Methods</a> report for this guideline.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meta-bias assessment – publication bias, selective reporting bias</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>For details please see section 6.2 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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<p>[Consider exploring publication bias for review questions where it may be more common, such as pharmacological questions and certain disease areas. Describe any steps taken to mitigate against publication bias, such as examining trial registries.]</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIV</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Confidence in cumulative evidence</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see sections 6.4 and 9.1 of <a href="https://www.nice.org.uk/article/pmg20/chapter/1-Introduction-and-overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXV</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rationale / context – what is known</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see the introduction to the evidence review.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVI</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Describe contributions of authors and guarantor</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>A multidisciplinary committee</p>
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<p>[<a href="https://www.nice.org.uk/guidance/indevelopment/gid-cgwave0799" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.nice.org<wbr style="display:inline-block"></wbr>​.uk/guidance/indevelopment<wbr style="display:inline-block"></wbr>​/gid-cgwave0799</a>] developed the evidence review. The committee was convened by the National Guideline Centre (NGC) and chaired by Mark Thomas in line with section 3 of <a href="https://www.nice.org.uk/article/pmg20/chapter/1%20Introduction%20and%20overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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<p>Staff from NGC undertook systematic literature searches, appraised the evidence, conducted meta-analysis and cost-effectiveness analysis where appropriate, and drafted the evidence review in collaboration with the committee. For details please see <a href="https://www.nice.org.uk/article/pmg20/chapter/1-Introduction-and-overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sources of funding / support</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NGC is funded by NICE and hosted by the Royal College of Physicians.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVIII</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Name of sponsor</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NGC is funded by NICE and hosted by the Royal College of Physicians.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIX</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Roles of sponsor</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NICE funds NGC to develop guidelines for those working in the NHS, public health and social care in England.</td></tr><tr><td headers="hd_h_ch10.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXX</td><td headers="hd_h_ch10.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PROSPERO registration number</td><td headers="hd_h_ch10.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not registered</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appatab2"><div id="ch10.appa.tab2" class="table"><h3><span class="label">Table 5</span><span class="title">Review protocol for when and how frequently should service need provision be reviewed in people thought to be in their last year of life?</span></h3><div class="caption"><p>Question number: Q7</p><p>Relevant section of Scope:</p><p>Service delivery models for end of life care, including both acute, community and third sector settings covering:
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<ul id="ch10.l20"><li id="ch10.lt88" class="half_rhythm"><div>types of services (supportive and palliative care) provided by generalists and specialists during the course of the last year of life,</div></li><li id="ch10.lt89" class="half_rhythm"><div>who delivers the services and how, multidisciplinary team composition,</div></li><li id="ch10.lt90" class="half_rhythm"><div>timing and review of service provision,</div></li><li id="ch10.lt91" class="half_rhythm"><div>location of services, for example, place of care,</div></li><li id="ch10.lt92" class="half_rhythm"><div>out of hours, weekend and 24/7 availability of services.</div></li></ul>
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</p><p>Field names are based on <a href="http://www.prisma-statement.org/Extensions/Protocols.aspx" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">PRISMA-P</a>.]</p></div><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appa.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appa.tab2_lrgtbl__"><table><thead><tr><th id="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">ID</th><th id="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Field</th><th id="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Content</th></tr></thead><tbody><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">I</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review question</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">When and how frequently should service need provision be reviewed in people thought to be in their last year of life?:</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">II</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Type of review question</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Intervention</p>
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<p>A review of health economic evidence related to the same review question was conducted in parallel with this review. For details see the health economic review protocol for this NICE guideline.</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">III</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Objective of the review</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">To identify the best timing or frequency to review service provision in people thought to be entering their last year of life</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">IV</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – population / disease / condition / issue / domain</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adults (aged over 18 or over) with progressive life-limiting conditions thought to be entering the last year of life.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">V</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – intervention(s) / exposure(s) / prognostic factor(s)</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l21"><li id="ch10.lt93" class="half_rhythm"><div>Timing/frequency to review service provision in people thought to be entering their last year of life</div></li></ul>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VI</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Eligibility criteria – comparator(s) / control or reference (gold) standard</p>
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</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l22"><li id="ch10.lt94" class="half_rhythm"><div>To each other</div></li><li id="ch10.lt95" class="half_rhythm"><div>No standardized timing/frequency to review service provision</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes and prioritisation</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CRITICAL
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<ul id="ch10.l23"><li id="ch10.lt96" class="half_rhythm"><div>Quality of life (Continuous)</div></li><li id="ch10.lt97" class="half_rhythm"><div>Preferred and actual place of death (Dichotomous)</div></li><li id="ch10.lt98" class="half_rhythm"><div>Preferred and actual place of care (Dichotomous)</div></li><li id="ch10.lt99" class="half_rhythm"><div>Length of survival (Dichotomous)</div></li></ul>
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IMPORTANT
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<ul id="ch10.l24"><li id="ch10.lt100" class="half_rhythm"><div>Length of stay (Continuous)</div></li><li id="ch10.lt101" class="half_rhythm"><div>Hospitalisation (Dichotomous)</div></li><li id="ch10.lt102" class="half_rhythm"><div>Number of hospital visits (Dichotomous)</div></li><li id="ch10.lt103" class="half_rhythm"><div>Number of visits to accident and emergency (Dichotomous)</div></li><li id="ch10.lt104" class="half_rhythm"><div>Number of unscheduled admissions (Dichotomous)</div></li><li id="ch10.lt105" class="half_rhythm"><div>Use of community services (Dichotomous)</div></li><li id="ch10.lt106" class="half_rhythm"><div>Avoidable/inappropriate admissions to ICU (Dichotomous)</div></li><li id="ch10.lt107" class="half_rhythm"><div>Inappropriate attempt at cardiopulmonary resuscitation (Dichotomous)</div><div>Staff satisfaction (Continuous)</div></li><li id="ch10.lt108" class="half_rhythm"><div>Patient/carer reported outcomes (satisfaction) (Continuous)</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VIII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – study design</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l25"><li id="ch10.lt109" class="half_rhythm"><div>Systematic reviews</div></li><li id="ch10.lt110" class="half_rhythm"><div>RCTs</div></li><li id="ch10.lt111" class="half_rhythm"><div>Non-randomised comparative studies, including before and after studies.</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">IX</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Other inclusion exclusion criteria</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions:
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<ul id="ch10.l26"><li id="ch10.lt112" class="half_rhythm"><div>Children (17 years or younger)</div></li><li id="ch10.lt113" class="half_rhythm"><div>Studies will only be included if they reported one or more of the outcomes listed above</div></li><li id="ch10.lt114" class="half_rhythm"><div>Descriptive (non-comparative) studies will be excluded</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">X</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Proposed sensitivity / subgroup analysis, or meta-regression</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Subgroups to be analysed if heterogeneity found:
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<ul id="ch10.l27"><li id="ch10.lt115" class="half_rhythm"><div>Younger adults (aged 18-25)</div></li><li id="ch10.lt116" class="half_rhythm"><div>Frail elderly</div></li><li id="ch10.lt117" class="half_rhythm"><div>People with dementia</div></li><li id="ch10.lt118" class="half_rhythm"><div>People with hearing loss</div></li><li id="ch10.lt119" class="half_rhythm"><div>People with advanced heart and lung disease</div></li><li id="ch10.lt120" class="half_rhythm"><div>People in prisons</div></li><li id="ch10.lt121" class="half_rhythm"><div>Socioeconomic inequalities (people from lower income brackets)</div></li><li id="ch10.lt122" class="half_rhythm"><div>Homeless people/vulnerably housed</div></li><li id="ch10.lt123" class="half_rhythm"><div>Travellers</div></li><li id="ch10.lt124" class="half_rhythm"><div>People with learning difficulties</div></li><li id="ch10.lt125" class="half_rhythm"><div>People with disabilities</div></li><li id="ch10.lt126" class="half_rhythm"><div>People with mental health problems</div></li><li id="ch10.lt127" class="half_rhythm"><div>Migrant workers</div></li><li id="ch10.lt128" class="half_rhythm"><div>LGBT</div></li><li id="ch10.lt129" class="half_rhythm"><div>People in whom life-prolonging therapies are still an active option</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XI</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Selection process – duplicate screening / selection / analysis</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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|
<ul id="ch10.l28"><li id="ch10.lt130" class="half_rhythm"><div>Due to the expected complexity of the service models implemented in the studies, studies will be reported separately if necessary. In such case, studies on the populations included in the subgroup list will be highlighted to the Committee and will be considered when making the recommendations</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data management (software)</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<ul id="ch10.l29"><li id="ch10.lt131" class="half_rhythm"><div>Pairwise meta-analyses were performed using Cochrane Review Manager (RevMan5).</div></li><li id="ch10.lt132" class="half_rhythm"><div>GRADEpro was used to assess the quality of evidence for each outcome.</div></li><li id="ch10.lt133" class="half_rhythm"><div>EndNote was used for citations and bibliographies</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Information sources – databases and dates</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Databases: Medline, Embase, The Cochrane LIbrary</p>
|
|
<p>Date limits for search: all years</p>
|
|
<p>Language: English only</p>
|
|
<p>A call for evidence was also conducted.</p>
|
|
</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIV</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Identify if an update</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not applicable</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XV</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Author contacts</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a href="https://www.nice.org.uk/guidance/indevelopment/gid-cgwave0799" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.nice.org<wbr style="display:inline-block"></wbr>​.uk/guidance/indevelopment<wbr style="display:inline-block"></wbr>​/gid-cgwave0799</a>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVI</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Highlight if amendment to previous protocol</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see section 4.5 of <a href="https://www.nice.org.uk/article/pmg20/chapter/4-Developing-review-questions-and-planning-the-evidence-review#planning-the-evidence-review" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search strategy – for one database</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see <a href="#ch10.appb">appendix B</a></td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVIII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data collection process – forms / duplicate</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A standardised evidence table format will be used, and published as <a href="#ch10.appd">appendix D</a> of the evidence report.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIX</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data items – define all variables to be collected</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see evidence tables in <a href="#ch10.appd">Appendix D</a> (clinical evidence tables) or <a href="#ch10.appg">G</a> (health economic evidence tables).</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XX</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Methods for assessing bias at outcome / study level</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Standard study checklists were used to critically appraise individual studies. For details please see section 6.2 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a></p>
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<p>The risk of bias across all available evidence was evaluated for each outcome using an adaptation of the ‘Grading of Recommendations Assessment, Development and Evaluation (GRADE) toolbox’ developed by the international GRADE working group <a href="http://www.gradeworkinggroup.org/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.gradeworkinggroup.org/</a></p>
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<p>[Please document any deviations/alternative approach when GRADE isn’t used or if a modified GRADE approach has been used for non-intervention or non-comparative studies.]</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXI</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Criteria for quantitative synthesis</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see section 6.4 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Methods for quantitative analysis – combining studies and exploring (in)consistency</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see the separate <a href="/books/NBK558772/bin/bm1.pdf">Methods</a> report for this guideline.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meta-bias assessment – publication bias, selective reporting bias</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>For details please see section 6.2 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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<p>[Consider exploring publication bias for review questions where it may be more common, such as pharmacological questions and certain disease areas. Describe any steps taken to mitigate against publication bias, such as examining trial registries.]</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIV</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Confidence in cumulative evidence</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see sections 6.4 and 9.1 of <a href="https://www.nice.org.uk/article/pmg20/chapter/1-Introduction-and-overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXV</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rationale / context – what is known</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see the introduction to the evidence review.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVI</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Describe contributions of authors and guarantor</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>A multidisciplinary committee</p>
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<p>[<a href="https://www.nice.org.uk/guidance/indevelopment/gid-cgwave0799" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.nice.org<wbr style="display:inline-block"></wbr>​.uk/guidance/indevelopment<wbr style="display:inline-block"></wbr>​/gid-cgwave0799</a>] developed the evidence review. The committee was convened by the National Guideline Centre (NGC) and chaired by Mark Thomas in line with section 3 of <a href="https://www.nice.org.uk/article/pmg20/chapter/1%20Introduction%20and%20overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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<p>Staff from NGC undertook systematic literature searches, appraised the evidence, conducted meta-analysis and cost-effectiveness analysis where appropriate, and drafted the evidence review in collaboration with the committee. For details please see <a href="https://www.nice.org.uk/article/pmg20/chapter/1-Introduction-and-overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sources of funding / support</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NGC is funded by NICE and hosted by the Royal College of Physicians.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVIII</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Name of sponsor</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NGC is funded by NICE and hosted by the Royal College of Physicians.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIX</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Roles of sponsor</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NICE funds NGC to develop guidelines for those working in the NHS, public health and social care in England.</td></tr><tr><td headers="hd_h_ch10.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXX</td><td headers="hd_h_ch10.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PROSPERO registration number</td><td headers="hd_h_ch10.appa.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not registered</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appatab3"><div id="ch10.appa.tab3" class="table"><h3><span class="label">Table 6</span><span class="title">Health economic review protocol</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appa.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appa.tab3_lrgtbl__"><table><thead><tr><th id="hd_h_ch10.appa.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Review question</th><th id="hd_h_ch10.appa.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">All questions – health economic evidence</th></tr></thead><tbody><tr><td headers="hd_h_ch10.appa.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>Objectives</b>
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</td><td headers="hd_h_ch10.appa.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">To identify health economic studies relevant to any of the review questions.</td></tr><tr><td headers="hd_h_ch10.appa.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>Search criteria</b>
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</td><td headers="hd_h_ch10.appa.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch10.l30"><li id="ch10.lt134" class="half_rhythm"><div>Populations, interventions and comparators must be as specified in the clinical review protocol above.</div></li><li id="ch10.lt135" class="half_rhythm"><div>Studies must be of a relevant health economic study design (cost–utility analysis, cost-effectiveness analysis, cost–benefit analysis, cost–consequences analysis, comparative cost analysis).</div></li><li id="ch10.lt136" class="half_rhythm"><div>Studies must not be a letter, editorial or commentary, or a review of health economic evaluations. (Recent reviews will be ordered although not reviewed. The bibliographies will be checked for relevant studies, which will then be ordered.)</div></li><li id="ch10.lt137" class="half_rhythm"><div>Unpublished reports will not be considered unless submitted as part of a call for evidence.</div></li><li id="ch10.lt138" class="half_rhythm"><div>Studies must be in English.</div></li></ul></td></tr><tr><td headers="hd_h_ch10.appa.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>Search strategy</b>
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</td><td headers="hd_h_ch10.appa.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A health economic study search will be undertaken using population-specific terms and a health economic study filter – see <a href="#ch10.appa">appendix A</a>.</td></tr><tr><td headers="hd_h_ch10.appa.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>Review strategy</b>
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</td><td headers="hd_h_ch10.appa.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Studies not meeting any of the search criteria above will be excluded. Studies published before 2007, abstract-only studies and studies from non-OECD countries or the USA will also be excluded.</p>
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<p>Each remaining study will be assessed for applicability and methodological limitations using the NICE economic evaluation checklist which can be found in <a href="#ch10.apph">appendix H</a> of Developing NICE guidelines: the manual (2014).<a class="bibr" href="#ch10.ref7" rid="ch10.ref7"><sup>7</sup></a></p>
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<p><b>Inclusion and exclusion criteria</b>
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<ul id="ch10.l31"><li id="ch10.lt139" class="half_rhythm"><div>If a study is rated as both ‘Directly applicable’ and with ‘Minor limitations’ then it will be included in the guideline. A health economic evidence table will be completed and it will be included in the health economic evidence profile.</div></li><li id="ch10.lt140" class="half_rhythm"><div>If a study is rated as either ‘Not applicable’ or with ‘Very serious limitations’ then it will usually be excluded from the guideline. If it is excluded then a health economic evidence table will not be completed and it will not be included in the health economic evidence profile.</div></li><li id="ch10.lt141" class="half_rhythm"><div>If a study is rated as ‘Partially applicable’, with ‘Potentially serious limitations’ or both then there is discretion over whether it should be included.</div></li></ul>
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<b>Where there is discretion</b></p>
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<p>The health economist will make a decision based on the relative applicability and quality of the available evidence for that question, in discussion with the guideline committee if required. The ultimate aim is to include health economic studies that are helpful for decision-making in the context of the guideline and the current NHS setting. If several studies are considered of sufficiently high applicability and methodological quality that they could all be included, then the health economist, in discussion with the committee if required, may decide to include only the most applicable studies and to selectively exclude the remaining studies. All studies excluded on the basis of applicability or methodological limitations will be listed with explanation as excluded health economic studies in appendix M.</p>
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<p>The health economist will be guided by the following hierarchies.</p>
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<p><i>Setting:</i>
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<ul id="ch10.l32"><li id="ch10.lt142" class="half_rhythm"><div>UK NHS (most applicable).</div></li><li id="ch10.lt143" class="half_rhythm"><div>OECD countries with predominantly public health insurance systems (for example, France, Germany, Sweden).</div></li><li id="ch10.lt144" class="half_rhythm"><div>OECD countries with predominantly private health insurance systems (for example, Switzerland).</div></li><li id="ch10.lt145" class="half_rhythm"><div>Studies set in non-OECD countries or in the USA will be excluded before being assessed for applicability and methodological limitations.</div></li></ul>
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<i>Health economic study type:</i>
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<ul id="ch10.l33"><li id="ch10.lt146" class="half_rhythm"><div>Cost–utility analysis (most applicable).</div></li><li id="ch10.lt147" class="half_rhythm"><div>Other type of full economic evaluation (cost–benefit analysis, cost-effectiveness analysis, cost–consequences analysis).</div></li><li id="ch10.lt148" class="half_rhythm"><div>Comparative cost analysis.</div></li><li id="ch10.lt149" class="half_rhythm"><div>Non-comparative cost analyses including cost-of-illness studies will be excluded before being assessed for applicability and methodological limitations.</div></li></ul>
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<i>Year of analysis:</i>
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<ul id="ch10.l34"><li id="ch10.lt150" class="half_rhythm"><div>The more recent the study, the more applicable it will be.</div></li><li id="ch10.lt151" class="half_rhythm"><div>Studies published in 2007 or later but that depend on unit costs and resource data entirely or predominantly from before 2007 will be rated as ‘Not applicable’.</div></li><li id="ch10.lt152" class="half_rhythm"><div>Studies published before 2007 will be excluded before being assessed for applicability and methodological limitations.</div></li></ul>
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<i>Quality and relevance of effectiveness data used in the health economic analysis:</i>
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<ul id="ch10.l35"><li id="ch10.lt153" class="half_rhythm"><div>The more closely the clinical effectiveness data used in the health economic analysis match with the outcomes of the studies included in the clinical review the more useful the analysis will be for decision-making in the guideline.</div></li></ul></p>
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</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab1"><div id="ch10.appb.tab1" class="table"><h3><span class="label">Table 7</span><span class="title">Database date parameters and filters used</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Database</th><th id="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dates searched</th><th id="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search filter used</th></tr></thead><tbody><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Medline (Ovid)</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1946 – 04 January 2019</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions</td></tr><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Embase (Ovid)</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1974 – 04 January 2019</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions</td></tr><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The Cochrane Library (Wiley)</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Cochrane Reviews to Issue 1 of 12, January 2019</p>
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<p>CENTRAL to Issue 1 of 12, January 2019</p>
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<p>DARE, and NHSEED to Issue 2 of 4 2015</p>
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<p>HTA to Issue 4 of 4 2016</p>
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</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CINAHL, Current Nursing and Allied Health Literature (EBSCO)</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inception – 04 January 2019</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Limiters - English Language; Exclude MEDLINE records; Publication Type: Clinical Trial, Journal Article, Meta Analysis, Randomized Controlled Trial, Systematic Review: Age Groups: All Adult; Language: English</td></tr><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PsycINFO (ProQuest)</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inception – 04 January 2019</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study type</td></tr><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">HMIC. Healthcare Management Information Consortium (Ovid)</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1979 – 04 January 2019</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions</td></tr><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">SPP, Social Policy and Practice</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1981 – 04 January 2019</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study types</td></tr><tr><td headers="hd_h_ch10.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">ASSIA, Applied Social Sciences Index and Abstracts (ProQuest)</td><td headers="hd_h_ch10.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1987 – 04 January 2019</td><td headers="hd_h_ch10.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab2"><div id="ch10.appb.tab2" class="table"><h3><span class="title">Medline (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab2_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Palliative care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminally Ill/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nursing Homes/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospices/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Advance Care Planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Continuity of Patient Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Physician-Patient Relations/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long-Term Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Delivery of Health Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-29</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">news/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp historical article/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anecdotes as Topic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">comment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/31-38</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39 not 40</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animals/ not humans/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animals, Laboratory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experimentation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Models, Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodentia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/41-47</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30 not 48</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 49 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50 not 51</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(service* adj3 (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52 and 53</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(commission* adj2 (support* or service* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((service* or program* or co-ordinat* or co ordinat* or coordinat*) adj2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Critical Pathways/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((critical or clinic* or service* or care) adj2 path*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Patient Care Bundles/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(care adj2 (bundle* or service* or package* or standard*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/55-60</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(assess* or criteria* or predict* or recogni* or identif* or refer*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52 and 61 and 62</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">gold standard*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52 and 64</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(amber adj2 bundle).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63 or 65 or 66</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">patient care team/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">interdisciplinary communication/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((integrat* or network*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(key adj2 work*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj2 (lead or leader or leads or facilitat*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj1 profession*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Case Management/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(case adj2 manage*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(co-ordinator* or coordinator* or coordinate* or co-ordinate*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/68-77</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Social Welfare/ec, ed, es, eh, ma, st, sn, td [Economics, Education, Ethics, Ethnology, Manpower, Standards, Statistics & Numerical Data, Trends]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Charities/ec, ed, es, ma, mt, og, st, sn, sd, td, ut [Economics, Education, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Home Care Services/ec, ed, es, ma, mt, og, st, sn, sd, td, ut [Economics, Education, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Community Health Nursing/ec, ed, es, ma, mt, og, st, sn, sd, td, ut [Economics, Education, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Telemedicine/ec, es, ma, mt, og, st, sn, td, ut [Economics, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp remote consultation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*telemedicine/ or *telepathology/ or *teleradiology/ or *telerehabilitation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telemedicine or tele medicine or telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or telepathology or teleradiology or telerehabilitatio).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((tele* or remote) adj2 consult*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mobile Health Units/ec, es, ma, og, st, sn, sd, td, ut [Economics, Ethics, Manpower, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(mobile adj2 (health or care) adj2 unit*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital-based home care or HBHC or hospital-based hospice care or acute hospital care).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital adj3 (domicil* or home)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home hospitali*ation.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Home Care Agencies/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(social adj (welfare or care)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* adj4 (home-visit* or home visit* or home-based or home based)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) adj nurs*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(community adj2 (health care or healthcare or nursing or nurse*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali*ation* or admission* or readmission* or admit*) adj3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/78-98</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Continuity of Patient Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Aftercare/ or *Patient discharge/ or *Patient handoff/ or *Patient transfer/ or *Transitional care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Patient Discharge Summaries/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((patient* or person* or people or nursing* or clinic*) adj (discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or caring or serv*) adj2 (continu* or change* or transition* or transfer*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(discharg* adj2 (facilitat* or rapid* or pathway* or path way* or plan* or program*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/100-105</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">109.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/107-108</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">110.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Caregiver/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">111.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Spouse/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">112.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Family/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">113.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">114.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/110-113</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">115.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((replacement or break* or holiday* or respite) adj3 (care* or service*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">116.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((communit* or support* or psychosocial* or psycholog*) adj3 (service* or group* or system*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">117.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((group* or support* or psychosocial* or psycholog*) adj3 (selfhelp or self help or therap*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">118.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((psychosocial* or psycholog*) adj2 support*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">119.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Self-Help/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">120.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Social support/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">121.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Counseling/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">122.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(counseling or counselling*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">123.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(buddy* or buddies).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">124.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((health* or medical*) adj2 check*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">125.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*) adj3 (education or educate or educating or information or literature or leaflet* or booklet* or pamphlet* or website* or knowledge)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">126.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/115-125</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">127.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52 and 114 and 126</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">128.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52 and (78 or 99 or 106 or 109)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">129.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54 or 67 or 127 or 128</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab3"><div id="ch10.appb.tab3" class="table"><h3><span class="title">Embase (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab3_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Palliative therapy/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminally ill patient/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Nursing home/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Doctor patient relation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long term care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Health care delivery/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-28</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter.pt. or letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">note.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/ or case study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/30-34</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35 not 36</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal/ not human/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">nonhuman/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experiment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Experimental Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodent/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/37-44</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29 not 45</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 46 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 not 48</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(service* adj3 (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 50</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(commission* adj2 (support* or service* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((service* or program* or co-ordinat* or co ordinat* or coordinat*) adj2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Clinical Pathway/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((critical or clinic* or service* or care) adj2 path*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Care Bundle/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(care adj2 (bundle* or service* or package* or standard*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/52-57</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(assess* or criteria* or predict* or recogni* or identif* or refer*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 58 and 59</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">gold standard*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 61</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(amber adj2 bundle).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60 or 62 or 63</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">interdisciplinary communication/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">patient care team*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((integrat* or network*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(key adj2 work*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj2 (lead or leader or leads or facilitat*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj1 profession*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Case Management/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(case adj2 manage*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(co-ordinator* or coordinator* or coordinate* or co-ordinate*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/65-74</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*social welfare/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*community health nursing/ or *community care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*senior center/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*telemedicine/ or *telehealth/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*teleconsultation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or mobile health unit*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*home care/ or *home health agency/ or *home monitoring/ or *home oxygen therapy/ or *home physiotherapy/ or *home rehabilitation/ or *home respiratory care/ or *respite care/ or *visiting nursing service/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*health care personnel/ or *health auxiliary/ or *nursing home personnel/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telemedicine or tele medicine or telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or telepathology or teleradiology or telerehabilitatio).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((tele* or remote) adj2 consult*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(mobile adj2 (health or care) adj2 unit*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital-based home care or HBHC or hospital-based hospice care or acute hospital care).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital adj3 (domicil* or home)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home hospitali*ation.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(social adj (welfare or care)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* adj4 (home-visit* or home visit* or home-based or home based)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) adj nurs*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(community adj2 (health care or healthcare or nursing or nurse*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali*ation* or admission* or readmission* or admit*) adj3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/76-94</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*patient care/ or *case management/ or *patient care planning/ or *rapid response team/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*aftercare/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*hospital discharge/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*clinical handover/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*transitional care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*medical record/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((patient* or person* or people or nursing* or clinic*) adj (discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or caring or serv*) adj2 (continu* or change* or transition* or transfer*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(discharg* adj2 (facilitat* or rapid* or pathway* or path way* or plan* or program*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/96-105</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">109.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/107-108</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">110.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Caregiver/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">111.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Spouse/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">112.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Family/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">113.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">114.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/110-113</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">115.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((replacement or break* or holiday* or respite) adj3 (care* or service*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">116.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((communit* or support* or psychosocial* or psycholog*) adj3 (service* or group* or system*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">117.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((group* or support* or psychosocial* or psycholog*) adj3 (selfhelp or self help or therap*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">118.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((psychosocial* or psycholog*) adj2 support*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">119.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Self-Help/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">120.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Social support/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">121.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Counseling/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">122.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(counseling or counselling*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">123.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(buddy* or buddies).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">124.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((health* or medical*) adj2 check*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">125.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*) adj3 (education or educate or educating or information or literature or leaflet* or booklet* or pamphlet* or website* or knowledge)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">126.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/115-125</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">127.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 114 and 126</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">128.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and (75 or 95 or 106 or 109)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">129.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51 or 64 or 127 or 128</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab4"><div id="ch10.appb.tab4" class="table"><h3><span class="title">Cochrane Library (Wiley) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab4_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Palliative Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Terminal Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Hospice Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Terminally Ill] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) near/2 (care* or caring or ill*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) near (phase* or stage*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Nursing Homes] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(care or nursing) near/2 (home or homes):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Respite Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) near/2 (care or caring)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Hospices] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Care Planning] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Continuity of Patient Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) near/3 (care or caring) near/3 (continu* or plan*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Attitude to Death] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* near/3 (death* or dying*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Physician-Patient Relations] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Long-Term Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Delivery of Health Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end near/2 life):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) near/2 (year or month*) near/2 life):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) near/2 (patient* or person* or people or care or caring)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Advance Care Planning] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* near/2 (plan* or decision* or directive*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #1-#28)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">service* near/3 (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29 and #30</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(commission* near/2 (support* or service* or model*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((service* or program* or co-ordinat* or co ordinat* or coordinat*) near/2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Critical Pathways] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((critical or clinic* or service* or care) near/2 path*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Care Bundles] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(care near/2 (bundle* or service* or package* or standard*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #34-#37)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(assess* or criteria* or predict* or recogni* or identif* or refer*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29 and #38 and #39</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">gold standard*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29 and #41</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(amber near/2 bundle):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#40 or #43 or #43</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Care Team] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Interdisciplinary Communication] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) near/2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((integrat* or network*) near/2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(key near/2 work*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) near/2 (lead or leader or leads or facilitat*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) near/1 profession*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Case Management] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(case near/2 manage*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(co-ordinator* or coordinator* or coordinate* or co-ordinate*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #45-#54)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Social Welfare] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Charities] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Adult Day Care Centers] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Community Health Nursing] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Care Services] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Senior Centers] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Telemedicine] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Remote Consultation] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Mobile Health Units] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((community based or community dwelling home or rural) near/3 (care or health care or healthcare)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital-based home care or HBHC or hospital-based hospice care or acute hospital care):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali*ation* or admission* or readmission* or admit*) near/3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(home based versus hospital based):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital near/3 (domicil* or home)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(home hospitali*ation):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Care Services, Hospital-Based] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Health Nursing] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Homemaker Services] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Care Agencies] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Health Aides] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(social care):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Nurses, Community Health] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* near/4 (home-visit* or home visit* or home-based or home based)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) near nurs*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(Or #56-#80)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Continuity of Patient Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Aftercare] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Discharge] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Handoff] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Transfer] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Transitional Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Discharge Summaries] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((patient* or person* or people or nursing* or clinic*) near (discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or caring or serv*) near/2 (continu* or change* or transition* or transfer*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(discharg* near/2 (facilitat* or rapid* or pathway* or path way* or plan* or program*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #82-#90)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Advance Care Planning] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* near/2 (plan* or decision* or directive*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #93-#95)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Caregivers] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Spouses] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Family] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #97-#100)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((replacement or break* or holiday* or respite) near/3 (care* or service*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((communit* or support* or psychosocial* or psycholog*) near/3 (service* or group* or system*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((group* or support* or psychosocial* or psycholog*) near/3 (selfhelp or self help or therap*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((psychosocial* or psycholog*) near/2 support*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Self-Help Groups] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Social Support] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Counseling] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#109.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(counseling or counselling*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#110.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(buddy* or buddies):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#111.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health or medical*) near/3 check*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#112.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*) near/3 (education or educate or educating or information or literature or leaflet* or booklet* or pamphlet* or website* or knowledge):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#113.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #102-#112)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#114.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29 and 101 and 113</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#115.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29 and (#55 or #81 or #92 or #96)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#116.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#31 or #44 or #114 or #115</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab5"><div id="ch10.appb.tab5" class="table"><h3><span class="title">CINAHL (EBSCO) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab5/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab5_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Palliative care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Terminal care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Hospice care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI palliat* OR AB palliat*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MW Terminally ill</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (terminal* or long term or longterm) AND TI (care* or caring or ill*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (terminal* or long term or longterm) AND AB (care* or caring or ill*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (dying or terminal) AND TI (phase* or stage*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (dying or terminal) AND AB (phase* or stage*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI life limit* OR AB life limit*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Nursing homes</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (care or nursing) AND TI (home or homes)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (care or nursing) AND AB (home or homes)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Respite care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (respite or day) AND TI (care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (respite or day) AND AB (care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Hospices</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI Hospice* OR AB Hospice*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Patient Care Plans”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Continuity of Patient Care”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (advance* or patient*) AND TI (care or caring) AND TI (continu* or plan*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (advance* or patient*) AND AB (care or caring) AND AB (continu* or plan*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Attitude to Death</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI attitude* AND TI (death* or dying)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB attitude* AND AB (death* or dying)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Physician-Patient Relations</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Long Term Care”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Health Care Delivery”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI end AND TI life OR AB end AND AB life</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI EOLC OR AB EOLC</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (last or final) AND TI (year or month) AND TI life</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (last or final) AND AB (year or month) AND AB life</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (dying or death) AND TI (patient* or person* or people or care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (dying or death) AND AB (patient* or person* or people or care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Advance Care Planning”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TX service* AND TX (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB service* AND AB (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S37 OR S38</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI commission* AND TI ((support* or service* or model*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB commission* AND AB ((support* or service* or model*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (service* or program* or co-ordinat* or co ordinat* or coordinat*) AND TI (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (service* or program* or co-ordinat* or co ordinat* or coordinat*) AND AB (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (critical or clinic* or service* or care) AND TI path*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (critical or clinic* or service* or care) AND AB path*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI care AND TI (bundle* or service* or package* or standard*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB care AND AB (bundle* or service* or package* or standard*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S40 OR S41 OR S42 OR S43 OR S44 OR S45 OR S46 OR S47</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (assess* or criteria* or predict* or recogni* or identif* or refer*) OR AB (assess* or criteria* or predict* or recogni* or identif* or refer*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S36 AND S48 AND S49</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI gold standard* OR AB gold standard*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S36 AND S51</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI amber AND TI bundle</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB amber AND AB bundle</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S53 OR S54</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S48 OR S50 OR S55</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Multidisciplinary Care Team+”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MDT OR IDT</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) n2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((integrat* or network*) n2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (key n2 work*) OR AB (key n2 work*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (((healthcare or care) n2 (lead or leader or leads or facilitat*))) OR AB (((healthcare or care) n2 (lead or leader or leads or facilitat*)))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (((healthcare or care) n1 profession*)) OR AB (((healthcare or care) n1 profession*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Case Management</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (case n2 manage*) OR AB (case n2 manage*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI ((co-ordinator* or coordinator* or coordinate* or co-ordinate*)*)) OR AB ((co-ordinator* or coordinator* or coordinate* or co-ordinate*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S57 OR S58 OR S59 OR S60 OR S61 OR S62 OR S63 OR S64 OR S65 OR S66</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Social Welfare”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Charities”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Adult Day Center (Saba CCC)”) OR (MM “Housing for the Elderly”) OR (MM “Older Adult Care (Saba CCC)”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Community Health Nursing+”) OR (MM “Community Health Centers”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Home Health Care+”) OR (MM “Home Health Aides”) OR (MM “Home Health Care Information Systems”) OR (MM “Home Health Aide Service (Saba CCC)”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Housing for the Elderly”) OR (MM “Rural Health Centers”) OR (MM “Community Health Centers”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Telemedicine+”) OR (MH “Telehealth+”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Remote Consultation”) OR (MM “Telephone Consultation (Iowa NIC)”) OR (MM “Services for Australian Rural and Remote Allied Health”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or senior center*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Rural Health Personnel”) OR (MM “Mobile Health Units”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">remote consultation</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((community based or community dwelling home or rural) n3 (care or health care or healthcare))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospital-based home care or HBHC or hospital-based hospice care or acute hospital care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali?ation* or admission* or readmission* or admit*) n3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home based versus hospital based</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital n3 (domicil* or home))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home hospitali?ation</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home care service*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Home Health Agencies”) OR (MM “Nursing Home Personnel”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Homemaker Services”) OR (MM “Health Services for the Aged”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Home Health Care+”) OR (MM “Home Care Equipment and Supplies”) OR (MH “Nursing Homes”) OR (MM “National Association for Home Care & Hospice”) OR (MM “Nursing Home Patients”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">social care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Hospitals, Community”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Home Nursing”) OR (MM “Home Nursing, Professional”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* n4 (home-visit* or home visit* or home-based or home based))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) n nurs*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S68 OR S69 OR S70 OR S71 OR S72 OR S73 OR S74 OR S75 OR S76 OR S77 OR S78 OR S79 OR S80 OR S81 OR S82 OR S83 OR S84 OR S85 OR S86 OR S87 OR S88 OR S89 OR S90 OR S91 OR S92 OR S93</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Continuity of Patient Care OR MH Aftercare OR MH Patient discharge OR MH Patient handoff OR MH Patient transfer OR MH Transitional care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Discharge Planning”) OR (MM “Patient Discharge Summaries”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (((patient* or person* or people or nursing* or clinic*)) AND TX ((discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (((patient* or person* or people or nursing* or clinic*)) AND AB ((discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB ((care or caring or serv*)) AND AB ((continu* or change* or transition* or transfer*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI ((care or caring or serv*)) AND TI ((continu* or change* or transition* or transfer*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI discharg* AND TI (facilitat* or rapid* or pathway* or path way* or plan* or program*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB discharg* AND AB (facilitat* or rapid* or pathway* or path way* or plan* or program*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S95 OR S96 OR S97 OR S98 OR S99 OR S100 OR S101 OR S102</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI advance* AND TI (plan* or decision* or directive*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB advance* AND AB (plan* or decision* or directive*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S104 OR S105</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S36 AND (S67 OR S94 OR S103 OR S106)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S39 OR S56 OR S107</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab6"><div id="ch10.appb.tab6" class="table"><h3><span class="title">PsycINFO (ProQuest) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab6/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab6_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(ti,ab(commission* NEAR/2 (support* OR service* OR model*)) OR ((service* OR program* OR co-ordinat* OR coordinat*) NEAR/2 (model* OR deliver* OR strateg* OR support* OR access* OR method* OR system* OR policies OR policy OR availab*))) AND (SU.EXACT(“Palliative Care”) OR SU.EXACT(“Terminally Ill Patients”) OR SU.EXACT(“Hospice”) OR ti,ab(palliat*) OR ti,ab((terminal* OR long-term OR longterm) NEAR/2 (care* OR caring OR ill*)) OR ti,ab((dying OR terminal) NEAR/1 (phase* OR stage*)) OR ti,ab(life-limit*) OR SU.EXACT(“Nursing Homes”) OR ti,ab((care OR nursing) NEAR/2 (home OR homes)) OR SU.EXACT(“Respite Care”) OR ti,ab((respite OR day) NEAR/2 (care OR caring)) OR ti,ab(hospice*) OR MJSUB.EXACT(“Treatment Planning”) OR MJSUB.EXACT(“Continuum of Care”) OR ti,ab((advance* OR patient*) NEAR/3 (care OR caring) NEAR/3 (continu* OR plan*)) OR MJSUB.EXACT(“Long Term Care”) OR ti,ab(attitude* NEAR/3 (death* OR dying*)) OR ti,ab(end NEAR/2 life) OR ti,ab(EOLC) OR ti,ab((last OR final) NEAR/2 (year OR month*) NEAR/2 life) OR ti,ab((dying OR death) NEAR/2 (patient* OR person* OR people OR care OR caring)))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adolescence (13-17 Yrs), Adulthood (18 Yrs & Older), Aged (65 Yrs & Older), Middle Age (40-64 Yrs), Thirties (30-39 Yrs), Very Old (85 Yrs & Older), Young Adulthood (18-29 Yrs)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1 and 2</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference Proceedings, Journal Article, Peer Reviewed Journal</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3 and 4</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab7"><div id="ch10.appb.tab7" class="table"><h3><span class="title">HMIC (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab7/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab7_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp End of life care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(terminal* adj ill*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/2-8</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp Paediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp older people/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9 not 10</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 11 to English</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 12 to (audiovis or book or chapter dh helmis or circular or microfiche dh helmis or multimedias or website)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 12 to (audiocass or books or cdrom or chapter or dept pubs or diskettes or folio pamp or “map” or marc or microfiche or multimedia or pamphlet or parly or press or press rel or thesis or trustdoc or video or videos or website)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13 or 14</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12 not 15</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">euthanasia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">euthanasia.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17 or 18</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16 not 19</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab8"><div id="ch10.appb.tab8" class="table"><h3><span class="title">SPP (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab8/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab8_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nursing adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(terminal* adj2 ill*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(respite adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-15</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(child* or infant*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(adult* or adolescent*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17 not 18</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16 not 19</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 20 to (journal or journal article or online resource or online report or report)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab9"><div id="ch10.appb.tab9" class="table"><h3><span class="title">ASSIA (ProQuest) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab9/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab9_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab. ((ti,ab(commission* N/2 (support* or service* or model*)) OR ti,ab((service* or program* or co-ordinat* or coordinat*) N/2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*))) AND ((SU.EXACT(“Care” OR “Clinical nursing” OR “Community homes” OR “Community nursery nursing” OR “Community nursing” OR “Compassionate care” OR “Continuing care” OR “District nursing” OR “Family centred care” OR “Geriatric wards” OR “Group care” OR “Health visiting” OR “Home care” OR “Home from home care” OR “Home health aides” OR “Home helps” OR “Hospices” OR “Hostel wards” OR “Informal care” OR “Integrated care pathways” OR “Intentional care” OR “Intermediate care” OR “Intermediate care centres” OR “Lack of care” OR “Learning disability nursing” OR “Length of stay” OR “Liaison nursing” OR “Long stay wards” OR “Long term care” OR “Long term home care” OR “Long term residential care” OR “Nurse led care” OR “Nursing” OR “Occupational health nursing” OR “Ontological care” OR “Out of home care” OR “Outreach nursing” OR “Palliative care” OR “Paranursing” OR “Pastoral care” OR “Patient care” OR “Primary nursing” OR “Private residential care” OR “Process centred care” OR “Quality of care” OR “Radical health visiting” OR “Residential care” OR “Residential group care” OR “Respite care” OR “Shared care” OR “Social care” “Temporary care” OR “Terminal care” OR “Wards”) OR (SU.EXACT(“Terminally ill elderly people”) OR SU.EXACT(“Terminally ill fathers”) OR SU.EXACT(“Terminally ill elderly men”) OR SU.EXACT(“Terminally ill elderly women”) OR SU.EXACT(“Terminally ill young adults”) OR SU.EXACT(“Terminally ill parents”) OR SU.EXACT(“Terminally ill women”) OR SU.EXACT(“Terminally ill widowed sisters”) OR SU.EXACT(“Terminally ill colleagues”) OR SU.EXACT(“Terminally ill young girls”) OR SU.EXACT(“Terminally ill people”) OR SU.EXACT(“Terminally ill men”)) OR SU.EXACT(“Advance directives” OR “Do not resuscitate orders” OR “Durable power of attorney for health care” OR “Living wills” OR “Treatment preferences” OR “Treatment needs”)) OR (ti,ab((advance* or patient*) N/3 (care or caring) N/3 (continu* or plan*)) or ti,ab(attitude* N/3 (death* or dying*)) or ti,ab(end N/2 life) or ti,ab(EOLC) or ti,ab((last or final) N/2 (year or month*) N/2 life) or ti,ab((dying or death) N/2 (patient* or person* or people or care or caring))))) OR SU.EXACT(“End of life decisions”)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab10"><div id="ch10.appb.tab10" class="table"><h3><span class="label">Table 8</span><span class="title">Database date parameters and filters used</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab10/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab10_lrgtbl__"><table><thead><tr><th id="hd_h_ch10.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Database</th><th id="hd_h_ch10.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dates searched</th><th id="hd_h_ch10.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search filter used</th></tr></thead><tbody><tr><td headers="hd_h_ch10.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Medline</td><td headers="hd_h_ch10.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2014 – 04 January 2019</td><td headers="hd_h_ch10.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Exclusions</p>
|
|
<p>Health economics studies</p>
|
|
<p>Health economics modelling studies</p>
|
|
<p>Quality of life studies</p>
|
|
</td></tr><tr><td headers="hd_h_ch10.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Embase</td><td headers="hd_h_ch10.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2014 – 204 January 2019</td><td headers="hd_h_ch10.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Exclusions</p>
|
|
<p>Health economics studies</p>
|
|
<p>Health economics modelling studies</p>
|
|
<p>Quality of life studies</p>
|
|
</td></tr><tr><td headers="hd_h_ch10.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Centre for Research and Dissemination (CRD)</td><td headers="hd_h_ch10.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>HTA - Inception – 04 January 2019</p>
|
|
<p>NHSEED - Inception to March 2015</p>
|
|
</td><td headers="hd_h_ch10.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab11"><div id="ch10.appb.tab11" class="table"><h3><span class="title">Medline (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab11/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab11_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Palliative care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminally Ill/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nursing Homes/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospices/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Advance Care Planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Continuity of Patient Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Physician-Patient Relations/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long-Term Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Delivery of Health Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-29</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">news/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp historical article/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anecdotes as Topic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">comment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/31-38</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39 not 40</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animals/ not humans/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animals, Laboratory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experimentation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Models, Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodentia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/41-47</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30 not 48</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 49 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50 not 51</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">economics/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">value of life/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp “costs and cost analysis”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Economics, Hospital/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Economics, medical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Economics, nursing/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">economics, pharmaceutical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp “Fees and Charges”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp budgets/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cost*.ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(economic* or pharmaco?economic*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(price* or pricing*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cost* adj2 (effectiv* or utilit* or benefit* or minimi* or unit* or estimat* or variable*)).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(financ* or fee or fees).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(value adj2 (money or monetary)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/53-68</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp models, economic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Models, Theoretical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Models, Organizational/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">markov chains/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">monte carlo method/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Decision Theory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(markov* or monte carlo).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">econom* model*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(decision* adj2 (tree* or analy* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/70-78</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">quality-adjusted life years/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(quality adj2 (wellbeing or well being)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">disability adjusted life.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qal* or qtime* or qwb* or daly*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(euroqol* or eq5d* or eq 5*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qol* or hql* or hqol* or h qol* or hrqol* or hr qol*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health utility* or utility score* or disutilit* or utility value*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hui or hui1 or hui2 or hui3).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health* year* equivalent* or hye or hyes).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">discrete choice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rosser.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(willingness to pay or time tradeoff or time trade off or tto or standard gamble*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf36* or sf 36* or short form 36* or shortform 36* or shortform36*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf20 or sf 20 or short form 20 or shortform 20 or shortform20).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf12* or sf 12* or short form 12* or shortform 12* or shortform12*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf8* or sf 8* or short form 8* or shortform 8* or shortform8*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf6* or sf 6* or short form 6* or shortform 6* or shortform6*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/80-98</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52 and (69 or 79 or 99)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab12"><div id="ch10.appb.tab12" class="table"><h3><span class="title">Embase (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab12/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab12_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Palliative therapy/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminally ill patient/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Nursing home/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Doctor patient relation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long term care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Health care delivery/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-28</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter.pt. or letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">note.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/ or case study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/30-34</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35 not 36</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal/ not human/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">nonhuman/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experiment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Experimental Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodent/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/37-44</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29 not 45</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 46 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 not 48</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">health economics/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp economic evaluation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp health care cost/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp fee/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">funding/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cost*.ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(economic* or pharmaco?economic*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(price* or pricing*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cost* adj2 (effectiv* or utilit* or benefit* or minimi* or unit* or estimat* or variable*)).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(financ* or fee or fees).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(value adj2 (money or monetary)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/50-62</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">statistical model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp economic aspect/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64 and 65</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*theoretical model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*nonbiological model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">stochastic model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">decision theory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">decision tree/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">monte carlo method/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(markov* or monte carlo).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">econom* model*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(decision* adj2 (tree* or analy* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/66-75</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">quality-adjusted life years/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">“quality of life index”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">short form 12/ or short form 20/ or short form 36/ or short form 8/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(quality adj2 (wellbeing or well being)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">disability adjusted life.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qal* or qtime* or qwb* or daly*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(euroqol* or eq5d* or eq 5*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qol* or hql* or hqol* or h qol* or hrqol* or hr qol*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health utility* or utility score* or disutilit* or utility value*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hui or hui1 or hui2 or hui3).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health* year* equivalent* or hye or hyes).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">discrete choice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rosser.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(willingness to pay or time tradeoff or time trade off or tto or standard gamble*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf36* or sf 36* or short form 36* or shortform 36* or shortform36*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf20 or sf 20 or short form 20 or shortform 20 or shortform20).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf12* or sf 12* or short form 12* or shortform 12* or shortform12*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf8* or sf 8* or short form 8* or shortform 8* or shortform8*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf6* or sf 6* or short form 6* or shortform 6* or shortform6*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/77-97</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and (63 or 76 or 98)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appbtab13"><div id="ch10.appb.tab13" class="table"><h3><span class="title">NHS EED and HTA (CRD) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appb.tab13/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appb.tab13_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Palliative Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Terminal Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Hospice Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(palliat*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Terminally Ill IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((terminal* or long term or longterm) adj2 (care* or caring or ill*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((dying or terminal) adj (phase* or stage*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(life limit*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Nursing Homes IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((care or nursing) adj2 (home or homes))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Respite Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((respite or day) adj2 (care or caring))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Hospices IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospice*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Advance Care Planning EXPLODE ALL TREES IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* adj2 (plan* or decision* or directive*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(living will*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Patient Care Planning IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Continuity of Patient Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Attitude to Death IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((attitude* adj3 (death* or dying*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Physician-Patient Relations IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Long-Term Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Delivery of Health Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((end adj2 life)) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(EOLC) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((last or final) adj2 (year or month*) adj2 life)) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((dying or death) adj2 (patient* or person* or people or care or caring))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 OR #27 OR #28 OR #29</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(#30) IN NHSEED</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(#30) IN HTA</td></tr></tbody></table></div></div></article><article data-type="fig" id="figobch10appcfig1"><div id="ch10.appc.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%201.%20Flow%20chart%20of%20clinical%20study%20selection%20for%20the%20review%20of%20review%20of%20service%20provision.&p=BOOKS&id=558772_ch10appcf1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558772/bin/ch10appcf1.jpg" alt="Figure 1. Flow chart of clinical study selection for the review of review of service provision." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 1</span><span class="title">Flow chart of clinical study selection for the review of review of service provision</span></h3></div></article><article data-type="fig" id="figobch10appgfig1"><div id="ch10.appg.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%202.%20Flow%20chart%20of%20health%20economic%20study%20selection%20for%20the%20guideline.&p=BOOKS&id=558772_ch10appgf1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558772/bin/ch10appgf1.jpg" alt="Figure 2. Flow chart of health economic study selection for the guideline." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 2</span><span class="title">Flow chart of health economic study selection for the guideline</span></h3><div class="caption"><p>* Non-relevant population, intervention, comparison, design or setting; non-English language</p></div></div></article><article data-type="table-wrap" id="figobch10apphtab1"><div id="ch10.apph.tab1" class="table"><h3><span class="label">Table 9</span><span class="title">Studies excluded from the clinical review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.apph.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.apph.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusion reason</th></tr></thead><tbody><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Edwards 2013<a class="bibr" href="#ch10.ref2" rid="ch10.ref2"><sup>2</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hu 2014<a class="bibr" href="#ch10.ref3" rid="ch10.ref3"><sup>3</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Jacob 2010<a class="bibr" href="#ch10.ref4" rid="ch10.ref4"><sup>4</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Inappropriate study design</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lam 2017<a class="bibr" href="#ch10.ref5" rid="ch10.ref5"><sup>5</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Miller 2017<a class="bibr" href="#ch10.ref6" rid="ch10.ref6"><sup>6</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Schenker 2017<a class="bibr" href="#ch10.ref8" rid="ch10.ref8"><sup>8</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">White 2002<a class="bibr" href="#ch10.ref9" rid="ch10.ref9"><sup>9</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wilson 2017<a class="bibr" href="#ch10.ref10" rid="ch10.ref10"><sup>10</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td></tr><tr><td headers="hd_h_ch10.apph.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Yilmaz 2005<a class="bibr" href="#ch10.ref11" rid="ch10.ref11"><sup>11</sup></a></td><td headers="hd_h_ch10.apph.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Inappropriate study design</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch10appitab1"><div id="ch10.appi.tab1" class="table"><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558772/table/ch10.appi.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch10.appi.tab1_lrgtbl__"><table><tbody><tr><th id="hd_b_ch10.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PICO question</th><td headers="hd_b_ch10.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>What are the benefits of planned regular reviews versus as required review of non-cancer patients in last year of life?</b>
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</p>
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<p>Population: People entering the last year of life with a chronic progressive disease such as COPD, renal failure or dementia. For example in COPD after first respiratory crisis requiring non-invasive ventilation; or in CRF after first course of haemodialysis; or soon after diagnosis with dementia whilst person still has capacity to consent.</p>
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<p>Intervention(s): A standardised holistic needs assessment tool validated for non-cancer patients, after identification of entering last year of life and repeated at pre-determined points in the disease process. The HNA should be followed by a consultation with a disease-specific specialist and/or a specialist palliative care professional. The frequency of HNAs should be set at appropriate rates for different disease groups and reflecting prognostic information, for example, they may need to become more frequent as disease progresses.</p>
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<p>Comparison: Same populations but not offered HNA or referral to disease-specific specialist and/or SPC at first identification of entering last year of life, being followed up at usual care intervals by usual healthcare professionals.</p>
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<p>Outcome(s): Benefits of planned regular assessments in terms of (a) identification of health, social care and other needs which require additional specific interventions by current professionals/practitioners or by referral to new staff; (b) improvement in symptom management, functioning and quality of life; (c) avoidance of crises; (d) reduction in unplanned hospital visits and admissions; (e) survival; (f) carer experience.</p>
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<p>The research could help to identify triggers in disease processes when holistic needs assessment and SPC input are most effective.</p>
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</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Importance to patients or the population</th><td headers="hd_b_ch10.appi.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Patients with cancer are already recommended to have holistic needs assessments from diagnosis and at key points in their illness. They are also referred, to varying extents, to SPC teams in hospitals or community during the last year of life. This research would bring new evidence to the larger group of people who in the last year of life, who have non-cancer conditions and often multimorbidity. Because of the potentially large numbers and impact on the NHS, it is important to know how often such patients should be assessed and reviewed by SPC services.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Relevance to NICE guidance</th><td headers="hd_b_ch10.appi.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Relevant to future updates of NICE End of Life Care Service Delivery guideline, and NICE guidelines for specific chronic diseases, which have been lacking on evidence for this question.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Relevance to the NHS</th><td headers="hd_b_ch10.appi.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Optimisation of NHS-funded community-based services for non-cancer conditions; optimal use of current resources and allocation of future resources; identification of potential future extended role for hospice community-based services; improving education and training of community staff, effective use of resources and enable more effective individual case management.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">National priorities</th><td headers="hd_b_ch10.appi.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The research could help to deliver the priorities of the NHS programme for improving end of life care for people with all conditions. It could also support existing and future national service frameworks for specific diseases.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_6_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Current evidence base</th><td headers="hd_b_ch10.appi.tab1_1_1_6_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Many of the studies carried out in this area have been conducted in other countries where the healthcare systems are very different from the UK. There was also little evidence found for holistic needs assessment and review of non-cancer patients as opposed to those with cancer.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Equality</th><td headers="hd_b_ch10.appi.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">There is inequality in access to some services for end of life care between people with a cancer diagnosis and those with a non-cancer diagnosis which may result in similar disease progression and symptoms, for example comparing lung cancer and chronic respiratory disease. Many people in the last year of life have physical disabilities and cognitive impairments which restrict their ability to attend hospitals for secondary care review. This research may help people with non-cancer conditions access to DS1500 or other benefits.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_8_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study design</th><td headers="hd_b_ch10.appi.tab1_1_1_8_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This should be a primary research study with a prospective design, comparing people with have a HNA followed up by specialist level review, and further assessments and reviews, to a matched population who have usual care. The design could be a RCT or carefully controlled case-matched parallel cohort study. Randomisation could be at cluster (for example, GP practice) or individual patient level. Both quantitative and qualitative methodologies could be used, using a nested approach. An in-built feasibility study with clear criteria for progression to a larger RCT or cohort study should be included.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Feasibility</th><td headers="hd_b_ch10.appi.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The intervention may carry significant NHS research support costs because of the need for additional assessments and specialist reviews. However the study may point to future NHS savings if unplanned secondary level care is avoided. Ethical constraints include the need to obtain and maintain consent from patients who may have deteriorating mental capacity.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_10_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Other comments</th><td headers="hd_b_ch10.appi.tab1_1_1_10_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">As well as NIHR, disease-specific charities such as British Heart Foundation, British Lung Foundation, Motor Neurone Disease Association may be interested to fund a study in their populations.</td></tr><tr><th id="hd_b_ch10.appi.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Importance</th><td headers="hd_b_ch10.appi.tab1_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">High: the research is essential to inform future updates of key recommendations in the guideline.</td></tr></tbody></table></div></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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