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class="bkr_bib"><h1 id="_NBK558771_"><span itemprop="name">Evidence review: Out of hours services</span></h1><div class="subtitle">End of life care for adults: service delivery</div><p><b>Evidence review K</b></p><p><i>NICE Guideline, No. 142</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">National Guideline Centre (UK)</span>.</p><div class="half_rhythm">London: <a href="https://www.nice.org.uk" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">National Institute for Health and Care Excellence (NICE)</span></a>; <span itemprop="datePublished">2019 Oct</span>.<div class="small">ISBN-13: <span itemprop="isbn">978-1-4731-3560-4</span></div></div><div><a href="/books/about/copyright/">Copyright</a> © NICE 2019.</div></div><div class="bkr_clear"></div></div><div id="ch11.s1"><h2 id="_ch11_s1_">1. Out of hours services</h2><div id="ch11.s1.1"><h3>1.1. Review question: What are the best out of hours services, models and policies to support people in their last year of life to stay in their preferred place of care?</h3><p>It is important that adults who are likely to be in the last year of life, and those important to them, should have access to professional care and to necessary medications at all times of day and night, and throughout the week. Many services operating outside acute settings, such as primary care and community palliative care teams, work ‘office hours’, that is, between 8am and 5pm; and with limited or no availability on weekends. Even in hospitals and other in-patient settings such as care homes and hospices, levels of specialist staff are commonly limited out of hours.<a class="bibr" href="#ch11.ref140" rid="ch11.ref140"><sup>140</sup></a> The committee regarded these gaps in service as important because lack of access to trained staff’ or to special medicines’ out of hours may mean that people have to be transferred – often against their prior wishes - to a different setting such as hospital emergency departments. For this reason, different types of services aimed at people likely to be in the last year of life have been developed, including outreach from hospices, community-based teams, and telephone advice services. The committee was aware that there is marked variation across the country in the implementation of these solutions, and their costs vary significantly depending on the staffing levels and extended hours of work.</p><p>The committee wanted to review the evidence for different models of out of hours services and policies, which would enable more people to remain in the care setting of their choice and avoid unnecessary transfers.</p></div><div id="ch11.s1.2"><h3>1.2. PICO table</h3><p>For full details see the review protocol in <a href="#ch11.appa">Appendix A</a>.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab1"><a href="/books/NBK558771/table/ch11.tab1/?report=objectonly" target="object" title="Table 1" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab1" rid-ob="figobch11tab1"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab1/?report=thumb" src-large="/books/NBK558771/table/ch11.tab1/?report=previmg" alt="Table 1. PICO characteristics of review question." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab1"><a href="/books/NBK558771/table/ch11.tab1/?report=objectonly" target="object" rid-ob="figobch11tab1">Table 1</a></h4><p class="float-caption no_bottom_margin">PICO characteristics of review question. </p></div></div></div><div id="ch11.s1.3"><h3>1.3. Clinical evidence</h3><p>A search was conducted for studies comparing out of hours services, models and policies to support people with progressive life-limiting conditions thought to be entering their last year of life to stay in their preferred place of care.</p><p>Four studies (reported in 5 papers) were included in the review<a class="bibr" href="#ch11.ref57" rid="ch11.ref57"><sup>57</sup></a><sup>,</sup>
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<a class="bibr" href="#ch11.ref77" rid="ch11.ref77"><sup>77</sup></a><sup>,</sup>
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<a class="bibr" href="#ch11.ref133" rid="ch11.ref133"><sup>133</sup></a><sup>,</sup>
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<a class="bibr" href="#ch11.ref137" rid="ch11.ref137"><sup>137</sup></a><sup>,</sup>
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<a class="bibr" href="#ch11.ref146" rid="ch11.ref146"><sup>146</sup></a>; these are summarised in <a class="figpopup" href="/books/NBK558771/table/ch11.tab2/?report=objectonly" target="object" rid-figpopup="figch11tab2" rid-ob="figobch11tab2">Table 2</a> below. Services delivered out of hours which were a component of a more complex intervention have been included; all interventions details are reported below and in <a href="#ch11.appe">Appendix E</a>. Some studies evaluated the availability of a service rather than the access to a service; where relevant, this has been reported in <a class="figpopup" href="/books/NBK558771/table/ch11.tab3/?report=objectonly" target="object" rid-figpopup="figch11tab3" rid-ob="figobch11tab3">Table 3</a>.</p><p>Evidence from these studies is summarised in the clinical evidence summary below (<a class="figpopup" href="/books/NBK558771/table/ch11.tab4/?report=objectonly" target="object" rid-figpopup="figch11tab4" rid-ob="figobch11tab4">Table 4</a>). See also the study selection flow chart in <a href="#ch11.appc">Appendix C</a>, forest plots in <a href="#ch11.appe">Appendix E</a>, study evidence tables in <a href="#ch11.appd">Appendix D</a> and GRADE tables in <a href="#ch11.appf">Appendix F</a>.</p><div id="ch11.s1.3.1"><h4>1.3.1. Excluded studies</h4><p>See the excluded studies list in <a href="#ch11.appi">Appendix I</a>.</p></div><div id="ch11.s1.3.2"><h4>1.3.2. </h4><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab2"><a href="/books/NBK558771/table/ch11.tab2/?report=objectonly" target="object" title="Table 2" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab2" rid-ob="figobch11tab2"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab2/?report=thumb" src-large="/books/NBK558771/table/ch11.tab2/?report=previmg" alt="Table 2. Summary of clinical studies included in the evidence review." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab2"><a href="/books/NBK558771/table/ch11.tab2/?report=objectonly" target="object" rid-ob="figobch11tab2">Table 2</a></h4><p class="float-caption no_bottom_margin">Summary of clinical studies included in the evidence review. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab3"><a href="/books/NBK558771/table/ch11.tab3/?report=objectonly" target="object" title="Table 3" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab3" rid-ob="figobch11tab3"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab3/?report=thumb" src-large="/books/NBK558771/table/ch11.tab3/?report=previmg" alt="Table 3. Proportion of participants using out of hours services." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab3"><a href="/books/NBK558771/table/ch11.tab3/?report=objectonly" target="object" rid-ob="figobch11tab3">Table 3</a></h4><p class="float-caption no_bottom_margin">Proportion of participants using out of hours services. </p></div></div><p>See <a href="#ch11.appd">Appendix D</a> for full evidence tables.</p></div><div id="ch11.s1.3.3"><h4>1.3.3. Quality assessment of clinical studies included in the evidence review</h4><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab4"><a href="/books/NBK558771/table/ch11.tab4/?report=objectonly" target="object" title="Table 4" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab4" rid-ob="figobch11tab4"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab4/?report=thumb" src-large="/books/NBK558771/table/ch11.tab4/?report=previmg" alt="Table 4. Clinical evidence summary: out of hours service (Rapid response service available) versus usual care (Rapid response service not available) in adults with progressive life-limiting conditions thought to be entering their last year of life." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab4"><a href="/books/NBK558771/table/ch11.tab4/?report=objectonly" target="object" rid-ob="figobch11tab4">Table 4</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: out of hours service (Rapid response service available) versus usual care (Rapid response service not available) in adults with progressive life-limiting conditions thought to be entering their last year of life. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab5"><a href="/books/NBK558771/table/ch11.tab5/?report=objectonly" target="object" title="Table 5" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab5" rid-ob="figobch11tab5"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab5/?report=thumb" src-large="/books/NBK558771/table/ch11.tab5/?report=previmg" alt="Table 5. Clinical evidence summary: out of hours service (Rapid response service users) versus usual care (Rapid response service non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab5"><a href="/books/NBK558771/table/ch11.tab5/?report=objectonly" target="object" rid-ob="figobch11tab5">Table 5</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: out of hours service (Rapid response service users) versus usual care (Rapid response service non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab6"><a href="/books/NBK558771/table/ch11.tab6/?report=objectonly" target="object" title="Table 6" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab6" rid-ob="figobch11tab6"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab6/?report=thumb" src-large="/books/NBK558771/table/ch11.tab6/?report=previmg" alt="Table 6. Clinical evidence summary: out of hours service (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme with out of hours non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab6"><a href="/books/NBK558771/table/ch11.tab6/?report=objectonly" target="object" rid-ob="figobch11tab6">Table 6</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: out of hours service (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme with out of hours non-users) in adults with progressive life-limiting conditions thought to be entering <a href="/books/NBK558771/table/ch11.tab6/?report=objectonly" target="object" rid-ob="figobch11tab6">(more...)</a></p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab7"><a href="/books/NBK558771/table/ch11.tab7/?report=objectonly" target="object" title="Table 7" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab7" rid-ob="figobch11tab7"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab7/?report=thumb" src-large="/books/NBK558771/table/ch11.tab7/?report=previmg" alt="Table 7. Clinical evidence summary: out of hours service (Delivering Choice Programme with out of hours users) versus other service (Delivering Choice Programme without out of hours users) in adults with progressive life-limiting conditions thought to be entering their last year of life." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab7"><a href="/books/NBK558771/table/ch11.tab7/?report=objectonly" target="object" rid-ob="figobch11tab7">Table 7</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: out of hours service (Delivering Choice Programme with out of hours users) versus other service (Delivering Choice Programme without out of hours users) in adults with progressive life-limiting conditions thought to be entering <a href="/books/NBK558771/table/ch11.tab7/?report=objectonly" target="object" rid-ob="figobch11tab7">(more...)</a></p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab8"><a href="/books/NBK558771/table/ch11.tab8/?report=objectonly" target="object" title="Table 8" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab8" rid-ob="figobch11tab8"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab8/?report=thumb" src-large="/books/NBK558771/table/ch11.tab8/?report=previmg" alt="Table 8. Clinical evidence summary: out of hours service (Palliative home care service) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab8"><a href="/books/NBK558771/table/ch11.tab8/?report=objectonly" target="object" rid-ob="figobch11tab8">Table 8</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: out of hours service (Palliative home care service) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life. </p></div></div><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab9"><a href="/books/NBK558771/table/ch11.tab9/?report=objectonly" target="object" title="Table 9" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab9" rid-ob="figobch11tab9"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab9/?report=thumb" src-large="/books/NBK558771/table/ch11.tab9/?report=previmg" alt="Table 9. Clinical evidence summary: out of hours service (Specialist palliative care team) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab9"><a href="/books/NBK558771/table/ch11.tab9/?report=objectonly" target="object" rid-ob="figobch11tab9">Table 9</a></h4><p class="float-caption no_bottom_margin">Clinical evidence summary: out of hours service (Specialist palliative care team) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life. </p></div></div><p>See <a href="#ch11.appf">Appendix F</a> for full GRADE tables.</p></div></div><div id="ch11.s1.4"><h3>1.4. Economic evidence</h3><div id="ch11.s1.4.1"><h4>1.4.1. Included studies</h4><p>No relevant health economic studies were included.</p></div><div id="ch11.s1.4.2"><h4>1.4.2. Excluded studies</h4><p>One economic study relating to this review question was identified but was excluded due to a combination of limited applicability and methodological limitations.<a class="bibr" href="#ch11.ref57" rid="ch11.ref57"><sup>57</sup></a> This is listed in <a href="#ch11.appi">Appendix I</a>, with reasons for exclusion given.</p><p>See also the health economic study selection flow chart in <a href="#ch11.appg">Appendix G</a>.</p></div><div id="ch11.s1.4.3"><h4>1.4.3. Health economic costing analysis</h4><p>End-of-life community services and out-of-hours end-of-life services were the areas of the guideline that were prioritised by the guideline committee for original economic analysis. A costing analysis, with a threshold analysis, was conducted to estimate imprecisely the cost of a number of community services, available out-of-hours and investigate how plausible it is that they could break even. These should not be taken to be a prescription for such services which will vary considerably in order to meet local needs.</p><p>The services were assumed to serve 0.8% of a population of approximately 265,000, the average size of a CCG. The figure of 0.8% was used as an estimate for the number of people that should receive some level of end of life care services. <a class="figpopup" href="/books/NBK558771/table/ch11.tab10/?report=objectonly" target="object" rid-figpopup="figch11tab10" rid-ob="figobch11tab10">Table 10</a>, provides estimates of the total costs of the services included in the costing analysis. For full details please see the End of Life Care costing analysis report, saved separately on the NICE website.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab10"><a href="/books/NBK558771/table/ch11.tab10/?report=objectonly" target="object" title="Table 10" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab10" rid-ob="figobch11tab10"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab10/?report=thumb" src-large="/books/NBK558771/table/ch11.tab10/?report=previmg" alt="Table 10. Total costs of the out-of-hours community services included in the costing analysis." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab10"><a href="/books/NBK558771/table/ch11.tab10/?report=objectonly" target="object" rid-ob="figobch11tab10">Table 10</a></h4><p class="float-caption no_bottom_margin">Total costs of the out-of-hours community services included in the costing analysis. </p></div></div><p><a class="figpopup" href="/books/NBK558771/table/ch11.tab11/?report=objectonly" target="object" rid-figpopup="figch11tab11" rid-ob="figobch11tab11">Table 11</a> provides estimates of the potential cost savings, per unit reduction in outcome achieved, that might arise from implementing the additional out-of-hours, end-of-life services in the community.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab11"><a href="/books/NBK558771/table/ch11.tab11/?report=objectonly" target="object" title="Table 11" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab11" rid-ob="figobch11tab11"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab11/?report=thumb" src-large="/books/NBK558771/table/ch11.tab11/?report=previmg" alt="Table 11. Potential cost savings resulting from implementing the additional end-of-life out-of-hours community services." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab11"><a href="/books/NBK558771/table/ch11.tab11/?report=objectonly" target="object" rid-ob="figobch11tab11">Table 11</a></h4><p class="float-caption no_bottom_margin">Potential cost savings resulting from implementing the additional end-of-life out-of-hours community services. </p></div></div><p><a class="figpopup" href="/books/NBK558771/table/ch11.tab12/?report=objectonly" target="object" rid-figpopup="figch11tab12" rid-ob="figobch11tab12">Table 12</a> reports the results of the threshold analysis. These results provide estimates of the outcomes the service components would need to achieve to make them cost neutral; assuming they were implemented to serve 0.8% of a population of approximately 265,000.</p><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figch11tab12"><a href="/books/NBK558771/table/ch11.tab12/?report=objectonly" target="object" title="Table 12" class="img_link icnblk_img figpopup" rid-figpopup="figch11tab12" rid-ob="figobch11tab12"><img class="small-thumb" src="/books/NBK558771/table/ch11.tab12/?report=thumb" src-large="/books/NBK558771/table/ch11.tab12/?report=previmg" alt="Table 12. Threshold Analysis Results." /></a><div class="icnblk_cntnt"><h4 id="ch11.tab12"><a href="/books/NBK558771/table/ch11.tab12/?report=objectonly" target="object" rid-ob="figobch11tab12">Table 12</a></h4><p class="float-caption no_bottom_margin">Threshold Analysis Results. </p></div></div><p><i>Interpreting the results:</i> The above table shows that for the care coordination service to be cost neutral, it would need to achieve a 63% reduction in deaths occurring in hospital, or a 6% reduction in inpatient days spent in emergency admissions for people in the last year of life, or a 6% reduction in emergency admissions of people in the last year of life. However, if reductions in the outcomes were to occur simultaneously, as would be likely to happen in reality, then the reduction required for each individual outcome would be lower.</p></div></div><div id="ch11.s1.5"><h3>1.5. Resource costs</h3><p>The recommendations made based on this review (see section <b>Error! Reference source not found.</b>) may have a substantial impact on resources.</p><p>Additional costs could be incurred for the following reasons: the implementation of giving people (thought to be in the last year of life) access to a healthcare practitioner available 24 hours a day, 7 days-a-week, who can access the person’s records and advance care plan, and can make informed decisions about changes to care; a dedicated out-of-hours end of life care advice line; an out-of-hours pharmacy service that has access to medicines for symptom relief in adults in the last year of life. The magnitude of the resource impact depends on the scale to which the above is already current practice for end of life care. This will depend on local circumstances. Savings could be made through hospital admissions and hospital deaths avoided due to improvements in the out-of-hours services available for people in the last year of life. Further detail can be found in the resource impact tools that support the guideline which will be available after final publication.</p></div><div id="ch11.s1.6"><h3>1.6. Evidence statements</h3><div id="ch11.s1.6.1"><h4>1.6.1. Clinical evidence statements</h4><div id="ch11.s1.6.1.1"><h5>People who were offered the service (service available) compared with people who were not offered the service (service not available)</h5><div id="ch11.s1.6.1.1.1"><h5>Rapid response service</h5><p>In carers there was a clinically important difference in favour of people who were not offered the service for carers’ quality of life (EQ-5D) and quality life (SF-36 mental). There was no clinically important difference for carers’ quality of life (SF-36 physical) or for the proportion of people achieving their preferred initial or final actual place of death.</p></div><div id="ch11.s1.6.1.1.2"><h5>Specialist palliative care</h5><p>A clinically important lower proportion of people who were offered the specialist palliative care team died in hospital. The difference between the two groups was not clinically important for the proportion of people who were hospitalised or attended accident and emergency both in the last two weeks of life.</p></div><div id="ch11.s1.6.1.1.3"><h5>Palliative care team</h5><p>For the outcome of preferred place of death in hospital there was a clinically important lower proportion of people who were offered the service compared to people who were not offered the service. There was a clinically importance difference between people who were and people were not offered the service with the former having a greater proportion of people dying in a country hospital and at home. There was no clinically important difference between the groups for the proportion of people dying in a nursing home</p><p>The mean time spent in hospital in the last two months of life was shorter for the people who were offered the service compared to those who were not.</p><p>There was no clinical difference between the groups for the mean number of hospitalisations in the last two months of life.</p></div></div><div id="ch11.s1.6.1.2"><h5>People who were offered the service and used it (users) compared with those that were offered the service but did not use it (non-users)</h5><div id="ch11.s1.6.1.2.1"><h5>Rapid response service</h5><p>There was a clinically important difference in favour of people who used the service for preferred (initial) and actual place of death. A clinically important higher proportion of users had more than one contacts with community services (GP/primary care or community care), one or more visits from a Marie Curie professional or one or more contacts with an out of hours service. There was no clinically important difference between the groups with respect to the proportion of people with one or more visits to accident and emergency, acute care, a hospice or with social services.</p></div><div id="ch11.s1.6.1.2.2"><h5>Delivering Choice Programme</h5><p>For the outcome of actual place of death there was a clinically important difference between users compared to non-users with the former having a lower proportion of people dying in an acute hospital and elsewhere. There was a clinically importance difference between users compared to non-users with the former having a greater proportion of people dying in a community hospital, at home and in hospice. There was no clinically important difference between users compared to non-users for the proportion of people dying in a care home and ‘elsewhere’.</p><p>There was a clinically important difference between users compared to non-users with the former having a lower proportion of people with one or more emergency admissions and visits to the accident and emergency department within the last 30 and 7days.</p><p>There was no clinically important difference between users compared to non-users for the proportion of people for the mean number of patients with one more emergency admissions, visits to the accident and emergency department per patient at 30 and 7 days.</p></div></div><div id="ch11.s1.6.1.3"><h5>People who were offered the service and used it with those who were offered the same service without ‘out of hours’ element</h5><div id="ch11.s1.6.1.3.1"><h5>Delivering Choice Programme</h5><p>There was a clinically important difference between people who used the service compared to users of a non-‘out of hours’ service for actual place of death with lower proportion of people dying in an acute hospital, a care home and ‘elsewhere’ and a greater proportion of people dying at home. The difference between the users of both services for the proportion of people dying in a hospice was not clinically important.</p><p>A clinically important lower proportion of users of the ‘out of hours’ service compared to an emergency hospital admissions within 30 days and 7 days of death.</p><p>There was no clinically important difference between the groups for the proportion of people with visiting the accident and emergency department within 30 days and 7 days of death, the mean number of visits to the accident and emergency department or mean number of hospital visits per patient within 30 days and 7 days of death</p></div></div></div><div id="ch11.s1.6.2"><h4>1.6.2. Health economic evidence statements</h4><p>No relevant economic evaluations were identified.</p><p>The threshold analysis conducted on different ‘out of hours’ community end of life services found that the services would be considered good value of money for the average CCG if they achieved:
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<ul id="ch11.l3"><li id="ch11.lt14" class="half_rhythm"><div>Care coordination service:
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<ul id="ch11.l4" class="circle"><li id="ch11.lt15" class="half_rhythm"><div>61% reduction in number of hospital deaths, or</div></li><li id="ch11.lt16" class="half_rhythm"><div>6% reduction in emergency inpatient days of people in the last year of life, or</div></li><li id="ch11.lt17" class="half_rhythm"><div>6% reduction in emergency admissions of people in the last year of life</div></li></ul></div></li><li id="ch11.lt18" class="half_rhythm"><div>Out-of-hours end-of-life advice line:
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<ul id="ch11.l5" class="circle"><li id="ch11.lt19" class="half_rhythm"><div>13% reduction in number of hospital deaths, or</div></li><li id="ch11.lt20" class="half_rhythm"><div>1% reduction in emergency inpatient days of people in the last year of life, or</div></li><li id="ch11.lt21" class="half_rhythm"><div>1% reduction in emergency admissions of people in the last year of life</div></li></ul></div></li><li id="ch11.lt22" class="half_rhythm"><div>Out-of-hours end-of-life Pharmacy service:
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<ul id="ch11.l6" class="circle"><li id="ch11.lt23" class="half_rhythm"><div>1% reduction in number of hospital deaths, or</div></li><li id="ch11.lt24" class="half_rhythm"><div>0.06% reduction in emergency inpatient days of people in the last year of life, or</div></li><li id="ch11.lt25" class="half_rhythm"><div>0.06% reduction in emergency admissions of people in the last year of life</div></li></ul></div></li><li id="ch11.lt26" class="half_rhythm"><div>End-of-life ambulance service
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<ul id="ch11.l7" class="circle"><li id="ch11.lt27" class="half_rhythm"><div>10% reduction in number of hospital deaths, or</div></li><li id="ch11.lt28" class="half_rhythm"><div>1% reduction in emergency inpatient days of people in the last year of life, or</div></li><li id="ch11.lt29" class="half_rhythm"><div>1% reduction in emergency admissions of people in the last year of life</div></li></ul></div></li><li id="ch11.lt30" class="half_rhythm"><div>Hospice at home
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<ul id="ch11.l8" class="circle"><li id="ch11.lt31" class="half_rhythm"><div>83% reduction in number of hospital deaths, or</div></li><li id="ch11.lt32" class="half_rhythm"><div>8% reduction in emergency inpatient days of people in the last year of life, or</div></li><li id="ch11.lt33" class="half_rhythm"><div>8% reduction in emergency admissions of people in the last year of life</div></li></ul></div></li></ul></p></div></div><div id="ch11.s1.7"><h3>1.7. The committee’s discussion of the evidence</h3><div id="ch11.s1.7.1"><h4>1.7.1. Interpreting the evidence</h4><div id="ch11.s1.7.1.1"><h5>1.7.1.1. The outcomes that matter most</h5><p>The committee identified quality of life, and preferred place of care and death as the critical outcomes for measuring the impact of an ‘out of hours’ service. The following outcomes were identified as important: length of stay, length of survival, hospitalisation, number of hospital visits, number of visits to accident and emergency, number of unscheduled admissions, use of community services, avoidable or inappropriate admissions to ICU, inappropriate attempts at cardiopulmonary resuscitation, staff satisfaction, patient or carer reported outcomes and carer health.</p><p>See <a class="figpopup" href="/books/NBK558771/table/ch11.tab7/?report=objectonly" target="object" rid-figpopup="figch11tab7" rid-ob="figobch11tab7">tables 7</a> and <a class="figpopup" href="/books/NBK558771/table/ch11.tab8/?report=objectonly" target="object" rid-figpopup="figch11tab8" rid-ob="figobch11tab8">8</a> in the Methods chapter for a detailed explanation of why the committee selected these outcomes.</p><p>For the critical outcomes only one study reported the quality of life of carers. Only one study reported actual and preferred place of death with the remainder reporting actual place of death.</p><p>For the important outcomes one study reported length of hospital stay. All five studies (two studies on the same data set) reported one or more outcomes related to accident and emergency visits or hospitalisation. None of the studies reported whether these were unscheduled or avoidable. One study reported use of community services. None of the studies reported length of survival. No studies reported inappropriate or avoidable admissions to ICU, inappropriate attempts at cardiopulmonary resuscitation or staff satisfaction.</p><p>Place of death was a surrogate outcome for actual place of death compared to preferred place of death.</p></div><div id="ch11.s1.7.1.2"><h5>1.7.1.2. The quality of the evidence</h5><p>All of the studies had an observational design and the quality of the evidence ranged from very low to low. The Committee was unable to pre-specify confounders that may affect the results of the studies. Some of the studies performed multivariate analysis but only included a limited number of potential confounders.</p><p>One study was considered to have an indirect population and the evidence downgraded because the population was restricted to people with cancer. A number of the studies did not describe the comparator i.e., standard care and more specifically they did not describe whether an ‘out of hours’ service was available or not. This meant that it was impossible to understand what was making a difference in the interventions.</p></div><div id="ch11.s1.7.1.3"><h5>1.7.1.3. Benefits and harms</h5><p>One study evaluated an ‘out of hours’ service only (rapid response service). The results are in favour of the intervention for a limited number of outcomes for preferred (initial) and actual place of death, more than one contact with community services (GP/primary care or community care), one or more visits from a Marie Curie professional or one or more contacts with an out of hours service.</p><p>The remaining studies implemented a number of services changes in addition to an out of hours service. The Committee was not confident that an ‘out of hours’ service implemented in isolation would lead to clinically important benefits. The Committee noted that an ‘out of hours’ service was unlikely to be implemented in isolation and that the evidence reflected the type of services that currently exist in the UK. The Committee acknowledged the variation in these different ‘out of hours’ services across the UK.</p><p>The Committee noted that it was difficult to interpret the evidence where there were few people using the out of hours service compared to the people who had access to it.</p><p>There may be differences between the groups for a number of reasons, for example the severity of illness and symptoms and the availability of support from people important to the person who is in their last year of life. These variables were either not reported at baseline or the analysis was restricted to a small number of confounders. The studies comparing those who were and who were not offered the service were difficult to interpret as the comparator or standard care was poorly described especially with respect to whether any ‘out of hours’ service was available.</p><p>The Committee noted that the majority of people included in the studies had cancer and this is not representative of the people who actually use the service for example older adults with deteriorating health or people with chronic conditions with deteriorating health.</p><p>The Committee agreed that the evidence from the study comparing people who were offered the service and used it with people who were offered the service without the ‘out of hours’ element and used it was the most relevant. Whilst this study only adjusted for a limited number of potential confounders the characteristics of the people in each group were likely to be comparable.</p><p>There was one study comparing people who were and were not offered the service that reported whether people died in their initial preferred place of death and the final preferred place of death. The results were in favour of the intervention. Both the initial and final preferred place of death was at home.</p><p>The lower proportion of people accessing hospital services in the study comparing people who were offered the service and used it with those who were offered the service without out of hours and used it was thought to be due to the ability of the service to manage symptoms at home.</p><p>The evidence reporting use of acute and community services for people who were offered the service and used it with those who were offered the service and did not use it showed an increase in service use. The Committee commented that people who use a service have a greater need for example a more symptomatic and may therefore require more support from services. Alternatively, the out of hours service may identify symptom needs to be managed in hospital or that additional community services may be required.</p></div></div><div id="ch11.s1.7.2"><h4>1.7.2. Cost effectiveness and resource use</h4><p>Having services available to access out-of-hours (for example extended hours, available at weekends or 24/7) increases the amount of resources required (for example staff time or overhead costs) to provide the services compared to if they were only available Monday to Friday, 9am to 5pm. The committee discussed the possibility that some out-of-hours services do however have the potential to save NHS resources. This might be through helping to prevent costly emergency hospital admissions, or increasing the feasibility that people can be cared for in their preferred place of care or the likelihood that people will be able to die outside hospital. The committee noted that in order to ensure 24/7 care is clinically and cost effective in addressing patients’ needs, practitioners need access to the person’s records and advance care plan, preferably through a shared electronic information system, to enable them to make informed decisions about care.</p><p>The committee discussed the example of having equipment provision services available out-of-hours, for example at weekends, would reduce a number of unnecessary hospital admissions where people are admitted to hospital because they cannot get access to certain equipment which had they had access, would have prevented the admission. Another example the committee discussed was people having access to end-of-life medications out-of-hours. Currently, if people cannot be issued with end-of-life medications out of hours, they will be admitted to hospital in an emergency, where they are then potentially at a greater risk of developing complications such as a hospital infection. Avoidable admissions are considered an inefficient use of resources as well as inducing unnecessary stress and discomfort for the patients and those close to them. With the end-of-life population there is also the potential risk that people admitted to hospital may never be discharged.</p><p>The committee highlighted that currently there is huge national variation in what end of life services are available out-of-hours. They all agreed that reducing this variation by increasing the level of out-of-hours services available in areas where there is currently very few services available would be likely to be of great benefit as the services would help to support a service model that enables and empowers people to choose to be cared for outside of a hospital setting; however the committee also acknowledged the significant resource impact of recommending out-of-hours services due to the increased level of resources required to provide the services compared to current practice.</p><p>The committee felt that community services and out-of-hours services were extremely important areas of the guideline where any potential recommendations would be likely to lead to a significant resource impact; therefore they were prioritised as areas for original economic analysis. Due to the low quality of the clinical evidence it was not possible to conduct an evidence based cost-effectiveness analysis. A cost analysis was conducted for different out-of-hours community interventions that had been identified by the committee, from the literature or from the call for evidence (please see the details of the analysis in the Appendix 1 on the NICE website). The committee identified deaths occurring outside hospital, length of stay in end of life emergency admissions and emergency admissions as the outcomes for the analysis. The cost analysis also included a threshold analysis which determined the reductions required in outcomes listed above, for a hypothetical region representing an average size CCG, to make the services cost neutral.</p><p>The committee used the results of the threshold analysis to inform their recommendations regarding having an out-of-hours advice line dedicated to end of life, a dedicated ambulance services for end of life patients, and an out-of-hours end-of-life pharmacy service as the committee felt confident that the outcomes needed to recover the costs of these interventions could be achieved, and therefore felt the interventions were likely to be a good use of NHS resources. The committee felt more uncertain about whether the care coordination service and hospice at home components would be able to achieve the required outcomes needed to make them cost neutral.</p><p>It is important to note that the illustrative costs provided in the cost analysis that were presented to the committee to aid the decisions were highly subjective and do not reflect the estimated actual cost of implementing the services. In reality the costs will vary significantly according to the specific region and are therefore extremely difficult to estimate.</p><p>The committee noted that geographical, societal, economic and epidemiological differences between regions mean that the optimal end-of-life service model will differ by locality and will be determined by a number of varying factors. The committee also noted that due to wide scale variation in the level of services currently available, the level of reorganisation required would need to be tailored to compliment what is currently already provided, and the resource impact of any recommendations will depend on this as well.</p></div><div id="ch11.s1.7.3"><h4>1.7.3. Other factors the committee took into account</h4><p>Although the committee recommended access to out of hours pharmacy they were aware that some services have arrangements for the anticipatory prescribing of end of life medication and this been described as having a positive impact on reducing the need for people needing emergency pharmacy services.</p></div></div></div><div id="ch11.rl.r1"><h2 id="_ch11_rl_r1_">References</h2><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="ch11.ref1">Adam
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E, Finucane
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A, Kendall
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M. Understanding the barriers to identifying carers of people with advanced illness in primary care: Triangulating three data sources. BMC Family Practice. 2014; 14:48 [<a href="/pmc/articles/PMC3992158/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3992158</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24690099" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24690099</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>30.</dt><dd><div class="bk_ref" id="ch11.ref30">Carlebach
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S, Shucksmith
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J. A review of an out-of-hours telephone support service for palliative care patients and their families. International Journal of Palliative Nursing. 2010; 16(9):445–50 [<a href="https://pubmed.ncbi.nlm.nih.gov/20871499" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20871499</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>31.</dt><dd><div class="bk_ref" id="ch11.ref31">Carr
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SM, Lhussier
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M, Wilcockson
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J. Transferring palliative care knowledge: evaluating the use of a telephone advice line. International Journal of Palliative Nursing. 2008; 14(6):303–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/18928135" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18928135</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>32.</dt><dd><div class="bk_ref" id="ch11.ref32">Casarett
|
|
D, Pickard
|
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A, Bailey
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FA, Ritchie
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C, Furman
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C, Rosenfeld
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K
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C, Johnson
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J. Implementation and evaluation of a rapid access palliative clinic in a New Zealand cancer centre. Journal of Medical Radiation Sciences. 2014; 61(4):217–224 [<a href="/pmc/articles/PMC4282077/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4282077</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25598974" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25598974</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>34.</dt><dd><div class="bk_ref" id="ch11.ref34">Collier
|
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A, Morgan
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DD, Swetenham
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K, To
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TH, Currow
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DC, Tieman
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JJ. Implementation of a pilot telehealth programme in community palliative care: A qualitative study of clinicians’ perspectives. Palliative Medicine. 2016; 30(4):409–17 [<a href="https://pubmed.ncbi.nlm.nih.gov/26290500" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26290500</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>35.</dt><dd><div class="bk_ref" id="ch11.ref35">Connolly
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J, Milligan
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S, Stevens
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E. Advance care planning in a community setting. Nursing Standard. 2015; 29(23):43–51 [<a href="https://pubmed.ncbi.nlm.nih.gov/25649602" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25649602</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>36.</dt><dd><div class="bk_ref" id="ch11.ref36">Costantini
|
|
M, Higginson
|
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IJ, Boni
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L, Orengo
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MA, Garrone
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E, Henriquet
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G, Bouleuc
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C, Gridel
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G, Copel
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L. Impact of a palliative day care unit on advanced cancer patient life’s journey. Palliative Medicine. 2010; 24:(Suppl 4):S195</div></dd></dl><dl class="bkr_refwrap"><dt>38.</dt><dd><div class="bk_ref" id="ch11.ref38">Dawson
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A, Bowes
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A, Kelly
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F, Velzke
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K, Ward
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R. Evidence of what works to support and sustain care at home for people with dementia: A literature review with a systematic approach. BMC Geriatrics. 2015; 15:59 [<a href="/pmc/articles/PMC4465454/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4465454</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25967742" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25967742</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>39.</dt><dd><div class="bk_ref" id="ch11.ref39">De Bock
|
|
GH, Van Kampen
|
|
IM, Van der Goot
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JH, Hamstra
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M, Dekker
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JH, Schuit
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KW
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|
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BL, Arango
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JF, Batiz
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|
J, Gomez
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J, Arrazubi
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V, Sebastian
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KS
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Suppl 1):45</div></dd></dl><dl class="bkr_refwrap"><dt>41.</dt><dd><div class="bk_ref" id="ch11.ref41">Detering
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K, Hancock
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A, Reade
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M. The impact of advance care planning on end of life care in elderly patients: randomised controlled trial. BMJ. 2010; 340(7751):c1345 [<a href="/pmc/articles/PMC2844949/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2844949</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/20332506" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20332506</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>42.</dt><dd><div class="bk_ref" id="ch11.ref42">Dhiliwal
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SR, Muckaden
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M. Impact of specialist home-based palliative care services in a tertiary oncology set up: A prospective non-randomized observational study. Indian Journal of Palliative Care. 2015; 21(1):28–34 [<a href="/pmc/articles/PMC4332123/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4332123</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25709182" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25709182</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>43.</dt><dd><div class="bk_ref" id="ch11.ref43">DiMartino
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LD, Weiner
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BJ, Mayer
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DK, Jackson
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GL, Biddle
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AK. Do palliative care interventions reduce emergency department visits among patients with cancer at the end of life? A systematic review. Journal of Palliative Medicine. 2014; 17(12):1384–99 [<a href="https://pubmed.ncbi.nlm.nih.gov/25115197" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25115197</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>44.</dt><dd><div class="bk_ref" id="ch11.ref44">Doolittle
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GC. A cost measurement study for a home-based telehospice service. Journal of Telemedicine and Telecare. 2000; 6 (Suppl. 1):S193–5 [<a href="https://pubmed.ncbi.nlm.nih.gov/10794017" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10794017</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>45.</dt><dd><div class="bk_ref" id="ch11.ref45">Doolittle
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GC, Yaezel
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A, Otto
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F, Clemens
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C. Hospice care using home-based telemedicine systems. Journal of Telemedicine and Telecare. 1998; 4 (Suppl. 1):58–9 [<a href="https://pubmed.ncbi.nlm.nih.gov/9640738" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 9640738</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>46.</dt><dd><div class="bk_ref" id="ch11.ref46">Downar
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J, Barua
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R, Rodin
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D, Lejnieks
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B, Gudimella
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R, McCredie
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AP, Bemben
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NM, Li
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J, Trovato
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J. Facilitating Home Hospice Transitions of Care in Oncology: Evaluation of Clinical Pharmacists’ Interventions, Hospice Program Satisfaction, and Patient Representation Rates. American Journal of Hospice & Palliative Medicine. 2018; 35(9):1181–1187 [<a href="https://pubmed.ncbi.nlm.nih.gov/29621893" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29621893</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>48.</dt><dd><div class="bk_ref" id="ch11.ref48">Emanuel
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L, Barry
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M, Stoeckle
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J, Ettelson
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LM, Emanuel
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E. Advance directives for medical care a case for greater use. New England Journal of Medicine. 1991; 324(13):889–895 [<a href="https://pubmed.ncbi.nlm.nih.gov/2000111" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 2000111</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>49.</dt><dd><div class="bk_ref" id="ch11.ref49">Enguidandos
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SM, Cherin
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L, Kinley
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J, Hockley
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J. The cost of providing end of life care for nursing care home residents: A retrospective cohort study. Health Services Management Research. 2015; 28(1-2):16–23</div></dd></dl><dl class="bkr_refwrap"><dt>51.</dt><dd><div class="bk_ref" id="ch11.ref51">Fergus
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DJ, Murray
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SA. Assessing and improving out-of-hours palliative care in a deprived community: A rapid appraisal study. Palliative Medicine. 2010; 24(5):493–500 [<a href="https://pubmed.ncbi.nlm.nih.gov/20015922" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20015922</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>52.</dt><dd><div class="bk_ref" id="ch11.ref52">Finlay
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IG. Developing a template to plan palliative care services: The Welsh experience. Journal of Pain and Symptom Management. 2009; 38(1):81–6 [<a href="https://pubmed.ncbi.nlm.nih.gov/19615631" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19615631</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>53.</dt><dd><div class="bk_ref" id="ch11.ref53">Fontaine
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L. A qualitative study of older people’s views of out-of-hours services. British Journal of General Practice. 2001; 51(470):719–723 [<a href="/pmc/articles/PMC1314099/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1314099</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/11593832" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11593832</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>55.</dt><dd><div class="bk_ref" id="ch11.ref55">Fredheim
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OM, Kaasa
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S, Fayers
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P, Saltnes
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T, Jordhoy
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M, Borchgrevink
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PC. Chronic non-malignant pain patients report as poor health-related quality of life as palliative cancer patients. Acta Anaesthesiologica Scandinavica. 2008; 52(1):143–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/18005378" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18005378</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>56.</dt><dd><div class="bk_ref" id="ch11.ref56">Fukui
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S, Fujita
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J, Tsujimura
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M, Sumikawa
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Y, Hayashi
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Y, Fukui
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H, Holdsworth
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LM, Flannery
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C, Williams
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P, Butler
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C. Impact of a hospice rapid response service on preferred place of death, and costs. BMC Palliative Care. 2015; 14:75 [<a href="/pmc/articles/PMC4688966/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4688966</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26701763" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26701763</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>58.</dt><dd><div class="bk_ref" id="ch11.ref58">Gallagher
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FM, 3rd, Schwartz
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D, Schmidt
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L, Krasnik
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B, Calanzani
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N, Curiale
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V, McCrone
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P, Higginson
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IJ. Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers. Cochrane Database of Systematic Reviews
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B, Cohen
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J, Deliens
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L, Higginson
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I. International trends in circumstances of death and dying among older people. Living with ageing and dying: Oxford University Press. 2011. p. 3–18.</div></dd></dl><dl class="bkr_refwrap"><dt>63.</dt><dd><div class="bk_ref" id="ch11.ref63">Gomes
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B, Higginson
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IJ. Evidence on home palliative care: Charting past, present, and future at the cicely saunders institute - WHO collaborating centre for palliative care, policy and rehabilitation. Progress in Palliative Care. 2013; 21(4):204–213</div></dd></dl><dl class="bkr_refwrap"><dt>64.</dt><dd><div class="bk_ref" id="ch11.ref64">Grabowski
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A, Travers
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GE, Farquhar
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MC, Barclay
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SI, Todd
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CJ. Caregiver bereavement outcome: relationship with hospice at home, satisfaction with care, and home death. Journal of Palliative Care. 2004; 20(2):69–77 [<a href="https://pubmed.ncbi.nlm.nih.gov/15332470" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15332470</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>68.</dt><dd><div class="bk_ref" id="ch11.ref68">Grande
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GE, Todd
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SIG, Farquhar
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MC. A randomized controlled trial of a hospital at home service for the terminally ill. Palliative Medicine. 2000; 14(5):375–85 [<a href="https://pubmed.ncbi.nlm.nih.gov/11064784" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11064784</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>69.</dt><dd><div class="bk_ref" id="ch11.ref69">Grogan
|
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E, Paes
|
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P, Peel
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S, Davies
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A. An evaluation of the activity of a 7-day, nurse-led specialist palliative care service in an acute district general hospital. International Journal of Palliative Nursing. 2013; 19(3):148–50 [<a href="https://pubmed.ncbi.nlm.nih.gov/23665573" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23665573</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>71.</dt><dd><div class="bk_ref" id="ch11.ref71">Hanks
|
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GW, Robbins
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M, Sharp
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D, Forbes
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K, Done
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K, Peters
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TJ
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JT, Burger
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SG. They are called nursing homes for a reason: RN staffing in long-term care facilities. Journal of Gerontological Nursing. 2015; 41(12):15–20 [<a href="https://pubmed.ncbi.nlm.nih.gov/26594951" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26594951</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>73.</dt><dd><div class="bk_ref" id="ch11.ref73">Harvey
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C, Gunnerson
|
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K, Kessler
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R, Litell
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J, Whitmore
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S, Havey
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L, Lopes
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AJ, Araujo
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JA, Petersen
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EM, Nunes
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RA. The assessment of telemedicine to support outpatient palliative care in advanced cancer. Palliative & Supportive Care. 2015; 13(4):1025–30 [<a href="https://pubmed.ncbi.nlm.nih.gov/25159308" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25159308</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>75.</dt><dd><div class="bk_ref" id="ch11.ref75">Herrera
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E, Nuno
|
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R, Cabrera
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A, Librada
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S, Rodriguez-Pereira
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C, Orueta
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JF
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et al. Impact of a home-based social welfare program on care for palliative patients in the basque country (SAIATU program). Palliative Medicine. 2014; 28 (6):674 [<a href="/pmc/articles/PMC3576230/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3576230</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23363526" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23363526</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>76.</dt><dd><div class="bk_ref" id="ch11.ref76">Hoexum
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M, Bosveld
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HE, Schuling
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J, Berendsen
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AJ. Out-of-hours medical care for terminally ill patients: A survey of availability and preferences of general practitioners. Palliative Medicine. 2012; 26(8):986–93 [<a href="https://pubmed.ncbi.nlm.nih.gov/22126846" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22126846</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>77.</dt><dd><div class="bk_ref" id="ch11.ref77">Holdsworth
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LM, Gage
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H, Coulton
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S, King
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A, Butler
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|
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DE, Vanderboom
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CE, Ingram
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CJ, Dose
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AM, Borkenhagen
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LS, Skadahl
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DE, Street
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AF, Sands
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|
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TB, Hernandez
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AF, Liang
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L, Albert
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NM, Labresh
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KA, Yancy
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CW
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CHM, Spruit
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MA, Wouters
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SY. Implementing inter-professional practice model improves palliative care in terminal breast cancer woman. European Journal of Cancer. 2016; 57:S29</div></dd></dl><dl class="bkr_refwrap"><dt>83.</dt><dd><div class="bk_ref" id="ch11.ref83">Hughes
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SL, Cummings
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LM, Conrad
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KJ, Nash
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|
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SL, Weaver
|
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FM, Giobbie-Hurder
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A, Manheim
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L, Henderson
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W, Kubal
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JD
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L, Giesen
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P, Wensing
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M, Grol
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R. Out-of-hours care in western countries: Assessment of different organizational models. BMC Health Services Research. 2009; 9
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105 [<a href="/pmc/articles/PMC2717955/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2717955</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19549325" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19549325</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>86.</dt><dd><div class="bk_ref" id="ch11.ref86">Hull
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MM. Hospice nurses. Caring support for caregiving families. Cancer Nursing. 1991; 14(2):63–70 [<a href="https://pubmed.ncbi.nlm.nih.gov/2044063" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 2044063</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>87.</dt><dd><div class="bk_ref" id="ch11.ref87">Jacobsen
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J, Jackson
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V, Dahlin
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C, Greer
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J, Perez-Cruz
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P, Billings
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JA
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B, Kidd
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L, Wengstrom
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Y, Kearney
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N. An evaluation of the use of Telehealth within palliative care settings across Scotland. Palliative Medicine. 2012; 26(2):152–61 [<a href="https://pubmed.ncbi.nlm.nih.gov/21378067" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21378067</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>89.</dt><dd><div class="bk_ref" id="ch11.ref89">Jones
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DA, McIntyre
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T, Baldwin
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R. The medical emergency team and end-of-life care: a pilot study. Critical Care and Resuscitation. 2007; 9(2):151–6 [<a href="https://pubmed.ncbi.nlm.nih.gov/17536983" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17536983</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>90.</dt><dd><div class="bk_ref" id="ch11.ref90">Joseph
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R, Brown-Manhertz
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D, Ikwuazom
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S, Singleton
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JK. The effectiveness of structured interdisciplinary collaboration for adult home hospice patients on patient satisfaction and hospital admissions and re-admissions: a systematic review. JBI Database Of Systematic Reviews And Implementation Reports. 2016; 14(1):108–139 [<a href="https://pubmed.ncbi.nlm.nih.gov/26878925" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26878925</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>91.</dt><dd><div class="bk_ref" id="ch11.ref91">Kassakian
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MG, Bailey
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M, Stewart
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CA, Yates
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JW. The cost and quality of dying: A comparison of home and hospital. Nurse Practitioner. 1979; 4(1):18–9, 22–3 [<a href="https://pubmed.ncbi.nlm.nih.gov/759999" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 759999</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>92.</dt><dd><div class="bk_ref" id="ch11.ref92">Kendall
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C, Jeffrey
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C, Hawker
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M, Seamark
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D. Out-of-hours medical cover in community hospitals: Implications for palliative care. International Journal of Palliative Nursing. 2006; 12(2):75–80 [<a href="https://pubmed.ncbi.nlm.nih.gov/16603996" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16603996</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>94.</dt><dd><div class="bk_ref" id="ch11.ref94">King
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G, Mackenzie
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H, Clark
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D. Dying at home: Evaluation of a hospice rapid-response service. International Journal of Palliative Nursing. 2000; 6(6):280–7 [<a href="https://pubmed.ncbi.nlm.nih.gov/11249449" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11249449</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>95.</dt><dd><div class="bk_ref" id="ch11.ref95">King
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CA, Howell
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G, Jordan
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T, Richardson
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V, Samsi
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D, Banerjee
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A, Baumoehl
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Y, Habot
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B, Gil
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SH, Chan
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CY, Chan
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CH, Sze
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WK, Yuen
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KK, Wong
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C, Garavaglia
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G, Borghi
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G, Castelli
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A, Radaelli
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G, Peruselli
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C. Implementation of a hospital-based home palliative care at regional level: A quantitative study of the Ospedalizzazione Domiciliare Cure Palliative Oncologiche program in Lombardy. Palliative Medicine. 2015; 29(3):241–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/25524959" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25524959</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>111.</dt><dd><div class="bk_ref" id="ch11.ref111">McCorkle
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R, Benoliel
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JQ, Donaldson
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G, Georgiadou
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F, Moinpour
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C, Goodell
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B. A randomized clinical trial of home nursing care for lung cancer patients. Cancer. 1989; 64(6):1375–82 [<a href="https://pubmed.ncbi.nlm.nih.gov/2670188" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 2670188</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>112.</dt><dd><div class="bk_ref" id="ch11.ref112">McWhinney
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IR, Bass
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MJ, Donner
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A. Evaluation of a palliative care service: problems and pitfalls. BMJ. 1994; 309(6965):1340–2 [<a href="/pmc/articles/PMC2541867/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2541867</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/7532501" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 7532501</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>113.</dt><dd><div class="bk_ref" id="ch11.ref113">Meier
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ML, Neuenschwander
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LL, Hornbrook
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MC, Archbold
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PG, Stewart
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BJ. Development of use and cost measures in a nursing intervention for family caregivers and frail elderly patients. Research in Nursing and Health. 1996; 19(4):273–85 [<a href="https://pubmed.ncbi.nlm.nih.gov/8773551" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8773551</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>115.</dt><dd><div class="bk_ref" id="ch11.ref115">Mitchell
|
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G, Cherry
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M, Kennedy
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R, Weeden
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K, Burridge
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L, Clavarino
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A
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G, Zhang
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J, Burridge
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L, Senior
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H, Miller
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E, Young
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S
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et al. Case conferences between general practitioners and specialist teams to plan end of life care of people with end stage heart failure and lung disease: an exploratory pilot study. BMC Palliative Care. 2014; 13:24 [<a href="/pmc/articles/PMC4020309/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4020309</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24829539" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24829539</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>117.</dt><dd><div class="bk_ref" id="ch11.ref117">Mohren
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U, Mohren
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M, Nellessen
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U. Implementation of specialised outpatient palliative care (SAPV) in Northern Sachsen-Anhalt, Germany: A challenging task. Onkologie. 2011; 34:52</div></dd></dl><dl class="bkr_refwrap"><dt>118.</dt><dd><div class="bk_ref" id="ch11.ref118">Molina
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EH, Nuno-Solinis
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R, Idioaga
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GE, Flores
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SL, Hasson
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N, Orueta Media
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JF. Impact of a home-based social welfare program on care for palliative patients in the Basque Country (SAIATU Program). BMC Palliative Care. 2013; 12:3 [<a href="/pmc/articles/PMC3576230/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3576230</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23363526" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23363526</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>119.</dt><dd><div class="bk_ref" id="ch11.ref119">Munday
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D, Dale
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J, Barnett
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M. Out-of-hours palliative care in the UK: Perspectives from general practice and specialist services. Journal of the Royal Society of Medicine. 2002; 95(1):28–30 [<a href="/pmc/articles/PMC1279144/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1279144</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/11773348" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11773348</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>120.</dt><dd><div class="bk_ref" id="ch11.ref120">National End of Life Care Intelligence Network. What do we know now that we didn’t know a year ago?
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National End of Life Care Intelligence Network, 2012. Available from: <a href="http://www.endoflifecareintelligence.org.uk/resources/publications/what_we_know_now" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.endoflifecareintelligence<wbr style="display:inline-block"></wbr>​.org<wbr style="display:inline-block"></wbr>​.uk/resources/publications<wbr style="display:inline-block"></wbr>​/what_we_know_now</a></div></dd></dl><dl class="bkr_refwrap"><dt>121.</dt><dd><div class="bk_ref" id="ch11.ref121">National Institute for Health and Care Excellence. Developing NICE guidelines: the manual. London. National Institute for Health and Care Excellence, 2014. Available from: <a href="http://www.nice.org.uk/article/PMG20/chapter/1%20Introduction%20and%20overview" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.nice.org.uk<wbr style="display:inline-block"></wbr>​/article/PMG20/chapter<wbr style="display:inline-block"></wbr>​/1%20Introduction%20and%20overview</a> [<a href="https://pubmed.ncbi.nlm.nih.gov/26677490" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26677490</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>122.</dt><dd><div class="bk_ref" id="ch11.ref122">Neergaard
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MA, Vedsted
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P, Olesen
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F, Sokolowski
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I, Jensen
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AB. Associations between home death and GP involvement in palliative cancer care. British Journal of General Practice. 2009; 59(566):671–7 [<a href="/pmc/articles/PMC2734355/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2734355</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19761666" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19761666</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>123.</dt><dd><div class="bk_ref" id="ch11.ref123">Niemeyer-Guimaraes
|
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M, D’Araujo
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J, Laeta
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R, Lima
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S, Migon
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L, Martins
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D. Implementation of a palliative care service model in a tertiary hospital in Rio De Janeiro, Brazil. Journal of the American Geriatrics Society. 2016; 64(Special 1):S39–S40</div></dd></dl><dl class="bkr_refwrap"><dt>124.</dt><dd><div class="bk_ref" id="ch11.ref124">Noble
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B, Hughes
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P, Ingleton
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C, Berg
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J, Clark
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D. Impact of the Powys Macmillan GP clinical facilitator project: Views of health-care professionals. International Journal of Palliative Nursing. 2003; 9(12):528–33 [<a href="https://pubmed.ncbi.nlm.nih.gov/14765009" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 14765009</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>125.</dt><dd><div class="bk_ref" id="ch11.ref125">Noble
|
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B, King
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N, Woolmore
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A, Hughes
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P, Winslow
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M, Melvin
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J
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et al. Can comprehensive specialised end-of-life care be provided at home? Lessons from a study of an innovative consultant-led community service in the UK. European Journal of Cancer Care. 2015; 24(2):253–66 [<a href="/pmc/articles/PMC4359037/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4359037</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24735122" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24735122</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>126.</dt><dd><div class="bk_ref" id="ch11.ref126">Nyatanga
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B. The impact of out-of-hours service provision on end-of-life care. British Journal of Community Nursing. 2013; 18(3):132 [<a href="https://pubmed.ncbi.nlm.nih.gov/23653961" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23653961</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>127.</dt><dd><div class="bk_ref" id="ch11.ref127">Pesut
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B, Hooper
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BP, Robinson
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CA, Bottorff
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JL, Sawatzky
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R, Dalhuisen
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M. Feasibility of a rural palliative supportive service. Rural & Remote Health. 2015; 15(2):3116 [<a href="https://pubmed.ncbi.nlm.nih.gov/25939666" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25939666</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>128.</dt><dd><div class="bk_ref" id="ch11.ref128">Phillips
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JL, Davidson
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PM, Newton
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PJ, Digiacomo
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M. Supporting patients and their caregivers after-hours at the end of life: The role of telephone support. Journal of Pain and Symptom Management. 2008; 36(1):11–21 [<a href="https://pubmed.ncbi.nlm.nih.gov/18411012" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18411012</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>129.</dt><dd><div class="bk_ref" id="ch11.ref129">Pimentel
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LE, Yennurajalingam
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S, Chisholm
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GB, Edwards
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T, Guerra-Sanchez
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M, De La Cruz
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MGJ
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et al. Impact of a dedicated supportive care center telephone triaging program (SCCTP) for patients with advanced cancer. Journal of Clinical Oncology Conference: ASCO’s Quality Care Symposium. 2013; 31:(Suppl 1):54</div></dd></dl><dl class="bkr_refwrap"><dt>130.</dt><dd><div class="bk_ref" id="ch11.ref130">Plummer
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S, Allan
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R. Analysis of a network-wide specialist palliative care out-of-hours advice and support line: A model for the future. International Journal of Palliative Nursing. 2011; 17(10):494–499 [<a href="https://pubmed.ncbi.nlm.nih.gov/22068119" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22068119</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>131.</dt><dd><div class="bk_ref" id="ch11.ref131">Porzio
|
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G, Aielli
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F, Verna
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L, Martella
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F, Aloisi
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P, Ficorella
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C. Integrating oncology and palliative home care in Italy: The experience of the “L’Aquila per la Vita” Home Care Unit. Tumori. 2013; 99(2):225–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/23748818" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23748818</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>132.</dt><dd><div class="bk_ref" id="ch11.ref132">Public Health England. End of life care economic tool. Public Health England, 2017. Available from: <a href="https://www.gov.uk/government/publications/end-of-life-careeconomic-tool" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.gov.uk/government<wbr style="display:inline-block"></wbr>​/publications<wbr style="display:inline-block"></wbr>​/end-of-life-careeconomic-tool</a></div></dd></dl><dl class="bkr_refwrap"><dt>133.</dt><dd><div class="bk_ref" id="ch11.ref133">Purdy
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S, Lasseter
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G, Griffin
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T, Wye
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L. Impact of the Marie Curie Cancer Care Delivering Choice Programme in Somerset and North Somerset on place of death and hospital usage: a retrospective cohort study. BMJ Supportive & Palliative Care. 2015; 5(1):34–9 [<a href="/pmc/articles/PMC4345906/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4345906</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24838731" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24838731</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>134.</dt><dd><div class="bk_ref" id="ch11.ref134">Reineck
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LA, Wallace
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DJ, Barnato
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AE, Kahn
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JM. Nighttime intensivist staffing and the timing of death among ICU decedents: A retrospective cohort study. Critical Care. 2013; 17(5):R216 [<a href="/pmc/articles/PMC4057319/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4057319</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24090194" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24090194</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>135.</dt><dd><div class="bk_ref" id="ch11.ref135">Richards
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SH, Winder
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R, Seamark
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D, Seamark
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C, Ewings
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P, Barwick
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A
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et al. Accessing out-of-hours care following implementation of the GMS contract: an observational study. British Journal of General Practice. 2008; 58(550):331–8 [<a href="/pmc/articles/PMC2435660/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2435660</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/18482487" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18482487</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>136.</dt><dd><div class="bk_ref" id="ch11.ref136">Richfield
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E, Adams
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D, Jones
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E, Campbell
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C, Johnson
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M. 28 Specialist palliative care for Parkinson’s disease: experiences of a novel integrative service. Age and Ageing. 2014; 43:(Suppl 1):i7–i7</div></dd></dl><dl class="bkr_refwrap"><dt>137.</dt><dd><div class="bk_ref" id="ch11.ref137">Riolfi
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M, Buja
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A, Zanardo
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C, Marangon
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CF, Manno
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P. Effectiveness of palliative home-care services in reducing hospital admissions and determinants of hospitalization for terminally ill patients followed up by a palliative home-care team: A retrospective cohort study. Palliative Medicine. 2014; 28(5):403–411 [<a href="https://pubmed.ncbi.nlm.nih.gov/24367058" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24367058</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>138.</dt><dd><div class="bk_ref" id="ch11.ref138">Rosenquist
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A, Bergman
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K, Strang
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P. Optimizing hospital-based home care for dying cancer patients: A population-based study. Palliative Medicine. 1999; 13(5):393–7 [<a href="https://pubmed.ncbi.nlm.nih.gov/10659111" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10659111</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>139.</dt><dd><div class="bk_ref" id="ch11.ref139">Rouhollahi
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MR, Saghafinia
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M, Zandehdel
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K, Motlagh
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AG, Kazemian
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A, Mohagheghi
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MA
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et al. Assessment of a hospital palliative care unit (HPCU) for cancer Patients; A conceptual framework. Indian Journal of Palliative Care. 2015; 21(3):317–27 [<a href="/pmc/articles/PMC4617040/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4617040</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26600701" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26600701</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>140.</dt><dd><div class="bk_ref" id="ch11.ref140">Royal College of Physicians. End of Life Care Audit – Dying in Hospital: National report for England 2016. London UK. RCP, 2016. Available from: <a href="https://www.rcplondon.ac.uk/" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.rcplondon.ac.uk/</a></div></dd></dl><dl class="bkr_refwrap"><dt>141.</dt><dd><div class="bk_ref" id="ch11.ref141">Schrijnemaekers
|
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V, Courtens
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A, Kuin
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A, van der Linden
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B, Vernooij-Dassen
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M, van Zuylen
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L
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B, Blankenstein
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N, Deliens
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L, van der Horst
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H. Out-of-hours palliative care provided by GP co-operatives in the Netherlands: A focus group study. European Journal of General Practice. 2011; 17(3):160–6 [<a href="https://pubmed.ncbi.nlm.nih.gov/21574858" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21574858</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>143.</dt><dd><div class="bk_ref" id="ch11.ref143">Schweitzer
|
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B, Blankenstein
|
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N, Slort
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W, Knol
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DL, Deliens
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L, Van Der Horst
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H. Writing information transfers for out-of-hours palliative care: A controlled trial among GPs. Scandinavian Journal of Primary Health Care. 2016; 34(2):186–95 [<a href="/pmc/articles/PMC4977942/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4977942</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/27092979" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27092979</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>144.</dt><dd><div class="bk_ref" id="ch11.ref144">Schweitzer
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BP, Blankenstein
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N, Deliens
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L, van der Horst
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H. Out-of-hours palliative care provided by GP co-operatives: Availability, content and effect of transferred information. BMC Palliative Care. 2009; 8:17 [<a href="/pmc/articles/PMC2789043/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2789043</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19943956" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19943956</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>145.</dt><dd><div class="bk_ref" id="ch11.ref145">Seamark
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D, Blake
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S, Brearley
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S. Dying at home: a qualitative study of family carers’ views of support provided by GPs community staff. British Journal of General Practice. 2014; 64(629):633–634 [<a href="/pmc/articles/PMC4240153/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4240153</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25452545" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25452545</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>146.</dt><dd><div class="bk_ref" id="ch11.ref146">Seow
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H, Brazil
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K, Sussman
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J. Impact of community based, specialist palliative care teams on hospitalisations and emergency department visits late in life and hospital deaths. BMJ. 2014; 348:g3496 [<a href="/pmc/articles/PMC4048125/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4048125</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24906901" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24906901</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>147.</dt><dd><div class="bk_ref" id="ch11.ref147">Shepperd
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S, Doll
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H, Broad
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J, Gladman
|
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J, Iliffe
|
|
S, Langhorne
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P
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S, Goncalves-Bradley
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DC, Straus
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SE, Wee
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B. Hospital at home: home-based end-of-life care. Cochrane Database of Systematic Reviews
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2016, Issue 2. Art. No.: CD009231. DOI: 10.1002/14651858.CD009231.pub2. [<a href="/pmc/articles/PMC7111432/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC7111432</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/26887902" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26887902</span></a>] [<a href="http://dx.crossref.org/10.1002/14651858.CD009231.pub2" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd></dl><dl class="bkr_refwrap"><dt>149.</dt><dd><div class="bk_ref" id="ch11.ref149">Shepperd
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S, Wee
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B, Straus
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SE. Hospital at home: home-based end of life care. Cochrane Database of Systematic Reviews
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M, Bernard
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N, Ishiki
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H, Iwase
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S, Chiba
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T, Fujiwara
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C, Addington-Hall
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S, Briggs
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J, Cox
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C, Addington-Hall
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M, Pearce
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JK, Payne
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SA, Ingleton
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M, Carey
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I, Hanson
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RL, Hayashi
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L, Felner
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K. The medical emergency team call: A sentinel event that triggers goals of care discussion. Critical Care Medicine. 2014; 42(2):322–7 [<a href="https://pubmed.ncbi.nlm.nih.gov/23989179" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23989179</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>159.</dt><dd><div class="bk_ref" id="ch11.ref159">Stewart
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F, Goddard
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M, Franco
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M, Vo
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A, Poon
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P, William
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L. Hospital rapid response team and patients with life-limiting illness: A multicentre retrospective cohort study. Palliative Medicine. 2015; 29(4):302–9 [<a href="https://pubmed.ncbi.nlm.nih.gov/25634630" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25634630</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>161.</dt><dd><div class="bk_ref" id="ch11.ref161">Swetenham
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K, Grantham
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H, Glaetzer
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K. Breaking down the silos: Collaboration delivering an efficient and effective response to palliative care emergencies. Progress in Palliative Care. 2014; 22(4):212–218</div></dd></dl><dl class="bkr_refwrap"><dt>162.</dt><dd><div class="bk_ref" id="ch11.ref162">Takahashi
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PY, Hanson
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GJ, Thorsteinsdottir
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B, Van Houten
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HK, Shah
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ND, Naessens
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B, Salib
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M, Fox-Robichaud
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LH, Delaney
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M, Nelson
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M, Nelson
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M, Noble
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SI, Nelson
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A. What challenges good palliative care provision out-of-hours? A qualitative interview study of out-of-hours general practitioners. BMJ Supportive & Palliative Care. 2011; 1(1):13–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/24653045" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24653045</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>168.</dt><dd><div class="bk_ref" id="ch11.ref168">Taylor
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Jr
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DH, Bull
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J, Zhong
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X, Samsa
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G, Abernethy
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AP. The effect of palliative care on patient functioning. Journal of Palliative Medicine. 2013; 16(10):1227–1231 [<a href="/pmc/articles/PMC3791032/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3791032</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/24020918" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 24020918</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>169.</dt><dd><div class="bk_ref" id="ch11.ref169">Teno
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B, Groot
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M, Engels
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Y, Prins
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J, Verhagen
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A, Milocchi
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F, Tolley
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K, Vaglia
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A, Marcolini
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F, Manfrin
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J, van Selm
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M, Vissers
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K, van Leeuwen
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E, Hasselaar
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F, Finlay
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R, Jong
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BM. The New Millennium Palliative Care Project (2000-2003): the impact of specialised GP advisors. British Journal of General Practice. 2007; 57(539):494–6 [<a href="/pmc/articles/PMC2078186/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2078186</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/17550677" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17550677</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>178.</dt><dd><div class="bk_ref" id="ch11.ref178">van Riet Paap
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J, Engels
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S, Radbruch
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L, Kaasa
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A, Girgis
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A, Girgis
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CHR, Bartels
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UE, Marczynska
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K, Ruppert
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D, Graf
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BM, Hanekop
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GG. Quality of out-of-hospital palliative emergency care depends on the expertise of the emergency medical team-a prospective multi-centre analysis. Supportive Care in Cancer. 2009; 17(12):1499–1506 [<a href="/pmc/articles/PMC3085769/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3085769</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19319576" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19319576</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>185.</dt><dd><div class="bk_ref" id="ch11.ref185">Wilkes
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L, Mohan
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S, White
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K, Smith
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H. Evaluation of an after hours telephone support service for rural palliative care patients and their families: A pilot study. Australian Journal of Rural Health. 2004; 12(3):95–8 [<a href="https://pubmed.ncbi.nlm.nih.gov/15200518" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15200518</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>186.</dt><dd><div class="bk_ref" id="ch11.ref186">Worth
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A, Boyd
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K, Kendall
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M, Heaney
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D, Macleod
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U, Cormie
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P
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et al. Out-of-hours palliative care: A qualitative study of cancer patients, carers and professionals. British Journal of General Practice. 2006; 56(522):6–13 [<a href="/pmc/articles/PMC1821404/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1821404</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/16438809" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16438809</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>187.</dt><dd><div class="bk_ref" id="ch11.ref187">Zimmer
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JG, Groth-Juncker
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A. Off-hour telephone calls to a geriatric home care team. Home Health Care Services Quarterly. 1982; 3(2):63–70 [<a href="https://pubmed.ncbi.nlm.nih.gov/10262331" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10262331</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>188.</dt><dd><div class="bk_ref" id="ch11.ref188">Zimmer
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JG, Groth-Juncker
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A, McCusker
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J. A randomized controlled study of a home health care team. American Journal of Public Health. 1985; 75(2):134–41 [<a href="/pmc/articles/PMC1645992/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1645992</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/3966617" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 3966617</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>189.</dt><dd><div class="bk_ref" id="ch11.ref189">Zimmermann
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C. Effectiveness of specialized palliative care: a systematic review. JAMA. 2008; 299(14):1698–1709 [<a href="https://pubmed.ncbi.nlm.nih.gov/18398082" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 18398082</span></a>]</div></dd></dl></dl></div><div id="appendixesappgroup11"><h2 id="_appendixesappgroup11_">Appendices</h2><div id="ch11.appa"><h3>Appendix A. Review protocols</h3><p id="ch11.appa.tab1"><a href="/books/NBK558771/table/ch11.appa.tab1/?report=objectonly" target="object" rid-ob="figobch11appatab1" class="figpopup">Table 13. Review protocol for what are the best out of hours services, models and policies to support people in their last year of life to stay in their usual place of residence?</a></p><p id="ch11.appa.tab2"><a href="/books/NBK558771/table/ch11.appa.tab2/?report=objectonly" target="object" rid-ob="figobch11appatab2" class="figpopup">Table 14. Health economic review protocol</a></p></div><div id="ch11.appb"><h3>Appendix B. Literature search strategies</h3><p>The literature searches for this review are detailed below and complied with the methodology outlined in Developing NICE guidelines: the manual 2014, updated 2017 <a href="https://www.nice.org.uk/guidance/pmg20/resources/developing-nice-guidelines-the-manual-pdf-72286708700869" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www.nice.org.uk/guidance/pmg20/resources/developing-nice-guidelines-the-manual-pdf-72286708700869</a></p><p><i>For more detailed information, please see the</i>
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<a href="/books/NBK558771/bin/bm1.pdf">Methodology</a>
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<i>Review</i>.</p><div id="ch11.appb.s1"><h4>B.1. Clinical search literature search strategy</h4><p>Searches for were constructed using a PICO framework where population (P) terms were combined with Intervention (I) and in some cases Comparison (C) terms. Outcomes (O) are rarely used in search strategies for interventions as these concepts may not be well described in title, abstract or indexes and therefore difficult to retrieve. Search filters were applied to the search where appropriate.</p><p id="ch11.appb.tab1"><a href="/books/NBK558771/table/ch11.appb.tab1/?report=objectonly" target="object" rid-ob="figobch11appbtab1" class="figpopup">Table 15. Database date parameters and filters used</a></p><p id="ch11.appb.tab2"><a href="/books/NBK558771/table/ch11.appb.tab2/?report=objectonly" target="object" rid-ob="figobch11appbtab2" class="figpopup">Medline (Ovid) search terms</a></p><p id="ch11.appb.tab3"><a href="/books/NBK558771/table/ch11.appb.tab3/?report=objectonly" target="object" rid-ob="figobch11appbtab3" class="figpopup">Embase (Ovid) search terms</a></p><p id="ch11.appb.tab4"><a href="/books/NBK558771/table/ch11.appb.tab4/?report=objectonly" target="object" rid-ob="figobch11appbtab4" class="figpopup">Cochrane Library (Wiley) search terms</a></p><p id="ch11.appb.tab5"><a href="/books/NBK558771/table/ch11.appb.tab5/?report=objectonly" target="object" rid-ob="figobch11appbtab5" class="figpopup">CINAHL (EBSCO) search terms</a></p><p id="ch11.appb.tab6"><a href="/books/NBK558771/table/ch11.appb.tab6/?report=objectonly" target="object" rid-ob="figobch11appbtab6" class="figpopup">PsycINFO (ProQuest) search terms</a></p><p id="ch11.appb.tab7"><a href="/books/NBK558771/table/ch11.appb.tab7/?report=objectonly" target="object" rid-ob="figobch11appbtab7" class="figpopup">HMIC (Ovid) search terms</a></p><p id="ch11.appb.tab8"><a href="/books/NBK558771/table/ch11.appb.tab8/?report=objectonly" target="object" rid-ob="figobch11appbtab8" class="figpopup">SPP (Ovid) search terms</a></p><p id="ch11.appb.tab9"><a href="/books/NBK558771/table/ch11.appb.tab9/?report=objectonly" target="object" rid-ob="figobch11appbtab9" class="figpopup">ASSIA (ProQuest) search terms</a></p></div><div id="ch11.appb.s2"><h4>B.2. Health Economics literature search strategy</h4><p>Health economic evidence was identified by conducting a broad search relating to end of life care in NHS Economic Evaluation Database (NHS EED – this ceased to be updated after March 2015) and the Health Technology Assessment database (HTA) with no date restrictions. NHS EED and HTA databases are hosted by the Centre for Research and Dissemination (CRD). Additional searches were run on Medline and Embase for health economics, economic modelling and quality of life studies.</p><p id="ch11.appb.tab10"><a href="/books/NBK558771/table/ch11.appb.tab10/?report=objectonly" target="object" rid-ob="figobch11appbtab10" class="figpopup">Table 16. Database date parameters and filters used</a></p><p id="ch11.appb.tab11"><a href="/books/NBK558771/table/ch11.appb.tab11/?report=objectonly" target="object" rid-ob="figobch11appbtab11" class="figpopup">Medline (Ovid) search terms</a></p><p id="ch11.appb.tab12"><a href="/books/NBK558771/table/ch11.appb.tab12/?report=objectonly" target="object" rid-ob="figobch11appbtab12" class="figpopup">Embase (Ovid) search terms</a></p><p id="ch11.appb.tab13"><a href="/books/NBK558771/table/ch11.appb.tab13/?report=objectonly" target="object" rid-ob="figobch11appbtab13" class="figpopup">NHS EED and HTA (CRD) search terms</a></p></div></div><div id="ch11.appc"><h3>Appendix C. Clinical evidence selection</h3><p id="ch11.appc.fig1"><a href="/books/NBK558771/figure/ch11.appc.fig1/?report=objectonly" target="object" rid-ob="figobch11appcfig1" class="figpopup">Figure 1. Flow chart of clinical study selection for the review of out of hours services</a></p></div><div id="ch11.appd"><h3>Appendix D. Clinical evidence tables</h3><p id="ch11.appd.et1"><a href="/books/NBK558771/bin/ch11-appd-et1.pdf" class="bk_dwnld_icn bk_dwnld_pdf">Download PDF</a><span class="small"> (263K)</span></p></div><div id="ch11.appe"><h3>Appendix E. Forest plots</h3><div id="ch11.appe.s1"><h4>E.1. Out of hours service (Rapid response service available) versus usual care (Rapid response service not available) in adults with progressive life-limiting conditions thought to be entering their last year of life (Gage 2015 – Holdsworth 2015)</h4><p id="ch11.appe.fig1"><a href="/books/NBK558771/figure/ch11.appe.fig1/?report=objectonly" target="object" rid-ob="figobch11appefig1" class="figpopup">Figure 2. Carers quality of life (EQ5D, 0-1) (8 months)</a></p><p id="ch11.appe.fig2"><a href="/books/NBK558771/figure/ch11.appe.fig2/?report=objectonly" target="object" rid-ob="figobch11appefig2" class="figpopup">Figure 3. Carers quality of life (SF12 Physical Component Summary Score, 0-100) (8 months)</a></p><p id="ch11.appe.fig3"><a href="/books/NBK558771/figure/ch11.appe.fig3/?report=objectonly" target="object" rid-ob="figobch11appefig3" class="figpopup">Figure 4. Carers quality of life (SF12 Mental Component Summary Score, 0-100) (8 months)</a></p><p id="ch11.appe.fig4"><a href="/books/NBK558771/figure/ch11.appe.fig4/?report=objectonly" target="object" rid-ob="figobch11appefig4" class="figpopup">Figure 5. Preferred and actual place of death (N achieving (initial) place of death)</a></p><p id="ch11.appe.fig5"><a href="/books/NBK558771/figure/ch11.appe.fig5/?report=objectonly" target="object" rid-ob="figobch11appefig5" class="figpopup">Figure 6. Preferred and actual place of death (N achieving (final) place of death)</a></p></div><div id="ch11.appe.s2"><h4>E.2. Out of hours service (Rapid response service users) versus usual care (Rapid response service non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life (Gage 2015 – Holdsworth 2015)</h4><p id="ch11.appe.fig6"><a href="/books/NBK558771/figure/ch11.appe.fig6/?report=objectonly" target="object" rid-ob="figobch11appefig6" class="figpopup">Figure 7. Preferred and actual place of death (N achieving (initial) place of death)</a></p><p id="ch11.appe.fig7"><a href="/books/NBK558771/figure/ch11.appe.fig7/?report=objectonly" target="object" rid-ob="figobch11appefig7" class="figpopup">Figure 8. Number of visits to accident and emergency (N with ≥ 1 contact with acute care)</a></p><p id="ch11.appe.fig8"><a href="/books/NBK558771/figure/ch11.appe.fig8/?report=objectonly" target="object" rid-ob="figobch11appefig8" class="figpopup">Figure 9. Use of community services (N with ≥ 1 contact with GP/primary care)</a></p><p id="ch11.appe.fig9"><a href="/books/NBK558771/figure/ch11.appe.fig9/?report=objectonly" target="object" rid-ob="figobch11appefig9" class="figpopup">Figure 10. Use of community services (N with ≥ 1 contact with community care)</a></p><p id="ch11.appe.fig10"><a href="/books/NBK558771/figure/ch11.appe.fig10/?report=objectonly" target="object" rid-ob="figobch11appefig10" class="figpopup">Figure 11. Use of community services (N with ≥ 1 contact with Marie Curie visits)</a></p><p id="ch11.appe.fig11"><a href="/books/NBK558771/figure/ch11.appe.fig11/?report=objectonly" target="object" rid-ob="figobch11appefig11" class="figpopup">Figure 12. Use of community services (N with ≥ 1 contact with out of hours services)</a></p><p id="ch11.appe.fig12"><a href="/books/NBK558771/figure/ch11.appe.fig12/?report=objectonly" target="object" rid-ob="figobch11appefig12" class="figpopup">Figure 13. Use of community services (N with ≥ 1 contact with hospice, excluding rapid response service)</a></p><p id="ch11.appe.fig13"><a href="/books/NBK558771/figure/ch11.appe.fig13/?report=objectonly" target="object" rid-ob="figobch11appefig13" class="figpopup">Figure 14. Use of community services (N receiving ≥ 1 social service)</a></p></div><div id="ch11.appe.s3"><h4>E.3. Out of hours services (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme with out of hours non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life (Purdy 2015)</h4><p id="ch11.appe.fig14"><a href="/books/NBK558771/figure/ch11.appe.fig14/?report=objectonly" target="object" rid-ob="figobch11appefig14" class="figpopup">Figure 15. Preferred and actual place of death (Place of death – acute hospital)</a></p><p id="ch11.appe.fig15"><a href="/books/NBK558771/figure/ch11.appe.fig15/?report=objectonly" target="object" rid-ob="figobch11appefig15" class="figpopup">Figure 16. Preferred and actual place of death (Place of death – community hospital)</a></p><p id="ch11.appe.fig16"><a href="/books/NBK558771/figure/ch11.appe.fig16/?report=objectonly" target="object" rid-ob="figobch11appefig16" class="figpopup">Figure 17. Preferred and actual place of death (Place of death – home)</a></p><p id="ch11.appe.fig17"><a href="/books/NBK558771/figure/ch11.appe.fig17/?report=objectonly" target="object" rid-ob="figobch11appefig17" class="figpopup">Figure 18. Preferred and actual place of death (Place of death – care home)</a></p><p id="ch11.appe.fig18"><a href="/books/NBK558771/figure/ch11.appe.fig18/?report=objectonly" target="object" rid-ob="figobch11appefig18" class="figpopup">Figure 19. Preferred and actual place of death (Place of death – hospice)</a></p><p id="ch11.appe.fig19"><a href="/books/NBK558771/figure/ch11.appe.fig19/?report=objectonly" target="object" rid-ob="figobch11appefig19" class="figpopup">Figure 20. Preferred and actual place of death (Place of death – elsewhere)</a></p><p id="ch11.appe.fig20"><a href="/books/NBK558771/figure/ch11.appe.fig20/?report=objectonly" target="object" rid-ob="figobch11appefig20" class="figpopup">Figure 21. Number of hospital visits (patients with one or more emergency admissions < 30 days)</a></p><p id="ch11.appe.fig21"><a href="/books/NBK558771/figure/ch11.appe.fig21/?report=objectonly" target="object" rid-ob="figobch11appefig21" class="figpopup">Figure 22. Number of hospital visits (patients with one or more emergency admissions < 7 days)</a></p><p id="ch11.appe.fig22"><a href="/books/NBK558771/figure/ch11.appe.fig22/?report=objectonly" target="object" rid-ob="figobch11appefig22" class="figpopup">Figure 23. Number of hospital visits (mean emergency admission per patient < 30 days)</a></p><p id="ch11.appe.fig23"><a href="/books/NBK558771/figure/ch11.appe.fig23/?report=objectonly" target="object" rid-ob="figobch11appefig23" class="figpopup">Figure 24. Number of hospital visits (mean emergency admission per patient < 7 days)</a></p><p id="ch11.appe.fig24"><a href="/books/NBK558771/figure/ch11.appe.fig24/?report=objectonly" target="object" rid-ob="figobch11appefig24" class="figpopup">Figure 25. Number of visits to accident and emergency (patients with one or more ED attendance < 30 days)</a></p><p id="ch11.appe.fig25"><a href="/books/NBK558771/figure/ch11.appe.fig25/?report=objectonly" target="object" rid-ob="figobch11appefig25" class="figpopup">Figure 26. Number of visits to accident and emergency (patients with one or more ED attendance < 7 days)</a></p><p id="ch11.appe.fig26"><a href="/books/NBK558771/figure/ch11.appe.fig26/?report=objectonly" target="object" rid-ob="figobch11appefig26" class="figpopup">Figure 27. Number of visits to accident and emergency (mean ED attendance per patient < 30 days)</a></p><p id="ch11.appe.fig27"><a href="/books/NBK558771/figure/ch11.appe.fig27/?report=objectonly" target="object" rid-ob="figobch11appefig27" class="figpopup">Figure 28. Number of visits to accident and emergency (mean ED attendance per patient < 7 days)</a></p></div><div id="ch11.appe.s4"><h4>E.4. Out of hours services (Delivering Choice Programme with out of hours users) versus other services (Delivering Choice Programme without out of hours users) in adults with progressive life-limiting conditions thought to be entering their last year of life (Purdy 2015)</h4><p id="ch11.appe.fig28"><a href="/books/NBK558771/figure/ch11.appe.fig28/?report=objectonly" target="object" rid-ob="figobch11appefig28" class="figpopup">Figure 29. Preferred and actual place of death (Place of death – acute hospital)</a></p><p id="ch11.appe.fig29"><a href="/books/NBK558771/figure/ch11.appe.fig29/?report=objectonly" target="object" rid-ob="figobch11appefig29" class="figpopup">Figure 30. Preferred and actual place of death (Place of death – home)</a></p><p id="ch11.appe.fig30"><a href="/books/NBK558771/figure/ch11.appe.fig30/?report=objectonly" target="object" rid-ob="figobch11appefig30" class="figpopup">Figure 31. Preferred and actual place of death (Place of death – care home)</a></p><p id="ch11.appe.fig31"><a href="/books/NBK558771/figure/ch11.appe.fig31/?report=objectonly" target="object" rid-ob="figobch11appefig31" class="figpopup">Figure 32. Preferred and actual place of death (Place of death – hospice)</a></p><p id="ch11.appe.fig32"><a href="/books/NBK558771/figure/ch11.appe.fig32/?report=objectonly" target="object" rid-ob="figobch11appefig32" class="figpopup">Figure 33. Preferred and actual place of death (Place of death – elsewhere)</a></p><p id="ch11.appe.fig33"><a href="/books/NBK558771/figure/ch11.appe.fig33/?report=objectonly" target="object" rid-ob="figobch11appefig33" class="figpopup">Figure 34. Number of hospital visits (patients with one or more emergency admissions <30 days)</a></p><p id="ch11.appe.fig34"><a href="/books/NBK558771/figure/ch11.appe.fig34/?report=objectonly" target="object" rid-ob="figobch11appefig34" class="figpopup">Figure 35. Number of hospital visits (patients with one or more emergency admissions <7 days)</a></p><p id="ch11.appe.fig35"><a href="/books/NBK558771/figure/ch11.appe.fig35/?report=objectonly" target="object" rid-ob="figobch11appefig35" class="figpopup">Figure 36. Number of hospital visits (mean emergency admissions per patient <30 days)</a></p><p id="ch11.appe.fig36"><a href="/books/NBK558771/figure/ch11.appe.fig36/?report=objectonly" target="object" rid-ob="figobch11appefig36" class="figpopup">Figure 37. Number of hospital visits (mean emergency admissions per patient <7 days)</a></p><p id="ch11.appe.fig37"><a href="/books/NBK558771/figure/ch11.appe.fig37/?report=objectonly" target="object" rid-ob="figobch11appefig37" class="figpopup">Figure 38. Number of visits to accident and emergency (patients with one or more ED attendance <30days)</a></p><p id="ch11.appe.fig38"><a href="/books/NBK558771/figure/ch11.appe.fig38/?report=objectonly" target="object" rid-ob="figobch11appefig38" class="figpopup">Figure 39. Number of visits to accident and emergency (patients with one or more ED attendance <7days)</a></p><p id="ch11.appe.fig39"><a href="/books/NBK558771/figure/ch11.appe.fig39/?report=objectonly" target="object" rid-ob="figobch11appefig39" class="figpopup">Figure 40. Number of visits to accident and emergency (mean ED attendance per patient <30 days)</a></p><p id="ch11.appe.fig40"><a href="/books/NBK558771/figure/ch11.appe.fig40/?report=objectonly" target="object" rid-ob="figobch11appefig40" class="figpopup">Figure 41. Number of visits to accident and emergency (mean ED attendance per patient <7 days)</a></p></div><div id="ch11.appe.s5"><h4>E.5. Out of hours service (Palliative home care) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life (Riolfi 2014)</h4><p id="ch11.appe.fig41"><a href="/books/NBK558771/figure/ch11.appe.fig41/?report=objectonly" target="object" rid-ob="figobch11appefig41" class="figpopup">Figure 42. Preferred and actual place of death (Place of death - hospital)</a></p><p id="ch11.appe.fig42"><a href="/books/NBK558771/figure/ch11.appe.fig42/?report=objectonly" target="object" rid-ob="figobch11appefig42" class="figpopup">Figure 43. Preferred and actual place of death (Place of death – country hospital)</a></p><p id="ch11.appe.fig43"><a href="/books/NBK558771/figure/ch11.appe.fig43/?report=objectonly" target="object" rid-ob="figobch11appefig43" class="figpopup">Figure 44. Preferred and actual place of death (Place of death – home)</a></p><p id="ch11.appe.fig44"><a href="/books/NBK558771/figure/ch11.appe.fig44/?report=objectonly" target="object" rid-ob="figobch11appefig44" class="figpopup">Figure 45. Preferred and actual place of death (Place of death – nursing home)</a></p><p id="ch11.appe.fig45"><a href="/books/NBK558771/figure/ch11.appe.fig45/?report=objectonly" target="object" rid-ob="figobch11appefig45" class="figpopup">Figure 46. Hospitalisation (number of hospitalisations in the last 2 months of life)</a></p><p id="ch11.appe.fig46"><a href="/books/NBK558771/figure/ch11.appe.fig46/?report=objectonly" target="object" rid-ob="figobch11appefig46" class="figpopup">Figure 47. Length of stay (time spent in hospital in the last 2 months of life)</a></p></div><div id="ch11.appe.s6"><h4>E.6. Out of hours services (Specialist palliative care team) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life (Seow 2014)</h4><p id="ch11.appe.fig47"><a href="/books/NBK558771/figure/ch11.appe.fig47/?report=objectonly" target="object" rid-ob="figobch11appefig47" class="figpopup">Figure 48. Preferred and actual place of death (Place of death - hospital)</a></p><p id="ch11.appe.fig48"><a href="/books/NBK558771/figure/ch11.appe.fig48/?report=objectonly" target="object" rid-ob="figobch11appefig48" class="figpopup">Figure 49. Hospitalisation (last 2 weeks of life)</a></p><p id="ch11.appe.fig49"><a href="/books/NBK558771/figure/ch11.appe.fig49/?report=objectonly" target="object" rid-ob="figobch11appefig49" class="figpopup">Figure 50. Number of visits to accident and emergency (last two weeks of life)</a></p></div></div><div id="ch11.appf"><h3>Appendix F. GRADE tables</h3><p id="ch11.appf.tab1"><a href="/books/NBK558771/table/ch11.appf.tab1/?report=objectonly" target="object" rid-ob="figobch11appftab1" class="figpopup">Table 17. Clinical evidence profile: out of hours service (Rapid response service available) versus usual care (Rapid response service not available, Rapid response service not available) in adults with progressive life-limiting conditions thought to be entering their last year of life</a></p><p id="ch11.appf.tab2"><a href="/books/NBK558771/table/ch11.appf.tab2/?report=objectonly" target="object" rid-ob="figobch11appftab2" class="figpopup">Table 18. Clinical evidence profile: out of hours service (Rapid response service users) versus usual care (Rapid response service not available, Rapid response service non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</a></p><p id="ch11.appf.tab3"><a href="/books/NBK558771/table/ch11.appf.tab3/?report=objectonly" target="object" rid-ob="figobch11appftab3" class="figpopup">Table 19. Clinical evidence profile: out of hours service (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme with out of hours non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</a></p><p id="ch11.appf.tab4"><a href="/books/NBK558771/table/ch11.appf.tab4/?report=objectonly" target="object" rid-ob="figobch11appftab4" class="figpopup">Table 20. Clinical evidence profile: out of hours service (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme without out of hours non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</a></p><p id="ch11.appf.tab5"><a href="/books/NBK558771/table/ch11.appf.tab5/?report=objectonly" target="object" rid-ob="figobch11appftab5" class="figpopup">Table 21. Clinical evidence profile: out of hours service (Palliative home care service) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life</a></p><p id="ch11.appf.tab6"><a href="/books/NBK558771/table/ch11.appf.tab6/?report=objectonly" target="object" rid-ob="figobch11appftab6" class="figpopup">Table 22. Clinical evidence profile: out of hours service (Specialist palliative care team) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life</a></p></div><div id="ch11.appg"><h3>Appendix G. Health economic evidence selection</h3><p id="ch11.appg.fig1"><a href="/books/NBK558771/figure/ch11.appg.fig1/?report=objectonly" target="object" rid-ob="figobch11appgfig1" class="figpopup">Figure 51. Flow chart of health economic study selection for the guideline</a></p></div><div id="ch11.apph"><h3>Appendix H. Health economic analysis</h3><p>A cost analysis was conducted for different out-of-hours community interventions identified by the committee, from the literature or from the call for evidence (please see the details of the analysis in Appendix 1 of the guideline via the NICE website).</p></div><div id="ch11.appi"><h3>Appendix I. Excluded studies</h3><div id="ch11.appi.s1"><h4>I.1. Excluded clinical studies</h4><p id="ch11.appi.tab1"><a href="/books/NBK558771/table/ch11.appi.tab1/?report=objectonly" target="object" rid-ob="figobch11appitab1" class="figpopup">Table 23. Studies excluded from the clinical review</a></p></div><div id="ch11.appi.s2"><h4>I.2. Excluded health economic studies</h4><p id="ch11.appi.tab2"><a href="/books/NBK558771/table/ch11.appi.tab2/?report=objectonly" target="object" rid-ob="figobch11appitab2" class="figpopup">Table 24. Studies excluded from the health economic review</a></p></div></div></div></div><div class="fm-sec"><div><p>Final</p></div><div><p>Evidence review</p><p>Developed by the National Guideline Centre, hosted by the Royal College of Physicians</p></div><div><p><b>Disclaimer</b>: The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals are expected to take this guideline fully into account, alongside the individual needs, preferences and values of their patients or service users. The recommendations in this guideline are not mandatory and the guideline does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian.</p><p>Local commissioners and/or providers have a responsibility to enable the guideline to be applied when individual health professionals and their patients or service users wish to use it. They should do so in the context of local and national priorities for funding and developing services, and in light of their duties to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with compliance with those duties.</p><p>NICE guidelines cover health and care in England. Decisions on how they apply in other UK countries are made by ministers in the <a href="http://wales.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Welsh Government</a>, <a href="http://www.scotland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Scottish Government</a>, and <a href="http://www.northernireland.gov.uk/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Northern Ireland Executive</a>. All NICE guidance is subject to regular review and may be updated or withdrawn.</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> © NICE 2019.</div><div class="small"><span class="label">Bookshelf ID: NBK558771</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32614556" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">32614556</a></span></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article><article data-type="table-wrap" id="figobch11tab1"><div id="ch11.tab1" class="table"><h3><span class="label">Table 1</span><span class="title">PICO characteristics of review question</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab1_lrgtbl__"><table><tbody><tr><th id="hd_b_ch11.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><td headers="hd_b_ch11.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adults (aged 18 years or over) with progressive life-limiting conditions thought to be entering their last year of life</td></tr><tr><th id="hd_b_ch11.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intervention</th><td headers="hd_b_ch11.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Out of hours service</td></tr><tr><th id="hd_b_ch11.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Comparisons</th><td headers="hd_b_ch11.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Out of hours service</p>
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<p>Other service (not out of hours)</p>
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<p>Usual care</p>
|
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</td></tr><tr><th id="hd_b_ch11.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes</th><td headers="hd_b_ch11.tab1_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>CRITICAL
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<dl id="ch11.l1" class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt1"><p class="no_top_margin">Quality of life (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt2"><p class="no_top_margin">Preferred and actual place of death (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt3"><p class="no_top_margin">Preferred and actual place of care (Dichotomous)</p></dd></dl></dl></p>
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<p>IMPORTANT
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<dl id="ch11.l2" class="temp-labeled-list"><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt4"><p class="no_top_margin">Length of survival (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt5"><p class="no_top_margin">Length of stay (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt6"><p class="no_top_margin">Hospitalisation (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt7"><p class="no_top_margin">Number of hospital visits (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt8"><p class="no_top_margin">Number of visits to accident and emergency (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt9"><p class="no_top_margin">Number of unscheduled admissions (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt10"><p class="no_top_margin">Use of community services (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt11"><p class="no_top_margin">Staff satisfaction (Continuous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt12"><p class="no_top_margin">Avoidable/inappropriate admissions to ICU (Dichotomous)</p></dd></dl><dl class="bkr_refwrap"><dt>-</dt><dd id="ch11.lt13"><p class="no_top_margin">Inappropriate attempts at cardiopulmonary resuscitation (Dichotomous)</p></dd></dl></dl></p></td></tr><tr><th id="hd_b_ch11.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study design</th><td headers="hd_b_ch11.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Systematic Review</p>
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<p>RCT</p>
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<p>Non-randomised comparative study, including before and after studies and interrupted-time-series.</p>
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</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11tab2"><div id="ch11.tab2" class="table"><h3><span class="label">Table 2</span><span class="title">Summary of clinical studies included in the evidence review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab2_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_ch11.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Intervention and comparison</th><th id="hd_h_ch11.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Population</th><th id="hd_h_ch11.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes</th><th id="hd_h_ch11.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Comments</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gage 2015<a class="bibr" href="#ch11.ref57" rid="ch11.ref57"><sup>57</sup></a> (Holdsworth 2015<a class="bibr" href="#ch11.ref77" rid="ch11.ref77"><sup>77</sup></a>)</td><td headers="hd_h_ch11.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Rapid response service users.</p>
|
|
<p>Rapid response service non-users.</p>
|
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<p>Rapid response service available.</p>
|
|
<p>Rapid response service not available.</p>
|
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<p>The rapid response service was delivered by health care assistants and supported by a multiprofessional team. The team had access to a service coordinator</p>
|
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</td><td headers="hd_h_ch11.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Patients newly referred to the hospice services</p>
|
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<p>N=164</p>
|
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<p>UK</p>
|
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</td><td headers="hd_h_ch11.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Preferred and actual place of death;</p>
|
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<p>Use of community services;</p>
|
|
<p>GP contacts;</p>
|
|
<p>All community contacts;</p>
|
|
<p>All Marie Curie visits;</p>
|
|
<p>All out of hours contacts:</p>
|
|
<p>Hospice contacts;</p>
|
|
<p>Social services;</p>
|
|
<p>Number of visits to accident and emergency;</p>
|
|
<p>Carers’ quality of life (SF-12, EQ5D)</p>
|
|
</td><td headers="hd_h_ch11.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>No description of usual care.</p>
|
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<p>Only 36% of people in the ‘RRS available’ group actually accessed the service</p>
|
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</td></tr><tr><td headers="hd_h_ch11.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Purdy 2015<a class="bibr" href="#ch11.ref133" rid="ch11.ref133"><sup>133</sup></a></td><td headers="hd_h_ch11.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Marie Curie Cancer Care Delivering Choice Programme (with out of hours service) users.</p>
|
|
<p>Marie Curie Cancer Care Delivering Choice Programme (without out of hours service).</p>
|
|
<p>Marie Curie Cancer Care Delivering Choice Programme (with out of hours service) non-users</p>
|
|
<p>Intervention consisted of:</p>
|
|
<p>Out of hours advice and response lines manned by specialist nurses from 5pm to 1pm weekends and bank holidays.</p>
|
|
<p>Two front of house hospital-based discharge nurses.</p>
|
|
<p>Two end of life care coordinators.</p>
|
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<p>These services were supported by an electronic end of life care register to record advance care wishes</p>
|
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</td><td headers="hd_h_ch11.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Patients who died between Sep 2011-Feb 2012, who were expected to die and potentially eligible for end-of-life care</p>
|
|
<p>N=2785</p>
|
|
<p>UK</p>
|
|
</td><td headers="hd_h_ch11.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Place of death:</p>
|
|
<p>Acute hospital;</p>
|
|
<p>Home;</p>
|
|
<p>Care home (not usual place of residence);</p>
|
|
<p>Hospice;</p>
|
|
<p>Community hospital;</p>
|
|
<p>Elsewhere;</p>
|
|
<p>Number of hospital visits;</p>
|
|
<p>Patients with one or more emergency admissions (< 30 days, < 7 days);</p>
|
|
<p>Mean emergency admissions per patient (< 30 days, < 7 days);</p>
|
|
<p>Number of visits to accident and emergency;</p>
|
|
<p>Patients with one or more ED attendance (< 30 days, < 7 days);</p>
|
|
<p>Mean ED attendance per patient (< 30 days, < 7 days)</p>
|
|
</td><td headers="hd_h_ch11.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>23% used the Delivery Choice intervention</p>
|
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<p>Out of hours advice line 9%.</p>
|
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<p>Preferred place of death not reported</p>
|
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</td></tr><tr><td headers="hd_h_ch11.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Riolfi 2014<a class="bibr" href="#ch11.ref137" rid="ch11.ref137"><sup>137</sup></a></td><td headers="hd_h_ch11.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Palliative home care service.</p>
|
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<p>Usual care (palliative home care service not available).</p>
|
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<p>The service consisted of two palliative care physicians and 30 specialist nurses who cooperate with GPs.</p>
|
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<p>The services of a palliative care physician or nurse are assured from Monday to Friday (8am to 8pm). On Saturdays and Sundays there is a nurse on call 8am to 8pm. During the night and weekends patients and caregivers and colleagues can always contact a palliative care physician by phone</p>
|
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</td><td headers="hd_h_ch11.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>People with predicted life expectancy of three months</p>
|
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<p>N=402</p>
|
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<p>Italy</p>
|
|
</td><td headers="hd_h_ch11.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Place of death:</p>
|
|
<p>Home;</p>
|
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<p>Hospital;</p>
|
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<p>Nursing home;</p>
|
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<p>Country hospital;</p>
|
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<p>Length of stay (time spent in hospital in the last 2 months of life);</p>
|
|
<p>Hospitalisation (number of hospitalisations in the last 2 months of life)</p>
|
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</td><td headers="hd_h_ch11.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Seow 2014<a class="bibr" href="#ch11.ref146" rid="ch11.ref146"><sup>146</sup></a></td><td headers="hd_h_ch11.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Specialist palliative care team N=3109.</p>
|
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<p>Usual care.</p>
|
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<p>Core members: nurses, palliative care physicians, and family physicians. The team provided interdisciplinary, home-based palliative care to people with palliative care needs. Core features of services were 24/7 care and collaboration between health professionals</p>
|
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</td><td headers="hd_h_ch11.tab2_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Patients receiving care from specialist care teams who:</p>
|
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<p>a) provide interdisciplinary, home based palliative care; b) were the only team in their respective region; c) had little or no change in staffing between 2009 until 2012; d) had broad admission criteria that is, not limited to one disease; e) admitted more than 50 patients; f) were available to patients 24/7</p>
|
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<p>N=9327</p>
|
|
<p>Canada</p>
|
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</td><td headers="hd_h_ch11.tab2_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Hospitalisation (number of people in hospital in last 2 weeks of life);</p>
|
|
<p>Number of visits to accident and emergency (ED visits in the last 2 weeks of life);</p>
|
|
<p>Place of death</p>
|
|
<p>(hospital)</p>
|
|
</td><td headers="hd_h_ch11.tab2_1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">All people in the intervention group received care from specialist palliative care team</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11tab3"><div id="ch11.tab3" class="table"><h3><span class="label">Table 3</span><span class="title">Proportion of participants using out of hours services</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab3_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_ch11.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number for each intervention</th><th id="hd_h_ch11.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Proportion using out of hours service</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Purdy 2015<a class="bibr" href="#ch11.ref133" rid="ch11.ref133"><sup>133</sup></a></td><td headers="hd_h_ch11.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>All users were offered the intervention</p>
|
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<p>Users of intervention N=819 (N=616 with out of hours; N=213 without out of hours)</p>
|
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<p>Nonusers N=2765 (N=1956 with out of hours, N=809 without out of hours)</p>
|
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</td><td headers="hd_h_ch11.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>23% used the Delivery Choice intervention</p>
|
|
<p>Out of hours advice line 9%</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Riolfi 2014<a class="bibr" href="#ch11.ref137" rid="ch11.ref137"><sup>137</sup></a></td><td headers="hd_h_ch11.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Not all patients offered the intervention</p>
|
|
<p>Offered palliative care N=160</p>
|
|
<p>Not given palliative care N=242</p>
|
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</td><td headers="hd_h_ch11.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study states that all of the patients were eligible for palliative care (they all died of cancer within two months) – our analysis compared patients who did or did not join the palliative care program</td></tr><tr><td headers="hd_h_ch11.tab3_1_1_1_1" rowspan="2" colspan="1" style="text-align:left;vertical-align:top;">Gage 2015<a class="bibr" href="#ch11.ref57" rid="ch11.ref57"><sup>57</sup></a> (Holdsworth 2015<a class="bibr" href="#ch11.ref77" rid="ch11.ref77"><sup>77</sup></a>)</td><td headers="hd_h_ch11.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>Comparison 1: Service was available to all patients</p>
|
|
<p>Rapid response service (RRS) users N= 247</p>
|
|
<p>RRS non-users N=441</p>
|
|
</td><td headers="hd_h_ch11.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Service was available to all people accessing hospice services in the area</td></tr><tr><td headers="hd_h_ch11.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Comparison 2: Service was available only to intervention group</p>
|
|
<p>RRS available N=688 (and carers, N=48)</p>
|
|
<p>RRS not available N=265 (and carers, N=16)</p>
|
|
</td><td headers="hd_h_ch11.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Only 36% of people in the ‘RRS available’ group actually accessed the service</td></tr><tr><td headers="hd_h_ch11.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Seow 2014<a class="bibr" href="#ch11.ref146" rid="ch11.ref146"><sup>146</sup></a></td><td headers="hd_h_ch11.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>People who received care from specialist palliative care team (‘exposed’) N=3109</p>
|
|
<p>People who received usual care (‘unexposed’) N=3109</p>
|
|
</td><td headers="hd_h_ch11.tab3_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">All people in the intervention group received care from specialist palliative care team</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11tab4"><div id="ch11.tab4" class="table"><h3><span class="label">Table 4</span><span class="title">Clinical evidence summary: out of hours service (Rapid response service available) versus usual care (Rapid response service not available) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab4_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.tab4_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_ch11.tab4_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_ch11.tab4_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_ch11.tab4_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_ch11.tab4_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_ch11.tab4_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_ch11.tab4_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.tab4_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_ch11.tab4_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_ch11.tab4_1_1_1_5" id="hd_h_ch11.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Usual care (RRS not available)</th><th headers="hd_h_ch11.tab4_1_1_1_5" id="hd_h_ch11.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Rapid Response Service available (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Carers quality of life (EQ5D, 0-1) 8 months</td><td headers="hd_h_ch11.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>64</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">-</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean carers quality of life (EQ5D) 8 months - rapid response service available versus rapid response service not available in the control groups was 0.77</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean carers quality of life (EQ5D) 8 months - rapid response service available versus rapid response service not availablein the intervention groups was 0.05 lower (0.12 lower to 0.02 higher)</td></tr><tr><td headers="hd_h_ch11.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Carers quality of life (SF12 Physical Component Summary Score, 0-100) 8 months</td><td headers="hd_h_ch11.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>64</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">-</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean carers quality of life (SF12 physical) 8 months - rapid response service available versus rapid response service not available in the control groups was 44.27</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean carers quality of life (SF12 physical) 8 months - rapid response service available versus rapid response service not available in the intervention groups was 1.86 higher (0.99 lower to 4.71 higher)</td></tr><tr><td headers="hd_h_ch11.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Carers quality of life (SF12 Mental Component Summary Score, 0-100) 8 months</td><td headers="hd_h_ch11.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>64</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">-</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean carers quality of life (SF12 mental) 8 months - rapid response service available versus rapid response service not available in the control groups was 46.47</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean carers quality of life (SF12 mental) 8 months - rapid response service available versus rapid response service not available in the intervention groups was 4.93 lower (8 to 1.86 lower)</td></tr><tr><td headers="hd_h_ch11.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Achieved (initial) place of death)</td><td headers="hd_h_ch11.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>953</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.01 (0.9 to 1.13)</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">619 per 1000</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>6 more per 1000</p>
|
|
<p>(from 62 fewer to 80 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Achieved (final) place of death)</td><td headers="hd_h_ch11.tab4_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>953</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab4_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.95 (0.86 to 1.04)</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">698 per 1000</td><td headers="hd_h_ch11.tab4_1_1_1_5 hd_h_ch11.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>35 fewer per 1000</p>
|
|
<p>(from 98 fewer to 28 more)</p>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.tab4_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.tab4_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11tab5"><div id="ch11.tab5" class="table"><h3><span class="label">Table 5</span><span class="title">Clinical evidence summary: out of hours service (Rapid response service users) versus usual care (Rapid response service non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab5/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab5_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.tab5_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_ch11.tab5_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_ch11.tab5_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_ch11.tab5_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_ch11.tab5_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_ch11.tab5_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_ch11.tab5_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.tab5_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_ch11.tab5_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_ch11.tab5_1_1_1_5" id="hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Usual care (RRS non-users)</th><th headers="hd_h_ch11.tab5_1_1_1_5" id="hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Rapid Response Service users (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Achieved (initial) place of death)</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>681</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.17 (1.04 to 1.31)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">592 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>101 more per 1000</p>
|
|
<p>(from 24 more to more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (Number with >1 contact with acute care)</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>688</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup> due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.92 (0.8 to 1.07)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">565 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>45 fewer per 1000</p>
|
|
<p>(from 113 fewer to more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Use of community services (Number with >1 contact with GP/primary care)</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>426</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.22 (1.11 to 1.34)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">719 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>158 more per 1000</p>
|
|
<p>(from 79 more to more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Use of community services (Number with>1 contact with community care)</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>688</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.3 (1.21 to 1.4)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">694 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>208 more per 1000</p>
|
|
<p>(from 146 more to 278 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Use of community services (Number with >1 contact with Marie Curie visits</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>688</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 9.82 (4.17 to 23.11)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>123 more per 1000</p>
|
|
<p>(from 44 more to 310 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Use of community services (Number with >1 contact with out of hours services)</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>688</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 2.1 (1.65 to 2.69)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">191 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>210 more per 1000</p>
|
|
<p>(from 124 more to 323 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Use of community services (Number with >1 contact with hospice)</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>688</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1 (0.99 to 1.01)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1000 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>0 fewer per 1000</p>
|
|
<p>(from 10 fewer to 10 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Use of community services (Number receiving >1 social service)</td><td headers="hd_h_ch11.tab5_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>688</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab5_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.19 (0.82 to 1.72)</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">136 per 1000</td><td headers="hd_h_ch11.tab5_1_1_1_5 hd_h_ch11.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>26 more per 1000</p>
|
|
<p>(from 24 fewer to 98 more)</p>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.tab5_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.tab5_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11tab6"><div id="ch11.tab6" class="table"><h3><span class="label">Table 6</span><span class="title">Clinical evidence summary: out of hours service (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme with out of hours non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab6/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab6_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.tab6_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_ch11.tab6_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_ch11.tab6_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_ch11.tab6_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_ch11.tab6_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_ch11.tab6_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_ch11.tab6_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.tab6_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_ch11.tab6_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_ch11.tab6_1_1_1_5" id="hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Usual care</th><th headers="hd_h_ch11.tab6_1_1_1_5" id="hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Delivering Choice Programme with OOH (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - acute hospital)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.32 (0.26 to 0.39)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">427 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>290 fewer per 1000</p>
|
|
<p>(from 260 fewer to 316 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - community hospital)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 3.18 (1.95 to 5.18)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>35 more per 1000</p>
|
|
<p>(from 15 more to 67 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - home)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.37 (1.26 to 1.5)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">398 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>147 more per 1000</p>
|
|
<p>(from 103 more to 199 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - care home)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.06 (0.8 to 1.41)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>5 more per 1000</p>
|
|
<p>(from 18 fewer to 36 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - hospice)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 5.66 (4.12 to 7.77)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>130 more per 1000</p>
|
|
<p>(from 87 more to 190 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - elsewhere)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, indirectness, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 2.12 (0.87 to 5.15)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>7 more per 1000</p>
|
|
<p>(from 1 fewer to 25 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (patients with one or more emergency admissions <30 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.85 (0.76 to 0.95)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">447 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>67 fewer per 1000</p>
|
|
<p>(from 22 fewer to 107 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (patients with one or more emergency admissions <7 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.41 (0.32 to 0.53)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">239 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>141 fewer per 1000</p>
|
|
<p>(from 112 fewer to 163 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (mean emergency admissions per patient <30 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;"></td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <30 days) in the control groups was 0.45</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <30 days) in the intervention groups was 0.08 higher (0.02 to 0.14 higher)</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (mean emergency admissions per patient <7 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <7 days) in the control groups was 0.25</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <7 days) in the intervention groups was 0.14 lower (0.17 to 0.11 lower)</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (patients with one or more ED attendance <30 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup> due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.71 (0.61 to 0.82)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">364 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>106 fewer per 1000</p>
|
|
<p>(from 66 fewer to 142 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (patients with one or more ED attendance <7 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">RR 0.32 (0.23 to 0.43)</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">221 per 1000</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>150 fewer per 1000</p>
|
|
<p>(from 126 fewer to 170 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (mean ED attendance per patient <30 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;"></td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <30 days) in the control groups was 0.41</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <30 days) in the intervention groups was 0.02 lower (0.07 lower to 0.03 higher)</td></tr><tr><td headers="hd_h_ch11.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (mean ED attendance per patient <7 days)</td><td headers="hd_h_ch11.tab6_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>2572</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup> due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab6_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <7 days) in the control groups was 0.26</td><td headers="hd_h_ch11.tab6_1_1_1_5 hd_h_ch11.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <7 days) in the intervention groups was 0.19 lower (0.22 to 0.16 lower)</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.tab6_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.tab6_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>c</dt><dd><div id="ch11.tab6_3"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11tab7"><div id="ch11.tab7" class="table"><h3><span class="label">Table 7</span><span class="title">Clinical evidence summary: out of hours service (Delivering Choice Programme with out of hours users) versus other service (Delivering Choice Programme without out of hours users) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab7/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab7_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.tab7_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_ch11.tab7_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_ch11.tab7_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_ch11.tab7_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_ch11.tab7_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_ch11.tab7_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_ch11.tab7_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.tab7_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_ch11.tab7_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_ch11.tab7_1_1_1_5" id="hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Delivering Choice Programme without OOH</th><th headers="hd_h_ch11.tab7_1_1_1_5" id="hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Delivering Choice Programme with OOH (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - acute hospital)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.73 (0.52 to 1.02)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">188 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>51 fewer per 1000</p>
|
|
<p>(from 90 fewer to 4 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - home)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.32 (1.11 to 1.58)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">413 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>132 more per 1000</p>
|
|
<p>(from 45 more to 240 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - care home)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>RR</p>
|
|
<p>0.59 (0.4 to 0.87)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">160 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>66 fewer per 1000</p>
|
|
<p>(from 21 fewer to 96 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - hospice)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1 (0.7 to 1.43)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">160 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>0 fewer per 1000</p>
|
|
<p>(from 48 fewer to 69 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - elsewhere)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.16 (0.07 to 0.37)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>67 fewer per 1000</p>
|
|
<p>(from 50 fewer to 74 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (patients with one or more emergency admissions <30 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.32 (1.04 to 1.67)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">286 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>92 more per 1000</p>
|
|
<p>(from 11 more to 192 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (patients with one or more emergency admissions <7 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">RR 1.6 (0.89 to 2.85)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>37 more per 1000</p>
|
|
<p>(from 7 fewer to 113 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (mean emergency admissions per patient <30 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;"></td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <30 days) in the control groups was 0.31</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <30 days) in the intervention groups was 0.22 higher (0.13 to 0.31 higher)</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of hospital visits (mean emergency admissions per patient <7 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <7 days) in the control groups was 0.07</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of hospital visits (mean emergency admissions per patient <7 days) in the intervention groups was 0.04 higher (0 to 0.08 higher)</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (patients with one or more ED attendance <30 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 1.02 (0.78 to 1.33)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">254 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>5 more per 1000</p>
|
|
<p>(from 56 fewer to 84 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (patients with one or more ED attendance <7 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">RR 1.14 (0.63 to 2.08)</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61 per 1000</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>9 more per 1000</p>
|
|
<p>(from 23 fewer to 66 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (mean ED attendance per patient <30 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;"></td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <30 days) in the control groups was 0.27</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <30 days) in the intervention groups was 0.12 higher (0.04 to 0.2 higher)</td></tr><tr><td headers="hd_h_ch11.tab7_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (mean ED attendance per patient <7 days)</td><td headers="hd_h_ch11.tab7_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>829</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup></p>
|
|
<p>due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab7_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <7 days) in the control groups was 0.07</td><td headers="hd_h_ch11.tab7_1_1_1_5 hd_h_ch11.tab7_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean number of visits to A&E (mean ED attendance per patient <7 days) in the intervention groups was 0 higher (0.04 lower to 0.04 higher)</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.tab7_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.tab7_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>c</dt><dd><div id="ch11.tab7_3"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11tab8"><div id="ch11.tab8" class="table"><h3><span class="label">Table 8</span><span class="title">Clinical evidence summary: out of hours service (Palliative home care service) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab8/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab8_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.tab8_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_ch11.tab8_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_ch11.tab8_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_ch11.tab8_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_ch11.tab8_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_ch11.tab8_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_ch11.tab8_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.tab8_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relat ive effect (95% CI)</th><th id="hd_h_ch11.tab8_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_ch11.tab8_1_1_1_5" id="hd_h_ch11.tab8_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Usual care</th><th headers="hd_h_ch11.tab8_1_1_1_5" id="hd_h_ch11.tab8_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Palliative home care service (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - hospital)</td><td headers="hd_h_ch11.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>402</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.31 (0.23 to 0.42)</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">736 per 1000</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>508 fewer per 1000</p>
|
|
<p>(from 427 fewer to 567 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - country hospital)</td><td headers="hd_h_ch11.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>402</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup> due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 2.42 (1.31 to 4.47)</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62 per 1000</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>88 more per 1000</p>
|
|
<p>(from 19 more to 215 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - home)</td><td headers="hd_h_ch11.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>402</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 6.85 (4.34 to 10.79)</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79 per 1000</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>462 more per 1000</p>
|
|
<p>(from 264 more to 773 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - nursing home)</td><td headers="hd_h_ch11.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>402</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup><sup>,</sup><sup>c</sup><sup>,</sup><sup>d</sup></p>
|
|
<p>due to risk of bias, indirectness, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">RR 0.66 (0.35 to 1.22)</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">124 per 1000</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>42 fewer per 1000</p>
|
|
<p>(from 81 fewer to 27 more)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospitalisation (number of hospitalisations in last 2 months of life)</td><td headers="hd_h_ch11.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>402</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean hospitalisation (number of hospitalisations in last 2 months of life) in the control groups was 1.3</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean hospitalisation (number of hospitalisations in last 2 months of life) in the intervention groups was 0.9 lower (1.07 to 0.73 lower)</td></tr><tr><td headers="hd_h_ch11.tab8_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Length of stay (time spent in hospital in the last 2 months of life)</td><td headers="hd_h_ch11.tab8_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>402</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab8_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean length of stay (time spent in hospital in the last 2 months of life) in the control groups was 19.6</td><td headers="hd_h_ch11.tab8_1_1_1_5 hd_h_ch11.tab8_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The mean length of stay (time spent in hospital in the last 2 months of life) in the intervention groups was 15.2 lower (18.08 to 12.32 lower)</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.tab8_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.tab8_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>c</dt><dd><div id="ch11.tab8_3"><p class="no_margin">The majority of the evidence was based on indirect intervention.</p></div></dd></dl><dl class="bkr_refwrap"><dt>d</dt><dd><div id="ch11.tab8_4"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11tab9"><div id="ch11.tab9" class="table"><h3><span class="label">Table 9</span><span class="title">Clinical evidence summary: out of hours service (Specialist palliative care team) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab9/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab9_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.tab9_1_1_1_1" rowspan="2" colspan="1" headers="hd_h_ch11.tab9_1_1_1_1" style="text-align:left;vertical-align:bottom;">Outcomes</th><th id="hd_h_ch11.tab9_1_1_1_2" rowspan="2" colspan="1" headers="hd_h_ch11.tab9_1_1_1_2" style="text-align:left;vertical-align:bottom;">No of Participants (studies) Follow up</th><th id="hd_h_ch11.tab9_1_1_1_3" rowspan="2" colspan="1" headers="hd_h_ch11.tab9_1_1_1_3" style="text-align:left;vertical-align:bottom;">Quality of the evidence (GRADE)</th><th id="hd_h_ch11.tab9_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.tab9_1_1_1_4" style="text-align:left;vertical-align:bottom;">Relative effect (95% CI)</th><th id="hd_h_ch11.tab9_1_1_1_5" colspan="2" rowspan="1" style="text-align:left;vertical-align:bottom;">Anticipated absolute effects</th></tr><tr><th headers="hd_h_ch11.tab9_1_1_1_5" id="hd_h_ch11.tab9_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk with Usual care</th><th headers="hd_h_ch11.tab9_1_1_1_5" id="hd_h_ch11.tab9_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Risk difference with Specialist Palliative Care team (95% CI)</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab9_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Preferred and actual place of death (Place of death - hospital)</td><td headers="hd_h_ch11.tab9_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>6218</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab9_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>b</sup></p>
|
|
<p>due to risk of bias, indirectness</p>
|
|
</td><td headers="hd_h_ch11.tab9_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.57 (0.51 to 0.63)</td><td headers="hd_h_ch11.tab9_1_1_1_5 hd_h_ch11.tab9_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>285 per</p>
|
|
<p>1000</p>
|
|
</td><td headers="hd_h_ch11.tab9_1_1_1_5 hd_h_ch11.tab9_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>123 fewer per 1000</p>
|
|
<p>(from 105 fewer to 140 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab9_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospitalisation (last 2 weeks of life)</td><td headers="hd_h_ch11.tab9_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>6218</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab9_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup><sup>,</sup><sup>c</sup></p>
|
|
<p>due to risk of bias, imprecision</p>
|
|
</td><td headers="hd_h_ch11.tab9_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.80 (0.74 to 0.85)</td><td headers="hd_h_ch11.tab9_1_1_1_5 hd_h_ch11.tab9_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">392 per 1000</td><td headers="hd_h_ch11.tab9_1_1_1_5 hd_h_ch11.tab9_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>78 fewer per 1000</p>
|
|
<p>(from 59 fewer to 102 fewer)</p>
|
|
</td></tr><tr><td headers="hd_h_ch11.tab9_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Number of visits to A&E (last two weeks of life)</td><td headers="hd_h_ch11.tab9_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>6218</p>
|
|
<p>(1 study)</p>
|
|
</td><td headers="hd_h_ch11.tab9_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>⊕⊝⊝⊝</p>
|
|
<p>VERY LOW<sup>a</sup> due to risk of bias</p>
|
|
</td><td headers="hd_h_ch11.tab9_1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">RR 0.84 (0.78 to 0.9)</td><td headers="hd_h_ch11.tab9_1_1_1_5 hd_h_ch11.tab9_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">344 per 1000</td><td headers="hd_h_ch11.tab9_1_1_1_5 hd_h_ch11.tab9_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<p>55 fewer per 1000</p>
|
|
<p>(from 34 fewer to 76 fewer)</p>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.tab9_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.tab9_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>c</dt><dd><div id="ch11.tab9_3"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11tab10"><div id="ch11.tab10" class="table"><h3><span class="label">Table 10</span><span class="title">Total costs of the out-of-hours community services included in the costing analysis</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab10/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab10_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Out-of-hours community services</th><th id="hd_h_ch11.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Total cost<sup>(a)</sup></th><th id="hd_h_ch11.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Source</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">End of life care coordination service</td><td headers="hd_h_ch11.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£642,335</td><td headers="hd_h_ch11.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Original costing analysis *</td></tr><tr><td headers="hd_h_ch11.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Out of hours, end of life advice line</td><td headers="hd_h_ch11.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£138,424</td><td headers="hd_h_ch11.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Original costing analysis *</td></tr><tr><td headers="hd_h_ch11.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Out of hours, end of life, medication provision service</td><td headers="hd_h_ch11.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£7,464</td><td headers="hd_h_ch11.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Original costing analysis *</td></tr><tr><td headers="hd_h_ch11.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">End of Life ambulance</td><td headers="hd_h_ch11.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£100,000</td><td headers="hd_h_ch11.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Original costing analysis *</td></tr><tr><td headers="hd_h_ch11.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospice at home service</td><td headers="hd_h_ch11.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£873,023</td><td headers="hd_h_ch11.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Original costing analysis *</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>(a)</dt><dd><div id="ch11.tab10_1"><p class="no_margin">these costs were estimated assuming that 0.8% of a population of approximately 265,000 people would have access to the services (*please see the End of Life Care costing analysis report, saved separately on the NICE website for details on why the figure of 0.8% was used)</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11tab11"><div id="ch11.tab11" class="table"><h3><span class="label">Table 11</span><span class="title">Potential cost savings resulting from implementing the additional end-of-life out-of-hours community services</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab11/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab11_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.tab11_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcome</th><th id="hd_h_ch11.tab11_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Estimated cost saved</th><th id="hd_h_ch11.tab11_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Source</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab11_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Death occurring outside hospital instead of in hospital</td><td headers="hd_h_ch11.tab11_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£958</td><td headers="hd_h_ch11.tab11_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">120</td></tr><tr><td headers="hd_h_ch11.tab11_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inpatient day reduced in an end of life emergency admission</td><td headers="hd_h_ch11.tab11_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£254</td><td headers="hd_h_ch11.tab11_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">132</td></tr><tr><td headers="hd_h_ch11.tab11_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">End of life emergency admission avoided</td><td headers="hd_h_ch11.tab11_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">£2,919</td><td headers="hd_h_ch11.tab11_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">132</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11tab12"><div id="ch11.tab12" class="table"><h3><span class="label">Table 12</span><span class="title">Threshold Analysis Results</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.tab12/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.tab12_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.tab12_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">Service</th><th id="hd_h_ch11.tab12_1_1_1_2" colspan="3" rowspan="1" style="text-align:left;vertical-align:bottom;">Percentage reduction in outcomes required to make the service cost neutral</th></tr></thead><tbody><tr><td headers="hd_h_ch11.tab12_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Deaths in Hospital</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inpatient Days in Emergency Admissions</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Emergency Admissions</td></tr><tr><td headers="hd_h_ch11.tab12_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">End of life care coordination service</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6%</td></tr><tr><td headers="hd_h_ch11.tab12_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Out of hours, end of life advice line</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1%</td></tr><tr><td headers="hd_h_ch11.tab12_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Out of hours, end of life, medication provision service</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">0.3%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">0.07%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">0.07%</td></tr><tr><td headers="hd_h_ch11.tab12_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">End of Life ambulance</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1%</td></tr><tr><td headers="hd_h_ch11.tab12_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospice at home service</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8%</td><td headers="hd_h_ch11.tab12_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8%</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appatab1"><div id="ch11.appa.tab1" class="table"><h3><span class="label">Table 13</span><span class="title">Review protocol for what are the best out of hours services, models and policies to support people in their last year of life to stay in their usual place of residence?</span></h3><div class="caption"><p>Question number: 13</p><p>Relevant section of Scope: Service delivery models for end of life care, including both acute, community and third sector settings covering:
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<ul id="ch11.l9"><li id="ch11.lt34" class="half_rhythm"><div>types of services (supportive and palliative care) provided by generalists and specialists during the course of the last year of life,</div></li><li id="ch11.lt35" class="half_rhythm"><div>who delivers the services and how, multidisciplinary team composition,</div></li><li id="ch11.lt36" class="half_rhythm"><div>timing and review of service provision,</div></li><li id="ch11.lt37" class="half_rhythm"><div>location of services, for example, place of care,</div></li><li id="ch11.lt38" class="half_rhythm"><div>out of hours, weekend and 24/7 availability of services.</div></li></ul></p><p>Field names are based on <a href="http://www.prisma-statement.org/Extensions/Protocols.aspx" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">PRISMA-P</a>.]</p></div><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appa.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appa.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">ID</th><th id="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Field</th><th id="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Content</th></tr></thead><tbody><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">I</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review question</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">What are the best out of hours services, models and policies to support people in their last year of life to stay in their usual place of residence</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">II</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Type of review question</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Intervention review.</p>
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<p>A review of health economic evidence related to the same review question was conducted in parallel with this review. For details see the health economic review protocol for this NICE guideline.</p>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">III</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Objective of the review</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">To identify what are the best out of hours services, models and policies to support people in their last year of life to stay in their usual place of residence</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">IV</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – population / disease / condition / issue / domain</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adults (aged 18 or over) with progressive life-limiting conditions thought to be entering the last year of life.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">V</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – intervention(s) / exposure(s) / prognostic factor(s)</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Out of hours service, such as for example
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<ul id="ch11.l10"><li id="ch11.lt39" class="half_rhythm"><div>Helplines</div></li><li id="ch11.lt40" class="half_rhythm"><div>Parameics</div></li><li id="ch11.lt41" class="half_rhythm"><div>District nurses</div></li><li id="ch11.lt42" class="half_rhythm"><div>Rapid visiting system (GPs)</div></li><li id="ch11.lt43" class="half_rhythm"><div>Out of hours GP</div></li><li id="ch11.lt44" class="half_rhythm"><div>Social workers</div></li><li id="ch11.lt45" class="half_rhythm"><div>Allied health professionals</div></li><li id="ch11.lt46" class="half_rhythm"><div>Equipment store</div></li><li id="ch11.lt47" class="half_rhythm"><div>Dedicated ambulances</div></li><li id="ch11.lt48" class="half_rhythm"><div>24/7 palliative care services</div></li><li id="ch11.lt49" class="half_rhythm"><div>Emergency care and treatment plans/crisis management</div></li><li id="ch11.lt50" class="half_rhythm"><div>Telehealth</div></li><li id="ch11.lt51" class="half_rhythm"><div>Any combination of the above</div></li></ul></p>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VI</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – comparator(s) / control or reference (gold) standard</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch11.l11"><li id="ch11.lt52" class="half_rhythm"><div>Other service (not OOH)</div></li><li id="ch11.lt53" class="half_rhythm"><div>Usual care</div></li></ul></td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Outcomes and prioritisation</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><p>CRITICAL
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<ul id="ch11.l12"><li id="ch11.lt54" class="half_rhythm"><div>Quality of life (Continuous)</div></li><li id="ch11.lt55" class="half_rhythm"><div>Preferred and actual place of death (Dichotomous)</div></li><li id="ch11.lt56" class="half_rhythm"><div>Preferred and actual place of care (Dichotomous)</div></li></ul></p>
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<p>IMPORTANT
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<ul id="ch11.l13"><li id="ch11.lt57" class="half_rhythm"><div>Length of survival (Continuous)</div></li><li id="ch11.lt58" class="half_rhythm"><div>Length of stay (Continuous)</div></li><li id="ch11.lt59" class="half_rhythm"><div>Hospitalisation (Dichotomous)</div></li><li id="ch11.lt60" class="half_rhythm"><div>Number of hospital visits (Dichotomous)</div></li><li id="ch11.lt61" class="half_rhythm"><div>Number of visits to accident and emergency (Dichotomous)</div></li><li id="ch11.lt62" class="half_rhythm"><div>Number of unscheduled admissions (Dichotomous)</div></li><li id="ch11.lt63" class="half_rhythm"><div>Use of community services (Dichotomous)</div></li><li id="ch11.lt64" class="half_rhythm"><div>Avoidable/inappropriate admissions to ICU (Dichotomous)</div></li><li id="ch11.lt65" class="half_rhythm"><div>Avoidable/inappropriate admissions to ICU (Dichotomous)</div></li><li id="ch11.lt66" class="half_rhythm"><div>Inappropriate attempts at cardiopulmonary resuscitation (Dichotomous)</div></li><li id="ch11.lt67" class="half_rhythm"><div>Staff satisfaction (continuous)</div></li><li id="ch11.lt68" class="half_rhythm"><div>Patient/carer reported outcomes (satisfaction) (continuous)</div></li></ul></p></td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">VIII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Eligibility criteria – study design</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch11.l14"><li id="ch11.lt69" class="half_rhythm"><div>Systematic reviews</div></li><li id="ch11.lt70" class="half_rhythm"><div>RCTs</div></li><li id="ch11.lt71" class="half_rhythm"><div>Non-randomised comparative studies, including before and after studies and interrupted-time-series</div></li></ul></td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">IX</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Other inclusion exclusion criteria</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch11.l15"><li id="ch11.lt72" class="half_rhythm"><div>Children (17 years or younger)</div></li><li id="ch11.lt73" class="half_rhythm"><div>Studies will only be included if they reported one or more of the outcomes listed above</div></li><li id="ch11.lt74" class="half_rhythm"><div>Descriptive (non-comparative) studies will be excluded</div></li></ul></td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">X</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Proposed sensitivity / subgroup analysis, or meta-regression</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Subgroup analyses if there is heterogeneity:
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<ul id="ch11.l16"><li id="ch11.lt75" class="half_rhythm"><div>Younger adults (aged 18-25)</div></li><li id="ch11.lt76" class="half_rhythm"><div>Frail elderly</div></li><li id="ch11.lt77" class="half_rhythm"><div>People with dementia</div></li><li id="ch11.lt78" class="half_rhythm"><div>People with hearing loss</div></li><li id="ch11.lt79" class="half_rhythm"><div>People in prisons</div></li><li id="ch11.lt80" class="half_rhythm"><div>Socioeconomic inequalities (people from lower income brackets)</div></li><li id="ch11.lt81" class="half_rhythm"><div>Homeless people/vulnerably housed</div></li><li id="ch11.lt82" class="half_rhythm"><div>Travellers</div></li><li id="ch11.lt83" class="half_rhythm"><div>People with learning difficulties</div></li><li id="ch11.lt84" class="half_rhythm"><div>People with disabilities</div></li><li id="ch11.lt85" class="half_rhythm"><div>People with mental health problems</div></li><li id="ch11.lt86" class="half_rhythm"><div>Migrant workers</div></li><li id="ch11.lt87" class="half_rhythm"><div>LGBT</div></li><li id="ch11.lt88" class="half_rhythm"><div>People in whom life-prolonging therapies are still an active option</div></li><li id="ch11.lt89" class="half_rhythm"><div>People from ethnic minorities (BAME)</div></li></ul></td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XI</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Selection process – duplicate screening / selection / analysis</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>This question will be double reviewed in full including double sift and quality assessment. Quality assurance will be undertaken by a senior research fellow prior to completion.</p>
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<p>Review strategy/other analysis:
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<ul id="ch11.l17"><li id="ch11.lt90" class="half_rhythm"><div>Information on identification tools used as part of a service will be extracted.</div></li><li id="ch11.lt91" class="half_rhythm"><div>Due to the expected complexity of the service models implemented in the studies, studies will be reported separately if necessary. In such case, studies on the populations included in the subgroup list will be highlighted to the Committee and will be considered when making the recommendations</div></li></ul></p>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data management (software)</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<ul id="ch11.l18"><li id="ch11.lt92" class="half_rhythm"><div>Pairwise meta-analyses were performed using Cochrane Review Manager (RevMan5).</div></li><li id="ch11.lt93" class="half_rhythm"><div>GRADEpro was used to assess the quality of evidence for each outcome.</div></li><li id="ch11.lt94" class="half_rhythm"><div>Endnote was used for:
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<ul id="ch11.l19" class="circle"><li id="ch11.lt95" class="half_rhythm"><div>Bibliography, citations, sifting and reference management</div></li></ul></div></li><li id="ch11.lt96" class="half_rhythm"><div>Evibase was used for
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<ul id="ch11.l20" class="circle"><li id="ch11.lt97" class="half_rhythm"><div>Data extraction and quality assessment / critical appraisal</div></li></ul></div></li></ul></td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Information sources – databases and dates</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">
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<p>Clinical search databases to be used: Medline, Embase, Cochrane Library, Current Nursing and Allied Health Literature (CINAHL), PsycINFO, Healthcare Management Information Consortium (HMIC), Social Policy and Practice (SSP), Applied Social Sciences Index and Abstracts (ASSIA)</p>
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<p>Date: All years</p>
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<p>Health economics search databases to be used: Medline, Embase, NHSEED, HTA</p>
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<p>Date: Medline, Embase from 2014</p>
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<p>NHSEED, HTA – All years</p>
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<p>Language: Restrict to English only</p>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIV</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Identify if an update</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not applicable.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XV</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Author contacts</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a href="https://www.nice.org.uk/guidance/indevelopment/gid-cgwave0799" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.nice.org<wbr style="display:inline-block"></wbr>​.uk/guidance/indevelopment<wbr style="display:inline-block"></wbr>​/gid-cgwave0799</a>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVI</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Highlight if amendment to previous protocol</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see section 4.5 of <a href="https://www.nice.org.uk/article/pmg20/chapter/4-Developing-review-questions-and-planning-the-evidence-review#planning-the-evidence-review" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search strategy – for one database</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see <a href="#ch11.appb">Appendix B</a></td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XVIII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data collection process – forms / duplicate</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A standardised evidence table format can be found in <a href="#ch11.appd">Appendix D</a>.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XIX</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Data items – define all variables to be collected</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see evidence tables in <a href="#ch11.appd">Appendix D</a> (clinical evidence tables) or <a href="#ch11.appg">G</a> (health economic evidence tables).</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XX</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Methods for assessing bias at outcome / study level</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Standard study checklists were used to critically appraise individual studies. For details please see section 6.2 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a></p>
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<p>The risk of bias across all available evidence was evaluated for each outcome using an adaptation of the ‘Grading of Recommendations Assessment, Development and Evaluation (GRADE) toolbox’ developed by the international GRADE working group <a href="http://www.gradeworkinggroup.org/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.gradeworkinggroup.org/</a></p>
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<p>[Please document any deviations/alternative approach when GRADE isn’t used or if a modified GRADE approach has been used for non-intervention or non-comparative studies.]</p>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXI</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Criteria for quantitative synthesis</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see section 6.4 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Methods for quantitative analysis – combining studies and exploring (in)consistency</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see the separate <a href="/books/NBK558771/bin/bm1.pdf">Methods</a> report for this guideline.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meta-bias assessment – publication bias, selective reporting bias</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>For details please see section 6.2 of <a href="https://www.nice.org.uk/article/pmg20/chapter/6-Reviewing-research-evidence#assessing-the-quality-of-the-evidence" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIV</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Confidence in cumulative evidence</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see sections 6.4 and 9.1 of <a href="https://www.nice.org.uk/article/pmg20/chapter/1-Introduction-and-overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXV</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rationale / context – what is known</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">For details please see the introduction to the evidence review.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVI</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Describe contributions of authors and guarantor</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>A multidisciplinary committee</p>
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<p>[<a href="https://www.nice.org.uk/guidance/indevelopment/gidc-gwave0799" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.nice.org<wbr style="display:inline-block"></wbr>​.uk/guidance/indevelopment<wbr style="display:inline-block"></wbr>​/gidc-gwave0799</a>] developed the evidence review. The committee was convened by the National Guideline Centre (NGC) and chaired by Mark Thomas in line with section 3 of <a href="https://www.nice.org.uk/article/pmg20/chapter/1%20Introduction%20and%20overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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<p>Staff from NGC undertook systematic literature searches, appraised the evidence, conducted meta-analysis and cost-effectiveness analysis where appropriate, and drafted the evidence review in collaboration with the committee. For details please see <a href="https://www.nice.org.uk/article/pmg20/chapter/1-Introduction-and-overview" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Developing NICE guidelines: the manual</a>.</p>
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</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sources of funding / support</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NGC is funded by NICE and hosted by the Royal College of Physicians.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXVIII</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Name of sponsor</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NGC is funded by NICE and hosted by the Royal College of Physicians.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXIX</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Roles of sponsor</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NICE funds NGC to develop guidelines for those working in the NHS, public health and social care in England.</td></tr><tr><td headers="hd_h_ch11.appa.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">XXX</td><td headers="hd_h_ch11.appa.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PROSPERO registration number</td><td headers="hd_h_ch11.appa.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not registered</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appatab2"><div id="ch11.appa.tab2" class="table"><h3><span class="label">Table 14</span><span class="title">Health economic review protocol</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appa.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appa.tab2_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review question</th><th id="hd_h_ch11.appa.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:bottom;">All questions – health economic evidence</th></tr></thead><tbody><tr><th headers="hd_h_ch11.appa.tab2_1_1_1_1" id="hd_b_ch11.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Objectives</th><td headers="hd_h_ch11.appa.tab2_1_1_1_2 hd_b_ch11.appa.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">To identify health economic studies relevant to any of the review questions.</td></tr><tr><th headers="hd_h_ch11.appa.tab2_1_1_1_1" id="hd_b_ch11.appa.tab2_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search criteria</th><td headers="hd_h_ch11.appa.tab2_1_1_1_2 hd_b_ch11.appa.tab2_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Populations, interventions and comparators must be as specified in the clinical review protocol above.</p>
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<p>Studies must be of a relevant health economic study design (cost–utility analysis, cost-effectiveness analysis, cost–benefit analysis, cost–consequences analysis, comparative cost analysis).</p>
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<p>Studies must not be a letter, editorial or commentary, or a review of health economic evaluations. (Recent reviews will be ordered although not reviewed. The bibliographies will be checked for relevant studies, which will then be ordered.)</p>
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<p>Unpublished reports will not be considered unless submitted as part of a call for evidence.</p>
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<p>Studies must be in English.</p>
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</td></tr><tr><th headers="hd_h_ch11.appa.tab2_1_1_1_1" id="hd_b_ch11.appa.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search strategy</th><td headers="hd_h_ch11.appa.tab2_1_1_1_2 hd_b_ch11.appa.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">A health economic study search will be undertaken using population-specific terms and a health economic study filter – see <a href="#ch11.appg">Appendix G</a> [in the Full guideline]</td></tr><tr><th headers="hd_h_ch11.appa.tab2_1_1_1_1" id="hd_b_ch11.appa.tab2_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Review strategy</th><td headers="hd_h_ch11.appa.tab2_1_1_1_2 hd_b_ch11.appa.tab2_1_1_4_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Studies not meeting any of the search criteria above will be excluded. Studies published before 2007, abstract-only studies and studies from non-OECD countries or the USA will also be excluded.</p>
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<p>Each remaining study will be assessed for applicability and methodological limitations using the NICE economic evaluation checklist which can be found in <a href="#ch11.apph">Appendix H</a> of Developing NICE guidelines: the manual (2014).<a class="bibr" href="#ch11.ref121" rid="ch11.ref121"><sup>121</sup></a></p>
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<p>Inclusion and exclusion criteria</p>
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<p>If a study is rated as both ‘Directly applicable’ and with ‘Minor limitations’ then it will be included in the guideline. A health economic evidence table will be completed and it will be included in the health economic evidence profile.</p>
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<p>If a study is rated as either ‘Not applicable’ or with ‘Very serious limitations’ then it will usually be excluded from the guideline. If it is excluded then a health economic evidence table will not be completed and it will not be included in the health economic evidence profile.</p>
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<p>If a study is rated as ‘Partially applicable’, with ‘Potentially serious limitations’ or both then there is discretion over whether it should be included.</p>
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<p>Where there is discretion</p>
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<p>The health economist will make a decision based on the relative applicability and quality of the available evidence for that question, in discussion with the guideline committee if required. The ultimate aim is to include health economic studies that are helpful for decision-making in the context of the guideline and the current NHS setting. If several studies are considered of sufficiently high applicability and methodological quality that they could all be included, then the health economist, in discussion with the committee if required, may decide to include only the most applicable studies and to selectively exclude the remaining studies. All studies excluded on the basis of applicability or methodological limitations will be listed with explanation as excluded health economic studies in Appendix M.</p>
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<p>The health economist will be guided by the following hierarchies.</p>
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<p>Setting:</p>
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<p>UK NHS (most applicable).</p>
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<p>OECD countries with predominantly public health insurance systems (for example, France, Germany, Sweden).</p>
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<p>OECD countries with predominantly private health insurance systems (for example, Switzerland).</p>
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<p>Studies set in non-OECD countries or in the USA will be excluded before being assessed for applicability and methodological limitations.</p>
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<p>Health economic study type:</p>
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<p>Cost–utility analysis (most applicable).</p>
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<p>Other type of full economic evaluation (cost–benefit analysis, cost-effectiveness analysis, cost–consequences analysis).</p>
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<p>Comparative cost analysis.</p>
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<p>Non-comparative cost analyses including cost-of-illness studies will be excluded before being assessed for applicability and methodological limitations.</p>
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<p>Year of analysis:</p>
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<p>The more recent the study, the more applicable it will be.</p>
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<p>Studies published in 2007 or later but that depend on unit costs and resource data entirely or predominantly from before 2007 will be rated as ‘Not applicable’.</p>
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<p>Studies published before 2007 will be excluded before being assessed for applicability and methodological limitations.</p>
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<p>Quality and relevance of effectiveness data used in the health economic analysis:</p>
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<p>The more closely the clinical effectiveness data used in the health economic analysis match with the outcomes of the studies included in the clinical review the more useful the analysis will be for decision-making in the guideline.</p>
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</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab1"><div id="ch11.appb.tab1" class="table"><h3><span class="label">Table 15</span><span class="title">Database date parameters and filters used</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Database</th><th id="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dates searched</th><th id="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search filter used</th></tr></thead><tbody><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Medline (Ovid)</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1946 – 04 January 2019</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions</td></tr><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Embase (Ovid)</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1974 – 04 January 2019</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions</td></tr><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The Cochrane Library (Wiley)</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Cochrane Reviews to Issue 1 of 12, January 2019</p>
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<p>CENTRAL to Issue 1 of 12, January 2019</p>
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<p>DARE, and NHSEED to Issue 2 of 4 2015</p>
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<p>HTA to Issue 4 of 4 2016</p>
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</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CINAHL, Current Nursing and Allied Health Literature (EBSCO)</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inception – 04 January 2019</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Limiters - English Language; Exclude MEDLINE records; Publication Type: Clinical Trial, Journal Article, Meta Analysis, Randomized Controlled Trial, Systematic Review: Age Groups: All Adult; Language: English</td></tr><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">PsycINFO (ProQuest)</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inception – 04 January 2019</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study type</td></tr><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">HMIC. Healthcare Management Information Consortium (Ovid)</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1979 – 04 January 2019</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Exclusions</td></tr><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">SPP, Social Policy and Practice</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1981 – 04 January 2019</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study types</td></tr><tr><td headers="hd_h_ch11.appb.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">ASSIA, Applied Social Sciences Index and Abstracts (ProQuest)</td><td headers="hd_h_ch11.appb.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1987 – 04 January 2019</td><td headers="hd_h_ch11.appb.tab1_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab2"><div id="ch11.appb.tab2" class="table"><h3><span class="title">Medline (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab2_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Palliative care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminally Ill/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nursing Homes/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospices/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Continuity of Patient Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Physician-Patient Relations/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long-Term Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Delivery of Health Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-26</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">news/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp historical article/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anecdotes as Topic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">comment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/28-35</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36 not 37</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animals/ not humans/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animals, Laboratory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experimentation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Models, Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodentia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/38-44</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27 not 45</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 46 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 not 48</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">After-Hours Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>((morning* or evening* or weekday or weekend* or 7 day or seven day or seven-day or after-hour* or 24 hour* or 24hour* or twenty-four-hour* or out-of-hour* or 9-5 or</p>
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<p>Monday-Friday or Saturday or Sunday) adj3 (service* or access* or availab* or hour* or appointment* or care or caring or palliativ* or pharmacy* or telephone* or advic* or advis* or consult* or support* or nurs* or speciali* or physician* or doctor* or expert* or professional* or paramedic* or general practioner* or GP* or social worker* or case worker* or ambulance* or health worker* or physiotherapist* or therapist*)).ti,ab.</p>
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</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rapid response.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospital Rapid Response Team/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(critical care adj2 outreach).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">medical emergency team*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital* adj2 home*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospital at night.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(“NHS 111” or “NHS 24” or “NHS Direct”).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp telemedicine/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth* or tele-health* or telemedicine* or tele-medicine* or tele-consult* or tele-consult* or tele-monitor* or telemonitor* or telemanag* or tele-manag* or telepharm* or tele-pharm* or telenurs* or tele-nurs* or tele-homecare or telehomecare or tele-support or telesupport or mobile health or ehealth or e-health or mhealth or m-health).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hotlines/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hotline* or helpline* or help-line* or call cent* or call service*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((email* or e-mail* or telephone* or phone* or video*) adj3 (servic* or advic* or advis* or consult* or support* or care* or caring* or appoint*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/50-63</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 64</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(commission* adj2 (support* or service* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((service* or program* or co-ordinat* or co ordinat* or coordinat*) adj2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Critical Pathways/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((critical or clinic* or service* or care) adj2 path*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Patient Care Bundles/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(care adj2 (bundle* or service* or package* or standard*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/66-71</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(assess* or criteria* or predict* or recogni* or identif* or refer*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 72 and 73</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">gold standard*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 75</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(amber adj2 bundle).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74 or 76 or 77</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">patient care team/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">interdisciplinary communication/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((integrat* or network*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(key adj2 work*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj2 (lead or leader or leads or facilitat*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj1 profession*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Case Management/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(case adj2 manage*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(co-ordinator* or coordinator* or coordinate* or co-ordinate*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/79-88</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">interdisciplinary communication/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Communication Barriers/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(communicat* or discuss* or speak* or talk* or convers* or contact).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((handover or hand over or share or shared or sharing or transfer*) adj3 information*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(followup or follow up).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(palliativ* adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/90-95</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 89 and 96</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Social Welfare/ec, ed, es, eh, ma, st, sn, td [Economics, Education, Ethics, Ethnology, Manpower, Standards, Statistics & Numerical Data, Trends]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Charities/ec, ed, es, ma, mt, og, st, sn, sd, td, ut [Economics, Education, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Home Care Services/ec, ed, es, ma, mt, og, st, sn, sd, td, ut [Economics, Education, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Community Health Nursing/ec, ed, es, ma, mt, og, st, sn, sd, td, ut [Economics, Education, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Telemedicine/ec, es, ma, mt, og, st, sn, td, ut [Economics, Ethics, Manpower, Methods, Organization & Administration, Standards, Statistics & Numerical Data, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp remote consultation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*telemedicine/ or *telepathology/ or *teleradiology/ or *telerehabilitation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telemedicine or tele medicine or telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or telepathology or teleradiology or telerehabilitatio).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((tele* or remote) adj2 consult*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mobile Health Units/ec, es, ma, og, st, sn, sd, td, ut [Economics, Ethics, Manpower, Organization & Administration, Standards, Statistics & Numerical Data, Supply & Distribution, Trends, Utilization]</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(mobile adj2 (health or care) adj2 unit*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">109.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital-based home care or HBHC or hospital-based hospice care or acute hospital care).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">110.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital adj3 (domicil* or home)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">111.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home hospitali*ation.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">112.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Home Care Agencies/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">113.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(social adj (welfare or care)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">114.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* adj4 (home-visit* or home visit* or home-based or home based)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">115.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) adj nurs*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">116.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(community adj2 (health care or healthcare or nursing or nurse*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">117.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali*ation* or admission* or readmission* or admit*) adj3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">118.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/98-117</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">119.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Continuity of Patient Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">120.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Aftercare/ or *Patient discharge/ or *Patient handoff/ or *Patient transfer/ or *Transitional care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">121.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Patient Discharge Summaries/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">122.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((patient* or person* or people or nursing* or clinic*) adj (discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">123.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or caring or serv*) adj2 (continu* or change* or transition* or transfer*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">124.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(discharg* adj2 (facilitat* or rapid* or pathway* or path way* or plan* or program*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">125.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/119-124</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">126.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Advance Care Planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">127.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">128.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">129.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/126-128</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">130.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Caregivers/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">131.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Spouses/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">132.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Family/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">133.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">134.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/130-133</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">135.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((replacement or break* or holiday* or respite) adj3 (care* or service*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">136.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((communit* or support* or psychosocial* or psycholog*) adj3 (service* or group* or system*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">137.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((group* or support* or psychosocial* or psycholog*) adj3 (selfhelp or self help or therap*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">138.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((psychosocial* or psycholog*) adj2 support*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">139.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Self-Help Groups/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">140.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp social support/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">141.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Counseling/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">142.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(counseling or counselling*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">143.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(buddy* or buddies).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">144.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((health* or medical*) adj2 check*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">145.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*) adj3 (education or educate or educating or information or literature or leaflet* or booklet* or pamphlet* or website* or knowledge)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">146.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/135-145</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">147.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and 134 and 146</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">148.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">“referral and consultation”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">149.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(referral* or referred or referring or refer or refers or consult*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">150.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(recommend* or direct*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">151.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/148-150</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">152.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(service* adj3 (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">153.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and (89 or 125 or 129 or 151 or 152)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">154.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65 or 78 or 97 or 147 or 153</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab3"><div id="ch11.appb.tab3" class="table"><h3><span class="title">Embase (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab3_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Palliative therapy/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminally ill patient/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Nursing home/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Doctor patient relation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long term care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Health care delivery/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-26</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter.pt. or letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">note.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/ or case study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/28-32</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33 not 34</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal/ not human/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">nonhuman/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experiment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Experimental Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodent/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/35-42</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27 not 43</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44 not 45</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 46 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(after hours care or after-hours care).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((morning* or evening* or weekday or weekend* or 7 day or seven day or seven-day or after-hour* or 24 hour* or 24hour* or twenty-four-hour* or out-of-hour* or 9-5 or Monday-Friday or Saturday or Sunday) adj3 (service* or access* or availab* or hour* or appointment* or care or caring or palliativ* or pharmacy* or telephone* or advic* or advis* or consult* or support* or nurs* or speciali* or physician* or doctor* or expert* or professional* or paramedic* or general practioner* or GP* or social worker* or case worker* or ambulance* or health worker* or physiotherapist* or therapist*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rapid response.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rapid response team/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(critical care adj2 outreach).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">medical emergency team*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital* adj2 home*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospital at night.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(“NHS 111” or “NHS 24” or “NHS Direct”).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp telehealth/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth* or tele-health* or telemedicine* or tele-medicine* or tele-consult* or tele-consult* or tele-monitor* or telemonitor* or telemanag* or tele-manag* or telepharm* or tele-pharm* or telenurs* or tele-nurs* or tele-homecare or telehomecare or tele-support or telesupport or mobile health or ehealth or e-health or mhealth or m-health).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">telephone/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hotline* or helpline* or help-line* or call cent* or call service*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((email* or e-mail* or telephone* or phone* or video*) adj3 (servic* or advic* or advis* or consult* or support* or care* or caring* or appoint*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/48-61</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 and 62</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(commission* adj2 (support* or service* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((service* or program* or co-ordinat* or co ordinat* or coordinat*) adj2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Clinical Pathway/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((critical or clinic* or service* or care) adj2 path*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Care Bundle/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(care adj2 (bundle* or service* or package* or standard*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/64-70</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(assess* or criteria* or predict* or recogni* or identif* or refer*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 and 70 and 71</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">gold standard*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 and 73</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(amber adj2 bundle).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72 or 74 or 75</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">interdisciplinary communication/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">patient care team*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((integrat* or network*) adj2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(key adj2 work*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj2 (lead or leader or leads or facilitat*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) adj1 profession*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Case Management/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(case adj2 manage*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(co-ordinator* or coordinator* or coordinate* or co-ordinate*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/77-86</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88 or 89</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Caregiver/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Spouse/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Family/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/91-94</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((replacement or break* or holiday* or respite) adj3 (care* or service*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((communit* or support* or psychosocial* or psycholog*) adj3 (service* or group* or system*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((group* or support* or psychosocial* or psycholog*) adj3 (selfhelp or self help or therap*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((psychosocial* or psycholog*) adj2 support*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Self-Help/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Social support/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Counseling/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(counseling or counselling*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(buddy* or buddies).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((health* or medical*) adj2 check*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*) adj3 (education or educate or educating or information or literature or leaflet* or booklet* or pamphlet* or website* or knowledge)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/96-106</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 and 95 and 107</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">109.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">interdisciplinary communication/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">110.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(communicat* or discuss* or speak* or talk* or convers* or contact).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">111.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((handover or hand over or share or shared or sharing or transfer*) adj3 information*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">112.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(followup or follow up).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">113.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(palliativ* adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">114.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/109-113</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">115.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 and 87 and 114</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">116.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*social welfare/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">117.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*community health nursing/ or *community care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">118.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*senior center/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">119.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*telemedicine/ or *telehealth/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">120.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*teleconsultation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">121.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or mobile health unit*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">122.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*home care/ or *home health agency/ or *home monitoring/ or *home oxygen therapy/ or *home physiotherapy/ or *home rehabilitation/ or *home respiratory care/ or *respite care/ or *visiting nursing service/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">123.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*health care personnel/ or *health auxiliary/ or *nursing home personnel/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">124.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telemedicine or tele medicine or telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or telepathology or teleradiology or telerehabilitatio).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">125.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((tele* or remote) adj2 consult*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">126.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(mobile adj2 (health or care) adj2 unit*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">127.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital-based home care or HBHC or hospital-based hospice care or acute hospital care).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">128.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital adj3 (domicil* or home)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">129.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home hospitali*ation.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">130.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(social adj (welfare or care)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">131.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* adj4 (home-visit* or home visit* or home-based or home based)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">132.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) adj nurs*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">133.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(community adj2 (health care or healthcare or nursing or nurse*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">134.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali*ation* or admission* or readmission* or admit*) adj3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">135.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/116-134</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">136.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*patient care/ or *case management/ or *patient care planning/ or *rapid response team/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">137.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*aftercare/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">138.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*hospital discharge/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">139.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*clinical handover/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">140.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*transitional care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">141.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">142.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*medical record/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">143.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((patient* or person* or people or nursing* or clinic*) adj (discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">144.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or caring or serv*) adj2 (continu* or change* or transition* or transfer*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">145.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(discharg* adj2 (facilitat* or rapid* or pathway* or path way* or plan* or program*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">146.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Or/136-145</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">147.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp patient referral/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">148.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(referral* or referred or referring or refer or refers or consult*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">149.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(recommend* or direct*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">150.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/147-149</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">151.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(service* adj3 (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">152.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 and (87 or 90 or 135 or 146 or 150 or 151)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">153.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63 or 76 or 108 or 115 or 152</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab4"><div id="ch11.appb.tab4" class="table"><h3><span class="title">Cochrane Library (Wiley) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab4_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Palliative Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Terminal Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Hospice Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Terminally Ill] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) near/2 (care* or caring or ill*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) near (phase* or stage*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Nursing Homes] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) near/2 (home or homes)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Respite Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) near/2 (care or caring)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Hospices] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Care Planning] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Continuity of Patient Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) near/3 (care or caring) near/3 (continu* or plan*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Attitude to Death] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* near/3 (death* or dying*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Physician-Patient Relations] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Long-Term Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Delivery of Health Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end near/2 life):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) near/2 (year or month*) near/2 life):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) near/2 (patient* or person* or people or care or caring)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #1-#26)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [After-Hours Care] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((morning* or evening* or weekday or weekend* or 7 day or seven day or seven-day or after-hour* or 24 hour* or 24hour* or twenty-four-hour* or out-of-hour* or 9-5 or Monday-Friday or Saturday or Sunday) near/3 (service* or access* or availab* or hour* or appointment* or care or caring or palliativ* or pharmacy* or telephone* or advic* or advis* or consult* or support* or nurs* or speciali* or physician* or doctor* or expert* or professional* or paramedic* or general practioner* or GP* or social worker* or case worker* or ambulance* or health worker* or physiotherapist* or therapist*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rapid next response:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Hospital Rapid Response Team] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">medical next emergency next team*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital* near/2 home*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospital next at next night:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(NHS next (111 or 24 or direct)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Telemedicine] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth* or tele-health* or telemedicine* or tele-medicine* or tele-consult* or tele-consult* or tele-monitor* or telemonitor* or telemanag* or tele-manag* or telepharm* or tele-pharm* or telenurs* or tele-nurs* or tele-homecare or telehomecare or tele-support or telesupport or mobile health or ehealth or e-health or mhealth or m-health):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Hotlines] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hotline* or helpline* or help-line* or call cent* or call service*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((email* or e-mail* or telephone* or phone* or video*) near/3 (servic* or advic* or advis* or consult* or support* or care* or caring* or appoint*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #28-#40)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27 and #41</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(commission* near/2 (support* or service* or model*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((service* or program* or co-ordinat* or co ordinat* or coordinat*) near/2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Critical Pathways] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((critical or clinic* or service* or care) near/2 path*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Care Bundles] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(care near/2 (bundle* or service* or package* or standard*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #43-#38)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(assess* or criteria* or predict* or recogni* or identif* or refer*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27 and #49 and #50</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">gold standard*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27 and #52</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(amber near/2 bundle):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#51 or #53 or #54</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Care Team] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Interdisciplinary Communication] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) near/2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)) or MDT or IDT):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((integrat* or network*) near/2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(key near/2 work*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) near/2 (lead or leader or leads or facilitat*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((healthcare or care) near/1 profession*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Case Management] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(case near/2 manage*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(co-ordinator* or coordinator* or coordinate* or co-ordinate*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #56-#65)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Advance Care Planning] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* near/2 (plan* or decision* or directive*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #67-#69)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Caregivers] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Spouses] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Family] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #71-#74)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((replacement or break* or holiday* or respite) near/3 (care* or service*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((communit* or support* or psychosocial* or psycholog*) near/3 (service* or group* or system*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((group* or support* or psychosocial* or psycholog*) near/3 (selfhelp or self help or therap*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((psychosocial* or psycholog*) near/2 support*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Self-Help Groups] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Social Support] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Counseling] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(counseling or counselling*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(buddy* or buddies):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health or medical*) near/3 check*:ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(spouse* or wife or wives or husband* or carer* or caregiver* or care giver* or significant other* or friend* or partner* or family or families or individual* or sibling* or brother* or sister* or relative or relatives or mothers* or daughters* or father* or son or sons or uncle* or aunt* or grand mother* or grandmother* or grandfather* or grand father* or aunt* or uncle* or cousin* or niece* or nephew*) near/3 (education or educate or educating or information or literature or leaflet* or booklet* or pamphlet* or website* or knowledge):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #76-#86)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27 and #75 and #87</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Interdisciplinary Communication] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Communication Barriers] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(communicat* or discuss* or speak* or talk* or convers* or contact):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((handover or hand over or share or shared or sharing or transfer*) near/3 information*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(followup or follow up):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(palliativ* near/2 (care or caring)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #80-#94)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27 and #66 and #95</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Social Welfare] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Charities] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Adult Day Care Centers] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Community Health Nursing] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Care Services] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Senior Centers] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Telemedicine] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Remote Consultation] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Mobile Health Units] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((community based or community dwelling home or rural) near/3 (care or health care or healthcare)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital-based home care or HBHC or hospital-based hospice care or acute hospital care):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#109.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali*ation* or admission* or readmission* or admit*) near/3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#110.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(home based versus hospital based):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#111.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital near/3 (domicil* or home)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#112.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(home hospitali*ation):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#113.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Care Services, Hospital-Based] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#114.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Health Nursing] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#115.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Homemaker Services] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#116.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Care Agencies] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#117.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Home Health Aides] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#118.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(social care):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#119.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Nurses, Community Health] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#120.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* near/4 (home-visit* or home visit* or home-based or home based)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#121.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) near nurs*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#122.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(Or #97-#121)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#123.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Continuity of Patient Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#124.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Aftercare] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#125.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Discharge] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#126.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Handoff] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#127.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Transfer] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#128.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Transitional Care] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#129.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Patient Discharge Summaries] this term only</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#130.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((patient* or person* or people or nursing* or clinic*) near (discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#131.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or caring or serv*) near/2 (continu* or change* or transition* or transfer*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#132.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(discharg* near/2 (facilitat* or rapid* or pathway* or path way* or plan* or program*)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#133.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #123-#132)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#134.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Referral and Consultation] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#135.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(referral* or referred or referring or refer or refers or consult*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#136.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(recommend* or direct*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#137.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(or #134-#136)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#138.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">service* near/3 (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#139.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27 and (#66 or #70 or #122 or #133 or #137 or #138)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#140.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#42 or #55 or #88 or #96 or #139</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab5"><div id="ch11.appb.tab5" class="table"><h3><span class="title">CINAHL (EBSCO) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab5/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab5_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Palliative care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Terminal care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Hospice care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI palliat* OR AB palliat*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MW Terminally ill</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (terminal* or long term or longterm) AND TI (care* or caring or ill*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (terminal* or long term or longterm) AND AB (care* or caring or ill*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (dying or terminal) AND TI (phase* or stage*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (dying or terminal) AND AB (phase* or stage*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI life limit* OR AB life limit*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Nursing homes</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (care or nursing) AND TI (home or homes)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (care or nursing) AND AB (home or homes)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Respite care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (respite or day) AND TI (care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (respite or day) AND AB (care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Hospices</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI Hospice* OR AB Hospice*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Patient Care Plans”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Continuity of Patient Care”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (advance* or patient*) AND TI (care or caring) AND TI (continu* or plan*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (advance* or patient*) AND AB (care or caring) AND AB (continu* or plan*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Attitude to Death</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI attitude* AND TI (death* or dying)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB attitude* AND AB (death* or dying)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Physician-Patient Relations</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Long Term Care”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Health Care Delivery”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI end AND TI life OR AB end AND AB life</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI EOLC OR AB EOLC</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (last or final) AND TI (year or month) AND TI life</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (last or final) AND AB (year or month) AND AB life</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (dying or death) AND TI (patient* or person* or people or care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (dying or death) AND AB (patient* or person* or people or care or caring)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">out of hours care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((morning* or evening* or weekday or weekend* or 7 day or seven day or seven-day or after-hour* or 24 hour* or 24hour* or twenty-four-hour* or out-of-hour* or 9-5 or Monday-Friday or Saturday or Sunday) n3 (service* or access* or availab* or hour* or appointment* or care or caring or palliativ* or pharmacy* or telephone* or advic* or advis* or consult* or support* or nurs* or speciali* or physician* or doctor* or expert* or professional* or paramedic* or general practioner* or GP* or social worker* or case worker* or ambulance* or health worker* or physiotherapist* or therapist*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rapid response</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(critical care n2 outreach) OR medical emergency team* OR (hospital* n2 home*) OR hospital at night</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">NHS 111 OR NHS 24 OR NHS Direct</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Telemedicine”) OR (MH “Telehealth”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(telehealth* or tele-health* or telemedicine* or tele-medicine* or tele-consult* or tele-consult* or tele-monitor* or telemonitor* or telemanag* or tele-manag* or telepharm* or tele-pharm* or telenurs* or tele-nurs* or tele-homecare or telehomecare or tele-support or telesupport or mobile health or ehealth or e-health or mhealth or m-health)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Telephone Information Services”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hotline* or helpline* or help-line* or call cent* or call service*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((email* or e-mail* or telephone* or phone* or video*) n3 (servic* or advic* or advis* or consult* or support* or care* or caring* or appoint*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44 OR S45</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S35 AND S46</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI commission* AND TI ((support* or service* or model*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB commission* AND AB ((support* or service* or model*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (service* or program* or co-ordinat* or co ordinat* or coordinat*) AND TI (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (service* or program* or co-ordinat* or co ordinat* or coordinat*) AND AB (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (critical or clinic* or service* or care) AND TI path*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (critical or clinic* or service* or care) AND AB path*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI care AND TI (bundle* or service* or package* or standard*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB care AND AB (bundle* or service* or package* or standard*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S48 OR S49 OR S50 OR S51 OR S52 OR S53 OR S54 OR S55</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (assess* or criteria* or predict* or recogni* or identif* or refer*) OR AB (assess* or criteria* or predict* or recogni* or identif* or refer*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S35 AND S56 AND S57</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI gold standard* OR AB gold standard*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S35 AND S59</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI amber AND TI bundle</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB amber AND AB bundle</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S61 OR S62</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S58 OR S60 OR S63</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Multidisciplinary Care Team+”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MDT OR IDT</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((interdisciplin* or inter-disciplin* or interprofession* or inter-profession* or multidisciplin* or multi-disciplin* or multi-profession* or multiprofession* or transprofession* or trans-profession*) n2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((integrat* or network*) n2 (team* or staff* or meeting* or manag* or appointment* or system* or program* or practic* or advic* or advis* or caring or intervention* or ward* or round* or panel* or forum* or fora or communicat* or collaborat* or relat*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (key n2 work*) OR AB (key n2 work*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (((healthcare or care) n2 (lead or leader or leads or facilitat*))) OR AB (((healthcare or care) n2 (lead or leader or leads or facilitat*)))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (((healthcare or care) n1 profession*)) OR AB (((healthcare or care) n1 profession*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Case Management</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (case n2 manage*) OR AB (case n2 manage*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI ((co-ordinator* or coordinator* or coordinate* or co-ordinate*)*)) OR AB ((co-ordinator* or coordinator* or coordinate* or co-ordinate*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S65 OR S66 OR S67 OR S68 OR S69 OR S70 OR S71 OR S72 OR S73 OR S74</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI advance* AND TI (plan* or decision* or directive*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB advance* AND AB (plan* or decision* or directive*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S76 OR S77</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Interdisciplinary Communication] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH descriptor: [Communication Barriers] explode all trees</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(communicat* or discuss* or speak* or talk* or convers* or contact):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((handover or hand over or share or shared or sharing or transfer*) near/3 information*):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(followup or follow up):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(palliativ* near/2 (care or caring)):ti,ab</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S79 OR S80 OR S81 OR S82 OR S83 OR S84</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S35 AND S75 AND S85</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Social Welfare”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Charities”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Adult Day Center (Saba CCC)”) OR (MM “Housing for the Elderly”) OR (MM “Older Adult Care (Saba CCC)”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Community Health Nursing+”) OR (MM “Community Health Centers”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>(MH “Home Health Care+”) OR (MM “Home Health Aides”) OR (MM “Home Health</p>
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<p>Care Information Systems”) OR (MM “Home Health Aide Service (Saba CCC)”)</p>
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</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Housing for the Elderly”) OR (MM “Rural Health Centers”) OR (MM “Community Health Centers”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Telemedicine+”) OR (MH “Telehealth+”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>(MM “Remote Consultation”) OR (MM “Telephone Consultation (Iowa NIC)”) OR (MM</p>
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<p>“Services for Australian Rural and Remote Allied Health”)</p>
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</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">telehealth or tele health or virtual hospital* or helpline* or help line* or rapid response team* or senior center*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Rural Health Personnel”) OR (MM “Mobile Health Units”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">remote consultation</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((community based or community dwelling home or rural) n3 (care or health care or healthcare))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospital-based home care or HBHC or hospital-based hospice care or acute hospital care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((hospitali?ation* or admission* or readmission* or admit*) n3 (reduc* or avoid* or prevent* or inappropiate or increase* or risk*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S101.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home based versus hospital based</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S102.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospital n3 (domicil* or home))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S103.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home hospitali?ation</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S104.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">home care service*</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S105.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Home Health Agencies”) OR (MM “Nursing Home Personnel”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S106.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Homemaker Services”) OR (MM “Health Services for the Aged”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S107.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>(MH “Home Health Care+”) OR (MM “Home Care Equipment and Supplies”) OR (MH</p>
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<p>“Nursing Homes”) OR (MM “National Association for Home Care & Hospice”) OR (MM “Nursing Home Patients”)</p>
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</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S108.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">social care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S109.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Hospitals, Community”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S110.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Home Nursing”) OR (MM “Home Nursing, Professional”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S111.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nurs* n4 (home-visit* or home visit* or home-based or home based))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S112.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((district* or communit* or home or visit*) n nurs*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S113.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>S87 OR S88 OR S89 OR S90 OR S91 OR S92 OR S93 OR S94 OR S95 OR S96 OR</p>
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<p>S97 OR S98 OR S99 OR S100 OR S101 OR S102 OR S103 OR S104 OR S105 OR</p>
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<p>S106 OR S107 OR S108 OR S109 OR S110 OR S111 OR S112</p>
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</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S114.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MH Continuity of Patient Care OR MH Aftercare OR MH Patient discharge OR MH Patient handoff OR MH Patient transfer OR MH Transitional care</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S115.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MM “Discharge Planning”) OR (MM “Patient Discharge Summaries”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S116.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (((patient* or person* or people or nursing* or clinic*)) AND TX ((discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S117.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB (((patient* or person* or people or nursing* or clinic*)) AND AB ((discharg* or handover* or hand* over* or handoff* or hand off* or signout* or sign* out* or signover* or sign* over*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S118.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB ((care or caring or serv*)) AND AB ((continu* or change* or transition* or transfer*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S119.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI ((care or caring or serv*)) AND TI ((continu* or change* or transition* or transfer*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S120.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI discharg* AND TI (facilitat* or rapid* or pathway* or path way* or plan* or program*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S121.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB discharg* AND AB (facilitat* or rapid* or pathway* or path way* or plan* or program*))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S122.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S1114 OR S115 OR S116 OR S117 OR S118 OR S119 OR S120 OR S121</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S123.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(MH “Referral and Consultation+”)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S124.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (referral* or referred or referring or refer or refers or consult*) OR AB (referral* or referred or referring or refer or refers or consult*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S125.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TI (recommend* or direct*) OR AB (recommend* or direct*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S126.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S123 OR S124 OR S125</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S127.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TX service* AND TX (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S128.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">AB service* AND AB (provision* or deliver* or addition* or method* or time* or timing or frequent* or frequenc* or review* or ident* or assess*)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S129.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S127 OR S128</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S130.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S35 AND (S75 OR S78 OR S113 OR S122 OR S126 OR S129)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S131.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">S47 OR S64 OR S86 OR S130</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab6"><div id="ch11.appb.tab6" class="table"><h3><span class="title">PsycINFO (ProQuest) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab6/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab6_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(ti,ab(commission* NEAR/2 (support* OR service* OR model*)) OR ((service* OR program* OR co-ordinat* OR coordinat*) NEAR/2 (model* OR deliver* OR strateg* OR support* OR access* OR method* OR system* OR policies OR policy OR availab*))) AND (SU.EXACT(“Palliative Care”) OR SU.EXACT(“Terminally Ill Patients”) OR SU.EXACT(“Hospice”) OR ti,ab(palliat*) OR ti,ab((terminal* OR long-term OR longterm) NEAR/2 (care* OR caring OR ill*)) OR ti,ab((dying OR terminal) NEAR/1 (phase* OR stage*)) OR ti,ab(life-limit*) OR SU.EXACT(“Nursing Homes”) OR ti,ab((care OR nursing) NEAR/2 (home OR homes)) OR SU.EXACT(“Respite Care”) OR ti,ab((respite OR day) NEAR/2 (care OR caring)) OR ti,ab(hospice*) OR MJSUB.EXACT(“Treatment Planning”) OR MJSUB.EXACT(“Continuum of Care”) OR ti,ab((advance* OR patient*) NEAR/3 (care OR caring) NEAR/3 (continu* OR plan*)) OR MJSUB.EXACT(“Long Term Care”) OR ti,ab(attitude* NEAR/3 (death* OR dying*)) OR ti,ab(end NEAR/2 life) OR ti,ab(EOLC) OR ti,ab((last OR final) NEAR/2 (year OR month*) NEAR/2 life) OR ti,ab((dying OR death) NEAR/2 (patient* OR person* OR people OR care OR caring)))</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adolescence (13-17 Yrs), Adulthood (18 Yrs & Older), Aged (65 Yrs & Older), Middle Age (40-64 Yrs), Thirties (30-39 Yrs), Very Old (85 Yrs & Older), Young Adulthood (18-29 Yrs)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1 and 2</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference Proceedings, Journal Article, Peer Reviewed Journal</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3 and 4</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab7"><div id="ch11.appb.tab7" class="table"><h3><span class="title">HMIC (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab7/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab7_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp End of life care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(terminal* adj ill*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/2-8</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp Paediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp older people/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">not 10</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 11 to English</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 12 to (audiovis or book or chapter dh helmis or circular or microfiche dh helmis or multimedias or website)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 12 to (audiocass or books or cdrom or chapter or dept pubs or diskettes or folio pamp or “map” or marc or microfiche or multimedia or pamphlet or parly or press or press rel or thesis or trustdoc or video or videos or website)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or 14</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">not 15</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">euthanasia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">euthanasia.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or 18</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">not 19</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab8"><div id="ch11.appb.tab8" class="table"><h3><span class="title">SPP (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab8/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab8_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(nursing adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(terminal* adj2 ill*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(respite adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-15</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(child* or infant*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(adult* or adolescent*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17 not 18</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16 not 19</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 20 to (journal or journal article or online resource or online report or report)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab9"><div id="ch11.appb.tab9" class="table"><h3><span class="title">ASSIA (ProQuest) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab9/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab9_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab. ((ti,ab(commission* N/2 (support* or service* or model*)) OR ti,ab((service* or program* or co-ordinat* or coordinat*) N/2 (model* or deliver* or strateg* or support* or access* or method* or system* or policies or policy or availab*))) AND ((SU.EXACT(“Care” OR “Clinical nursing” OR “Community homes” OR “Community nursery nursing” OR “Community nursing” OR “Compassionate care” OR “Continuing care” OR “District nursing” OR “Family centred care” OR “Geriatric wards” OR “Group care” OR “Health visiting” OR “Home care” OR “Home from home care” OR “Home health aides” OR “Home helps” OR “Hospices” OR “Hostel wards” OR “Informal care” OR “Integrated care pathways” OR “Intentional care” OR “Intermediate care” OR “Intermediate care centres” OR “Lack of care” OR “Learning disability nursing” OR “Length of stay” OR “Liaison nursing” OR “Long stay wards” OR “Long term care” OR “Long term home care” OR “Long term residential care” OR “Nurse led care” OR “Nursing” OR “Occupational health nursing” OR “Ontological care” OR “Out of home care” OR “Outreach nursing” OR “Palliative care” OR “Paranursing” OR “Pastoral care” OR “Patient care” OR “Primary nursing” OR “Private residential care” OR “Process centred care” OR “Quality of care” OR “Radical health visiting” OR “Residential care” OR “Residential group care” OR “Respite care” OR “Shared care” OR “Social care” “Temporary care” OR “Terminal care” OR “Wards”) OR (SU.EXACT(“Terminally ill elderly people”) OR SU.EXACT(“Terminally ill fathers”) OR SU.EXACT(“Terminally ill elderly men”) OR SU.EXACT(“Terminally ill elderly women”) OR SU.EXACT(“Terminally ill young adults”) OR SU.EXACT(“Terminally ill parents”) OR SU.EXACT(“Terminally ill women”) OR SU.EXACT(“Terminally ill widowed sisters”) OR SU.EXACT(“Terminally ill colleagues”) OR SU.EXACT(“Terminally ill young girls”) OR SU.EXACT(“Terminally ill people”) OR SU.EXACT(“Terminally ill men”)) OR SU.EXACT(“Advance directives” OR “Do not resuscitate orders” OR “Durable power of attorney for health care” OR “Living wills” OR “Treatment preferences” OR “Treatment needs”)) OR (ti,ab((advance* or patient*) N/3 (care or caring) N/3 (continu* or plan*)) or ti,ab(attitude* N/3 (death* or dying*)) or ti,ab(end N/2 life) or ti,ab(EOLC) or ti,ab((last or final) N/2 (year or month*) N/2 life) or ti,ab((dying or death) N/2 (patient* or person* or people or care or caring))))) OR SU.EXACT(“End of life decisions”)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab10"><div id="ch11.appb.tab10" class="table"><h3><span class="label">Table 16</span><span class="title">Database date parameters and filters used</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab10/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab10_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Database</th><th id="hd_h_ch11.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dates searched</th><th id="hd_h_ch11.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Search filter used</th></tr></thead><tbody><tr><td headers="hd_h_ch11.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Medline</td><td headers="hd_h_ch11.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2014 – 04 January 2019</td><td headers="hd_h_ch11.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Exclusions</p>
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<p>Health economics studies</p>
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<p>Health economics modelling studies</p>
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<p>Quality of life studies</p>
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</td></tr><tr><td headers="hd_h_ch11.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Embase</td><td headers="hd_h_ch11.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2014 – 04 January 2019</td><td headers="hd_h_ch11.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>Exclusions</p>
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<p>Health economics studies</p>
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<p>Health economics modelling studies</p>
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<p>Quality of life studies</p>
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</td></tr><tr><td headers="hd_h_ch11.appb.tab10_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Centre for Research and Dissemination (CRD)</td><td headers="hd_h_ch11.appb.tab10_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<p>HTA - Inception – 04 January 2019</p>
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<p>NHSEED - Inception to March 2015</p>
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</td><td headers="hd_h_ch11.appb.tab10_1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">None</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab11"><div id="ch11.appb.tab11" class="table"><h3><span class="title">Medline (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab11/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab11_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Palliative care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Terminally Ill/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nursing Homes/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hospices/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Advance Care Planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Continuity of Patient Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Physician-Patient Relations/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long-Term Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*“Delivery of Health Care”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-29</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">news/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp historical article/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anecdotes as Topic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">comment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/31-38</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39 not 40</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animals/ not humans/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animals, Laboratory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experimentation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Models, Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodentia/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/41-47</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30 not 48</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 49 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50 not 51</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">economics/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">value of life/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp “costs and cost analysis”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Economics, Hospital/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Economics, medical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Economics, nursing/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">economics, pharmaceutical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp “Fees and Charges”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp budgets/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cost*.ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(economic* or pharmaco?economic*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(price* or pricing*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cost* adj2 (effectiv* or utilit* or benefit* or minimi* or unit* or estimat* or variable*)).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(financ* or fee or fees).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(value adj2 (money or monetary)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/53-68</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp models, economic/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Models, Theoretical/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Models, Organizational/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">markov chains/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">monte carlo method/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Decision Theory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(markov* or monte carlo).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">econom* model*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(decision* adj2 (tree* or analy* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/70-78</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">quality-adjusted life years/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(quality adj2 (wellbeing or well being)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">disability adjusted life.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qal* or qtime* or qwb* or daly*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(euroqol* or eq5d* or eq 5*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qol* or hql* or hqol* or h qol* or hrqol* or hr qol*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health utility* or utility score* or disutilit* or utility value*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hui or hui1 or hui2 or hui3).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health* year* equivalent* or hye or hyes).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">discrete choice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rosser.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(willingness to pay or time tradeoff or time trade off or tto or standard gamble*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf36* or sf 36* or short form 36* or shortform 36* or shortform36*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf20 or sf 20 or short form 20 or shortform 20 or shortform20).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf12* or sf 12* or short form 12* or shortform 12* or shortform12*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf8* or sf 8* or short form 8* or shortform 8* or shortform8*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf6* or sf 6* or short form 6* or shortform 6* or shortform6*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/80-98</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">100.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52 and (69 or 79 or 99)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab12"><div id="ch11.appb.tab12" class="table"><h3><span class="title">Embase (Ovid) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab12/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab12_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Palliative therapy/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminal care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">palliat*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Terminally ill patient/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((terminal* or long term or longterm) adj2 (care* or caring or ill*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or terminal) adj (phase* or stage*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">life limit*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Nursing home/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((care or nursing) adj2 (home or homes)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Respite Care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((respite or day) adj2 (care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Hospice/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">hospice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care planning/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(advance* adj2 (plan* or decision* or directive*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">living will*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Patient care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Attitude to Death/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(attitude* adj3 (death* or dying*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Doctor patient relation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Long term care/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*Health care delivery/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(end adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">EOLC.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((last or final) adj2 (year or month*) adj2 life).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((dying or death) adj2 (patient* or person* or people or care or caring)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/1-28</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">letter.pt. or letter/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">note.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">editorial.pt.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">33.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">case report/ or case study/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">34.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(letter or comment*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/30-34</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">36.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">randomized controlled trial/ or random*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">37.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">35 not 36</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">38.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal/ not human/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">39.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">nonhuman/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">40.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Animal Experiment/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">41.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Experimental Animal/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">42.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">animal model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">43.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp Rodent/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">44.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(rat or rats or mouse or mice).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">45.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/37-44</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">46.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">29 not 45</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">limit 46 to English language</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">48.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(exp child/ or exp pediatrics/ or exp infant/) not (exp adolescent/ or exp adult/ or exp middle age/ or exp aged/)</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">47 not 48</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">50.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">health economics/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">51.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp economic evaluation/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">52.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp health care cost/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">53.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp fee/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">54.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">55.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">funding/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">56.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">budget*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">57.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">cost*.ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">58.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(economic* or pharmaco?economic*).ti.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">59.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(price* or pricing*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">60.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(cost* adj2 (effectiv* or utilit* or benefit* or minimi* or unit* or estimat* or variable*)).ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">61.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(financ* or fee or fees).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">62.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(value adj2 (money or monetary)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">63.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/50-62</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">statistical model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">65.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">exp economic aspect/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">66.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">64 and 65</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">67.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*theoretical model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">68.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">*nonbiological model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">69.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">stochastic model/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">70.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">decision theory/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">71.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">decision tree/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">72.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">monte carlo method/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">73.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(markov* or monte carlo).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">74.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">econom* model*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">75.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(decision* adj2 (tree* or analy* or model*)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">76.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/66-75</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">77.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">quality-adjusted life years/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">78.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">“quality of life index”/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">79.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">short form 12/ or short form 20/ or short form 36/ or short form 8/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">80.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile/</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">81.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(quality adj2 (wellbeing or well being)).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">82.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">sickness impact profile.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">83.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">disability adjusted life.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">84.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qal* or qtime* or qwb* or daly*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">85.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(euroqol* or eq5d* or eq 5*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">86.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(qol* or hql* or hqol* or h qol* or hrqol* or hr qol*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">87.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health utility* or utility score* or disutilit* or utility value*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">88.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hui or hui1 or hui2 or hui3).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">89.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(health* year* equivalent* or hye or hyes).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">90.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">discrete choice*.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">91.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">rosser.ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">92.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(willingness to pay or time tradeoff or time trade off or tto or standard gamble*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">93.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf36* or sf 36* or short form 36* or shortform 36* or shortform36*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">94.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf20 or sf 20 or short form 20 or shortform 20 or shortform20).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">95.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf12* or sf 12* or short form 12* or shortform 12* or shortform12*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">96.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf8* or sf 8* or short form 8* or shortform 8* or shortform8*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">97.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(sf6* or sf 6* or short form 6* or shortform 6* or shortform6*).ti,ab.</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">98.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">or/77-97</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">99.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">49 and (63 or 76 or 98)</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appbtab13"><div id="ch11.appb.tab13" class="table"><h3><span class="title">NHS EED and HTA (CRD) search terms</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appb.tab13/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appb.tab13_lrgtbl__"><table><tbody><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#1.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Palliative Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#2.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Terminal Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#3.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Hospice Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#4.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(palliat*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#5.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Terminally Ill IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#6.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((terminal* or long term or longterm) adj2 (care* or caring or ill*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#7.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((dying or terminal) adj (phase* or stage*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#8.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(life limit*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#9.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Nursing Homes IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#10.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((care or nursing) adj2 (home or homes))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#11.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Respite Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#12.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((respite or day) adj2 (care or caring))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#13.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Hospices IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#14.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(hospice*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#15.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Advance Care Planning EXPLODE ALL TREES IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#16.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((advance* adj2 (plan* or decision* or directive*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#17.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(living will*) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#18.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Patient Care Planning IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#19.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Continuity of Patient Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#20.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((advance* or patient*) adj3 (care or caring) adj3 (continu* or plan*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#21.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Attitude to Death IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#22.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((attitude* adj3 (death* or dying*))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#23.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Physician-Patient Relations IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#24.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Long-Term Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#25.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">MeSH DESCRIPTOR Delivery of Health Care IN NHSEED,HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#26.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">((end adj2 life)) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#27.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(EOLC) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#28.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((last or final) adj2 (year or month*) adj2 life)) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#29.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(((dying or death) adj2 (patient* or person* or people or care or caring))) IN NHSEED, HTA</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#30.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22</p>
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<p>OR #23 OR #24 OR #25 OR #26 OR #27 OR #28 OR #29</p>
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</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#31.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(#30) IN NHSEED</td></tr><tr><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">#32.</td><td rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">(#30) IN HTA</td></tr></tbody></table></div></div></article><article data-type="fig" id="figobch11appcfig1"><div id="ch11.appc.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%201.%20Flow%20chart%20of%20clinical%20study%20selection%20for%20the%20review%20of%20out%20of%20hours%20services.&p=BOOKS&id=558771_ch11appcf1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appcf1.jpg" alt="Figure 1. Flow chart of clinical study selection for the review of out of hours services." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 1</span><span class="title">Flow chart of clinical study selection for the review of out of hours services</span></h3></div></article><article data-type="fig" id="figobch11appefig1"><div id="ch11.appe.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%202.%20Carers%20quality%20of%20life%20(EQ5D%2C%200-1)%20(8%20months).&p=BOOKS&id=558771_ch11appef1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef1.jpg" alt="Figure 2. Carers quality of life (EQ5D, 0-1) (8 months)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 2</span><span class="title">Carers quality of life (EQ5D, 0-1) (8 months)</span></h3></div></article><article data-type="fig" id="figobch11appefig2"><div id="ch11.appe.fig2" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%203.%20Carers%20quality%20of%20life%20(SF12%20Physical%20Component%20Summary%20Score%2C%200-100)%20(8%20months).&p=BOOKS&id=558771_ch11appef2.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef2.jpg" alt="Figure 3. Carers quality of life (SF12 Physical Component Summary Score, 0-100) (8 months)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 3</span><span class="title">Carers quality of life (SF12 Physical Component Summary Score, 0-100) (8 months)</span></h3></div></article><article data-type="fig" id="figobch11appefig3"><div id="ch11.appe.fig3" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%204.%20Carers%20quality%20of%20life%20(SF12%20Mental%20Component%20Summary%20Score%2C%200-100)%20(8%20months).&p=BOOKS&id=558771_ch11appef3.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef3.jpg" alt="Figure 4. Carers quality of life (SF12 Mental Component Summary Score, 0-100) (8 months)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 4</span><span class="title">Carers quality of life (SF12 Mental Component Summary Score, 0-100) (8 months)</span></h3></div></article><article data-type="fig" id="figobch11appefig4"><div id="ch11.appe.fig4" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%205.%20Preferred%20and%20actual%20place%20of%20death%20(N%20achieving%20(initial)%20place%20of%20death).&p=BOOKS&id=558771_ch11appef4.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef4.jpg" alt="Figure 5. Preferred and actual place of death (N achieving (initial) place of death)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 5</span><span class="title">Preferred and actual place of death (N achieving (initial) place of death)</span></h3></div></article><article data-type="fig" id="figobch11appefig5"><div id="ch11.appe.fig5" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%206.%20Preferred%20and%20actual%20place%20of%20death%20(N%20achieving%20(final)%20place%20of%20death).&p=BOOKS&id=558771_ch11appef5.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef5.jpg" alt="Figure 6. Preferred and actual place of death (N achieving (final) place of death)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 6</span><span class="title">Preferred and actual place of death (N achieving (final) place of death)</span></h3></div></article><article data-type="fig" id="figobch11appefig6"><div id="ch11.appe.fig6" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%207.%20Preferred%20and%20actual%20place%20of%20death%20(N%20achieving%20(initial)%20place%20of%20death).&p=BOOKS&id=558771_ch11appef6.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef6.jpg" alt="Figure 7. Preferred and actual place of death (N achieving (initial) place of death)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 7</span><span class="title">Preferred and actual place of death (N achieving (initial) place of death)</span></h3></div></article><article data-type="fig" id="figobch11appefig7"><div id="ch11.appe.fig7" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%208.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(N%20with%20%02265%201%20contact%20with%20acute%20care).&p=BOOKS&id=558771_ch11appef7.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef7.jpg" alt="Figure 8. Number of visits to accident and emergency (N with ≥ 1 contact with acute care)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 8</span><span class="title">Number of visits to accident and emergency (N with ≥ 1 contact with acute care)</span></h3><div class="caption"><p>This outcome included visits to hospital A&E, inpatients nights, outpatients appointments, day hospital visits</p></div></div></article><article data-type="fig" id="figobch11appefig8"><div id="ch11.appe.fig8" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%209.%20Use%20of%20community%20services%20(N%20with%20%02265%201%20contact%20with%20GP%2Fprimary%20care).&p=BOOKS&id=558771_ch11appef8.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef8.jpg" alt="Figure 9. Use of community services (N with ≥ 1 contact with GP/primary care)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 9</span><span class="title">Use of community services (N with ≥ 1 contact with GP/primary care)</span></h3><div class="caption"><p>This outcome included all visits to surgery to see GP or practice nurse, and home visits by GP</p></div></div></article><article data-type="fig" id="figobch11appefig9"><div id="ch11.appe.fig9" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2010.%20Use%20of%20community%20services%20(N%20with%20%02265%201%20contact%20with%20community%20care).&p=BOOKS&id=558771_ch11appef9.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef9.jpg" alt="Figure 10. Use of community services (N with ≥ 1 contact with community care)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 10</span><span class="title">Use of community services (N with ≥ 1 contact with community care)</span></h3><div class="caption"><p>This outcome included all visits and telephone calls to patients by community nurse, long-term condition team, intermediate care teams, community matrons</p></div></div></article><article data-type="fig" id="figobch11appefig10"><div id="ch11.appe.fig10" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2011.%20Use%20of%20community%20services%20(N%20with%20%02265%201%20contact%20with%20Marie%20Curie%20visits).&p=BOOKS&id=558771_ch11appef10.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef10.jpg" alt="Figure 11. Use of community services (N with ≥ 1 contact with Marie Curie visits)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 11</span><span class="title">Use of community services (N with ≥ 1 contact with Marie Curie visits)</span></h3><div class="caption"><p>This outcome included Marie Curie health care assistants or registered nurse visits – each lasted 8 hours (overnight sitting)</p></div></div></article><article data-type="fig" id="figobch11appefig11"><div id="ch11.appe.fig11" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2012.%20Use%20of%20community%20services%20(N%20with%20%02265%201%20contact%20with%20out%20of%20hours%20services).&p=BOOKS&id=558771_ch11appef11.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef11.jpg" alt="Figure 12. Use of community services (N with ≥ 1 contact with out of hours services)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 12</span><span class="title">Use of community services (N with ≥ 1 contact with out of hours services)</span></h3><div class="caption"><p>This outcome included out of hours home visits by GP or nurse, telephone advice by GP, ‘walk-in’ attendances and ambulance responses</p></div></div></article><article data-type="fig" id="figobch11appefig12"><div id="ch11.appe.fig12" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2013.%20Use%20of%20community%20services%20(N%20with%20%02265%201%20contact%20with%20hospice%2C%20excluding%20rapid%20response%20service).&p=BOOKS&id=558771_ch11appef12.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef12.jpg" alt="Figure 13. Use of community services (N with ≥ 1 contact with hospice, excluding rapid response service)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 13</span><span class="title">Use of community services (N with ≥ 1 contact with hospice, excluding rapid response service)</span></h3><div class="caption"><p>This outcome included home or outpatients contacts with hospice nurses, doctors, allied health professionals, social workers, chaplain, inpatient stays, day hospice attendances for complementary therapies</p></div></div></article><article data-type="fig" id="figobch11appefig13"><div id="ch11.appe.fig13" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2014.%20Use%20of%20community%20services%20(N%20receiving%20%02265%201%20social%20service).&p=BOOKS&id=558771_ch11appef13.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef13.jpg" alt="Figure 14. Use of community services (N receiving ≥ 1 social service)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 14</span><span class="title">Use of community services (N receiving ≥ 1 social service)</span></h3><div class="caption"><p>This outcome included social services such as for example domiciliary help, meals</p></div></div></article><article data-type="fig" id="figobch11appefig14"><div id="ch11.appe.fig14" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2015.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20acute%20hospital).&p=BOOKS&id=558771_ch11appef14.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef14.jpg" alt="Figure 15. Preferred and actual place of death (Place of death – acute hospital)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 15</span><span class="title">Preferred and actual place of death (Place of death – acute hospital)</span></h3></div></article><article data-type="fig" id="figobch11appefig15"><div id="ch11.appe.fig15" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2016.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20community%20hospital).&p=BOOKS&id=558771_ch11appef15.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef15.jpg" alt="Figure 16. Preferred and actual place of death (Place of death – community hospital)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 16</span><span class="title">Preferred and actual place of death (Place of death – community hospital)</span></h3></div></article><article data-type="fig" id="figobch11appefig16"><div id="ch11.appe.fig16" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2017.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20home).&p=BOOKS&id=558771_ch11appef16.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef16.jpg" alt="Figure 17. Preferred and actual place of death (Place of death – home)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 17</span><span class="title">Preferred and actual place of death (Place of death – home)</span></h3></div></article><article data-type="fig" id="figobch11appefig17"><div id="ch11.appe.fig17" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2018.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20care%20home).&p=BOOKS&id=558771_ch11appef17.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef17.jpg" alt="Figure 18. Preferred and actual place of death (Place of death – care home)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 18</span><span class="title">Preferred and actual place of death (Place of death – care home)</span></h3></div></article><article data-type="fig" id="figobch11appefig18"><div id="ch11.appe.fig18" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2019.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20hospice).&p=BOOKS&id=558771_ch11appef18.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef18.jpg" alt="Figure 19. Preferred and actual place of death (Place of death – hospice)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 19</span><span class="title">Preferred and actual place of death (Place of death – hospice)</span></h3></div></article><article data-type="fig" id="figobch11appefig19"><div id="ch11.appe.fig19" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2020.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20elsewhere).&p=BOOKS&id=558771_ch11appef19.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef19.jpg" alt="Figure 20. Preferred and actual place of death (Place of death – elsewhere)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 20</span><span class="title">Preferred and actual place of death (Place of death – elsewhere)</span></h3></div></article><article data-type="fig" id="figobch11appefig20"><div id="ch11.appe.fig20" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2021.%20Number%20of%20hospital%20visits%20(patients%20with%20one%20or%20more%20emergency%20admissions%20%3C%2030%20days).&p=BOOKS&id=558771_ch11appef20.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef20.jpg" alt="Figure 21. Number of hospital visits (patients with one or more emergency admissions < 30 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 21</span><span class="title">Number of hospital visits (patients with one or more emergency admissions < 30 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig21"><div id="ch11.appe.fig21" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2022.%20Number%20of%20hospital%20visits%20(patients%20with%20one%20or%20more%20emergency%20admissions%20%3C%207%20days).&p=BOOKS&id=558771_ch11appef21.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef21.jpg" alt="Figure 22. Number of hospital visits (patients with one or more emergency admissions < 7 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 22</span><span class="title">Number of hospital visits (patients with one or more emergency admissions < 7 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig22"><div id="ch11.appe.fig22" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2023.%20Number%20of%20hospital%20visits%20(mean%20emergency%20admission%20per%20patient%20%3C%2030%20days).&p=BOOKS&id=558771_ch11appef22.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef22.jpg" alt="Figure 23. Number of hospital visits (mean emergency admission per patient < 30 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 23</span><span class="title">Number of hospital visits (mean emergency admission per patient < 30 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig23"><div id="ch11.appe.fig23" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2024.%20Number%20of%20hospital%20visits%20(mean%20emergency%20admission%20per%20patient%20%3C%207%20days).&p=BOOKS&id=558771_ch11appef23.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef23.jpg" alt="Figure 24. Number of hospital visits (mean emergency admission per patient < 7 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 24</span><span class="title">Number of hospital visits (mean emergency admission per patient < 7 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig24"><div id="ch11.appe.fig24" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2025.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(patients%20with%20one%20or%20more%20ED%20attendance%20%3C%2030%20days).&p=BOOKS&id=558771_ch11appef24.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef24.jpg" alt="Figure 25. Number of visits to accident and emergency (patients with one or more ED attendance < 30 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 25</span><span class="title">Number of visits to accident and emergency (patients with one or more ED attendance < 30 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig25"><div id="ch11.appe.fig25" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2026.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(patients%20with%20one%20or%20more%20ED%20attendance%20%3C%207%20days).&p=BOOKS&id=558771_ch11appef25.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef25.jpg" alt="Figure 26. Number of visits to accident and emergency (patients with one or more ED attendance < 7 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 26</span><span class="title">Number of visits to accident and emergency (patients with one or more ED attendance < 7 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig26"><div id="ch11.appe.fig26" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2027.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(mean%20ED%20attendance%20per%20patient%20%3C%2030%20days).&p=BOOKS&id=558771_ch11appef26.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef26.jpg" alt="Figure 27. Number of visits to accident and emergency (mean ED attendance per patient < 30 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 27</span><span class="title">Number of visits to accident and emergency (mean ED attendance per patient < 30 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig27"><div id="ch11.appe.fig27" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2028.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(mean%20ED%20attendance%20per%20patient%20%3C%207%20days).&p=BOOKS&id=558771_ch11appef27.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef27.jpg" alt="Figure 28. Number of visits to accident and emergency (mean ED attendance per patient < 7 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 28</span><span class="title">Number of visits to accident and emergency (mean ED attendance per patient < 7 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig28"><div id="ch11.appe.fig28" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2029.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20acute%20hospital).&p=BOOKS&id=558771_ch11appef28.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef28.jpg" alt="Figure 29. Preferred and actual place of death (Place of death – acute hospital)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 29</span><span class="title">Preferred and actual place of death (Place of death – acute hospital)</span></h3></div></article><article data-type="fig" id="figobch11appefig29"><div id="ch11.appe.fig29" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2030.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20home).&p=BOOKS&id=558771_ch11appef29.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef29.jpg" alt="Figure 30. Preferred and actual place of death (Place of death – home)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 30</span><span class="title">Preferred and actual place of death (Place of death – home)</span></h3></div></article><article data-type="fig" id="figobch11appefig30"><div id="ch11.appe.fig30" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2031.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20care%20home).&p=BOOKS&id=558771_ch11appef30.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef30.jpg" alt="Figure 31. Preferred and actual place of death (Place of death – care home)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 31</span><span class="title">Preferred and actual place of death (Place of death – care home)</span></h3></div></article><article data-type="fig" id="figobch11appefig31"><div id="ch11.appe.fig31" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2032.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20hospice).&p=BOOKS&id=558771_ch11appef31.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef31.jpg" alt="Figure 32. Preferred and actual place of death (Place of death – hospice)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 32</span><span class="title">Preferred and actual place of death (Place of death – hospice)</span></h3></div></article><article data-type="fig" id="figobch11appefig32"><div id="ch11.appe.fig32" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2033.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20elsewhere).&p=BOOKS&id=558771_ch11appef32.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef32.jpg" alt="Figure 33. Preferred and actual place of death (Place of death – elsewhere)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 33</span><span class="title">Preferred and actual place of death (Place of death – elsewhere)</span></h3></div></article><article data-type="fig" id="figobch11appefig33"><div id="ch11.appe.fig33" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2034.%20Number%20of%20hospital%20visits%20(patients%20with%20one%20or%20more%20emergency%20admissions%20%3C30%20days).&p=BOOKS&id=558771_ch11appef33.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef33.jpg" alt="Figure 34. Number of hospital visits (patients with one or more emergency admissions <30 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 34</span><span class="title">Number of hospital visits (patients with one or more emergency admissions <30 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig34"><div id="ch11.appe.fig34" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2035.%20Number%20of%20hospital%20visits%20(patients%20with%20one%20or%20more%20emergency%20admissions%20%3C7%20days).&p=BOOKS&id=558771_ch11appef34.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef34.jpg" alt="Figure 35. Number of hospital visits (patients with one or more emergency admissions <7 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 35</span><span class="title">Number of hospital visits (patients with one or more emergency admissions <7 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig35"><div id="ch11.appe.fig35" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2036.%20Number%20of%20hospital%20visits%20(mean%20emergency%20admissions%20per%20patient%20%3C30%20days).&p=BOOKS&id=558771_ch11appef35.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef35.jpg" alt="Figure 36. Number of hospital visits (mean emergency admissions per patient <30 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 36</span><span class="title">Number of hospital visits (mean emergency admissions per patient <30 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig36"><div id="ch11.appe.fig36" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2037.%20Number%20of%20hospital%20visits%20(mean%20emergency%20admissions%20per%20patient%20%3C7%20days).&p=BOOKS&id=558771_ch11appef36.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef36.jpg" alt="Figure 37. Number of hospital visits (mean emergency admissions per patient <7 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 37</span><span class="title">Number of hospital visits (mean emergency admissions per patient <7 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig37"><div id="ch11.appe.fig37" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2038.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(patients%20with%20one%20or%20more%20ED%20attendance%20%3C30days).&p=BOOKS&id=558771_ch11appef37.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef37.jpg" alt="Figure 38. Number of visits to accident and emergency (patients with one or more ED attendance <30days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 38</span><span class="title">Number of visits to accident and emergency (patients with one or more ED attendance <30days)</span></h3></div></article><article data-type="fig" id="figobch11appefig38"><div id="ch11.appe.fig38" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2039.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(patients%20with%20one%20or%20more%20ED%20attendance%20%3C7days).&p=BOOKS&id=558771_ch11appef38.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef38.jpg" alt="Figure 39. Number of visits to accident and emergency (patients with one or more ED attendance <7days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 39</span><span class="title">Number of visits to accident and emergency (patients with one or more ED attendance <7days)</span></h3></div></article><article data-type="fig" id="figobch11appefig39"><div id="ch11.appe.fig39" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2040.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(mean%20ED%20attendance%20per%20patient%20%3C30%20days).&p=BOOKS&id=558771_ch11appef39.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef39.jpg" alt="Figure 40. Number of visits to accident and emergency (mean ED attendance per patient <30 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 40</span><span class="title">Number of visits to accident and emergency (mean ED attendance per patient <30 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig40"><div id="ch11.appe.fig40" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2041.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(mean%20ED%20attendance%20per%20patient%20%3C7%20days).&p=BOOKS&id=558771_ch11appef40.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef40.jpg" alt="Figure 41. Number of visits to accident and emergency (mean ED attendance per patient <7 days)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 41</span><span class="title">Number of visits to accident and emergency (mean ED attendance per patient <7 days)</span></h3></div></article><article data-type="fig" id="figobch11appefig41"><div id="ch11.appe.fig41" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2042.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20-%20hospital).&p=BOOKS&id=558771_ch11appef41.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef41.jpg" alt="Figure 42. Preferred and actual place of death (Place of death - hospital)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 42</span><span class="title">Preferred and actual place of death (Place of death - hospital)</span></h3></div></article><article data-type="fig" id="figobch11appefig42"><div id="ch11.appe.fig42" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2043.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20country%20hospital).&p=BOOKS&id=558771_ch11appef42.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef42.jpg" alt="Figure 43. Preferred and actual place of death (Place of death – country hospital)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 43</span><span class="title">Preferred and actual place of death (Place of death – country hospital)</span></h3></div></article><article data-type="fig" id="figobch11appefig43"><div id="ch11.appe.fig43" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2044.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20home).&p=BOOKS&id=558771_ch11appef43.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef43.jpg" alt="Figure 44. Preferred and actual place of death (Place of death – home)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 44</span><span class="title">Preferred and actual place of death (Place of death – home)</span></h3></div></article><article data-type="fig" id="figobch11appefig44"><div id="ch11.appe.fig44" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2045.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20%02013%20nursing%20home).&p=BOOKS&id=558771_ch11appef44.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef44.jpg" alt="Figure 45. Preferred and actual place of death (Place of death – nursing home)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 45</span><span class="title">Preferred and actual place of death (Place of death – nursing home)</span></h3></div></article><article data-type="fig" id="figobch11appefig45"><div id="ch11.appe.fig45" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2046.%20Hospitalisation%20(number%20of%20hospitalisations%20in%20the%20last%202%20months%20of%20life).&p=BOOKS&id=558771_ch11appef45.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef45.jpg" alt="Figure 46. Hospitalisation (number of hospitalisations in the last 2 months of life)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 46</span><span class="title">Hospitalisation (number of hospitalisations in the last 2 months of life)</span></h3></div></article><article data-type="fig" id="figobch11appefig46"><div id="ch11.appe.fig46" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2047.%20Length%20of%20stay%20(time%20spent%20in%20hospital%20in%20the%20last%202%20months%20of%20life).&p=BOOKS&id=558771_ch11appef46.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef46.jpg" alt="Figure 47. Length of stay (time spent in hospital in the last 2 months of life)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 47</span><span class="title">Length of stay (time spent in hospital in the last 2 months of life)</span></h3></div></article><article data-type="fig" id="figobch11appefig47"><div id="ch11.appe.fig47" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2048.%20Preferred%20and%20actual%20place%20of%20death%20(Place%20of%20death%20-%20hospital).&p=BOOKS&id=558771_ch11appef47.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef47.jpg" alt="Figure 48. Preferred and actual place of death (Place of death - hospital)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 48</span><span class="title">Preferred and actual place of death (Place of death - hospital)</span></h3></div></article><article data-type="fig" id="figobch11appefig48"><div id="ch11.appe.fig48" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2049.%20Hospitalisation%20(last%202%20weeks%20of%20life).&p=BOOKS&id=558771_ch11appef48.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef48.jpg" alt="Figure 49. Hospitalisation (last 2 weeks of life)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 49</span><span class="title">Hospitalisation (last 2 weeks of life)</span></h3></div></article><article data-type="fig" id="figobch11appefig49"><div id="ch11.appe.fig49" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2050.%20Number%20of%20visits%20to%20accident%20and%20emergency%20(last%20two%20weeks%20of%20life).&p=BOOKS&id=558771_ch11appef49.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appef49.jpg" alt="Figure 50. Number of visits to accident and emergency (last two weeks of life)." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 50</span><span class="title">Number of visits to accident and emergency (last two weeks of life)</span></h3></div></article><article data-type="table-wrap" id="figobch11appftab1"><div id="ch11.appf.tab1" class="table"><h3><span class="label">Table 17</span><span class="title">Clinical evidence profile: out of hours service (Rapid response service available) versus usual care (Rapid response service not available, Rapid response service not available) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appf.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appf.tab1_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.appf.tab1_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_ch11.appf.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_ch11.appf.tab1_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_ch11.appf.tab1_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab1_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_ch11.appf.tab1_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab1_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_ch11.appf.tab1_1_1_1_1" id="hd_h_ch11.appf.tab1_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">No of studies</th><th headers="hd_h_ch11.appf.tab1_1_1_1_1" id="hd_h_ch11.appf.tab1_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Design</th><th headers="hd_h_ch11.appf.tab1_1_1_1_1" id="hd_h_ch11.appf.tab1_1_1_2_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Risk of bias</th><th headers="hd_h_ch11.appf.tab1_1_1_1_1" id="hd_h_ch11.appf.tab1_1_1_2_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Inconsistency</th><th headers="hd_h_ch11.appf.tab1_1_1_1_1" id="hd_h_ch11.appf.tab1_1_1_2_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Indirectness</th><th headers="hd_h_ch11.appf.tab1_1_1_1_1" id="hd_h_ch11.appf.tab1_1_1_2_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Imprecision</th><th headers="hd_h_ch11.appf.tab1_1_1_1_1" id="hd_h_ch11.appf.tab1_1_1_2_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Other considerations</th><th headers="hd_h_ch11.appf.tab1_1_1_1_2" id="hd_h_ch11.appf.tab1_1_1_2_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Rapid Response Service available</th><th headers="hd_h_ch11.appf.tab1_1_1_1_2" id="hd_h_ch11.appf.tab1_1_1_2_9" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Usual care (RRS not available)</th><th headers="hd_h_ch11.appf.tab1_1_1_1_3" id="hd_h_ch11.appf.tab1_1_1_2_10" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_ch11.appf.tab1_1_1_1_3" id="hd_h_ch11.appf.tab1_1_1_2_11" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_h_ch11.appf.tab1_1_1_2_3 hd_h_ch11.appf.tab1_1_1_2_4 hd_h_ch11.appf.tab1_1_1_2_5 hd_h_ch11.appf.tab1_1_1_2_6 hd_h_ch11.appf.tab1_1_1_2_7 hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_h_ch11.appf.tab1_1_1_2_9 hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_h_ch11.appf.tab1_1_1_2_11 hd_h_ch11.appf.tab1_1_1_1_4 hd_h_ch11.appf.tab1_1_1_1_5" id="hd_b_ch11.appf.tab1_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Carers quality of life (EQ5D) 8 months - Rapid response service available versus rapid response service not available (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_3 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_4 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_5 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_6 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_7 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">48</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_9 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">16</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_11 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.05 lower (0.12 lower to 0.02 higher)</td><td headers="hd_h_ch11.appf.tab1_1_1_1_4 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_ch11.appf.tab1_1_1_1_5 hd_b_ch11.appf.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_h_ch11.appf.tab1_1_1_2_3 hd_h_ch11.appf.tab1_1_1_2_4 hd_h_ch11.appf.tab1_1_1_2_5 hd_h_ch11.appf.tab1_1_1_2_6 hd_h_ch11.appf.tab1_1_1_2_7 hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_h_ch11.appf.tab1_1_1_2_9 hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_h_ch11.appf.tab1_1_1_2_11 hd_h_ch11.appf.tab1_1_1_1_4 hd_h_ch11.appf.tab1_1_1_1_5" id="hd_b_ch11.appf.tab1_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Carers quality of life (SF12 Physical) 8 months - Rapid response service available versus rapid response service not available (range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_3 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_4 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_5 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_6 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_7 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">48</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_9 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">16</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_11 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 1.86 higher (0.99 lower to 4.71 higher)</td><td headers="hd_h_ch11.appf.tab1_1_1_1_4 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_ch11.appf.tab1_1_1_1_5 hd_b_ch11.appf.tab1_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_h_ch11.appf.tab1_1_1_2_3 hd_h_ch11.appf.tab1_1_1_2_4 hd_h_ch11.appf.tab1_1_1_2_5 hd_h_ch11.appf.tab1_1_1_2_6 hd_h_ch11.appf.tab1_1_1_2_7 hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_h_ch11.appf.tab1_1_1_2_9 hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_h_ch11.appf.tab1_1_1_2_11 hd_h_ch11.appf.tab1_1_1_1_4 hd_h_ch11.appf.tab1_1_1_1_5" id="hd_b_ch11.appf.tab1_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Carers quality of life (SF12 Mental) 8 months - Rapid response service available versus rapid response service not available (range of scores: 0-100; Better indicated by higher values)</th></tr><tr><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_3 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_4 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_5 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_6 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_7 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">48</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_9 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">16</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_11 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 4.93 lower (8 to 1.86 lower)</td><td headers="hd_h_ch11.appf.tab1_1_1_1_4 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_ch11.appf.tab1_1_1_1_5 hd_b_ch11.appf.tab1_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_h_ch11.appf.tab1_1_1_2_3 hd_h_ch11.appf.tab1_1_1_2_4 hd_h_ch11.appf.tab1_1_1_2_5 hd_h_ch11.appf.tab1_1_1_2_6 hd_h_ch11.appf.tab1_1_1_2_7 hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_h_ch11.appf.tab1_1_1_2_9 hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_h_ch11.appf.tab1_1_1_2_11 hd_h_ch11.appf.tab1_1_1_1_4 hd_h_ch11.appf.tab1_1_1_1_5" id="hd_b_ch11.appf.tab1_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Achieved (initial) place of death) - Rapid response service available versus rapid response service not available</th></tr><tr><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_3 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_4 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_5 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_6 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_7 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>429/688</p>
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<p>(62.4%)</p>
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</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_9 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">61.9%</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.01 (0.9 to 1.13)</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_11 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">6 more per 1000 (from 62 fewer to 80 more)</td><td headers="hd_h_ch11.appf.tab1_1_1_1_4 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_ch11.appf.tab1_1_1_1_5 hd_b_ch11.appf.tab1_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_h_ch11.appf.tab1_1_1_2_3 hd_h_ch11.appf.tab1_1_1_2_4 hd_h_ch11.appf.tab1_1_1_2_5 hd_h_ch11.appf.tab1_1_1_2_6 hd_h_ch11.appf.tab1_1_1_2_7 hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_h_ch11.appf.tab1_1_1_2_9 hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_h_ch11.appf.tab1_1_1_2_11 hd_h_ch11.appf.tab1_1_1_1_4 hd_h_ch11.appf.tab1_1_1_1_5" id="hd_b_ch11.appf.tab1_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Achieved (final) place of death) - Rapid response service available versus rapid response service not available</th></tr><tr><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_1 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_2 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_3 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_4 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_5 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_6 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab1_1_1_1_1 hd_h_ch11.appf.tab1_1_1_2_7 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_8 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>454/688</p>
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<p>(66%)</p>
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</td><td headers="hd_h_ch11.appf.tab1_1_1_1_2 hd_h_ch11.appf.tab1_1_1_2_9 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">69.8%</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_10 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.95 (0.86 to 1.04)</td><td headers="hd_h_ch11.appf.tab1_1_1_1_3 hd_h_ch11.appf.tab1_1_1_2_11 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">35 fewer per 1000 (from 98 fewer to 28 more)</td><td headers="hd_h_ch11.appf.tab1_1_1_1_4 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab1_1_1_1_5 hd_b_ch11.appf.tab1_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.appf.tab1_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.appf.tab1_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11appftab2"><div id="ch11.appf.tab2" class="table"><h3><span class="label">Table 18</span><span class="title">Clinical evidence profile: out of hours service (Rapid response service users) versus usual care (Rapid response service not available, Rapid response service non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appf.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appf.tab2_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.appf.tab2_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_ch11.appf.tab2_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_ch11.appf.tab2_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_ch11.appf.tab2_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab2_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_ch11.appf.tab2_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab2_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1" id="hd_h_ch11.appf.tab2_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">No of studies</th><th headers="hd_h_ch11.appf.tab2_1_1_1_1" id="hd_h_ch11.appf.tab2_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Design</th><th headers="hd_h_ch11.appf.tab2_1_1_1_1" id="hd_h_ch11.appf.tab2_1_1_2_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Risk of bias</th><th headers="hd_h_ch11.appf.tab2_1_1_1_1" id="hd_h_ch11.appf.tab2_1_1_2_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Inconsistency</th><th headers="hd_h_ch11.appf.tab2_1_1_1_1" id="hd_h_ch11.appf.tab2_1_1_2_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Indirectness</th><th headers="hd_h_ch11.appf.tab2_1_1_1_1" id="hd_h_ch11.appf.tab2_1_1_2_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Imprecision</th><th headers="hd_h_ch11.appf.tab2_1_1_1_1" id="hd_h_ch11.appf.tab2_1_1_2_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Other considerations</th><th headers="hd_h_ch11.appf.tab2_1_1_1_2" id="hd_h_ch11.appf.tab2_1_1_2_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Rapid Response Service available</th><th headers="hd_h_ch11.appf.tab2_1_1_1_2" id="hd_h_ch11.appf.tab2_1_1_2_9" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Usual care (RRS not available)</th><th headers="hd_h_ch11.appf.tab2_1_1_1_3" id="hd_h_ch11.appf.tab2_1_1_2_10" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_ch11.appf.tab2_1_1_1_3" id="hd_h_ch11.appf.tab2_1_1_2_11" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Achieved (initial) place of death) - Rapid response service users versus rapid response service non-users)</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>171/247</p>
|
|
<p>(69.2%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">59.2%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.17 (1.04 to 1.31)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">101 more per 1000 (from 24 more to 184 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>⨁◯◯◯</p>
|
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (Number with >1 contact with acute care) - Rapid response service users versus Rapid response service non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>129/247</p>
|
|
<p>(52.2%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">56.5%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.92 (0.8 to 1.07)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">45 fewer per 1000 (from 113 fewer to 40 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Use of community services (Number with >1 contact with GP/primary care) - Rapid response service users versus Rapid response service non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>139/159</p>
|
|
<p>(87.4%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">71.9%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.22 (1.11 to 1.34)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">158 more per 1000 (from 79 more to 244 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Use of community services (Number with >1 contact with community care) - Rapid response service users versus Rapid response service non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>223/247</p>
|
|
<p>(90.3%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">69.4%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.3 (1.21 to 1.4)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">208 more per 1000 (from 146 more to 278 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Use of community services (Number with >1 contact with Marie Curie visits) - Rapid response service users versus Rapid response service non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>33/247</p>
|
|
<p>(13.4%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">1.4%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 9.82 (4.17 to 23.11)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">123 more per 1000 (from 44 more to 310 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Use of community services (Number with >1 contact with out of hours services) - Rapid response service users versus Rapid response service non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>99/247</p>
|
|
<p>(40.1%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">19.1%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 2.1 (1.65 to 2.69)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">210 more per 1000 (from 124 more to 323 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_13_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Use of community services (Number with >1 contact with hospice) - Rapid response service users versus Rapid response service non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>247/247</p>
|
|
<p>(100%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">100%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1 (0.99 to 1.01)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">0 fewer per 1000 (from 10 fewer to 10 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_h_ch11.appf.tab2_1_1_2_3 hd_h_ch11.appf.tab2_1_1_2_4 hd_h_ch11.appf.tab2_1_1_2_5 hd_h_ch11.appf.tab2_1_1_2_6 hd_h_ch11.appf.tab2_1_1_2_7 hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_h_ch11.appf.tab2_1_1_2_9 hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_h_ch11.appf.tab2_1_1_2_11 hd_h_ch11.appf.tab2_1_1_1_4 hd_h_ch11.appf.tab2_1_1_1_5" id="hd_b_ch11.appf.tab2_1_1_15_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Use of community services (N receiving >1 social service) - Rapid response service users versus Rapid response service non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_1 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_2 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_3 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_4 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_5 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_6 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab2_1_1_1_1 hd_h_ch11.appf.tab2_1_1_2_7 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_8 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>40/247</p>
|
|
<p>(16.2%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_2 hd_h_ch11.appf.tab2_1_1_2_9 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">13.6%</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_10 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.19 (0.82 to 1.72)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_3 hd_h_ch11.appf.tab2_1_1_2_11 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">26 more per 1000 (from 24 fewer to 98 more)</td><td headers="hd_h_ch11.appf.tab2_1_1_1_4 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab2_1_1_1_5 hd_b_ch11.appf.tab2_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.appf.tab2_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.appf.tab2_2"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11appftab3"><div id="ch11.appf.tab3" class="table"><h3><span class="label">Table 19</span><span class="title">Clinical evidence profile: out of hours service (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme with out of hours non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appf.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appf.tab3_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.appf.tab3_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_ch11.appf.tab3_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_ch11.appf.tab3_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_ch11.appf.tab3_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab3_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_ch11.appf.tab3_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab3_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1" id="hd_h_ch11.appf.tab3_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">No of studies</th><th headers="hd_h_ch11.appf.tab3_1_1_1_1" id="hd_h_ch11.appf.tab3_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Design</th><th headers="hd_h_ch11.appf.tab3_1_1_1_1" id="hd_h_ch11.appf.tab3_1_1_2_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Risk of bias</th><th headers="hd_h_ch11.appf.tab3_1_1_1_1" id="hd_h_ch11.appf.tab3_1_1_2_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Inconsistency</th><th headers="hd_h_ch11.appf.tab3_1_1_1_1" id="hd_h_ch11.appf.tab3_1_1_2_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Indirectness</th><th headers="hd_h_ch11.appf.tab3_1_1_1_1" id="hd_h_ch11.appf.tab3_1_1_2_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Imprecision</th><th headers="hd_h_ch11.appf.tab3_1_1_1_1" id="hd_h_ch11.appf.tab3_1_1_2_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Other considerations</th><th headers="hd_h_ch11.appf.tab3_1_1_1_2" id="hd_h_ch11.appf.tab3_1_1_2_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Rapid Response Service available</th><th headers="hd_h_ch11.appf.tab3_1_1_1_2" id="hd_h_ch11.appf.tab3_1_1_2_9" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Usual care (RRS not available)</th><th headers="hd_h_ch11.appf.tab3_1_1_1_3" id="hd_h_ch11.appf.tab3_1_1_2_10" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_ch11.appf.tab3_1_1_1_3" id="hd_h_ch11.appf.tab3_1_1_2_11" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - acute hospital) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>84/616</p>
|
|
<p>(13.6%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">42.7%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.32 (0.26 to 0.39)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">290 fewer per 1000 (from 260 fewer to 316 fewer)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - community hospital) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>31/616</p>
|
|
<p>(5%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">1.6%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 3.18 (1.95 to 5.18)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">35 more per 1000 (from 15 more to 67 more)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - home) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) nonusers</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>337/616</p>
|
|
<p>(54.7%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">39.8%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.37 (1.26 to 1.5)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">147 more per 1000 (from 103 more to 199 more)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - care home) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>58/616</p>
|
|
<p>(9.4%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">8.8%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.06 (0.8 to 1.41)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">5 more per 1000 (from 18 fewer to 36 more)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (place of death - hospice) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>98/616</p>
|
|
<p>(15.9%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">2.8%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 5.66 (4.12 to 7.77)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">130 more per 1000 (from 87 more to 190 more)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (place of death - elsewhere) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>8/616</p>
|
|
<p>(1.3%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">0.6%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 2.12 (0.87 to 5.15)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">7 more per 1000 (from 1 fewer to 25 more)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_13_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (patients with one or more emergency admissions <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>233/616</p>
|
|
<p>(37.8%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">44.7%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.85 (0.76 to 0.95)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">67 fewer per 1000 (from 22 fewer to 107 fewer)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_15_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (patients with one or more emergency admissions <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>60/616</p>
|
|
<p>(9.7%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">23.9%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.41 (0.32 to 0.53)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">141 fewer per 1000 (from 112 fewer to 163 fewer)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_17_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (mean emergency admissions per patient <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">1956</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.08 higher (0.02 to 0.14 higher)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_19_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (mean emergency admissions per patient <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">1956</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.14 lower (0.17 to 0.11 lower)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_21_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (patients with one or more ED attendance <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>159/616</p>
|
|
<p>(25.8%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">36.4%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.71 (0.61 to 0.82)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">106 fewer per 1000 (from 66 fewer to 142 fewer)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_23_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (patients with one or more ED attendance <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>43/616</p>
|
|
<p>(7%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">22.1%</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.32 (0.23 to 0.43)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">150 fewer per 1000 (from 126 fewer to 170 fewer)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_25_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (mean ED attendance per patient <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">1956</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.02 lower (0.07 lower to 0.03 higher)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_h_ch11.appf.tab3_1_1_2_3 hd_h_ch11.appf.tab3_1_1_2_4 hd_h_ch11.appf.tab3_1_1_2_5 hd_h_ch11.appf.tab3_1_1_2_6 hd_h_ch11.appf.tab3_1_1_2_7 hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_h_ch11.appf.tab3_1_1_2_9 hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_h_ch11.appf.tab3_1_1_2_11 hd_h_ch11.appf.tab3_1_1_1_4 hd_h_ch11.appf.tab3_1_1_1_5" id="hd_b_ch11.appf.tab3_1_1_27_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (mean ED attendance per patient <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (with out of hours) non-users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_1 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_2 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_3 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_4 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_5 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_6 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab3_1_1_1_1 hd_h_ch11.appf.tab3_1_1_2_7 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_8 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab3_1_1_1_2 hd_h_ch11.appf.tab3_1_1_2_9 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">1956</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_10 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab3_1_1_1_3 hd_h_ch11.appf.tab3_1_1_2_11 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.19 lower (0.22 to 0.16 lower)</td><td headers="hd_h_ch11.appf.tab3_1_1_1_4 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_ch11.appf.tab3_1_1_1_5 hd_b_ch11.appf.tab3_1_1_27_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>1</dt><dd><div id="ch11.appf.tab3_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>2</dt><dd><div id="ch11.appf.tab3_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>3</dt><dd><div id="ch11.appf.tab3_3"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11appftab4"><div id="ch11.appf.tab4" class="table"><h3><span class="label">Table 20</span><span class="title">Clinical evidence profile: out of hours service (Delivering Choice Programme with out of hours users) versus usual care (Delivering Choice Programme without out of hours non-users) in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appf.tab4/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appf.tab4_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.appf.tab4_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_ch11.appf.tab4_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_ch11.appf.tab4_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_ch11.appf.tab4_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab4_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_ch11.appf.tab4_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab4_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1" id="hd_h_ch11.appf.tab4_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">No of studies</th><th headers="hd_h_ch11.appf.tab4_1_1_1_1" id="hd_h_ch11.appf.tab4_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Design</th><th headers="hd_h_ch11.appf.tab4_1_1_1_1" id="hd_h_ch11.appf.tab4_1_1_2_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Risk of bias</th><th headers="hd_h_ch11.appf.tab4_1_1_1_1" id="hd_h_ch11.appf.tab4_1_1_2_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Inconsistency</th><th headers="hd_h_ch11.appf.tab4_1_1_1_1" id="hd_h_ch11.appf.tab4_1_1_2_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Indirectness</th><th headers="hd_h_ch11.appf.tab4_1_1_1_1" id="hd_h_ch11.appf.tab4_1_1_2_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Imprecision</th><th headers="hd_h_ch11.appf.tab4_1_1_1_1" id="hd_h_ch11.appf.tab4_1_1_2_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Other considerations</th><th headers="hd_h_ch11.appf.tab4_1_1_1_2" id="hd_h_ch11.appf.tab4_1_1_2_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Rapid Response Service available</th><th headers="hd_h_ch11.appf.tab4_1_1_1_2" id="hd_h_ch11.appf.tab4_1_1_2_9" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Usual care (RRS not available)</th><th headers="hd_h_ch11.appf.tab4_1_1_1_3" id="hd_h_ch11.appf.tab4_1_1_2_10" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_ch11.appf.tab4_1_1_1_3" id="hd_h_ch11.appf.tab4_1_1_2_11" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - acute hospital) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>84/616</p>
|
|
<p>(13.6%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">18.8%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.73 (0.52 to 1.02)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">51 fewer per 1000 (from 90 fewer to 4 more)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - home) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup><sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>3</sup><sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>337/616</p>
|
|
<p>(54.7%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">41.3%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.32 (1.11 to 1.58)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">132 more per 1000 (from 45 more to 240 more)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>⨁◯◯◯</p>
|
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - care home) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>58/616</p>
|
|
<p>(9.4%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">16%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.59 (0.4 to 0.87)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">66 fewer per 1000 (from 21 fewer to 96 fewer)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - hospice) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>1</sup><sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>98/616</p>
|
|
<p>(15.9%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">16%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1 (0.7 to 1.43)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">0 fewer per 1000 (from 48 fewer to 69 more)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - elsewhere) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>8/616</p>
|
|
<p>(1.3%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">8%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.16 (0.07 to 0.37)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">67 fewer per 1000 (from 50 fewer to 74 fewer)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (patients with one or more emergency admissions <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>233/616</p>
|
|
<p>(37.8%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">28.6%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.32 (1.04 to 1.67)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">92 more per 1000 (from 11 more to 192 more)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_13_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (patients with one or more emergency admissions <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>60/616</p>
|
|
<p>(9.7%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">6.1%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.6 (0.89 to 2.85)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">37 more per 1000 (from 7 fewer to 113 more)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_13_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_15_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (mean emergency admissions per patient <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">213</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.22 higher (0.13 to 0.31 higher)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
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</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_15_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_17_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of hospital visits (mean emergency admissions per patient <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">213</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.04 higher (0 to 0.08 higher)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_17_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_19_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (patients with one or more ED attendance <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>159/616</p>
|
|
<p>(25.8%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">25.4%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.02 (0.78 to 1.33)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">5 more per 1000 (from 56 fewer to 84 more)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_19_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_21_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (patients with one or more ED attendance <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>43/616</p>
|
|
<p>(7%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">6.1%</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 1.14 (0.63 to 2.08)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">9 more per 1000 (from 23 fewer to 66 more)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_21_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_23_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (mean ED attendance per patient <30 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">213</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.12 higher (0.04 to 0.2 higher)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_23_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_h_ch11.appf.tab4_1_1_2_3 hd_h_ch11.appf.tab4_1_1_2_4 hd_h_ch11.appf.tab4_1_1_2_5 hd_h_ch11.appf.tab4_1_1_2_6 hd_h_ch11.appf.tab4_1_1_2_7 hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_h_ch11.appf.tab4_1_1_2_9 hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_h_ch11.appf.tab4_1_1_2_11 hd_h_ch11.appf.tab4_1_1_1_4 hd_h_ch11.appf.tab4_1_1_1_5" id="hd_b_ch11.appf.tab4_1_1_25_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (mean ED attendance per patient <7 days) - Delivering Choice Programme (with out of hours) users versus Delivering Choice Programme (without out of hours) users (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_1 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_2 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_3 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_4 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_5 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_6 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab4_1_1_1_1 hd_h_ch11.appf.tab4_1_1_2_7 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_8 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">616</td><td headers="hd_h_ch11.appf.tab4_1_1_1_2 hd_h_ch11.appf.tab4_1_1_2_9 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">213</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_10 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab4_1_1_1_3 hd_h_ch11.appf.tab4_1_1_2_11 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0 higher (0.04 lower to 0.04 higher)</td><td headers="hd_h_ch11.appf.tab4_1_1_1_4 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
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</td><td headers="hd_h_ch11.appf.tab4_1_1_1_5 hd_b_ch11.appf.tab4_1_1_25_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.appf.tab4_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.appf.tab4_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>c</dt><dd><div id="ch11.appf.tab4_3"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed one MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11appftab5"><div id="ch11.appf.tab5" class="table"><h3><span class="label">Table 21</span><span class="title">Clinical evidence profile: out of hours service (Palliative home care service) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appf.tab5/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appf.tab5_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.appf.tab5_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_ch11.appf.tab5_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_ch11.appf.tab5_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_ch11.appf.tab5_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab5_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_ch11.appf.tab5_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab5_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_ch11.appf.tab5_1_1_1_1" id="hd_h_ch11.appf.tab5_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">No of studies</th><th headers="hd_h_ch11.appf.tab5_1_1_1_1" id="hd_h_ch11.appf.tab5_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Design</th><th headers="hd_h_ch11.appf.tab5_1_1_1_1" id="hd_h_ch11.appf.tab5_1_1_2_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Risk of bias</th><th headers="hd_h_ch11.appf.tab5_1_1_1_1" id="hd_h_ch11.appf.tab5_1_1_2_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Inconsistency</th><th headers="hd_h_ch11.appf.tab5_1_1_1_1" id="hd_h_ch11.appf.tab5_1_1_2_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Indirectness</th><th headers="hd_h_ch11.appf.tab5_1_1_1_1" id="hd_h_ch11.appf.tab5_1_1_2_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Imprecision</th><th headers="hd_h_ch11.appf.tab5_1_1_1_1" id="hd_h_ch11.appf.tab5_1_1_2_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Other considerations</th><th headers="hd_h_ch11.appf.tab5_1_1_1_2" id="hd_h_ch11.appf.tab5_1_1_2_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Rapid Response Service available</th><th headers="hd_h_ch11.appf.tab5_1_1_1_2" id="hd_h_ch11.appf.tab5_1_1_2_9" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Usual care (RRS not available)</th><th headers="hd_h_ch11.appf.tab5_1_1_1_3" id="hd_h_ch11.appf.tab5_1_1_2_10" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_ch11.appf.tab5_1_1_1_3" id="hd_h_ch11.appf.tab5_1_1_2_11" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_h_ch11.appf.tab5_1_1_2_3 hd_h_ch11.appf.tab5_1_1_2_4 hd_h_ch11.appf.tab5_1_1_2_5 hd_h_ch11.appf.tab5_1_1_2_6 hd_h_ch11.appf.tab5_1_1_2_7 hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_h_ch11.appf.tab5_1_1_2_9 hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_h_ch11.appf.tab5_1_1_2_11 hd_h_ch11.appf.tab5_1_1_1_4 hd_h_ch11.appf.tab5_1_1_1_5" id="hd_b_ch11.appf.tab5_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (place of death - hospital) - Palliative home care service versus usual care</th></tr><tr><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_3 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_4 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_5 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>b</sup><sup>,</sup><sup>c</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_6 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_7 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>37/160</p>
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<p>(23.1%)</p>
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</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_9 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">73.6%</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.31 (0.23 to 0.42)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_11 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">508 fewer per 1000 (from 427 fewer to 567 fewer)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_4 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_5 hd_b_ch11.appf.tab5_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_h_ch11.appf.tab5_1_1_2_3 hd_h_ch11.appf.tab5_1_1_2_4 hd_h_ch11.appf.tab5_1_1_2_5 hd_h_ch11.appf.tab5_1_1_2_6 hd_h_ch11.appf.tab5_1_1_2_7 hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_h_ch11.appf.tab5_1_1_2_9 hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_h_ch11.appf.tab5_1_1_2_11 hd_h_ch11.appf.tab5_1_1_1_4 hd_h_ch11.appf.tab5_1_1_1_5" id="hd_b_ch11.appf.tab5_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (place of death - country hospital) - Palliative home care service versus usual care</th></tr><tr><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_3 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_4 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_5 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>b</sup><sup>,</sup><sup>c</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_6 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_7 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>24/160</p>
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<p>(15%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_9 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">6.2%</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 2.42 (1.31 to 4.47)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_11 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">88 more per 1000 (from 19 more to 215 more)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_4 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_5 hd_b_ch11.appf.tab5_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_h_ch11.appf.tab5_1_1_2_3 hd_h_ch11.appf.tab5_1_1_2_4 hd_h_ch11.appf.tab5_1_1_2_5 hd_h_ch11.appf.tab5_1_1_2_6 hd_h_ch11.appf.tab5_1_1_2_7 hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_h_ch11.appf.tab5_1_1_2_9 hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_h_ch11.appf.tab5_1_1_2_11 hd_h_ch11.appf.tab5_1_1_1_4 hd_h_ch11.appf.tab5_1_1_1_5" id="hd_b_ch11.appf.tab5_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (place of death - home) - Palliative home care service versus usual care</th></tr><tr><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_3 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_4 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_5 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>2</sup><sup>b</sup><sup>,</sup><sup>c</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_6 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_7 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>86/160</p>
|
|
<p>(53.8%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_9 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">7.9%</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 6.85 (4.34 to 10.79)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_11 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">462 more per 1000 (from 264 more to 773 more)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_4 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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|
<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_5 hd_b_ch11.appf.tab5_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_h_ch11.appf.tab5_1_1_2_3 hd_h_ch11.appf.tab5_1_1_2_4 hd_h_ch11.appf.tab5_1_1_2_5 hd_h_ch11.appf.tab5_1_1_2_6 hd_h_ch11.appf.tab5_1_1_2_7 hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_h_ch11.appf.tab5_1_1_2_9 hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_h_ch11.appf.tab5_1_1_2_11 hd_h_ch11.appf.tab5_1_1_1_4 hd_h_ch11.appf.tab5_1_1_1_5" id="hd_b_ch11.appf.tab5_1_1_7_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (Place of death - nursing home) - Palliative home care service versus usual care</th></tr><tr><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_3 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_4 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_5 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very serious<sup>b</sup><sup>,</sup><sup>c</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_6 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>d</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_7 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>13/160</p>
|
|
<p>(8.1%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_9 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">12.4%</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.66 (0.35 to 1.22)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_11 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">42 fewer per 1000 (from 81 fewer to 27 more)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_4 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_5 hd_b_ch11.appf.tab5_1_1_7_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_h_ch11.appf.tab5_1_1_2_3 hd_h_ch11.appf.tab5_1_1_2_4 hd_h_ch11.appf.tab5_1_1_2_5 hd_h_ch11.appf.tab5_1_1_2_6 hd_h_ch11.appf.tab5_1_1_2_7 hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_h_ch11.appf.tab5_1_1_2_9 hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_h_ch11.appf.tab5_1_1_2_11 hd_h_ch11.appf.tab5_1_1_1_4 hd_h_ch11.appf.tab5_1_1_1_5" id="hd_b_ch11.appf.tab5_1_1_9_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Hospitalisation (number of hospitalisations in last 2 months of life) - Palliative home care service versus usual care (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_3 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_4 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_5 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_6 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_7 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">160</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_9 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">242</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_11 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 0.9 lower (1.07 to 0.73 lower)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_4 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_5 hd_b_ch11.appf.tab5_1_1_9_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_h_ch11.appf.tab5_1_1_2_3 hd_h_ch11.appf.tab5_1_1_2_4 hd_h_ch11.appf.tab5_1_1_2_5 hd_h_ch11.appf.tab5_1_1_2_6 hd_h_ch11.appf.tab5_1_1_2_7 hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_h_ch11.appf.tab5_1_1_2_9 hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_h_ch11.appf.tab5_1_1_2_11 hd_h_ch11.appf.tab5_1_1_1_4 hd_h_ch11.appf.tab5_1_1_1_5" id="hd_b_ch11.appf.tab5_1_1_11_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Length of stay (time spent in hospital in the last 2 months of life) - Palliative home care service versus usual care (Better indicated by lower values)</th></tr><tr><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_1 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_2 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_3 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_4 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_5 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>c</sup></td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_6 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab5_1_1_1_1 hd_h_ch11.appf.tab5_1_1_2_7 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_8 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">160</td><td headers="hd_h_ch11.appf.tab5_1_1_1_2 hd_h_ch11.appf.tab5_1_1_2_9 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">242</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_10 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">-</td><td headers="hd_h_ch11.appf.tab5_1_1_1_3 hd_h_ch11.appf.tab5_1_1_2_11 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">MD 15.2 lower (18.08 to 12.32 lower)</td><td headers="hd_h_ch11.appf.tab5_1_1_1_4 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
|
<p>⨁◯◯◯</p>
|
|
<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab5_1_1_1_5 hd_b_ch11.appf.tab5_1_1_11_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.appf.tab5_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.appf.tab5_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>c</dt><dd><div id="ch11.appf.tab5_3"><p class="no_margin">The majority of the evidence was based on indirect intervention.</p></div></dd></dl><dl class="bkr_refwrap"><dt>d</dt><dd><div id="ch11.appf.tab5_4"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="table-wrap" id="figobch11appftab6"><div id="ch11.appf.tab6" class="table"><h3><span class="label">Table 22</span><span class="title">Clinical evidence profile: out of hours service (Specialist palliative care team) versus usual care in adults with progressive life-limiting conditions thought to be entering their last year of life</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appf.tab6/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appf.tab6_lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_ch11.appf.tab6_1_1_1_1" colspan="7" rowspan="1" style="text-align:center;vertical-align:middle;">Quality assessment</th><th id="hd_h_ch11.appf.tab6_1_1_1_2" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">No of patients</th><th id="hd_h_ch11.appf.tab6_1_1_1_3" colspan="2" rowspan="1" style="text-align:center;vertical-align:middle;">Effect</th><th id="hd_h_ch11.appf.tab6_1_1_1_4" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab6_1_1_1_4" style="text-align:center;vertical-align:middle;">Quality</th><th id="hd_h_ch11.appf.tab6_1_1_1_5" rowspan="2" colspan="1" headers="hd_h_ch11.appf.tab6_1_1_1_5" style="text-align:center;vertical-align:middle;">Importance</th></tr><tr><th headers="hd_h_ch11.appf.tab6_1_1_1_1" id="hd_h_ch11.appf.tab6_1_1_2_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">No of studies</th><th headers="hd_h_ch11.appf.tab6_1_1_1_1" id="hd_h_ch11.appf.tab6_1_1_2_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Design</th><th headers="hd_h_ch11.appf.tab6_1_1_1_1" id="hd_h_ch11.appf.tab6_1_1_2_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Risk of bias</th><th headers="hd_h_ch11.appf.tab6_1_1_1_1" id="hd_h_ch11.appf.tab6_1_1_2_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Inconsistency</th><th headers="hd_h_ch11.appf.tab6_1_1_1_1" id="hd_h_ch11.appf.tab6_1_1_2_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Indirectness</th><th headers="hd_h_ch11.appf.tab6_1_1_1_1" id="hd_h_ch11.appf.tab6_1_1_2_6" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Imprecision</th><th headers="hd_h_ch11.appf.tab6_1_1_1_1" id="hd_h_ch11.appf.tab6_1_1_2_7" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Other considerations</th><th headers="hd_h_ch11.appf.tab6_1_1_1_2" id="hd_h_ch11.appf.tab6_1_1_2_8" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Rapid Response Service available</th><th headers="hd_h_ch11.appf.tab6_1_1_1_2" id="hd_h_ch11.appf.tab6_1_1_2_9" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Usual care (RRS not available)</th><th headers="hd_h_ch11.appf.tab6_1_1_1_3" id="hd_h_ch11.appf.tab6_1_1_2_10" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Relative (95% CI)</th><th headers="hd_h_ch11.appf.tab6_1_1_1_3" id="hd_h_ch11.appf.tab6_1_1_2_11" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Absolute</th></tr></thead><tbody><tr><th headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_1 hd_h_ch11.appf.tab6_1_1_2_2 hd_h_ch11.appf.tab6_1_1_2_3 hd_h_ch11.appf.tab6_1_1_2_4 hd_h_ch11.appf.tab6_1_1_2_5 hd_h_ch11.appf.tab6_1_1_2_6 hd_h_ch11.appf.tab6_1_1_2_7 hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_8 hd_h_ch11.appf.tab6_1_1_2_9 hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_10 hd_h_ch11.appf.tab6_1_1_2_11 hd_h_ch11.appf.tab6_1_1_1_4 hd_h_ch11.appf.tab6_1_1_1_5" id="hd_b_ch11.appf.tab6_1_1_1_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Preferred and actual place of death (place of death - hospital) - Specialist palliative care team versus usual care</th></tr><tr><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_1 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_2 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_3 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_4 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_5 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>b</sup></td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_6 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_7 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_8 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>503/3109</p>
|
|
<p>(16.2%)</p>
|
|
</td><td headers="hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_9 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">28.5%</td><td headers="hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_10 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.57 (0.51 to 0.63)</td><td headers="hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_11 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">123 fewer per 1000 (from 105 fewer to 140 fewer)</td><td headers="hd_h_ch11.appf.tab6_1_1_1_4 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab6_1_1_1_5 hd_b_ch11.appf.tab6_1_1_1_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">CRITICAL</td></tr><tr><th headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_1 hd_h_ch11.appf.tab6_1_1_2_2 hd_h_ch11.appf.tab6_1_1_2_3 hd_h_ch11.appf.tab6_1_1_2_4 hd_h_ch11.appf.tab6_1_1_2_5 hd_h_ch11.appf.tab6_1_1_2_6 hd_h_ch11.appf.tab6_1_1_2_7 hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_8 hd_h_ch11.appf.tab6_1_1_2_9 hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_10 hd_h_ch11.appf.tab6_1_1_2_11 hd_h_ch11.appf.tab6_1_1_1_4 hd_h_ch11.appf.tab6_1_1_1_5" id="hd_b_ch11.appf.tab6_1_1_3_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Hospitalisation (last 2 weeks of life) - Specialist palliative care team versus usual care</th></tr><tr><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_1 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_2 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_3 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_4 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_5 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_6 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>3</sup><sup>c</sup></td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_7 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_8 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>970/3109</p>
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<p>(31.2%)</p>
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</td><td headers="hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_9 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">39.2%</td><td headers="hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_10 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.80 (0.74 to 0.85)</td><td headers="hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_11 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">78 fewer per 1000 (from 59 fewer to 102 fewer)</td><td headers="hd_h_ch11.appf.tab6_1_1_1_4 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab6_1_1_1_5 hd_b_ch11.appf.tab6_1_1_3_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr><tr><th headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_1 hd_h_ch11.appf.tab6_1_1_2_2 hd_h_ch11.appf.tab6_1_1_2_3 hd_h_ch11.appf.tab6_1_1_2_4 hd_h_ch11.appf.tab6_1_1_2_5 hd_h_ch11.appf.tab6_1_1_2_6 hd_h_ch11.appf.tab6_1_1_2_7 hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_8 hd_h_ch11.appf.tab6_1_1_2_9 hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_10 hd_h_ch11.appf.tab6_1_1_2_11 hd_h_ch11.appf.tab6_1_1_1_4 hd_h_ch11.appf.tab6_1_1_1_5" id="hd_b_ch11.appf.tab6_1_1_5_1" colspan="13" rowspan="1" style="text-align:left;vertical-align:bottom;">Number of visits to A&E (last two weeks of life) - Specialist palliative care team versus usual care</th></tr><tr><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_1 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">1</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_2 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">observational studies</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_3 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">serious<sup>a</sup></td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_4 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious inconsistency</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_5 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious indirectness</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_6 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no serious imprecision</td><td headers="hd_h_ch11.appf.tab6_1_1_1_1 hd_h_ch11.appf.tab6_1_1_2_7 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">none</td><td headers="hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_8 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
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<p>896/3109</p>
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<p>(28.8%)</p>
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|
</td><td headers="hd_h_ch11.appf.tab6_1_1_1_2 hd_h_ch11.appf.tab6_1_1_2_9 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">34.4%</td><td headers="hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_10 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">RR 0.84 (0.78 to 0.9)</td><td headers="hd_h_ch11.appf.tab6_1_1_1_3 hd_h_ch11.appf.tab6_1_1_2_11 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">55 fewer per 1000 (from 34 fewer to 76 fewer)</td><td headers="hd_h_ch11.appf.tab6_1_1_1_4 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">
|
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<p>⨁◯◯◯</p>
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<p>VERY LOW</p>
|
|
</td><td headers="hd_h_ch11.appf.tab6_1_1_1_5 hd_b_ch11.appf.tab6_1_1_5_1" rowspan="1" colspan="1" style="text-align:center;vertical-align:top;">IMPORTANT</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt>a</dt><dd><div id="ch11.appf.tab6_1"><p class="no_margin">Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias</p></div></dd></dl><dl class="bkr_refwrap"><dt>b</dt><dd><div id="ch11.appf.tab6_2"><p class="no_margin">The majority of the evidence had indirect outcomes (preferred place of death not reported)</p></div></dd></dl><dl class="bkr_refwrap"><dt>c</dt><dd><div id="ch11.appf.tab6_3"><p class="no_margin">Downgraded by 1 increment if the confidence interval crossed 1 MID or downgraded by 2 increments if the confidence interval crossed both MIDs</p></div></dd></dl></dl></div></div></div></article><article data-type="fig" id="figobch11appgfig1"><div id="ch11.appg.fig1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Figure%2051.%20Flow%20chart%20of%20health%20economic%20study%20selection%20for%20the%20guideline.&p=BOOKS&id=558771_ch11appgf1.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img data-src="/books/NBK558771/bin/ch11appgf1.jpg" alt="Figure 51. Flow chart of health economic study selection for the guideline." class="tileshop" title="Click on image to zoom" /></a></div><h3><span class="label">Figure 51</span><span class="title">Flow chart of health economic study selection for the guideline</span></h3><div class="caption"><p>* Non-relevant population, intervention, comparison, design or setting; non-English language</p></div></div></article><article data-type="table-wrap" id="figobch11appitab1"><div id="ch11.appi.tab1" class="table"><h3><span class="label">Table 23</span><span class="title">Studies excluded from the clinical review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appi.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appi.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study</th><th id="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Exclusion reason</th></tr></thead><tbody><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adam 2014<a class="bibr" href="#ch11.ref2" rid="ch11.ref2"><sup>2</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Case series</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Adam 2015<a class="bibr" href="#ch11.ref1" rid="ch11.ref1"><sup>1</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not review population. Not Adults (aged 18 years or over) with progressive life limiting conditions thought to be entering their last year of life. Inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ahlner-elmqvist 2004<a class="bibr" href="#ch11.ref4" rid="ch11.ref4"><sup>4</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ahlner-elmqvist 2008<a class="bibr" href="#ch11.ref3" rid="ch11.ref3"><sup>3</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">no relevant outcomes (only baseline measures are reported)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ali 2013<a class="bibr" href="#ch11.ref5" rid="ch11.ref5"><sup>5</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not guideline condition. Not review population</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Almack 2012<a class="bibr" href="#ch11.ref6" rid="ch11.ref6"><sup>6</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Anonymous 1982<a class="bibr" href="#ch11.ref7" rid="ch11.ref7"><sup>7</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (report)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Armstrong 2013<a class="bibr" href="#ch11.ref8" rid="ch11.ref8"><sup>8</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (conference abstract)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Asprey 2013<a class="bibr" href="#ch11.ref9" rid="ch11.ref9"><sup>9</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ayris 2002<a class="bibr" href="#ch11.ref10" rid="ch11.ref10"><sup>10</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not review population. Inappropriate study design (review)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Badger 2009<a class="bibr" href="#ch11.ref11" rid="ch11.ref11"><sup>11</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Badger 2012<a class="bibr" href="#ch11.ref12" rid="ch11.ref12"><sup>12</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bailey 2007<a class="bibr" href="#ch11.ref13" rid="ch11.ref13"><sup>13</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not guideline condition. Not review population. Inappropriate study design (non-comparative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Baker 2012<a class="bibr" href="#ch11.ref14" rid="ch11.ref14"><sup>14</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bakitas 2009<a class="bibr" href="#ch11.ref15" rid="ch11.ref15"><sup>15</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Baldry 2000<a class="bibr" href="#ch11.ref16" rid="ch11.ref16"><sup>16</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Banerjee 2009<a class="bibr" href="#ch11.ref17" rid="ch11.ref17"><sup>17</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Beck-Friis 1993<a class="bibr" href="#ch11.ref18" rid="ch11.ref18"><sup>18</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bekelman 2016<a class="bibr" href="#ch11.ref19" rid="ch11.ref19"><sup>19</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison. Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bernacki 2015<a class="bibr" href="#ch11.ref20" rid="ch11.ref20"><sup>20</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (protocol only)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bernard 2003<a class="bibr" href="#ch11.ref21" rid="ch11.ref21"><sup>21</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Case series</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Baldry 2000<a class="bibr" href="#ch11.ref16" rid="ch11.ref16"><sup>16</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Banerjee 2009<a class="bibr" href="#ch11.ref17" rid="ch11.ref17"><sup>17</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Beck-Friis 1993<a class="bibr" href="#ch11.ref18" rid="ch11.ref18"><sup>18</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bekelman 2016<a class="bibr" href="#ch11.ref19" rid="ch11.ref19"><sup>19</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate comparison. Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bernacki 2015<a class="bibr" href="#ch11.ref20" rid="ch11.ref20"><sup>20</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (protocol only)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Bernard 2003<a class="bibr" href="#ch11.ref21" rid="ch11.ref21"><sup>21</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Case series</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Birks 2011<a class="bibr" href="#ch11.ref22" rid="ch11.ref22"><sup>22</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate outcomes</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Braiteh 2007<a class="bibr" href="#ch11.ref23" rid="ch11.ref23"><sup>23</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Brown 2014<a class="bibr" href="#ch11.ref24" rid="ch11.ref24"><sup>24</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Brumley 2006<a class="bibr" href="#ch11.ref25" rid="ch11.ref25"><sup>25</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Buja 2015<a class="bibr" href="#ch11.ref26" rid="ch11.ref26"><sup>26</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not review population</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Butler 2013<a class="bibr" href="#ch11.ref27" rid="ch11.ref27"><sup>27</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">No relevant outcomes</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Capurro 2014<a class="bibr" href="#ch11.ref28" rid="ch11.ref28"><sup>28</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO. Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Carduff 2014<a class="bibr" href="#ch11.ref29" rid="ch11.ref29"><sup>29</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Carlebach 2010<a class="bibr" href="#ch11.ref30" rid="ch11.ref30"><sup>30</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Carr 2008<a class="bibr" href="#ch11.ref31" rid="ch11.ref31"><sup>31</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Casarett 2008<a class="bibr" href="#ch11.ref32" rid="ch11.ref32"><sup>32</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Casson 2014<a class="bibr" href="#ch11.ref33" rid="ch11.ref33"><sup>33</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Collier 2016<a class="bibr" href="#ch11.ref34" rid="ch11.ref34"><sup>34</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Connolly 2015<a class="bibr" href="#ch11.ref35" rid="ch11.ref35"><sup>35</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Constantini 2003<a class="bibr" href="#ch11.ref36" rid="ch11.ref36"><sup>36</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Czapiuk 2010<a class="bibr" href="#ch11.ref37" rid="ch11.ref37"><sup>37</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dawson 2015<a class="bibr" href="#ch11.ref38" rid="ch11.ref38"><sup>38</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">De bock 2011<a class="bibr" href="#ch11.ref39" rid="ch11.ref39"><sup>39</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Incorrect study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">De san vicente 2015<a class="bibr" href="#ch11.ref40" rid="ch11.ref40"><sup>40</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Detering 2010<a class="bibr" href="#ch11.ref41" rid="ch11.ref41"><sup>41</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dhiliwal 2015<a class="bibr" href="#ch11.ref42" rid="ch11.ref42"><sup>42</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">No relevant outcomes</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dimartino 2014<a class="bibr" href="#ch11.ref43" rid="ch11.ref43"><sup>43</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Doolittle 1998<a class="bibr" href="#ch11.ref45" rid="ch11.ref45"><sup>45</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (report)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Doolittle 2000<a class="bibr" href="#ch11.ref44" rid="ch11.ref44"><sup>44</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. No relevant outcomes</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Downar 2013<a class="bibr" href="#ch11.ref46" rid="ch11.ref46"><sup>46</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Duffy 2018<a class="bibr" href="#ch11.ref47" rid="ch11.ref47"><sup>47</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate outcomes</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Emanuel 1991<a class="bibr" href="#ch11.ref48" rid="ch11.ref48"><sup>48</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not review population. Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Enguidandos 2005<a class="bibr" href="#ch11.ref49" rid="ch11.ref49"><sup>49</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ennis 2015<a class="bibr" href="#ch11.ref50" rid="ch11.ref50"><sup>50</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (non-comparative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fergus 2010<a class="bibr" href="#ch11.ref51" rid="ch11.ref51"><sup>51</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fergus 2010<a class="bibr" href="#ch11.ref51" rid="ch11.ref51"><sup>51</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Finlay 2009<a class="bibr" href="#ch11.ref52" rid="ch11.ref52"><sup>52</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not review population. Incorrect interventions. Inappropriate study design (non-comparative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fontaine 2000<a class="bibr" href="#ch11.ref53" rid="ch11.ref53"><sup>53</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Foster 2001<a class="bibr" href="#ch11.ref54" rid="ch11.ref54"><sup>54</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not guideline condition. Not Adults (aged 18 years or over) with progressive life limiting conditions thought to be entering their last year of life. Not review population</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fredheim 2008<a class="bibr" href="#ch11.ref55" rid="ch11.ref55"><sup>55</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not review population. Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fukui 2011<a class="bibr" href="#ch11.ref56" rid="ch11.ref56"><sup>56</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (survey)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gallagher 2013<a class="bibr" href="#ch11.ref58" rid="ch11.ref58"><sup>58</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gloth 2000<a class="bibr" href="#ch11.ref59" rid="ch11.ref59"><sup>59</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (non-comparative)</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Goldschmidt 2006<a class="bibr" href="#ch11.ref60" rid="ch11.ref60"><sup>60</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gomes 2011<a class="bibr" href="#ch11.ref62" rid="ch11.ref62"><sup>62</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gomes 2013<a class="bibr" href="#ch11.ref61" rid="ch11.ref61"><sup>61</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (narrative review)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gomes 2013<a class="bibr" href="#ch11.ref63" rid="ch11.ref63"><sup>63</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">inappropriate study design (narrative review)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Grabowski 2014<a class="bibr" href="#ch11.ref64" rid="ch11.ref64"><sup>64</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Grady 2003<a class="bibr" href="#ch11.ref65" rid="ch11.ref65"><sup>65</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Grande 1999<a class="bibr" href="#ch11.ref66" rid="ch11.ref66"><sup>66</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Grande 2000<a class="bibr" href="#ch11.ref68" rid="ch11.ref68"><sup>68</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Grande 2000<a class="bibr" href="#ch11.ref68" rid="ch11.ref68"><sup>68</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Grande 2004<a class="bibr" href="#ch11.ref67" rid="ch11.ref67"><sup>67</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Grogan 2016<a class="bibr" href="#ch11.ref69" rid="ch11.ref69"><sup>69</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hall 2013<a class="bibr" href="#ch11.ref70" rid="ch11.ref70"><sup>70</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hanks 2002<a class="bibr" href="#ch11.ref71" rid="ch11.ref71"><sup>71</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Harden 2015<a class="bibr" href="#ch11.ref72" rid="ch11.ref72"><sup>72</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (report)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Harvey 2016<a class="bibr" href="#ch11.ref73" rid="ch11.ref73"><sup>73</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hennemann-Krause 2015<a class="bibr" href="#ch11.ref74" rid="ch11.ref74"><sup>74</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Herrera 2014<a class="bibr" href="#ch11.ref75" rid="ch11.ref75"><sup>75</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hoexum 2012<a class="bibr" href="#ch11.ref76" rid="ch11.ref76"><sup>76</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Holland 2014<a class="bibr" href="#ch11.ref78" rid="ch11.ref78"><sup>78</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not Adults (aged 18 years or over) with progressive life limiting conditions thought to be entering their last year of life. Not guideline condition. Incorrect interventions. Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Horsey 2012<a class="bibr" href="#ch11.ref79" rid="ch11.ref79"><sup>79</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Horwich 2009<a class="bibr" href="#ch11.ref80" rid="ch11.ref80"><sup>80</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not guideline condition. Not review population</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Houben 2014<a class="bibr" href="#ch11.ref81" rid="ch11.ref81"><sup>81</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (protocol only)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Huang 2016<a class="bibr" href="#ch11.ref82" rid="ch11.ref82"><sup>82</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hughes 1990<a class="bibr" href="#ch11.ref83" rid="ch11.ref83"><sup>83</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not guideline condition. Not review population</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hughes 2000<a class="bibr" href="#ch11.ref84" rid="ch11.ref84"><sup>84</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not guideline condition. Not review population. Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Huibers 2009<a class="bibr" href="#ch11.ref85" rid="ch11.ref85"><sup>85</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not guideline condition. Incorrect study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Hull 1991<a class="bibr" href="#ch11.ref86" rid="ch11.ref86"><sup>86</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Jacobsen 2011<a class="bibr" href="#ch11.ref87" rid="ch11.ref87"><sup>87</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">inappropriate comparison</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Johnston 2012<a class="bibr" href="#ch11.ref88" rid="ch11.ref88"><sup>88</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Jones 2007<a class="bibr" href="#ch11.ref89" rid="ch11.ref89"><sup>89</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Joseph 2016<a class="bibr" href="#ch11.ref90" rid="ch11.ref90"><sup>90</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kassakian 1979<a class="bibr" href="#ch11.ref91" rid="ch11.ref91"><sup>91</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kendall 2003<a class="bibr" href="#ch11.ref92" rid="ch11.ref92"><sup>92</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kerr 2006<a class="bibr" href="#ch11.ref93" rid="ch11.ref93"><sup>93</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">King 2000<a class="bibr" href="#ch11.ref94" rid="ch11.ref94"><sup>94</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">King 2003<a class="bibr" href="#ch11.ref95" rid="ch11.ref95"><sup>95</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Klinger 2014<a class="bibr" href="#ch11.ref96" rid="ch11.ref96"><sup>96</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Knight 2007<a class="bibr" href="#ch11.ref97" rid="ch11.ref97"><sup>97</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Laguna 2012<a class="bibr" href="#ch11.ref98" rid="ch11.ref98"><sup>98</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lamont 2016<a class="bibr" href="#ch11.ref99" rid="ch11.ref99"><sup>99</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design. Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lawrence 2011<a class="bibr" href="#ch11.ref100" rid="ch11.ref100"><sup>100</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Leibovitz 2004<a class="bibr" href="#ch11.ref101" rid="ch11.ref101"><sup>101</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lloyd-Williams 2003<a class="bibr" href="#ch11.ref102" rid="ch11.ref102"><sup>102</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lo 2009<a class="bibr" href="#ch11.ref103" rid="ch11.ref103"><sup>103</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. No relevant outcomes</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Luckett 2014<a class="bibr" href="#ch11.ref104" rid="ch11.ref104"><sup>104</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO. Systematic review: literature search not sufficiently rigorous</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Lukas 2013<a class="bibr" href="#ch11.ref105" rid="ch11.ref105"><sup>105</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Macdonald 1994<a class="bibr" href="#ch11.ref106" rid="ch11.ref106"><sup>106</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Magee 2015<a class="bibr" href="#ch11.ref107" rid="ch11.ref107"><sup>107</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative survey)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Main 2006<a class="bibr" href="#ch11.ref108" rid="ch11.ref108"><sup>108</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Marie curie cancer 2012<a class="bibr" href="#ch11.ref109" rid="ch11.ref109"><sup>109</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Masella 2015<a class="bibr" href="#ch11.ref110" rid="ch11.ref110"><sup>110</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mccorkle 1989<a class="bibr" href="#ch11.ref111" rid="ch11.ref111"><sup>111</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mcwhinney 1994<a class="bibr" href="#ch11.ref112" rid="ch11.ref112"><sup>112</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Meier 1995<a class="bibr" href="#ch11.ref113" rid="ch11.ref113"><sup>113</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Miller 1996<a class="bibr" href="#ch11.ref114" rid="ch11.ref114"><sup>114</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not Adults (aged 18 years or over) with progressive life limiting conditions thought to be entering their last year of life. Incorrect interventions. Not review population</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mitchell 2005<a class="bibr" href="#ch11.ref115" rid="ch11.ref115"><sup>115</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mitchell 2014<a class="bibr" href="#ch11.ref116" rid="ch11.ref116"><sup>116</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mohren 2011<a class="bibr" href="#ch11.ref117" rid="ch11.ref117"><sup>117</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Molina 2013<a class="bibr" href="#ch11.ref118" rid="ch11.ref118"><sup>118</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Munday 2002<a class="bibr" href="#ch11.ref119" rid="ch11.ref119"><sup>119</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design (non-comparative survey)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Neergaard 2009<a class="bibr" href="#ch11.ref122" rid="ch11.ref122"><sup>122</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Niemeyer-Guimaraes 2016<a class="bibr" href="#ch11.ref123" rid="ch11.ref123"><sup>123</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Noble 2003<a class="bibr" href="#ch11.ref124" rid="ch11.ref124"><sup>124</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Noble 2015<a class="bibr" href="#ch11.ref125" rid="ch11.ref125"><sup>125</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not relevant to PICO</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Nyatanga 2013<a class="bibr" href="#ch11.ref126" rid="ch11.ref126"><sup>126</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (commentary)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Pesut 2015<a class="bibr" href="#ch11.ref127" rid="ch11.ref127"><sup>127</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Phillips 2008<a class="bibr" href="#ch11.ref128" rid="ch11.ref128"><sup>128</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design. No relevant outcomes</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Pimentel 2013<a class="bibr" href="#ch11.ref129" rid="ch11.ref129"><sup>129</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conference abstract</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Plummer 2011<a class="bibr" href="#ch11.ref130" rid="ch11.ref130"><sup>130</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Porzio 2013<a class="bibr" href="#ch11.ref131" rid="ch11.ref131"><sup>131</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reineck 2013<a class="bibr" href="#ch11.ref134" rid="ch11.ref134"><sup>134</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Hospital based services (not community services)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Richards 2008<a class="bibr" href="#ch11.ref135" rid="ch11.ref135"><sup>135</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Richfield 2014<a class="bibr" href="#ch11.ref136" rid="ch11.ref136"><sup>136</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (abstract only)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rosenquist 1999<a class="bibr" href="#ch11.ref138" rid="ch11.ref138"><sup>138</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Rouhollahi 2015<a class="bibr" href="#ch11.ref139" rid="ch11.ref139"><sup>139</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Schrijnemaekers 2005<a class="bibr" href="#ch11.ref141" rid="ch11.ref141"><sup>141</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Schweitzer 2009<a class="bibr" href="#ch11.ref144" rid="ch11.ref144"><sup>144</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Schweitzer 2011<a class="bibr" href="#ch11.ref142" rid="ch11.ref142"><sup>142</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Schweitzer 2016<a class="bibr" href="#ch11.ref143" rid="ch11.ref143"><sup>143</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Seamark 2014<a class="bibr" href="#ch11.ref145" rid="ch11.ref145"><sup>145</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Shepperd 2009<a class="bibr" href="#ch11.ref147" rid="ch11.ref147"><sup>147</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Shepperd 2011<a class="bibr" href="#ch11.ref149" rid="ch11.ref149"><sup>149</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Shepperd 2016<a class="bibr" href="#ch11.ref148" rid="ch11.ref148"><sup>148</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sheppherd 1998<a class="bibr" href="#ch11.ref150" rid="ch11.ref150"><sup>150</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Shields 1996<a class="bibr" href="#ch11.ref151" rid="ch11.ref151"><sup>151</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (report)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Shimada 2016<a class="bibr" href="#ch11.ref152" rid="ch11.ref152"><sup>152</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Shipman 2000<a class="bibr" href="#ch11.ref153" rid="ch11.ref153"><sup>153</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design (non-comparative survey)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Shipman 2003<a class="bibr" href="#ch11.ref154" rid="ch11.ref154"><sup>154</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Skilbeck 2005<a class="bibr" href="#ch11.ref155" rid="ch11.ref155"><sup>155</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Slack 2015<a class="bibr" href="#ch11.ref156" rid="ch11.ref156"><sup>156</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design (narrative review)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Smeenk 1998<a class="bibr" href="#ch11.ref157" rid="ch11.ref157"><sup>157</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<p>Systematic review: literature search not sufficiently rigorous.</p>
|
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<p>Systematic review is not relevant to review question or unclear PICO</p>
|
|
</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Smith 2014<a class="bibr" href="#ch11.ref158" rid="ch11.ref158"><sup>158</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Stewart 2011<a class="bibr" href="#ch11.ref159" rid="ch11.ref159"><sup>159</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Incorrect interventions. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sulistio 2015<a class="bibr" href="#ch11.ref160" rid="ch11.ref160"><sup>160</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Not guideline condition</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Swetenham 2014<a class="bibr" href="#ch11.ref161" rid="ch11.ref161"><sup>161</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Takahashi 2012<a class="bibr" href="#ch11.ref162" rid="ch11.ref162"><sup>162</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Tam 2014<a class="bibr" href="#ch11.ref163" rid="ch11.ref163"><sup>163</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Tan 2014<a class="bibr" href="#ch11.ref164" rid="ch11.ref164"><sup>164</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO. Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Taubert 2010<a class="bibr" href="#ch11.ref165" rid="ch11.ref165"><sup>165</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Taubert 2010<a class="bibr" href="#ch11.ref166" rid="ch11.ref166"><sup>166</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design (qualitative study)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Taubert 2011<a class="bibr" href="#ch11.ref167" rid="ch11.ref167"><sup>167</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Taylor Jr 2013<a class="bibr" href="#ch11.ref168" rid="ch11.ref168"><sup>168</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Teno 2004<a class="bibr" href="#ch11.ref169" rid="ch11.ref169"><sup>169</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">The national council for palliative 2011<a class="bibr" href="#ch11.ref170" rid="ch11.ref170"><sup>170</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design (report)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Thoonsen 2011<a class="bibr" href="#ch11.ref171" rid="ch11.ref171"><sup>171</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Todd 2002<a class="bibr" href="#ch11.ref172" rid="ch11.ref172"><sup>172</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Tramarin 1992<a class="bibr" href="#ch11.ref173" rid="ch11.ref173"><sup>173</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Travers 2002<a class="bibr" href="#ch11.ref174" rid="ch11.ref174"><sup>174</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (intervention design; no results reported)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Travis 2015<a class="bibr" href="#ch11.ref175" rid="ch11.ref175"><sup>175</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (commentary)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Van Gurp 2015<a class="bibr" href="#ch11.ref176" rid="ch11.ref176"><sup>176</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Van Heest 2007<a class="bibr" href="#ch11.ref177" rid="ch11.ref177"><sup>177</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative cohort study)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Van Riet Paap 2014<a class="bibr" href="#ch11.ref178" rid="ch11.ref178"><sup>178</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (study protocol)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Waller 2008<a class="bibr" href="#ch11.ref179" rid="ch11.ref179"><sup>179</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Waller 2009<a class="bibr" href="#ch11.ref180" rid="ch11.ref180"><sup>180</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Conference abstract</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Waller 2010<a class="bibr" href="#ch11.ref181" rid="ch11.ref181"><sup>181</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect interventions. Inappropriate study design (protocol)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Walsh 1992<a class="bibr" href="#ch11.ref182" rid="ch11.ref182"><sup>182</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (report)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Walshe 2008<a class="bibr" href="#ch11.ref183" rid="ch11.ref183"><sup>183</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (qualitative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wiese 2009<a class="bibr" href="#ch11.ref184" rid="ch11.ref184"><sup>184</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Wilkes 2004<a class="bibr" href="#ch11.ref185" rid="ch11.ref185"><sup>185</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inappropriate study design (non-comparative)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Worth 2006<a class="bibr" href="#ch11.ref186" rid="ch11.ref186"><sup>186</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design (qualitative study)</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Zimmer 1982<a class="bibr" href="#ch11.ref187" rid="ch11.ref187"><sup>187</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Not review population. Inappropriate study design</td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Zimmer 1985<a class="bibr" href="#ch11.ref188" rid="ch11.ref188"><sup>188</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Not review population</td></tr><tr><td headers="hd_h_ch11.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Zimmermann 2008<a class="bibr" href="#ch11.ref189" rid="ch11.ref189"><sup>189</sup></a></td><td headers="hd_h_ch11.appi.tab1_1_1_1_2" colspan="2" rowspan="1" style="text-align:left;vertical-align:top;">Systematic review is not relevant to review question or unclear PICO</td></tr></tbody></table></div></div></article><article data-type="table-wrap" id="figobch11appitab2"><div id="ch11.appi.tab2" class="table"><h3><span class="label">Table 24</span><span class="title">Studies excluded from the health economic review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK558771/table/ch11.appi.tab2/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch11.appi.tab2_lrgtbl__"><table><thead><tr><th id="hd_h_ch11.appi.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reference</th><th id="hd_h_ch11.appi.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reason for exclusion</th></tr></thead><tbody><tr><td headers="hd_h_ch11.appi.tab2_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gage 2015<a class="bibr" href="#ch11.ref57" rid="ch11.ref57"><sup>57</sup></a></td><td headers="hd_h_ch11.appi.tab2_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was assessed as partially applicable with very serious limitations. It is not a cost utility analysis and the cost analysis does not take into account the cost of the intervention itself.</td></tr></tbody></table></div></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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