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<meta name="robots" content="INDEX,FOLLOW,NOARCHIVE" /><meta name="citation_inbook_title" content="StatPearls [Internet]" /><meta name="citation_title" content="Abrasion" /><meta name="citation_publisher" content="StatPearls Publishing" /><meta name="citation_date" content="2023/08/17" /><meta name="citation_author" content="Rijen Shrestha" /><meta name="citation_author" content="Kewal Krishan" /><meta name="citation_author" content="Husnain Ishaq" /><meta name="citation_author" content="Tanuj Kanchan" /><meta name="citation_pmid" content="32119352" /><meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK554465/" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Abrasion" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="StatPearls Publishing" /><meta name="DC.Contributor" content="Rijen Shrestha" /><meta name="DC.Contributor" content="Kewal Krishan" /><meta name="DC.Contributor" content="Husnain Ishaq" /><meta name="DC.Contributor" content="Tanuj Kanchan" /><meta name="DC.Date" content="2023/08/17" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK554465/" /><meta name="description" content="Abrasions are superficial injuries that occur on the skin and visceral linings of the body, disrupting tissue continuity. They are typically minor wounds, mainly limited to the epidermis, and usually do not cause significant bleeding. Most abrasions heal without leaving any scars. However, if the abrasion extends into the dermis, it may result in scar tissue formation during the healing process." /><meta name="og:title" content="Abrasion" /><meta name="og:type" content="book" /><meta name="og:description" content="Abrasions are superficial injuries that occur on the skin and visceral linings of the body, disrupting tissue continuity. They are typically minor wounds, mainly limited to the epidermis, and usually do not cause significant bleeding. Most abrasions heal without leaving any scars. However, if the abrasion extends into the dermis, it may result in scar tissue formation during the healing process." /><meta name="og:url" content="https://www.ncbi.nlm.nih.gov/books/NBK554465/" /><meta name="og:site_name" content="NCBI Bookshelf" /><meta name="og:image" content="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-statpearls-lrg.png" /><meta name="twitter:card" content="summary" /><meta name="twitter:site" content="@ncbibooks" /><meta name="bk-non-canon-loc" content="/books/n/statpearls/article-17040/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK554465/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" /><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript">window.name="mainwindow";</script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script>
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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. </p></div></div></div>
<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK554465_"><span class="title" itemprop="name">Abrasion</span></h1><p class="contrib-group"><h4>Authors</h4><span itemprop="author">Rijen Shrestha</span><sup>1</sup>; <span itemprop="author">Kewal Krishan</span><sup>2</sup>; <span itemprop="author">Husnain Ishaq</span><sup>3</sup>; <span itemprop="author">Tanuj Kanchan</span><sup>4</sup>.</p><h4>Affiliations</h4><div class="affiliation"><sup>1</sup> Department of Anthropology, Panjab University, Chandigarh, India</div><div class="affiliation"><sup>2</sup> Department of Anthropology (UGC Centre of Advanced Study), Panjab University, Chandigarh, India</div><div class="affiliation"><sup>3</sup> Mayo Hospital, Lahore</div><div class="affiliation"><sup>4</sup> Department of Forensic Medicine, All India Institute of Medical Sciences, Jodhpur, India</div><p class="small">Last Update: <span itemprop="dateModified">August 17, 2023</span>.</p></div><div class="body-content whole_rhythm" itemprop="text"><div id="article-17040.s1"><h2 id="_article-17040_s1_">Continuing Education Activity</h2><p>Abrasion is the superficial denudation of the epithelium due to scraping, impact, or pressure. The majority of abrasions heal without leaving any scars. However, the abrasions that extend into the dermis may result in tissue scarring&#x000a0;after healing. Abrasions appear in all forms of blunt trauma, with friction and impact being the most common mechanisms. While managing abrasions is relatively simple, there can be&#x000a0;significant medico-legal considerations. This activity discusses&#x000a0;the evaluation and management of abrasion and highlights the role of the interprofessional team in managing this condition.</p><p>
<b>Objectives:</b>
<ul><li class="half_rhythm"><div>Identify the characteristics and features of abrasions, including their appearance, size, location, and associated injuries.</div></li><li class="half_rhythm"><div>Assess the severity and extent of abrasions, including involvement of deeper structures, to determine the need for further evaluation, referral, or specialized care.</div></li><li class="half_rhythm"><div>Select and utilize appropriate tools, instruments, and materials for wound management, including dressings, sutures, adhesive agents, and topical medications, based on patient-specific needs and wound characteristics.</div></li><li class="half_rhythm"><div>Coordinate multidisciplinary care for patients with severe or complicated abrasions, involving specialists from various disciplines, such as orthopedic surgery, dermatology, or infectious disease, to provide comprehensive and coordinated care.</div></li></ul>
<a href="https://www.statpearls.com/account/trialuserreg/?articleid=17040&#x00026;utm_source=pubmed&#x00026;utm_campaign=reviews&#x00026;utm_content=17040" ref="pagearea=body&amp;targetsite=external&amp;targetcat=link&amp;targettype=uri">Access free multiple choice questions on this topic.</a>
</p></div><div id="article-17040.s2"><h2 id="_article-17040_s2_">Introduction</h2><p>Abrasions are superficial injuries&#x000a0;that occur on the skin and visceral linings&#x000a0;of the body, disrupting tissue continuity. They are typically minor wounds, mainly limited to the epidermis, and usually do not cause significant bleeding. Most abrasions heal without leaving any scars. However, if the abrasion extends into the dermis, it may result in scar tissue formation during the healing process.</p><p>Abrasions most commonly occur due to friction against the epidermis, leading to the denudation of the outer layer. Abrasions appear in&#x000a0;various&#x000a0;forms of blunt trauma, with friction and impact being the most common mechanisms. While less frequent, pressure abrasions can have a greater medicolegal significance, especially for identifying the causative material.</p></div><div id="article-17040.s3"><h2 id="_article-17040_s3_">Etiology</h2><p>Abrasions are classified into&#x000a0;3 types based on clinical presentations and etiological factors. These include linear or scratch abrasions, grazed or brush abrasions, and patterned abrasions.&#x000a0;Impact abrasions result from a swift blow and&#x000a0;forceful&#x000a0;blow. Patterned abrasions resulting from blows, collisions, and auto versus pedestrian accidents are examples of impact abrasions.<a class="bk_pop" href="#article-17040.r1">[1]</a><a class="bk_pop" href="#article-17040.r2">[2]</a></p><p>
<b>Linear or Scratch Abrasions</b>
</p><p>Linear abrasions&#x000a0;occur when&#x000a0;tangential forces cause the epidermis to be stripped away.&#x000a0;They are the simplest injuries&#x000a0;that typically heal by primary intention, without any sequelae.<a class="bk_pop" href="#article-17040.r3">[3]</a> Linear abrasions hold significant medicolegal importance, especially in specific areas such as the neck, inner thighs, and genitalia. Linear or semicircular injuries are classically seen as a result of nail scratches, and their presence on the inner aspect of thighs and around female genitalia may indicate resistance in cases of sexual assault. Likewise, nail scratch abrasions on the neck may&#x000a0;suggest strangulation.<a class="bk_pop" href="#article-17040.r4">[4]</a><a class="bk_pop" href="#article-17040.r5">[5]</a><a class="bk_pop" href="#article-17040.r6">[6]</a></p><p>
<b>Grazed or Brush Abrasions</b>
</p><p>Grazed abrasions usually occur in multiple presentations and result from friction against a broad, rough surface. These are most commonly&#x000a0;observed in&#x000a0;incidents such&#x000a0;as road traffic accidents and falls during sports activities. Grazed abrasions are caused by&#x000a0;the body being&#x000a0;dragged&#x000a0;against a rough surface,&#x000a0;leading to the scraping off&#x000a0;of the epidermis. The depth of grazed injuries varies depending on the surface's irregularity and the body's speed. Extensive, grazed abrasions are sometimes referred to as "brush burns."<a class="bk_pop" href="#article-17040.r7">[7]</a></p><p>
<b>Patterned Abrasion</b>
</p><p>Patterned abrasions occur when perpendicular force is applied to&#x000a0;the epidermis, resulting in an impression of the offending object. Depending on the duration of contact with the offending object, they can be further subclassified as pressure abrasion and impact abrasion. Pressure abrasions result from prolonged compression of the epidermis, and they require minimal force to occur. For example, a ligature mark produced using roughing material for hanging leaves an imprint of the material used.<a class="bk_pop" href="#article-17040.r8">[8]</a>&#x000a0;</p></div><div id="article-17040.s4"><h2 id="_article-17040_s4_">Epidemiology</h2><p>Abrasions can occur at any&#x000a0;stage of life without a specific preference&#x000a0;for any age or sex.&#x000a0;They are primarily accidental across all age groups. However, abrasions caused by intentional injuries are more&#x000a0;prevalent among individuals in middle age compared to those in the extremes of age. Intentional injuries related to sexual offenses are more common in females. Unintentional abrasions are frequently associated with falls and sports-related injuries&#x000a0;in children, while falls&#x000a0;are a&#x000a0;prevalent cause among&#x000a0;older patients.&#x000a0;</p><p>Abrasions are the most common form of injury in children accounting for 70.7% of all reported injuries. The head and torso are the primary sites, comprising 50% of all recorded abrasions. The upper limbs account for 15.4%,&#x000a0;while the lower limbs&#x000a0;comprise about&#x000a0;34.6% of all reported cases.<a class="bk_pop" href="#article-17040.r9">[9]</a> However, there exists a&#x000a0;potential for&#x000a0;significant underreporting of the overall prevalence of abrasions and their predilection for a particular site, as people sustaining minor abrasions or scratches on nonvital parts of the body do not often seek medical attention at clinics and hospitals for their management.</p></div><div id="article-17040.s5"><h2 id="_article-17040_s5_">Pathophysiology</h2><p>Abrasions can vary in severity,&#x000a0;ranging from a break in the superficial epithelial lining to damage affecting deeper structures, including nerves, blood vessels, muscles, tendons,&#x000a0;organs, and even bone.<a class="bk_pop" href="#article-17040.r10">[10]</a><a class="bk_pop" href="#article-17040.r11">[11]</a></p><p>Forensic investigations may be necessary to&#x000a0;assess the extent of the injury and the antemortem or postmortem nature of the wound. The presence of vital reactions,&#x000a0;such as hemorrhage, cell infiltration, and granulation tissue,&#x000a0;provide valuable indicators&#x000a0;of the antemortem quality of an abrasion.<a class="bk_pop" href="#article-17040.r12">[12]</a></p></div><div id="article-17040.s6"><h2 id="_article-17040_s6_">Histopathology</h2><p>While histopathology of abrasions is rarely performed, it&#x000a0;can be valuable&#x000a0;in&#x000a0;determining the&#x000a0;healing stage of the injury. This information can be&#x000a0;correlated&#x000a0;with the patient's history, particularly in medicolegal cases,&#x000a0;to&#x000a0;establish the date and time of the injury occurrence.&#x000a0;<a class="bk_pop" href="#article-17040.r13">[13]</a></p></div><div id="article-17040.s7"><h2 id="_article-17040_s7_">History and Physical</h2><p>When evaluating a patient with abrasions, relevant history should be documented, including the time, cause, and mechanism of injury. Gathering additional details related to the factors contributing to the injury is also crucial. Additionally, the patients' tetanus vaccine status should be determined as well.</p><p>Abrasions are&#x000a0;frequently&#x000a0;linked&#x000a0;to physical trauma, often due to falls, impacts against hard&#x000a0;or uneven surfaces, and the pressure exerted by objects. They are commonly&#x000a0;observed&#x000a0;with other forms of blunt force trauma, including contusions and lacerations.</p><p>While&#x000a0;a physical examination of abrasions is&#x000a0;essential for treatment, the medicolegal examination holds even greater significance. Abrasions&#x000a0;can be&#x000a0;found&#x000a0;on any body part but are commonly observed&#x000a0;on exposed areas&#x000a0;such as&#x000a0;the head, neck, and extremities. When&#x000a0;located on the&#x000a0;neck or genitalia, abrasions may have a particular significance that requires further evaluation.</p><p>The physical examination of abrasions should include&#x000a0;assessing their&#x000a0;type, size, shape, color, location, depth, and potential association with other injuries.&#x000a0;Assessing for the presence of extraneous material is crucial. Scientifically&#x000a0;collecting and evaluating these extraneous materials can&#x000a0;yield valuable information for crime scene investigation, establishing a connection between the suspect and the crime.&#x000a0;&#x000a0;</p><p>The systematic management of injuries, for medical and medicolegal purposes, will ensure not just treatment of the injury but also may&#x000a0;support potential future legal proceedings. The medicolegal examination is critical when dealing with injuries to&#x000a0;the head, neck, and genitalia. Injuries around the genitalia could be vital in identifying cases of sexual violence, while minor injuries over the head and neck may&#x000a0;indicate the presence&#x000a0;of more serious underlying injuries.</p></div><div id="article-17040.s8"><h2 id="_article-17040_s8_">Evaluation</h2><p>The&#x000a0;evaluation of minor wounds begins&#x000a0;by determining the mechanism and timing of the injury while also considering the possible presence of a foreign body.&#x000a0;A comprehensive&#x000a0;visual inspection of the affected area is performed to identify any visible foreign objects. In some settings, radiographs may be&#x000a0;necessary to&#x000a0;detect&#x000a0;radiopaque foreign bodies, while ultrasound can help identify non-radiopaque ones.</p><p>If the wound is full thickness, the extent of the abrasion should be determined, including any damage to neurovascular structures, muscles, or tendons. This assessment&#x000a0;may involve checking pulses and capillary refills in the area of the wound.&#x000a0;A neurological evaluation should&#x000a0;also be conducted, encompassing&#x000a0;motor and sensory testing. Depending on the nature and location of the abrasion, there may be&#x000a0;aesthetic concerns that&#x000a0;warrant further evaluation for cosmesis.</p><p>The medicolegal investigation may require a biopsy of the abrasion&#x000a0;to conduct a histological examination. The histological examination investigates the stage of wound healing to provide an estimate of the time of injury. The wound healing process involves coordinated cellular changes, including bleeding and coagulation, inflammatory response, regeneration, and remodeling. The regeneration process further involves migration and proliferation, while remodeling involves extracellular matrix protein and collagen synthesis and the formation of new parenchymal and connective tissue. These processes are four time-dependent phases:</p><ol><li class="half_rhythm"><div>Bleeding and coagulation, which&#x000a0;initiate immediately</div></li><li class="half_rhythm"><div>Inflammation also begins promptly.</div></li><li class="half_rhythm"><div>Regeneration&#x000a0;commences&#x000a0;within days and lasts&#x000a0;throughout the primary part of the acute healing phase.</div></li><li class="half_rhythm"><div>Remodeling, which begins weeks after the injury and can&#x000a0;persist for longer than a year.<a class="bk_pop" href="#article-17040.r10">[10]</a><a class="bk_pop" href="#article-17040.r12">[12]</a><a class="bk_pop" href="#article-17040.r14">[14]</a></div></li></ol><p>The information may be further augmented by histochemical analysis of inflammatory cells and cell mediators. This analysis&#x000a0;can assist in determining the time of injury, providing insights to law enforcement.&#x000a0;Histopathology of an injury can provide vital information for any potential investigation.<a class="bk_pop" href="#article-17040.r15">[15]</a><a class="bk_pop" href="#article-17040.r16">[16]</a><a class="bk_pop" href="#article-17040.r17">[17]</a><a class="bk_pop" href="#article-17040.r18">[18]</a></p></div><div id="article-17040.s9"><h2 id="_article-17040_s9_">Treatment / Management</h2><p>Abrasions are usually&#x000a0;uncomplicated&#x000a0;and frequently small in size. The first step in treatment is to irrigate the area with water or saline. These abrasions usually heal through primary intention and do not leave any scarring. However, the involvement of a large surface area&#x000a0;may lead to healing by secondary intention, resulting in scar formation. This is mainly&#x000a0;observed in individuals susceptible to keloid hyperplasia, and intralesional corticosteroid therapy may be considered to prevent keloid formation in these patients.</p><p>Abrasions are usually minor injuries that do not require&#x000a0;extensive&#x000a0;medical intervention. A sponsored study&#x000a0;has shown that wet healing, using polyurethane and hydrocolloid plasters, is a more efficient and effective approach to wound healing.<a class="bk_pop" href="#article-17040.r19">[19]</a></p><p>Due to the loss of the protective epidermal layer, abrasions are particularly&#x000a0;vulnerable to <i>Clostridium tetani</i> and <i>Staphylococcus aureus </i>infection, particularly in sports-related injuries. Tetanus toxoid&#x000a0;immunization&#x000a0;should continually be updated if needed. Abrasions should be cleansed and dressed to protect the area against reinjury. Debridement may be necessary, especially if dirt or other contaminants are embedded. Prevention of infection is the primary objective of medical intervention. In cases where there are no known allergies, antibiotic ointments may be applied.</p><p>The use of dressings depends on the&#x000a0;location and depth of the injury. Systemic antibiotics may be indicated for some patients. However,&#x000a0;given the increasing prevalence&#x000a0;of antibiotic resistance among various organisms, it is essential to maintain strict follow-up to&#x000a0;assess compliance and adherence to the complete treatment protocol. Swabbing and sending the injury for culture and sensitivity analysis may also be necessary to guide appropriate antibiotic therapy.</p><p>Facial abrasions are considered more serious&#x000a0;due to the increased&#x000a0;risk of cicatrization and should be cleaned, debrided, and dressed daily. Dressings may require skin adhesives&#x000a0;such as a combination of gum mastic, styrax, alcohol, methyl salicylate, or tincture of benzoin.<a class="bk_pop" href="#article-17040.r20">[20]</a></p></div><div id="article-17040.s10"><h2 id="_article-17040_s10_">Differential Diagnosis</h2><p>The patient's history and the mechanism of injury&#x000a0;often&#x000a0;provide important clues for&#x000a0;diagnosing an abrasion. The presence of foreign material may&#x000a0;offer insights into&#x000a0;the&#x000a0;cause and nature of the injury. Abrasions occurring over the eyes, including the conjunctiva,&#x000a0;may be mistakenly attributed to various&#x000a0;ocular conditions, including conjunctivitis, corneal ulcer, and endophthalmitis.<a class="bk_pop" href="#article-17040.r21">[21]</a><a class="bk_pop" href="#article-17040.r22">[22]</a></p><p>During&#x000a0;medico-legal examinations, the nature of the abrasion is more important than the&#x000a0;severity&#x000a0;of the injury. The location of the abrasion may present significant findings and could be a vital piece of evidence. Injuries&#x000a0;observed on&#x000a0;the neck may&#x000a0;suggest an (attempted) homicide case. Similarly, injuries present over the thighs and genitalia could indicate a case of sexual assault.</p></div><div id="article-17040.s11"><h2 id="_article-17040_s11_">Prognosis</h2><p>Abrasions are generally minor injuries&#x000a0;that tend to heal within 2 weeks without any resultant scarring. However, in cases of extensive and deep abrasions or if infection occurs, scarring may result. This can be&#x000a0;prevented by daily cleaning and dressing. Debridement should be performed to avoid extensive cicatrization.</p></div><div id="article-17040.s12"><h2 id="_article-17040_s12_">Complications</h2><p>Wound infection is a common complication associated with abrasions.<a class="bk_pop" href="#article-17040.r23">[23]</a>&#x000a0;Proper wound cleaning is essential. Local antibiotic ointments may be applied to superficial, contaminated wounds. However, systemic antibiotics may be necessary to prevent secondary infections in large and deep abrasions.<a class="bk_pop" href="#article-17040.r24">[24]</a>&#x000a0;Weighing the need to prevent infection against increased antibiotic resistance is essential.&#x000a0;The patient's tetanus immunization should be assessed and updated as needed.</p><p>Extensive and deep abrasions&#x000a0;can&#x000a0;form wide and persistent scars&#x000a0;that may&#x000a0;last&#x000a0;for months or years. Individuals prone to&#x000a0;keloid formation&#x000a0;may&#x000a0;develop extensive scarring, especially on the chest and shoulders.<a class="bk_pop" href="#article-17040.r25">[25]</a></p><p>The nature and&#x000a0;context of abrasions are essential aspects&#x000a0;that require&#x000a0;adequate attention from clinicians to&#x000a0;avoid potential negligence claims.&#x000a0;Proper documentation, including photography of the injuries, should be preserved for a specified period.</p></div><div id="article-17040.s13"><h2 id="_article-17040_s13_">Deterrence and Patient Education</h2><p>Abrasions occur&#x000a0;due to various causes, ranging from innocuous incidents to grievous injuries. Patients and relatives&#x000a0;must&#x000a0;be educated&#x000a0;about the medicolegal importance of these seemingly inconsequential injuries. Clinicians should also recognize the importance of thorough documentation. In sports, abrasions can be reduced by&#x000a0;implementing protective measures such as using protective gear, padding, and appropriate clothing.</p><p>Simple abrasions&#x000a0;caused&#x000a0;by falls can be&#x000a0;managed&#x000a0;with first aid. Patients and their relatives should receive education on proper first aid procedures,&#x000a0;which include cleaning the wound,&#x000a0;removing any&#x000a0;foreign material, and dressing with a non-adhesive material.</p></div><div id="article-17040.s14"><h2 id="_article-17040_s14_">Enhancing Healthcare Team Outcomes </h2><p>Abrasions are&#x000a0;among the most frequently encountered physical injuries. While many are&#x000a0;superficial and&#x000a0;can be managed at home with simple treatments, healthcare workers will likely encounter patients with abrasions requiring medical attention.&#x000a0;It is important to note that abrasions often coexist with other injuries. The presence of abrasions should&#x000a0;initiate a&#x000a0;thorough investigation, and the abrasions should be managed with clinical and medicolegal considerations.</p><p>Emergency medical technicians, trauma nurses, and clinicians may conduct the initial assessment of abrasions. Emergency department and ambulatory care nurses provide direct care and educate patients. Pharmacists&#x000a0;may counsel patients regarding over-the-counter and prescription medications for abrasions.&#x000a0;Maintaining vigilant monitoring and documentation throughout the care process is essential&#x000a0;for&#x000a0;clinical and medicolegal case management.</p></div><div id="article-17040.s15"><h2 id="_article-17040_s15_">Review Questions</h2><ul><li class="half_rhythm"><div>
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When a suicide becomes a forensic enigma: The role of hanging marks and tools of suspension. <span><span class="ref-journal">Med Leg J. </span>2017 Sep;<span class="ref-vol">85</span>(3):141-144.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/28849696" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 28849696</span></a>]</div></dd><dt>9.</dt><dd><div class="bk_ref" id="article-17040.r9">Tiagi C, Walia I, Singh A. Prevalence of minor injuries among underfives in a Chandigarh slum. <span><span class="ref-journal">Indian Pediatr. </span>2000 Jul;<span class="ref-vol">37</span>(7):755-8.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/10906808" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 10906808</span></a>]</div></dd><dt>10.</dt><dd><div class="bk_ref" id="article-17040.r10">Velnar T, Bailey T, Smrkolj V. The wound healing process: an overview of the cellular and molecular mechanisms. <span><span class="ref-journal">J Int Med Res. </span>2009 Sep-Oct;<span class="ref-vol">37</span>(5):1528-42.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/19930861" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 19930861</span></a>]</div></dd><dt>11.</dt><dd><div class="bk_ref" id="article-17040.r11">Alonso JE, Lee J, Burgess AR, Browner BD. The management of complex orthopedic injuries. <span><span class="ref-journal">Surg Clin North Am. </span>1996 Aug;<span class="ref-vol">76</span>(4):879-903.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/8782479" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 8782479</span></a>]</div></dd><dt>12.</dt><dd><div class="bk_ref" id="article-17040.r12">Rivera AE, Spencer JM. Clinical aspects of full-thickness wound healing. <span><span class="ref-journal">Clin Dermatol. </span>2007 Jan-Feb;<span class="ref-vol">25</span>(1):39-48.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/17276200" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 17276200</span></a>]</div></dd><dt>13.</dt><dd><div class="bk_ref" id="article-17040.r13">Robertson I, Hodge PR. Histopathology of healing abrasions. <span><span class="ref-journal">Forensic Sci. </span>1972 Apr;<span class="ref-vol">1</span>(1):17-25.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/5054821" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 5054821</span></a>]</div></dd><dt>14.</dt><dd><div class="bk_ref" id="article-17040.r14">Gantwerker EA, Hom DB. Skin: histology and physiology of wound healing. <span><span class="ref-journal">Facial Plast Surg Clin North Am. </span>2011 Aug;<span class="ref-vol">19</span>(3):441-53.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/21856533" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 21856533</span></a>]</div></dd><dt>15.</dt><dd><div class="bk_ref" id="article-17040.r15">Betz P. Histological and enzyme histochemical parameters for the age estimation of human skin wounds. <span><span class="ref-journal">Int J Legal Med. </span>1994;<span class="ref-vol">107</span>(2):60-8.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/7529545" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 7529545</span></a>]</div></dd><dt>16.</dt><dd><div class="bk_ref" id="article-17040.r16">Fronczek J, Lulf R, Korkmaz HI, Witte BI, van de Goot FR, Begieneman MP, Schalkwijk CG, Krijnen PA, Rozendaal L, Niessen HW, Reijnders UJ. Analysis of inflammatory cells and mediators in skin wound biopsies to determine wound age in living subjects in forensic medicine. <span><span class="ref-journal">Forensic Sci Int. </span>2015 Feb;<span class="ref-vol">247</span>:7-13.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/25506669" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 25506669</span></a>]</div></dd><dt>17.</dt><dd><div class="bk_ref" id="article-17040.r17">Raekallio J. Determination of the age of wounds by histochemical and biochemical methods. <span><span class="ref-journal">Forensic Sci. </span>1972 Apr;<span class="ref-vol">1</span>(1):3-16.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/4341073" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 4341073</span></a>]</div></dd><dt>18.</dt><dd><div class="bk_ref" id="article-17040.r18">Uz&#x000fc;n I, Akyildiz E, Inanici MA. Histopathological differentiation of skin lesions caused by electrocution, flame burns and abrasion. <span><span class="ref-journal">Forensic Sci Int. </span>2008 Jul 04;<span class="ref-vol">178</span>(2-3):157-61.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/18472235" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 18472235</span></a>]</div></dd><dt>19.</dt><dd><div class="bk_ref" id="article-17040.r19">Wigger-Alberti W, Kuhlmann M, Ekanayake S, Wilhelm D. Using a novel wound model to investigate the healing properties of products for superficial wounds. <span><span class="ref-journal">J Wound Care. </span>2009 Mar;<span class="ref-vol">18</span>(3):123-28, 131.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/19247233" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 19247233</span></a>]</div></dd><dt>20.</dt><dd><div class="bk_ref" id="article-17040.r20">Lanzi GL. Facial Injuries in Sports, Soft Tissue Injuries (Abrasions, Contusions, Lacerations). <span><span class="ref-journal">Clin Sports Med. </span>2017 Apr;<span class="ref-vol">36</span>(2):287-298.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/28314418" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 28314418</span></a>]</div></dd><dt>21.</dt><dd><div class="bk_ref" id="article-17040.r21">Sliwicki AL, Orringer K. Corneal Abrasions. <span><span class="ref-journal">Pediatr Rev. </span>2023 Jun 01;<span class="ref-vol">44</span>(6):343-345.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/37258882" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 37258882</span></a>]</div></dd><dt>22.</dt><dd><div class="bk_ref" id="article-17040.r22">Meer E, Grob S, Antonsen EL, Sawyer A. Ocular conditions and injuries, detection and management in spaceflight. <span><span class="ref-journal">NPJ Microgravity. </span>2023 May 16;<span class="ref-vol">9</span>(1):37.</span> [<a href="/pmc/articles/PMC10188687/" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pmc">PMC free article<span class="bk_prnt">: PMC10188687</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/37193709" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 37193709</span></a>]</div></dd><dt>23.</dt><dd><div class="bk_ref" id="article-17040.r23">Diaz JH. Skin and soft tissue infections following marine injuries and exposures in travelers. <span><span class="ref-journal">J Travel Med. </span>2014 May-Jun;<span class="ref-vol">21</span>(3):207-13.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/24628985" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 24628985</span></a>]</div></dd><dt>24.</dt><dd><div class="bk_ref" id="article-17040.r24">Chin YK, Ina-Salwany MY, Zamri-Saad M, Amal MNA, Mohamad A, Lee JY, Annas S, Al-Saari N. Effects of skin abrasion in immersion challenge with Vibrio harveyi in Asian seabass Lates calcarifer fingerlings. <span><span class="ref-journal">Dis Aquat Organ. </span>2020 Jan 16;<span class="ref-vol">137</span>(3):167-173.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/31942862" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 31942862</span></a>]</div></dd><dt>25.</dt><dd><div class="bk_ref" id="article-17040.r25">Knowles A, Glass DA. Keloids and Hypertrophic Scars. <span><span class="ref-journal">Dermatol Clin. </span>2023 Jul;<span class="ref-vol">41</span>(3):509-517.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/37236718" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 37236718</span></a>]</div></dd></dl></div><div><dl class="temp-labeled-list small"><dt></dt><dd><div><p class="no_top_margin">
<b>Disclosure: </b>Rijen Shrestha declares no relevant financial relationships with ineligible companies.</p></div></dd><dt></dt><dd><div><p class="no_top_margin">
<b>Disclosure: </b>Kewal Krishan declares no relevant financial relationships with ineligible companies.</p></div></dd><dt></dt><dd><div><p class="no_top_margin">
<b>Disclosure: </b>Husnain Ishaq declares no relevant financial relationships with ineligible companies.</p></div></dd><dt></dt><dd><div><p class="no_top_margin">
<b>Disclosure: </b>Tanuj Kanchan declares no relevant financial relationships with ineligible companies.</p></div></dd></dl></div><div class="bk_prnt_sctn"><h2>Figures</h2><div class="whole_rhythm bk_prnt_obj bk_first_prnt_obj"><div id="article-17040.image.f1" class="figure bk_fig"><div class="graphic"><a href="/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Image%20OU201300112AU004&amp;p=BOOKS&amp;id=554465_OU201300112AU004.jpg" target="tileshopwindow" class="inline_block pmc_inline_block ts_canvas img_link" title="Click on image to zoom"><div class="ts_bar small" title="Click on image to zoom"></div><img src="/books/NBK554465/bin/OU201300112AU004.jpg" alt="Image OU201300112AU004" class="tileshop" title="Click on image to zoom" /></a></div><div class="caption"><p>Parallel, Linear Abrasions of the Ventral Aspects of the Right Wrist Contributed by Andrea L Wiens, DO</p></div></div></div><div class="whole_rhythm bk_prnt_obj"><div id="article-17040.image.f2" class="figure bk_fig"><div class="graphic"><img src="/books/NBK554465/bin/800pxHandAbrasion16hours45minutesafterinjury.jpg" alt="Image 800pxHandAbrasion16hours45minutesafterinjury" /></div><div class="caption"><p>Abrasion caused by sliding fall on concrete Contributed by Wikimedia Commons (Public Domain)</p></div></div></div><div class="whole_rhythm bk_prnt_obj"><div id="article-17040.image.f3" class="figure bk_fig"><div class="graphic"><img src="/books/NBK554465/bin/abrasion2.jpg" alt="A patient with bruises and abrasion" /></div><div class="caption"><p>A patient with bruises and abrasion. Contributed by Depositphotos (Royalty free, non-copyrighted for fair and commercial use)</p></div></div></div><div class="whole_rhythm bk_prnt_obj"><div id="article-17040.image.f4" class="figure bk_fig"><div class="graphic"><img src="/books/NBK554465/bin/depositphotos131962024.jpg" alt="A patient with scratch abrasions" /></div><div class="caption"><p>A patient with scratch abrasions. Contributed by Depositphotos (Royalty free, non-copyrighted for fair and commercial use)</p></div></div></div></div></div></div>
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