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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p></div><div class="bk_msg_box bk_bttm_mrgn clearfix bk_noprnt"><div class="iconblock clearfix"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/niceng206guid/"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-niceng206guid-lrg.png" alt="Cover" height="100px" width="80px" /></a><div class="icnblk_cntnt"><ul class="messages"><li class="info icon"><span class="icon"><a href="/books/n/niceng206guid/">A new version of this title is available</a></span></li></ul></div></div></div><div class="messagearea bk_noprnt" style="margin-bottom:1.3846em "><ul class="messages"><li class="warn icon"><span class="icon">This publication is provided for historical reference only and the information may be out of date.</span></li></ul></div><div class="bk_prnt"><p style="color:red;"><strong>This publication is provided for historical reference only and the information may be out of date.</strong></p></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/Book"><div class="meta-content fm-sec"><div class="iconblock whole_rhythm clearfix no_top_margin"><a href="http://www.rcgp.org.uk/" title="Royal College of General Practitioners (UK)" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg53-lrg.png" alt="Cover of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (or Encephalopathy)" /></a><div class="icnblk_cntnt"><h1 id="_NBK53577_"><span itemprop="name">Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (or Encephalopathy)</span></h1><div class="subtitle">Diagnosis and Management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (or Encephalopathy) in Adults and Children</div><p><i>NICE Clinical Guidelines, No. 53</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">National Collaborating Centre for Primary Care (UK)</span>.</p><div class="half_rhythm">London: <a href="http://www.rcgp.org.uk/" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">Royal College of General Practitioners (UK)</span></a>; <span itemprop="datePublished">2007 Aug</span>.</div><div><a href="/books/about/copyright/">Copyright</a> © 2007, Royal College of General Practitioners.</div></div></div></div><div class="body-content whole_rhythm" itemprop="text"><div itemprop="description"><h2>Excerpt</h2><p>The guideline covers care provided by healthcare professionals who have direct contact with and make decisions about the care of people with chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy) (CFS/ME). It covers care provided in primary and secondary care, and in specialist centres/teams.</p><p>The Guideline Development Group (GDG) developed this guideline with the aims of: increasing the recognition of CFS/ME; influencing practice in the ‘real world’; improving access to appropriate services, and supporting consistent service provision; emphasising the need for multidisciplinary working; improving care for patients, particularly for those with severe CFS/ME; providing guidance on ‘best practice’ for children with CFS/ME; balancing clinical guidance with flexibility and management tailored to the needs of the patient; facilitating communication between practitioners and patients, and their families or carers, as appropriate.</p></div><div><h2>Contents</h2><ul id="toc_tllNBK53577_nicecg53_preface" class="simple-list toc toc-toggle"><li class="half_rhythm" id="toc_itm_NBK53577_nicecg53_preface"><a href="/books/n/nicecg53/nicecg53.preface/" class="toc-item">Preface</a></li><li class="half_rhythm" id="toc_itm_NBK53577_nicecg53_acknowledgements"><a href="/books/n/nicecg53/nicecg53.acknowledgements/" class="toc-item">Acknowledgements</a></li><li class="half_rhythm" id="toc_itm_NBK53577_abbreviations"><a href="/books/n/nicecg53/abbreviations/" class="toc-item">Abbreviations</a></li><li class="half_rhythm" id="toc_itm_NBK53577_glossary"><a href="/books/n/nicecg53/glossary/" class="toc-item">Glossary of terms</a></li><li class="half_rhythm" id="toc_itm_NBK53577_guideline"><a href="/books/n/nicecg53/guideline/" class="toc-item">Guideline Development Group (GDG)</a></li><li class="half_rhythm" id="toc_itm_NBK53577_executivesummary"><a href="/books/n/nicecg53/executivesummary/" class="toc-item">Executive summary and recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK53577_structureoftheguideline"><a href="/books/n/nicecg53/structureoftheguideline/" class="toc-item">Structure of the guideline documentation</a></li><li class="half_rhythm" id="toc_itm_NBK53577_development"><a href="/books/n/nicecg53/development/" class="toc-item">Development of the guideline</a></li><li class="half_rhythm" id="toc_itm_NBK53577_scope"><a href="/books/n/nicecg53/scope/" class="toc-item">Scope</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1"><a href="/books/n/nicecg53/ch1/" class="toc-item">1. Introduction to chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy)</a><ul id="toc_lst_NBK53577_ch1_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s1"><a href="/books/n/nicecg53/ch1/#ch1.s1" class="toc-item">1.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s2"><a href="/books/n/nicecg53/ch1/#ch1.s2" class="toc-item">1.2 Clinical need for the guideline</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s3"><a href="/books/n/nicecg53/ch1/#ch1.s3" class="toc-item">1.3 Aetiology</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s4"><a href="/books/n/nicecg53/ch1/#ch1.s4" class="toc-item">1.4 Diagnosis</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s5"><a href="/books/n/nicecg53/ch1/#ch1.s5" class="toc-item">1.5 Management</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s6"><a href="/books/n/nicecg53/ch1/#ch1.s6" class="toc-item">1.6 Prognosis</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s7"><a href="/books/n/nicecg53/ch1/#ch1.s7" class="toc-item">1.7 Epidemiology</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch1_s9"><a href="/books/n/nicecg53/ch1/#ch1.s9" class="toc-item">1.8 Existing service provision</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2"><a href="/books/n/nicecg53/ch2/" class="toc-item">2. Methodology</a><ul id="toc_lst_NBK53577_ch2_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s1"><a href="/books/n/nicecg53/ch2/#ch2.s1" class="toc-item">2.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s2"><a href="/books/n/nicecg53/ch2/#ch2.s2" class="toc-item">2.2 The developers</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s3"><a href="/books/n/nicecg53/ch2/#ch2.s3" class="toc-item">2.3 The Guideline Development Group (GDG)</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s4"><a href="/books/n/nicecg53/ch2/#ch2.s4" class="toc-item">2.4 Developing key clinical questions</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s5"><a href="/books/n/nicecg53/ch2/#ch2.s5" class="toc-item">2.5 Layout of chapters 4–7</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s6"><a href="/books/n/nicecg53/ch2/#ch2.s6" class="toc-item">2.6 Identifying the evidence</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s10"><a href="/books/n/nicecg53/ch2/#ch2.s10" class="toc-item">2.7 Reviewing and grading the evidence</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s13"><a href="/books/n/nicecg53/ch2/#ch2.s13" class="toc-item">2.8 Developing evidence statements and recommendations using formal consensus methods</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s16"><a href="/books/n/nicecg53/ch2/#ch2.s16" class="toc-item">2.9 Use of the consensus methodology in guideline development</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s24"><a href="/books/n/nicecg53/ch2/#ch2.s24" class="toc-item">2.10 Developing recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch2_s25"><a href="/books/n/nicecg53/ch2/#ch2.s25" class="toc-item">2.11 External review</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK53577_ch3"><a href="/books/n/nicecg53/ch3/" class="toc-item">3. The experience of people with CFS/ME</a><ul id="toc_lst_NBK53577_ch3_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK53577_ch3_s1"><a href="/books/n/nicecg53/ch3/#ch3.s1" class="toc-item">3.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch3_s2"><a href="/books/n/nicecg53/ch3/#ch3.s2" class="toc-item">3.2 Summary of submissions by stakeholder organisations</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch3_s14"><a href="/books/n/nicecg53/ch3/#ch3.s14" class="toc-item">3.3 Personal testimonies from people with CFS/ME</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK53577_ch4"><a href="/books/n/nicecg53/ch4/" class="toc-item">4. General principles of care</a><ul id="toc_lst_NBK53577_ch4_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK53577_ch4_s1"><a href="/books/n/nicecg53/ch4/#ch4.s1" class="toc-item">4.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch4_s2"><a href="/books/n/nicecg53/ch4/#ch4.s2" class="toc-item">4.2 Recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch4_s7"><a href="/books/n/nicecg53/ch4/#ch4.s7" class="toc-item">4.3 Information</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch4_s15"><a href="/books/n/nicecg53/ch4/#ch4.s15" class="toc-item">4.4 Support</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK53577_ch5"><a href="/books/n/nicecg53/ch5/" class="toc-item">5. Making a diagnosis of CFS/ME</a><ul id="toc_lst_NBK53577_ch5_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK53577_ch5_s1"><a href="/books/n/nicecg53/ch5/#ch5.s1" class="toc-item">5.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch5_s14"><a href="/books/n/nicecg53/ch5/#ch5.s14" class="toc-item">5.2 Arriving at a diagnosis</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch5_s41"><a href="/books/n/nicecg53/ch5/#ch5.s41" class="toc-item">5.3 Referral to specialist CFS/ME care</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch5_s52"><a href="/books/n/nicecg53/ch5/#ch5.s52" class="toc-item">5.4 A conceptual framework for patients, carers and healthcare professionals when making a diagnosis of CFS/ME</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK53577_ch6"><a href="/books/n/nicecg53/ch6/" class="toc-item">6. Management</a><ul id="toc_lst_NBK53577_ch6_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK53577_ch6_s1"><a href="/books/n/nicecg53/ch6/#ch6.s1" class="toc-item">6.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch6_s2"><a href="/books/n/nicecg53/ch6/#ch6.s2" class="toc-item">6.2 Key clinical question 3 and subquestion 3</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch6_s3"><a href="/books/n/nicecg53/ch6/#ch6.s3" class="toc-item">6.3 CBT, GET, activity management and other therapeutic interventions</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch6_s70"><a href="/books/n/nicecg53/ch6/#ch6.s70" class="toc-item">6.4 Pharmacological interventions</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch6_s89"><a href="/books/n/nicecg53/ch6/#ch6.s89" class="toc-item">6.5 Dietary interventions and supplements</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch6_s101"><a href="/books/n/nicecg53/ch6/#ch6.s101" class="toc-item">6.6 Complementary therapies</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch6_s113"><a href="/books/n/nicecg53/ch6/#ch6.s113" class="toc-item">6.7 Review and ongoing management</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK53577_ch7"><a href="/books/n/nicecg53/ch7/" class="toc-item">7. People with severe CFS/ME</a><ul id="toc_lst_NBK53577_ch7_s1" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK53577_ch7_s1"><a href="/books/n/nicecg53/ch7/#ch7.s1" class="toc-item">7.1 Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch7_s2"><a href="/books/n/nicecg53/ch7/#ch7.s2" class="toc-item">7.2 Purpose and context of this chapter</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch7_s3"><a href="/books/n/nicecg53/ch7/#ch7.s3" class="toc-item">7.3 General recommendations</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch7_s8"><a href="/books/n/nicecg53/ch7/#ch7.s8" class="toc-item">7.4 Additional information related to Chapter 4 – General principles of care</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch7_s15"><a href="/books/n/nicecg53/ch7/#ch7.s15" class="toc-item">7.5 Additional information related to Chapter 5 – Making a diagnosis of CFS/ME</a></li><li class="half_rhythm" id="toc_itm_NBK53577_ch7_s19"><a href="/books/n/nicecg53/ch7/#ch7.s19" class="toc-item">7.6 Additional information related to Chapter 6 – Management</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK53577_references_rl1"><a href="/books/n/nicecg53/references.rl1/" class="toc-item">References</a></li><li class="half_rhythm" id="toc_itm_NBK53577_appendixes_app1"><a href="/books/n/nicecg53/appendixes.app1/" class="toc-item">Appendix 1 Systematic Evidence Review to support the development of the NICE clinical guideline for CFS/ME in adults and children</a></li><li class="half_rhythm" id="toc_itm_NBK53577_appendixes_app2"><a href="/books/n/nicecg53/appendixes.app2/" class="toc-item">Appendix 2 Data extraction tables</a></li><li class="half_rhythm" id="toc_itm_NBK53577_appendixes_app3"><a href="/books/n/nicecg53/appendixes.app3/" class="toc-item">Appendix 3 Questionnaires</a></li><li class="half_rhythm" id="toc_itm_NBK53577_appendixes_app4"><a href="/books/n/nicecg53/appendixes.app4/" class="toc-item">Appendix 4 Background letters and instructions related to the questionnaire</a></li></ul></div><div><h4 class="inline">Suggested citation:</h4><p>Turnbull N, Shaw EJ, Baker R, Dunsdon S, Costin N, Britton G, Kuntze S and Norman R (2007). Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management of chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy) in adults and children. London: Royal College of General Practitioners.</p></div></div></div>
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<div class="post-content"><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> © 2007, Royal College of General Practitioners.</div><div class="small"><span class="label">Bookshelf ID: NBK53577</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/21563329" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">21563329</a></span></div><div style="margin-top:2em" class="bk_noprnt"><div class="pagination bk_noprnt"><span class="inactive page_link prev">< Prev</span><a class="active page_link next" href="/books/n/nicecg53/nicecg53.preface/" title="Next page in this title">Next ></a></div></div></div></div>
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<!--<component id="Breadcrumbs" label="breadcrumbs"/>
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<component id="Breadcrumbs" label="helpdesk"/>-->
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</div>
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<script type="text/javascript" src="/portal/portal3rc.fcgi/rlib/js/InstrumentNCBIBaseJS/InstrumentPageStarterJS.js"> </script>
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</div>
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</div>
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<!--/.page-->
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</div>
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<!--/.wrap-->
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</div><!-- /.twelve_col -->
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</div>
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<!-- /.grid -->
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<span class="PAFAppResources"></span>
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<!-- BESelector tab -->
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<noscript><img alt="statistics" src="/stat?jsdisabled=true&ncbi_db=books&ncbi_pdid=book-toc&ncbi_acc=NBK53577&ncbi_domain=nicecg53&ncbi_report=printable&ncbi_type=fulltext&ncbi_objectid=&ncbi_pcid=/NBK53577/?report=printable&ncbi_app=bookshelf" /></noscript>
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<!-- usually for JS scripts at page bottom -->
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<!--<component id="PageFixtures" label="styles"></component>-->
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<!-- CE8B5AF87C7FFCB1_0191SID /projects/books/PBooks@9.11 portal105 v4.1.r689238 Tue, Oct 22 2024 16:10:51 -->
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<span id="portal-csrf-token" style="display:none" data-token="CE8B5AF87C7FFCB1_0191SID"></span>
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<script type="text/javascript" src="//static.pubmed.gov/portal/portal3rc.fcgi/4216699/js/3879255/4121861/3501987/4008961/3893018/3821238/3400083/3426610.js" snapshot="books"></script></body>
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</html> |